Part 1: ggplot practice

This part is a warmup, it should be relatively straightforward ggplot2 practice.

Load data from Frank, Vul, Saxe (2011, Infancy), a study in which we measured infants’ looking to hands in moving scenes. There were infants from 3 months all the way to about two years, and there were two movie conditions (Faces_Medium, in which kids played on a white background, and Faces_Plus, in which the backgrounds were more complex and the people in the videos were both kids and adults). An eye-tracker measured children’s attention to faces. This version of the dataset only gives two conditions and only shows the amount of looking at hands (other variables were measured as well).

library(tidyverse)

## ── Attaching packages ─────────────────────────────────────── tidyverse 1.3.2 ──
## ✔ ggplot2 3.3.6      ✔ purrr   0.3.4 
## ✔ tibble  3.1.8      ✔ dplyr   1.0.10
## ✔ tidyr   1.2.1      ✔ stringr 1.4.0 
## ✔ readr   2.1.2      ✔ forcats 0.5.1 
## ── Conflicts ────────────────────────────────────────── tidyverse_conflicts() ──
## ✖ dplyr::filter() masks stats::filter()
## ✖ dplyr::lag()    masks stats::lag()

fvs <- read_csv("data/FVS2011-hands.csv")

## Rows: 232 Columns: 4
## ── Column specification ────────────────────────────────────────────────────────
## Delimiter: ","
## chr (1): condition
## dbl (3): subid, age, hand.look
## 
## ℹ Use `spec()` to retrieve the full column specification for this data.
## ℹ Specify the column types or set `show_col_types = FALSE` to quiet this message.

First, use ggplot to plot a histogram of the ages of children in the study. NOTE: this is a repeated measures design, so you can’t just take a histogram of every measurement.

fvs_id_age <- fvs |> select(subid, age) |> distinct()
ggplot(fvs_id_age) + geom_histogram(aes(age), binwidth=1) 

Second, make a scatter plot showing hand looking as a function of age and condition. Add appropriate smoothing lines. Take the time to fix the axis labels and make the plot look nice.

ggplot(fvs, aes(x=age, y=hand.look)) + geom_point() + 
  geom_smooth(method = lm) + 
  facet_grid(~condition) + 
  theme_classic()

## `geom_smooth()` using formula 'y ~ x'

What do you conclude from this pattern of data?

relationship between age and hand look seems stronger for the faces_plus condiction rather than the faces_medium condition.

What statistical analyses would you perform here to quantify these differences?

Linear mixed model with age\(\times\)condition interaction predictor

Part 2: Simulation

Let’s start by convincing ourselves that t-tests have the appropriate false positive rate. Run 10,000 t-tests with standard, normally-distributed data from a made up 30-person, single-measurement experiment (the command for sampling from a normal distribution is rnorm).

The goal of these t-tests are to determine, based on 30 observations, whether the underlying distribution (in this case a normal distribution with mean 0 and standard deviation 1) has a mean that is different from 0. In reality, the mean is not different from 0 (we sampled it using rnorm), but sometimes the 30 observations we get in our experiment will suggest that the mean is higher or lower. In this case, we’ll get a “significant” result and incorrectly reject the null hypothesis of mean 0.

What’s the proportion of “significant” results (\(p < .05\)) that you see?

First do this using a for loop.

p <- NULL
for (i in 1:10000){
  dat <- rnorm(30, 0, 1)
  p_i <- t.test(dat)$p.value
  p <- c(p, p_i)
}

ggplot(as.data.frame(p)) + geom_density(aes(x=p)) + geom_vline(xintercept=0.05, linetype='dashed')

sig = ifelse(p<.05, 1, 0)
# the proportion of "significant" results ($p < .05$) 
mean(sig)

## [1] 0.0515

How does this compare to the intended false-positive rate of \(\alpha=0.05\)?

similar, almost same

Ok, that was a bit boring. Let’s try something more interesting - let’s implement a p-value sniffing simulation, in the style of Simons, Nelson, & Simonsohn (2011).

Consider this scenario: you have done an experiment, again with 30 participants (one observation each, just for simplicity). The question is whether the true mean is different from 0. You aren’t going to check the p-value every trial, but let’s say you run 30 - then if the p-value is within the range p < .25 and p > .05, you optionally run 30 more and add those data, then test again. But if the original p value is < .05, you call it a day, and if the original is > .25, you also stop.

First, write a function that implements this sampling regime.

double.sample <- function (p_threshold) {
  dat <- rnorm(30, 0, 1)
  p_i <- t.test(dat)$p.value
  if(p_i>0.05 & p_i<p_threshold){
    dat <- c(dat, rnorm(30, 0, 1))
  }
  p_i <- t.test(dat)$p.value
  return(p_i)
}

Now call this function 10k times and find out what happens.

p <- NULL
for (i in 1:10000){
  p_i <- double.sample(0.25)
  p <- c(p, p_i)
}

ggplot(as.data.frame(p)) + geom_density(aes(x=p)) + geom_vline(xintercept=0.05, linetype='dashed')

sig = ifelse(p<.05, 1, 0)
# the proportion of "significant" results ($p < .05$) 
mean(sig)

## [1] 0.0708

Is there an inflation of false positives? How bad is it?

much larger than 0.05

Now modify this code so that you can investigate this “double the sample” rule in a bit more depth. In the previous question, the researcher doubles the sample only when they think they got “close” to a significant result, i.e. when their not-significant p is less than 0.25. What if the researcher was more optimistic? See what happens in these 3 other scenarios:

• The researcher doubles the sample whenever their pvalue is not significant, but it’s less than 0.5.
• The researcher doubles the sample whenever their pvalue is not significant, but it’s less than 0.75.
• The research doubles their sample whenever they get ANY pvalue that is not significant.

How do these choices affect the false positive rate?

HINT: Try to do this by making the function double.sample take the upper p value as an argument, so that you can pass this through dplyr.

HINT 2: You may need more samples. Find out by looking at how the results change from run to run.

threshold = c(0.5, 0.75, 1.01)
for (thresholdi in threshold){
  for (i in 1:10000){
    p_i <- double.sample(thresholdi)
    p <- c(p, p_i)
  }
  sig <- ifelse(p<.05, 1, 0)
  cat(paste0(thresholdi, '\t'))
  cat(mean(sig))
  cat('\n')
}

## 0.5  0.07755
## 0.75 0.07813333
## 1.01 0.079775

What do you conclude on the basis of this simulation?

false positive rates increased as the threshold increased.

How bad is this kind of data-dependent policy?

will lead to inflated false positive rates