Currate ADNI & BULLET Phantoms
Last Ran: 2022-11-29
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ADNI Phantom
Full dataset
| PRISMA 1 (N=42) |
PRISMA 2 (N=12) |
SKYRA (N=53) |
NUBIC (N=58) |
P-value | |
|---|---|---|---|---|---|
| Year | |||||
| 2018 | 7 (16.7%) | 0 (0%) | 6 (11.3%) | 9 (15.5%) | 0.117 |
| 2019 | 10 (23.8%) | 5 (41.7%) | 16 (30.2%) | 15 (25.9%) | |
| 2020 | 7 (16.7%) | 7 (58.3%) | 10 (18.9%) | 10 (17.2%) | |
| 2021 | 11 (26.2%) | 0 (0%) | 11 (20.8%) | 13 (22.4%) | |
| 2022 | 7 (16.7%) | 0 (0%) | 10 (18.9%) | 11 (19.0%) | |
| SNR | |||||
| Mean (SD) | 112 (4.17) | 109 (2.54) | 140 (14.2) | 112 (2.68) | <0.001 |
| Median [Min, Max] | 112 [105, 119] | 108 [106, 115] | 143 [67.9, 150] | 112 [106, 118] | |
| SNR_manufacturerZ | |||||
| Mean (SD) | -0.0143 (1.21) | -0.825 (0.746) | 0.00943 (1.00) | 0.190 (0.780) | 0.015 |
| Median [Min, Max] | 0.100 [-1.90, 2.30] | -1.10 [-1.70, 0.900] | 0.200 [-5.10, 0.700] | 0.200 [-1.60, 1.70] | |
| SNR_siteZ | |||||
| Mean (SD) | 0.160 (1.03) | -0.542 (0.626) | 0.00943 (1.00) | 0.00517 (1.00) | 0.2 |
| Median [Min, Max] | 0.200 [-1.40, 2.10] | -0.750 [-1.30, 0.900] | 0.200 [-5.10, 0.700] | 0 [-2.30, 2.00] | |
| SNR_ScannerZ | |||||
| Mean (SD) | 0.00476 (1.01) | 0.00833 (0.990) | 0.00943 (1.00) | 0.00517 (1.00) | 1 |
| Median [Min, Max] | 0.100 [-1.50, 1.90] | -0.300 [-1.20, 2.30] | 0.200 [-5.10, 0.700] | 0 [-2.30, 2.00] |
Outlier detection
| Outlier (N=2) |
Within Range (N=163) |
P-value | |
|---|---|---|---|
| ADNI_site_outlier.factor | |||
| Outlier | 2 (100%) | 0 (0%) | <0.001 |
| Within Range | 0 (0%) | 163 (100%) | |
| ADNI_manufacture_outlier.factor | |||
| Outlier | 2 (100%) | 0 (0%) | <0.001 |
| Within Range | 0 (0%) | 163 (100%) | |
| Year | |||
| 2018 | 0 (0%) | 22 (13.5%) | 0.596 |
| 2019 | 1 (50.0%) | 45 (27.6%) | |
| 2020 | 0 (0%) | 34 (20.9%) | |
| 2021 | 0 (0%) | 35 (21.5%) | |
| 2022 | 1 (50.0%) | 27 (16.6%) | |
| SCANNER | |||
| PRISMA 1 | 0 (0%) | 42 (25.8%) | 0.233 |
| PRISMA 2 | 0 (0%) | 12 (7.4%) | |
| SKYRA | 2 (100%) | 51 (31.3%) | |
| NUBIC | 0 (0%) | 58 (35.6%) |
Restricted data
- Data restricted to points with no parameter changes and total number of expected volumes, and no outliers (standardized Z score more than 3SDs from mean).
PRISMA |
SKYRA |
Overall |
||
|---|---|---|---|---|
| Within Range (N=112) |
Within Range (N=51) |
Within Range (N=163) |
P-value | |
| SNR | ||||
| Mean (SD) | 112 (3.44) | 143 (3.55) | 121 (15.0) | <0.001 |
| Median [Min, Max] | 112 [105, 119] | 143 [133, 150] | 114 [105, 150] | |
| SNR_ScannerZ | ||||
| Mean (SD) | 0.00536 (0.994) | 0.200 (0.257) | 0.0663 (0.840) | 0.39 |
| Median [Min, Max] | 0 [-2.30, 2.30] | 0.200 [-0.500, 0.700] | 0.100 [-2.30, 2.30] | |
| SNR_siteZ | ||||
| Mean (SD) | 0.00446 (0.994) | 0.200 (0.257) | 0.0656 (0.840) | 0.387 |
| Median [Min, Max] | -0.100 [-2.30, 2.10] | 0.200 [-0.500, 0.700] | 0.100 [-2.30, 2.10] | |
| SNR_manufacturerZ | ||||
| Mean (SD) | 0.00446 (1.00) | 0.200 (0.257) | 0.0656 (0.845) | 0.392 |
| Median [Min, Max] | 0.100 [-1.90, 2.30] | 0.200 [-0.500, 0.700] | 0.100 [-1.90, 2.30] |
SNR Stability Across Time
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Variation across quarters
Normalized Across Time
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Curate BULLET Phantom -
Full dataset
PRISMA |
SKYRA |
||||
|---|---|---|---|---|---|
| Outlier (N=9) |
Within Range (N=270) |
Outlier (N=3) |
Within Range (N=132) |
P-value | |
| Site | |||||
| Northeastern | 5 (55.6%) | 117 (43.3%) | 0 (0%) | 0 (0%) | <0.001 |
| Pittsburgh | 4 (44.4%) | 153 (56.7%) | 0 (0%) | 0 (0%) | |
| Kansas | 0 (0%) | 0 (0%) | 3 (100%) | 132 (100%) | |
| Year | |||||
| 2018 | 0 (0%) | 110 (40.7%) | 0 (0%) | 53 (40.2%) | <0.001 |
| 2019 | 0 (0%) | 67 (24.8%) | 2 (66.7%) | 23 (17.4%) | |
| 2020 | 8 (88.9%) | 37 (13.7%) | 1 (33.3%) | 20 (15.2%) | |
| 2021 | 1 (11.1%) | 33 (12.2%) | 0 (0%) | 19 (14.4%) | |
| 2022 | 0 (0%) | 23 (8.5%) | 0 (0%) | 17 (12.9%) | |
| SNR | |||||
| Mean (SD) | 39.5 (5.66) | 99.0 (6.45) | 96.4 (60.6) | 101 (3.33) | <0.001 |
| Median [Min, Max] | 38.3 [31.8, 47.2] | 97.0 [86.7, 117] | 61.4 [61.4, 166] | 100 [88.5, 109] | |
| SNR_manufacturerZ | |||||
| Mean (SD) | -4.03 (0.403) | 0.173 (0.457) | -0.533 (6.52) | -0.0803 (0.365) | <0.001 |
| Median [Min, Max] | -4.10 [-4.60, -3.50] | 0 [-0.700, 1.50] | -4.30 [-4.30, 7.00] | -0.100 [-1.40, 0.900] | |
| SNR_siteZ | |||||
| Mean (SD) | -4.02 (0.319) | 0.175 (0.482) | -0.533 (6.52) | -0.0803 (0.365) | <0.001 |
| Median [Min, Max] | -4.00 [-4.50, -3.60] | 0.200 [-1.00, 1.40] | -4.30 [-4.30, 7.00] | -0.100 [-1.40, 0.900] | |
| SNR_scannerZ | |||||
| Mean (SD) | -4.02 (0.387) | 0.170 (0.489) | -0.533 (6.52) | -0.0803 (0.365) | <0.001 |
| Median [Min, Max] | -4.00 [-4.90, -3.60] | 0.200 [-1.10, 1.50] | -4.30 [-4.30, 7.00] | -0.100 [-1.40, 0.900] | |
| SpikeCount.ord.factor | |||||
| Low | 0 (0%) | 260 (96.3%) | 0 (0%) | 130 (98.5%) | <0.001 |
| Med | 0 (0%) | 8 (3.0%) | 0 (0%) | 2 (1.5%) | |
| High | 9 (100%) | 2 (0.7%) | 3 (100%) | 0 (0%) | |
| Kansas (N=135) |
Northeastern (N=122) |
Pittsburgh (N=157) |
P-value | |
|---|---|---|---|---|
| SpikeCount.ord.factor | ||||
| Low | 130 (96.3%) | 114 (93.4%) | 146 (93.0%) | 0.776 |
| Med | 2 (1.5%) | 3 (2.5%) | 5 (3.2%) | |
| High | 3 (2.2%) | 5 (4.1%) | 6 (3.8%) |
Exploratory Factor Analysis (PCA)
NO-SpikeCount
Dimension contribution across time-
Principal Componants across time
