| DerosaL_2022 (N=338) |
FrankelAE_2017 (N=39) |
GopalakrishnanV_2018 (N=25) |
LeeKA_2022 (N=165) |
MatsonV_2018 (N=39) |
McCullochJA_2022 (N=63) |
PengZ_2020 (N=40) |
PetersBA_2019 (N=27) |
RoutyB_2018 (N=153) |
SpencerCN_2021 (N=158) |
Overall (N=1047) |
|
|---|---|---|---|---|---|---|---|---|---|---|---|
| Age | |||||||||||
| Mean (SD) | 64.8 (9.74) | 66.0 (13.0) | 67.9 (15.2) | 61.0 (14.5) | NA (NA) | 67.6 (12.8) | NA (NA) | 70.3 (11.9) | 63.0 (9.15) | 64.7 (12.0) | 64.3 (11.7) |
| Median [Min, Max] | 65.0 [24.0, 92.0] | 68.0 [37.0, 92.0] | 71.0 [21.0, 88.0] | 60.0 [15.0, 90.0] | NA [NA, NA] | 66.8 [32.0, 89.5] | NA [NA, NA] | 71.7 [47.4, 90.6] | 63.0 [41.0, 82.0] | 66.0 [36.0, 88.0] | 65.0 [15.0, 92.0] |
| Missing | 0 (0%) | 0 (0%) | 1 (4.0%) | 2 (1.2%) | 39 (100%) | 0 (0%) | 40 (100%) | 0 (0%) | 0 (0%) | 1 (0.6%) | 83 (7.9%) |
| Gender | |||||||||||
| female | 112 (33.1%) | 9 (23.1%) | 0 (0%) | 65 (39.4%) | 0 (0%) | 21 (33.3%) | 0 (0%) | 6 (22.2%) | 48 (31.4%) | 55 (34.8%) | 316 (30.2%) |
| male | 226 (66.9%) | 30 (76.9%) | 0 (0%) | 100 (60.6%) | 0 (0%) | 42 (66.7%) | 0 (0%) | 21 (77.8%) | 105 (68.6%) | 103 (65.2%) | 627 (59.9%) |
| Female | 0 (0%) | 0 (0%) | 9 (36.0%) | 0 (0%) | 0 (0%) | 0 (0%) | 0 (0%) | 0 (0%) | 0 (0%) | 0 (0%) | 9 (0.9%) |
| Male | 0 (0%) | 0 (0%) | 16 (64.0%) | 0 (0%) | 0 (0%) | 0 (0%) | 0 (0%) | 0 (0%) | 0 (0%) | 0 (0%) | 16 (1.5%) |
| Missing | 0 (0%) | 0 (0%) | 0 (0%) | 0 (0%) | 39 (100%) | 0 (0%) | 40 (100%) | 0 (0%) | 0 (0%) | 0 (0%) | 79 (7.5%) |
| BMI | |||||||||||
| Mean (SD) | 24.2 (4.30) | NA (NA) | NA (NA) | 26.5 (8.60) | NA (NA) | 30.4 (6.45) | NA (NA) | 27.5 (4.77) | NA (NA) | 30.5 (6.41) | 26.7 (6.67) |
| Median [Min, Max] | 24.0 [15.4, 39.9] | NA [NA, NA] | NA [NA, NA] | 27.4 [0, 57.7] | NA [NA, NA] | 30.1 [18.0, 43.1] | NA [NA, NA] | 27.8 [18.3, 38.8] | NA [NA, NA] | 29.0 [19.0, 52.0] | 26.0 [0, 57.7] |
| Missing | 4 (1.2%) | 39 (100%) | 25 (100%) | 0 (0%) | 39 (100%) | 0 (0%) | 40 (100%) | 0 (0%) | 153 (100%) | 0 (0%) | 300 (28.7%) |
| Antibiotics | |||||||||||
| no | 269 (79.6%) | 0 (0%) | 0 (0%) | 136 (82.4%) | 0 (0%) | 57 (90.5%) | 0 (0%) | 22 (81.5%) | 121 (79.1%) | 80 (50.6%) | 685 (65.4%) |
| yes | 69 (20.4%) | 0 (0%) | 0 (0%) | 26 (15.8%) | 0 (0%) | 6 (9.5%) | 0 (0%) | 5 (18.5%) | 32 (20.9%) | 31 (19.6%) | 169 (16.1%) |
| Missing | 0 (0%) | 39 (100%) | 25 (100%) | 3 (1.8%) | 39 (100%) | 0 (0%) | 40 (100%) | 0 (0%) | 0 (0%) | 47 (29.7%) | 193 (18.4%) |
| Cancers | |||||||||||
| NSCLC | 338 (100%) | 0 (0%) | 0 (0%) | 0 (0%) | 0 (0%) | 0 (0%) | 0 (0%) | 0 (0%) | 81 (52.9%) | 0 (0%) | 419 (40.0%) |
| Melanoma | 0 (0%) | 39 (100%) | 25 (100%) | 165 (100%) | 39 (100%) | 63 (100%) | 0 (0%) | 27 (100%) | 0 (0%) | 158 (100%) | 516 (49.3%) |
| GI | 0 (0%) | 0 (0%) | 0 (0%) | 0 (0%) | 0 (0%) | 0 (0%) | 40 (100%) | 0 (0%) | 0 (0%) | 0 (0%) | 40 (3.8%) |
| RCC | 0 (0%) | 0 (0%) | 0 (0%) | 0 (0%) | 0 (0%) | 0 (0%) | 0 (0%) | 0 (0%) | 72 (47.1%) | 0 (0%) | 72 (6.9%) |
| Response | |||||||||||
| NR | 263 (77.8%) | 15 (38.5%) | 11 (44.0%) | 71 (43.0%) | 24 (61.5%) | 25 (39.7%) | 15 (37.5%) | 15 (55.6%) | 67 (43.8%) | 58 (36.7%) | 564 (53.9%) |
| R | 75 (22.2%) | 24 (61.5%) | 14 (56.0%) | 94 (57.0%) | 15 (38.5%) | 38 (60.3%) | 25 (62.5%) | 12 (44.4%) | 86 (56.2%) | 100 (63.3%) | 483 (46.1%) |
| AvgSpotLen | |||||||||||
| Mean (SD) | 152 (18.2) | 200 (4.89) | 201 (0.332) | 296 (5.68) | 300 (0.818) | 298 (0.679) | 300 (0) | 202 (0) | 137 (7.64) | 246 (45.9) | 211 (68.9) |
| Median [Min, Max] | 145 [114, 183] | 199 [189, 210] | 201 [200, 201] | 298 [253, 300] | 300 [297, 301] | 298 [296, 299] | 300 [300, 300] | 202 [202, 202] | 139 [122, 154] | 286 [193, 295] | 196 [114, 301] |
| LibraryLayout | |||||||||||
| SINGLE | 338 (100%) | 0 (0%) | 0 (0%) | 0 (0%) | 0 (0%) | 0 (0%) | 0 (0%) | 0 (0%) | 153 (100%) | 0 (0%) | 491 (46.9%) |
| PAIRED | 0 (0%) | 39 (100%) | 25 (100%) | 165 (100%) | 39 (100%) | 63 (100%) | 40 (100%) | 27 (100%) | 0 (0%) | 158 (100%) | 556 (53.1%) |
| Platform | |||||||||||
| ION_TORRENT | 338 (100%) | 0 (0%) | 0 (0%) | 0 (0%) | 0 (0%) | 0 (0%) | 0 (0%) | 0 (0%) | 153 (100%) | 0 (0%) | 491 (46.9%) |
| ILLUMINA | 0 (0%) | 39 (100%) | 25 (100%) | 165 (100%) | 39 (100%) | 63 (100%) | 40 (100%) | 27 (100%) | 0 (0%) | 158 (100%) | 556 (53.1%) |
| Country | |||||||||||
| France | 338 (100%) | 0 (0%) | 0 (0%) | 0 (0%) | 0 (0%) | 0 (0%) | 0 (0%) | 0 (0%) | 153 (100%) | 0 (0%) | 491 (46.9%) |
| USA | 0 (0%) | 39 (100%) | 25 (100%) | 0 (0%) | 39 (100%) | 63 (100%) | 0 (0%) | 27 (100%) | 0 (0%) | 158 (100%) | 351 (33.5%) |
| Netherlands | 0 (0%) | 0 (0%) | 0 (0%) | 55 (33.3%) | 0 (0%) | 0 (0%) | 0 (0%) | 0 (0%) | 0 (0%) | 0 (0%) | 55 (5.3%) |
| Spain | 0 (0%) | 0 (0%) | 0 (0%) | 12 (7.3%) | 0 (0%) | 0 (0%) | 0 (0%) | 0 (0%) | 0 (0%) | 0 (0%) | 12 (1.1%) |
| United Kingdom | 0 (0%) | 0 (0%) | 0 (0%) | 98 (59.4%) | 0 (0%) | 0 (0%) | 0 (0%) | 0 (0%) | 0 (0%) | 0 (0%) | 98 (9.4%) |
| China | 0 (0%) | 0 (0%) | 0 (0%) | 0 (0%) | 0 (0%) | 0 (0%) | 40 (100%) | 0 (0%) | 0 (0%) | 0 (0%) | 40 (3.8%) |