Lab Visualization

1 Damage Zone Analysis - CO-raft

1.1 hIAPP-induced membrane damage in CO-raft (Chain Average)

1.2 hIAPP-induced membrane damage in CO-raft (2 separate chains)

1.3 hIAPP-induced membrane damage in CO-raft (3 replicates - 2 separate chains)

1.3.1 Combined plot for three replicates - Monomer n=1 chain 1

1.3.2 Combined plot for three replicates - Monomer n=1 chain 2

1.3.3 Combined plot for three replicates - Dimer n=2 chain 1

1.3.4 Combined plot for three replicates - Dimer n=2 chain 2

1.3.5 Combined plot for three replicates - Tetramer n=4 chain 1

1.3.6 Combined plot for three replicates - Tetramer n=4 chain 2

2 CO Minimum Distance Spectra

2.1 Monomer

2.1.1 Mindist visualization for Chol, DPP, DLP & Water:

2.1.2 Hydropathy

2.1.3 Plot A: hIAPP monomer on raft surface

2.2 Dinomer

2.2.1 Plot B: Mindist visualization for Chol, DPP, DUP & Water (no chain average):

2.2.2 Mindist visualization for Chol, DPP, DLP & Water (chain average)

2.3 Tetramer

2.3.1 Plot C: hIAPP tetramer on raft surface (no chain average):

2.3.2 Mindist visualization for Chol, DPP, DLP & Water (chain average)

3 CO Minimum Distance Spectra - Hydropathy

3.1 Chain A

3.2 Chain B, C & D