Met_transgene_Two_brain_sample_analysis
LC/Qiu lab
2022-09-12
Initialize relevant libraries
Import libaries for analysis
# setwd("D:/BioinformaticsProjects/sc_exp6")
library(Seurat)
library(dplyr)
library(cowplot)
library(ggplot2)
library(rstatix)
library(SingleCellExperiment)
library(ComplexHeatmap)
library(RColorBrewer)
library(circlize)
library(patchwork)Import two samples; m10 = M3N, m11 = M3P
To minimize change of coding, keep the existing variable names as much as possile. Copy the slim_counts/ files to the m10 and m11 folder under ‘./slim_counts’
Quality Control
Quality assessment before filtering
Joint filtering effects:
Quality assessment after filtering
Selecting Data Subset
Filter data based on these criteria: nFeature_RNA < 7500& nFeature_RNA>75 & nCount_RNA > 1000 and then, added the filtering criteria of “percent.mt < 20” After subseting, only keeping those genes expressed in more than 20 cells
The dimension of pooled data is:20147, 43690
Reassess quality metrics
Quality metrics after filtered counts
Apply sctransform normalization
This steps can replace NormalizeData(),
ScaleData(), and FindVariableFeatures(). The
results of sctransform are stored in the “SCT” assay. It is assumed to
reveals sharper biological distinctions compared to the standard Seurat
workflow.
Since it is a normalization step, we have to do
separately for two different samples (that’s why split seurat objects
here), then only integrate the sample expression data in the next step,
integration analysis, to remove batch effect.
Integration of two samples
Select the most variable features to use for integration, we
will use 3000 features and IntegratData
Clustering
Run the standard workflow for linear and non-linear reduction, visualization and clustering
We use a resolution vector c(0.05, 0.5) for cluster identification, which seems appropriate for this sample size ~13K cells
Clustering quality control
This step gives us some idea about how is the distribution of the number of genes, number of UMIs, and percentage of mitochondrial genes in each cluster. Normally, we expect to see similar distribution of no. of genes (nFeature_RNA) and no. of UMIs (nCount_RNA).
As for the percent.mt (percentage of mitochondrial genes per cell), it can be a reference to check if those high intensity clusters might be having poor quality cells (if so, we can try to remove in the next step or adjust the metrics in the previous filtering step) or it might be due to the differences biologically.
Determine metrics to plot present in seurat_integrated@meta.data
NOTE from SQ: for certain feature if not found in ‘integrated’ assay (may only have 2000 high variable features), you need to switch to “RNA” or “SCT” assay using DefaultAssay(seurat_integrated) <- “RNA”
Find all markers in two samples for cell type identification
Write all gene markers to a .csv file on local drive
Plotting top markers for each cluster
Setting up plotting parameters
##Violin plot for selected gene markers
For example, genes in the MAPK pathway
Define genes of interest and do heatmaps
Find markers for specific cluster in two samples for cell type identification
Identifying cell type
Option 1: SingleR package with built-in reference
I use a collection of mouse bulk RNA-seq data sets obtained from celldex package (Benayoun et al. 2019). A variety of cell types are available, mostly from blood but also covering several other tissues. This identifies marker genes from the reference and uses them to compute assignment scores (based on the Spearman correlation across markers) for each cell in the test dataset against each label in the reference. The label with the highest score is the assigned to the test cell, possibly with further fine-tuning to resolve closely related labels.
This reference consists of a collection of mouse bulk RNA-seq data sets downloaded from the gene expression omnibus Benayoun et al. 2019. A variety of cell types are available, again mostly from blood but also covering several other tissues.
Option 2: manual annotation
Plotting Astrocyte Markers
Plotting Microglia Markers
Plotting Endothelial Markers
Plotting Oligodendrocyte Markers
Plotting Glutamatergic Neuron Markers
Plotting Gabaergic Neuron Markers
Plotting Oligodendrocyte Precursor Markers
Rename cluster based on the SingleR results and manual annotation
Option 3: manual annotation
Refer to Tasic et al, Nature 2018, [marker list] https://github.com/AllenInstitute/tasic2018analysis/blob/master/RNA-seq%20Analysis/markers.R
Differential expression Analysis for groups
Now we do a DEG analysis for all genes between the two groups
## [[1]]
## p_val avg_log2FC pct.1 pct.2 p_val_adj comparison
## Calb2 0.000000e+00 -1.5795937 0.130 0.020 0.000000e+00 CTL_MUT
## Fos 0.000000e+00 -2.9854102 0.211 0.151 0.000000e+00 CTL_MUT
## Btg2 0.000000e+00 0.2841740 0.187 0.072 0.000000e+00 CTL_MUT
## Junb 0.000000e+00 6.6319571 0.168 0.162 0.000000e+00 CTL_MUT
## Pbld1 0.000000e+00 -3.5895251 0.245 0.013 0.000000e+00 CTL_MUT
## Grp 0.000000e+00 6.4704216 0.144 0.065 0.000000e+00 CTL_MUT
## Megf11 0.000000e+00 -10.6721401 0.184 0.052 0.000000e+00 CTL_MUT
## Gm34544 0.000000e+00 -5.0438383 0.259 0.045 0.000000e+00 CTL_MUT
## Ddr1 0.000000e+00 7.7412903 0.220 0.067 0.000000e+00 CTL_MUT
## 1700034P13Rik 0.000000e+00 -3.3170392 0.236 0.028 0.000000e+00 CTL_MUT
## Cd68 0.000000e+00 -5.9694697 0.217 0.019 0.000000e+00 CTL_MUT
## Phlda3 0.000000e+00 -0.3583806 0.188 0.063 0.000000e+00 CTL_MUT
## Btk 0.000000e+00 -3.9188411 0.237 0.021 0.000000e+00 CTL_MUT
## F11r 0.000000e+00 -1.6861058 0.165 0.021 0.000000e+00 CTL_MUT
## 9430041J12Rik 0.000000e+00 -0.7618627 0.168 0.051 0.000000e+00 CTL_MUT
## Btg1 0.000000e+00 3.0170114 0.199 0.115 0.000000e+00 CTL_MUT
## Pbxip1 0.000000e+00 -1.3053547 0.228 0.050 0.000000e+00 CTL_MUT
## Ltbp4 0.000000e+00 1.6072044 0.179 0.073 0.000000e+00 CTL_MUT
## Pla2g6 0.000000e+00 -2.1057494 0.264 0.031 0.000000e+00 CTL_MUT
## Adam2 0.000000e+00 7.3887109 0.188 0.088 0.000000e+00 CTL_MUT
## Atg4a 0.000000e+00 -9.6076075 0.257 0.064 0.000000e+00 CTL_MUT
## Vipr2 0.000000e+00 8.5414909 0.276 0.011 0.000000e+00 CTL_MUT
## Npnt 0.000000e+00 8.9826449 0.168 0.061 0.000000e+00 CTL_MUT
## Npas4 0.000000e+00 -0.2681409 0.214 0.070 0.000000e+00 CTL_MUT
## Myh3 0.000000e+00 -1.7828812 0.214 0.019 0.000000e+00 CTL_MUT
## Ddit4 5.752959e-308 -6.2493524 0.203 0.069 1.725888e-304 CTL_MUT
## Etnppl 1.917865e-307 14.7789637 0.205 0.033 5.753594e-304 CTL_MUT
## Slc44a1 2.076025e-305 0.6022486 0.315 0.261 6.228074e-302 CTL_MUT
## Angptl4 2.596479e-301 4.8506813 0.203 0.011 7.789438e-298 CTL_MUT
## Selenbp1 1.771488e-298 -2.9470895 0.259 0.009 5.314464e-295 CTL_MUT
## Nr2e1 6.119989e-297 -1.8698337 0.246 0.013 1.835997e-293 CTL_MUT
## Cers2 2.274562e-290 -7.6280746 0.177 0.058 6.823685e-287 CTL_MUT
## Notch1 1.976132e-289 -0.7020505 0.192 0.053 5.928396e-286 CTL_MUT
## Myo1e 5.704031e-287 3.7221430 0.204 0.061 1.711209e-283 CTL_MUT
## Meig1 7.538056e-284 -0.2777956 0.219 0.011 2.261417e-280 CTL_MUT
## Hes5 2.488217e-270 -14.9456772 0.165 0.063 7.464652e-267 CTL_MUT
## Cplx3 6.933186e-270 -1.4380575 0.191 0.029 2.079956e-266 CTL_MUT
## Cd24a 1.917880e-268 0.4950403 0.168 0.024 5.753641e-265 CTL_MUT
## Pstpip2 4.006886e-268 -4.6749814 0.178 0.047 1.202066e-264 CTL_MUT
## Sox10 1.582160e-264 -2.5397199 0.169 0.051 4.746479e-261 CTL_MUT
## Limd1 4.881906e-263 -17.2779191 0.226 0.041 1.464572e-259 CTL_MUT
## Ccnb1 4.014260e-261 -0.7021224 0.227 0.032 1.204278e-257 CTL_MUT
## Rnf220 3.698258e-260 2.3987696 0.235 0.234 1.109477e-256 CTL_MUT
## Parvb 1.536086e-258 -0.5196863 0.188 0.035 4.608259e-255 CTL_MUT
## Itih3 6.261427e-258 3.5995798 0.192 0.035 1.878428e-254 CTL_MUT
## Myh9 3.394307e-257 -1.9637386 0.182 0.080 1.018292e-253 CTL_MUT
## Rap1a 6.219264e-251 1.8346877 0.226 0.172 1.865779e-247 CTL_MUT
## Arpc1b 9.843572e-251 -3.3050166 0.180 0.073 2.953072e-247 CTL_MUT
## Arhgap29 1.218510e-249 1.2885641 0.142 0.047 3.655529e-246 CTL_MUT
## Csrp1 2.327036e-249 -1.9513557 0.210 0.136 6.981109e-246 CTL_MUT
## Lgals9 1.113302e-248 -3.4689039 0.183 0.024 3.339907e-245 CTL_MUT
## Adipor2 2.935784e-247 -1.4072640 0.187 0.112 8.807353e-244 CTL_MUT
## Pcdh11x 1.290093e-245 2.4869852 0.299 0.239 3.870278e-242 CTL_MUT
## Nos1 4.226874e-239 0.5603435 0.188 0.036 1.268062e-235 CTL_MUT
## Nwd1 8.860394e-236 -0.4590588 0.161 0.104 2.658118e-232 CTL_MUT
## Kazn 1.912526e-235 -8.3495900 0.194 0.087 5.737579e-232 CTL_MUT
## Pacs2 6.203060e-233 3.3974789 0.192 0.079 1.860918e-229 CTL_MUT
## Gnb4 1.052023e-231 -4.0051086 0.181 0.088 3.156069e-228 CTL_MUT
## Cd83 1.016752e-230 -4.8241922 0.112 0.037 3.050255e-227 CTL_MUT
## Gprc5b 4.685291e-229 9.6887944 0.211 0.062 1.405587e-225 CTL_MUT
## Tubb4a 1.326646e-228 0.2918736 0.317 0.334 3.979938e-225 CTL_MUT
## Dhdh 6.740570e-228 -4.7699705 0.272 0.013 2.022171e-224 CTL_MUT
## Des 3.929953e-227 0.6785676 0.139 0.003 1.178986e-223 CTL_MUT
## Shoc1 8.517468e-227 -2.7547089 0.182 0.007 2.555240e-223 CTL_MUT
## Steap3 2.613294e-226 6.5907626 0.198 0.008 7.839881e-223 CTL_MUT
## Tpm2 8.791483e-226 -0.8342918 0.202 0.009 2.637445e-222 CTL_MUT
## Clec2d 4.428359e-225 4.4384481 0.152 0.022 1.328508e-221 CTL_MUT
## Pou3f4 3.649726e-224 6.9714511 0.245 0.014 1.094918e-220 CTL_MUT
## Matn4 6.996128e-224 1.6010655 0.196 0.029 2.098838e-220 CTL_MUT
## Sncaip 1.505031e-220 7.5405953 0.194 0.031 4.515094e-217 CTL_MUT
## Foxn3 9.337646e-220 -1.1041740 0.373 0.304 2.801294e-216 CTL_MUT
## D16Ertd472e 2.848921e-218 -2.3468178 0.178 0.044 8.546762e-215 CTL_MUT
## St6galnac3 4.282307e-216 -2.5406608 0.361 0.282 1.284692e-212 CTL_MUT
## Ucp2 3.718274e-213 -1.2019967 0.126 0.081 1.115482e-209 CTL_MUT
## Smad7 3.047849e-212 -0.4853771 0.175 0.093 9.143547e-209 CTL_MUT
## 4930563F08Rik 8.896128e-212 -10.1545368 0.144 0.003 2.668838e-208 CTL_MUT
## Fxyd5 2.227483e-211 -1.2949810 0.182 0.045 6.682450e-208 CTL_MUT
## Ddr2 1.643932e-208 -4.4637538 0.226 0.011 4.931796e-205 CTL_MUT
## Sox2 1.571969e-207 -4.0056650 0.195 0.060 4.715908e-204 CTL_MUT
## Tnfrsf26 3.979563e-207 -1.0664102 0.065 0.231 1.193869e-203 CTL_MUT
## Josd2 4.911988e-207 -1.0264245 0.203 0.132 1.473596e-203 CTL_MUT
## Rtkn 2.693440e-206 -2.6253321 0.187 0.063 8.080319e-203 CTL_MUT
## D630033O11Rik 1.044294e-203 7.4385537 0.230 0.008 3.132883e-200 CTL_MUT
## C77080 1.333474e-203 -0.6574878 0.217 0.030 4.000422e-200 CTL_MUT
## Plekha1 2.666727e-203 -0.6536832 0.277 0.216 8.000182e-200 CTL_MUT
## Zfhx4 1.413524e-202 -0.8891921 0.172 0.096 4.240571e-199 CTL_MUT
## Cdk19 1.735338e-202 1.1531584 0.254 0.216 5.206014e-199 CTL_MUT
## Gfap 1.826520e-198 -3.0655461 0.151 0.050 5.479561e-195 CTL_MUT
## Slc9a3r2 2.535763e-198 -0.4254209 0.156 0.086 7.607290e-195 CTL_MUT
## Grn 2.239813e-196 -3.9468858 0.164 0.095 6.719439e-193 CTL_MUT
## Arhgef10 4.817850e-196 -2.7607670 0.188 0.061 1.445355e-192 CTL_MUT
## Otud7b 6.396009e-196 -0.4812728 0.241 0.162 1.918803e-192 CTL_MUT
## Bcl2l1 9.127496e-196 0.3317420 0.247 0.181 2.738249e-192 CTL_MUT
## Ccm2l 1.448041e-195 -5.0059896 0.100 0.005 4.344124e-192 CTL_MUT
## Phgdh 9.394483e-195 -0.6128013 0.206 0.086 2.818345e-191 CTL_MUT
## Slc7a5 1.941032e-194 -2.9769079 0.137 0.074 5.823095e-191 CTL_MUT
## Gm4258 3.942581e-193 -0.9580059 0.316 0.257 1.182774e-189 CTL_MUT
## Gsta4 1.527294e-192 2.4455924 0.139 0.076 4.581882e-189 CTL_MUT
## Fosb 2.008792e-192 -5.9186821 0.195 0.035 6.026376e-189 CTL_MUT
## 1700047M11Rik 1.286090e-191 -1.3783797 0.162 0.065 3.858271e-188 CTL_MUT
## Nfe2l2 2.131547e-190 -3.2893304 0.163 0.056 6.394642e-187 CTL_MUT
## Ier2 4.977405e-190 5.5882163 0.196 0.063 1.493221e-186 CTL_MUT
## Gab1 4.850021e-189 -4.9284730 0.191 0.090 1.455006e-185 CTL_MUT
## Endod1 7.014453e-188 -1.3317714 0.186 0.115 2.104336e-184 CTL_MUT
## Bst2 3.057038e-187 -1.8378038 0.186 0.016 9.171113e-184 CTL_MUT
## Ccp110 1.753377e-186 -5.6385797 0.185 0.084 5.260130e-183 CTL_MUT
## Pcdh9 4.554943e-186 -2.5137860 0.497 0.386 1.366483e-182 CTL_MUT
## Gbp7 8.344175e-186 6.1866052 0.168 0.013 2.503253e-182 CTL_MUT
## Fgfr1 4.188393e-185 2.3213292 0.177 0.073 1.256518e-181 CTL_MUT
## Net1 2.959550e-184 6.0672826 0.134 0.052 8.878651e-181 CTL_MUT
## Tmeff2 2.071293e-183 -7.6943784 0.412 0.349 6.213880e-180 CTL_MUT
## Gm29521 1.728065e-182 5.3239515 0.252 0.010 5.184194e-179 CTL_MUT
## Wasf2 5.936312e-182 -1.7160939 0.206 0.100 1.780894e-178 CTL_MUT
## Gm10635 6.313338e-180 -2.0763586 0.107 0.023 1.894001e-176 CTL_MUT
## Rasal3 2.771180e-179 4.9246520 0.111 0.004 8.313539e-176 CTL_MUT
## Dock6 2.806688e-179 4.5060150 0.186 0.018 8.420064e-176 CTL_MUT
## Nfasc 4.245922e-179 -2.6153976 0.351 0.323 1.273777e-175 CTL_MUT
## Maf 1.763475e-178 10.1587178 0.136 0.132 5.290425e-175 CTL_MUT
## Cdc42ep4 1.281237e-177 2.0018987 0.236 0.015 3.843710e-174 CTL_MUT
## Ltc4s 1.761039e-175 2.5251722 0.121 0.051 5.283118e-172 CTL_MUT
## Slc12a2 1.067325e-174 -6.4249470 0.234 0.170 3.201976e-171 CTL_MUT
## Foxo1 6.691514e-174 -9.2678239 0.167 0.062 2.007454e-170 CTL_MUT
## Mitf 2.031625e-172 -1.9622126 0.216 0.089 6.094876e-169 CTL_MUT
## Raver2 2.959837e-172 -5.1679590 0.153 0.054 8.879511e-169 CTL_MUT
## Rgma 1.449542e-171 -1.0568867 0.204 0.049 4.348626e-168 CTL_MUT
## Efnb3 7.822437e-171 -3.3460235 0.179 0.077 2.346731e-167 CTL_MUT
## Stxbp3 2.071676e-170 -4.6263133 0.193 0.087 6.215027e-167 CTL_MUT
## Sema4d 2.629784e-170 0.4429087 0.221 0.160 7.889351e-167 CTL_MUT
## Nefm 3.747394e-170 -3.1530120 0.157 0.112 1.124218e-166 CTL_MUT
## Prelp 4.474887e-170 1.4858473 0.171 0.009 1.342466e-166 CTL_MUT
## Gpr160 4.509344e-170 -8.1686584 0.101 0.005 1.352803e-166 CTL_MUT
## Pde4b 1.487915e-169 -7.1577308 0.426 0.357 4.463745e-166 CTL_MUT
## Slc7a11 3.462198e-169 -5.8507072 0.141 0.077 1.038659e-165 CTL_MUT
## Fgfr2 2.499567e-168 -0.7483811 0.373 0.319 7.498701e-165 CTL_MUT
## Tcap 3.084438e-168 -0.9751068 0.170 0.024 9.253315e-165 CTL_MUT
## Il33 6.475349e-168 -0.3533059 0.230 0.025 1.942605e-164 CTL_MUT
## Eya1 1.131130e-167 -3.3957105 0.172 0.054 3.393389e-164 CTL_MUT
## Pou3f1 2.011647e-167 2.1333338 0.151 0.075 6.034942e-164 CTL_MUT
## Cast 5.808601e-167 2.8768794 0.180 0.022 1.742580e-163 CTL_MUT
## Crip1 6.283239e-167 -1.5094433 0.157 0.030 1.884972e-163 CTL_MUT
## Cacng4 7.395531e-167 -5.4692882 0.151 0.058 2.218659e-163 CTL_MUT
## Folh1 3.031092e-166 5.0979741 0.188 0.021 9.093277e-163 CTL_MUT
## Cnn3 8.209264e-166 -0.8969109 0.198 0.070 2.462779e-162 CTL_MUT
## Elovl7 1.306929e-164 -7.4731880 0.170 0.061 3.920788e-161 CTL_MUT
## Emid1 3.186401e-164 1.6972036 0.205 0.028 9.559202e-161 CTL_MUT
## Tmem176a 2.099574e-163 2.0249459 0.193 0.047 6.298721e-160 CTL_MUT
## Ddah2 7.973387e-162 -1.4116930 0.209 0.037 2.392016e-158 CTL_MUT
## Dusp15 1.352761e-161 1.0537810 0.194 0.068 4.058284e-158 CTL_MUT
## Ifi30 1.256490e-159 5.8138129 0.189 0.011 3.769470e-156 CTL_MUT
## Phactr4 4.419679e-159 5.1211235 0.204 0.063 1.325904e-155 CTL_MUT
## Agt 1.700120e-158 4.2968697 0.233 0.010 5.100360e-155 CTL_MUT
## Tmem82 4.949340e-158 9.9227418 0.163 0.006 1.484802e-154 CTL_MUT
## Sgk1 6.512736e-158 -1.1499242 0.297 0.250 1.953821e-154 CTL_MUT
## Gimap1 1.740906e-157 1.2585357 0.153 0.007 5.222718e-154 CTL_MUT
## Mical1 2.370839e-157 15.5022227 0.222 0.009 7.112518e-154 CTL_MUT
## Elmo1 6.132534e-157 -0.5244622 0.360 0.311 1.839760e-153 CTL_MUT
## Helz2 1.100510e-156 -4.4600479 0.121 0.003 3.301529e-153 CTL_MUT
## Apoc3 7.184867e-156 1.6327079 0.147 0.002 2.155460e-152 CTL_MUT
## Pm20d1 7.738734e-156 1.5971380 0.146 0.003 2.321620e-152 CTL_MUT
## Cemip 9.588720e-156 -15.1705896 0.177 0.071 2.876616e-152 CTL_MUT
## Ntn1 2.218143e-154 -2.7326118 0.188 0.011 6.654429e-151 CTL_MUT
## Nkain2 3.733728e-154 -1.5571364 0.490 0.380 1.120118e-150 CTL_MUT
## Diaph3 7.330318e-153 -2.7222271 0.187 0.035 2.199095e-149 CTL_MUT
## Polr3e 9.674541e-152 -8.5189688 0.205 0.094 2.902362e-148 CTL_MUT
## Tbx2 2.223466e-151 0.8065017 0.103 0.002 6.670397e-148 CTL_MUT
## Map7 4.387933e-151 0.5428202 0.339 0.291 1.316380e-147 CTL_MUT
## Frrs1 5.087851e-151 6.2910797 0.168 0.017 1.526355e-147 CTL_MUT
## Nusap1 1.008109e-150 1.3126961 0.152 0.016 3.024326e-147 CTL_MUT
## Mpzl1 2.713192e-150 3.6506732 0.160 0.059 8.139575e-147 CTL_MUT
## Abca2 7.015902e-150 -0.7943389 0.192 0.148 2.104771e-146 CTL_MUT
## Tnfaip3 3.531613e-149 2.8065609 0.168 0.011 1.059484e-145 CTL_MUT
## Tagln2 1.191671e-148 -10.7331616 0.144 0.023 3.575012e-145 CTL_MUT
## Grm3 2.451135e-148 -0.6758810 0.378 0.342 7.353406e-145 CTL_MUT
## Slfn2 2.668416e-148 -0.9415616 0.104 0.002 8.005249e-145 CTL_MUT
## Slc25a18 4.506161e-148 -0.5957029 0.214 0.064 1.351848e-144 CTL_MUT
## Slc16a1 8.390551e-148 11.5503230 0.199 0.032 2.517165e-144 CTL_MUT
## Mast4 2.050420e-147 -2.5752494 0.459 0.411 6.151259e-144 CTL_MUT
## E130308A19Rik 2.320329e-147 -2.7777155 0.229 0.108 6.960986e-144 CTL_MUT
## Hck 4.805150e-147 -7.9004285 0.198 0.021 1.441545e-143 CTL_MUT
## Sp140 7.620202e-147 2.3721641 0.156 0.003 2.286061e-143 CTL_MUT
## Ankrd44 1.842181e-146 -6.4369586 0.186 0.094 5.526542e-143 CTL_MUT
## Wscd1 2.156979e-146 -1.5679389 0.174 0.067 6.470936e-143 CTL_MUT
## Aldh1l1 3.372665e-146 -4.5302134 0.177 0.075 1.011800e-142 CTL_MUT
## Man1a 3.881615e-146 0.3726439 0.226 0.182 1.164484e-142 CTL_MUT
## Dusp1 2.025292e-145 1.4669647 0.176 0.094 6.075875e-142 CTL_MUT
## Cdc37l1 2.562686e-145 -0.3896048 0.347 0.295 7.688059e-142 CTL_MUT
## Ezh2 2.978209e-145 -14.0860664 0.191 0.084 8.934627e-142 CTL_MUT
## Rnd2 5.534569e-145 -8.0729612 0.169 0.073 1.660371e-141 CTL_MUT
## Myo3b 1.487266e-144 0.6674739 0.197 0.007 4.461799e-141 CTL_MUT
## Kif13a 2.667412e-144 -1.5086190 0.207 0.105 8.002236e-141 CTL_MUT
## Ptgs2 3.043689e-144 -0.7236534 0.192 0.020 9.131067e-141 CTL_MUT
## Ccl17 3.903287e-144 6.3329580 0.242 0.013 1.170986e-140 CTL_MUT
## 4930544I03Rik 9.686446e-144 -2.3023845 0.182 0.017 2.905934e-140 CTL_MUT
## Kif26b 1.452486e-143 2.4001243 0.185 0.061 4.357457e-140 CTL_MUT
## Fnbp1 2.960140e-143 -0.2531983 0.289 0.228 8.880419e-140 CTL_MUT
## Adap2 4.033400e-143 -1.7505613 0.101 0.048 1.210020e-139 CTL_MUT
## Abcg2 1.338555e-142 -6.3480007 0.146 0.080 4.015666e-139 CTL_MUT
## Col1a2 4.372277e-142 -3.4932803 0.149 0.026 1.311683e-138 CTL_MUT
## Gm15417 1.038968e-141 -3.1657026 0.207 0.052 3.116905e-138 CTL_MUT
## 2010013B24Rik 2.257109e-141 -4.0750149 0.107 0.004 6.771326e-138 CTL_MUT
## Gm36908 7.502324e-141 -1.4935131 0.120 0.002 2.250697e-137 CTL_MUT
## Frmd4b 1.440078e-140 -2.9534271 0.219 0.123 4.320234e-137 CTL_MUT
## Lamp1 2.090203e-140 -0.9035303 0.378 0.360 6.270609e-137 CTL_MUT
## Mfge8 2.333500e-140 -0.4966117 0.185 0.169 7.000501e-137 CTL_MUT
## Thrsp 2.354944e-140 12.4472259 0.170 0.071 7.064833e-137 CTL_MUT
## Gm42997 6.513083e-140 -4.8398894 0.180 0.009 1.953925e-136 CTL_MUT
## Pappa 1.184903e-138 -2.7401865 0.150 0.004 3.554709e-135 CTL_MUT
## Pzp 9.949433e-138 -2.9735190 0.270 0.005 2.984830e-134 CTL_MUT
## Kndc1 1.467588e-137 0.2952058 0.182 0.116 4.402763e-134 CTL_MUT
## Enox1 3.013065e-137 -2.4765149 0.405 0.350 9.039194e-134 CTL_MUT
## Zcchc24 4.568022e-137 1.9820676 0.183 0.075 1.370407e-133 CTL_MUT
## Ppp2r3a 4.742658e-137 -2.3846704 0.294 0.236 1.422798e-133 CTL_MUT
## Tpm4 6.088442e-137 -10.1804289 0.147 0.056 1.826532e-133 CTL_MUT
## Ranbp1 6.944617e-137 2.6513295 0.215 0.214 2.083385e-133 CTL_MUT
## Srgap1 9.065543e-137 -2.3047010 0.171 0.084 2.719663e-133 CTL_MUT
## Gm47710 1.008392e-136 -4.7210020 0.131 0.005 3.025175e-133 CTL_MUT
## Rin2 3.321637e-136 -1.5476641 0.194 0.077 9.964911e-133 CTL_MUT
## Efhc1 3.846757e-136 -1.2998230 0.216 0.011 1.154027e-132 CTL_MUT
## Reep3 6.442641e-136 -1.5496918 0.259 0.179 1.932792e-132 CTL_MUT
## Emp3 4.451037e-135 -0.5713293 0.204 0.010 1.335311e-131 CTL_MUT
## Eci2 1.527157e-134 -2.9358393 0.181 0.075 4.581472e-131 CTL_MUT
## Spef2 1.902777e-134 -1.7614799 0.228 0.008 5.708330e-131 CTL_MUT
## Mpeg1 4.013481e-134 2.3403069 0.155 0.014 1.204044e-130 CTL_MUT
## Kcna1 1.018261e-133 -0.3093446 0.254 0.198 3.054782e-130 CTL_MUT
## Plce1 3.135616e-133 8.3086589 0.163 0.047 9.406848e-130 CTL_MUT
## Nr2f2 1.197101e-132 2.8241896 0.111 0.030 3.591303e-129 CTL_MUT
## Rgs12 2.024384e-132 -1.8846558 0.117 0.072 6.073151e-129 CTL_MUT
## Lyn 7.583878e-132 1.9057799 0.178 0.099 2.275163e-128 CTL_MUT
## Tie1 8.526353e-132 -3.6693448 0.172 0.008 2.557906e-128 CTL_MUT
## Ndnf 1.534384e-130 -6.3694020 0.119 0.025 4.603152e-127 CTL_MUT
## Egr1 1.864245e-130 3.4172935 0.221 0.304 5.592736e-127 CTL_MUT
## Ahnak 2.645239e-130 -0.4982986 0.109 0.057 7.935717e-127 CTL_MUT
## Erbb4 9.182542e-130 1.9610915 0.262 0.211 2.754763e-126 CTL_MUT
## Lama2 1.041694e-129 -4.4992547 0.174 0.102 3.125081e-126 CTL_MUT
## Tox3 1.233046e-129 0.8128160 0.171 0.089 3.699139e-126 CTL_MUT
## Zic4 1.424085e-129 -2.4911056 0.192 0.010 4.272255e-126 CTL_MUT
## Zfp36l1 2.518767e-129 3.4653658 0.169 0.097 7.556301e-126 CTL_MUT
## Slc27a1 8.048553e-129 -0.7307900 0.159 0.090 2.414566e-125 CTL_MUT
## Ctsz 8.522966e-129 -2.5637252 0.164 0.065 2.556890e-125 CTL_MUT
## Nfia 8.946433e-129 -1.1326622 0.410 0.387 2.683930e-125 CTL_MUT
## Id3 9.609951e-129 5.1280777 0.164 0.109 2.882985e-125 CTL_MUT
## Robo4 1.050243e-128 -3.3238639 0.159 0.008 3.150729e-125 CTL_MUT
## Igf1r 1.368095e-128 -0.9888569 0.384 0.377 4.104284e-125 CTL_MUT
## Tma16 5.974846e-128 -5.4587456 0.146 0.067 1.792454e-124 CTL_MUT
## Lonrf3 8.724556e-128 4.0411770 0.190 0.021 2.617367e-124 CTL_MUT
## Plin2 2.242814e-127 -1.1077686 0.204 0.011 6.728442e-124 CTL_MUT
## Unc5c 1.595307e-126 -3.7558341 0.383 0.332 4.785922e-123 CTL_MUT
## Prom1 2.228796e-126 -4.6319129 0.147 0.058 6.686388e-123 CTL_MUT
## Ggta1 2.408845e-126 -0.9146506 0.129 0.006 7.226536e-123 CTL_MUT
## Myoc 3.034241e-126 -0.3342814 0.154 0.012 9.102724e-123 CTL_MUT
## 2310039L15Rik 3.039209e-126 -1.1482492 0.119 0.006 9.117627e-123 CTL_MUT
## Chn2 7.348705e-126 6.9558499 0.230 0.203 2.204611e-122 CTL_MUT
## Crot 3.420647e-125 -4.5909042 0.184 0.086 1.026194e-121 CTL_MUT
## Gm765 9.397733e-125 -1.6236033 0.162 0.004 2.819320e-121 CTL_MUT
## Lmod1 1.462920e-124 4.3502779 0.172 0.003 4.388759e-121 CTL_MUT
## Rasgef1b 2.237641e-124 -0.3483141 0.336 0.293 6.712924e-121 CTL_MUT
## Dscaml1 3.059726e-124 -1.2551882 0.353 0.265 9.179178e-121 CTL_MUT
## Erg 3.291493e-124 1.3542882 0.161 0.020 9.874479e-121 CTL_MUT
## Frmd5 3.981724e-124 -1.5747572 0.423 0.381 1.194517e-120 CTL_MUT
## Jun 1.173095e-123 -2.5226431 0.233 0.161 3.519286e-120 CTL_MUT
## Ccnd2 1.903847e-123 -1.0122523 0.200 0.252 5.711540e-120 CTL_MUT
## Limch1 3.081921e-123 -1.9786828 0.343 0.299 9.245762e-120 CTL_MUT
## Hs3st3b1 4.748231e-123 4.7650574 0.129 0.003 1.424469e-119 CTL_MUT
## Gm49171 6.046186e-123 -5.5645398 0.188 0.023 1.813856e-119 CTL_MUT
## S1pr2 1.603962e-122 -2.1313677 0.116 0.002 4.811886e-119 CTL_MUT
## Pllp 1.717671e-122 -4.8632971 0.176 0.075 5.153014e-119 CTL_MUT
## Sox9 2.035409e-122 1.2798206 0.154 0.096 6.106226e-119 CTL_MUT
## Kcnj10 2.099219e-122 -0.7369657 0.190 0.104 6.297656e-119 CTL_MUT
## Eng 3.342419e-122 -4.5809531 0.113 0.034 1.002726e-118 CTL_MUT
## Hs3st3a1 4.247363e-122 0.5134114 0.208 0.008 1.274209e-118 CTL_MUT
## Gpr146 6.912171e-122 0.3170574 0.186 0.040 2.073651e-118 CTL_MUT
## Pdyn 2.162471e-121 -6.1968304 0.199 0.013 6.487412e-118 CTL_MUT
## Rarres2 2.306715e-121 -2.8544418 0.209 0.017 6.920144e-118 CTL_MUT
## Pipox 2.796321e-121 -6.7581224 0.133 0.002 8.388962e-118 CTL_MUT
## Tnfaip6 3.135923e-121 -5.8752468 0.159 0.050 9.407769e-118 CTL_MUT
## Vim 9.775128e-121 -2.8370117 0.149 0.045 2.932538e-117 CTL_MUT
## Gm20528 5.617851e-120 -3.2639228 0.103 0.004 1.685355e-116 CTL_MUT
## Rxfp1 1.145944e-119 1.0809646 0.176 0.044 3.437832e-116 CTL_MUT
## A330048O09Rik 1.329532e-119 12.2672691 0.270 0.009 3.988595e-116 CTL_MUT
## Antxr2 3.088575e-119 -10.4872422 0.232 0.012 9.265726e-116 CTL_MUT
## Arhgap4 3.511595e-119 -7.6389558 0.232 0.009 1.053478e-115 CTL_MUT
## Enpp2 3.519042e-119 0.4567447 0.349 0.310 1.055713e-115 CTL_MUT
## Grb14 3.876330e-119 -1.9138647 0.272 0.211 1.162899e-115 CTL_MUT
## Myl9 1.465498e-118 -1.1258892 0.114 0.020 4.396495e-115 CTL_MUT
## Ampd3 1.538445e-118 0.5844402 0.183 0.050 4.615335e-115 CTL_MUT
## Litaf 1.794603e-118 -2.0248381 0.184 0.046 5.383810e-115 CTL_MUT
## Sytl2 2.152695e-118 6.1025662 0.202 0.132 6.458086e-115 CTL_MUT
## Phyhipl 6.548293e-118 3.0171809 0.258 0.260 1.964488e-114 CTL_MUT
## Zfp521 8.203789e-118 -4.3496502 0.172 0.042 2.461137e-114 CTL_MUT
## St6gal1 2.159405e-117 -0.3486832 0.212 0.083 6.478215e-114 CTL_MUT
## 5430427M07Rik 4.351505e-117 7.2361410 0.233 0.004 1.305451e-113 CTL_MUT
## Maml3 5.221094e-117 0.5706550 0.257 0.203 1.566328e-113 CTL_MUT
## Serinc5 7.128502e-117 -0.5404857 0.220 0.126 2.138551e-113 CTL_MUT
## Cpm 7.263973e-117 -7.4692400 0.159 0.033 2.179192e-113 CTL_MUT
## 4931415C17Rik 1.807575e-116 -5.9283511 0.242 0.008 5.422726e-113 CTL_MUT
## 1190005I06Rik 3.520081e-116 9.5225130 0.210 0.060 1.056024e-112 CTL_MUT
## Onecut2 4.049172e-116 -3.7508632 0.202 0.024 1.214751e-112 CTL_MUT
## Csf1 2.014605e-115 4.5958763 0.203 0.032 6.043814e-112 CTL_MUT
## 4930445E18Rik 4.762820e-115 -6.1341173 0.199 0.008 1.428846e-111 CTL_MUT
## Scube1 9.157301e-115 7.8228409 0.163 0.073 2.747190e-111 CTL_MUT
## Tmtc2 1.029842e-114 -2.2993910 0.274 0.219 3.089527e-111 CTL_MUT
## Sema6d 1.622781e-114 -1.6075697 0.375 0.315 4.868343e-111 CTL_MUT
## Gramd3 1.688302e-114 0.7813816 0.162 0.053 5.064907e-111 CTL_MUT
## Shroom4 2.099756e-114 -2.0985045 0.202 0.023 6.299267e-111 CTL_MUT
## Nkx2-2os 2.103681e-114 -2.9106490 0.203 0.016 6.311042e-111 CTL_MUT
## Elovl1 2.271895e-114 1.2431490 0.199 0.040 6.815686e-111 CTL_MUT
## Gpr17 4.654660e-114 -2.5528765 0.126 0.030 1.396398e-110 CTL_MUT
## A330033J07Rik 6.442013e-114 -0.6530719 0.109 0.002 1.932604e-110 CTL_MUT
## Neat1 1.007625e-113 -3.4212369 0.165 0.073 3.022875e-110 CTL_MUT
## Fam163a 2.127355e-113 8.1307304 0.174 0.016 6.382064e-110 CTL_MUT
## Rcbtb1 2.807920e-113 -3.8044625 0.205 0.076 8.423761e-110 CTL_MUT
## Bag3 2.940016e-113 -0.5392440 0.243 0.008 8.820049e-110 CTL_MUT
## Bmp2k 3.064735e-113 5.1752284 0.167 0.070 9.194204e-110 CTL_MUT
## Fgf1 3.565928e-113 1.3653794 0.212 0.084 1.069779e-109 CTL_MUT
## Bard1 5.261441e-113 -1.4335896 0.104 0.002 1.578432e-109 CTL_MUT
## Gm49313 5.727208e-113 -1.3901665 0.219 0.004 1.718162e-109 CTL_MUT
## Secisbp2l 1.613209e-112 -4.7773642 0.248 0.213 4.839627e-109 CTL_MUT
## Aebp1 2.009423e-112 1.5009449 0.184 0.014 6.028268e-109 CTL_MUT
## Rrbp1 9.600642e-112 3.1635069 0.207 0.158 2.880193e-108 CTL_MUT
## Mrc1 2.343504e-111 -1.6318644 0.128 0.009 7.030513e-108 CTL_MUT
## Jcad 9.550532e-111 -1.6938544 0.178 0.114 2.865160e-107 CTL_MUT
## Tsc22d4 1.429437e-110 -1.9498001 0.330 0.262 4.288312e-107 CTL_MUT
## Cdkn1a 2.514928e-110 4.2216324 0.208 0.159 7.544784e-107 CTL_MUT
## Gm20713 5.008532e-110 -7.4071464 0.144 0.071 1.502560e-106 CTL_MUT
## Pdgfa 9.902578e-110 0.4582530 0.174 0.113 2.970773e-106 CTL_MUT
## Ism1 2.044579e-109 -10.3619805 0.184 0.028 6.133737e-106 CTL_MUT
## Slc15a3 8.614009e-109 -3.9874961 0.138 0.012 2.584203e-105 CTL_MUT
## Tac1 1.461352e-108 -1.0512276 0.134 0.026 4.384056e-105 CTL_MUT
## Zic1 6.306078e-108 4.9296093 0.177 0.023 1.891823e-104 CTL_MUT
## Rlbp1 1.545596e-107 0.6922578 0.235 0.022 4.636787e-104 CTL_MUT
## Pdlim5 3.249855e-107 8.2997095 0.189 0.066 9.749564e-104 CTL_MUT
## Tnf 3.465967e-107 -3.3445292 0.100 0.004 1.039790e-103 CTL_MUT
## Cavin1 4.975086e-107 -1.9225823 0.156 0.012 1.492526e-103 CTL_MUT
## Tgif2 5.515685e-107 -3.5715866 0.120 0.003 1.654705e-103 CTL_MUT
## Mlc1 6.541058e-107 0.4135639 0.205 0.101 1.962317e-103 CTL_MUT
## Rras2 7.016291e-107 10.4120718 0.195 0.103 2.104887e-103 CTL_MUT
## Dock10 9.246717e-107 -4.7196436 0.238 0.154 2.774015e-103 CTL_MUT
## Mfsd2a 9.898346e-107 1.0821564 0.151 0.106 2.969504e-103 CTL_MUT
## Pdgfrl 1.106730e-106 10.5780581 0.206 0.005 3.320189e-103 CTL_MUT
## Dnah14 1.116386e-106 5.3753612 0.175 0.033 3.349159e-103 CTL_MUT
## Fzd6 4.124952e-106 1.7031542 0.149 0.021 1.237486e-102 CTL_MUT
## Serpine1 4.410602e-106 -2.4885467 0.115 0.005 1.323180e-102 CTL_MUT
## Ccn1 6.507257e-106 -7.4655367 0.203 0.019 1.952177e-102 CTL_MUT
## Chst2 1.325211e-105 1.1615415 0.196 0.151 3.975633e-102 CTL_MUT
## Gm28411 2.909508e-105 -1.8966398 0.113 0.002 8.728523e-102 CTL_MUT
## Sema6a 6.848053e-105 -4.9469182 0.209 0.129 2.054416e-101 CTL_MUT
## Hopx 4.819824e-104 4.0442509 0.193 0.069 1.445947e-100 CTL_MUT
## Tcn2 7.516917e-104 -7.7914825 0.179 0.033 2.255075e-100 CTL_MUT
## Sox1ot 1.931886e-103 -10.5745004 0.170 0.018 5.795659e-100 CTL_MUT
## Pilra 2.259859e-103 -1.2276876 0.102 0.002 6.779577e-100 CTL_MUT
## 4921511C10Rik 3.112175e-103 -0.3578668 0.192 0.082 9.336526e-100 CTL_MUT
## Cyp26b1 4.329341e-103 -1.1330530 0.258 0.007 1.298802e-99 CTL_MUT
## Cyp2j6 5.257542e-103 3.5710047 0.195 0.046 1.577262e-99 CTL_MUT
## Fes 5.994894e-103 5.5074600 0.145 0.004 1.798468e-99 CTL_MUT
## Lrp1b 1.549729e-102 -2.0505669 0.478 0.393 4.649187e-99 CTL_MUT
## Plppr1 3.002249e-102 3.5424313 0.179 0.076 9.006746e-99 CTL_MUT
## AI182371 4.686655e-102 -0.5916354 0.110 0.002 1.405996e-98 CTL_MUT
## Espn 4.948404e-102 7.9411610 0.159 0.004 1.484521e-98 CTL_MUT
## Slc38a2 7.582725e-102 -5.4188796 0.222 0.211 2.274818e-98 CTL_MUT
## Adora2a 3.762702e-101 -1.4245392 0.104 0.002 1.128811e-97 CTL_MUT
## Gli3 4.979342e-101 -10.7840809 0.136 0.067 1.493803e-97 CTL_MUT
## Gm16168 5.843331e-101 2.7302081 0.194 0.071 1.752999e-97 CTL_MUT
## Myh11 8.641355e-101 -1.1468117 0.139 0.007 2.592406e-97 CTL_MUT
## Fgfr3 8.979466e-101 1.3633968 0.166 0.100 2.693840e-97 CTL_MUT
## Gch1 1.131411e-100 -0.7796342 0.110 0.009 3.394232e-97 CTL_MUT
## Palmd 1.276291e-100 3.0973049 0.140 0.097 3.828874e-97 CTL_MUT
## Cntn2 2.205983e-100 -2.9167990 0.192 0.065 6.617950e-97 CTL_MUT
## Bdnf 2.684746e-100 -2.3508227 0.127 0.105 8.054238e-97 CTL_MUT
## Vsir 6.743029e-100 -5.1794851 0.101 0.039 2.022909e-96 CTL_MUT
## Smtn 8.770675e-100 0.7066439 0.202 0.010 2.631202e-96 CTL_MUT
## Fmo1 1.344014e-99 -1.2495702 0.189 0.019 4.032042e-96 CTL_MUT
## 1700094D03Rik 2.071100e-99 -2.5609801 0.244 0.013 6.213300e-96 CTL_MUT
## Apoh 3.191152e-99 -3.4390412 0.157 0.002 9.573457e-96 CTL_MUT
## Calm1 5.180170e-99 -0.3428228 0.313 0.407 1.554051e-95 CTL_MUT
## Akap12 3.451423e-98 -1.3884379 0.163 0.046 1.035427e-94 CTL_MUT
## Rtp4 4.430260e-98 -9.1557903 0.206 0.014 1.329078e-94 CTL_MUT
## Tlr13 6.498656e-98 -4.5700704 0.114 0.004 1.949597e-94 CTL_MUT
## Adamts19 7.228068e-98 -0.9951872 0.114 0.003 2.168420e-94 CTL_MUT
## Tnfrsf13b 1.390273e-97 -4.8593616 0.112 0.004 4.170818e-94 CTL_MUT
## Neb 4.050040e-97 0.6126903 0.238 0.008 1.215012e-93 CTL_MUT
## Rest 8.496306e-97 -0.9025316 0.212 0.014 2.548892e-93 CTL_MUT
## Sh3d19 1.253270e-96 -3.9133723 0.205 0.113 3.759810e-93 CTL_MUT
## Gm26691 1.326984e-96 0.5861082 0.227 0.117 3.980951e-93 CTL_MUT
## Ocln 2.313493e-96 -6.1558149 0.147 0.015 6.940480e-93 CTL_MUT
## Gm42303 2.455861e-96 -2.3054489 0.197 0.077 7.367584e-93 CTL_MUT
## Smyd3 2.697824e-96 -0.4437830 0.361 0.323 8.093471e-93 CTL_MUT
## Ano4 3.456081e-96 -2.5486350 0.330 0.206 1.036824e-92 CTL_MUT
## Gm43376 1.225158e-95 -1.6509756 0.215 0.067 3.675474e-92 CTL_MUT
## Mylk 1.466286e-95 -3.0594237 0.157 0.022 4.398857e-92 CTL_MUT
## Naaladl2 1.772575e-95 -0.7910500 0.352 0.277 5.317725e-92 CTL_MUT
## Dleu2 3.076038e-95 -4.6950212 0.243 0.202 9.228115e-92 CTL_MUT
## Samd5 6.289237e-95 6.2547714 0.191 0.080 1.886771e-91 CTL_MUT
## Alpk1 1.259479e-94 4.5668630 0.180 0.023 3.778436e-91 CTL_MUT
## Gm45083 1.327843e-94 -2.0103818 0.153 0.008 3.983528e-91 CTL_MUT
## Ptpn14 3.369078e-94 -12.6289601 0.177 0.017 1.010723e-90 CTL_MUT
## Rtkn2 4.350714e-94 2.5091820 0.201 0.022 1.305214e-90 CTL_MUT
## F830045P16Rik 5.337665e-94 -4.9303639 0.130 0.004 1.601299e-90 CTL_MUT
## Tmem173 6.514401e-94 -1.5732310 0.124 0.006 1.954320e-90 CTL_MUT
## Etv1 6.763099e-94 -5.0208802 0.219 0.174 2.028930e-90 CTL_MUT
## Abcc6 5.007770e-93 -1.5030958 0.114 0.002 1.502331e-89 CTL_MUT
## Dner 9.135791e-93 -5.3707236 0.255 0.208 2.740737e-89 CTL_MUT
## Gm14964 9.363555e-93 -6.5641299 0.190 0.016 2.809067e-89 CTL_MUT
## 2310014F06Rik 1.782919e-92 5.2921588 0.221 0.014 5.348757e-89 CTL_MUT
## Sirt2 1.801431e-92 -0.9937319 0.271 0.214 5.404294e-89 CTL_MUT
## Gm45321 2.661381e-92 -3.2530512 0.101 0.006 7.984143e-89 CTL_MUT
## Fzd2 3.970256e-92 -2.1777346 0.166 0.055 1.191077e-88 CTL_MUT
## Mcm5 4.235289e-92 -1.8148109 0.191 0.006 1.270587e-88 CTL_MUT
## Gm38576 5.269816e-92 -3.2027962 0.120 0.003 1.580945e-88 CTL_MUT
## Scara3 1.186740e-91 -2.7537919 0.178 0.029 3.560220e-88 CTL_MUT
## Zfp36 1.592843e-91 0.7976012 0.152 0.030 4.778529e-88 CTL_MUT
## Gm19935 2.066190e-91 1.4576517 0.115 0.003 6.198569e-88 CTL_MUT
## Ankfn1 2.355289e-91 0.4020452 0.185 0.031 7.065866e-88 CTL_MUT
## Cass4 3.320544e-91 -1.2201820 0.137 0.004 9.961632e-88 CTL_MUT
## Crybg1 9.504733e-91 4.0490755 0.162 0.003 2.851420e-87 CTL_MUT
## Cd63 2.194320e-90 -1.4235959 0.226 0.155 6.582959e-87 CTL_MUT
## Dcc 2.748037e-90 -11.0216959 0.387 0.352 8.244112e-87 CTL_MUT
## Chst9 3.009513e-90 -3.6485381 0.213 0.019 9.028538e-87 CTL_MUT
## Tmem178 3.497572e-90 -1.5259294 0.269 0.240 1.049272e-86 CTL_MUT
## Gm41414 4.802217e-90 -2.0720021 0.106 0.006 1.440665e-86 CTL_MUT
## Grip1os2 6.931146e-90 -3.9007401 0.119 0.019 2.079344e-86 CTL_MUT
## Tmem163 7.384443e-90 3.5453798 0.184 0.065 2.215333e-86 CTL_MUT
## Aspg 1.378652e-89 0.9513356 0.144 0.003 4.135956e-86 CTL_MUT
## Slc5a4b 1.856249e-89 -3.7439959 0.196 0.005 5.568748e-86 CTL_MUT
## Cryab 3.350428e-89 -5.4306243 0.277 0.215 1.005128e-85 CTL_MUT
## Calm2 3.711810e-89 0.3794488 0.290 0.388 1.113543e-85 CTL_MUT
## Bub1b 4.268026e-89 -9.8334455 0.136 0.006 1.280408e-85 CTL_MUT
## Cstb 5.429856e-89 2.9165706 0.188 0.117 1.628957e-85 CTL_MUT
## Tmem141 5.448236e-89 -4.6146643 0.179 0.068 1.634471e-85 CTL_MUT
## Itpr2 7.729968e-89 -8.2198462 0.177 0.115 2.318990e-85 CTL_MUT
## Sox4 8.477970e-89 -5.5415972 0.182 0.125 2.543391e-85 CTL_MUT
## Gm42047 1.332220e-88 -1.6621249 0.121 0.006 3.996660e-85 CTL_MUT
## Egfl7 4.700629e-88 -14.4513134 0.126 0.078 1.410189e-84 CTL_MUT
## Gm12239 8.334232e-88 -1.7184086 0.221 0.010 2.500270e-84 CTL_MUT
## Arhgap31 2.613868e-87 1.5250238 0.171 0.100 7.841603e-84 CTL_MUT
## Cd1d1 2.811481e-87 -1.6283827 0.104 0.002 8.434444e-84 CTL_MUT
## Gm29481 2.813771e-87 -0.2829656 0.111 0.002 8.441312e-84 CTL_MUT
## Fxyd1 3.568861e-87 -2.5064869 0.170 0.145 1.070658e-83 CTL_MUT
## A330015K06Rik 5.629559e-87 4.1540142 0.193 0.077 1.688868e-83 CTL_MUT
## Lrmda 8.682044e-87 1.9080543 0.151 0.067 2.604613e-83 CTL_MUT
## Sdc4 1.129158e-86 -1.4550543 0.165 0.102 3.387474e-83 CTL_MUT
## Gm26510 1.296168e-86 1.0145762 0.112 0.004 3.888505e-83 CTL_MUT
## Slc37a2 1.850867e-86 -0.4460387 0.178 0.008 5.552601e-83 CTL_MUT
## Erbin 2.606812e-86 -0.6171629 0.224 0.122 7.820436e-83 CTL_MUT
## Cdkn1c 3.439524e-86 -11.8004769 0.201 0.015 1.031857e-82 CTL_MUT
## Apcdd1 3.752737e-86 5.7312988 0.149 0.033 1.125821e-82 CTL_MUT
## Nrgn 4.310744e-86 5.6588307 0.217 0.321 1.293223e-82 CTL_MUT
## Cdh19 5.323239e-86 -2.9036835 0.182 0.090 1.596972e-82 CTL_MUT
## Slc9a3r1 8.683023e-86 -4.2210356 0.189 0.047 2.604907e-82 CTL_MUT
## AC150683.1 1.135499e-85 -1.5991591 0.220 0.007 3.406496e-82 CTL_MUT
## Mkx 2.113698e-85 0.9189934 0.215 0.181 6.341094e-82 CTL_MUT
## Gpr176 2.277104e-85 -5.2107488 0.170 0.034 6.831312e-82 CTL_MUT
## Sept4 5.915071e-85 -5.5074020 0.222 0.165 1.774521e-81 CTL_MUT
## Nfkbid 1.284386e-84 0.9088000 0.151 0.015 3.853159e-81 CTL_MUT
## Rep15 1.934562e-84 -10.2085073 0.224 0.008 5.803686e-81 CTL_MUT
## Gm15680 2.712475e-84 -0.9980128 0.189 0.027 8.137426e-81 CTL_MUT
## Astn2 2.882858e-84 -0.5991214 0.375 0.353 8.648575e-81 CTL_MUT
## Lrrtm3 3.297197e-84 -0.4288865 0.407 0.362 9.891591e-81 CTL_MUT
## Zfpm2 3.452703e-84 -10.9304915 0.293 0.241 1.035811e-80 CTL_MUT
## Car5a 6.659048e-84 1.4458010 0.102 0.004 1.997714e-80 CTL_MUT
## Exo1 1.139420e-83 -4.2147851 0.126 0.004 3.418259e-80 CTL_MUT
## Acsl3 1.687596e-83 -1.4499480 0.312 0.314 5.062788e-80 CTL_MUT
## Gatm 4.206874e-83 -1.0273845 0.226 0.135 1.262062e-79 CTL_MUT
## Slc13a4 5.056186e-83 2.1317849 0.107 0.005 1.516856e-79 CTL_MUT
## Myorg 5.690286e-83 0.7798825 0.208 0.027 1.707086e-79 CTL_MUT
## Ptprg 7.614015e-83 -1.6075735 0.419 0.390 2.284205e-79 CTL_MUT
## Gm45708 9.946928e-83 -6.5968137 0.180 0.013 2.984078e-79 CTL_MUT
## Sgms1 1.332618e-82 -3.2720011 0.268 0.235 3.997855e-79 CTL_MUT
## Gm35188 1.347959e-82 -4.1633040 0.193 0.122 4.043877e-79 CTL_MUT
## Rnf125 1.348888e-82 -5.9950481 0.119 0.004 4.046664e-79 CTL_MUT
## Loxl2 1.561952e-82 -4.2948609 0.124 0.003 4.685855e-79 CTL_MUT
## Sorcs1 1.992879e-82 -5.7877115 0.368 0.304 5.978638e-79 CTL_MUT
## Cdc42ep2 2.298952e-82 4.0731116 0.164 0.030 6.896857e-79 CTL_MUT
## Rnf144b 3.694337e-82 -1.1907547 0.164 0.050 1.108301e-78 CTL_MUT
## Arpc1a 1.008554e-81 -1.8572522 0.325 0.319 3.025661e-78 CTL_MUT
## Prkn 1.179224e-81 -4.5960234 0.440 0.387 3.537673e-78 CTL_MUT
## Tmcc3 1.546249e-81 -1.8633722 0.221 0.139 4.638746e-78 CTL_MUT
## Lncpint 1.574142e-81 -0.2607448 0.426 0.385 4.722425e-78 CTL_MUT
## Map4k4 3.336792e-81 2.1354279 0.309 0.260 1.001038e-77 CTL_MUT
## Olfm1 4.572385e-81 -0.4455237 0.315 0.389 1.371716e-77 CTL_MUT
## Fcgr3 5.197954e-81 12.0372810 0.111 0.027 1.559386e-77 CTL_MUT
## Tmem140 8.298962e-81 -3.2850225 0.110 0.006 2.489689e-77 CTL_MUT
## Atad2 8.354179e-81 2.9751040 0.175 0.038 2.506254e-77 CTL_MUT
## Gm6145 1.319346e-80 -1.9456477 0.126 0.071 3.958038e-77 CTL_MUT
## Magi2 1.430625e-80 -0.2572224 0.504 0.427 4.291875e-77 CTL_MUT
## Ezr 2.922009e-80 -1.6800962 0.177 0.088 8.766028e-77 CTL_MUT
## Uchl1 3.233620e-80 1.4650832 0.318 0.394 9.700861e-77 CTL_MUT
## Plin3 8.536941e-80 1.2732389 0.198 0.014 2.561082e-76 CTL_MUT
## Camk2n1 8.546166e-80 -0.7001165 0.321 0.393 2.563850e-76 CTL_MUT
## Wwtr1 9.177508e-80 -10.3873449 0.162 0.037 2.753252e-76 CTL_MUT
## Sh3gl3 2.587960e-79 -1.6641485 0.216 0.169 7.763880e-76 CTL_MUT
## Grid2 4.416260e-79 -2.9771466 0.431 0.391 1.324878e-75 CTL_MUT
## Myl4 5.417074e-79 -3.5328524 0.139 0.077 1.625122e-75 CTL_MUT
## Thsd1 5.796668e-79 -6.4012749 0.194 0.016 1.739000e-75 CTL_MUT
## Nfkbiz 7.615478e-79 4.0877490 0.217 0.024 2.284643e-75 CTL_MUT
## Rhog 8.926803e-79 -4.4409514 0.161 0.054 2.678041e-75 CTL_MUT
## Myo6 9.785119e-79 -1.8433721 0.276 0.218 2.935536e-75 CTL_MUT
## Nfib 1.369432e-78 -0.3252776 0.434 0.416 4.108296e-75 CTL_MUT
## Taldo1 8.054615e-78 -3.4905688 0.241 0.205 2.416384e-74 CTL_MUT
## Col25a1 2.584921e-77 -5.4670107 0.184 0.099 7.754762e-74 CTL_MUT
## Zfp536 3.202387e-77 -5.1954099 0.238 0.165 9.607161e-74 CTL_MUT
## Car4 4.042030e-77 -2.6696952 0.138 0.097 1.212609e-73 CTL_MUT
## Lypd6b 5.016464e-77 3.7686754 0.168 0.022 1.504939e-73 CTL_MUT
## Plekho2 6.361687e-77 -2.6139745 0.215 0.011 1.908506e-73 CTL_MUT
## Nebl 6.386822e-77 4.0921487 0.342 0.327 1.916047e-73 CTL_MUT
## Fam107b 8.325489e-77 -0.4169667 0.205 0.017 2.497647e-73 CTL_MUT
## H2afx 1.657792e-76 7.4080581 0.147 0.055 4.973377e-73 CTL_MUT
## mt-Nd6 2.428431e-76 -2.0455958 0.275 0.242 7.285294e-73 CTL_MUT
## Hcn1 3.158419e-76 -6.1358296 0.359 0.318 9.475256e-73 CTL_MUT
## Ctso 3.921218e-76 4.2817096 0.180 0.056 1.176365e-72 CTL_MUT
## Ncam2 3.966574e-76 4.4355975 0.433 0.388 1.189972e-72 CTL_MUT
## St3gal4 5.308262e-76 -10.5200576 0.162 0.080 1.592478e-72 CTL_MUT
## Gm16731 5.742479e-76 -1.6005434 0.117 0.002 1.722744e-72 CTL_MUT
## L3mbtl4 5.865387e-76 4.4971806 0.199 0.042 1.759616e-72 CTL_MUT
## Gm13889 9.329004e-76 1.9097900 0.185 0.052 2.798701e-72 CTL_MUT
## Barx2 9.856250e-76 8.1957936 0.170 0.020 2.956875e-72 CTL_MUT
## Flrt2 1.561044e-75 -1.1857519 0.349 0.330 4.683132e-72 CTL_MUT
## S100a16 2.005767e-75 -1.4599646 0.220 0.130 6.017300e-72 CTL_MUT
## Mdk 2.598854e-75 -5.9395813 0.155 0.050 7.796563e-72 CTL_MUT
## Daam2 3.685264e-75 0.2881931 0.184 0.104 1.105579e-71 CTL_MUT
## Atp6v0c 3.737255e-75 0.9612753 0.315 0.400 1.121176e-71 CTL_MUT
## Spaar 4.152555e-75 1.1620469 0.109 0.003 1.245766e-71 CTL_MUT
## Sp100 9.149215e-75 -3.2769435 0.127 0.005 2.744764e-71 CTL_MUT
## Vcl 9.204695e-75 1.5421726 0.171 0.091 2.761409e-71 CTL_MUT
## Ptpro 2.123121e-74 -6.4624216 0.164 0.059 6.369363e-71 CTL_MUT
## Gm16618 2.351217e-74 -2.7827462 0.235 0.006 7.053651e-71 CTL_MUT
## Fxyd7 2.980639e-74 1.7736659 0.227 0.314 8.941916e-71 CTL_MUT
## Qk 6.764391e-74 -0.5934972 0.367 0.311 2.029317e-70 CTL_MUT
## Sgk3 7.266827e-74 -1.8299270 0.213 0.127 2.180048e-70 CTL_MUT
## Prodh 2.790117e-73 -0.4339686 0.155 0.080 8.370352e-70 CTL_MUT
## Spc24 2.867811e-73 -1.5399144 0.159 0.008 8.603433e-70 CTL_MUT
## Arhgap24 3.942546e-73 -1.9311265 0.117 0.039 1.182764e-69 CTL_MUT
## Nav2 5.692838e-73 -5.5701307 0.443 0.406 1.707852e-69 CTL_MUT
## Gpc3 5.973173e-73 -0.5708156 0.158 0.011 1.791952e-69 CTL_MUT
## Zfp385b 7.827989e-73 -0.6783707 0.352 0.307 2.348397e-69 CTL_MUT
## Itih5 1.186326e-72 1.2669561 0.127 0.054 3.558977e-69 CTL_MUT
## Car2 1.526202e-72 -2.7804055 0.242 0.165 4.578605e-69 CTL_MUT
## Entpd1 1.768107e-72 -11.0635653 0.109 0.058 5.304321e-69 CTL_MUT
## Kirrel3 1.785159e-72 -4.8680094 0.356 0.320 5.355476e-69 CTL_MUT
## Eln 1.848141e-72 -8.0121154 0.211 0.011 5.544422e-69 CTL_MUT
## Gm13629 3.184401e-72 -9.5801181 0.186 0.031 9.553204e-69 CTL_MUT
## 2500002B13Rik 9.099552e-72 8.1974420 0.220 0.004 2.729866e-68 CTL_MUT
## Cavin2 1.500748e-71 -4.7014713 0.154 0.041 4.502243e-68 CTL_MUT
## Rtn1 2.661018e-71 0.6762238 0.313 0.398 7.983053e-68 CTL_MUT
## Tmem119 3.619244e-71 -6.9808716 0.103 0.037 1.085773e-67 CTL_MUT
## Trim34a 3.851785e-71 8.3490938 0.183 0.005 1.155535e-67 CTL_MUT
## Grin3a 3.959261e-71 -2.4873764 0.136 0.093 1.187778e-67 CTL_MUT
## Tenm3 4.247316e-71 0.3910948 0.332 0.317 1.274195e-67 CTL_MUT
## Tyrobp 5.579526e-71 -11.7782355 0.136 0.107 1.673858e-67 CTL_MUT
## C5ar2 6.540916e-71 6.2764425 0.103 0.003 1.962275e-67 CTL_MUT
## Dlx1as 6.604495e-71 -7.9653418 0.154 0.033 1.981349e-67 CTL_MUT
## Lgi3 7.499614e-71 -5.4573270 0.187 0.098 2.249884e-67 CTL_MUT
## Meis1 5.732696e-70 -1.3290409 0.214 0.028 1.719809e-66 CTL_MUT
## Foxd1 6.916546e-70 -0.9906939 0.102 0.004 2.074964e-66 CTL_MUT
## Mef2c 7.406818e-70 -0.5671541 0.335 0.412 2.222045e-66 CTL_MUT
## Edil3 8.050186e-70 -0.5797970 0.393 0.351 2.415056e-66 CTL_MUT
## Pex5l 1.283977e-69 -1.6262020 0.392 0.353 3.851931e-66 CTL_MUT
## Gsto1 1.554492e-69 -3.7648113 0.157 0.056 4.663475e-66 CTL_MUT
## Ntsr2 1.625823e-69 4.7577321 0.198 0.181 4.877470e-66 CTL_MUT
## Rgs5 1.652177e-69 -1.1104059 0.119 0.083 4.956531e-66 CTL_MUT
## Ccdc85a 2.559094e-69 -0.8868238 0.316 0.273 7.677282e-66 CTL_MUT
## Pard3b 4.550709e-69 -2.3778038 0.162 0.087 1.365213e-65 CTL_MUT
## Cbs 4.609406e-69 6.7456820 0.179 0.044 1.382822e-65 CTL_MUT
## Nos3 1.426383e-68 8.6243472 0.172 0.015 4.279150e-65 CTL_MUT
## Acsbg1 1.650633e-68 4.3415950 0.181 0.097 4.951898e-65 CTL_MUT
## Unc5b 1.916849e-68 -14.1102334 0.153 0.019 5.750548e-65 CTL_MUT
## Tlr4 3.515328e-68 -1.0845963 0.136 0.006 1.054599e-64 CTL_MUT
## Lmnb1 4.025443e-68 -7.8304795 0.163 0.033 1.207633e-64 CTL_MUT
## Ephb1 4.026085e-68 2.7306518 0.271 0.212 1.207825e-64 CTL_MUT
## Ccnd3 5.811521e-68 0.8322673 0.170 0.084 1.743456e-64 CTL_MUT
## Gm5089.1 6.915327e-68 3.9274131 0.153 0.004 2.074598e-64 CTL_MUT
## Abcc3 9.396971e-68 -4.0571325 0.104 0.004 2.819091e-64 CTL_MUT
## Timp4 1.114887e-67 0.6792621 0.189 0.094 3.344660e-64 CTL_MUT
## Sox5 1.496213e-67 -0.9963595 0.381 0.337 4.488639e-64 CTL_MUT
## Grid1 1.508613e-67 -0.5401557 0.393 0.348 4.525840e-64 CTL_MUT
## Rreb1 1.661870e-67 2.2444927 0.159 0.059 4.985611e-64 CTL_MUT
## Lims2 1.755442e-67 4.0104904 0.173 0.040 5.266325e-64 CTL_MUT
## Pon2 1.933502e-67 -3.3300496 0.218 0.093 5.800505e-64 CTL_MUT
## Stmn3 2.075501e-67 -0.4113674 0.312 0.382 6.226503e-64 CTL_MUT
## Plxna4 3.893766e-67 -0.7746049 0.357 0.340 1.168130e-63 CTL_MUT
## Magt1 5.160449e-67 5.6459239 0.179 0.060 1.548135e-63 CTL_MUT
## Wwox 5.787208e-67 -0.5967167 0.335 0.283 1.736163e-63 CTL_MUT
## Scd2 9.664430e-67 -0.9637855 0.413 0.408 2.899329e-63 CTL_MUT
## Lpp 1.016277e-66 -3.9212033 0.191 0.134 3.048832e-63 CTL_MUT
## Selenow 1.165411e-66 -0.3110637 0.346 0.422 3.496233e-63 CTL_MUT
## Gabrg3 1.613915e-66 -3.1157079 0.389 0.337 4.841744e-63 CTL_MUT
## Pdgfrb 2.352964e-66 -2.3650099 0.132 0.030 7.058893e-63 CTL_MUT
## Rasip1 2.390202e-66 -3.8802308 0.145 0.023 7.170605e-63 CTL_MUT
## Hif3a 2.738770e-66 -0.8848209 0.133 0.048 8.216311e-63 CTL_MUT
## Tek 2.795022e-66 -6.9715317 0.157 0.050 8.385067e-63 CTL_MUT
## Ust 3.643037e-66 -0.7116775 0.141 0.086 1.092911e-62 CTL_MUT
## Arhgef26 4.284026e-66 5.8726135 0.137 0.061 1.285208e-62 CTL_MUT
## Swap70 4.712032e-66 -5.3781496 0.176 0.025 1.413610e-62 CTL_MUT
## F13a1 5.875225e-66 -1.1155778 0.166 0.009 1.762567e-62 CTL_MUT
## Ier3 6.785569e-66 4.7554109 0.159 0.035 2.035671e-62 CTL_MUT
## Ap1s2 1.420807e-65 -4.2954636 0.155 0.064 4.262420e-62 CTL_MUT
## Synpo2 1.432031e-65 -3.9074377 0.176 0.017 4.296092e-62 CTL_MUT
## Cybb 2.762624e-65 -0.6702779 0.109 0.002 8.287872e-62 CTL_MUT
## Rapgef3 3.497146e-65 1.9870543 0.156 0.039 1.049144e-61 CTL_MUT
## Slc8a1 3.854292e-65 -0.7712087 0.453 0.412 1.156288e-61 CTL_MUT
## Tgfbi 4.220460e-65 -0.3933756 0.113 0.003 1.266138e-61 CTL_MUT
## Garnl3 5.448019e-65 -4.5430986 0.341 0.287 1.634406e-61 CTL_MUT
## Itpripl2 5.610123e-65 3.5819170 0.148 0.012 1.683037e-61 CTL_MUT
## Alkal2 5.903561e-65 -3.8444502 0.208 0.007 1.771068e-61 CTL_MUT
## Gm13905 7.122201e-65 -10.9290996 0.104 0.003 2.136660e-61 CTL_MUT
## Nat8f3 7.511718e-65 -0.7029512 0.182 0.009 2.253515e-61 CTL_MUT
## Elfn1 8.194523e-65 -2.3028972 0.180 0.019 2.458357e-61 CTL_MUT
## Pnlip 1.005455e-64 -4.9450310 0.101 0.003 3.016366e-61 CTL_MUT
## Mobp 1.036100e-64 2.4380699 0.242 0.233 3.108299e-61 CTL_MUT
## Gadd45g 1.112589e-64 -1.8087460 0.145 0.117 3.337768e-61 CTL_MUT
## Axdnd1 1.407438e-64 -0.6689598 0.183 0.005 4.222313e-61 CTL_MUT
## Prox1 1.624667e-64 -3.2759051 0.165 0.050 4.874001e-61 CTL_MUT
## Pid1 2.001896e-64 -0.6999875 0.273 0.220 6.005689e-61 CTL_MUT
## Sgcz 2.369092e-64 -3.9748451 0.395 0.335 7.107277e-61 CTL_MUT
## Hrct1 2.650578e-64 4.7024551 0.104 0.003 7.951734e-61 CTL_MUT
## Gm29508 3.320430e-64 -1.3024412 0.126 0.002 9.961291e-61 CTL_MUT
## Klhdc7a 6.528799e-64 -1.6886469 0.221 0.010 1.958640e-60 CTL_MUT
## Calcrl 7.082517e-64 4.3651771 0.161 0.020 2.124755e-60 CTL_MUT
## Cyp2d22 9.168029e-64 7.0109726 0.180 0.031 2.750409e-60 CTL_MUT
## St8sia4 9.255575e-64 -8.1001077 0.160 0.031 2.776672e-60 CTL_MUT
## Slc40a1 1.269763e-63 5.9394332 0.139 0.027 3.809289e-60 CTL_MUT
## Rbpms2 1.634595e-63 9.0047926 0.150 0.005 4.903785e-60 CTL_MUT
## Eogt 1.741235e-63 -1.5815131 0.178 0.051 5.223704e-60 CTL_MUT
## Cped1 2.303161e-63 -3.5869271 0.164 0.018 6.909484e-60 CTL_MUT
## Gm31946 2.352043e-63 3.7958305 0.182 0.003 7.056128e-60 CTL_MUT
## Ptpn18 2.769474e-63 -0.9169452 0.171 0.018 8.308423e-60 CTL_MUT
## Tbc1d4 6.088938e-63 -2.7739717 0.126 0.050 1.826681e-59 CTL_MUT
## 4930467D21Rik 8.111805e-63 4.6177647 0.134 0.043 2.433541e-59 CTL_MUT
## Ttc9b 9.297299e-63 -5.0535889 0.326 0.392 2.789190e-59 CTL_MUT
## Sox5os4 9.930161e-63 -0.7413783 0.190 0.018 2.979048e-59 CTL_MUT
## Efcab11 1.155634e-62 -0.3895101 0.144 0.007 3.466903e-59 CTL_MUT
## Itpkb 1.279738e-62 -2.9184375 0.176 0.026 3.839213e-59 CTL_MUT
## Tmpo 1.359758e-62 -5.6120203 0.174 0.065 4.079273e-59 CTL_MUT
## Pld4 1.685150e-62 8.4523695 0.130 0.016 5.055449e-59 CTL_MUT
## Galnt6 3.122093e-62 0.8532550 0.132 0.014 9.366278e-59 CTL_MUT
## Myo10 5.231744e-62 -4.8945267 0.180 0.091 1.569523e-58 CTL_MUT
## Cep112 7.448020e-62 9.6907132 0.233 0.147 2.234406e-58 CTL_MUT
## Gal3st1 7.918830e-62 -6.8728189 0.165 0.031 2.375649e-58 CTL_MUT
## Rdx 1.239467e-61 0.7812906 0.260 0.221 3.718401e-58 CTL_MUT
## Col23a1 1.352681e-61 -2.5098293 0.222 0.032 4.058042e-58 CTL_MUT
## Scarf2 1.374860e-61 0.7282364 0.133 0.002 4.124580e-58 CTL_MUT
## Plekhg1 1.743118e-61 2.9044963 0.185 0.124 5.229355e-58 CTL_MUT
## Prkcq 2.732722e-61 -2.2104669 0.142 0.036 8.198166e-58 CTL_MUT
## Rfx4 3.309834e-61 -2.8448796 0.171 0.059 9.929503e-58 CTL_MUT
## Ywhah 3.348311e-61 -0.7211137 0.320 0.405 1.004493e-57 CTL_MUT
## Hip1 4.252809e-61 -1.6932538 0.225 0.176 1.275843e-57 CTL_MUT
## Itgb8 4.648483e-61 -1.7643598 0.186 0.096 1.394545e-57 CTL_MUT
## Dock1 6.799756e-61 -2.4220107 0.186 0.102 2.039927e-57 CTL_MUT
## Gm21798 1.085733e-60 -2.5444479 0.170 0.035 3.257199e-57 CTL_MUT
## Itgam 1.150162e-60 2.1827815 0.137 0.017 3.450487e-57 CTL_MUT
## Tnc 1.672703e-60 -2.6607098 0.174 0.007 5.018108e-57 CTL_MUT
## Tubb2b 2.201659e-60 -1.5708103 0.203 0.138 6.604976e-57 CTL_MUT
## Sulf1 2.467385e-60 -3.7001528 0.177 0.058 7.402155e-57 CTL_MUT
## Ctnna2 2.651828e-60 -0.9296963 0.477 0.410 7.955483e-57 CTL_MUT
## Hydin 2.669295e-60 -2.1177339 0.184 0.004 8.007884e-57 CTL_MUT
## Birc2 7.719759e-60 2.8477564 0.201 0.073 2.315928e-56 CTL_MUT
## Slit2 1.135695e-59 4.1942135 0.199 0.128 3.407084e-56 CTL_MUT
## Agmat 2.057498e-59 -3.5128176 0.123 0.002 6.172495e-56 CTL_MUT
## Gm1604a 2.065092e-59 8.0800716 0.155 0.023 6.195276e-56 CTL_MUT
## Phldb2 3.126630e-59 -2.5999527 0.173 0.023 9.379891e-56 CTL_MUT
## Csmd3 3.316647e-59 -1.1930687 0.434 0.399 9.949942e-56 CTL_MUT
## Nxph2 3.947000e-59 -2.8401752 0.195 0.007 1.184100e-55 CTL_MUT
## Itga6 4.255173e-59 -6.3126112 0.165 0.050 1.276552e-55 CTL_MUT
## Ccnd1 4.335395e-59 4.0108048 0.203 0.050 1.300619e-55 CTL_MUT
## Pcsk5 6.635539e-59 -2.7642710 0.235 0.112 1.990662e-55 CTL_MUT
## Grin2c 8.939647e-59 2.7464829 0.177 0.046 2.681894e-55 CTL_MUT
## H2-K1 1.212184e-58 7.7821907 0.167 0.031 3.636552e-55 CTL_MUT
## Clec4a3 1.564732e-58 -1.1569976 0.135 0.004 4.694196e-55 CTL_MUT
## Hs3st4 1.909941e-58 -2.2472676 0.281 0.243 5.729822e-55 CTL_MUT
## Gm5083 2.022755e-58 0.8876882 0.131 0.002 6.068264e-55 CTL_MUT
## Cntnap3 2.703352e-58 -4.7322848 0.146 0.020 8.110056e-55 CTL_MUT
## Wipf1 3.127685e-58 -1.8556659 0.175 0.068 9.383055e-55 CTL_MUT
## Scrg1 3.155106e-58 2.2237230 0.207 0.130 9.465319e-55 CTL_MUT
## Lbh 3.929504e-58 -4.2606880 0.177 0.048 1.178851e-54 CTL_MUT
## Ltbp1 5.167244e-58 -9.9587457 0.195 0.039 1.550173e-54 CTL_MUT
## Sncb 5.752907e-58 0.2968967 0.235 0.321 1.725872e-54 CTL_MUT
## Gamt 5.787277e-58 -7.5764133 0.165 0.086 1.736183e-54 CTL_MUT
## Il1r1 5.939660e-58 -3.0226552 0.165 0.011 1.781898e-54 CTL_MUT
## Gltp 7.540010e-58 -8.6949938 0.187 0.065 2.262003e-54 CTL_MUT
## Aldh1a1 7.858863e-58 -1.0181269 0.174 0.068 2.357659e-54 CTL_MUT
## Ctsh 1.019579e-57 -11.1516034 0.112 0.040 3.058737e-54 CTL_MUT
## Pdzrn4 1.131407e-57 1.7568637 0.307 0.271 3.394221e-54 CTL_MUT
## Trim25 1.288594e-57 0.5820973 0.195 0.008 3.865782e-54 CTL_MUT
## Plin4 1.329645e-57 -3.8101898 0.189 0.013 3.988934e-54 CTL_MUT
## Reep5 1.346447e-57 -5.9762438 0.364 0.370 4.039341e-54 CTL_MUT
## Cenph 1.532068e-57 -8.1532717 0.161 0.006 4.596204e-54 CTL_MUT
## Dscam 1.564325e-57 2.3206340 0.427 0.384 4.692976e-54 CTL_MUT
## Grik2 1.685848e-57 2.0847377 0.427 0.392 5.057544e-54 CTL_MUT
## Lamb2 2.626466e-57 -12.7059374 0.190 0.017 7.879398e-54 CTL_MUT
## Krt12 2.847744e-57 -4.1882820 0.137 0.092 8.543232e-54 CTL_MUT
## Plet1os 3.144000e-57 -13.2708617 0.153 0.005 9.432001e-54 CTL_MUT
## Xlr 3.715635e-57 -0.5792603 0.139 0.003 1.114690e-53 CTL_MUT
## Gm28153 4.267890e-57 -9.5617381 0.142 0.014 1.280367e-53 CTL_MUT
## Fyn 4.494174e-57 4.2100872 0.279 0.258 1.348252e-53 CTL_MUT
## Ankub1 6.857512e-57 2.5500536 0.147 0.008 2.057254e-53 CTL_MUT
## Calml4 7.516231e-57 -1.0889024 0.106 0.002 2.254869e-53 CTL_MUT
## Dpysl3 9.604586e-57 -1.3619235 0.184 0.075 2.881376e-53 CTL_MUT
## Gm10785 1.109131e-56 -12.5409423 0.184 0.097 3.327393e-53 CTL_MUT
## Hdac8 1.163879e-56 1.3106158 0.302 0.252 3.491636e-53 CTL_MUT
## Emx2 1.378294e-56 -1.8719401 0.181 0.034 4.134882e-53 CTL_MUT
## Fzd1 1.763275e-56 5.7115319 0.208 0.014 5.289825e-53 CTL_MUT
## Adamts17 1.866506e-56 -2.3483869 0.185 0.098 5.599517e-53 CTL_MUT
## Sqor 2.426240e-56 -9.0823751 0.172 0.007 7.278721e-53 CTL_MUT
## Tppp3 2.717147e-56 1.6481088 0.151 0.066 8.151441e-53 CTL_MUT
## Gm17660 2.928368e-56 -4.1161359 0.132 0.006 8.785103e-53 CTL_MUT
## Pcdh17 3.229441e-56 1.2634523 0.310 0.319 9.688322e-53 CTL_MUT
## Ly6h 3.317805e-56 0.8583275 0.323 0.387 9.953414e-53 CTL_MUT
## Kcnh5 3.405378e-56 9.6302421 0.216 0.153 1.021613e-52 CTL_MUT
## Ctnna3 3.495253e-56 -1.1217562 0.385 0.361 1.048576e-52 CTL_MUT
## Slco3a1 5.094685e-56 0.6441667 0.243 0.171 1.528406e-52 CTL_MUT
## Tcf7l2 7.056089e-56 0.5854868 0.130 0.082 2.116827e-52 CTL_MUT
## Gm16316 7.107262e-56 -4.1807240 0.226 0.004 2.132179e-52 CTL_MUT
## Pik3r3 7.278629e-56 1.3100938 0.208 0.134 2.183589e-52 CTL_MUT
## Alpl 7.735294e-56 -2.8620950 0.153 0.006 2.320588e-52 CTL_MUT
## Smco4 7.897102e-56 -1.6974010 0.222 0.013 2.369131e-52 CTL_MUT
## Dok1 1.077433e-55 2.5731052 0.166 0.002 3.232298e-52 CTL_MUT
## Zbtb20 1.168638e-55 2.1090545 0.360 0.340 3.505914e-52 CTL_MUT
## Ptma 1.796291e-55 -1.2306000 0.395 0.380 5.388874e-52 CTL_MUT
## Slc35f3 1.828672e-55 -5.6409167 0.261 0.182 5.486016e-52 CTL_MUT
## Vcam1 1.893693e-55 -6.1538224 0.203 0.034 5.681079e-52 CTL_MUT
## Sorbs1 2.161655e-55 -1.4014559 0.331 0.301 6.484966e-52 CTL_MUT
## Cdh18 2.747464e-55 -6.0224815 0.307 0.260 8.242392e-52 CTL_MUT
## Phka1 3.050255e-55 -4.6870424 0.145 0.095 9.150765e-52 CTL_MUT
## Itgb5 3.275770e-55 1.0099254 0.121 0.062 9.827310e-52 CTL_MUT
## Myocd 3.438652e-55 -5.6076634 0.160 0.016 1.031595e-51 CTL_MUT
## Ndufa4 4.205813e-55 2.9369875 0.349 0.410 1.261744e-51 CTL_MUT
## Dnajb1 4.976327e-55 0.5524833 0.177 0.063 1.492898e-51 CTL_MUT
## Erbb3 5.629449e-55 -1.6190011 0.157 0.019 1.688835e-51 CTL_MUT
## Abca9 6.055385e-55 -0.7990872 0.101 0.026 1.816616e-51 CTL_MUT
## Cd300c2 6.590417e-55 6.4988345 0.134 0.023 1.977125e-51 CTL_MUT
## Emx2os 7.657902e-55 -7.1843215 0.159 0.026 2.297371e-51 CTL_MUT
## Ppia 7.974055e-55 -0.9070401 0.327 0.396 2.392217e-51 CTL_MUT
## Gng12 8.197110e-55 -1.4049929 0.270 0.199 2.459133e-51 CTL_MUT
## Adap2os 9.604074e-55 2.7818737 0.151 0.011 2.881222e-51 CTL_MUT
## Zic3 1.615528e-54 -3.7568985 0.157 0.009 4.846583e-51 CTL_MUT
## Gm31614 1.701948e-54 1.1949274 0.131 0.003 5.105844e-51 CTL_MUT
## Mdga2 1.757885e-54 -1.0274604 0.471 0.415 5.273654e-51 CTL_MUT
## Sgcd 1.950340e-54 -1.9286254 0.338 0.303 5.851020e-51 CTL_MUT
## Pth2r 2.128494e-54 -2.5454995 0.174 0.007 6.385483e-51 CTL_MUT
## Shisa9 4.652095e-54 -4.9328873 0.319 0.298 1.395629e-50 CTL_MUT
## Chchd10 5.170912e-54 0.4683699 0.361 0.426 1.551274e-50 CTL_MUT
## Gng3 5.395026e-54 -0.5766125 0.259 0.342 1.618508e-50 CTL_MUT
## B4galt1 5.687928e-54 -3.0324138 0.132 0.044 1.706378e-50 CTL_MUT
## Sv2c 5.818441e-54 -0.8278168 0.158 0.025 1.745532e-50 CTL_MUT
## Mme 6.723776e-54 -3.7134774 0.229 0.009 2.017133e-50 CTL_MUT
## Tmem132d 7.858195e-54 18.6278626 0.362 0.312 2.357459e-50 CTL_MUT
## Creb5 8.507718e-54 -6.7647093 0.162 0.058 2.552315e-50 CTL_MUT
## Atp5g1 1.144371e-53 -0.6402102 0.347 0.416 3.433112e-50 CTL_MUT
## Gm17268 1.792681e-53 -1.3919930 0.110 0.003 5.378042e-50 CTL_MUT
## Cdkn2c 2.198411e-53 -3.5450439 0.163 0.008 6.595234e-50 CTL_MUT
## A230006K03Rik 3.434591e-53 -0.5843986 0.366 0.341 1.030377e-49 CTL_MUT
## Lrrk1 4.698878e-53 -6.1719831 0.159 0.015 1.409664e-49 CTL_MUT
## Tiparp 4.863375e-53 3.7921654 0.170 0.091 1.459012e-49 CTL_MUT
## Fchsd2 5.759981e-53 0.7550925 0.210 0.151 1.727994e-49 CTL_MUT
## Gfra1 6.840115e-53 -7.4311095 0.187 0.045 2.052034e-49 CTL_MUT
## Prr5l 6.886731e-53 -11.6297831 0.151 0.064 2.066019e-49 CTL_MUT
## Piezo1 7.086377e-53 -0.6784201 0.166 0.012 2.125913e-49 CTL_MUT
## Nr4a2 9.353541e-53 -3.1549089 0.185 0.034 2.806062e-49 CTL_MUT
## Lypd6 1.210821e-52 -2.6495177 0.182 0.046 3.632463e-49 CTL_MUT
## Slc24a3 1.286856e-52 1.1154146 0.277 0.238 3.860567e-49 CTL_MUT
## Xylt1 1.460447e-52 -1.7851471 0.345 0.277 4.381341e-49 CTL_MUT
## Arrdc3 2.143674e-52 -0.9069554 0.171 0.062 6.431023e-49 CTL_MUT
## Egfr 2.166399e-52 2.4645782 0.131 0.076 6.499198e-49 CTL_MUT
## 2610035D17Rik 2.511735e-52 -9.2882984 0.212 0.114 7.535204e-49 CTL_MUT
## Apbb1ip 2.883548e-52 -3.8661160 0.120 0.030 8.650643e-49 CTL_MUT
## Idh2 3.812654e-52 -4.1496113 0.172 0.085 1.143796e-48 CTL_MUT
## Cck 4.587788e-52 2.4955315 0.276 0.351 1.376336e-48 CTL_MUT
## Kctd12 5.228084e-52 -0.8896407 0.151 0.074 1.568425e-48 CTL_MUT
## Cd81 5.768372e-52 -1.1067259 0.366 0.351 1.730512e-48 CTL_MUT
## Nkain3 5.843301e-52 -3.2675214 0.194 0.128 1.752990e-48 CTL_MUT
## Mctp1 6.477715e-52 -2.0139564 0.364 0.335 1.943314e-48 CTL_MUT
## Cspg4 8.490099e-52 -1.0422143 0.126 0.024 2.547030e-48 CTL_MUT
## Scgb3a1 9.631482e-52 -1.4575248 0.138 0.004 2.889445e-48 CTL_MUT
## Xkr6 9.878197e-52 0.7036235 0.262 0.207 2.963459e-48 CTL_MUT
## Col9a1 1.056331e-51 -2.0796185 0.199 0.004 3.168994e-48 CTL_MUT
## Gm1698 1.132308e-51 -3.6300075 0.122 0.006 3.396924e-48 CTL_MUT
## Jam2 1.284227e-51 7.3779674 0.192 0.044 3.852682e-48 CTL_MUT
## Agbl4 1.333653e-51 -2.9877038 0.407 0.366 4.000959e-48 CTL_MUT
## Etv6 1.354499e-51 0.8641265 0.269 0.200 4.063496e-48 CTL_MUT
## Msi2 1.465703e-51 -1.5500900 0.357 0.337 4.397108e-48 CTL_MUT
## Tst 1.576726e-51 -6.5091371 0.222 0.059 4.730177e-48 CTL_MUT
## Clic1 1.578033e-51 0.4519139 0.146 0.052 4.734100e-48 CTL_MUT
## Mob3b 1.611544e-51 -6.6579183 0.156 0.029 4.834633e-48 CTL_MUT
## Stox2 2.791128e-51 0.6203705 0.378 0.359 8.373383e-48 CTL_MUT
## Adarb2 3.172673e-51 0.7724594 0.184 0.152 9.518018e-48 CTL_MUT
## BB557941 3.722558e-51 -6.4082843 0.164 0.004 1.116767e-47 CTL_MUT
## Dynll1 3.907006e-51 -0.5176270 0.305 0.375 1.172102e-47 CTL_MUT
## Clec4a2 4.514210e-51 -9.7458282 0.135 0.005 1.354263e-47 CTL_MUT
## Mbp 5.519407e-51 -0.5086415 0.322 0.288 1.655822e-47 CTL_MUT
## Itpripl1 5.760791e-51 -1.1149339 0.115 0.002 1.728237e-47 CTL_MUT
## Pltp 6.550059e-51 -2.1584431 0.103 0.072 1.965018e-47 CTL_MUT
## Stk32a 6.824809e-51 -1.6852826 0.115 0.020 2.047443e-47 CTL_MUT
## Dgkb 8.886864e-51 -7.3426873 0.390 0.377 2.666059e-47 CTL_MUT
## Sox8 1.273175e-50 -4.5869049 0.192 0.050 3.819525e-47 CTL_MUT
## A330049N07Rik 1.279218e-50 0.9545815 0.151 0.008 3.837654e-47 CTL_MUT
## Ly6e 1.505106e-50 5.2635540 0.195 0.227 4.515317e-47 CTL_MUT
## Gsn 1.947876e-50 -3.5602944 0.175 0.097 5.843628e-47 CTL_MUT
## Tnr 2.334573e-50 -3.7372390 0.387 0.362 7.003720e-47 CTL_MUT
## Gpsm3 2.513992e-50 -3.0062144 0.139 0.005 7.541977e-47 CTL_MUT
## Rorb 2.929065e-50 -0.4894441 0.278 0.289 8.787196e-47 CTL_MUT
## Pls1 3.108932e-50 -2.4866675 0.199 0.051 9.326797e-47 CTL_MUT
## Trps1 3.133159e-50 2.2341566 0.304 0.256 9.399476e-47 CTL_MUT
## Cald1 3.194714e-50 -4.5484716 0.146 0.072 9.584141e-47 CTL_MUT
## Ppp1r16b 3.299530e-50 -3.0246048 0.246 0.164 9.898589e-47 CTL_MUT
## Usp54 4.044355e-50 3.0592998 0.228 0.133 1.213307e-46 CTL_MUT
## Dlc1 5.057016e-50 -0.7004352 0.304 0.253 1.517105e-46 CTL_MUT
## Gja4 6.374617e-50 -2.0551814 0.102 0.004 1.912385e-46 CTL_MUT
## Cdc14a 6.612480e-50 -0.4464247 0.171 0.022 1.983744e-46 CTL_MUT
## Dsn1 6.646921e-50 -2.5057238 0.190 0.005 1.994076e-46 CTL_MUT
## Ang 1.039792e-49 1.3403464 0.182 0.010 3.119377e-46 CTL_MUT
## St18 1.119385e-49 -0.8944125 0.192 0.115 3.358155e-46 CTL_MUT
## Creb3l2 1.419109e-49 -2.0940639 0.155 0.044 4.257326e-46 CTL_MUT
## Fbxl7 1.489061e-49 -2.4327679 0.143 0.051 4.467184e-46 CTL_MUT
## Mex3a 1.559241e-49 -2.8839151 0.157 0.010 4.677722e-46 CTL_MUT
## B230319C09Rik 1.730769e-49 -1.0798144 0.107 0.002 5.192307e-46 CTL_MUT
## C030005K06Rik 1.783100e-49 3.3414126 0.180 0.013 5.349301e-46 CTL_MUT
## Tmc1 1.826006e-49 -0.8186875 0.127 0.002 5.478017e-46 CTL_MUT
## Khdrbs2 2.270130e-49 5.7950943 0.368 0.340 6.810390e-46 CTL_MUT
## Scpep1os 2.306187e-49 -6.5141697 0.226 0.007 6.918561e-46 CTL_MUT
## Syne3 2.354294e-49 -1.2457005 0.230 0.009 7.062881e-46 CTL_MUT
## Cort 2.975667e-49 -1.1801969 0.130 0.039 8.927002e-46 CTL_MUT
## Maob 3.775351e-49 -3.7692581 0.160 0.052 1.132605e-45 CTL_MUT
## Prr5 4.224236e-49 -2.6669209 0.197 0.019 1.267271e-45 CTL_MUT
## Gm47872 4.543684e-49 -2.1845810 0.112 0.001 1.363105e-45 CTL_MUT
## Morrbid 5.000484e-49 3.7853940 0.174 0.009 1.500145e-45 CTL_MUT
## Rexo5 5.796089e-49 -3.1186510 0.154 0.004 1.738827e-45 CTL_MUT
## Chsy3 6.630681e-49 -0.9544812 0.379 0.339 1.989204e-45 CTL_MUT
## Tnfaip8l3 7.889338e-49 -8.9472238 0.143 0.013 2.366801e-45 CTL_MUT
## Sgms2 8.360834e-49 2.8535395 0.161 0.009 2.508250e-45 CTL_MUT
## Meis2 8.377235e-49 2.9197748 0.369 0.376 2.513170e-45 CTL_MUT
## Slc22a8 8.781767e-49 -4.2631189 0.123 0.017 2.634530e-45 CTL_MUT
## Epb41l2 9.109389e-49 -7.2176108 0.209 0.184 2.732817e-45 CTL_MUT
## Gm34455 1.024802e-48 -5.1360642 0.205 0.004 3.074407e-45 CTL_MUT
## Pdgfra 1.089940e-48 -5.2252159 0.100 0.045 3.269819e-45 CTL_MUT
## P2ry12 1.217958e-48 -5.7646330 0.126 0.079 3.653875e-45 CTL_MUT
## Igfbp7 1.612108e-48 -3.0335459 0.119 0.093 4.836325e-45 CTL_MUT
## Ccdc3 1.825757e-48 3.3639540 0.192 0.030 5.477272e-45 CTL_MUT
## Spock2 2.637159e-48 1.7313207 0.311 0.388 7.911478e-45 CTL_MUT
## Acvrl1 3.633942e-48 5.6209005 0.131 0.019 1.090183e-44 CTL_MUT
## Slc24a2 5.242899e-48 -0.8945639 0.431 0.398 1.572870e-44 CTL_MUT
## Cmtm8 5.628709e-48 -1.9569878 0.143 0.015 1.688613e-44 CTL_MUT
## 2610307P16Rik 5.654257e-48 -5.9601931 0.110 0.031 1.696277e-44 CTL_MUT
## Sys1 5.693539e-48 3.3451228 0.222 0.191 1.708062e-44 CTL_MUT
## Gm12153 5.831346e-48 -0.5291220 0.135 0.005 1.749404e-44 CTL_MUT
## AW551984 6.492170e-48 -1.2572501 0.130 0.003 1.947651e-44 CTL_MUT
## Nes 7.205302e-48 -8.1099680 0.158 0.010 2.161591e-44 CTL_MUT
## Fli1 8.577889e-48 -3.6326031 0.112 0.046 2.573367e-44 CTL_MUT
## Bank1 9.426535e-48 -0.7918727 0.146 0.010 2.827961e-44 CTL_MUT
## Fam189a1 1.249126e-47 -0.7098928 0.332 0.282 3.747379e-44 CTL_MUT
## Fras1 1.337714e-47 2.0934675 0.209 0.124 4.013143e-44 CTL_MUT
## Ets1 1.438089e-47 8.3571070 0.147 0.021 4.314267e-44 CTL_MUT
## St6galnac5 1.734492e-47 -3.4971122 0.277 0.220 5.203477e-44 CTL_MUT
## Gm16853 1.739875e-47 6.4329982 0.212 0.004 5.219626e-44 CTL_MUT
## Qdpr 1.875641e-47 -4.0147348 0.248 0.185 5.626923e-44 CTL_MUT
## Ndrg1 2.108972e-47 1.1125680 0.187 0.090 6.326916e-44 CTL_MUT
## Slc38a3 2.176420e-47 -8.1305353 0.190 0.022 6.529260e-44 CTL_MUT
## Gm30524 2.927743e-47 -1.4802187 0.162 0.003 8.783228e-44 CTL_MUT
## Adora2b 4.287844e-47 -1.5124527 0.182 0.009 1.286353e-43 CTL_MUT
## Gm48091 4.569374e-47 0.2747682 0.195 0.087 1.370812e-43 CTL_MUT
## Abi3bp 5.873215e-47 -6.7287597 0.168 0.047 1.761965e-43 CTL_MUT
## Ccbe1 6.658148e-47 5.1847644 0.126 0.089 1.997444e-43 CTL_MUT
## Htra1 1.025800e-46 3.7197015 0.226 0.205 3.077401e-43 CTL_MUT
## Dach1 1.458001e-46 0.3868688 0.146 0.044 4.374003e-43 CTL_MUT
## Bmp6 2.065453e-46 -1.9947984 0.107 0.006 6.196360e-43 CTL_MUT
## Dlg2 2.285930e-46 -0.3509190 0.502 0.432 6.857791e-43 CTL_MUT
## Cebpb 2.638816e-46 2.8910027 0.129 0.058 7.916448e-43 CTL_MUT
## Slc7a1 3.139297e-46 4.3129053 0.143 0.083 9.417891e-43 CTL_MUT
## Dcx 4.010297e-46 -2.4247088 0.225 0.159 1.203089e-42 CTL_MUT
## Ccdc114 4.397890e-46 -2.4254555 0.133 0.004 1.319367e-42 CTL_MUT
## Galnt17 6.674463e-46 2.1298304 0.290 0.266 2.002339e-42 CTL_MUT
## Adrb2 6.961038e-46 -3.7890018 0.122 0.016 2.088311e-42 CTL_MUT
## Olig1 9.690633e-46 -3.2317984 0.205 0.123 2.907190e-42 CTL_MUT
## Vit 1.417727e-45 -1.9015818 0.197 0.006 4.253181e-42 CTL_MUT
## Nhsl1 1.547106e-45 -6.7049544 0.151 0.069 4.641318e-42 CTL_MUT
## Cdh7 1.745739e-45 -4.2206622 0.163 0.087 5.237217e-42 CTL_MUT
## Ctxn1 2.177766e-45 0.6740381 0.284 0.375 6.533297e-42 CTL_MUT
## Fam214a 2.186805e-45 -7.4222668 0.239 0.176 6.560416e-42 CTL_MUT
## Atp6v1g2 2.896742e-45 3.2657094 0.262 0.336 8.690226e-42 CTL_MUT
## Pde7b 2.902958e-45 0.7229018 0.256 0.218 8.708875e-42 CTL_MUT
## Nek7 2.963844e-45 2.2190880 0.180 0.093 8.891532e-42 CTL_MUT
## Slc2a13 3.714123e-45 -0.9084026 0.310 0.288 1.114237e-41 CTL_MUT
## Serpinb6b 6.681975e-45 -2.2158908 0.114 0.005 2.004592e-41 CTL_MUT
## Mapk4 6.984642e-45 -7.9261295 0.244 0.226 2.095393e-41 CTL_MUT
## 4930550C14Rik 8.132938e-45 -1.1474034 0.160 0.003 2.439881e-41 CTL_MUT
## Bcas1os2 1.178237e-44 -4.2299926 0.162 0.009 3.534712e-41 CTL_MUT
## Gm14204 1.475244e-44 -5.8622427 0.120 0.019 4.425733e-41 CTL_MUT
## Gm26871 1.761248e-44 -2.6243906 0.402 0.366 5.283744e-41 CTL_MUT
## E130215H24Rik 2.233296e-44 -4.1201243 0.122 0.003 6.699887e-41 CTL_MUT
## Fmo2 2.415406e-44 -1.2686271 0.174 0.004 7.246217e-41 CTL_MUT
## Cav1 2.989536e-44 8.0880662 0.147 0.015 8.968607e-41 CTL_MUT
## Gpr158 2.996865e-44 -1.5210445 0.387 0.359 8.990596e-41 CTL_MUT
## Hist1h1c 3.246316e-44 -9.6420225 0.186 0.070 9.738949e-41 CTL_MUT
## Galnt13 3.461888e-44 1.0444887 0.328 0.283 1.038566e-40 CTL_MUT
## Plscr4 3.561620e-44 3.3920933 0.164 0.014 1.068486e-40 CTL_MUT
## 6330403K07Rik 3.652407e-44 -3.9613565 0.221 0.290 1.095722e-40 CTL_MUT
## Rspo2 3.669852e-44 4.3996981 0.163 0.073 1.100956e-40 CTL_MUT
## Ptprk 4.732217e-44 -1.9940218 0.384 0.368 1.419665e-40 CTL_MUT
## Tesk2 4.810569e-44 -7.8095910 0.214 0.052 1.443171e-40 CTL_MUT
## Gm9750 6.122809e-44 6.1038562 0.181 0.011 1.836843e-40 CTL_MUT
## Dlx6os1 6.472206e-44 -7.5744399 0.115 0.060 1.941662e-40 CTL_MUT
## Cdh10 1.401516e-43 -0.8750120 0.397 0.379 4.204548e-40 CTL_MUT
## Dtna 1.431122e-43 -0.6200404 0.396 0.386 4.293367e-40 CTL_MUT
## Gstm1 1.443388e-43 2.0946353 0.230 0.227 4.330165e-40 CTL_MUT
## Kcnn2 1.486787e-43 -7.1087665 0.307 0.266 4.460362e-40 CTL_MUT
## Gm16599 1.578034e-43 -2.2581622 0.180 0.082 4.734103e-40 CTL_MUT
## Shisa6 1.840356e-43 7.1937706 0.165 0.070 5.521068e-40 CTL_MUT
## Rassf2 2.248215e-43 -0.2574955 0.185 0.046 6.744645e-40 CTL_MUT
## Phldb1 2.338286e-43 -7.5665884 0.169 0.068 7.014858e-40 CTL_MUT
## Hmgn5 2.746676e-43 -14.7797453 0.183 0.031 8.240029e-40 CTL_MUT
## Tead1 3.039773e-43 2.0072297 0.181 0.120 9.119319e-40 CTL_MUT
## Pag1 3.158837e-43 0.8960624 0.176 0.113 9.476510e-40 CTL_MUT
## Gapdh 3.834798e-43 0.4437964 0.333 0.384 1.150439e-39 CTL_MUT
## Plcg2 3.854150e-43 3.7258157 0.130 0.010 1.156245e-39 CTL_MUT
## Igfbp5 6.741324e-43 -2.4119205 0.164 0.112 2.022397e-39 CTL_MUT
## Klf12 8.405279e-43 -4.8386293 0.365 0.305 2.521584e-39 CTL_MUT
## Sox7 9.819223e-43 -1.6066536 0.113 0.003 2.945767e-39 CTL_MUT
## Gm48877 9.988304e-43 -3.2466297 0.104 0.002 2.996491e-39 CTL_MUT
## Rab37 1.021713e-42 -3.6968533 0.114 0.002 3.065139e-39 CTL_MUT
## Tlcd1 1.067361e-42 -10.0223941 0.202 0.027 3.202083e-39 CTL_MUT
## Pde10a 1.188917e-42 -2.2225738 0.386 0.356 3.566751e-39 CTL_MUT
## Grip1 1.736297e-42 -1.2501474 0.293 0.279 5.208890e-39 CTL_MUT
## Wdr17 1.912939e-42 -0.6183531 0.356 0.370 5.738817e-39 CTL_MUT
## Dbndd2 1.944573e-42 -5.4115513 0.259 0.189 5.833720e-39 CTL_MUT
## A730011C13Rik 2.034597e-42 -0.8371072 0.156 0.002 6.103792e-39 CTL_MUT
## Sema3c 2.670988e-42 6.8414342 0.115 0.067 8.012964e-39 CTL_MUT
## Zic5 4.204895e-42 -0.3629730 0.193 0.011 1.261469e-38 CTL_MUT
## Ndufa4l2 6.623564e-42 6.0721288 0.125 0.012 1.987069e-38 CTL_MUT
## Mro 7.649025e-42 1.7892390 0.162 0.047 2.294708e-38 CTL_MUT
## Dnah6 7.938719e-42 -1.4039068 0.219 0.004 2.381616e-38 CTL_MUT
## Fa2h 8.408523e-42 -9.9724199 0.129 0.052 2.522557e-38 CTL_MUT
## Sash1 8.654857e-42 14.0758964 0.217 0.137 2.596457e-38 CTL_MUT
## Srgap2 1.617815e-41 -0.8796063 0.376 0.377 4.853445e-38 CTL_MUT
## Gm37885 2.213236e-41 2.9981813 0.136 0.004 6.639709e-38 CTL_MUT
## Igfbp6 2.954129e-41 2.9279587 0.115 0.126 8.862387e-38 CTL_MUT
## Dock4 3.559636e-41 1.7102942 0.412 0.406 1.067891e-37 CTL_MUT
## Nfkbia 3.935521e-41 2.4674592 0.173 0.105 1.180656e-37 CTL_MUT
## Gm26737 4.529915e-41 -0.5147737 0.153 0.002 1.358974e-37 CTL_MUT
## Gm28981 5.597953e-41 -0.9061219 0.145 0.002 1.679386e-37 CTL_MUT
## Npy2r 5.888643e-41 -1.7316921 0.113 0.005 1.766593e-37 CTL_MUT
## Nap1l5 8.252272e-41 1.8058538 0.274 0.302 2.475682e-37 CTL_MUT
## Ugt8a 8.286556e-41 -8.0344021 0.201 0.122 2.485967e-37 CTL_MUT
## Gm10561 8.665545e-41 -4.8374649 0.201 0.009 2.599664e-37 CTL_MUT
## Angpt1 1.282507e-40 11.4781796 0.179 0.047 3.847520e-37 CTL_MUT
## Cmtm5 1.352994e-40 -0.5381050 0.212 0.126 4.058983e-37 CTL_MUT
## Fdps 1.434482e-40 8.4625107 0.184 0.113 4.303447e-37 CTL_MUT
## Gm44151 1.542242e-40 2.8612468 0.198 0.096 4.626725e-37 CTL_MUT
## Tcf7l1 1.638360e-40 -7.1377001 0.169 0.023 4.915079e-37 CTL_MUT
## Sema3e 2.319802e-40 -1.9416280 0.211 0.100 6.959407e-37 CTL_MUT
## Grik3 2.420267e-40 -1.4767974 0.232 0.125 7.260801e-37 CTL_MUT
## Egln3 3.275330e-40 0.6583614 0.179 0.007 9.825989e-37 CTL_MUT
## Gm49164 3.287091e-40 8.9174054 0.158 0.033 9.861272e-37 CTL_MUT
## Trf 3.437975e-40 -0.8371693 0.215 0.149 1.031393e-36 CTL_MUT
## Sparc 3.606823e-40 -2.6761531 0.221 0.212 1.082047e-36 CTL_MUT
## R3hdm1 3.743782e-40 -0.7581492 0.435 0.409 1.123135e-36 CTL_MUT
## Kcnt2 3.968204e-40 -3.2512714 0.357 0.331 1.190461e-36 CTL_MUT
## Msn 6.215728e-40 -0.5947114 0.150 0.041 1.864718e-36 CTL_MUT
## Adcy8 6.227601e-40 -1.2889739 0.197 0.111 1.868280e-36 CTL_MUT
## Cd59a 6.297602e-40 -0.9007929 0.113 0.037 1.889281e-36 CTL_MUT
## Nnat 8.112292e-40 -7.8715861 0.200 0.142 2.433688e-36 CTL_MUT
## Tyms 8.307791e-40 0.7490175 0.188 0.009 2.492337e-36 CTL_MUT
## Ccser1 1.440877e-39 -3.4316447 0.440 0.400 4.322630e-36 CTL_MUT
## Tenm1 1.605435e-39 -2.0603817 0.356 0.332 4.816305e-36 CTL_MUT
## Lrrc14b 1.621277e-39 1.8292342 0.206 0.003 4.863830e-36 CTL_MUT
## Vcan 1.949967e-39 3.2180964 0.121 0.072 5.849902e-36 CTL_MUT
## Tns1 1.958928e-39 -5.6653403 0.157 0.050 5.876784e-36 CTL_MUT
## 5730522E02Rik 2.173462e-39 -7.3750079 0.362 0.330 6.520386e-36 CTL_MUT
## Lair1 2.530242e-39 -0.8011718 0.158 0.039 7.590726e-36 CTL_MUT
## Dchs2 2.633651e-39 -3.0655190 0.136 0.009 7.900952e-36 CTL_MUT
## Lhfp 3.349076e-39 3.8989622 0.217 0.181 1.004723e-35 CTL_MUT
## Olfr889 3.352160e-39 -2.6418633 0.184 0.004 1.005648e-35 CTL_MUT
## Psmb9 3.370437e-39 0.6997271 0.121 0.003 1.011131e-35 CTL_MUT
## Aff3 5.001147e-39 -0.8538755 0.355 0.314 1.500344e-35 CTL_MUT
## Cntn3 5.017943e-39 -1.2678893 0.367 0.344 1.505383e-35 CTL_MUT
## A830008E24Rik 6.276742e-39 -1.5747705 0.149 0.016 1.883023e-35 CTL_MUT
## Hepacam 6.867544e-39 -1.7860004 0.215 0.153 2.060263e-35 CTL_MUT
## Cpox 8.310685e-39 2.7672619 0.174 0.091 2.493206e-35 CTL_MUT
## Lmo4 8.929334e-39 0.4643069 0.317 0.382 2.678800e-35 CTL_MUT
## Mgat4c 9.376587e-39 -9.3467448 0.327 0.314 2.812976e-35 CTL_MUT
## Npas1 9.448269e-39 -2.0769570 0.130 0.015 2.834481e-35 CTL_MUT
## Stmn2 9.916525e-39 -1.0373852 0.342 0.410 2.974957e-35 CTL_MUT
## S100a13 1.127199e-38 -3.2870920 0.213 0.125 3.381597e-35 CTL_MUT
## Eya4 1.302651e-38 -3.4890454 0.153 0.022 3.907953e-35 CTL_MUT
## Ncf1 1.348859e-38 -8.9280748 0.114 0.018 4.046577e-35 CTL_MUT
## Ednrb 2.385665e-38 -2.9517672 0.180 0.054 7.156994e-35 CTL_MUT
## Me3 2.480950e-38 -1.7672281 0.321 0.257 7.442849e-35 CTL_MUT
## H2-D1 2.595363e-38 12.1954090 0.184 0.035 7.786089e-35 CTL_MUT
## Prss56 2.906419e-38 -0.2596680 0.152 0.000 8.719258e-35 CTL_MUT
## A830018L16Rik 3.441631e-38 -1.7015184 0.357 0.332 1.032489e-34 CTL_MUT
## Gm32151 3.820033e-38 -6.1940571 0.145 0.002 1.146010e-34 CTL_MUT
## Cxcl14 4.660720e-38 0.4124878 0.176 0.157 1.398216e-34 CTL_MUT
## Igsf11 5.378454e-38 -9.2325496 0.172 0.096 1.613536e-34 CTL_MUT
## Id2 6.573672e-38 2.0298747 0.220 0.196 1.972102e-34 CTL_MUT
## Syk 7.195746e-38 -9.3831186 0.136 0.009 2.158724e-34 CTL_MUT
## Atf3 7.794292e-38 -2.6499547 0.120 0.039 2.338287e-34 CTL_MUT
## Gm36975 8.407079e-38 2.1966381 0.229 0.156 2.522124e-34 CTL_MUT
## Nkx2-2 8.855924e-38 -4.8182942 0.178 0.011 2.656777e-34 CTL_MUT
## Gli1 9.131743e-38 -1.0844604 0.110 0.013 2.739523e-34 CTL_MUT
## Hspa1b 1.044890e-37 -6.6910516 0.214 0.013 3.134671e-34 CTL_MUT
## Dpyd 1.445609e-37 2.8448375 0.194 0.117 4.336826e-34 CTL_MUT
## Fez1 1.517374e-37 0.5288242 0.330 0.350 4.552122e-34 CTL_MUT
## AW112010 1.645547e-37 1.3160254 0.143 0.008 4.936640e-34 CTL_MUT
## Prdm16 1.710391e-37 -11.3788649 0.146 0.058 5.131174e-34 CTL_MUT
## Tmem88b 1.970163e-37 -5.4144467 0.159 0.058 5.910489e-34 CTL_MUT
## Crhbp 2.036728e-37 1.6530362 0.184 0.016 6.110183e-34 CTL_MUT
## Tmem100 2.273504e-37 -0.5986527 0.155 0.046 6.820512e-34 CTL_MUT
## Gm20618 2.909071e-37 -2.9280915 0.184 0.003 8.727214e-34 CTL_MUT
## Rab11fip1 3.030707e-37 -1.7439396 0.128 0.006 9.092121e-34 CTL_MUT
## Atp10a 3.396398e-37 -3.5875624 0.110 0.062 1.018919e-33 CTL_MUT
## Grm8 3.597816e-37 9.8135707 0.344 0.297 1.079345e-33 CTL_MUT
## Ywhaq 3.852020e-37 -1.4306388 0.356 0.365 1.155606e-33 CTL_MUT
## Dpf3 7.482887e-37 -2.6192718 0.172 0.033 2.244866e-33 CTL_MUT
## Col1a1 8.962777e-37 -0.8557292 0.121 0.005 2.688833e-33 CTL_MUT
## Tgm2 9.293929e-37 6.4924088 0.169 0.010 2.788179e-33 CTL_MUT
## Cacna1c 9.425848e-37 -0.3501703 0.411 0.384 2.827754e-33 CTL_MUT
## Ranbp3l 9.841341e-37 -8.2842757 0.141 0.030 2.952402e-33 CTL_MUT
## Cebpd 9.883114e-37 1.2804115 0.167 0.036 2.964934e-33 CTL_MUT
## Mapkapk2 1.074598e-36 7.4793603 0.176 0.053 3.223793e-33 CTL_MUT
## Cobll1 1.095751e-36 4.3099837 0.163 0.045 3.287254e-33 CTL_MUT
## Adcy10 1.388714e-36 5.0615315 0.165 0.036 4.166142e-33 CTL_MUT
## Gm44593 1.388861e-36 -1.1585448 0.166 0.018 4.166584e-33 CTL_MUT
## Cnksr3 1.455301e-36 0.5177185 0.125 0.032 4.365904e-33 CTL_MUT
## Smoc1 1.619783e-36 -5.9350923 0.195 0.022 4.859348e-33 CTL_MUT
## Tmem37 1.919671e-36 -1.2909828 0.140 0.009 5.759014e-33 CTL_MUT
## Pim1 2.212866e-36 0.4536018 0.196 0.008 6.638598e-33 CTL_MUT
## Itga1 2.952432e-36 -1.2499452 0.106 0.044 8.857296e-33 CTL_MUT
## Dgki 3.996151e-36 -0.5832802 0.438 0.398 1.198845e-32 CTL_MUT
## Lgals3bp 4.012697e-36 4.5894071 0.200 0.013 1.203809e-32 CTL_MUT
## Myof 4.657049e-36 3.8863168 0.174 0.005 1.397115e-32 CTL_MUT
## Efhd1 5.299674e-36 -2.0732670 0.165 0.035 1.589902e-32 CTL_MUT
## Slc32a1 5.660129e-36 2.1208781 0.124 0.050 1.698039e-32 CTL_MUT
## Slc35f4 5.960953e-36 -1.0706196 0.317 0.235 1.788286e-32 CTL_MUT
## Tfcp2l1 6.141886e-36 8.9827960 0.173 0.016 1.842566e-32 CTL_MUT
## Ttyh2 8.013513e-36 -9.8534043 0.167 0.027 2.404054e-32 CTL_MUT
## Cox5a 8.255817e-36 -0.9777685 0.367 0.416 2.476745e-32 CTL_MUT
## Dqx1 8.346126e-36 -1.8423378 0.164 0.003 2.503838e-32 CTL_MUT
## Cxcl12 9.778357e-36 -3.1411594 0.154 0.107 2.933507e-32 CTL_MUT
## Sec11c 1.091699e-35 6.1349854 0.250 0.251 3.275097e-32 CTL_MUT
## Slco2b1 1.697732e-35 -4.9575426 0.113 0.030 5.093196e-32 CTL_MUT
## Cd53 2.276474e-35 -5.4662181 0.141 0.019 6.829423e-32 CTL_MUT
## Stmn4 2.652964e-35 0.7674018 0.306 0.344 7.958893e-32 CTL_MUT
## Tmem47 2.772115e-35 -1.7683872 0.181 0.103 8.316344e-32 CTL_MUT
## Tll1 3.820629e-35 -4.2635421 0.173 0.013 1.146189e-31 CTL_MUT
## Tle4 5.174550e-35 2.9265079 0.242 0.219 1.552365e-31 CTL_MUT
## Palld 5.331502e-35 11.3122660 0.176 0.019 1.599451e-31 CTL_MUT
## Ppfibp1 7.987435e-35 -7.7399661 0.163 0.085 2.396231e-31 CTL_MUT
## Trpc5 1.002542e-34 7.0461176 0.189 0.129 3.007626e-31 CTL_MUT
## Mmp16 1.100382e-34 -0.7302720 0.396 0.376 3.301147e-31 CTL_MUT
## Nme7 1.461393e-34 -4.2406884 0.318 0.348 4.384179e-31 CTL_MUT
## Cd84 1.551312e-34 -1.7124123 0.103 0.012 4.653935e-31 CTL_MUT
## Adamts1 1.589460e-34 -1.7277303 0.183 0.011 4.768380e-31 CTL_MUT
## Smc4 1.641322e-34 -4.0275604 0.167 0.029 4.923965e-31 CTL_MUT
## Atrnl1 1.676638e-34 -0.9453591 0.382 0.359 5.029915e-31 CTL_MUT
## Sp8 2.146485e-34 -2.9043354 0.139 0.008 6.439456e-31 CTL_MUT
## A4galt 2.431054e-34 6.6155996 0.102 0.003 7.293162e-31 CTL_MUT
## Plp1 2.898738e-34 1.1734801 0.198 0.132 8.696215e-31 CTL_MUT
## Gm28875 3.424560e-34 -3.7501906 0.154 0.002 1.027368e-30 CTL_MUT
## Srarp 4.096968e-34 -3.8861270 0.107 0.017 1.229090e-30 CTL_MUT
## Slc6a1 4.763103e-34 -2.2332924 0.228 0.175 1.428931e-30 CTL_MUT
## Phkg1 4.793667e-34 0.6649510 0.140 0.040 1.438100e-30 CTL_MUT
## Idh1 4.956143e-34 10.3408255 0.168 0.066 1.486843e-30 CTL_MUT
## Kank3 5.043610e-34 6.3911527 0.130 0.032 1.513083e-30 CTL_MUT
## Adamts4 6.516905e-34 -2.9377657 0.142 0.025 1.955072e-30 CTL_MUT
## Bmpr1b 7.096238e-34 -2.1312157 0.168 0.096 2.128871e-30 CTL_MUT
## Slc7a2 7.306275e-34 -2.0116142 0.163 0.036 2.191882e-30 CTL_MUT
## Gm16499 9.744693e-34 -1.0414404 0.156 0.003 2.923408e-30 CTL_MUT
## Ptprd 1.099738e-33 -0.5038570 0.481 0.421 3.299213e-30 CTL_MUT
## Il18 1.562508e-33 5.4660283 0.173 0.082 4.687523e-30 CTL_MUT
## Tafa2 1.673673e-33 -3.0459696 0.289 0.253 5.021018e-30 CTL_MUT
## Plxdc2 2.278179e-33 0.6852771 0.290 0.272 6.834537e-30 CTL_MUT
## Hcls1 2.602954e-33 -3.0498150 0.112 0.005 7.808862e-30 CTL_MUT
## Heph 4.861200e-33 -0.9142328 0.172 0.014 1.458360e-29 CTL_MUT
## Fat3 5.442732e-33 -0.7758564 0.358 0.341 1.632820e-29 CTL_MUT
## Serpini1 5.758268e-33 -4.4060335 0.286 0.262 1.727480e-29 CTL_MUT
## Asap3 5.930394e-33 -0.4128197 0.205 0.009 1.779118e-29 CTL_MUT
## Olfml1 5.973918e-33 -10.0208357 0.173 0.018 1.792175e-29 CTL_MUT
## Zfp217 7.290927e-33 -11.7454989 0.160 0.005 2.187278e-29 CTL_MUT
## Gm26887 1.158455e-32 -5.2560980 0.115 0.001 3.475366e-29 CTL_MUT
## Mamdc2 1.203696e-32 -0.6876238 0.139 0.012 3.611087e-29 CTL_MUT
## Peg10 1.432006e-32 -5.4055782 0.201 0.005 4.296017e-29 CTL_MUT
## Adssl1 1.631438e-32 -9.8598751 0.147 0.033 4.894315e-29 CTL_MUT
## Tspan15 1.948503e-32 -6.8863542 0.161 0.034 5.845508e-29 CTL_MUT
## A2m 2.044747e-32 1.4348614 0.130 0.004 6.134240e-29 CTL_MUT
## Mir99ahg 2.156663e-32 -19.3655459 0.416 0.415 6.469988e-29 CTL_MUT
## Ctss 2.316775e-32 3.3327237 0.102 0.092 6.950326e-29 CTL_MUT
## Nat8 2.849766e-32 0.5983088 0.176 0.004 8.549299e-29 CTL_MUT
## Neto1 3.096773e-32 2.7844337 0.324 0.289 9.290318e-29 CTL_MUT
## Cdh9 3.302519e-32 5.6994317 0.178 0.097 9.907558e-29 CTL_MUT
## Plcd4 3.328542e-32 -6.0607977 0.172 0.037 9.985627e-29 CTL_MUT
## Arl15 3.702565e-32 -3.6323857 0.361 0.348 1.110769e-28 CTL_MUT
## Sugct 4.771919e-32 -1.4782209 0.160 0.032 1.431576e-28 CTL_MUT
## Myh15 6.218610e-32 -11.5398745 0.202 0.004 1.865583e-28 CTL_MUT
## Tmem176b 6.783005e-32 -3.2955629 0.156 0.077 2.034902e-28 CTL_MUT
## Ankrd55 7.226422e-32 0.3039897 0.112 0.014 2.167927e-28 CTL_MUT
## Gjb6 8.184206e-32 -1.0160358 0.156 0.095 2.455262e-28 CTL_MUT
## Cadps2 8.902940e-32 -4.7883341 0.265 0.203 2.670882e-28 CTL_MUT
## Fbxo2 9.254379e-32 2.2284296 0.158 0.117 2.776314e-28 CTL_MUT
## Frmd4a 9.598139e-32 1.8561232 0.402 0.361 2.879442e-28 CTL_MUT
## Cenpl 1.007664e-31 -7.3516254 0.115 0.004 3.022993e-28 CTL_MUT
## Cyp4f15 1.033655e-31 -4.8365495 0.149 0.029 3.100965e-28 CTL_MUT
## Foxp2 1.064585e-31 2.1382286 0.195 0.128 3.193754e-28 CTL_MUT
## Ptprz1 1.068530e-31 -3.5208061 0.328 0.327 3.205591e-28 CTL_MUT
## Eps8l2 1.201595e-31 2.6100859 0.149 0.003 3.604785e-28 CTL_MUT
## Lpcat2 1.219201e-31 6.1969812 0.153 0.047 3.657602e-28 CTL_MUT
## Trpc4 1.376703e-31 2.8834567 0.168 0.096 4.130108e-28 CTL_MUT
## Podxl 1.585776e-31 -2.8476161 0.157 0.023 4.757327e-28 CTL_MUT
## Gjb1 2.016067e-31 -5.4415720 0.140 0.016 6.048200e-28 CTL_MUT
## Nupr1 2.226678e-31 -2.0287182 0.209 0.031 6.680035e-28 CTL_MUT
## Cdh6 2.481088e-31 -0.8813884 0.206 0.118 7.443265e-28 CTL_MUT
## Wfdc1 2.742847e-31 1.6860301 0.113 0.021 8.228542e-28 CTL_MUT
## Vwa1 2.779523e-31 11.3617650 0.158 0.024 8.338570e-28 CTL_MUT
## Cfap77 2.993244e-31 -1.4094704 0.102 0.002 8.979731e-28 CTL_MUT
## Lgmn 3.029092e-31 12.3369883 0.178 0.130 9.087277e-28 CTL_MUT
## Sfrp1 3.149269e-31 -2.8325672 0.192 0.014 9.447806e-28 CTL_MUT
## Dock11 4.231862e-31 -0.5479195 0.144 0.047 1.269559e-27 CTL_MUT
## Igf1 5.015376e-31 -0.9654585 0.104 0.032 1.504613e-27 CTL_MUT
## Slc15a2 6.480667e-31 -0.7265252 0.171 0.054 1.944200e-27 CTL_MUT
## Ninj2 6.680432e-31 -1.6461812 0.150 0.030 2.004130e-27 CTL_MUT
## Ryr3 6.794115e-31 1.8166827 0.274 0.238 2.038235e-27 CTL_MUT
## S100a11 7.839589e-31 -5.0680491 0.150 0.021 2.351877e-27 CTL_MUT
## Gm20275 8.529606e-31 1.5070720 0.218 0.146 2.558882e-27 CTL_MUT
## AW047730 9.412309e-31 -3.0831652 0.178 0.078 2.823693e-27 CTL_MUT
## Gm15398 1.003272e-30 -4.5426000 0.176 0.135 3.009815e-27 CTL_MUT
## Selenop 1.142682e-30 1.0252060 0.237 0.227 3.428046e-27 CTL_MUT
## Ogn 1.264823e-30 -0.8102544 0.177 0.008 3.794468e-27 CTL_MUT
## Adgrb3 1.431938e-30 -1.7179249 0.484 0.430 4.295815e-27 CTL_MUT
## Robo2 1.607849e-30 -0.8778764 0.398 0.387 4.823546e-27 CTL_MUT
## Pde4d 2.136327e-30 -0.6727042 0.428 0.388 6.408981e-27 CTL_MUT
## 0610040J01Rik 2.458429e-30 3.3793156 0.169 0.033 7.375287e-27 CTL_MUT
## Gpx8 2.521001e-30 1.1424333 0.194 0.008 7.563002e-27 CTL_MUT
## Xkr4 2.763385e-30 -1.4399729 0.418 0.387 8.290156e-27 CTL_MUT
## Nckap1l 3.034157e-30 7.2935529 0.115 0.016 9.102471e-27 CTL_MUT
## Stard13 3.446488e-30 -7.5099016 0.174 0.081 1.033946e-26 CTL_MUT
## Dusp10 3.698130e-30 8.9249849 0.177 0.023 1.109439e-26 CTL_MUT
## Zfp804a 3.797701e-30 10.9349686 0.217 0.140 1.139310e-26 CTL_MUT
## Ssc4d 3.972968e-30 -1.8843487 0.149 0.003 1.191890e-26 CTL_MUT
## Npc2 4.145798e-30 1.2240473 0.210 0.150 1.243739e-26 CTL_MUT
## Esrrg 4.611573e-30 -4.0782526 0.256 0.196 1.383472e-26 CTL_MUT
## Acat3 5.601491e-30 -4.5875207 0.221 0.008 1.680447e-26 CTL_MUT
## Fam155a 5.947854e-30 -2.8098839 0.435 0.391 1.784356e-26 CTL_MUT
## Ptgs1 6.559904e-30 -2.4293773 0.145 0.026 1.967971e-26 CTL_MUT
## Kcnj16 7.168866e-30 9.0162131 0.182 0.036 2.150660e-26 CTL_MUT
## Serpinh1 8.196045e-30 -9.0861876 0.163 0.018 2.458813e-26 CTL_MUT
## N4bp2os 1.077114e-29 -4.9156462 0.153 0.003 3.231341e-26 CTL_MUT
## Tmem178b 1.382531e-29 -0.3051907 0.429 0.414 4.147593e-26 CTL_MUT
## Luzp2 1.408565e-29 -6.6864447 0.357 0.343 4.225695e-26 CTL_MUT
## Dnah3 1.433744e-29 -0.7627786 0.161 0.004 4.301232e-26 CTL_MUT
## Gm10754 1.677677e-29 -10.5133697 0.140 0.039 5.033032e-26 CTL_MUT
## Irak2 1.993798e-29 -10.0518211 0.150 0.080 5.981394e-26 CTL_MUT
## Homer1 2.621991e-29 -4.2971606 0.357 0.355 7.865972e-26 CTL_MUT
## Pdcd4 2.734951e-29 -0.6121542 0.232 0.278 8.204854e-26 CTL_MUT
## Pde8a 4.019868e-29 -2.3602797 0.170 0.047 1.205960e-25 CTL_MUT
## 2600014E21Rik 5.857980e-29 -5.4461010 0.155 0.019 1.757394e-25 CTL_MUT
## Chchd2 5.973696e-29 -0.2992042 0.361 0.410 1.792109e-25 CTL_MUT
## Kitl 6.465474e-29 -8.7535686 0.177 0.141 1.939642e-25 CTL_MUT
## Zic2 6.491196e-29 -1.2006941 0.145 0.011 1.947359e-25 CTL_MUT
## Cryba4 7.648295e-29 -2.4011463 0.157 0.006 2.294489e-25 CTL_MUT
## Dusp16 7.656992e-29 -5.0638073 0.177 0.062 2.297098e-25 CTL_MUT
## Islr 8.126659e-29 4.2953392 0.230 0.011 2.437998e-25 CTL_MUT
## Ubash3b 8.190443e-29 -2.3300558 0.165 0.087 2.457133e-25 CTL_MUT
## Thrb 8.873324e-29 -0.8966311 0.390 0.375 2.661997e-25 CTL_MUT
## Aplp1 8.920533e-29 -0.4719674 0.400 0.419 2.676160e-25 CTL_MUT
## Pola1 1.059569e-28 -9.3956805 0.202 0.067 3.178707e-25 CTL_MUT
## Psmb8 1.110239e-28 -2.1442857 0.180 0.008 3.330716e-25 CTL_MUT
## Trdn 1.159560e-28 -2.3306775 0.146 0.003 3.478680e-25 CTL_MUT
## Cysltr1 1.209666e-28 -2.0012774 0.109 0.005 3.628998e-25 CTL_MUT
## Myo16 1.471607e-28 1.9687465 0.204 0.160 4.414821e-25 CTL_MUT
## Pax6os1 1.554857e-28 -4.6732317 0.168 0.004 4.664572e-25 CTL_MUT
## Cd9 1.792180e-28 -2.4395067 0.208 0.126 5.376541e-25 CTL_MUT
## Gm13391 1.801357e-28 -0.8322879 0.126 0.009 5.404072e-25 CTL_MUT
## Col8a1 1.816125e-28 -3.9606391 0.168 0.012 5.448375e-25 CTL_MUT
## 1700024B18Rik 2.525411e-28 -0.4861407 0.191 0.085 7.576233e-25 CTL_MUT
## Aff1 3.145961e-28 -5.3834032 0.180 0.071 9.437883e-25 CTL_MUT
## Vgf 3.830021e-28 -5.9334030 0.170 0.188 1.149006e-24 CTL_MUT
## Dpp6 3.857753e-28 7.1656360 0.383 0.380 1.157326e-24 CTL_MUT
## Eda 4.079378e-28 -0.5439215 0.182 0.079 1.223813e-24 CTL_MUT
## C1qb 4.177782e-28 3.9986722 0.139 0.161 1.253335e-24 CTL_MUT
## 9530059O14Rik 5.349918e-28 -2.4411557 0.296 0.245 1.604976e-24 CTL_MUT
## Sox11 5.672832e-28 -2.7517569 0.162 0.125 1.701850e-24 CTL_MUT
## Pdk4 5.872409e-28 -2.7400658 0.195 0.007 1.761723e-24 CTL_MUT
## Tsc22d3 5.951379e-28 -0.4480425 0.222 0.162 1.785414e-24 CTL_MUT
## Cracr2b 6.217206e-28 -4.0967349 0.133 0.006 1.865162e-24 CTL_MUT
## Fgf12 6.587799e-28 -3.9191430 0.447 0.397 1.976340e-24 CTL_MUT
## Ptger1 7.190989e-28 -1.6180001 0.175 0.004 2.157297e-24 CTL_MUT
## Rbms1 7.257911e-28 -2.1059328 0.188 0.131 2.177373e-24 CTL_MUT
## Tal1 8.491032e-28 -1.5292997 0.137 0.005 2.547310e-24 CTL_MUT
## Sdk1 9.818150e-28 -2.4116666 0.281 0.225 2.945445e-24 CTL_MUT
## Egflam 1.046972e-27 -3.2852236 0.137 0.009 3.140917e-24 CTL_MUT
## Lef1 1.126768e-27 0.7179188 0.118 0.034 3.380305e-24 CTL_MUT
## Prr16 1.165905e-27 -0.5671056 0.302 0.283 3.497714e-24 CTL_MUT
## Ptprt 1.178136e-27 -11.7813441 0.392 0.385 3.534408e-24 CTL_MUT
## Oxr1 1.388183e-27 1.4390002 0.418 0.402 4.164548e-24 CTL_MUT
## Col4a2 1.558122e-27 -8.7838669 0.186 0.111 4.674365e-24 CTL_MUT
## 9530026P05Rik 1.641245e-27 -4.1678697 0.121 0.042 4.923734e-24 CTL_MUT
## Ak7 1.661701e-27 -1.7628216 0.137 0.003 4.985103e-24 CTL_MUT
## Tmem108 1.970674e-27 2.3171614 0.276 0.237 5.912021e-24 CTL_MUT
## Nudt4 2.085319e-27 1.7328423 0.221 0.231 6.255956e-24 CTL_MUT
## Smc2 2.126035e-27 -8.4779840 0.188 0.035 6.378106e-24 CTL_MUT
## Nppa 2.209306e-27 -3.2821971 0.119 0.001 6.627918e-24 CTL_MUT
## Adamts2 2.401090e-27 -2.2952024 0.183 0.035 7.203271e-24 CTL_MUT
## Mt3 2.738827e-27 0.8087940 0.369 0.419 8.216482e-24 CTL_MUT
## Tmem52 2.759871e-27 -2.4567238 0.213 0.010 8.279614e-24 CTL_MUT
## Tnfaip8 2.895462e-27 -8.0614720 0.194 0.020 8.686385e-24 CTL_MUT
## Rbfox1 3.622110e-27 -3.8460474 0.426 0.381 1.086633e-23 CTL_MUT
## Col27a1 3.737254e-27 -3.3019607 0.160 0.014 1.121176e-23 CTL_MUT
## Gjc3 4.138777e-27 -1.2170698 0.185 0.085 1.241633e-23 CTL_MUT
## 1700094J05Rik 4.188858e-27 0.4307063 0.114 0.003 1.256657e-23 CTL_MUT
## Spon1 4.411648e-27 -2.3284074 0.256 0.161 1.323494e-23 CTL_MUT
## Hist1h2ac 5.100793e-27 -5.7515238 0.167 0.006 1.530238e-23 CTL_MUT
## Hk2 5.525042e-27 -2.3762497 0.130 0.020 1.657513e-23 CTL_MUT
## D7Ertd443e 5.882341e-27 -6.7378949 0.129 0.042 1.764702e-23 CTL_MUT
## Dbi 5.989874e-27 -3.9380030 0.394 0.373 1.796962e-23 CTL_MUT
## 4933406I18Rik 7.295391e-27 -3.7374909 0.216 0.138 2.188617e-23 CTL_MUT
## Trpm3 8.526804e-27 -0.8620214 0.310 0.297 2.558041e-23 CTL_MUT
## Picalm 9.292505e-27 1.1672988 0.280 0.240 2.787751e-23 CTL_MUT
## Atp1b2 1.054505e-26 1.0404293 0.263 0.278 3.163514e-23 CTL_MUT
## Il10rb 1.412790e-26 -1.4851856 0.140 0.011 4.238370e-23 CTL_MUT
## Opcml 1.597574e-26 -1.3606652 0.457 0.407 4.792722e-23 CTL_MUT
## Abcc4 1.631274e-26 -3.5196952 0.133 0.054 4.893822e-23 CTL_MUT
## Tmem164 1.749555e-26 4.1994736 0.161 0.105 5.248666e-23 CTL_MUT
## Gli2 1.770452e-26 -1.7202082 0.128 0.034 5.311356e-23 CTL_MUT
## Col4a5 1.963971e-26 2.1053957 0.175 0.010 5.891912e-23 CTL_MUT
## Cadm1 2.124274e-26 -0.5094351 0.428 0.414 6.372823e-23 CTL_MUT
## Gm12296 2.143902e-26 2.2240350 0.156 0.023 6.431707e-23 CTL_MUT
## Slc1a5 2.186630e-26 -1.6045140 0.115 0.004 6.559890e-23 CTL_MUT
## Pmp22 2.553200e-26 1.4410516 0.164 0.053 7.659601e-23 CTL_MUT
## Icam1 2.735612e-26 -5.0299192 0.112 0.006 8.206835e-23 CTL_MUT
## Blnk 2.832869e-26 0.2889003 0.148 0.039 8.498607e-23 CTL_MUT
## Rgs1 3.118415e-26 -1.4347503 0.102 0.011 9.355244e-23 CTL_MUT
## C1qa 3.520081e-26 -0.9699168 0.135 0.165 1.056024e-22 CTL_MUT
## B3galt5 3.645363e-26 0.3931074 0.175 0.029 1.093609e-22 CTL_MUT
## Fhod3 3.750160e-26 -1.1286635 0.284 0.275 1.125048e-22 CTL_MUT
## 4930403P22Rik 3.758730e-26 -1.0228749 0.117 0.003 1.127619e-22 CTL_MUT
## Dnmbp 4.556062e-26 -21.7386799 0.189 0.056 1.366819e-22 CTL_MUT
## Sall1 5.241114e-26 -5.3411421 0.164 0.027 1.572334e-22 CTL_MUT
## Jund 5.482490e-26 0.6860312 0.303 0.328 1.644747e-22 CTL_MUT
## Gm34838 5.561932e-26 -0.6674860 0.191 0.000 1.668580e-22 CTL_MUT
## Slc1a3 6.100937e-26 -3.8015341 0.338 0.347 1.830281e-22 CTL_MUT
## Prkch 6.665982e-26 -5.2444271 0.121 0.025 1.999795e-22 CTL_MUT
## Epha7 7.121692e-26 -1.3800916 0.259 0.200 2.136508e-22 CTL_MUT
## Glul 7.290839e-26 -1.8500462 0.402 0.402 2.187252e-22 CTL_MUT
## Gm11867 9.389439e-26 -6.1905918 0.218 0.014 2.816832e-22 CTL_MUT
## Wfdc18 1.064342e-25 -5.5324767 0.162 0.018 3.193026e-22 CTL_MUT
## P2rx7 1.097861e-25 -2.5944543 0.173 0.021 3.293582e-22 CTL_MUT
## Rbpms 1.130591e-25 -6.9659011 0.100 0.026 3.391773e-22 CTL_MUT
## Zmat4 1.141986e-25 -3.7393158 0.256 0.236 3.425959e-22 CTL_MUT
## Hmgb3 1.215230e-25 5.2332085 0.131 0.065 3.645690e-22 CTL_MUT
## Csmd1 1.302732e-25 -1.5184869 0.505 0.436 3.908195e-22 CTL_MUT
## Apobec1 1.506723e-25 -0.5968120 0.165 0.008 4.520169e-22 CTL_MUT
## Stmn1 1.527800e-25 -0.5239737 0.303 0.360 4.583401e-22 CTL_MUT
## Egfl8 1.574182e-25 -0.9476565 0.195 0.004 4.722547e-22 CTL_MUT
## Ace 1.857674e-25 -1.1263158 0.162 0.003 5.573022e-22 CTL_MUT
## Ubb 1.873593e-25 -0.3858212 0.339 0.390 5.620779e-22 CTL_MUT
## Cntnap4 1.911530e-25 -5.1413741 0.213 0.121 5.734591e-22 CTL_MUT
## Rplp0 2.061316e-25 -2.7744825 0.376 0.380 6.183949e-22 CTL_MUT
## Epb41l4a 2.219214e-25 3.3689977 0.213 0.012 6.657643e-22 CTL_MUT
## Slc5a11 2.284518e-25 -2.2654257 0.103 0.002 6.853553e-22 CTL_MUT
## Gm2164 2.337750e-25 -0.4412624 0.144 0.057 7.013249e-22 CTL_MUT
## Kank1 2.343571e-25 -0.2506121 0.156 0.068 7.030713e-22 CTL_MUT
## Cntnap5b 2.382046e-25 -2.9281987 0.248 0.150 7.146139e-22 CTL_MUT
## Ighm 2.518663e-25 -3.0388186 0.230 0.016 7.555990e-22 CTL_MUT
## Gstm5 2.572680e-25 0.2643456 0.397 0.412 7.718039e-22 CTL_MUT
## 9330158H04Rik 3.632836e-25 1.4115718 0.212 0.008 1.089851e-21 CTL_MUT
## Has2os 3.683640e-25 -5.2956495 0.133 0.005 1.105092e-21 CTL_MUT
## Shc4 3.819351e-25 -4.8255488 0.151 0.020 1.145805e-21 CTL_MUT
## Dctn3 4.017508e-25 -0.9249207 0.300 0.348 1.205252e-21 CTL_MUT
## Gm29994 4.144929e-25 9.6912189 0.222 0.005 1.243479e-21 CTL_MUT
## Atp5g3 4.320979e-25 -0.4238937 0.367 0.406 1.296294e-21 CTL_MUT
## Acta2 6.317508e-25 -0.7001529 0.133 0.007 1.895252e-21 CTL_MUT
## Ms4a6d 6.417651e-25 -2.7883532 0.104 0.005 1.925295e-21 CTL_MUT
## Lrtm1 6.515250e-25 -3.4698272 0.147 0.051 1.954575e-21 CTL_MUT
## C230038L03Rik 6.608420e-25 -0.3773226 0.156 0.068 1.982526e-21 CTL_MUT
## Gm13986 6.684452e-25 -2.0478439 0.115 0.002 2.005336e-21 CTL_MUT
## Cdh13 7.310842e-25 6.4922316 0.290 0.269 2.193253e-21 CTL_MUT
## Cks1b 7.435133e-25 -2.6738329 0.152 0.010 2.230540e-21 CTL_MUT
## Bfsp2 8.433157e-25 1.6059350 0.169 0.019 2.529947e-21 CTL_MUT
## Ano3 8.837407e-25 -0.5105257 0.369 0.365 2.651222e-21 CTL_MUT
## A830036E02Rik 9.335211e-25 -4.0697135 0.144 0.095 2.800563e-21 CTL_MUT
## Parm1 9.617564e-25 -3.3360589 0.177 0.072 2.885269e-21 CTL_MUT
## Ecrg4 1.129431e-24 -3.2490397 0.130 0.005 3.388292e-21 CTL_MUT
## Cx3cr1 1.137419e-24 -1.3038406 0.106 0.098 3.412257e-21 CTL_MUT
## Ppp1r14b 1.389008e-24 0.4912357 0.171 0.131 4.167025e-21 CTL_MUT
## Clmn 1.417953e-24 -1.9160635 0.226 0.166 4.253859e-21 CTL_MUT
## Nr3c2 1.752012e-24 0.3699218 0.203 0.156 5.256036e-21 CTL_MUT
## Atp10b 2.249766e-24 -2.2369260 0.126 0.008 6.749297e-21 CTL_MUT
## Il1rapl1 2.588951e-24 0.7463955 0.441 0.408 7.766852e-21 CTL_MUT
## Ucp3 2.624497e-24 -2.9084649 0.156 0.002 7.873490e-21 CTL_MUT
## Csf1r 2.879161e-24 4.0280875 0.102 0.086 8.637482e-21 CTL_MUT
## Etl4 2.921608e-24 -4.7486842 0.371 0.347 8.764824e-21 CTL_MUT
## Prkca 3.335299e-24 -3.8874358 0.381 0.373 1.000590e-20 CTL_MUT
## Il1b 3.381771e-24 -1.4665712 0.145 0.004 1.014531e-20 CTL_MUT
## Mdfic 3.498206e-24 -2.1140826 0.142 0.006 1.049462e-20 CTL_MUT
## Plin5 4.481896e-24 -1.5469795 0.133 0.002 1.344569e-20 CTL_MUT
## 9930111J21Rik2 5.275210e-24 4.0548751 0.120 0.009 1.582563e-20 CTL_MUT
## Gpcpd1 5.544715e-24 2.8269277 0.253 0.230 1.663414e-20 CTL_MUT
## Syt2 6.099062e-24 -7.5848413 0.216 0.016 1.829719e-20 CTL_MUT
## Plcb4 7.125705e-24 2.8220184 0.304 0.262 2.137711e-20 CTL_MUT
## Filip1l 7.186826e-24 -8.2061666 0.205 0.047 2.156048e-20 CTL_MUT
## Gm16346 8.572334e-24 -4.4158041 0.131 0.002 2.571700e-20 CTL_MUT
## C1ql1 8.841379e-24 0.8725105 0.126 0.020 2.652414e-20 CTL_MUT
## Cadm2 9.421155e-24 -2.1908063 0.465 0.426 2.826347e-20 CTL_MUT
## Gm13861 9.574910e-24 -0.4621006 0.110 0.005 2.872473e-20 CTL_MUT
## Adamtsl1 1.125009e-23 -0.6562315 0.210 0.066 3.375027e-20 CTL_MUT
## Btbd11 1.252009e-23 -3.8954697 0.100 0.044 3.756026e-20 CTL_MUT
## Tox 1.411049e-23 -3.6654823 0.321 0.267 4.233147e-20 CTL_MUT
## Gm15155 1.636847e-23 -1.0035998 0.229 0.135 4.910541e-20 CTL_MUT
## Npsr1 1.661176e-23 -2.4101823 0.165 0.036 4.983529e-20 CTL_MUT
## Hspa8 1.689793e-23 -0.4175162 0.356 0.403 5.069379e-20 CTL_MUT
## Pitpnc1 1.812606e-23 -2.7618055 0.261 0.233 5.437817e-20 CTL_MUT
## Auts2 1.888825e-23 -0.2992767 0.453 0.420 5.666476e-20 CTL_MUT
## Gm2516 1.940032e-23 -2.2589800 0.101 0.005 5.820097e-20 CTL_MUT
## Tmem229a 2.112224e-23 -0.3050595 0.187 0.060 6.336671e-20 CTL_MUT
## Sytl5 2.276105e-23 7.6913012 0.136 0.012 6.828315e-20 CTL_MUT
## Galnt18 2.512504e-23 -0.3254620 0.292 0.238 7.537512e-20 CTL_MUT
## Foxc1 2.930981e-23 0.6466896 0.106 0.013 8.792943e-20 CTL_MUT
## Arx 3.004507e-23 -2.4466772 0.158 0.024 9.013522e-20 CTL_MUT
## Dpp10 3.115423e-23 -1.1376962 0.442 0.391 9.346269e-20 CTL_MUT
## Celrr 3.473474e-23 11.5929715 0.149 0.037 1.042042e-19 CTL_MUT
## Macrod2 4.387069e-23 -0.4726000 0.440 0.407 1.316121e-19 CTL_MUT
## Gm32913 4.444691e-23 -2.5101313 0.149 0.002 1.333407e-19 CTL_MUT
## H2-DMb1 4.449718e-23 1.0007546 0.139 0.003 1.334915e-19 CTL_MUT
## Lima1 4.919541e-23 -0.5153548 0.170 0.059 1.475862e-19 CTL_MUT
## Ifitm1 4.965423e-23 0.4912838 0.102 0.018 1.489627e-19 CTL_MUT
## Npas3 5.358234e-23 -4.9962435 0.265 0.260 1.607470e-19 CTL_MUT
## Gm20754 5.756729e-23 6.0035299 0.289 0.247 1.727019e-19 CTL_MUT
## Cspg5 5.791287e-23 0.8125311 0.323 0.353 1.737386e-19 CTL_MUT
## Efna5 5.925484e-23 0.8230531 0.307 0.282 1.777645e-19 CTL_MUT
## Hsp90ab1 6.062118e-23 -0.3540077 0.367 0.424 1.818635e-19 CTL_MUT
## Hapln1 6.448716e-23 5.6996516 0.165 0.054 1.934615e-19 CTL_MUT
## Hist2h3c1 7.327342e-23 3.6253606 0.204 0.004 2.198202e-19 CTL_MUT
## Kcnq3 8.418124e-23 -0.3239051 0.427 0.402 2.525437e-19 CTL_MUT
## Vav3 8.457940e-23 -1.4090580 0.165 0.064 2.537382e-19 CTL_MUT
## Gm32250 8.501786e-23 0.6070597 0.183 0.124 2.550536e-19 CTL_MUT
## Birc5 9.010597e-23 1.7559673 0.124 0.010 2.703179e-19 CTL_MUT
## C4b 9.219641e-23 1.0138733 0.170 0.007 2.765892e-19 CTL_MUT
## Cgnl1 1.110794e-22 0.6080632 0.148 0.020 3.332383e-19 CTL_MUT
## Greb1 1.178212e-22 -7.8851322 0.167 0.010 3.534637e-19 CTL_MUT
## Gm39185 1.334994e-22 -4.7222548 0.143 0.006 4.004981e-19 CTL_MUT
## Id1 1.392185e-22 1.2221912 0.131 0.072 4.176554e-19 CTL_MUT
## Hmgcs1 1.396786e-22 3.4518006 0.256 0.248 4.190359e-19 CTL_MUT
## Klf4 1.737315e-22 -5.3322734 0.120 0.039 5.211944e-19 CTL_MUT
## Fermt2 1.872684e-22 -0.5080473 0.270 0.199 5.618053e-19 CTL_MUT
## Timp1 1.879909e-22 -0.5401828 0.137 0.002 5.639728e-19 CTL_MUT
## Eif1 1.885893e-22 0.5319898 0.361 0.408 5.657678e-19 CTL_MUT
## Mpped2 1.960245e-22 6.1894131 0.279 0.252 5.880734e-19 CTL_MUT
## Grap 1.983811e-22 -7.1588278 0.157 0.008 5.951434e-19 CTL_MUT
## Cfh 2.060276e-22 6.9248535 0.128 0.027 6.180828e-19 CTL_MUT
## Naalad2 2.206048e-22 -7.3537290 0.109 0.004 6.618145e-19 CTL_MUT
## Ndp 2.455076e-22 -1.7892851 0.212 0.009 7.365227e-19 CTL_MUT
## Tcim 2.543838e-22 1.9690318 0.192 0.009 7.631513e-19 CTL_MUT
## Irf8 2.568219e-22 7.8989515 0.139 0.013 7.704656e-19 CTL_MUT
## Gm47936 2.921100e-22 6.3589231 0.173 0.003 8.763301e-19 CTL_MUT
## Map1lc3a 3.180071e-22 -0.7757863 0.356 0.406 9.540214e-19 CTL_MUT
## Mdh1 3.280949e-22 -0.4501873 0.350 0.401 9.842846e-19 CTL_MUT
## Nrip3 3.373138e-22 1.9508909 0.173 0.113 1.011942e-18 CTL_MUT
## Vwf 3.883525e-22 -3.5710613 0.140 0.007 1.165058e-18 CTL_MUT
## Lsamp 3.885111e-22 1.6283277 0.404 0.374 1.165533e-18 CTL_MUT
## Melk 4.194840e-22 1.0142041 0.156 0.006 1.258452e-18 CTL_MUT
## Gata2 5.237360e-22 -1.4679769 0.107 0.008 1.571208e-18 CTL_MUT
## Abhd15 5.248026e-22 -3.5023848 0.181 0.011 1.574408e-18 CTL_MUT
## Gap43 5.452480e-22 0.8879372 0.310 0.359 1.635744e-18 CTL_MUT
## Pou6f2 5.829014e-22 -2.3387977 0.168 0.083 1.748704e-18 CTL_MUT
## Dkk2 6.141745e-22 5.6432004 0.156 0.008 1.842524e-18 CTL_MUT
## Mal 6.145613e-22 2.7614657 0.190 0.145 1.843684e-18 CTL_MUT
## Clic5 6.908830e-22 -8.3292237 0.108 0.027 2.072649e-18 CTL_MUT
## Trip13 8.641604e-22 -0.8465370 0.123 0.003 2.592481e-18 CTL_MUT
## Ccn2 9.358806e-22 -3.7541423 0.140 0.016 2.807642e-18 CTL_MUT
## Utrn 9.512964e-22 -6.8446796 0.198 0.158 2.853889e-18 CTL_MUT
## Pard3 1.014074e-21 -0.3774208 0.224 0.156 3.042221e-18 CTL_MUT
## Lcp1 1.082337e-21 7.2502689 0.129 0.025 3.247010e-18 CTL_MUT
## Golim4 1.162540e-21 1.1794071 0.166 0.057 3.487620e-18 CTL_MUT
## Elavl2 1.338477e-21 -3.8761146 0.287 0.272 4.015430e-18 CTL_MUT
## Elf1 1.423169e-21 -7.0227302 0.173 0.044 4.269506e-18 CTL_MUT
## Plcb1 1.484776e-21 -0.4061440 0.450 0.412 4.454327e-18 CTL_MUT
## Gm26619 1.629510e-21 0.2979287 0.191 0.004 4.888531e-18 CTL_MUT
## Kcnh1 1.660547e-21 0.2800324 0.309 0.259 4.981642e-18 CTL_MUT
## Kcnd2 1.911459e-21 1.4092514 0.448 0.399 5.734376e-18 CTL_MUT
## Slc44a5 2.058841e-21 4.0202799 0.178 0.090 6.176522e-18 CTL_MUT
## AA387883 2.346557e-21 -7.0951498 0.142 0.011 7.039672e-18 CTL_MUT
## Fcgr2b 3.828632e-21 -1.8893814 0.153 0.006 1.148590e-17 CTL_MUT
## Dach2 3.840659e-21 -1.4038051 0.224 0.009 1.152198e-17 CTL_MUT
## Pvalb 4.051596e-21 1.7128060 0.189 0.031 1.215479e-17 CTL_MUT
## Tril 4.456100e-21 -1.1715468 0.154 0.064 1.336830e-17 CTL_MUT
## Epha6 4.555725e-21 1.4203145 0.330 0.322 1.366717e-17 CTL_MUT
## Gria1 4.683240e-21 -0.6940047 0.407 0.381 1.404972e-17 CTL_MUT
## Ms4a6c 5.561190e-21 -1.3638237 0.162 0.006 1.668357e-17 CTL_MUT
## Ascl1 7.475509e-21 -2.7397584 0.151 0.013 2.242653e-17 CTL_MUT
## 6030407O03Rik 8.232507e-21 -3.0747873 0.108 0.008 2.469752e-17 CTL_MUT
## Zfand4 8.365842e-21 -0.6663103 0.192 0.062 2.509753e-17 CTL_MUT
## Cdh12 8.407398e-21 6.3164635 0.342 0.338 2.522220e-17 CTL_MUT
## Pcdh7 8.471150e-21 4.9451054 0.421 0.396 2.541345e-17 CTL_MUT
## Arl5c 8.678547e-21 -5.7332285 0.120 0.002 2.603564e-17 CTL_MUT
## A330008L17Rik 1.064698e-20 -4.2392547 0.167 0.108 3.194094e-17 CTL_MUT
## Sst 1.197977e-20 -0.4301671 0.255 0.193 3.593932e-17 CTL_MUT
## Atpif1 1.347712e-20 -0.3335678 0.350 0.390 4.043137e-17 CTL_MUT
## Hmgn1 1.349456e-20 10.7118700 0.197 0.201 4.048368e-17 CTL_MUT
## Nrg3 1.390281e-20 -1.0317517 0.492 0.433 4.170844e-17 CTL_MUT
## Cyp2j12 1.445619e-20 -7.4932642 0.115 0.011 4.336857e-17 CTL_MUT
## Epas1 1.781678e-20 -1.6875836 0.152 0.114 5.345033e-17 CTL_MUT
## C130073E24Rik 2.066623e-20 -1.7109673 0.136 0.023 6.199869e-17 CTL_MUT
## Carhsp1 2.766467e-20 -8.0050637 0.173 0.057 8.299402e-17 CTL_MUT
## Nlgn1 2.811820e-20 -0.6991495 0.464 0.419 8.435459e-17 CTL_MUT
## Nyap2 2.852790e-20 11.0086994 0.318 0.319 8.558370e-17 CTL_MUT
## Nrxn3 2.862161e-20 -2.7934317 0.440 0.395 8.586483e-17 CTL_MUT
## Plpp3 2.937611e-20 2.3975462 0.284 0.261 8.812833e-17 CTL_MUT
## Bcl11b 2.966204e-20 -3.5573880 0.212 0.147 8.898612e-17 CTL_MUT
## Hint1 3.043697e-20 -0.2909972 0.377 0.429 9.131090e-17 CTL_MUT
## Prelid2 3.123340e-20 -0.7009454 0.121 0.003 9.370020e-17 CTL_MUT
## H2afv 3.203353e-20 -11.5352089 0.191 0.157 9.610059e-17 CTL_MUT
## Htra3 3.289101e-20 -2.2996815 0.144 0.004 9.867303e-17 CTL_MUT
## Trhde 3.483025e-20 4.9163431 0.234 0.203 1.044908e-16 CTL_MUT
## Slco1b2 3.716610e-20 -1.3124395 0.145 0.006 1.114983e-16 CTL_MUT
## Hmgn2 3.787802e-20 0.3022801 0.151 0.113 1.136341e-16 CTL_MUT
## Crybb1 3.825481e-20 9.7470097 0.125 0.030 1.147644e-16 CTL_MUT
## Art3 4.014802e-20 -2.1312254 0.139 0.010 1.204441e-16 CTL_MUT
## Arhgef5 4.346080e-20 -1.2425452 0.136 0.005 1.303824e-16 CTL_MUT
## Maml2 4.443624e-20 5.1133326 0.237 0.191 1.333087e-16 CTL_MUT
## Mif 4.888777e-20 -1.0012215 0.367 0.406 1.466633e-16 CTL_MUT
## Gm16201 5.462110e-20 -1.3392319 0.103 0.003 1.638633e-16 CTL_MUT
## Insm1 5.609043e-20 -1.2724815 0.172 0.007 1.682713e-16 CTL_MUT
## Mybpc1 6.090687e-20 -0.2716674 0.116 0.005 1.827206e-16 CTL_MUT
## Edn1 6.242082e-20 -3.8745736 0.118 0.019 1.872625e-16 CTL_MUT
## Gm49708 6.990743e-20 -10.7723688 0.157 0.018 2.097223e-16 CTL_MUT
## Cebpa 7.177700e-20 -0.5747036 0.176 0.009 2.153310e-16 CTL_MUT
## Cnn2 7.181776e-20 -3.2053631 0.147 0.008 2.154533e-16 CTL_MUT
## Frmpd1 7.733831e-20 -1.6501536 0.116 0.037 2.320149e-16 CTL_MUT
## Rims1 8.284031e-20 -0.2602178 0.437 0.399 2.485209e-16 CTL_MUT
## Peli1 1.033855e-19 -3.2748432 0.250 0.204 3.101564e-16 CTL_MUT
## Sod3 1.110435e-19 2.6640165 0.143 0.011 3.331305e-16 CTL_MUT
## Castor1 1.216743e-19 1.2821451 0.184 0.012 3.650229e-16 CTL_MUT
## Epor 1.567634e-19 1.2234137 0.125 0.003 4.702902e-16 CTL_MUT
## C1qc 1.666997e-19 0.3385914 0.112 0.110 5.000991e-16 CTL_MUT
## 4930587E11Rik 1.867582e-19 -5.8834664 0.166 0.066 5.602746e-16 CTL_MUT
## Cntnap5c 2.010886e-19 -0.5701770 0.139 0.105 6.032659e-16 CTL_MUT
## Srgn 2.076202e-19 8.5591028 0.122 0.037 6.228605e-16 CTL_MUT
## 2810468N07Rik 2.112585e-19 -1.9747170 0.178 0.062 6.337755e-16 CTL_MUT
## 3300002A11Rik 2.333321e-19 -3.9759484 0.167 0.003 6.999962e-16 CTL_MUT
## Acss1 2.557752e-19 2.1390878 0.169 0.065 7.673255e-16 CTL_MUT
## Gm16351 2.722578e-19 -2.4249497 0.180 0.054 8.167734e-16 CTL_MUT
## Tnni1 3.086261e-19 -3.8251534 0.110 0.021 9.258784e-16 CTL_MUT
## Gm38287 3.203255e-19 -0.8813538 0.157 0.021 9.609766e-16 CTL_MUT
## Penk 3.609577e-19 -1.5103973 0.141 0.022 1.082873e-15 CTL_MUT
## Fmn1 3.645443e-19 -0.4790718 0.218 0.146 1.093633e-15 CTL_MUT
## Btbd16 4.386671e-19 -6.7878567 0.135 0.008 1.316001e-15 CTL_MUT
## Bgn 4.828926e-19 -1.0878671 0.126 0.010 1.448678e-15 CTL_MUT
## Crip2 5.905217e-19 3.2814851 0.185 0.251 1.771565e-15 CTL_MUT
## Hdac9 5.920171e-19 -0.5677250 0.356 0.346 1.776051e-15 CTL_MUT
## Dlgap2 6.266816e-19 -1.6426900 0.424 0.390 1.880045e-15 CTL_MUT
## Col11a1 6.321973e-19 -3.6640140 0.163 0.018 1.896592e-15 CTL_MUT
## Acaa1b 6.868102e-19 -1.1728273 0.158 0.002 2.060431e-15 CTL_MUT
## Fcer1g 7.677929e-19 3.5787565 0.109 0.085 2.303379e-15 CTL_MUT
## Htr1f 7.839400e-19 -1.9833018 0.235 0.145 2.351820e-15 CTL_MUT
## Cpa6 8.379379e-19 3.1781169 0.186 0.029 2.513814e-15 CTL_MUT
## Hmox1 9.021332e-19 -1.0851166 0.174 0.007 2.706400e-15 CTL_MUT
## F3 9.678580e-19 8.1639218 0.143 0.073 2.903574e-15 CTL_MUT
## Ldb2 9.990051e-19 0.8046666 0.336 0.304 2.997015e-15 CTL_MUT
## Ggt1 1.271874e-18 -5.2046572 0.116 0.003 3.815623e-15 CTL_MUT
## Ptgds 1.379897e-18 1.8606734 0.166 0.155 4.139690e-15 CTL_MUT
## Tent5a 1.565097e-18 -1.2893503 0.165 0.018 4.695292e-15 CTL_MUT
## Ptprm 1.569469e-18 -2.0464057 0.237 0.176 4.708407e-15 CTL_MUT
## Stard5 1.890982e-18 -0.3769682 0.190 0.021 5.672947e-15 CTL_MUT
## Flt4 2.074512e-18 -1.8670234 0.109 0.005 6.223537e-15 CTL_MUT
## Scn9a 2.097251e-18 -4.1385071 0.155 0.027 6.291754e-15 CTL_MUT
## Esam 2.113201e-18 8.0127087 0.110 0.032 6.339604e-15 CTL_MUT
## Gm35552 2.360280e-18 -3.5342420 0.124 0.015 7.080841e-15 CTL_MUT
## 4930555F03Rik 2.638018e-18 -3.3532758 0.140 0.015 7.914055e-15 CTL_MUT
## Unc13c 2.867431e-18 0.9874705 0.166 0.068 8.602293e-15 CTL_MUT
## Fabp7 3.074403e-18 0.3626188 0.223 0.130 9.223210e-15 CTL_MUT
## Nuf2 3.437700e-18 -4.5518614 0.176 0.006 1.031310e-14 CTL_MUT
## Grm1 4.069312e-18 1.0530235 0.270 0.242 1.220794e-14 CTL_MUT
## Scn5a 4.313873e-18 -1.6783454 0.101 0.002 1.294162e-14 CTL_MUT
## A2ml1 4.359882e-18 5.7244644 0.126 0.064 1.307965e-14 CTL_MUT
## Soga1 4.700064e-18 -8.4843640 0.191 0.038 1.410019e-14 CTL_MUT
## Mgst3 4.927262e-18 0.5867413 0.220 0.251 1.478178e-14 CTL_MUT
## Mafb 5.077931e-18 -3.0250670 0.138 0.042 1.523379e-14 CTL_MUT
## Cldn10 5.280413e-18 -6.6308708 0.172 0.099 1.584124e-14 CTL_MUT
## 9630028H03Rik 5.408374e-18 -2.1790676 0.227 0.161 1.622512e-14 CTL_MUT
## Cftr 5.434975e-18 -8.4392204 0.115 0.004 1.630492e-14 CTL_MUT
## Nrg3os 8.633032e-18 0.8929370 0.308 0.297 2.589910e-14 CTL_MUT
## Fgd5 8.868972e-18 0.6896102 0.110 0.012 2.660692e-14 CTL_MUT
## Gm816 9.182712e-18 -2.5355924 0.115 0.002 2.754814e-14 CTL_MUT
## Cox6a2 9.248194e-18 -3.8054650 0.165 0.027 2.774458e-14 CTL_MUT
## Egfem1 1.162146e-17 -3.5368880 0.336 0.326 3.486437e-14 CTL_MUT
## Fermt3 1.332917e-17 3.6514467 0.122 0.013 3.998750e-14 CTL_MUT
## Eps8 1.511892e-17 -2.8867126 0.155 0.074 4.535675e-14 CTL_MUT
## Dgkg 1.525920e-17 -1.3117894 0.235 0.170 4.577759e-14 CTL_MUT
## Trim56 1.822197e-17 -0.5776163 0.235 0.007 5.466591e-14 CTL_MUT
## Gldc 1.833751e-17 -5.6044641 0.156 0.034 5.501254e-14 CTL_MUT
## Mt2 1.921209e-17 -2.2211885 0.340 0.375 5.763627e-14 CTL_MUT
## S100a1 1.951594e-17 -0.7715873 0.305 0.259 5.854781e-14 CTL_MUT
## Gm33680 2.489886e-17 -1.3414136 0.162 0.012 7.469659e-14 CTL_MUT
## Col5a2 2.672066e-17 5.7389008 0.194 0.009 8.016198e-14 CTL_MUT
## Fgf14 2.817453e-17 -0.2962053 0.472 0.426 8.452359e-14 CTL_MUT
## Ntrk3 3.302255e-17 -0.4680513 0.394 0.385 9.906766e-14 CTL_MUT
## Spsb4 3.447889e-17 -0.4095910 0.150 0.005 1.034367e-13 CTL_MUT
## Dab2 3.789408e-17 2.4529620 0.138 0.021 1.136822e-13 CTL_MUT
## Mgst1 4.193728e-17 8.0451669 0.222 0.015 1.258118e-13 CTL_MUT
## Appl2 4.777337e-17 2.3067689 0.162 0.095 1.433201e-13 CTL_MUT
## Csrp2 4.963662e-17 5.7610220 0.135 0.029 1.489099e-13 CTL_MUT
## Sall3 6.560893e-17 2.7156706 0.153 0.030 1.968268e-13 CTL_MUT
## Selenom 6.575170e-17 -3.5770110 0.320 0.332 1.972551e-13 CTL_MUT
## Ctsl 6.606067e-17 -0.9175227 0.231 0.217 1.981820e-13 CTL_MUT
## Fgf13 6.909641e-17 -1.8082757 0.245 0.251 2.072892e-13 CTL_MUT
## Rfx3 7.376821e-17 1.1735057 0.326 0.317 2.213046e-13 CTL_MUT
## Mei4 8.163257e-17 -13.8960388 0.154 0.050 2.448977e-13 CTL_MUT
## Zeb1 8.174833e-17 1.2693657 0.309 0.264 2.452450e-13 CTL_MUT
## Ftl1 8.451917e-17 0.5216139 0.416 0.440 2.535575e-13 CTL_MUT
## Slc38a11 9.283090e-17 1.1863230 0.102 0.008 2.784927e-13 CTL_MUT
## Apln 1.117160e-16 -1.1617992 0.209 0.022 3.351481e-13 CTL_MUT
## Kcnk2 1.140862e-16 1.4805013 0.245 0.260 3.422585e-13 CTL_MUT
## Gm20743 1.217330e-16 -3.2989880 0.218 0.006 3.651989e-13 CTL_MUT
## Slc6a16 1.219458e-16 -6.3126919 0.173 0.004 3.658375e-13 CTL_MUT
## Rftn2 1.330108e-16 -4.9516865 0.160 0.043 3.990325e-13 CTL_MUT
## Sgk2 1.384745e-16 -5.4232102 0.128 0.007 4.154236e-13 CTL_MUT
## Gria4 1.551478e-16 18.5981266 0.407 0.396 4.654435e-13 CTL_MUT
## Lmntd1 1.588855e-16 -1.0751791 0.144 0.005 4.766565e-13 CTL_MUT
## Gm28376 1.647072e-16 6.2282002 0.257 0.233 4.941215e-13 CTL_MUT
## 9130019P16Rik 1.868439e-16 3.0636309 0.151 0.022 5.605317e-13 CTL_MUT
## Gm10863 1.943460e-16 -7.2091412 0.116 0.010 5.830380e-13 CTL_MUT
## Negr1 1.992074e-16 -0.3335078 0.430 0.403 5.976221e-13 CTL_MUT
## Cyba 2.052213e-16 -8.9039205 0.118 0.047 6.156638e-13 CTL_MUT
## Phactr2 2.072444e-16 -2.1645485 0.195 0.070 6.217332e-13 CTL_MUT
## Pcsk2 2.210893e-16 -0.4263843 0.383 0.414 6.632680e-13 CTL_MUT
## Dlx2 2.462464e-16 -5.0719878 0.128 0.010 7.387393e-13 CTL_MUT
## Nostrin 2.834719e-16 -0.3269985 0.105 0.035 8.504157e-13 CTL_MUT
## Nxn 2.900945e-16 -5.9560112 0.154 0.068 8.702834e-13 CTL_MUT
## Slc4a4 2.996675e-16 11.3595245 0.343 0.334 8.990024e-13 CTL_MUT
## Ttf2 3.121531e-16 -0.3069852 0.150 0.003 9.364592e-13 CTL_MUT
## Gm17690 3.620384e-16 0.5323165 0.147 0.002 1.086115e-12 CTL_MUT
## Svil 3.696632e-16 -3.5113714 0.156 0.059 1.108990e-12 CTL_MUT
## 6530403H02Rik 4.454301e-16 1.1334537 0.169 0.091 1.336290e-12 CTL_MUT
## Ptpn6 4.520244e-16 0.7170448 0.116 0.004 1.356073e-12 CTL_MUT
## Gbp5 4.793948e-16 -2.9793519 0.103 0.003 1.438184e-12 CTL_MUT
## Ctsd 5.175886e-16 4.7242648 0.221 0.243 1.552766e-12 CTL_MUT
## Aldoc 5.597712e-16 -6.3492138 0.399 0.425 1.679314e-12 CTL_MUT
## Phlda1 5.741140e-16 1.0353320 0.154 0.058 1.722342e-12 CTL_MUT
## Clstn2 7.679259e-16 -0.3763680 0.372 0.372 2.303778e-12 CTL_MUT
## Cenpp 7.684689e-16 5.4937353 0.195 0.040 2.305407e-12 CTL_MUT
## Tprn 7.935209e-16 2.3925499 0.154 0.027 2.380563e-12 CTL_MUT
## Slc25a34 9.193884e-16 -0.8800221 0.169 0.008 2.758165e-12 CTL_MUT
## S100b 9.236631e-16 7.3082757 0.226 0.155 2.770989e-12 CTL_MUT
## Olig2 1.022592e-15 -8.5563725 0.144 0.034 3.067775e-12 CTL_MUT
## Mlip 1.091142e-15 2.4893183 0.246 0.224 3.273426e-12 CTL_MUT
## Hfe 1.133383e-15 -6.9741492 0.127 0.006 3.400149e-12 CTL_MUT
## Cntnap2 1.149953e-15 -3.5837321 0.358 0.329 3.449858e-12 CTL_MUT
## Epha10 1.213035e-15 -0.5504992 0.183 0.131 3.639105e-12 CTL_MUT
## Mcm3 1.794538e-15 -3.4360573 0.175 0.005 5.383614e-12 CTL_MUT
## Galntl6 1.874409e-15 0.7277442 0.237 0.223 5.623226e-12 CTL_MUT
## Adamts18 1.896890e-15 11.7726560 0.136 0.029 5.690670e-12 CTL_MUT
## Slc19a3 2.438959e-15 -4.9906147 0.113 0.008 7.316878e-12 CTL_MUT
## Adamts6 2.464665e-15 -3.4431789 0.189 0.032 7.393996e-12 CTL_MUT
## Mettl11b 2.548177e-15 -9.1675504 0.155 0.009 7.644532e-12 CTL_MUT
## Cks2 2.739909e-15 -4.2789111 0.108 0.012 8.219726e-12 CTL_MUT
## Slc2a1 2.847362e-15 -2.0522523 0.144 0.131 8.542087e-12 CTL_MUT
## Sfta3-ps 3.157994e-15 -0.5246637 0.038 0.112 9.473981e-12 CTL_MUT
## mt-Atp6 3.158224e-15 -0.8098843 0.483 0.458 9.474672e-12 CTL_MUT
## Gm29773 3.428171e-15 -2.7596510 0.195 0.003 1.028451e-11 CTL_MUT
## Gjc1 3.506829e-15 0.3232832 0.115 0.029 1.052049e-11 CTL_MUT
## Rora 4.190280e-15 -3.1545542 0.363 0.354 1.257084e-11 CTL_MUT
## Cntn6 4.428012e-15 -5.7122800 0.220 0.162 1.328404e-11 CTL_MUT
## Unc5d 4.530875e-15 -0.2503195 0.326 0.314 1.359263e-11 CTL_MUT
## Cdk6 5.514689e-15 3.5883939 0.162 0.026 1.654407e-11 CTL_MUT
## Trhr 6.746565e-15 -2.3297838 0.132 0.009 2.023969e-11 CTL_MUT
## Ptprb 7.182882e-15 -4.7630494 0.103 0.072 2.154864e-11 CTL_MUT
## Txnip 7.592116e-15 6.2870782 0.134 0.060 2.277635e-11 CTL_MUT
## Lrrtm4 1.165248e-14 -3.1674718 0.388 0.361 3.495745e-11 CTL_MUT
## Bex3 1.189457e-14 -0.2807450 0.278 0.343 3.568371e-11 CTL_MUT
## Zfhx3 1.215158e-14 -15.1755031 0.154 0.121 3.645474e-11 CTL_MUT
## Dut 1.308497e-14 16.3022246 0.145 0.077 3.925492e-11 CTL_MUT
## Gm49539 1.515062e-14 6.5774314 0.205 0.005 4.545186e-11 CTL_MUT
## 1700007P06Rik 1.646112e-14 2.5393276 0.186 0.004 4.938337e-11 CTL_MUT
## March1 1.996250e-14 -0.3710264 0.391 0.384 5.988751e-11 CTL_MUT
## Gm49678 2.075480e-14 -2.6930253 0.238 0.175 6.226441e-11 CTL_MUT
## Nme2 2.079550e-14 -10.9101966 0.361 0.373 6.238650e-11 CTL_MUT
## Hspa12b 2.339115e-14 -2.3502207 0.112 0.017 7.017345e-11 CTL_MUT
## Sorcs3 2.341541e-14 -4.5963225 0.294 0.274 7.024622e-11 CTL_MUT
## Gm973 2.921314e-14 -10.4773979 0.150 0.021 8.763943e-11 CTL_MUT
## Pld1 3.079105e-14 -1.4847180 0.151 0.049 9.237316e-11 CTL_MUT
## 1700016K05Rik 3.194792e-14 -2.7423970 0.159 0.005 9.584375e-11 CTL_MUT
## Gad1 3.241244e-14 -5.1935715 0.152 0.116 9.723731e-11 CTL_MUT
## Ppfibp2 3.378604e-14 -5.3138121 0.175 0.033 1.013581e-10 CTL_MUT
## Brinp1 3.412910e-14 -1.1740243 0.389 0.390 1.023873e-10 CTL_MUT
## Sh2d6 3.638051e-14 -6.1206894 0.106 0.002 1.091415e-10 CTL_MUT
## Lgals1 3.954440e-14 -3.9455262 0.160 0.026 1.186332e-10 CTL_MUT
## Pdgfd 3.956034e-14 -7.7391281 0.106 0.040 1.186810e-10 CTL_MUT
## Adcy2 4.520190e-14 -3.0482120 0.365 0.363 1.356057e-10 CTL_MUT
## Fzd4 4.617529e-14 -0.4947943 0.146 0.027 1.385259e-10 CTL_MUT
## Id4 5.953223e-14 -8.3923048 0.186 0.094 1.785967e-10 CTL_MUT
## Gm32916 7.203830e-14 -1.8723605 0.212 0.005 2.161149e-10 CTL_MUT
## Zap70 7.275286e-14 -3.0297015 0.174 0.004 2.182586e-10 CTL_MUT
## Marcks 7.377613e-14 -1.3035280 0.348 0.378 2.213284e-10 CTL_MUT
## Chrna7 8.674431e-14 6.9356617 0.186 0.041 2.602329e-10 CTL_MUT
## 4930567K20Rik 9.778935e-14 2.4180493 0.185 0.017 2.933681e-10 CTL_MUT
## Necab1 1.007311e-13 -1.2052464 0.213 0.230 3.021933e-10 CTL_MUT
## Dusp2 1.040456e-13 0.3361347 0.145 0.004 3.121368e-10 CTL_MUT
## Plaat3 1.323003e-13 -16.3246185 0.165 0.061 3.969010e-10 CTL_MUT
## Gm49953 1.460261e-13 -1.4473676 0.120 0.002 4.380782e-10 CTL_MUT
## Rtl4 1.501694e-13 2.9703593 0.248 0.195 4.505082e-10 CTL_MUT
## Sox6 1.561109e-13 -3.4742615 0.188 0.152 4.683328e-10 CTL_MUT
## Abca8a 1.595943e-13 -3.6985813 0.177 0.006 4.787830e-10 CTL_MUT
## Ccl27a 1.596690e-13 0.7025758 0.231 0.283 4.790069e-10 CTL_MUT
## Cdhr1 2.155148e-13 -1.5196972 0.173 0.003 6.465443e-10 CTL_MUT
## Acot11 2.243757e-13 -2.2356936 0.160 0.037 6.731270e-10 CTL_MUT
## H3f3b 2.283959e-13 1.6982641 0.395 0.416 6.851877e-10 CTL_MUT
## Tmem125 2.392362e-13 -8.5936373 0.144 0.018 7.177087e-10 CTL_MUT
## Pip5k1b 2.396157e-13 -10.3697875 0.176 0.117 7.188472e-10 CTL_MUT
## Sbspon 2.421776e-13 2.4715247 0.182 0.003 7.265327e-10 CTL_MUT
## Gm45323 2.451854e-13 -5.2409980 0.122 0.007 7.355563e-10 CTL_MUT
## Sntg1 2.683469e-13 -0.9295812 0.398 0.387 8.050407e-10 CTL_MUT
## Pdzph1 2.724248e-13 -6.7992269 0.156 0.021 8.172743e-10 CTL_MUT
## Atp5d 2.777215e-13 1.6323026 0.373 0.411 8.331644e-10 CTL_MUT
## Mertk 2.970068e-13 2.3692933 0.205 0.201 8.910203e-10 CTL_MUT
## Gm11627 3.063622e-13 1.7119149 0.186 0.040 9.190865e-10 CTL_MUT
## Pcp4l1 3.184799e-13 -9.9330342 0.148 0.050 9.554398e-10 CTL_MUT
## Sema5a 3.319338e-13 -2.1553947 0.182 0.105 9.958014e-10 CTL_MUT
## Cacnb2 3.464789e-13 -3.3598981 0.336 0.331 1.039437e-09 CTL_MUT
## Cldn11 3.824209e-13 -4.8282248 0.220 0.144 1.147263e-09 CTL_MUT
## Gm15527 3.985774e-13 -2.4512197 0.121 0.002 1.195732e-09 CTL_MUT
## Rpe65 4.060806e-13 1.0184701 0.134 0.003 1.218242e-09 CTL_MUT
## Fam114a1 4.291759e-13 -1.1845640 0.183 0.010 1.287528e-09 CTL_MUT
## Bcan 4.716350e-13 -6.3340709 0.210 0.196 1.414905e-09 CTL_MUT
## 4930401C15Rik 4.858662e-13 -4.4265424 0.107 0.002 1.457599e-09 CTL_MUT
## Kcnh7 5.039107e-13 -0.7548320 0.431 0.399 1.511732e-09 CTL_MUT
## Pla2g7 6.041722e-13 3.4830508 0.194 0.160 1.812517e-09 CTL_MUT
## C1ql3 6.544604e-13 -1.1659036 0.282 0.349 1.963381e-09 CTL_MUT
## Mog 6.649330e-13 -2.4859190 0.181 0.110 1.994799e-09 CTL_MUT
## Zfp469 7.710162e-13 -10.8257839 0.126 0.003 2.313049e-09 CTL_MUT
## Adgrl3 9.302470e-13 -0.8676588 0.446 0.414 2.790741e-09 CTL_MUT
## Rprml 1.049308e-12 0.9968065 0.211 0.278 3.147923e-09 CTL_MUT
## Cdh8 1.221394e-12 7.6252094 0.278 0.301 3.664181e-09 CTL_MUT
## Rhob 1.396650e-12 -3.2477893 0.296 0.274 4.189951e-09 CTL_MUT
## Tspan18 1.433170e-12 -3.0740385 0.146 0.004 4.299510e-09 CTL_MUT
## Rnf7 1.455306e-12 1.5278281 0.242 0.215 4.365918e-09 CTL_MUT
## Gm20125 1.456910e-12 -8.2988444 0.125 0.018 4.370730e-09 CTL_MUT
## Cntn5 1.550223e-12 -2.6991289 0.347 0.334 4.650668e-09 CTL_MUT
## Anln 1.859995e-12 -2.2941692 0.125 0.032 5.579985e-09 CTL_MUT
## Rab3c 2.239904e-12 -5.0233530 0.304 0.331 6.719711e-09 CTL_MUT
## Lrg1 2.303574e-12 -2.6707391 0.136 0.003 6.910723e-09 CTL_MUT
## Cacna1f 2.328597e-12 0.3907973 0.138 0.003 6.985791e-09 CTL_MUT
## Ccdc183 2.575760e-12 -1.0489225 0.162 0.003 7.727281e-09 CTL_MUT
## Gm15738 2.617724e-12 -3.5015223 0.224 0.154 7.853172e-09 CTL_MUT
## Oprk1 2.682920e-12 -4.9367572 0.105 0.037 8.048761e-09 CTL_MUT
## Slco1c1 3.068961e-12 0.2522404 0.164 0.129 9.206884e-09 CTL_MUT
## Ptn 3.476025e-12 16.6433621 0.396 0.387 1.042807e-08 CTL_MUT
## Comp 3.964291e-12 -2.5262040 0.112 0.002 1.189287e-08 CTL_MUT
## 2900052N01Rik 4.317877e-12 2.4459977 0.202 0.053 1.295363e-08 CTL_MUT
## Abi3 4.627577e-12 2.2134266 0.100 0.011 1.388273e-08 CTL_MUT
## Itga9 4.804447e-12 -10.5423452 0.142 0.024 1.441334e-08 CTL_MUT
## Rgs7 5.033575e-12 -0.4628138 0.410 0.409 1.510073e-08 CTL_MUT
## Ifitm2 5.138618e-12 8.1921477 0.156 0.038 1.541585e-08 CTL_MUT
## Trabd2b 5.220223e-12 -3.6023244 0.151 0.046 1.566067e-08 CTL_MUT
## B230323A14Rik 5.506695e-12 -1.5953347 0.189 0.003 1.652009e-08 CTL_MUT
## Gm33206 5.640488e-12 -3.9757846 0.194 0.008 1.692147e-08 CTL_MUT
## Itga8 5.709151e-12 -2.7539961 0.173 0.091 1.712745e-08 CTL_MUT
## Serpinf1 5.831193e-12 -4.3917591 0.154 0.008 1.749358e-08 CTL_MUT
## Chgb 6.143373e-12 3.3224024 0.320 0.392 1.843012e-08 CTL_MUT
## Rhoj 7.024743e-12 -3.0210762 0.164 0.025 2.107423e-08 CTL_MUT
## St8sia6 7.483881e-12 -2.7363553 0.163 0.006 2.245164e-08 CTL_MUT
## Col24a1 7.831984e-12 -2.4601823 0.155 0.013 2.349595e-08 CTL_MUT
## St3gal6 8.608528e-12 -5.3204006 0.146 0.078 2.582559e-08 CTL_MUT
## Mlph 8.622932e-12 -2.2226996 0.125 0.006 2.586880e-08 CTL_MUT
## Spock3 8.994459e-12 10.5657623 0.236 0.211 2.698338e-08 CTL_MUT
## Itgb2 1.043984e-11 -3.3872896 0.129 0.006 3.131953e-08 CTL_MUT
## Slc16a12 1.056926e-11 -3.6285884 0.153 0.013 3.170779e-08 CTL_MUT
## Kcnc2 1.107286e-11 -1.3266970 0.257 0.230 3.321859e-08 CTL_MUT
## Tbxas1 1.175003e-11 1.9527585 0.124 0.016 3.525009e-08 CTL_MUT
## Dbx2 1.243986e-11 4.9389831 0.197 0.034 3.731957e-08 CTL_MUT
## Fabp5 1.454325e-11 -20.1977124 0.408 0.427 4.362975e-08 CTL_MUT
## Nuak2 1.580963e-11 6.0872496 0.109 0.004 4.742888e-08 CTL_MUT
## Bcam 1.592887e-11 -5.4425092 0.181 0.009 4.778661e-08 CTL_MUT
## Setdb2 1.612383e-11 5.5789741 0.224 0.013 4.837150e-08 CTL_MUT
## Glis3 1.745862e-11 7.3532685 0.127 0.058 5.237587e-08 CTL_MUT
## Myl12a 1.802917e-11 8.0211916 0.157 0.053 5.408752e-08 CTL_MUT
## Gm17638 1.826278e-11 1.0909711 0.145 0.003 5.478834e-08 CTL_MUT
## Aox1 1.872950e-11 -12.8176925 0.140 0.012 5.618850e-08 CTL_MUT
## Gm33948 2.142371e-11 -2.0197964 0.146 0.004 6.427114e-08 CTL_MUT
## Edn3 2.157832e-11 -1.6594256 0.110 0.007 6.473496e-08 CTL_MUT
## Ifitm3 2.331541e-11 -1.2039529 0.113 0.050 6.994622e-08 CTL_MUT
## Rap2a 2.666127e-11 -0.3878336 0.202 0.195 7.998381e-08 CTL_MUT
## Cmtm3 2.771147e-11 -2.9294774 0.206 0.017 8.313440e-08 CTL_MUT
## D030055H07Rik 2.803918e-11 2.0970365 0.110 0.003 8.411754e-08 CTL_MUT
## Cmklr1 3.017254e-11 0.3882645 0.147 0.004 9.051762e-08 CTL_MUT
## Apod 3.152302e-11 -1.4304654 0.213 0.122 9.456905e-08 CTL_MUT
## Prima1 3.313570e-11 -9.4004053 0.115 0.011 9.940710e-08 CTL_MUT
## Lamp5 4.594700e-11 -0.8357071 0.162 0.142 1.378410e-07 CTL_MUT
## Glud1 4.621630e-11 1.0779111 0.278 0.244 1.386489e-07 CTL_MUT
## Epha3 4.763033e-11 -1.5165942 0.185 0.120 1.428910e-07 CTL_MUT
## Aif1 4.936690e-11 4.2737028 0.159 0.031 1.481007e-07 CTL_MUT
## Cyp2j8 5.291833e-11 -2.1629359 0.125 0.005 1.587550e-07 CTL_MUT
## Htr4 5.568706e-11 -0.6041399 0.133 0.025 1.670612e-07 CTL_MUT
## Cdca7l 6.251036e-11 0.2711410 0.152 0.004 1.875311e-07 CTL_MUT
## Gm6209 6.686206e-11 -4.5183359 0.142 0.005 2.005862e-07 CTL_MUT
## Stxbp6 6.982304e-11 -6.0090742 0.242 0.179 2.094691e-07 CTL_MUT
## Nwd2 7.100729e-11 -0.5531684 0.253 0.239 2.130219e-07 CTL_MUT
## Atp13a4 8.217112e-11 -0.3852097 0.133 0.022 2.465134e-07 CTL_MUT
## Paqr5 9.349005e-11 -3.2544745 0.101 0.026 2.804702e-07 CTL_MUT
## H2afj 9.854944e-11 1.3236578 0.351 0.372 2.956483e-07 CTL_MUT
## Gm32828 1.059768e-10 -2.9172826 0.159 0.017 3.179305e-07 CTL_MUT
## Meltf 1.247003e-10 1.9152882 0.151 0.002 3.741008e-07 CTL_MUT
## Gm12404 1.302345e-10 2.9799920 0.195 0.003 3.907034e-07 CTL_MUT
## Prdx1 1.303146e-10 0.3109186 0.387 0.383 3.909437e-07 CTL_MUT
## Tm6sf2 1.543783e-10 -0.7814087 0.187 0.003 4.631348e-07 CTL_MUT
## Gm41492 1.557656e-10 1.3212935 0.109 0.003 4.672967e-07 CTL_MUT
## Tspan2 1.752653e-10 -5.0899747 0.211 0.141 5.257958e-07 CTL_MUT
## Ccl6 1.928495e-10 -2.2485814 0.172 0.006 5.785484e-07 CTL_MUT
## Cd164 2.101859e-10 -2.4768368 0.165 0.085 6.305576e-07 CTL_MUT
## Trim59 2.422658e-10 -1.0937063 0.142 0.028 7.267975e-07 CTL_MUT
## Car14 2.504314e-10 -5.2960784 0.139 0.022 7.512942e-07 CTL_MUT
## Prkd1 2.685479e-10 -0.9056817 0.205 0.157 8.056436e-07 CTL_MUT
## Prkg1 2.821993e-10 -0.9801404 0.385 0.381 8.465978e-07 CTL_MUT
## Nrg1 3.282906e-10 -7.6719666 0.403 0.373 9.848718e-07 CTL_MUT
## Dio2 3.416226e-10 -1.8572338 0.157 0.088 1.024868e-06 CTL_MUT
## Dlx1 3.598923e-10 -3.1028005 0.136 0.025 1.079677e-06 CTL_MUT
## Gngt2 3.959513e-10 -4.8668558 0.175 0.010 1.187854e-06 CTL_MUT
## Bex1 4.112300e-10 3.2929324 0.169 0.200 1.233690e-06 CTL_MUT
## Stra6 4.378305e-10 -6.8024382 0.128 0.006 1.313491e-06 CTL_MUT
## Wnt5a 4.561237e-10 -1.1343623 0.153 0.020 1.368371e-06 CTL_MUT
## Gm36988 5.241828e-10 0.7685377 0.168 0.016 1.572548e-06 CTL_MUT
## Ctla2b 5.914174e-10 -1.0746506 0.130 0.010 1.774252e-06 CTL_MUT
## Ermn 5.924670e-10 -5.3255869 0.169 0.089 1.777401e-06 CTL_MUT
## P2ry1 6.320846e-10 -3.9049901 0.150 0.004 1.896254e-06 CTL_MUT
## Notch4 6.384678e-10 -12.8072009 0.189 0.011 1.915403e-06 CTL_MUT
## Abca1 6.607441e-10 5.2050565 0.185 0.093 1.982232e-06 CTL_MUT
## Clic4 7.467022e-10 -2.8749202 0.203 0.125 2.240106e-06 CTL_MUT
## Ecscr 8.088714e-10 -2.0472400 0.140 0.012 2.426614e-06 CTL_MUT
## Col6a1 8.167327e-10 0.2569358 0.156 0.042 2.450198e-06 CTL_MUT
## Adam12 9.208387e-10 -4.2367309 0.130 0.025 2.762516e-06 CTL_MUT
## Syn3 9.212601e-10 -2.7066306 0.291 0.259 2.763780e-06 CTL_MUT
## Stab1 9.586037e-10 -0.6448042 0.114 0.020 2.875811e-06 CTL_MUT
## Rprm 9.936145e-10 5.9709944 0.118 0.088 2.980843e-06 CTL_MUT
## Bvht 1.164394e-09 -0.8562632 0.145 0.008 3.493183e-06 CTL_MUT
## Gm20642 1.190960e-09 -2.1500551 0.311 0.323 3.572879e-06 CTL_MUT
## Rab3b 1.230299e-09 5.4636895 0.142 0.063 3.690897e-06 CTL_MUT
## Ndn 1.444564e-09 0.4437149 0.157 0.166 4.333693e-06 CTL_MUT
## B2m 1.450800e-09 2.0244223 0.171 0.125 4.352399e-06 CTL_MUT
## Rps9 1.663274e-09 -5.6827786 0.404 0.420 4.989821e-06 CTL_MUT
## Gm27239 1.690204e-09 -2.0157094 0.196 0.005 5.070612e-06 CTL_MUT
## Gpc5 1.746860e-09 -1.5449518 0.241 0.248 5.240581e-06 CTL_MUT
## Map3k1 1.967439e-09 -14.7219122 0.177 0.027 5.902318e-06 CTL_MUT
## Hmgcs2 2.011640e-09 -4.6094848 0.159 0.013 6.034921e-06 CTL_MUT
## Slc39a12 2.039092e-09 -0.4956246 0.144 0.083 6.117277e-06 CTL_MUT
## Rhoc 2.041456e-09 -1.7750607 0.152 0.034 6.124368e-06 CTL_MUT
## Hbb-bs 2.089050e-09 -1.6965275 0.142 0.003 6.267149e-06 CTL_MUT
## Gng5 2.369536e-09 -6.8024506 0.310 0.275 7.108609e-06 CTL_MUT
## Cd80 2.370086e-09 5.4816379 0.143 0.003 7.110259e-06 CTL_MUT
## Calb1 2.550563e-09 -6.0907423 0.148 0.151 7.651688e-06 CTL_MUT
## Rgs10 2.762992e-09 -5.7044912 0.141 0.093 8.288977e-06 CTL_MUT
## Gm17750 2.938154e-09 -4.7788445 0.159 0.052 8.814463e-06 CTL_MUT
## Rnf122 2.939555e-09 -1.8468335 0.162 0.014 8.818665e-06 CTL_MUT
## Inava 3.084537e-09 -3.1301570 0.163 0.007 9.253611e-06 CTL_MUT
## Iqgap2 3.123274e-09 2.1487340 0.193 0.127 9.369822e-06 CTL_MUT
## Chrm3 3.532394e-09 2.1889551 0.357 0.357 1.059718e-05 CTL_MUT
## Sorbs2 3.965830e-09 2.3647066 0.410 0.406 1.189749e-05 CTL_MUT
## Heg1 4.205905e-09 3.4065921 0.154 0.075 1.261772e-05 CTL_MUT
## 2700046A07Rik 4.258309e-09 -2.5074736 0.132 0.010 1.277493e-05 CTL_MUT
## Ralyl 4.370169e-09 -0.7138734 0.404 0.384 1.311051e-05 CTL_MUT
## H2afz 4.521166e-09 -3.2660621 0.363 0.397 1.356350e-05 CTL_MUT
## Crygn 4.787960e-09 1.0442379 0.117 0.003 1.436388e-05 CTL_MUT
## Slc6a11 5.092416e-09 10.9529403 0.182 0.114 1.527725e-05 CTL_MUT
## Hpgd 5.272410e-09 -2.9988170 0.115 0.037 1.581723e-05 CTL_MUT
## Lypd1 5.350405e-09 -5.5448655 0.129 0.075 1.605122e-05 CTL_MUT
## Cntn4 6.205547e-09 -12.0025934 0.380 0.365 1.861664e-05 CTL_MUT
## Slit3 6.435343e-09 -1.3076844 0.340 0.340 1.930603e-05 CTL_MUT
## 4930425L21Rik 6.546334e-09 2.7689669 0.175 0.003 1.963900e-05 CTL_MUT
## Tagln 7.145356e-09 -0.3197069 0.101 0.007 2.143607e-05 CTL_MUT
## Greb1l 7.223930e-09 0.4647477 0.165 0.103 2.167179e-05 CTL_MUT
## Gpr149 7.347399e-09 -3.0447271 0.121 0.003 2.204220e-05 CTL_MUT
## Pear1 7.426524e-09 -0.8091771 0.124 0.005 2.227957e-05 CTL_MUT
## Adgrv1 8.046754e-09 -1.8605692 0.199 0.019 2.414026e-05 CTL_MUT
## Fxyd6 9.604355e-09 -2.0297909 0.197 0.218 2.881307e-05 CTL_MUT
## Tubb5 9.726864e-09 0.9834608 0.307 0.358 2.918059e-05 CTL_MUT
## Gng11 1.085978e-08 -6.0658123 0.130 0.064 3.257934e-05 CTL_MUT
## Pitpnm2os2 1.193548e-08 -3.0118022 0.143 0.003 3.580644e-05 CTL_MUT
## Gjc2 1.242406e-08 -7.9672813 0.116 0.019 3.727219e-05 CTL_MUT
## Sdk2 1.312253e-08 -3.3428516 0.224 0.143 3.936759e-05 CTL_MUT
## E330020D12Rik 1.357594e-08 -1.9936453 0.161 0.012 4.072781e-05 CTL_MUT
## Pbx3 1.391926e-08 -3.4190824 0.144 0.068 4.175778e-05 CTL_MUT
## Ccnb1ip1 1.477270e-08 4.3095351 0.120 0.003 4.431811e-05 CTL_MUT
## Pde1a 1.555736e-08 -0.8540669 0.395 0.398 4.667207e-05 CTL_MUT
## Notch3 1.570853e-08 1.3341707 0.153 0.017 4.712559e-05 CTL_MUT
## Gabrb1 1.631955e-08 0.2870389 0.419 0.407 4.895866e-05 CTL_MUT
## Clca3a1 1.797339e-08 -0.4280550 0.159 0.005 5.392016e-05 CTL_MUT
## Phactr1 1.807399e-08 -0.4425145 0.447 0.421 5.422197e-05 CTL_MUT
## Tifab 1.930058e-08 0.7985451 0.140 0.003 5.790175e-05 CTL_MUT
## Asic2 1.954524e-08 -8.3373819 0.419 0.394 5.863572e-05 CTL_MUT
## Fcgrt 2.133976e-08 0.8605965 0.148 0.034 6.401929e-05 CTL_MUT
## Prex2 2.625603e-08 1.3664209 0.227 0.212 7.876808e-05 CTL_MUT
## Zwint 2.640227e-08 -0.4169211 0.349 0.393 7.920681e-05 CTL_MUT
## Fkbp5 2.651940e-08 -6.2643323 0.258 0.212 7.955819e-05 CTL_MUT
## Hcrtr2 3.142431e-08 2.7570271 0.160 0.021 9.427292e-05 CTL_MUT
## Gpc6 3.508254e-08 4.8893720 0.343 0.356 1.052476e-04 CTL_MUT
## Tgfb1 3.637578e-08 0.8408144 0.126 0.015 1.091273e-04 CTL_MUT
## Rnf152 4.028582e-08 -9.0525189 0.147 0.043 1.208575e-04 CTL_MUT
## Grm7 4.265841e-08 -4.6452391 0.425 0.402 1.279752e-04 CTL_MUT
## Hs3st2 4.354312e-08 6.9294358 0.212 0.156 1.306294e-04 CTL_MUT
## Moxd1 4.361433e-08 -4.1903652 0.109 0.010 1.308430e-04 CTL_MUT
## Col4a1 4.743366e-08 -2.3059961 0.163 0.102 1.423010e-04 CTL_MUT
## Eva1b 4.919454e-08 -6.0239187 0.129 0.016 1.475836e-04 CTL_MUT
## Slc26a7 5.185538e-08 -2.6050578 0.109 0.003 1.555661e-04 CTL_MUT
## Usp29 5.284730e-08 -10.0124089 0.215 0.178 1.585419e-04 CTL_MUT
## Rasgrp3 5.311873e-08 0.5548570 0.116 0.045 1.593562e-04 CTL_MUT
## Myl6 6.060306e-08 -1.1838910 0.377 0.423 1.818092e-04 CTL_MUT
## Myl1 7.238492e-08 -5.1956247 0.187 0.004 2.171548e-04 CTL_MUT
## Enho 7.320859e-08 -0.7020201 0.179 0.158 2.196258e-04 CTL_MUT
## Cyp27a1 7.991973e-08 -8.0048546 0.160 0.007 2.397592e-04 CTL_MUT
## Ubl3 8.197849e-08 3.3412134 0.270 0.254 2.459355e-04 CTL_MUT
## Il10ra 8.440636e-08 1.6421734 0.100 0.010 2.532191e-04 CTL_MUT
## Cd248 9.183992e-08 -6.5128493 0.130 0.005 2.755198e-04 CTL_MUT
## 4930523C07Rik 9.349046e-08 -2.0803837 0.132 0.009 2.804714e-04 CTL_MUT
## Gm5 9.576881e-08 -1.9133318 0.113 0.004 2.873064e-04 CTL_MUT
## Nat8f5 9.637889e-08 1.4147762 0.131 0.003 2.891367e-04 CTL_MUT
## Megf10 9.883473e-08 -6.4934417 0.160 0.045 2.965042e-04 CTL_MUT
## Spi1 9.929261e-08 -8.3433498 0.115 0.015 2.978778e-04 CTL_MUT
## Ptchd4 1.004404e-07 6.6892952 0.199 0.135 3.013213e-04 CTL_MUT
## Cfap299 1.115828e-07 -5.1987226 0.165 0.030 3.347483e-04 CTL_MUT
## Robo3 1.279287e-07 -9.1526788 0.162 0.045 3.837861e-04 CTL_MUT
## 4930488L21Rik 1.322716e-07 4.0752098 0.168 0.047 3.968148e-04 CTL_MUT
## Ctf1 1.352716e-07 4.1663070 0.154 0.003 4.058148e-04 CTL_MUT
## Bcas1 1.847473e-07 -3.5589243 0.200 0.117 5.542420e-04 CTL_MUT
## Serpinb1a 1.883910e-07 -1.2017582 0.100 0.009 5.651729e-04 CTL_MUT
## Cpne7 1.886239e-07 15.1125295 0.162 0.056 5.658718e-04 CTL_MUT
## Kntc1 1.941889e-07 -0.5070731 0.120 0.005 5.825667e-04 CTL_MUT
## Gm32568 2.006805e-07 -2.3608496 0.106 0.002 6.020416e-04 CTL_MUT
## Sat1 2.048187e-07 0.7016189 0.181 0.106 6.144560e-04 CTL_MUT
## Cpne4 2.049834e-07 -16.1308003 0.224 0.190 6.149502e-04 CTL_MUT
## Adra1a 2.191215e-07 -4.7629872 0.182 0.096 6.573645e-04 CTL_MUT
## Fgd6 2.385810e-07 8.8243712 0.165 0.036 7.157431e-04 CTL_MUT
## Gm9573 2.583608e-07 -1.0846392 0.113 0.002 7.750823e-04 CTL_MUT
## Slc5a7 2.636927e-07 -0.9400622 0.104 0.003 7.910781e-04 CTL_MUT
## Evi2a 2.640824e-07 -5.6767780 0.157 0.034 7.922472e-04 CTL_MUT
## Gpr4 2.699656e-07 0.6604288 0.111 0.009 8.098969e-04 CTL_MUT
## Adgre5 3.067072e-07 -13.0727546 0.164 0.011 9.201216e-04 CTL_MUT
## Ptafr 3.232110e-07 -2.5702521 0.130 0.006 9.696330e-04 CTL_MUT
## Vwc2l 3.358980e-07 -3.5469093 0.113 0.062 1.007694e-03 CTL_MUT
## Plcxd3 3.451972e-07 -8.3854873 0.179 0.088 1.035592e-03 CTL_MUT
## Tas1r1 3.452152e-07 -0.5842359 0.134 0.002 1.035646e-03 CTL_MUT
## Lrrc4c 3.506097e-07 0.5220156 0.390 0.381 1.051829e-03 CTL_MUT
## Qrfpr 3.562051e-07 0.9257184 0.185 0.008 1.068615e-03 CTL_MUT
## Cox4i2 4.025771e-07 -5.7206355 0.129 0.009 1.207731e-03 CTL_MUT
## 9630002D21Rik 4.271909e-07 -4.1711931 0.133 0.025 1.281573e-03 CTL_MUT
## Prdx6 4.390882e-07 -0.7068440 0.274 0.241 1.317264e-03 CTL_MUT
## Ntng1 4.473802e-07 8.2457496 0.174 0.098 1.342141e-03 CTL_MUT
## Cenpa 5.249169e-07 0.6039577 0.139 0.014 1.574751e-03 CTL_MUT
## Itm2a 5.523400e-07 -3.7729489 0.104 0.083 1.657020e-03 CTL_MUT
## Gm9934 6.145572e-07 -2.0929792 0.104 0.002 1.843672e-03 CTL_MUT
## Gm4756 6.832754e-07 -0.3925690 0.137 0.002 2.049826e-03 CTL_MUT
## Ak9 7.108245e-07 -1.4073707 0.128 0.004 2.132474e-03 CTL_MUT
## Slc16a9 7.216877e-07 -2.5494126 0.143 0.005 2.165063e-03 CTL_MUT
## Afap1l2 8.380280e-07 -5.6750352 0.114 0.019 2.514084e-03 CTL_MUT
## Lhfpl3 9.046561e-07 -2.3537795 0.245 0.194 2.713968e-03 CTL_MUT
## Pdlim2 9.636057e-07 -10.4793033 0.191 0.097 2.890817e-03 CTL_MUT
## Gm26671 1.002136e-06 -2.0247107 0.123 0.006 3.006409e-03 CTL_MUT
## Acan 1.004474e-06 -1.3824508 0.115 0.005 3.013422e-03 CTL_MUT
## Gpnmb 1.017358e-06 -1.0816169 0.116 0.002 3.052074e-03 CTL_MUT
## Flvcr2 1.027919e-06 -1.8696188 0.130 0.006 3.083757e-03 CTL_MUT
## Hexb 1.055985e-06 -7.7856248 0.124 0.125 3.167954e-03 CTL_MUT
## B230311B06Rik 1.075732e-06 -2.9629817 0.210 0.005 3.227197e-03 CTL_MUT
## Mir670hg 1.117827e-06 -8.5675890 0.152 0.066 3.353481e-03 CTL_MUT
## Itgad 1.155770e-06 -10.2208674 0.141 0.024 3.467310e-03 CTL_MUT
## Ccl19 1.187404e-06 1.0220665 0.132 0.002 3.562212e-03 CTL_MUT
## Gm3764 1.209696e-06 -0.3158080 0.246 0.248 3.629087e-03 CTL_MUT
## Slc25a21 1.301046e-06 -1.0644398 0.127 0.007 3.903137e-03 CTL_MUT
## Tbx3 1.337096e-06 1.1389137 0.126 0.008 4.011287e-03 CTL_MUT
## Nkx6-2 1.370784e-06 -1.4792366 0.128 0.040 4.112351e-03 CTL_MUT
## Oprm1 1.545088e-06 -2.5427609 0.187 0.075 4.635264e-03 CTL_MUT
## Meg3 1.575849e-06 0.5073665 0.481 0.445 4.727547e-03 CTL_MUT
## Efhd2 1.720850e-06 -2.6825725 0.249 0.273 5.162550e-03 CTL_MUT
## Nrp1 2.075286e-06 -3.8168605 0.189 0.120 6.225858e-03 CTL_MUT
## Heyl 2.094592e-06 4.3482189 0.123 0.003 6.283775e-03 CTL_MUT
## Cacna2d1 2.111308e-06 0.7786331 0.416 0.414 6.333923e-03 CTL_MUT
## Frem1 2.203352e-06 -2.0494950 0.133 0.010 6.610056e-03 CTL_MUT
## Anxa5 2.275184e-06 -18.8099037 0.170 0.062 6.825553e-03 CTL_MUT
## Gas2l3 2.394852e-06 -2.1440445 0.132 0.004 7.184555e-03 CTL_MUT
## Ndrg2 2.901147e-06 1.4706380 0.317 0.346 8.703440e-03 CTL_MUT
## A230001M10Rik 3.053469e-06 -11.3669463 0.114 0.011 9.160407e-03 CTL_MUT
## Coro6 3.201128e-06 -1.2047347 0.146 0.025 9.603384e-03 CTL_MUT
## Tbx15 3.338146e-06 -4.2282402 0.225 0.005 1.001444e-02 CTL_MUT
## Hmgb2 3.466727e-06 1.0000461 0.110 0.079 1.040018e-02 CTL_MUT
## Card10 4.288769e-06 -2.3105509 0.156 0.006 1.286631e-02 CTL_MUT
## Mlf1 4.661007e-06 -2.7587212 0.149 0.004 1.398302e-02 CTL_MUT
## Gm36738 4.838686e-06 -1.6856271 0.105 0.002 1.451606e-02 CTL_MUT
## Ryr2 4.896582e-06 -0.2557961 0.412 0.404 1.468975e-02 CTL_MUT
## Rmst 5.023610e-06 -2.8993120 0.198 0.165 1.507083e-02 CTL_MUT
## Megf6 5.213273e-06 -2.0175632 0.141 0.006 1.563982e-02 CTL_MUT
## Grin2a 5.730076e-06 -0.3151442 0.421 0.400 1.719023e-02 CTL_MUT
## Cd163 5.877300e-06 -3.3240231 0.153 0.005 1.763190e-02 CTL_MUT
## Hspa1a 6.113283e-06 -1.3254220 0.172 0.022 1.833985e-02 CTL_MUT
## Ddx11 6.207094e-06 -2.6438496 0.131 0.003 1.862128e-02 CTL_MUT
## Btbd17 6.287506e-06 -1.3730100 0.167 0.054 1.886252e-02 CTL_MUT
## Plpp4 6.328392e-06 -3.5533375 0.130 0.047 1.898518e-02 CTL_MUT
## Tiam2 6.395884e-06 -1.6626911 0.190 0.149 1.918765e-02 CTL_MUT
## Tmem132c 6.493027e-06 -3.9132111 0.114 0.016 1.947908e-02 CTL_MUT
## Gm42439 6.648434e-06 0.8046347 0.179 0.107 1.994530e-02 CTL_MUT
## Apold1 6.808294e-06 -3.3313912 0.126 0.020 2.042488e-02 CTL_MUT
## Chst3 6.959030e-06 -8.8455495 0.184 0.007 2.087709e-02 CTL_MUT
## Hgf 6.980264e-06 -1.4234270 0.183 0.024 2.094079e-02 CTL_MUT
## Samsn1 7.248753e-06 -7.4676491 0.147 0.013 2.174626e-02 CTL_MUT
## Cited2 7.585204e-06 -2.8616720 0.150 0.086 2.275561e-02 CTL_MUT
## Rgs6 7.900934e-06 -1.0344776 0.359 0.360 2.370280e-02 CTL_MUT
## Gm37459 8.389993e-06 -4.2805401 0.188 0.064 2.516998e-02 CTL_MUT
## Hs6st3 8.495062e-06 -2.3398615 0.303 0.295 2.548519e-02 CTL_MUT
## Gm20463 8.625073e-06 -3.9373750 0.125 0.002 2.587522e-02 CTL_MUT
## Lrrc9 8.787220e-06 -5.0688228 0.161 0.009 2.636166e-02 CTL_MUT
## Nrn1 9.068700e-06 -1.2343417 0.264 0.334 2.720610e-02 CTL_MUT
## 4930420G21Rik 1.043961e-05 -2.3014905 0.103 0.017 3.131882e-02 CTL_MUT
## Serping1 1.094617e-05 -2.7119723 0.120 0.005 3.283852e-02 CTL_MUT
## Pxmp2 1.094728e-05 3.1734093 0.198 0.017 3.284184e-02 CTL_MUT
## Cdkn3 1.104026e-05 -8.0260674 0.146 0.004 3.312077e-02 CTL_MUT
## Rbp4 1.143286e-05 1.4932389 0.114 0.045 3.429859e-02 CTL_MUT
## Gm29571 1.216491e-05 -1.8185775 0.130 0.004 3.649472e-02 CTL_MUT
## Slco1a4 1.235293e-05 -3.5104709 0.106 0.086 3.705880e-02 CTL_MUT
## Gm47027 1.370728e-05 -5.2038810 0.131 0.008 4.112184e-02 CTL_MUT
## Frmpd4 1.594782e-05 -2.3426622 0.376 0.372 4.784347e-02 CTL_MUT
## Mt1 1.657950e-05 -3.2119660 0.355 0.355 4.973850e-02 CTL_MUT
## Ccdc141 1.831130e-05 -3.8678089 0.128 0.085 5.493389e-02 CTL_MUT
## Runx2 1.890905e-05 -2.4778348 0.235 0.147 5.672716e-02 CTL_MUT
## Gria3 1.952557e-05 -0.3288427 0.411 0.409 5.857671e-02 CTL_MUT
## Hist1h2bc 1.954552e-05 0.6691490 0.261 0.191 5.863656e-02 CTL_MUT
## Gad2 2.121384e-05 -0.4755963 0.166 0.141 6.364152e-02 CTL_MUT
## Plekhh1 2.132864e-05 -0.5460347 0.141 0.038 6.398593e-02 CTL_MUT
## Fbxo47 2.153922e-05 -4.9216433 0.116 0.004 6.461765e-02 CTL_MUT
## Rcsd1 2.318778e-05 -5.8581852 0.123 0.013 6.956334e-02 CTL_MUT
## Crispld2 2.635070e-05 -2.8069434 0.170 0.006 7.905210e-02 CTL_MUT
## Mlxipl 2.998624e-05 -2.8841247 0.155 0.007 8.995873e-02 CTL_MUT
## Adm 3.158858e-05 -2.6049965 0.131 0.004 9.476574e-02 CTL_MUT
## Sema5b 3.563727e-05 1.5497311 0.154 0.042 1.069118e-01 CTL_MUT
## Gm15261 3.768206e-05 -2.4608321 0.175 0.006 1.130462e-01 CTL_MUT
## Fcgr1 3.785806e-05 -2.1405225 0.103 0.005 1.135742e-01 CTL_MUT
## Rbp1 3.826467e-05 -6.1609804 0.160 0.046 1.147940e-01 CTL_MUT
## Erc2 3.843768e-05 -1.0284986 0.405 0.386 1.153130e-01 CTL_MUT
## Ppp1r14a 3.913590e-05 -4.3353139 0.180 0.095 1.174077e-01 CTL_MUT
## 4930473D10Rik 4.273372e-05 -1.1185996 0.192 0.018 1.282012e-01 CTL_MUT
## Serpine2 4.432722e-05 -1.0758165 0.238 0.193 1.329817e-01 CTL_MUT
## Casp8 4.529304e-05 2.8493939 0.144 0.010 1.358791e-01 CTL_MUT
## Hhex 5.160677e-05 5.0200641 0.104 0.004 1.548203e-01 CTL_MUT
## Pgm5 5.474380e-05 -2.5427857 0.132 0.004 1.642314e-01 CTL_MUT
## Pde1c 5.546719e-05 3.7985888 0.201 0.034 1.664016e-01 CTL_MUT
## Fam83d 5.597507e-05 -8.5754004 0.142 0.011 1.679252e-01 CTL_MUT
## Cntnap5a 5.614576e-05 7.4930639 0.280 0.237 1.684373e-01 CTL_MUT
## Rarb 5.734284e-05 -4.0530324 0.195 0.026 1.720285e-01 CTL_MUT
## Loxl1 5.875414e-05 -1.4162022 0.124 0.002 1.762624e-01 CTL_MUT
## Nxph3 5.913417e-05 -4.5056370 0.157 0.045 1.774025e-01 CTL_MUT
## Tmem63a 6.236923e-05 -9.1545998 0.141 0.024 1.871077e-01 CTL_MUT
## Cldn14 6.303296e-05 -4.0371911 0.109 0.020 1.890989e-01 CTL_MUT
## Fam20a 6.697988e-05 -11.8341299 0.134 0.046 2.009396e-01 CTL_MUT
## Cdca7 7.454738e-05 -9.9570869 0.117 0.014 2.236422e-01 CTL_MUT
## Marcksl1 7.485759e-05 4.2286755 0.176 0.165 2.245728e-01 CTL_MUT
## Notum 7.528834e-05 -5.6686434 0.152 0.005 2.258650e-01 CTL_MUT
## Plxnb3 7.874049e-05 -8.3523653 0.138 0.018 2.362215e-01 CTL_MUT
## Klk8 7.882616e-05 -0.8761422 0.153 0.005 2.364785e-01 CTL_MUT
## Grrp1 8.076794e-05 2.5181925 0.135 0.009 2.423038e-01 CTL_MUT
## Tafa1 8.796464e-05 -0.8520617 0.286 0.282 2.638939e-01 CTL_MUT
## Nptx1 9.203265e-05 0.9916621 0.218 0.218 2.760980e-01 CTL_MUT
## Alcam 9.377870e-05 -1.2135102 0.354 0.371 2.813361e-01 CTL_MUT
## Robo1 9.903852e-05 1.8039551 0.344 0.342 2.971155e-01 CTL_MUT
## Gm38505 1.051253e-04 -1.2615340 0.126 0.052 3.153760e-01 CTL_MUT
## Rgcc 1.086935e-04 -4.6312927 0.189 0.138 3.260806e-01 CTL_MUT
## Airn 1.102379e-04 -6.0611624 0.181 0.048 3.307136e-01 CTL_MUT
## Ntng2 1.117403e-04 -7.3368904 0.161 0.034 3.352209e-01 CTL_MUT
## Ifi27l2a 1.178999e-04 -1.7891173 0.127 0.003 3.536996e-01 CTL_MUT
## Lgr5 1.201813e-04 0.8529655 0.184 0.004 3.605438e-01 CTL_MUT
## Selenoh 1.222537e-04 -1.4782153 0.141 0.109 3.667610e-01 CTL_MUT
## Zfp462 1.235352e-04 1.1925809 0.235 0.199 3.706057e-01 CTL_MUT
## Mageb18 1.298375e-04 -0.3345271 0.106 0.007 3.895124e-01 CTL_MUT
## Gm13052 1.316809e-04 -1.4433634 0.141 0.048 3.950428e-01 CTL_MUT
## Zfp69 1.334475e-04 1.3402388 0.122 0.003 4.003426e-01 CTL_MUT
## Anp32b 1.368232e-04 -1.9305660 0.177 0.132 4.104695e-01 CTL_MUT
## Fst 1.422104e-04 -1.2491040 0.155 0.012 4.266313e-01 CTL_MUT
## Rflnb 1.471742e-04 -6.8836351 0.119 0.025 4.415225e-01 CTL_MUT
## Cp 1.575115e-04 -3.6611912 0.110 0.034 4.725344e-01 CTL_MUT
## Gm45029 1.694665e-04 -0.8733014 0.106 0.002 5.083995e-01 CTL_MUT
## Cep128 1.696760e-04 -7.1743662 0.198 0.043 5.090281e-01 CTL_MUT
## Dynll2 1.863316e-04 7.8139889 0.305 0.360 5.589949e-01 CTL_MUT
## Dcn 1.943512e-04 -2.6213560 0.137 0.009 5.830536e-01 CTL_MUT
## Atp1a2 1.970827e-04 -3.5037445 0.347 0.357 5.912480e-01 CTL_MUT
## Gm30275 2.164129e-04 -0.7533902 0.126 0.002 6.492386e-01 CTL_MUT
## Exoc3l2 2.187045e-04 -0.9730868 0.120 0.002 6.561135e-01 CTL_MUT
## Dlk1 2.209832e-04 -0.3407263 0.135 0.002 6.629497e-01 CTL_MUT
## Clu 2.477790e-04 -2.3607750 0.386 0.384 7.433369e-01 CTL_MUT
## Tacr1 2.741722e-04 -3.8825446 0.136 0.007 8.225166e-01 CTL_MUT
## Dapp1 2.962917e-04 10.3432497 0.143 0.015 8.888750e-01 CTL_MUT
## Resp18 3.035419e-04 2.8641721 0.138 0.135 9.106258e-01 CTL_MUT
## St6galnac2 3.085537e-04 -0.9660410 0.144 0.006 9.256612e-01 CTL_MUT
## Actg1 3.308823e-04 -0.4872423 0.377 0.431 9.926470e-01 CTL_MUT
## Alk 3.360180e-04 -1.6025371 0.105 0.052 1.000000e+00 CTL_MUT
## A730035I17Rik 3.370390e-04 4.2232146 0.152 0.003 1.000000e+00 CTL_MUT
## Nid2 3.783163e-04 -5.1921597 0.145 0.003 1.000000e+00 CTL_MUT
## Fstl4 3.805826e-04 -4.8265432 0.274 0.250 1.000000e+00 CTL_MUT
## Caln1 3.958435e-04 1.5658533 0.318 0.308 1.000000e+00 CTL_MUT
## Rad51b 4.069988e-04 1.5420866 0.181 0.015 1.000000e+00 CTL_MUT
## Plek 4.091301e-04 -5.8758852 0.119 0.050 1.000000e+00 CTL_MUT
## Ppp1r3g 4.113781e-04 4.6872041 0.180 0.025 1.000000e+00 CTL_MUT
## Olfml3 4.318923e-04 1.4491319 0.107 0.026 1.000000e+00 CTL_MUT
## Mia 4.902893e-04 -1.4398202 0.163 0.006 1.000000e+00 CTL_MUT
## Plk1 5.041319e-04 -0.5470106 0.129 0.004 1.000000e+00 CTL_MUT
## BC006965 5.477494e-04 4.7336800 0.134 0.041 1.000000e+00 CTL_MUT
## Igfbp2 5.733412e-04 -6.2634138 0.157 0.051 1.000000e+00 CTL_MUT
## Gm20083 6.987997e-04 0.7284800 0.126 0.002 1.000000e+00 CTL_MUT
## 4933424G05Rik 7.468719e-04 -3.3027339 0.152 0.059 1.000000e+00 CTL_MUT
## Smim3 7.769832e-04 -6.5807124 0.163 0.042 1.000000e+00 CTL_MUT
## Kcne1l 8.029115e-04 -5.8249001 0.185 0.004 1.000000e+00 CTL_MUT
## Mill2 8.101831e-04 -2.3891730 0.143 0.011 1.000000e+00 CTL_MUT
## Cd274 8.315515e-04 -0.5126176 0.115 0.003 1.000000e+00 CTL_MUT
## Trp53cor1 8.320816e-04 1.2505208 0.195 0.008 1.000000e+00 CTL_MUT
## Hpgds 8.470938e-04 -1.8504574 0.146 0.062 1.000000e+00 CTL_MUT
## Olfr287 8.512938e-04 5.6360605 0.155 0.004 1.000000e+00 CTL_MUT
## Ermap 8.554079e-04 -0.7985341 0.101 0.003 1.000000e+00 CTL_MUT
## Isg15 9.576718e-04 -1.2494919 0.123 0.006 1.000000e+00 CTL_MUT
## Gm15880 9.932447e-04 -4.6204670 0.169 0.003 1.000000e+00 CTL_MUT
## Trpc7 1.011310e-03 11.6347976 0.133 0.013 1.000000e+00 CTL_MUT
## Ndst3 1.023228e-03 0.6526979 0.229 0.164 1.000000e+00 CTL_MUT
## Gstp1 1.115043e-03 -0.7974380 0.174 0.093 1.000000e+00 CTL_MUT
## Enpp1 1.138371e-03 -0.7674029 0.178 0.006 1.000000e+00 CTL_MUT
## Lcorl 1.197334e-03 -2.4288762 0.285 0.232 1.000000e+00 CTL_MUT
## Adamts9 1.213731e-03 -2.2640080 0.138 0.021 1.000000e+00 CTL_MUT
## Il6ra 1.245343e-03 -7.1942417 0.131 0.024 1.000000e+00 CTL_MUT
## Osmr 1.308021e-03 -3.9545861 0.125 0.006 1.000000e+00 CTL_MUT
## Parvg 1.316747e-03 -2.6667228 0.123 0.004 1.000000e+00 CTL_MUT
## B3gnt5 1.354510e-03 -3.3155569 0.124 0.004 1.000000e+00 CTL_MUT
## Rgs4 1.407481e-03 9.6627373 0.193 0.256 1.000000e+00 CTL_MUT
## Gjb2 1.438170e-03 1.1214010 0.117 0.008 1.000000e+00 CTL_MUT
## Thbs4 1.517723e-03 -4.2011069 0.177 0.005 1.000000e+00 CTL_MUT
## Zfp36l2 1.570794e-03 2.9570299 0.156 0.055 1.000000e+00 CTL_MUT
## Mapkapk3 1.631915e-03 -4.2775291 0.142 0.004 1.000000e+00 CTL_MUT
## Krtap28-13 1.641239e-03 -0.7360492 0.104 0.000 1.000000e+00 CTL_MUT
## Aqp4 1.698255e-03 -3.0633428 0.173 0.101 1.000000e+00 CTL_MUT
## Il1rapl2 1.705854e-03 -1.1683313 0.203 0.167 1.000000e+00 CTL_MUT
## Synm 1.989673e-03 -10.1393942 0.138 0.050 1.000000e+00 CTL_MUT
## Bicc1 2.042648e-03 0.3511810 0.166 0.100 1.000000e+00 CTL_MUT
## Ghr 2.124998e-03 -5.9761629 0.179 0.097 1.000000e+00 CTL_MUT
## Gm45025 2.311987e-03 -3.4727860 0.129 0.005 1.000000e+00 CTL_MUT
## Gm46224 2.384130e-03 -3.1513915 0.132 0.003 1.000000e+00 CTL_MUT
## Kif18a 2.416114e-03 -0.3969615 0.175 0.008 1.000000e+00 CTL_MUT
## Unc45b 2.419222e-03 -6.4868236 0.122 0.003 1.000000e+00 CTL_MUT
## Cacna2d3 2.436283e-03 0.6066327 0.357 0.357 1.000000e+00 CTL_MUT
## Col19a1 2.463120e-03 -4.7963799 0.194 0.122 1.000000e+00 CTL_MUT
## Kif23 2.509030e-03 -0.3845791 0.126 0.007 1.000000e+00 CTL_MUT
## Pcp4 2.855500e-03 -3.3877736 0.249 0.289 1.000000e+00 CTL_MUT
## Asrgl1 2.984462e-03 -1.5496549 0.222 0.184 1.000000e+00 CTL_MUT
## Klhl1 3.046423e-03 -6.2386461 0.165 0.033 1.000000e+00 CTL_MUT
## Scg2 3.438291e-03 -2.2710998 0.175 0.151 1.000000e+00 CTL_MUT
## Socs3 3.501261e-03 -6.3780127 0.155 0.007 1.000000e+00 CTL_MUT
## Lag3 3.687139e-03 -1.0558548 0.160 0.009 1.000000e+00 CTL_MUT
## Pld5 4.120620e-03 -4.8629563 0.128 0.030 1.000000e+00 CTL_MUT
## Fth1 4.247799e-03 -4.2041666 0.316 0.344 1.000000e+00 CTL_MUT
## Igf2 4.269453e-03 -1.2105872 0.177 0.009 1.000000e+00 CTL_MUT
## Ccrl2 4.515558e-03 -1.5319011 0.115 0.008 1.000000e+00 CTL_MUT
## Ttll8 4.627892e-03 7.4041778 0.121 0.019 1.000000e+00 CTL_MUT
## Dmrta2 5.243223e-03 -5.9853452 0.222 0.009 1.000000e+00 CTL_MUT
## Tlr3 5.574896e-03 -11.1736172 0.174 0.024 1.000000e+00 CTL_MUT
## Vwc2 5.753032e-03 -2.6237793 0.135 0.032 1.000000e+00 CTL_MUT
## Hspg2 5.889029e-03 -3.2159886 0.158 0.008 1.000000e+00 CTL_MUT
## Pde3a 6.018062e-03 -1.6122167 0.162 0.020 1.000000e+00 CTL_MUT
## Fibin 6.084540e-03 -1.9947611 0.181 0.005 1.000000e+00 CTL_MUT
## Timp3 6.454892e-03 -3.0440213 0.205 0.169 1.000000e+00 CTL_MUT
## Trim12c 6.550507e-03 -5.6477438 0.160 0.007 1.000000e+00 CTL_MUT
## Tcerg1l 7.246150e-03 6.7657131 0.151 0.034 1.000000e+00 CTL_MUT
## Aspn 7.267810e-03 0.5938597 0.136 0.006 1.000000e+00 CTL_MUT
## Trim12a 7.482462e-03 -0.2674306 0.135 0.009 1.000000e+00 CTL_MUT
## Olfml2a 8.320924e-03 4.0161564 0.150 0.010 1.000000e+00 CTL_MUT
## Gulp1 8.916040e-03 -8.4144631 0.174 0.026 1.000000e+00 CTL_MUT
## Kctd8 9.040282e-03 -8.2089044 0.168 0.077 1.000000e+00 CTL_MUT
## Sorbs2os 9.194384e-03 -2.0915994 0.206 0.145 1.000000e+00 CTL_MUT
## Gpx3 1.004055e-02 -1.0341772 0.181 0.006 1.000000e+00 CTL_MUT
## Hhip 1.004785e-02 -8.4241731 0.128 0.025 1.000000e+00 CTL_MUT
## Ldha 1.096568e-02 0.8907542 0.197 0.274 1.000000e+00 CTL_MUT
## Golm1 1.116038e-02 -1.9087447 0.136 0.061 1.000000e+00 CTL_MUT
## Synpr 1.164940e-02 -1.7452586 0.212 0.178 1.000000e+00 CTL_MUT
## Gm50394 1.200577e-02 5.7838172 0.143 0.003 1.000000e+00 CTL_MUT
## Syt6 1.290483e-02 6.3946705 0.142 0.040 1.000000e+00 CTL_MUT
## Pf4 1.297001e-02 -1.7010341 0.116 0.006 1.000000e+00 CTL_MUT
## Snorc 1.309948e-02 -1.8787585 0.141 0.004 1.000000e+00 CTL_MUT
## Gm49906 1.352191e-02 -2.1598075 0.172 0.010 1.000000e+00 CTL_MUT
## Cst3 1.395379e-02 -2.4039462 0.293 0.325 1.000000e+00 CTL_MUT
## Cenpm 1.398589e-02 -3.1407550 0.159 0.009 1.000000e+00 CTL_MUT
## Usp53 1.406787e-02 2.8071908 0.171 0.107 1.000000e+00 CTL_MUT
## Nhs 1.567994e-02 0.8760409 0.132 0.053 1.000000e+00 CTL_MUT
## Tgfbr1 1.569074e-02 -0.8786765 0.119 0.089 1.000000e+00 CTL_MUT
## Mkrn3 1.574230e-02 -3.1540678 0.130 0.002 1.000000e+00 CTL_MUT
## 4930445B16Rik 1.583408e-02 -3.4455587 0.159 0.047 1.000000e+00 CTL_MUT
## Fblim1 1.637316e-02 -5.6110444 0.138 0.004 1.000000e+00 CTL_MUT
## Ifngr1 1.640531e-02 10.9518344 0.160 0.032 1.000000e+00 CTL_MUT
## Opalin 1.642778e-02 -1.1848387 0.146 0.084 1.000000e+00 CTL_MUT
## Cyth4 1.686918e-02 0.5989130 0.124 0.014 1.000000e+00 CTL_MUT
## Uaca 1.713068e-02 3.9101445 0.143 0.012 1.000000e+00 CTL_MUT
## Col9a3 1.726458e-02 -0.7022725 0.173 0.023 1.000000e+00 CTL_MUT
## Camk2d 1.744843e-02 1.0470778 0.276 0.297 1.000000e+00 CTL_MUT
## Gm13974 1.767375e-02 0.2599818 0.191 0.006 1.000000e+00 CTL_MUT
## Uba7 1.775783e-02 -1.2849995 0.130 0.003 1.000000e+00 CTL_MUT
## Gm29570 1.784734e-02 -2.8389698 0.111 0.001 1.000000e+00 CTL_MUT
## Eva1a 1.799476e-02 -5.5290022 0.151 0.042 1.000000e+00 CTL_MUT
## Acss3 1.849218e-02 -0.8145404 0.135 0.006 1.000000e+00 CTL_MUT
## Col7a1 1.919282e-02 -6.2508304 0.134 0.003 1.000000e+00 CTL_MUT
## Gm16070 1.973659e-02 -13.3415685 0.101 0.008 1.000000e+00 CTL_MUT
## Gm37876 2.047389e-02 -3.2125105 0.126 0.003 1.000000e+00 CTL_MUT
## Rhou 2.057634e-02 -2.9073311 0.208 0.145 1.000000e+00 CTL_MUT
## Gas1 2.112131e-02 -2.7063574 0.166 0.016 1.000000e+00 CTL_MUT
## Sgo2a 2.150344e-02 -3.5831711 0.119 0.004 1.000000e+00 CTL_MUT
## Gm30382 2.356281e-02 -0.5311761 0.201 0.125 1.000000e+00 CTL_MUT
## 2310067P03Rik 2.364770e-02 -1.6407840 0.140 0.004 1.000000e+00 CTL_MUT
## C78334 2.443757e-02 3.0059332 0.131 0.003 1.000000e+00 CTL_MUT
## Fhit 2.777183e-02 0.3691562 0.249 0.180 1.000000e+00 CTL_MUT
## Gm6994 2.814060e-02 -3.7802807 0.185 0.030 1.000000e+00 CTL_MUT
## Zfp185 2.887362e-02 5.8967961 0.121 0.003 1.000000e+00 CTL_MUT
## Kctd16 3.062530e-02 -2.5657981 0.363 0.375 1.000000e+00 CTL_MUT
## Alox5ap 3.070745e-02 -0.2788157 0.149 0.017 1.000000e+00 CTL_MUT
## AU020206 3.191688e-02 -0.2739230 0.120 0.007 1.000000e+00 CTL_MUT
## Trpc6 3.297612e-02 -1.3375234 0.133 0.060 1.000000e+00 CTL_MUT
## Tuba1a 3.353066e-02 -5.7374274 0.376 0.412 1.000000e+00 CTL_MUT
## Hcst 3.666371e-02 -4.4971830 0.166 0.003 1.000000e+00 CTL_MUT
## Agmo 3.671733e-02 -7.4182815 0.130 0.073 1.000000e+00 CTL_MUT
## Chrm2 3.863647e-02 11.4480292 0.162 0.077 1.000000e+00 CTL_MUT
## Msx1 4.159566e-02 0.4135543 0.137 0.004 1.000000e+00 CTL_MUT
## Lap3 4.549995e-02 -4.3163365 0.170 0.065 1.000000e+00 CTL_MUT
## Chrdl1 4.847053e-02 5.9120897 0.180 0.030 1.000000e+00 CTL_MUT
## Cnr1 4.892866e-02 -1.9880823 0.179 0.182 1.000000e+00 CTL_MUT
## Hapln2 5.010671e-02 0.5001435 0.110 0.018 1.000000e+00 CTL_MUT
## Trp53inp1 5.175303e-02 -2.9309253 0.168 0.051 1.000000e+00 CTL_MUT
## Spp1 5.239202e-02 -2.1168995 0.159 0.009 1.000000e+00 CTL_MUT
## Mis18bp1 5.261519e-02 -3.1235026 0.101 0.005 1.000000e+00 CTL_MUT
## C3ar1 5.315425e-02 -1.2363454 0.106 0.013 1.000000e+00 CTL_MUT
## Gm28905 5.633208e-02 -3.0307585 0.202 0.131 1.000000e+00 CTL_MUT
## Spag16 5.715327e-02 -0.7827090 0.160 0.013 1.000000e+00 CTL_MUT
## Fas 5.888004e-02 1.1806215 0.126 0.012 1.000000e+00 CTL_MUT
## Tcf7 6.126697e-02 -2.7149404 0.156 0.007 1.000000e+00 CTL_MUT
## Sytl1 6.216801e-02 -1.4276053 0.153 0.003 1.000000e+00 CTL_MUT
## Thsd7b 6.332913e-02 0.8419533 0.198 0.120 1.000000e+00 CTL_MUT
## Slc1a2 6.410036e-02 1.1997827 0.366 0.377 1.000000e+00 CTL_MUT
## Gm45904 6.487327e-02 -5.7915335 0.168 0.022 1.000000e+00 CTL_MUT
## Kcnip1 6.530402e-02 -0.5888496 0.128 0.092 1.000000e+00 CTL_MUT
## Tgfbr2 6.810062e-02 -0.8140367 0.123 0.033 1.000000e+00 CTL_MUT
## Schip1 7.190040e-02 -0.9283398 0.366 0.368 1.000000e+00 CTL_MUT
## Hpca 7.523967e-02 0.4640005 0.174 0.291 1.000000e+00 CTL_MUT
## Gm48678 7.585458e-02 -5.2779379 0.211 0.116 1.000000e+00 CTL_MUT
## Ror1 7.642466e-02 -0.4314368 0.141 0.026 1.000000e+00 CTL_MUT
## Ttc36 7.942024e-02 0.5842378 0.109 0.002 1.000000e+00 CTL_MUT
## Sema3d 8.050476e-02 -11.4309424 0.122 0.035 1.000000e+00 CTL_MUT
## Atp1a1 8.553489e-02 -0.7303892 0.373 0.411 1.000000e+00 CTL_MUT
## Gm36266 8.602195e-02 -2.5243282 0.109 0.001 1.000000e+00 CTL_MUT
## Ramp2 8.759304e-02 -5.3056374 0.130 0.110 1.000000e+00 CTL_MUT
## Ccdc163 8.980942e-02 -1.9478808 0.225 0.006 1.000000e+00 CTL_MUT
## Gab2 9.099597e-02 -3.9764882 0.213 0.142 1.000000e+00 CTL_MUT
## Gsap 9.220699e-02 5.4854007 0.198 0.023 1.000000e+00 CTL_MUT
## Slc25a13 9.286927e-02 0.3907115 0.148 0.024 1.000000e+00 CTL_MUT
## Rph3al 9.314915e-02 -3.1939995 0.122 0.003 1.000000e+00 CTL_MUT
## Slc13a3 9.646392e-02 -2.5067083 0.151 0.007 1.000000e+00 CTL_MUT
## Plekhf1 9.694050e-02 -8.0420690 0.179 0.010 1.000000e+00 CTL_MUT
## Smagp 9.753727e-02 1.5113586 0.148 0.007 1.000000e+00 CTL_MUT
## Aox2 9.756290e-02 1.3195436 0.171 0.002 1.000000e+00 CTL_MUT
## Zfp804b 9.816983e-02 -2.3190159 0.215 0.166 1.000000e+00 CTL_MUT
## Pde3b 9.849616e-02 -6.6643115 0.154 0.111 1.000000e+00 CTL_MUT
## Vamp8 1.028422e-01 5.3298211 0.158 0.027 1.000000e+00 CTL_MUT
## Cd74 1.046956e-01 -1.9268434 0.155 0.004 1.000000e+00 CTL_MUT
## Gm4577 1.074198e-01 -1.1489912 0.125 0.002 1.000000e+00 CTL_MUT
## Ly75 1.082016e-01 -5.9055536 0.107 0.006 1.000000e+00 CTL_MUT
## Cdh5 1.093871e-01 -1.9434687 0.102 0.015 1.000000e+00 CTL_MUT
## 1700023F02Rik 1.114208e-01 -3.3533603 0.142 0.046 1.000000e+00 CTL_MUT
## Gm44995 1.141159e-01 0.3872475 0.126 0.003 1.000000e+00 CTL_MUT
## Hebp2 1.148941e-01 8.0598508 0.158 0.004 1.000000e+00 CTL_MUT
## 4930419G24Rik 1.152153e-01 -6.5722177 0.194 0.071 1.000000e+00 CTL_MUT
## C030029H02Rik 1.173019e-01 -1.1999964 0.133 0.015 1.000000e+00 CTL_MUT
## Pdpn 1.185322e-01 -1.3579537 0.181 0.011 1.000000e+00 CTL_MUT
## Fstl5 1.190740e-01 4.2621264 0.184 0.101 1.000000e+00 CTL_MUT
## Lcat 1.243781e-01 -3.3287900 0.179 0.023 1.000000e+00 CTL_MUT
## Lbhd2 1.281923e-01 -1.0990655 0.122 0.002 1.000000e+00 CTL_MUT
## Gm20752 1.304108e-01 -2.6060287 0.138 0.032 1.000000e+00 CTL_MUT
## Fibcd1 1.340646e-01 -1.3763631 0.153 0.004 1.000000e+00 CTL_MUT
## Mroh3 1.355372e-01 -2.6371041 0.117 0.003 1.000000e+00 CTL_MUT
## Mfng 1.365654e-01 -9.6696077 0.134 0.005 1.000000e+00 CTL_MUT
## Nxph1 1.373873e-01 -0.2706765 0.190 0.147 1.000000e+00 CTL_MUT
## Sp9 1.384376e-01 -3.3458257 0.149 0.012 1.000000e+00 CTL_MUT
## Adamts12 1.462974e-01 -1.3216901 0.128 0.003 1.000000e+00 CTL_MUT
## Ehd4 1.481389e-01 -2.8678549 0.159 0.022 1.000000e+00 CTL_MUT
## Tns2 1.637457e-01 -1.8898948 0.153 0.011 1.000000e+00 CTL_MUT
## Lingo2 1.639720e-01 1.2722433 0.380 0.374 1.000000e+00 CTL_MUT
## Mtmr11 1.658305e-01 -6.5161752 0.207 0.007 1.000000e+00 CTL_MUT
## Gm34408 1.779549e-01 -1.3542250 0.122 0.003 1.000000e+00 CTL_MUT
## 8030451A03Rik 1.794367e-01 -3.2199741 0.102 0.002 1.000000e+00 CTL_MUT
## Rasgrf2 1.805719e-01 1.2711240 0.253 0.235 1.000000e+00 CTL_MUT
## Bsg 1.810489e-01 2.9853348 0.338 0.395 1.000000e+00 CTL_MUT
## Thsd7a 1.896519e-01 -3.9873844 0.198 0.129 1.000000e+00 CTL_MUT
## Gja1 1.903751e-01 -0.8636764 0.219 0.176 1.000000e+00 CTL_MUT
## Dmp1 1.909837e-01 -3.8485477 0.177 0.004 1.000000e+00 CTL_MUT
## Gpr37 1.989639e-01 -5.4829244 0.133 0.047 1.000000e+00 CTL_MUT
## E130114P18Rik 2.054546e-01 -8.1306190 0.171 0.035 1.000000e+00 CTL_MUT
## Adgrg1 2.100544e-01 -0.5442602 0.176 0.041 1.000000e+00 CTL_MUT
## Gm43154 2.124593e-01 -9.3520115 0.155 0.017 1.000000e+00 CTL_MUT
## Eps8l3 2.233333e-01 -2.0732319 0.131 0.002 1.000000e+00 CTL_MUT
## Crym 2.238700e-01 1.3205069 0.146 0.155 1.000000e+00 CTL_MUT
## Zfp677 2.256948e-01 0.7838023 0.132 0.003 1.000000e+00 CTL_MUT
## Lama3 2.271184e-01 0.8173283 0.146 0.011 1.000000e+00 CTL_MUT
## Rasgrp2 2.286324e-01 -4.4227077 0.131 0.035 1.000000e+00 CTL_MUT
## Syndig1l 2.316469e-01 -1.0892198 0.117 0.002 1.000000e+00 CTL_MUT
## Egfl6 2.321120e-01 -3.0591343 0.164 0.003 1.000000e+00 CTL_MUT
## Trbc2 2.324230e-01 5.9734310 0.137 0.089 1.000000e+00 CTL_MUT
## Hist1h1e 2.376845e-01 3.3456921 0.156 0.032 1.000000e+00 CTL_MUT
## Fam102b 2.454953e-01 -5.2298440 0.158 0.072 1.000000e+00 CTL_MUT
## Ppp1r36 2.509310e-01 -1.5422467 0.122 0.002 1.000000e+00 CTL_MUT
## Slc7a7 2.545494e-01 -2.2957361 0.121 0.007 1.000000e+00 CTL_MUT
## Rerg 2.605750e-01 -1.4650510 0.134 0.009 1.000000e+00 CTL_MUT
## Colec12 2.616388e-01 -3.3847433 0.116 0.023 1.000000e+00 CTL_MUT
## Gem 2.629142e-01 -2.1966583 0.157 0.008 1.000000e+00 CTL_MUT
## Gm19303 2.691814e-01 -1.0975201 0.121 0.003 1.000000e+00 CTL_MUT
## Apoc1 2.718201e-01 -1.4890691 0.136 0.002 1.000000e+00 CTL_MUT
## Cd52 2.767271e-01 -7.8279091 0.199 0.009 1.000000e+00 CTL_MUT
## Mhrt 2.784052e-01 0.4076027 0.121 0.004 1.000000e+00 CTL_MUT
## Pard3bos1 2.795024e-01 -0.2614057 0.117 0.003 1.000000e+00 CTL_MUT
## Gm47095 2.868182e-01 3.8269128 0.150 0.003 1.000000e+00 CTL_MUT
## G0s2 2.889616e-01 -7.6703116 0.170 0.035 1.000000e+00 CTL_MUT
## Sln 2.895727e-01 -3.3110781 0.123 0.006 1.000000e+00 CTL_MUT
## Cd38 3.150557e-01 3.5489658 0.152 0.010 1.000000e+00 CTL_MUT
## Ccl9 3.174584e-01 -2.9639808 0.128 0.008 1.000000e+00 CTL_MUT
## Lpar1 3.212234e-01 -10.1648011 0.166 0.073 1.000000e+00 CTL_MUT
## Kif20b 3.219120e-01 0.4105570 0.120 0.005 1.000000e+00 CTL_MUT
## Galnt14 3.266914e-01 -8.2668481 0.155 0.072 1.000000e+00 CTL_MUT
## Gm48321 3.273708e-01 -3.8538617 0.158 0.064 1.000000e+00 CTL_MUT
## Ppic 3.326524e-01 11.0750103 0.107 0.007 1.000000e+00 CTL_MUT
## Mmrn2 3.344772e-01 -2.5353437 0.119 0.006 1.000000e+00 CTL_MUT
## E2f7 3.560771e-01 -6.3942975 0.124 0.003 1.000000e+00 CTL_MUT
## Slc17a8 3.575600e-01 -1.4385739 0.113 0.005 1.000000e+00 CTL_MUT
## Nell1 3.584450e-01 -1.5789760 0.214 0.116 1.000000e+00 CTL_MUT
## Neu4 3.607335e-01 6.3463338 0.128 0.016 1.000000e+00 CTL_MUT
## Efemp1 3.654963e-01 -9.4183309 0.188 0.010 1.000000e+00 CTL_MUT
## Nphs1 3.707310e-01 1.6656510 0.145 0.010 1.000000e+00 CTL_MUT
## Tmsb10 3.805815e-01 -1.6031564 0.326 0.342 1.000000e+00 CTL_MUT
## P3h2 3.825887e-01 -2.8031270 0.142 0.047 1.000000e+00 CTL_MUT
## Gm26713 3.844919e-01 -4.8200743 0.141 0.004 1.000000e+00 CTL_MUT
## Dnah12 3.851040e-01 -1.8997056 0.105 0.004 1.000000e+00 CTL_MUT
## Gm36372 3.896056e-01 -2.9995334 0.101 0.002 1.000000e+00 CTL_MUT
## Hs6st2 3.917004e-01 3.5251990 0.186 0.125 1.000000e+00 CTL_MUT
## Prokr2 3.954350e-01 0.5412193 0.104 0.004 1.000000e+00 CTL_MUT
## Cartpt 3.982899e-01 -0.8325100 0.149 0.010 1.000000e+00 CTL_MUT
## Hmgb1 4.117779e-01 -0.3289196 0.393 0.433 1.000000e+00 CTL_MUT
## Ddah1 4.123603e-01 0.4209509 0.208 0.171 1.000000e+00 CTL_MUT
## Ncf2 4.133991e-01 -5.0100178 0.129 0.012 1.000000e+00 CTL_MUT
## Prdx2 4.146592e-01 -0.4451878 0.313 0.337 1.000000e+00 CTL_MUT
## Dock5 4.156445e-01 -1.0789983 0.157 0.015 1.000000e+00 CTL_MUT
## Cacna2d2 4.205455e-01 -1.5603247 0.181 0.037 1.000000e+00 CTL_MUT
## Pparg 4.370604e-01 -2.6889074 0.163 0.090 1.000000e+00 CTL_MUT
## Igfbp3 4.393914e-01 -1.1306167 0.161 0.013 1.000000e+00 CTL_MUT
## Sntb1 4.404824e-01 -0.5859357 0.132 0.010 1.000000e+00 CTL_MUT
## Birc3 4.421744e-01 -4.2444242 0.161 0.008 1.000000e+00 CTL_MUT
## Kcnh8 4.555032e-01 -2.7091215 0.120 0.017 1.000000e+00 CTL_MUT
## Aurka 4.570627e-01 6.7858233 0.101 0.003 1.000000e+00 CTL_MUT
## Cenpk 4.611131e-01 -10.0525696 0.177 0.008 1.000000e+00 CTL_MUT
## Htr2c 4.621590e-01 -1.2351901 0.100 0.042 1.000000e+00 CTL_MUT
## Gm29506 4.643715e-01 -2.9396748 0.132 0.003 1.000000e+00 CTL_MUT
## Prc1 4.667345e-01 3.4288779 0.106 0.013 1.000000e+00 CTL_MUT
## Mag 4.672915e-01 2.8315563 0.211 0.147 1.000000e+00 CTL_MUT
## Olfm3 4.677437e-01 -1.6465188 0.192 0.110 1.000000e+00 CTL_MUT
## Myzap 4.703406e-01 -2.9713563 0.102 0.004 1.000000e+00 CTL_MUT
## Apoe 4.703929e-01 -0.8205485 0.331 0.341 1.000000e+00 CTL_MUT
## Nmral1 4.727409e-01 -11.8608411 0.155 0.028 1.000000e+00 CTL_MUT
## Bcl2a1b 4.803112e-01 0.8185751 0.150 0.011 1.000000e+00 CTL_MUT
## Sparcl1 4.813936e-01 3.2566463 0.397 0.391 1.000000e+00 CTL_MUT
## Esm1 4.823652e-01 -1.8706382 0.116 0.002 1.000000e+00 CTL_MUT
## Zc3h12a 4.824603e-01 3.2659630 0.153 0.003 1.000000e+00 CTL_MUT
## Vstm4 4.844183e-01 -1.7337443 0.164 0.005 1.000000e+00 CTL_MUT
## Gm30075 4.881899e-01 2.4060278 0.151 0.002 1.000000e+00 CTL_MUT
## Gm32509 5.003586e-01 0.5953680 0.190 0.092 1.000000e+00 CTL_MUT
## S100a10 5.161351e-01 -1.1825044 0.139 0.101 1.000000e+00 CTL_MUT
## Traf3ip3 5.190053e-01 -2.4644343 0.123 0.003 1.000000e+00 CTL_MUT
## Sec14l5 5.340143e-01 -6.7247057 0.133 0.026 1.000000e+00 CTL_MUT
## Smoc2 5.369444e-01 -1.3748683 0.118 0.048 1.000000e+00 CTL_MUT
## Celsr1 5.481074e-01 -1.0289348 0.162 0.005 1.000000e+00 CTL_MUT
## Brca1 5.564615e-01 -1.9658696 0.144 0.007 1.000000e+00 CTL_MUT
## Tns3 5.617269e-01 -2.3315324 0.142 0.079 1.000000e+00 CTL_MUT
## Gm47771 5.675754e-01 -2.2309388 0.164 0.003 1.000000e+00 CTL_MUT
## Adamtsl3 5.778172e-01 -3.6847492 0.194 0.006 1.000000e+00 CTL_MUT
## Cyp2j9 5.824694e-01 -2.1219103 0.156 0.025 1.000000e+00 CTL_MUT
## Lsr 6.147035e-01 -3.7995523 0.132 0.013 1.000000e+00 CTL_MUT
## Car8 6.149704e-01 -7.2733468 0.182 0.017 1.000000e+00 CTL_MUT
## 2310002F09Rik 6.185126e-01 -2.1834097 0.140 0.003 1.000000e+00 CTL_MUT
## Rgs20 6.260297e-01 8.0532836 0.214 0.170 1.000000e+00 CTL_MUT
## Itgbl1 6.361504e-01 -1.8304399 0.182 0.050 1.000000e+00 CTL_MUT
## Trim16 6.463281e-01 -2.6791599 0.127 0.005 1.000000e+00 CTL_MUT
## Ddc 6.586308e-01 -0.4467207 0.153 0.023 1.000000e+00 CTL_MUT
## Kcnb2 6.625870e-01 1.0111305 0.363 0.374 1.000000e+00 CTL_MUT
## Trp53i11 6.769114e-01 -7.6344725 0.168 0.048 1.000000e+00 CTL_MUT
## Ndst4 6.796977e-01 -0.6901913 0.148 0.016 1.000000e+00 CTL_MUT
## Car10 7.096313e-01 -0.7379108 0.370 0.381 1.000000e+00 CTL_MUT
## Cttnbp2nl 7.268149e-01 1.1823220 0.165 0.065 1.000000e+00 CTL_MUT
## S1pr1 7.283125e-01 3.9107734 0.185 0.168 1.000000e+00 CTL_MUT
## S100a6 7.330046e-01 -13.2276272 0.171 0.093 1.000000e+00 CTL_MUT
## Stac 7.392891e-01 -0.9233639 0.156 0.007 1.000000e+00 CTL_MUT
## Pycr1 7.441996e-01 -0.9650369 0.144 0.004 1.000000e+00 CTL_MUT
## Slc35d2 7.491602e-01 3.3637326 0.135 0.003 1.000000e+00 CTL_MUT
## Prlr 7.545817e-01 -1.7218781 0.172 0.003 1.000000e+00 CTL_MUT
## Tnnt1 7.551437e-01 1.9362212 0.147 0.004 1.000000e+00 CTL_MUT
## Pole2 7.557432e-01 2.5285061 0.182 0.003 1.000000e+00 CTL_MUT
## Tenm2 7.772762e-01 1.6667149 0.393 0.387 1.000000e+00 CTL_MUT
## Gimap6 7.851769e-01 2.3870093 0.112 0.017 1.000000e+00 CTL_MUT
## Gm4876 7.887260e-01 -4.4411929 0.156 0.099 1.000000e+00 CTL_MUT
## S100a4 8.039138e-01 -0.9732565 0.209 0.008 1.000000e+00 CTL_MUT
## Yjefn3 8.159108e-01 3.0381124 0.154 0.045 1.000000e+00 CTL_MUT
## Gm26512 8.182261e-01 -1.2789599 0.128 0.051 1.000000e+00 CTL_MUT
## Eya2 8.182751e-01 -1.8687437 0.147 0.007 1.000000e+00 CTL_MUT
## Mmp28 8.228096e-01 -2.7728131 0.166 0.004 1.000000e+00 CTL_MUT
## Cd33 8.313697e-01 -0.9198857 0.123 0.016 1.000000e+00 CTL_MUT
## Gm12648 8.402936e-01 -2.3408348 0.125 0.002 1.000000e+00 CTL_MUT
## Sh3d21 8.472236e-01 -2.2460603 0.151 0.004 1.000000e+00 CTL_MUT
## Cep72 8.552370e-01 -6.3267954 0.171 0.004 1.000000e+00 CTL_MUT
## Fbxo5 8.797939e-01 -0.7355582 0.101 0.004 1.000000e+00 CTL_MUT
## Esyt3 8.840067e-01 2.9149554 0.152 0.003 1.000000e+00 CTL_MUT
## Lamc3 8.979150e-01 -1.9798175 0.116 0.007 1.000000e+00 CTL_MUT
## Rbms3 9.269442e-01 -10.1661927 0.212 0.168 1.000000e+00 CTL_MUT
## Pecam1 9.270479e-01 2.1535594 0.103 0.022 1.000000e+00 CTL_MUT
## Ly6g6d 9.271843e-01 2.5153920 0.148 0.003 1.000000e+00 CTL_MUT
## Cdh4 9.399771e-01 12.3371198 0.174 0.093 1.000000e+00 CTL_MUT
## Loxl3 9.465605e-01 3.0007071 0.104 0.004 1.000000e+00 CTL_MUT
## Cdk2 9.493561e-01 1.5502010 0.116 0.003 1.000000e+00 CTL_MUT
## Arhgap6 9.512000e-01 -3.3248863 0.154 0.025 1.000000e+00 CTL_MUT
## Cenpe 9.596036e-01 0.5839235 0.109 0.007 1.000000e+00 CTL_MUT
## Kcnip4 9.656325e-01 2.6256401 0.412 0.406 1.000000e+00 CTL_MUT
## Ms4a6b 9.847103e-01 0.4291760 0.118 0.007 1.000000e+00 CTL_MUT
## Actb 9.939651e-01 5.7207845 0.380 0.411 1.000000e+00 CTL_MUT
## Draxin 9.999291e-01 -0.9036926 0.132 0.004 1.000000e+00 CTL_MUTDifferential expression Analysis for cluster between groups
Next we will do DEG for each cluster betweent the two groups, and write the results to a csv file
Quatitative analysis of DEGs by each cluster
MAPK pathway gene plotting
Because we are interested in the MAPK1 pathway, we select relevant genes for plotting
