Two_brain_sample_analysis
LC/Qiu lab
2022-09-12
Initialize relevant libraries
Import libaries for analysis
# setwd("D:/Bioinformatics Projects/sc_exp2")
library(Seurat)
library(dplyr)
library(cowplot)
library(ggplot2)
library(rstatix)
library(SingleCellExperiment)
library(ComplexHeatmap)
library(RColorBrewer)
library(circlize)
library(patchwork)Import two samples
To minimize change of coding, keep the existing variable names as much as possile. Copy the slim_counts/ files to the m10 and m11 folder under ‘./slim_counts’
Quality Control
Quality assessment before filtering
Joint filtering effects:
Quality assessment after filtering
Selecting Data Subset
Filter data based on these criteria: nFeature_RNA < 7500& nFeature_RNA>75 & nCount_RNA > 1000 and then, added the filtering criteria of “percent.mt < 20” After subseting, only keeping those genes expressed in more than 20 cells
The dimension of pooled data is:16504, 13551
Reassess quality metrics
Quality metrics after filtered counts
Apply sctransform normalization
This steps can replace NormalizeData(),
ScaleData(), and FindVariableFeatures(). The
results of sctransform are stored in the “SCT” assay. It is assumed to
reveals sharper biological distinctions compared to the standard Seurat
workflow.
Since it is a normalization step, we have to do
separately for two different samples (that’s why split seurat objects
here), then only integrate the sample expression data in the next step,
integration analysis, to remove batch effect.
Integration of two samples
Select the most variable features to use for integration, we
will use 3000 features and IntegratData
Clustering
Run the standard workflow for linear and non-linear reduction, visualization and clustering
We use a resolution vector c(0.05, 0.5) for cluster identification, which seems appropriate for this sample size ~13K cells
Clustering quality control
This step gives us some idea about how is the distribution of the number of genes, number of UMIs, and percentage of mitochondrial genes in each cluster. Normally, we expect to see similar distribution of no. of genes (nFeature_RNA) and no. of UMIs (nCount_RNA).
As for the percent.mt (percentage of mitochondrial genes per cell), it can be a reference to check if those high intensity clusters might be having poor quality cells (if so, we can try to remove in the next step or adjust the metrics in the previous filtering step) or it might be due to the differences biologically.
Determine metrics to plot present in seurat_integrated@meta.data
NOTE from SQ: for certain feature if not found in ‘integrated’ assay (may only have 2000 high variable features), you need to switch to “RNA” or “SCT” assay using DefaultAssay(seurat_integrated) <- “RNA”
Find all markers in two samples for cell type identification
Write all gene markers to a .csv file on local drive
Plotting top markers for each cluster
setting up plotting parameters
##Violin plot for selected gene markers For example, genes in the MAPK
pathway
Define genes of interest and do heatmaps
Find markers for specific cluster in two samples for cell type identification
Identifying cell type
Option 1: SingleR package with built-in reference
I use a collection of mouse bulk RNA-seq data sets obtained from celldex package (Benayoun et al. 2019). A variety of cell types are available, mostly from blood but also covering several other tissues. This identifies marker genes from the reference and uses them to compute assignment scores (based on the Spearman correlation across markers) for each cell in the test dataset against each label in the reference. The label with the highest score is the assigned to the test cell, possibly with further fine-tuning to resolve closely related labels.
This reference consists of a collection of mouse bulk RNA-seq data sets downloaded from the gene expression omnibus Benayoun et al. 2019. A variety of cell types are available, again mostly from blood but also covering several other tissues.
Option 2: manual annotation
####Plotting Astrocyte Markers
####Plotting Microglia Markers
####Plotting Endothelial Markers
####Plotting Oligodendrocyte Markers
####Plotting Glutamatergic Neuron Markers
####Plotting Gabaergic Neuron Markers
####Plotting Oligodendrocyte Precursor Markers
Rename cluster based on the SingleR results and manual annotation
Option 3: manual annotation
Refer to Tasic et al, Nature 2018, [marker list] https://github.com/AllenInstitute/tasic2018analysis/blob/master/RNA-seq%20Analysis/markers.R
## Differential expression Analysis for groups Now we do a DEG
analysis for all genes between the two groups
## [[1]]
## p_val avg_log2FC pct.1 pct.2 p_val_adj comparison
## Cnp 0.000000e+00 0.4657241 0.122 0.093 0.000000e+00 CTL_MUT
## Ptgds 0.000000e+00 -4.5066449 0.108 0.056 0.000000e+00 CTL_MUT
## Pvalb 0.000000e+00 -2.9104214 0.140 0.010 0.000000e+00 CTL_MUT
## Cox6a2 0.000000e+00 -1.5277921 0.104 0.008 0.000000e+00 CTL_MUT
## Adamts4 0.000000e+00 -2.7657613 0.104 0.013 0.000000e+00 CTL_MUT
## Nfe2l2 0.000000e+00 -2.5646689 0.101 0.039 0.000000e+00 CTL_MUT
## Vcam1 0.000000e+00 -1.9861395 0.101 0.024 0.000000e+00 CTL_MUT
## Slc6a1 0.000000e+00 -2.4988197 0.126 0.063 0.000000e+00 CTL_MUT
## C130073E24Rik 0.000000e+00 -5.0513026 0.111 0.034 0.000000e+00 CTL_MUT
## Elovl1 0.000000e+00 -3.4247739 0.124 0.026 0.000000e+00 CTL_MUT
## Erbb4 0.000000e+00 -1.4261140 0.129 0.033 0.000000e+00 CTL_MUT
## Mgl2 0.000000e+00 -3.8588697 0.026 0.100 0.000000e+00 CTL_MUT
## Rapgef3 0.000000e+00 -0.3032082 0.125 0.038 0.000000e+00 CTL_MUT
## Rmst 0.000000e+00 -2.8294385 0.125 0.065 0.000000e+00 CTL_MUT
## Appl2 0.000000e+00 0.2530487 0.116 0.048 0.000000e+00 CTL_MUT
## Tspan15 0.000000e+00 -5.6936568 0.101 0.021 0.000000e+00 CTL_MUT
## Plekhg3 0.000000e+00 -2.5254028 0.115 0.011 0.000000e+00 CTL_MUT
## Prr5l 0.000000e+00 -2.2166550 0.107 0.013 0.000000e+00 CTL_MUT
## Oprk1 0.000000e+00 -3.0378988 0.116 0.011 0.000000e+00 CTL_MUT
## Psat1 0.000000e+00 -3.2136211 0.122 0.066 0.000000e+00 CTL_MUT
## Oaf 0.000000e+00 -2.9014778 0.104 0.023 0.000000e+00 CTL_MUT
## Col15a1 0.000000e+00 -4.3554791 0.109 0.003 0.000000e+00 CTL_MUT
## Pim1 0.000000e+00 -4.3904571 0.122 0.021 0.000000e+00 CTL_MUT
## Kif20b 0.000000e+00 -2.3161840 0.108 0.004 0.000000e+00 CTL_MUT
## Unc5b 0.000000e+00 -1.9368243 0.134 0.011 0.000000e+00 CTL_MUT
## Notch2 0.000000e+00 -1.8857925 0.126 0.011 0.000000e+00 CTL_MUT
## Sned1 0.000000e+00 -3.6740086 0.117 0.006 0.000000e+00 CTL_MUT
## Nr2e1 0.000000e+00 -1.8958098 0.119 0.011 0.000000e+00 CTL_MUT
## Smoc1 0.000000e+00 -1.8310048 0.112 0.014 0.000000e+00 CTL_MUT
## Stard13 0.000000e+00 -2.8803653 0.117 0.011 0.000000e+00 CTL_MUT
## Sox1 0.000000e+00 -2.6148187 0.100 0.018 0.000000e+00 CTL_MUT
## Ptprm 0.000000e+00 -2.8391016 0.151 0.028 0.000000e+00 CTL_MUT
## Gm20383 0.000000e+00 -5.2307329 0.023 0.184 0.000000e+00 CTL_MUT
## Gm15893 0.000000e+00 -4.9645606 0.112 0.003 0.000000e+00 CTL_MUT
## Stk17b 0.000000e+00 -3.3660726 0.121 0.018 0.000000e+00 CTL_MUT
## Defb42 0.000000e+00 -3.4361972 0.106 0.002 0.000000e+00 CTL_MUT
## Adamts9 0.000000e+00 -4.2399376 0.106 0.006 0.000000e+00 CTL_MUT
## B430010I23Rik 0.000000e+00 -4.1209470 0.134 0.015 0.000000e+00 CTL_MUT
## Ptges 0.000000e+00 -4.0161294 0.105 0.006 0.000000e+00 CTL_MUT
## Fmo5 0.000000e+00 -3.2352746 0.134 0.006 0.000000e+00 CTL_MUT
## Fzd7 0.000000e+00 -4.7541753 0.126 0.003 0.000000e+00 CTL_MUT
## Acsf2 0.000000e+00 -3.6582240 0.116 0.004 0.000000e+00 CTL_MUT
## Papss2 0.000000e+00 -2.6828353 0.138 0.005 0.000000e+00 CTL_MUT
## Ston2 0.000000e+00 -3.5696634 0.118 0.015 0.000000e+00 CTL_MUT
## Dnase2a 0.000000e+00 -3.6960049 0.125 0.008 0.000000e+00 CTL_MUT
## Agmo 0.000000e+00 -3.7506871 0.121 0.005 0.000000e+00 CTL_MUT
## Srebf1 0.000000e+00 -3.2678006 0.121 0.015 0.000000e+00 CTL_MUT
## Tubb6 0.000000e+00 -3.5369929 0.101 0.005 0.000000e+00 CTL_MUT
## Wnt7a 0.000000e+00 -3.2517192 0.112 0.013 0.000000e+00 CTL_MUT
## Col11a2 0.000000e+00 -2.4475638 0.102 0.009 0.000000e+00 CTL_MUT
## Nkx2-2 0.000000e+00 -2.9673521 0.104 0.004 0.000000e+00 CTL_MUT
## Pctp 0.000000e+00 -4.2094020 0.117 0.002 0.000000e+00 CTL_MUT
## Tfeb 0.000000e+00 -2.2565017 0.128 0.010 0.000000e+00 CTL_MUT
## Gm4221 0.000000e+00 -4.9987233 0.136 0.005 0.000000e+00 CTL_MUT
## Prdm5 0.000000e+00 -3.6660911 0.142 0.007 0.000000e+00 CTL_MUT
## Rhcg 0.000000e+00 -4.9187137 0.114 0.005 0.000000e+00 CTL_MUT
## Hspb2 0.000000e+00 -1.7906671 0.107 0.006 0.000000e+00 CTL_MUT
## Arl5c 0.000000e+00 -5.1737521 0.124 0.006 0.000000e+00 CTL_MUT
## Gm33594 0.000000e+00 -2.8893757 0.038 0.337 0.000000e+00 CTL_MUT
## Gm4890 0.000000e+00 -4.1369103 0.113 0.002 0.000000e+00 CTL_MUT
## Rbpms2 0.000000e+00 -4.5889757 0.139 0.003 0.000000e+00 CTL_MUT
## Efna1 0.000000e+00 -5.3434692 0.136 0.005 0.000000e+00 CTL_MUT
## 4933415A04Rik 0.000000e+00 -4.8460176 0.122 0.003 0.000000e+00 CTL_MUT
## 4831440D22Rik 0.000000e+00 -4.7346513 0.144 0.003 0.000000e+00 CTL_MUT
## Gm26737 0.000000e+00 -3.2602152 0.110 0.001 0.000000e+00 CTL_MUT
## Fzd5 0.000000e+00 -4.3916017 0.139 0.002 0.000000e+00 CTL_MUT
## Gm26512 0.000000e+00 -4.2107946 0.124 0.004 0.000000e+00 CTL_MUT
## Gm20186 0.000000e+00 -6.2168459 0.166 0.006 0.000000e+00 CTL_MUT
## Pdlim3 0.000000e+00 -2.7723240 0.117 0.003 0.000000e+00 CTL_MUT
## Gask1a 0.000000e+00 -3.8244693 0.104 0.004 0.000000e+00 CTL_MUT
## Cyp39a1 0.000000e+00 -5.2242283 0.120 0.004 0.000000e+00 CTL_MUT
## Six5 0.000000e+00 -5.4952733 0.114 0.002 0.000000e+00 CTL_MUT
## Lrrc32 0.000000e+00 -6.2235876 0.127 0.005 0.000000e+00 CTL_MUT
## Mob3b 0.000000e+00 -4.2768229 0.141 0.009 0.000000e+00 CTL_MUT
## Gm36608 0.000000e+00 -3.8938830 0.101 0.001 0.000000e+00 CTL_MUT
## 1190005I06Rik 0.000000e+00 -2.4939323 0.145 0.043 0.000000e+00 CTL_MUT
## Rad51 0.000000e+00 -4.5645087 0.116 0.003 0.000000e+00 CTL_MUT
## Mmp25 0.000000e+00 -2.7499584 0.135 0.001 0.000000e+00 CTL_MUT
## Slfn9 0.000000e+00 -3.1360333 0.112 0.002 0.000000e+00 CTL_MUT
## Rbm46 0.000000e+00 -4.0441405 0.101 0.004 0.000000e+00 CTL_MUT
## Tpbgl 0.000000e+00 -4.3157160 0.123 0.008 0.000000e+00 CTL_MUT
## Dock5 0.000000e+00 -3.4212252 0.110 0.005 0.000000e+00 CTL_MUT
## Cryzl2 0.000000e+00 -5.0130977 0.113 0.006 0.000000e+00 CTL_MUT
## Il1r2 0.000000e+00 -1.5983610 0.100 0.001 0.000000e+00 CTL_MUT
## Dlx6 0.000000e+00 -3.2722646 0.100 0.011 0.000000e+00 CTL_MUT
## E030044B06Rik 0.000000e+00 -5.4337805 0.128 0.002 0.000000e+00 CTL_MUT
## Pla2g3 0.000000e+00 -5.1422738 0.111 0.005 0.000000e+00 CTL_MUT
## Ptpn22 0.000000e+00 -4.1280675 0.130 0.002 0.000000e+00 CTL_MUT
## A330093E20Rik 0.000000e+00 -4.3482019 0.135 0.004 0.000000e+00 CTL_MUT
## Zfp503 0.000000e+00 -5.7340413 0.140 0.004 0.000000e+00 CTL_MUT
## Irak4 0.000000e+00 -3.7855590 0.116 0.003 0.000000e+00 CTL_MUT
## Serpind1 0.000000e+00 -5.2532746 0.104 0.003 0.000000e+00 CTL_MUT
## Rasgrp4 0.000000e+00 -3.8084031 0.116 0.003 0.000000e+00 CTL_MUT
## Pygl 0.000000e+00 -4.8956050 0.118 0.005 0.000000e+00 CTL_MUT
## Als2cl 0.000000e+00 -3.5590476 0.138 0.005 0.000000e+00 CTL_MUT
## Hsd3b7 0.000000e+00 -5.8015224 0.107 0.008 0.000000e+00 CTL_MUT
## Olfr57 0.000000e+00 -3.3640323 0.122 0.001 0.000000e+00 CTL_MUT
## S1pr4 0.000000e+00 -3.5004924 0.102 0.002 0.000000e+00 CTL_MUT
## Cyp2j6 2.144154e-307 -0.8194195 0.128 0.034 6.432462e-304 CTL_MUT
## Prss41 3.387489e-307 -5.1127384 0.144 0.002 1.016247e-303 CTL_MUT
## Pllp 1.363623e-305 -3.5323775 0.112 0.040 4.090870e-302 CTL_MUT
## Acaa2 1.038183e-304 0.6374996 0.107 0.039 3.114549e-301 CTL_MUT
## Gbp2 2.143073e-304 -1.9401894 0.102 0.004 6.429219e-301 CTL_MUT
## Dapp1 8.295279e-304 -2.5518077 0.111 0.009 2.488584e-300 CTL_MUT
## Slc26a1 2.110170e-302 -4.8950766 0.133 0.003 6.330509e-299 CTL_MUT
## Wipf1 2.656052e-302 -0.9233029 0.105 0.015 7.968157e-299 CTL_MUT
## Fgfrl1 6.504795e-302 -3.8138119 0.115 0.005 1.951439e-298 CTL_MUT
## Daam2 1.214394e-301 -1.1873844 0.104 0.040 3.643183e-298 CTL_MUT
## Cyp4f17 4.693131e-300 -4.6062253 0.114 0.011 1.407939e-296 CTL_MUT
## Islr 1.367966e-299 -3.6927696 0.124 0.012 4.103899e-296 CTL_MUT
## Kcne1l 2.283343e-299 -3.1232024 0.101 0.004 6.850028e-296 CTL_MUT
## Bmpr1b 4.947201e-299 -1.1784404 0.124 0.036 1.484160e-295 CTL_MUT
## Heph 3.404590e-298 -4.1942723 0.142 0.003 1.021377e-294 CTL_MUT
## Nfkbid 2.155836e-297 -4.1190004 0.107 0.014 6.467508e-294 CTL_MUT
## F5 1.992137e-296 -3.1434982 0.107 0.001 5.976410e-293 CTL_MUT
## AW047730 5.096200e-295 -2.8851075 0.105 0.044 1.528860e-291 CTL_MUT
## Csf1 3.165269e-294 -4.8039135 0.122 0.025 9.495806e-291 CTL_MUT
## Npb 1.131654e-293 -3.7118051 0.125 0.003 3.394962e-290 CTL_MUT
## Hist1h2bm 5.286542e-292 -4.7294432 0.112 0.001 1.585963e-288 CTL_MUT
## Mid1ip1 2.699463e-291 -0.4396231 0.149 0.072 8.098389e-288 CTL_MUT
## Slc25a45 1.504366e-290 -4.3377854 0.125 0.003 4.513097e-287 CTL_MUT
## Pygm 2.478232e-289 -3.8673356 0.110 0.019 7.434695e-286 CTL_MUT
## Cenpa 3.195186e-289 -0.6738844 0.147 0.016 9.585559e-286 CTL_MUT
## Gja1 5.162614e-289 -2.2455065 0.085 0.100 1.548784e-285 CTL_MUT
## Sept10 2.501989e-287 -2.2225234 0.137 0.011 7.505968e-284 CTL_MUT
## Hs3st3a1 3.842548e-287 -3.2949896 0.106 0.005 1.152764e-283 CTL_MUT
## Slc14a1 5.362922e-287 -4.7920092 0.108 0.003 1.608877e-283 CTL_MUT
## Stard6 6.214968e-287 -4.7329998 0.154 0.002 1.864490e-283 CTL_MUT
## Ly6d 3.023465e-286 -5.0657442 0.121 0.028 9.070395e-283 CTL_MUT
## Eya2 3.591930e-286 -4.6073335 0.114 0.004 1.077579e-282 CTL_MUT
## Eln 5.819028e-286 -5.3743960 0.131 0.006 1.745708e-282 CTL_MUT
## Btbd11 7.074535e-286 -1.4380104 0.129 0.011 2.122361e-282 CTL_MUT
## Id4 2.966939e-285 -1.9302843 0.132 0.078 8.900818e-282 CTL_MUT
## Hadh 1.848951e-284 -2.6382800 0.103 0.035 5.546854e-281 CTL_MUT
## 3010003L21Rik 4.487472e-284 -3.4686245 0.133 0.003 1.346242e-280 CTL_MUT
## Tnfsf13 8.097280e-284 -4.4898059 0.101 0.004 2.429184e-280 CTL_MUT
## Fgfr2 1.063570e-283 -3.2752083 0.118 0.030 3.190711e-280 CTL_MUT
## Hmox1 1.698390e-283 -5.7584526 0.150 0.010 5.095169e-280 CTL_MUT
## 3110082J24Rik 2.785881e-283 -3.6928702 0.109 0.007 8.357644e-280 CTL_MUT
## Slc1a3 4.014631e-283 -0.8838471 0.111 0.171 1.204389e-279 CTL_MUT
## Gm13629 6.966294e-281 -2.4993758 0.121 0.026 2.089888e-277 CTL_MUT
## Scml4 1.492138e-280 -7.2356263 0.131 0.004 4.476415e-277 CTL_MUT
## Kif14 2.520887e-280 -3.7221937 0.147 0.001 7.562662e-277 CTL_MUT
## Il18 4.635040e-280 -1.6412646 0.118 0.053 1.390512e-276 CTL_MUT
## Eogt 5.057024e-280 -4.0928147 0.148 0.015 1.517107e-276 CTL_MUT
## Fmo1 9.313776e-279 -3.0673654 0.107 0.012 2.794133e-275 CTL_MUT
## D7Ertd443e 1.792122e-278 -6.1686173 0.118 0.007 5.376366e-275 CTL_MUT
## Magt1 1.983953e-278 -0.5595908 0.159 0.039 5.951860e-275 CTL_MUT
## Sh3bgr 3.197998e-278 -4.0136602 0.120 0.003 9.593993e-275 CTL_MUT
## Nedd1 5.022816e-278 -4.3702373 0.142 0.006 1.506845e-274 CTL_MUT
## Cnmd 7.065950e-278 -5.2668602 0.139 0.002 2.119785e-274 CTL_MUT
## Nfkbiz 2.520634e-277 -3.5664606 0.108 0.032 7.561903e-274 CTL_MUT
## Car2 4.701798e-277 -1.9134095 0.128 0.080 1.410539e-273 CTL_MUT
## Cd163 2.851607e-276 -3.8575962 0.131 0.043 8.554821e-273 CTL_MUT
## Lrig3 1.296696e-275 -3.9832289 0.144 0.004 3.890088e-272 CTL_MUT
## Tifa 5.300014e-275 -3.8739285 0.108 0.012 1.590004e-271 CTL_MUT
## Ddr1 1.441856e-274 -4.5208461 0.179 0.044 4.325568e-271 CTL_MUT
## Dmrtb1 6.276371e-274 -5.9916429 0.119 0.004 1.882911e-270 CTL_MUT
## Clmn 2.259874e-273 -3.3271022 0.191 0.075 6.779623e-270 CTL_MUT
## Car5b 1.038342e-272 -4.9462774 0.173 0.004 3.115026e-269 CTL_MUT
## Cd63 1.389102e-271 -2.4160779 0.164 0.148 4.167305e-268 CTL_MUT
## Parp4 1.479708e-270 -4.3341168 0.130 0.007 4.439123e-267 CTL_MUT
## Sst 2.667236e-270 -0.9226001 0.164 0.100 8.001708e-267 CTL_MUT
## Glipr2 3.374772e-270 -3.6817917 0.130 0.006 1.012432e-266 CTL_MUT
## Cers2 1.113818e-269 -3.2691097 0.116 0.029 3.341455e-266 CTL_MUT
## S100a16 2.134141e-268 -2.6637907 0.143 0.099 6.402423e-265 CTL_MUT
## Phyhd1 3.090840e-268 -5.1321234 0.109 0.013 9.272520e-265 CTL_MUT
## Eya1 4.701747e-268 -3.4840981 0.152 0.015 1.410524e-264 CTL_MUT
## Gm44265 7.714133e-268 -4.1410872 0.139 0.002 2.314240e-264 CTL_MUT
## Kif15 7.767675e-268 -3.6471939 0.170 0.003 2.330302e-264 CTL_MUT
## Vwa5a 9.212112e-268 -4.6819403 0.146 0.012 2.763633e-264 CTL_MUT
## Htra1 3.861949e-267 -1.4489613 0.116 0.127 1.158585e-263 CTL_MUT
## Plekhh1 8.906775e-265 -1.4432377 0.121 0.012 2.672033e-261 CTL_MUT
## Hopx 1.295579e-264 -4.4633503 0.119 0.020 3.886736e-261 CTL_MUT
## 9530026P05Rik 1.301056e-264 -3.5585612 0.117 0.003 3.903167e-261 CTL_MUT
## Cplx3 3.647703e-264 -1.1177550 0.106 0.017 1.094311e-260 CTL_MUT
## Phactr4 1.158663e-263 -2.9914155 0.132 0.030 3.475988e-260 CTL_MUT
## Arhgef26 2.497484e-263 -2.1029545 0.113 0.035 7.492453e-260 CTL_MUT
## Rnf122 1.036940e-262 -4.6458028 0.132 0.010 3.110819e-259 CTL_MUT
## Ppara 2.322318e-262 -3.7016856 0.112 0.005 6.966955e-259 CTL_MUT
## Mgst1 5.747387e-262 -3.2494104 0.102 0.009 1.724216e-258 CTL_MUT
## Col9a3 1.116194e-261 -4.6862612 0.113 0.022 3.348583e-258 CTL_MUT
## Fmo2 1.293311e-261 -3.7579739 0.140 0.001 3.879934e-258 CTL_MUT
## Echdc3 1.373875e-261 -6.0559117 0.103 0.011 4.121626e-258 CTL_MUT
## Gbp5 2.133895e-261 -2.6178773 0.118 0.004 6.401685e-258 CTL_MUT
## Itpripl1 5.524298e-261 -2.1948522 0.111 0.004 1.657289e-257 CTL_MUT
## Pak4 6.386735e-261 -3.5734960 0.136 0.015 1.916020e-257 CTL_MUT
## Cecr2 6.881553e-261 -3.3028722 0.120 0.010 2.064466e-257 CTL_MUT
## Sqor 8.521549e-261 -4.2354698 0.162 0.005 2.556465e-257 CTL_MUT
## Agt 9.459408e-259 -5.7840185 0.110 0.013 2.837822e-255 CTL_MUT
## Trim12c 1.172331e-258 -3.7190132 0.105 0.004 3.516992e-255 CTL_MUT
## Mt2 3.897824e-258 -1.4164263 0.113 0.102 1.169347e-254 CTL_MUT
## Lpar6 3.407072e-257 -3.4788680 0.152 0.012 1.022122e-253 CTL_MUT
## Slc15a2 8.039544e-257 -1.6603452 0.113 0.024 2.411863e-253 CTL_MUT
## Emp1 1.468880e-256 -4.0959253 0.120 0.003 4.406641e-253 CTL_MUT
## Rexo5 1.516794e-255 -4.5883005 0.136 0.002 4.550381e-252 CTL_MUT
## Eps8l2 9.403194e-255 -4.4906619 0.102 0.004 2.820958e-251 CTL_MUT
## Ripk1 4.768372e-254 -3.9760274 0.177 0.020 1.430512e-250 CTL_MUT
## AI849053 1.089994e-253 -4.7010976 0.151 0.005 3.269983e-250 CTL_MUT
## Mia 2.389820e-253 -3.6715099 0.133 0.004 7.169461e-250 CTL_MUT
## Tmbim1 4.646519e-253 -2.8125739 0.131 0.031 1.393956e-249 CTL_MUT
## Gem 6.453893e-253 -2.5928807 0.133 0.011 1.936168e-249 CTL_MUT
## Prss56 6.562232e-253 -5.1702119 0.108 0.006 1.968669e-249 CTL_MUT
## Dqx1 1.012020e-252 -4.4931200 0.128 0.035 3.036060e-249 CTL_MUT
## Fxyd1 3.040012e-252 -1.4851602 0.172 0.088 9.120037e-249 CTL_MUT
## Igfbp2 2.148561e-251 -4.1903835 0.125 0.050 6.445683e-248 CTL_MUT
## Prex2 4.464002e-251 -1.6786569 0.106 0.062 1.339201e-247 CTL_MUT
## Gsap 1.047918e-250 0.8001593 0.131 0.008 3.143754e-247 CTL_MUT
## Drd2 1.186821e-250 -5.9517595 0.149 0.001 3.560462e-247 CTL_MUT
## Cebpd 2.237045e-250 -2.1788387 0.126 0.026 6.711135e-247 CTL_MUT
## Tfcp2l1 8.760541e-250 -2.1085161 0.115 0.006 2.628162e-246 CTL_MUT
## Pde3b 1.449332e-248 -4.8464017 0.150 0.019 4.347995e-245 CTL_MUT
## Cenpf 9.955727e-248 -2.5155809 0.129 0.008 2.986718e-244 CTL_MUT
## Lrig1 2.570734e-247 -7.3607040 0.174 0.013 7.712203e-244 CTL_MUT
## Lrp5 3.176701e-247 -3.0327990 0.125 0.002 9.530104e-244 CTL_MUT
## Fam111a 1.036954e-246 -6.3299748 0.106 0.012 3.110861e-243 CTL_MUT
## Map3k8 1.434082e-246 -3.4712607 0.165 0.008 4.302246e-243 CTL_MUT
## Nat8f1 2.962036e-246 -1.3830993 0.152 0.065 8.886107e-243 CTL_MUT
## Slc12a4 3.524041e-246 -2.7917822 0.130 0.017 1.057212e-242 CTL_MUT
## Galnt15 1.277538e-245 -4.3228732 0.138 0.005 3.832615e-242 CTL_MUT
## Ccnb1 2.482633e-245 -1.1900715 0.183 0.013 7.447899e-242 CTL_MUT
## Acss2 7.407779e-245 -4.5161026 0.183 0.067 2.222334e-241 CTL_MUT
## Dok1 8.811569e-245 -4.2140929 0.121 0.004 2.643471e-241 CTL_MUT
## Adgra2 9.017338e-245 -3.5343229 0.136 0.007 2.705201e-241 CTL_MUT
## Moxd1 3.846699e-244 -4.8390971 0.109 0.004 1.154010e-240 CTL_MUT
## Sspn 3.989531e-244 -3.0029481 0.116 0.012 1.196859e-240 CTL_MUT
## Gm38348 5.676547e-243 -3.1730121 0.109 0.013 1.702964e-239 CTL_MUT
## Stil 8.211026e-243 -3.8447206 0.144 0.002 2.463308e-239 CTL_MUT
## Malat1 2.977006e-242 -5.7708074 0.564 0.349 8.931019e-239 CTL_MUT
## Tbx18 1.561822e-241 -3.2757638 0.107 0.002 4.685467e-238 CTL_MUT
## Plaat3 2.721380e-241 -3.0513705 0.110 0.027 8.164140e-238 CTL_MUT
## Sox2ot 4.221359e-241 -1.8178926 0.140 0.084 1.266408e-237 CTL_MUT
## Tcn2 1.413481e-240 -0.5975832 0.125 0.031 4.240444e-237 CTL_MUT
## Ttn 1.519126e-240 -3.9478548 0.155 0.005 4.557379e-237 CTL_MUT
## Sema3d 3.953808e-240 -4.2558835 0.117 0.010 1.186143e-236 CTL_MUT
## Hgf 5.372501e-240 -3.3070155 0.121 0.020 1.611750e-236 CTL_MUT
## S1pr5 9.815440e-240 -3.2086395 0.122 0.011 2.944632e-236 CTL_MUT
## Il6ra 4.086539e-239 -4.0694143 0.101 0.009 1.225962e-235 CTL_MUT
## Spidr 1.059765e-238 -3.8017593 0.145 0.005 3.179294e-235 CTL_MUT
## Gm14964 5.133976e-238 -2.5778937 0.131 0.013 1.540193e-234 CTL_MUT
## Notum 1.568875e-237 -2.6453717 0.121 0.001 4.706626e-234 CTL_MUT
## Plscr2 2.718565e-237 -3.2720082 0.130 0.001 8.155695e-234 CTL_MUT
## Cpne2 2.057716e-236 0.6263577 0.128 0.045 6.173147e-233 CTL_MUT
## Bche 2.626217e-236 -3.6878875 0.102 0.003 7.878651e-233 CTL_MUT
## Dock10 1.050120e-235 -3.9994300 0.117 0.035 3.150360e-232 CTL_MUT
## Gm28884 1.369363e-235 -3.1050416 0.157 0.002 4.108089e-232 CTL_MUT
## Ccn2 3.942926e-235 -4.2041779 0.115 0.020 1.182878e-231 CTL_MUT
## Nfatc1 8.823930e-235 -1.8412627 0.122 0.008 2.647179e-231 CTL_MUT
## Car8 1.523964e-234 -1.2958292 0.116 0.011 4.571891e-231 CTL_MUT
## Gm40578 2.066961e-234 -5.0996291 0.117 0.003 6.200884e-231 CTL_MUT
## Zfp521 8.621134e-234 -3.7174089 0.170 0.006 2.586340e-230 CTL_MUT
## Gm32849 5.578398e-233 -5.2522064 0.166 0.006 1.673519e-229 CTL_MUT
## Nxph4 2.506241e-232 -3.5932802 0.107 0.007 7.518724e-229 CTL_MUT
## Synpo2 3.548035e-231 -4.0280538 0.124 0.005 1.064410e-227 CTL_MUT
## Lgals3bp 3.704151e-231 -2.4636352 0.104 0.015 1.111245e-227 CTL_MUT
## Gm8369 4.120414e-231 -3.7604579 0.160 0.003 1.236124e-227 CTL_MUT
## Garem2 4.664156e-231 -4.4773531 0.141 0.005 1.399247e-227 CTL_MUT
## Acacb 4.168420e-230 -2.4804209 0.133 0.004 1.250526e-226 CTL_MUT
## Pald1 6.141885e-230 -4.4824307 0.159 0.005 1.842566e-226 CTL_MUT
## S100b 3.961381e-229 -1.9155963 0.165 0.150 1.188414e-225 CTL_MUT
## Ptpn6 5.577606e-229 -2.5564116 0.112 0.006 1.673282e-225 CTL_MUT
## Timp4 3.806172e-228 -0.5548988 0.180 0.085 1.141852e-224 CTL_MUT
## Dlk1 1.383732e-227 -4.0773893 0.117 0.002 4.151195e-224 CTL_MUT
## Acads 3.896943e-227 -1.5373963 0.175 0.017 1.169083e-223 CTL_MUT
## Haus4 4.716218e-227 -5.7911721 0.142 0.006 1.414866e-223 CTL_MUT
## Col4a3 5.319095e-227 -3.6617452 0.154 0.001 1.595729e-223 CTL_MUT
## 5530401A14Rik 5.378925e-227 -4.4237802 0.178 0.002 1.613677e-223 CTL_MUT
## Plekhf1 5.688580e-227 -4.9190976 0.122 0.006 1.706574e-223 CTL_MUT
## Akain1 1.263834e-226 -3.3203624 0.132 0.016 3.791502e-223 CTL_MUT
## Npas3 1.691548e-226 -3.3709521 0.106 0.039 5.074645e-223 CTL_MUT
## Plin3 1.819572e-226 0.4399547 0.118 0.021 5.458717e-223 CTL_MUT
## Steap3 1.077431e-225 -2.6173401 0.146 0.007 3.232293e-222 CTL_MUT
## Galntl6 2.333876e-225 -3.3656097 0.140 0.031 7.001628e-222 CTL_MUT
## Crhbp 5.226985e-225 -4.0584888 0.143 0.018 1.568096e-221 CTL_MUT
## Fxyd5 1.013651e-224 -1.2500141 0.152 0.030 3.040953e-221 CTL_MUT
## A530084C06Rik 1.157127e-224 -2.1476848 0.100 0.002 3.471381e-221 CTL_MUT
## 6720489N17Rik 1.957566e-224 -4.5353273 0.135 0.003 5.872697e-221 CTL_MUT
## Il4ra 2.590756e-224 -4.9143736 0.178 0.008 7.772267e-221 CTL_MUT
## Gm10635 5.747988e-224 -3.6827249 0.135 0.004 1.724397e-220 CTL_MUT
## Dock11 6.129787e-224 -3.3180924 0.175 0.009 1.838936e-220 CTL_MUT
## Lgals3 1.026494e-223 -3.7005817 0.140 0.001 3.079481e-220 CTL_MUT
## Ecel1 1.584523e-223 -4.2744547 0.143 0.005 4.753570e-220 CTL_MUT
## 2810403D21Rik 1.877401e-222 -3.0329475 0.190 0.014 5.632203e-219 CTL_MUT
## Aim2 1.101651e-221 -4.2005626 0.101 0.007 3.304952e-218 CTL_MUT
## Fam107a 6.944437e-221 -1.1096893 0.105 0.068 2.083331e-217 CTL_MUT
## Tal1 9.970806e-221 -3.4767202 0.110 0.004 2.991242e-217 CTL_MUT
## Sh3tc1 1.088009e-220 -3.2395316 0.100 0.016 3.264026e-217 CTL_MUT
## Nxph1 1.528648e-220 -3.4890513 0.122 0.062 4.585945e-217 CTL_MUT
## Gm49708 2.072045e-220 -3.4474224 0.178 0.025 6.216135e-217 CTL_MUT
## Arid5a 4.555256e-220 -1.3529522 0.188 0.038 1.366577e-216 CTL_MUT
## Kif18a 9.971305e-220 -1.7725932 0.172 0.005 2.991391e-216 CTL_MUT
## Irf1 3.389157e-219 -3.7003394 0.109 0.013 1.016747e-215 CTL_MUT
## Nrap 3.800432e-219 -3.5413450 0.143 0.015 1.140130e-215 CTL_MUT
## Gm49194 2.816790e-218 -3.9965867 0.182 0.002 8.450369e-215 CTL_MUT
## Tfpi 6.618786e-218 -5.4776348 0.135 0.009 1.985636e-214 CTL_MUT
## St8sia2 6.625354e-218 -4.0699919 0.140 0.013 1.987606e-214 CTL_MUT
## Ndrg2 1.063066e-217 -1.3260702 0.148 0.151 3.189199e-214 CTL_MUT
## Cped1 2.434428e-217 2.2823000 0.111 0.006 7.303285e-214 CTL_MUT
## Trp53i11 2.633684e-217 -3.6693472 0.205 0.062 7.901053e-214 CTL_MUT
## Rspo1 2.837033e-217 -5.1057867 0.125 0.008 8.511100e-214 CTL_MUT
## Mtmr11 9.842570e-217 -4.0498076 0.153 0.005 2.952771e-213 CTL_MUT
## Sox1ot 1.564021e-216 -2.8901026 0.147 0.009 4.692064e-213 CTL_MUT
## Cort 1.635173e-216 -2.6884511 0.101 0.037 4.905520e-213 CTL_MUT
## Cyp2j9 2.015258e-216 -2.7608070 0.105 0.017 6.045774e-213 CTL_MUT
## Otof 2.960751e-216 -3.7921423 0.152 0.011 8.882253e-213 CTL_MUT
## Gpld1 4.678937e-216 -3.0824906 0.117 0.022 1.403681e-212 CTL_MUT
## Sigirr 7.044583e-216 -3.1724397 0.104 0.005 2.113375e-212 CTL_MUT
## H2-K1 1.462130e-215 -3.0419530 0.119 0.043 4.386390e-212 CTL_MUT
## E230029C05Rik 1.734416e-215 -6.4046000 0.157 0.025 5.203248e-212 CTL_MUT
## Syde1 3.824641e-215 -3.2026858 0.118 0.003 1.147392e-211 CTL_MUT
## Pax6 1.102757e-214 -3.4914479 0.119 0.035 3.308272e-211 CTL_MUT
## Plxnb1 1.467246e-214 -1.5882151 0.147 0.027 4.401737e-211 CTL_MUT
## Mfge8 2.389541e-214 -1.5505027 0.133 0.136 7.168623e-211 CTL_MUT
## Nts 5.613704e-214 -3.2721822 0.110 0.013 1.684111e-210 CTL_MUT
## Hlx 2.465813e-213 -3.3330221 0.106 0.003 7.397439e-210 CTL_MUT
## Gm1604a 4.173336e-213 -2.7001178 0.171 0.008 1.252001e-209 CTL_MUT
## Maf 4.228071e-212 -3.5215452 0.157 0.034 1.268421e-208 CTL_MUT
## Smad5 4.258382e-211 -1.6397731 0.193 0.042 1.277514e-207 CTL_MUT
## Alpl 5.094867e-211 -3.7463516 0.109 0.006 1.528460e-207 CTL_MUT
## Mrvi1 1.341518e-210 -3.5073735 0.104 0.003 4.024553e-207 CTL_MUT
## Smo 5.316304e-210 -3.9942103 0.116 0.013 1.594891e-206 CTL_MUT
## Sox9 5.930352e-210 -2.3924240 0.169 0.051 1.779106e-206 CTL_MUT
## Agl 1.239239e-209 -3.2734334 0.193 0.047 3.717716e-206 CTL_MUT
## Dmkn 2.700064e-209 -5.3787469 0.112 0.021 8.100192e-206 CTL_MUT
## Dlgap5 3.949600e-209 -2.7582991 0.112 0.108 1.184880e-205 CTL_MUT
## Col3a1 7.704122e-209 -2.9714858 0.124 0.002 2.311237e-205 CTL_MUT
## Fndc1 7.059998e-208 -0.8442502 0.170 0.008 2.117999e-204 CTL_MUT
## Aif1l 1.075074e-207 -1.8567175 0.105 0.010 3.225221e-204 CTL_MUT
## Asic4 1.662092e-207 -3.4143886 0.128 0.011 4.986275e-204 CTL_MUT
## Gm27010 3.046692e-207 -4.5280684 0.186 0.004 9.140075e-204 CTL_MUT
## Mc5r 3.879678e-206 -3.9389988 0.185 0.002 1.163903e-202 CTL_MUT
## Gab1 1.286165e-205 -2.2429205 0.130 0.025 3.858496e-202 CTL_MUT
## Mustn1 1.605751e-205 -4.2785679 0.136 0.008 4.817252e-202 CTL_MUT
## Gpr37l1 5.388403e-205 -3.1789815 0.090 0.113 1.616521e-201 CTL_MUT
## Nid2 2.387770e-204 -3.1965345 0.135 0.002 7.163311e-201 CTL_MUT
## Jaml 3.448260e-204 -3.9752034 0.170 0.008 1.034478e-200 CTL_MUT
## Fgfr1 5.123462e-204 -1.8906769 0.153 0.055 1.537039e-200 CTL_MUT
## Pon2 6.534413e-204 -1.8683831 0.103 0.064 1.960324e-200 CTL_MUT
## Tcf7l1 1.515682e-203 -3.9615627 0.129 0.007 4.547046e-200 CTL_MUT
## Naprt 2.045759e-203 -3.6482520 0.120 0.007 6.137277e-200 CTL_MUT
## Slc52a3 2.963711e-203 -4.1846136 0.102 0.004 8.891132e-200 CTL_MUT
## S1pr1 3.021982e-202 -3.1610348 0.107 0.096 9.065945e-199 CTL_MUT
## Slc37a2 9.280266e-202 -3.8794286 0.101 0.005 2.784080e-198 CTL_MUT
## Gad1 1.707252e-201 -2.0747818 0.130 0.090 5.121757e-198 CTL_MUT
## Tril 2.604285e-201 -3.3634887 0.102 0.047 7.812854e-198 CTL_MUT
## Gbp3 4.938562e-201 -3.9892368 0.100 0.005 1.481569e-197 CTL_MUT
## Hif3a 5.036265e-201 -3.6230475 0.132 0.007 1.510880e-197 CTL_MUT
## Syk 6.390722e-201 -4.7594556 0.141 0.011 1.917217e-197 CTL_MUT
## Nostrin 1.638492e-200 -1.1606178 0.116 0.022 4.915475e-197 CTL_MUT
## Tspan2 4.649656e-200 -1.3635374 0.115 0.060 1.394897e-196 CTL_MUT
## Il11ra1 5.571602e-200 -2.6369228 0.222 0.046 1.671480e-196 CTL_MUT
## Arhgap31 1.022343e-199 -1.0227645 0.191 0.065 3.067030e-196 CTL_MUT
## Atp1a2 1.210011e-199 -0.3519552 0.162 0.194 3.630032e-196 CTL_MUT
## Cacna2d2 1.216096e-199 -0.7612776 0.171 0.069 3.648287e-196 CTL_MUT
## Cald1 2.027376e-199 0.9885624 0.145 0.093 6.082128e-196 CTL_MUT
## Hist1h2ac 4.312621e-199 -4.7475071 0.199 0.005 1.293786e-195 CTL_MUT
## Kcnj16 5.938968e-199 -2.5305205 0.112 0.015 1.781690e-195 CTL_MUT
## Gm9917 6.929618e-199 -2.6449938 0.139 0.006 2.078885e-195 CTL_MUT
## Chst5 9.149454e-199 -2.5297980 0.132 0.087 2.744836e-195 CTL_MUT
## Lyve1 2.437626e-198 -4.6157736 0.115 0.002 7.312879e-195 CTL_MUT
## Xaf1 5.215992e-198 -5.1454928 0.163 0.010 1.564797e-194 CTL_MUT
## Fgf1 7.450076e-198 -3.0236914 0.124 0.021 2.235023e-194 CTL_MUT
## Aldoc 1.200971e-197 -1.7713044 0.134 0.214 3.602912e-194 CTL_MUT
## Kcnh8 1.347043e-197 -4.3212942 0.134 0.003 4.041129e-194 CTL_MUT
## B4galt1 1.672554e-197 -4.4732629 0.128 0.015 5.017662e-194 CTL_MUT
## Cpm 4.307741e-197 -1.1800283 0.144 0.010 1.292322e-193 CTL_MUT
## Pex11g 4.604117e-197 -4.6430327 0.186 0.004 1.381235e-193 CTL_MUT
## Mfap4 4.921523e-197 -5.6867121 0.155 0.005 1.476457e-193 CTL_MUT
## Ctdsp1 2.189675e-196 -3.8334020 0.134 0.011 6.569025e-193 CTL_MUT
## Ctso 2.228284e-196 -4.9960290 0.135 0.030 6.684852e-193 CTL_MUT
## A2m 3.561580e-196 -3.8274318 0.100 0.009 1.068474e-192 CTL_MUT
## Igf2 9.262164e-196 -5.7207923 0.137 0.004 2.778649e-192 CTL_MUT
## Clec1a 1.816837e-195 -2.8959063 0.135 0.003 5.450512e-192 CTL_MUT
## Myo6 2.571370e-195 -1.3232730 0.182 0.092 7.714109e-192 CTL_MUT
## Ntsr2 4.168437e-195 -2.2914214 0.110 0.099 1.250531e-191 CTL_MUT
## Enpp1 7.742461e-195 -3.2849101 0.163 0.003 2.322738e-191 CTL_MUT
## Slc29a3 9.032637e-195 -3.8868455 0.131 0.026 2.709791e-191 CTL_MUT
## Edn1 4.936618e-194 -0.3065137 0.108 0.017 1.480985e-190 CTL_MUT
## Tagln 5.715997e-194 -5.7106185 0.123 0.005 1.714799e-190 CTL_MUT
## Ltbr 6.752221e-194 -1.2705777 0.122 0.010 2.025666e-190 CTL_MUT
## Thbs3 9.368701e-194 -3.2286160 0.147 0.017 2.810610e-190 CTL_MUT
## Cdk2 6.272867e-193 -4.2410952 0.140 0.003 1.881860e-189 CTL_MUT
## Gdpd3 1.059551e-192 -3.3563736 0.113 0.010 3.178653e-189 CTL_MUT
## Col11a1 1.157199e-192 -2.5989707 0.177 0.015 3.471596e-189 CTL_MUT
## Rhbdl2 1.374050e-192 -4.0754619 0.116 0.006 4.122151e-189 CTL_MUT
## Myof 2.024319e-192 -4.3543943 0.177 0.005 6.072956e-189 CTL_MUT
## Lamb2 2.042992e-192 -2.3949446 0.136 0.020 6.128976e-189 CTL_MUT
## Cntf 3.144762e-192 -5.0259323 0.171 0.003 9.434285e-189 CTL_MUT
## Tbc1d4 1.992203e-191 -1.9704042 0.131 0.018 5.976610e-188 CTL_MUT
## Frmd4b 2.051233e-191 -2.3710516 0.157 0.033 6.153700e-188 CTL_MUT
## Gramd3 2.637730e-191 -4.7799560 0.119 0.017 7.913191e-188 CTL_MUT
## Npy 4.744534e-191 -1.1807920 0.189 0.121 1.423360e-187 CTL_MUT
## Fam181b 5.504811e-191 -4.2441026 0.109 0.038 1.651443e-187 CTL_MUT
## Fcgr1 9.377173e-191 -1.0816172 0.110 0.006 2.813152e-187 CTL_MUT
## Osmr 1.033761e-190 -3.6068319 0.123 0.008 3.101282e-187 CTL_MUT
## Dennd3 1.836461e-190 -3.8284842 0.179 0.005 5.509384e-187 CTL_MUT
## Gstm1 2.140141e-190 -2.5557592 0.151 0.116 6.420424e-187 CTL_MUT
## Robo3 3.274916e-190 -3.1829085 0.178 0.022 9.824749e-187 CTL_MUT
## Heatr5a 3.418032e-190 -2.4613605 0.170 0.017 1.025410e-186 CTL_MUT
## Sema4b 3.974913e-190 -2.8638263 0.136 0.031 1.192474e-186 CTL_MUT
## Hfe 5.570587e-190 -3.1050880 0.118 0.007 1.671176e-186 CTL_MUT
## Slc44a1 1.588317e-189 -3.5277204 0.180 0.071 4.764950e-186 CTL_MUT
## Lama2 2.123990e-189 -3.7209781 0.137 0.014 6.371969e-186 CTL_MUT
## mt-Nd6 2.586344e-189 -4.3948204 0.231 0.100 7.759031e-186 CTL_MUT
## Smim3 4.531321e-189 -3.0821724 0.135 0.015 1.359396e-185 CTL_MUT
## Alkal2 4.717952e-189 -4.3315478 0.149 0.010 1.415386e-185 CTL_MUT
## Col24a1 9.446671e-189 -4.0951547 0.179 0.003 2.834001e-185 CTL_MUT
## Cysltr2 9.531319e-189 -1.5423533 0.101 0.003 2.859396e-185 CTL_MUT
## Smtn 1.715350e-188 -3.4020494 0.141 0.011 5.146051e-185 CTL_MUT
## Homer3 2.290824e-188 -4.0251932 0.194 0.007 6.872472e-185 CTL_MUT
## Hbb-bt 2.572196e-188 -2.2541494 0.199 0.082 7.716588e-185 CTL_MUT
## Mobp 3.203266e-188 0.7565918 0.124 0.117 9.609799e-185 CTL_MUT
## Pag1 3.796404e-188 -1.8292192 0.204 0.041 1.138921e-184 CTL_MUT
## Mgmt 2.543181e-187 -4.3973270 0.134 0.009 7.629544e-184 CTL_MUT
## Klf4 2.593079e-187 -1.9307690 0.147 0.069 7.779236e-184 CTL_MUT
## Lgi2 8.800725e-187 1.6550258 0.201 0.074 2.640218e-183 CTL_MUT
## Tmem204 9.481372e-187 -2.8530776 0.119 0.015 2.844412e-183 CTL_MUT
## Cpxm1 1.831110e-186 -2.5705809 0.138 0.011 5.493330e-183 CTL_MUT
## Ugdh 2.833479e-186 -3.0054272 0.174 0.044 8.500437e-183 CTL_MUT
## Axl 3.812819e-186 -1.7239633 0.129 0.012 1.143846e-182 CTL_MUT
## Sp140 5.230415e-186 -4.1069602 0.156 0.003 1.569124e-182 CTL_MUT
## Trim54 5.829516e-186 -4.2993802 0.108 0.009 1.748855e-182 CTL_MUT
## Gkn3 6.868504e-186 -5.4506246 0.183 0.004 2.060551e-182 CTL_MUT
## Mdfic 2.418669e-185 -4.0490600 0.142 0.004 7.256006e-182 CTL_MUT
## Bcan 6.015484e-185 -2.5070435 0.120 0.121 1.804645e-181 CTL_MUT
## Htr2c 1.047165e-184 -2.2115129 0.142 0.044 3.141494e-181 CTL_MUT
## Adarb2 1.933493e-184 -2.6239706 0.151 0.068 5.800480e-181 CTL_MUT
## Zfp57 5.527460e-184 -2.4102070 0.188 0.021 1.658238e-180 CTL_MUT
## Pdgfd 1.015430e-183 -1.5417961 0.148 0.002 3.046289e-180 CTL_MUT
## Slc16a4 1.752706e-183 -2.4295117 0.117 0.003 5.258118e-180 CTL_MUT
## Tmem170 7.269104e-183 -6.0413780 0.184 0.004 2.180731e-179 CTL_MUT
## Ston1 2.962137e-182 -4.5311572 0.135 0.002 8.886412e-179 CTL_MUT
## Vcl 1.079679e-181 -2.6086435 0.126 0.047 3.239037e-178 CTL_MUT
## Card19 1.657825e-181 -3.3668366 0.124 0.029 4.973476e-178 CTL_MUT
## Cd93 4.526969e-181 -1.0862498 0.110 0.022 1.358091e-177 CTL_MUT
## Pimreg 4.722707e-181 -1.5549753 0.137 0.005 1.416812e-177 CTL_MUT
## Zfp217 5.802688e-181 -4.2995018 0.206 0.003 1.740806e-177 CTL_MUT
## Abtb2 1.959157e-180 -2.7347688 0.136 0.009 5.877471e-177 CTL_MUT
## Slc4a4 1.990192e-180 -2.9529783 0.168 0.139 5.970576e-177 CTL_MUT
## Ezr 1.991731e-180 -0.2872345 0.107 0.052 5.975193e-177 CTL_MUT
## Sema3g 2.453575e-180 -4.7662605 0.106 0.020 7.360726e-177 CTL_MUT
## Snx33 2.805215e-180 -3.9784735 0.139 0.007 8.415644e-177 CTL_MUT
## Cyp4f14 6.312125e-180 -0.6647954 0.133 0.011 1.893637e-176 CTL_MUT
## Inhba 1.229225e-179 -4.2067365 0.150 0.032 3.687674e-176 CTL_MUT
## Mob3c 2.101948e-179 -1.8178596 0.148 0.017 6.305844e-176 CTL_MUT
## Rras 3.663351e-179 -2.8743745 0.158 0.043 1.099005e-175 CTL_MUT
## Ttyh2 4.032008e-179 -3.7762735 0.129 0.021 1.209602e-175 CTL_MUT
## Wfdc18 8.475577e-179 -3.5532883 0.111 0.030 2.542673e-175 CTL_MUT
## Trim12a 1.262837e-178 -3.0942846 0.111 0.003 3.788512e-175 CTL_MUT
## Ppic 1.962641e-178 -4.1033031 0.124 0.007 5.887923e-175 CTL_MUT
## Slc1a5 4.918129e-178 -3.0428587 0.125 0.003 1.475439e-174 CTL_MUT
## Ccdc102a 5.674462e-178 -3.6217645 0.128 0.004 1.702339e-174 CTL_MUT
## Ccm2l 1.251610e-177 -2.7654213 0.117 0.004 3.754830e-174 CTL_MUT
## Pdyn 1.372548e-177 -3.5350294 0.142 0.008 4.117645e-174 CTL_MUT
## Ulk4 1.395416e-177 -4.3940366 0.115 0.047 4.186249e-174 CTL_MUT
## Foxl2 1.518155e-177 -3.0061718 0.139 0.002 4.554466e-174 CTL_MUT
## Cbr3 1.736637e-177 -5.0091932 0.125 0.028 5.209912e-174 CTL_MUT
## Syt2 2.007359e-177 -3.5904415 0.133 0.007 6.022076e-174 CTL_MUT
## Tnnt1 2.563903e-177 -5.2909682 0.129 0.007 7.691709e-174 CTL_MUT
## Spin4 6.882249e-177 -3.7746646 0.104 0.050 2.064675e-173 CTL_MUT
## Hsd11b1 9.809131e-177 -3.7665447 0.117 0.017 2.942739e-173 CTL_MUT
## Egflam 1.687527e-176 -4.8737657 0.118 0.009 5.062582e-173 CTL_MUT
## Pcsk6 1.789377e-176 -2.7748148 0.140 0.009 5.368130e-173 CTL_MUT
## Creb5 7.546947e-176 -2.2954821 0.127 0.029 2.264084e-172 CTL_MUT
## Prdm16os 7.828460e-176 -0.2882622 0.135 0.012 2.348538e-172 CTL_MUT
## Gpam 8.801053e-176 0.3577104 0.117 0.040 2.640316e-172 CTL_MUT
## Rassf9 1.142988e-175 -3.6708826 0.114 0.007 3.428964e-172 CTL_MUT
## Aplnr 3.990038e-175 -3.2236792 0.134 0.002 1.197011e-171 CTL_MUT
## Smpdl3a 4.667729e-175 -5.0947764 0.184 0.092 1.400319e-171 CTL_MUT
## Wnt5b 5.524946e-175 -3.8295030 0.183 0.004 1.657484e-171 CTL_MUT
## Npc1 1.139015e-174 -6.0170788 0.192 0.071 3.417045e-171 CTL_MUT
## Cobll1 1.276945e-174 -3.3708893 0.104 0.013 3.830834e-171 CTL_MUT
## Gabrg1 1.563714e-174 -1.2761122 0.137 0.037 4.691143e-171 CTL_MUT
## Gng11 4.419185e-174 -0.8289319 0.116 0.044 1.325756e-170 CTL_MUT
## Rassf2 6.033838e-174 -2.4968483 0.158 0.019 1.810152e-170 CTL_MUT
## Serpine1 1.683179e-173 -4.9545727 0.133 0.004 5.049536e-170 CTL_MUT
## Slc6a11 2.288856e-173 -3.2969561 0.108 0.054 6.866568e-170 CTL_MUT
## Irf7 3.879686e-173 -4.1448631 0.105 0.005 1.163906e-169 CTL_MUT
## Plpp3 4.876712e-173 -0.2874674 0.114 0.154 1.463014e-169 CTL_MUT
## S100a1 8.332085e-173 -2.2357201 0.136 0.120 2.499625e-169 CTL_MUT
## Capg 9.065143e-173 -2.7624404 0.127 0.006 2.719543e-169 CTL_MUT
## Plod1 1.278877e-172 -0.5790238 0.152 0.031 3.836630e-169 CTL_MUT
## Apoe 3.843144e-172 -0.3064599 0.155 0.261 1.152943e-168 CTL_MUT
## Slc27a1 1.426912e-171 -1.2631535 0.152 0.068 4.280737e-168 CTL_MUT
## Nek2 1.627426e-171 -4.5863787 0.105 0.012 4.882279e-168 CTL_MUT
## Erg 2.071328e-171 -0.2637608 0.104 0.009 6.213985e-168 CTL_MUT
## Eya4 4.895663e-171 -3.4750130 0.178 0.009 1.468699e-167 CTL_MUT
## Pros1 7.547841e-171 -1.7953341 0.112 0.011 2.264352e-167 CTL_MUT
## Gimap5 9.220081e-171 -1.5269499 0.105 0.004 2.766024e-167 CTL_MUT
## B130024G19Rik 6.056213e-170 -3.0427717 0.128 0.003 1.816864e-166 CTL_MUT
## Mrc2 7.579911e-170 -4.0189898 0.135 0.003 2.273973e-166 CTL_MUT
## Ifit3b 7.699515e-170 -5.5416925 0.125 0.008 2.309854e-166 CTL_MUT
## Rab11fip1 1.811952e-169 -2.9359361 0.113 0.007 5.435855e-166 CTL_MUT
## S100a13 2.223482e-169 -0.3286822 0.123 0.065 6.670446e-166 CTL_MUT
## Cd40 1.606201e-168 -3.5086872 0.155 0.005 4.818602e-165 CTL_MUT
## Lama3 4.082251e-168 -4.5091066 0.203 0.004 1.224675e-164 CTL_MUT
## Zfp607a 6.615702e-168 -4.2992357 0.147 0.035 1.984711e-164 CTL_MUT
## Rhog 8.132703e-168 -3.2775562 0.144 0.031 2.439811e-164 CTL_MUT
## Tgfbr3 2.314483e-167 -3.8979955 0.201 0.007 6.943449e-164 CTL_MUT
## Hist1h2bc 3.037912e-167 -3.2980105 0.230 0.098 9.113735e-164 CTL_MUT
## Fhl4 3.822882e-167 -3.7811045 0.192 0.001 1.146865e-163 CTL_MUT
## Soga1 6.512967e-167 -2.2910305 0.142 0.022 1.953890e-163 CTL_MUT
## Cdc42ep2 1.042879e-166 -2.9687670 0.161 0.056 3.128638e-163 CTL_MUT
## Itpr2 1.805383e-166 -1.9610108 0.129 0.054 5.416150e-163 CTL_MUT
## Cdc20 2.358514e-166 -1.9577336 0.146 0.003 7.075542e-163 CTL_MUT
## Ccnb2 3.746579e-166 -1.9760788 0.129 0.008 1.123974e-162 CTL_MUT
## Gpr88 2.079016e-165 -3.7806135 0.156 0.051 6.237048e-162 CTL_MUT
## Wsb1 3.337030e-165 1.2123913 0.217 0.053 1.001109e-161 CTL_MUT
## Pf4 1.010122e-164 -5.6763841 0.133 0.003 3.030366e-161 CTL_MUT
## Lgr5 1.166217e-164 -4.3611768 0.134 0.020 3.498652e-161 CTL_MUT
## Dlx2 1.278454e-164 -3.0484705 0.100 0.022 3.835363e-161 CTL_MUT
## Zfp536 1.869182e-164 -2.0360287 0.161 0.054 5.607545e-161 CTL_MUT
## Plxnb2 2.346730e-164 -2.8606598 0.158 0.040 7.040189e-161 CTL_MUT
## Ndrg1 2.966421e-164 -1.4864380 0.154 0.052 8.899262e-161 CTL_MUT
## Fbxl22 4.043156e-164 -5.4430693 0.169 0.006 1.212947e-160 CTL_MUT
## Efnb3 5.359243e-164 -0.4109725 0.184 0.056 1.607773e-160 CTL_MUT
## Lacc1 6.087523e-164 -2.0893937 0.133 0.018 1.826257e-160 CTL_MUT
## Tec 1.107423e-163 -2.1714081 0.147 0.010 3.322270e-160 CTL_MUT
## Hvcn1 3.099301e-163 -3.9149388 0.122 0.014 9.297902e-160 CTL_MUT
## Cnksr3 3.797940e-163 -5.4536921 0.145 0.008 1.139382e-159 CTL_MUT
## Pappa2 5.239655e-163 -3.9226228 0.172 0.003 1.571896e-159 CTL_MUT
## Dusp2 3.507104e-162 -2.5639021 0.117 0.014 1.052131e-158 CTL_MUT
## Nupr1 3.603008e-162 -2.4594527 0.128 0.024 1.080902e-158 CTL_MUT
## Glul 5.379220e-162 -2.1968464 0.186 0.199 1.613766e-158 CTL_MUT
## Hspa12b 6.066057e-162 -4.8541767 0.118 0.008 1.819817e-158 CTL_MUT
## Grem1 1.414400e-161 -5.9985924 0.118 0.017 4.243199e-158 CTL_MUT
## Trh 3.270330e-161 -5.0263990 0.109 0.006 9.810990e-158 CTL_MUT
## Shroom4 6.219619e-161 -3.7577327 0.105 0.007 1.865886e-157 CTL_MUT
## Flvcr2 1.122531e-160 -2.9958397 0.130 0.003 3.367593e-157 CTL_MUT
## Sorbs3 1.376737e-160 -2.1472041 0.136 0.010 4.130210e-157 CTL_MUT
## Pcdh12 2.886886e-160 -2.5232018 0.153 0.002 8.660657e-157 CTL_MUT
## A930001M01Rik 3.015057e-160 -4.9368986 0.127 0.007 9.045171e-157 CTL_MUT
## Tprn 3.658330e-160 -4.5571324 0.128 0.016 1.097499e-156 CTL_MUT
## Caskin2 5.682193e-160 -2.8172667 0.132 0.017 1.704658e-156 CTL_MUT
## Rbp4 1.492875e-159 -2.7048014 0.175 0.062 4.478625e-156 CTL_MUT
## Slc7a11 1.614513e-159 -1.8368818 0.103 0.032 4.843539e-156 CTL_MUT
## Dab2 2.099978e-159 -2.5025245 0.126 0.013 6.299935e-156 CTL_MUT
## Ly6c1 3.180036e-159 -0.3734286 0.108 0.067 9.540107e-156 CTL_MUT
## Abca1 3.377451e-159 -0.8628750 0.134 0.040 1.013235e-155 CTL_MUT
## Nckap5 4.249254e-159 -2.4199850 0.176 0.032 1.274776e-155 CTL_MUT
## Plekhb1 5.525688e-159 -0.8033663 0.137 0.041 1.657706e-155 CTL_MUT
## Arpc1b 1.850704e-158 -2.7429153 0.125 0.050 5.552113e-155 CTL_MUT
## Gm29521 1.866851e-158 -4.7525646 0.116 0.002 5.600554e-155 CTL_MUT
## Tcf7l2 2.002162e-158 -4.0000073 0.110 0.023 6.006486e-155 CTL_MUT
## Gng5 4.536077e-158 -1.9730693 0.191 0.109 1.360823e-154 CTL_MUT
## Tent5a 4.972287e-158 -3.9485241 0.132 0.018 1.491686e-154 CTL_MUT
## St6galnac2 6.467151e-158 -4.2103009 0.114 0.006 1.940145e-154 CTL_MUT
## Col5a2 6.888445e-158 -3.3404122 0.195 0.004 2.066534e-154 CTL_MUT
## Col14a1 7.508760e-158 -3.4408043 0.131 0.019 2.252628e-154 CTL_MUT
## Serping1 8.258101e-158 -2.5256158 0.115 0.006 2.477430e-154 CTL_MUT
## Abcc4 1.214432e-157 -2.1213463 0.129 0.015 3.643295e-154 CTL_MUT
## Smox 1.772515e-157 -2.2417263 0.199 0.043 5.317545e-154 CTL_MUT
## AY036118 2.247690e-157 3.0840419 0.262 0.449 6.743069e-154 CTL_MUT
## Ano6 3.026184e-157 -4.3543878 0.231 0.046 9.078552e-154 CTL_MUT
## Hba-a2 4.693620e-157 -1.8793607 0.219 0.132 1.408086e-153 CTL_MUT
## Tgfb2 9.134264e-157 -1.6909268 0.169 0.044 2.740279e-153 CTL_MUT
## Gltp 9.494109e-157 -2.6722075 0.115 0.033 2.848233e-153 CTL_MUT
## Lgals1 1.346867e-156 -3.2496330 0.106 0.036 4.040601e-153 CTL_MUT
## Gm12840 1.666745e-156 -4.4032971 0.201 0.008 5.000236e-153 CTL_MUT
## Pcolce2 1.767597e-156 -4.2809589 0.139 0.010 5.302790e-153 CTL_MUT
## Mirt1 2.078028e-156 -4.7642785 0.175 0.008 6.234084e-153 CTL_MUT
## Gm9925 8.940483e-156 -1.5466989 0.148 0.050 2.682145e-152 CTL_MUT
## Lpcat2 1.095229e-155 -3.6968708 0.118 0.022 3.285688e-152 CTL_MUT
## Emcn 1.181629e-155 -3.5338857 0.109 0.020 3.544888e-152 CTL_MUT
## Fam129a 1.447061e-155 -4.6282702 0.101 0.008 4.341184e-152 CTL_MUT
## Soat1 2.374895e-155 1.0854007 0.161 0.067 7.124685e-152 CTL_MUT
## Gm17750 2.406593e-155 -4.1060606 0.127 0.032 7.219780e-152 CTL_MUT
## Spaar 3.991380e-155 -3.0818890 0.167 0.002 1.197414e-151 CTL_MUT
## Naaa 6.285027e-155 -3.3269510 0.171 0.012 1.885508e-151 CTL_MUT
## Mdk 7.547769e-155 -2.5251242 0.127 0.030 2.264331e-151 CTL_MUT
## Aebp1 8.026796e-155 -3.8552432 0.150 0.009 2.408039e-151 CTL_MUT
## Gm15998 8.910559e-155 -4.3416747 0.171 0.010 2.673168e-151 CTL_MUT
## Slc22a3 9.680326e-155 -5.7836630 0.147 0.009 2.904098e-151 CTL_MUT
## Alox5ap 1.046522e-154 -4.1768693 0.106 0.020 3.139566e-151 CTL_MUT
## Adgrg1 1.286005e-154 -3.0194180 0.167 0.048 3.858014e-151 CTL_MUT
## Ly75 1.637495e-154 -3.5402038 0.111 0.006 4.912485e-151 CTL_MUT
## Paqr8 1.936257e-154 -0.5380681 0.170 0.078 5.808771e-151 CTL_MUT
## Clic4 4.370111e-154 -2.4480587 0.148 0.040 1.311033e-150 CTL_MUT
## Kif4 4.558610e-154 0.6129164 0.124 0.002 1.367583e-150 CTL_MUT
## Fzd6 5.289331e-154 -4.4278493 0.110 0.009 1.586799e-150 CTL_MUT
## 5031425F14Rik 1.060696e-153 -4.5141556 0.146 0.004 3.182087e-150 CTL_MUT
## Dpysl5 1.141946e-153 -1.7172990 0.209 0.064 3.425839e-150 CTL_MUT
## Tmem252 1.474351e-153 0.6330276 0.111 0.014 4.423054e-150 CTL_MUT
## Tshz1 4.746043e-153 -5.2763869 0.165 0.070 1.423813e-149 CTL_MUT
## Golm1 4.875500e-153 -3.4330811 0.169 0.055 1.462650e-149 CTL_MUT
## Tacr1 5.849119e-153 -5.1559141 0.207 0.007 1.754736e-149 CTL_MUT
## Uba7 6.443009e-153 -3.9048185 0.127 0.004 1.932903e-149 CTL_MUT
## Cebpb 6.778208e-153 -2.7370905 0.193 0.034 2.033462e-149 CTL_MUT
## Elovl5 8.720732e-153 -3.4466251 0.164 0.044 2.616220e-149 CTL_MUT
## Rbp1 4.612591e-152 -3.5291403 0.162 0.018 1.383777e-148 CTL_MUT
## Emp2 4.654201e-152 -2.5934659 0.124 0.027 1.396260e-148 CTL_MUT
## Smc4 7.779420e-152 0.5240013 0.138 0.021 2.333826e-148 CTL_MUT
## Prr5 8.128735e-152 -3.2407145 0.105 0.018 2.438621e-148 CTL_MUT
## Cmtm3 1.008180e-151 -3.5618116 0.166 0.006 3.024541e-148 CTL_MUT
## Tsc22d4 1.306587e-151 -2.3385379 0.201 0.092 3.919761e-148 CTL_MUT
## Trps1 1.949632e-151 2.5123088 0.186 0.084 5.848895e-148 CTL_MUT
## S100a4 2.755646e-151 -3.4708817 0.114 0.008 8.266938e-148 CTL_MUT
## Ifngr1 2.915687e-151 -0.3184530 0.133 0.033 8.747060e-148 CTL_MUT
## Serpina9 3.395060e-151 -4.9597196 0.154 0.002 1.018518e-147 CTL_MUT
## Rin3 5.763491e-151 -4.1530568 0.109 0.007 1.729047e-147 CTL_MUT
## Plekhg1 8.889843e-151 -1.0592484 0.158 0.020 2.666953e-147 CTL_MUT
## Eva1b 1.167532e-150 -1.3880268 0.116 0.022 3.502595e-147 CTL_MUT
## Foxd1 1.769628e-150 -4.4027686 0.113 0.017 5.308883e-147 CTL_MUT
## Tmem91 2.009135e-150 0.8987046 0.218 0.104 6.027405e-147 CTL_MUT
## Tex15 2.248539e-150 -4.7691352 0.172 0.005 6.745618e-147 CTL_MUT
## Trim16 3.630938e-150 -3.1695714 0.111 0.007 1.089281e-146 CTL_MUT
## Nmb 5.925956e-150 -5.0212481 0.183 0.014 1.777787e-146 CTL_MUT
## Mbp 1.831374e-149 -0.3006982 0.204 0.263 5.494122e-146 CTL_MUT
## Afap1 2.360207e-149 -0.6406044 0.211 0.042 7.080620e-146 CTL_MUT
## Grid2ip 6.500200e-149 -5.5805777 0.103 0.022 1.950060e-145 CTL_MUT
## Tbxa2r 7.014267e-149 0.7765446 0.108 0.005 2.104280e-145 CTL_MUT
## Gm49767 1.119980e-148 -3.9363885 0.160 0.004 3.359941e-145 CTL_MUT
## Paqr6 3.018692e-148 -2.9203891 0.136 0.007 9.056077e-145 CTL_MUT
## Filip1 4.594541e-148 -1.3363698 0.173 0.033 1.378362e-144 CTL_MUT
## Lrp4 4.748248e-148 -2.8906028 0.137 0.011 1.424475e-144 CTL_MUT
## Gm37494 7.470608e-148 -0.3424484 0.227 0.046 2.241182e-144 CTL_MUT
## A230005M16Rik 1.345302e-147 -6.0504436 0.191 0.004 4.035905e-144 CTL_MUT
## Arhgef5 1.637532e-147 -3.3746918 0.127 0.007 4.912597e-144 CTL_MUT
## Hspa1b 2.223425e-147 -3.5269603 0.169 0.014 6.670275e-144 CTL_MUT
## Itga5 4.328892e-147 -4.0069711 0.152 0.005 1.298668e-143 CTL_MUT
## Hist1h2ap 4.757194e-147 -4.0172824 0.178 0.018 1.427158e-143 CTL_MUT
## Crot 6.887520e-147 -2.2709806 0.145 0.051 2.066256e-143 CTL_MUT
## Foxc1 8.415710e-147 -3.7740885 0.131 0.011 2.524713e-143 CTL_MUT
## Igfbp5 9.932836e-147 -3.9903384 0.211 0.077 2.979851e-143 CTL_MUT
## Tmem37 1.906968e-146 -3.1952482 0.110 0.011 5.720904e-143 CTL_MUT
## Lsr 3.395389e-146 -3.0775838 0.113 0.011 1.018617e-142 CTL_MUT
## Tnfsf9 4.170847e-146 -4.8365115 0.136 0.003 1.251254e-142 CTL_MUT
## Hpgds 9.274515e-146 -0.5845183 0.151 0.021 2.782354e-142 CTL_MUT
## Slc26a10 1.363543e-145 -5.7678558 0.127 0.017 4.090630e-142 CTL_MUT
## Phka1 2.010036e-145 -2.3337790 0.186 0.015 6.030107e-142 CTL_MUT
## Il4i1 2.657662e-145 -4.0725226 0.124 0.012 7.972987e-142 CTL_MUT
## Trim25 2.823768e-145 -2.0839451 0.137 0.009 8.471304e-142 CTL_MUT
## Ptch1 2.879413e-145 -2.6156383 0.229 0.071 8.638240e-142 CTL_MUT
## Rgs9 2.907056e-145 -5.0676804 0.192 0.034 8.721169e-142 CTL_MUT
## Cldn5 3.017261e-145 0.7501270 0.108 0.076 9.051783e-142 CTL_MUT
## Fbxo5 4.080326e-145 -4.9733897 0.116 0.004 1.224098e-141 CTL_MUT
## Heyl 5.659989e-145 -1.3557577 0.103 0.004 1.697997e-141 CTL_MUT
## Slc38a5 5.701928e-145 -3.8753385 0.102 0.014 1.710578e-141 CTL_MUT
## Gm42418 9.478876e-145 -2.6695753 0.302 0.410 2.843663e-141 CTL_MUT
## Slc7a7 1.139952e-144 -1.7758547 0.128 0.024 3.419856e-141 CTL_MUT
## Hmcn1 1.293833e-144 -2.8142641 0.114 0.017 3.881499e-141 CTL_MUT
## Kcnj8 1.676991e-144 -0.2514443 0.123 0.016 5.030972e-141 CTL_MUT
## Padi2 2.461652e-144 -3.7428511 0.143 0.014 7.384957e-141 CTL_MUT
## Rreb1 8.112963e-144 -3.7033132 0.196 0.015 2.433889e-140 CTL_MUT
## Tmcc3 8.900284e-144 -1.4265653 0.191 0.043 2.670085e-140 CTL_MUT
## Lgals9 1.171540e-143 -2.4366952 0.124 0.012 3.514619e-140 CTL_MUT
## Pth1r 1.295941e-143 -0.6785945 0.155 0.026 3.887824e-140 CTL_MUT
## Asb4 1.427947e-143 -2.8428609 0.108 0.004 4.283841e-140 CTL_MUT
## Icosl 3.394948e-143 -4.8940206 0.149 0.006 1.018484e-139 CTL_MUT
## Kcnc2 3.516145e-143 -1.5181755 0.174 0.063 1.054843e-139 CTL_MUT
## Gm11650 3.880393e-143 -5.1109280 0.145 0.009 1.164118e-139 CTL_MUT
## Cdc42ep1 5.255296e-143 -2.2696803 0.124 0.011 1.576589e-139 CTL_MUT
## Smco3 5.568908e-143 -7.9633364 0.117 0.009 1.670672e-139 CTL_MUT
## Notch3 6.433447e-143 -2.7928313 0.100 0.010 1.930034e-139 CTL_MUT
## Zfp36l2 7.021649e-143 -1.6462445 0.117 0.037 2.106495e-139 CTL_MUT
## Il10rb 2.563648e-142 -3.4763526 0.138 0.015 7.690943e-139 CTL_MUT
## Doc2g 3.503591e-142 -7.6471389 0.166 0.011 1.051077e-138 CTL_MUT
## Myct1 4.803313e-142 -2.8556983 0.129 0.002 1.440994e-138 CTL_MUT
## AU020206 1.185776e-141 -4.0052335 0.124 0.009 3.557327e-138 CTL_MUT
## St3gal6 1.264521e-141 -2.4340213 0.136 0.041 3.793564e-138 CTL_MUT
## Crybg1 1.549826e-141 -3.8600269 0.141 0.002 4.649478e-138 CTL_MUT
## Vim 2.260740e-141 -1.6915474 0.108 0.046 6.782220e-138 CTL_MUT
## Gm43581 2.614613e-141 -4.1024942 0.203 0.005 7.843840e-138 CTL_MUT
## Zfp36 5.751072e-141 -3.0834306 0.109 0.024 1.725322e-137 CTL_MUT
## Edn3 2.562019e-140 -3.4236868 0.137 0.007 7.686056e-137 CTL_MUT
## Luzp2 2.787985e-140 -0.7793493 0.186 0.151 8.363954e-137 CTL_MUT
## Sp100 1.006704e-139 -4.0019202 0.118 0.005 3.020111e-136 CTL_MUT
## AW551984 1.090840e-139 -5.6199008 0.165 0.008 3.272521e-136 CTL_MUT
## Gad2 1.284241e-139 -2.4012834 0.150 0.109 3.852724e-136 CTL_MUT
## Lmod1 1.981211e-139 -4.4332234 0.145 0.002 5.943632e-136 CTL_MUT
## Kank1 2.277132e-139 -3.0424179 0.124 0.030 6.831395e-136 CTL_MUT
## Crh 3.138832e-139 -2.7885211 0.129 0.012 9.416495e-136 CTL_MUT
## Glis3 3.829908e-139 -4.7065930 0.109 0.005 1.148972e-135 CTL_MUT
## Gm13625 6.512609e-139 -5.9460119 0.169 0.004 1.953783e-135 CTL_MUT
## Scd1 6.699018e-139 -1.7996781 0.167 0.031 2.009705e-135 CTL_MUT
## Nkain4 6.962684e-139 -0.9101924 0.180 0.061 2.088805e-135 CTL_MUT
## Meis1 8.206186e-139 -2.3124840 0.147 0.016 2.461856e-135 CTL_MUT
## Arx 9.220655e-139 -3.1015003 0.115 0.048 2.766196e-135 CTL_MUT
## Penk 9.668085e-139 -2.9570753 0.144 0.039 2.900426e-135 CTL_MUT
## Htra3 1.110577e-138 -2.2359535 0.154 0.004 3.331732e-135 CTL_MUT
## Myo10 1.236175e-138 -2.7723733 0.160 0.079 3.708525e-135 CTL_MUT
## Cdhr1 1.317350e-138 -7.0406740 0.155 0.009 3.952049e-135 CTL_MUT
## Pygb 1.937880e-138 -2.5547807 0.199 0.073 5.813639e-135 CTL_MUT
## Cryab 7.200881e-138 0.4075793 0.190 0.123 2.160264e-134 CTL_MUT
## Tmem163 1.031409e-137 -6.0629564 0.134 0.030 3.094226e-134 CTL_MUT
## Gpsm1 1.097297e-137 -8.0381628 0.188 0.055 3.291892e-134 CTL_MUT
## Il13ra1 1.370550e-137 -2.9999772 0.122 0.009 4.111650e-134 CTL_MUT
## Tead1 2.617998e-137 -3.2730234 0.218 0.044 7.853995e-134 CTL_MUT
## Gprc5b 2.752055e-137 -2.5307815 0.142 0.045 8.256166e-134 CTL_MUT
## Tlr12 3.806810e-137 -3.3000887 0.143 0.027 1.142043e-133 CTL_MUT
## Wscd1 4.566727e-137 -1.3367599 0.192 0.082 1.370018e-133 CTL_MUT
## Rgcc 5.515014e-137 -2.7443338 0.142 0.062 1.654504e-133 CTL_MUT
## Adam17 1.205107e-136 -1.3330823 0.162 0.033 3.615321e-133 CTL_MUT
## Lhfpl3 1.278198e-136 -3.3441980 0.116 0.069 3.834595e-133 CTL_MUT
## Sfxn5 1.397467e-136 -1.3230058 0.158 0.088 4.192400e-133 CTL_MUT
## Ndnf 1.542446e-136 -1.6311888 0.154 0.046 4.627339e-133 CTL_MUT
## Adssl1 1.723475e-136 -5.3745482 0.133 0.036 5.170426e-133 CTL_MUT
## Emilin1 2.567969e-136 -1.4766056 0.128 0.010 7.703908e-133 CTL_MUT
## Sgms2 2.959989e-136 -2.9501964 0.136 0.005 8.879967e-133 CTL_MUT
## Zic2 3.302757e-136 -3.0305857 0.115 0.016 9.908272e-133 CTL_MUT
## Gm32688 3.922565e-136 -3.1855835 0.160 0.002 1.176770e-132 CTL_MUT
## Brinp3 4.764244e-136 -0.8621565 0.222 0.113 1.429273e-132 CTL_MUT
## Hrct1 1.697771e-135 1.0561998 0.133 0.009 5.093314e-132 CTL_MUT
## Sln 2.452402e-135 -5.3922411 0.111 0.013 7.357207e-132 CTL_MUT
## Thsd7b 4.418962e-135 -2.9640587 0.189 0.016 1.325689e-131 CTL_MUT
## Ccdc88b 6.771373e-135 -4.4082780 0.104 0.016 2.031412e-131 CTL_MUT
## Itpr3 7.368598e-135 -4.4792533 0.144 0.004 2.210579e-131 CTL_MUT
## Ppp1r16b 1.467440e-134 -1.9965688 0.181 0.071 4.402321e-131 CTL_MUT
## Pde8a 9.339381e-134 -3.1459515 0.138 0.013 2.801814e-130 CTL_MUT
## Rrm2 1.167904e-133 -5.5230670 0.131 0.009 3.503713e-130 CTL_MUT
## Gatm 2.277216e-133 -2.0925003 0.154 0.052 6.831647e-130 CTL_MUT
## Tsix 4.109479e-133 2.7001433 0.267 0.084 1.232844e-129 CTL_MUT
## Iigp1 4.762461e-133 -4.9683887 0.104 0.038 1.428738e-129 CTL_MUT
## Plin2 7.251519e-133 -1.9288699 0.138 0.017 2.175456e-129 CTL_MUT
## Gm50107 7.816681e-133 -5.0087512 0.204 0.004 2.345004e-129 CTL_MUT
## Ptprz1 8.774988e-133 -0.4278702 0.144 0.177 2.632497e-129 CTL_MUT
## Hes5 1.890812e-132 -3.4727266 0.140 0.101 5.672436e-129 CTL_MUT
## Xlr 2.192613e-132 -4.6898475 0.153 0.033 6.577840e-129 CTL_MUT
## Chd7 3.299594e-132 -3.1238808 0.130 0.047 9.898781e-129 CTL_MUT
## Id3 8.023607e-132 -3.1987811 0.114 0.058 2.407082e-128 CTL_MUT
## Ddah2 9.944796e-132 -3.0849475 0.175 0.050 2.983439e-128 CTL_MUT
## Kcnip1 1.889969e-131 -4.7848440 0.137 0.036 5.669906e-128 CTL_MUT
## Irx3 1.924936e-131 -2.8059669 0.184 0.045 5.774807e-128 CTL_MUT
## Vcan 3.088258e-131 -0.9239570 0.148 0.066 9.264773e-128 CTL_MUT
## Castor1 5.355300e-131 -2.8974003 0.109 0.009 1.606590e-127 CTL_MUT
## Unc45b 1.094419e-130 -4.6059681 0.129 0.019 3.283257e-127 CTL_MUT
## Rin2 1.385635e-130 -2.1901072 0.172 0.034 4.156905e-127 CTL_MUT
## Nmi 2.251823e-130 -3.2202269 0.147 0.008 6.755469e-127 CTL_MUT
## Rhbdf2 4.263780e-130 -4.4036014 0.150 0.049 1.279134e-126 CTL_MUT
## Hmgcs2 5.631295e-130 -0.6532640 0.112 0.012 1.689389e-126 CTL_MUT
## Sox2 2.398434e-129 -3.2382216 0.136 0.095 7.195303e-126 CTL_MUT
## Rab3b 2.895176e-129 -3.9391129 0.168 0.055 8.685528e-126 CTL_MUT
## Vipr2 3.537437e-129 -3.7581487 0.163 0.006 1.061231e-125 CTL_MUT
## Frmd8 3.747836e-129 -4.2117464 0.196 0.016 1.124351e-125 CTL_MUT
## Onecut2 3.978404e-129 -3.1471900 0.215 0.018 1.193521e-125 CTL_MUT
## As3mt 1.030574e-128 -3.3639968 0.165 0.021 3.091721e-125 CTL_MUT
## Plxna4os1 3.023234e-128 -3.6897942 0.199 0.003 9.069702e-125 CTL_MUT
## Zc3h12a 3.838312e-128 -4.0471326 0.128 0.007 1.151494e-124 CTL_MUT
## Stxbp6 5.319921e-128 -4.6938818 0.210 0.116 1.595976e-124 CTL_MUT
## Sulf1 8.355368e-128 -2.9919256 0.212 0.021 2.506611e-124 CTL_MUT
## Svil 9.850452e-128 -2.6546772 0.223 0.018 2.955136e-124 CTL_MUT
## Tbx3 1.225616e-127 -1.9237796 0.112 0.011 3.676847e-124 CTL_MUT
## Endou 1.646993e-127 -4.3328377 0.151 0.003 4.940979e-124 CTL_MUT
## Ms4a6d 1.875289e-127 -5.0973339 0.130 0.003 5.625867e-124 CTL_MUT
## Sinhcaf 2.259724e-127 -1.2045084 0.208 0.029 6.779171e-124 CTL_MUT
## Firre 3.647381e-127 -2.5358162 0.176 0.022 1.094214e-123 CTL_MUT
## Lef1 7.058881e-127 -1.9855907 0.113 0.023 2.117664e-123 CTL_MUT
## Slco5a1 9.518266e-127 -2.6305399 0.167 0.011 2.855480e-123 CTL_MUT
## BC028528 9.810915e-127 -3.3207328 0.119 0.010 2.943275e-123 CTL_MUT
## Alas2 1.037637e-126 -4.9296758 0.123 0.009 3.112910e-123 CTL_MUT
## Gata2 1.037860e-126 -1.7089972 0.113 0.008 3.113581e-123 CTL_MUT
## Car5a 1.099684e-126 -3.7229152 0.112 0.007 3.299051e-123 CTL_MUT
## Vwf 1.247947e-126 -0.9888436 0.132 0.008 3.743842e-123 CTL_MUT
## Robo4 1.638806e-126 -0.8180779 0.108 0.011 4.916418e-123 CTL_MUT
## Gm47405 3.280127e-126 -2.5586599 0.173 0.022 9.840380e-123 CTL_MUT
## Slc7a5 4.136392e-126 -1.6130729 0.162 0.042 1.240918e-122 CTL_MUT
## Mical1 1.121279e-125 -3.7139445 0.133 0.008 3.363837e-122 CTL_MUT
## Cpeb4 1.126561e-125 -1.5719522 0.274 0.134 3.379683e-122 CTL_MUT
## Pxmp2 1.492227e-125 -2.0411311 0.189 0.012 4.476680e-122 CTL_MUT
## Gimap8 1.767181e-125 -2.0927478 0.149 0.014 5.301544e-122 CTL_MUT
## Serpinb6b 4.032160e-125 -2.2355690 0.102 0.006 1.209648e-121 CTL_MUT
## Cdca7 4.211295e-125 -3.8425065 0.102 0.014 1.263389e-121 CTL_MUT
## Pnlip 4.236619e-125 -4.4080117 0.159 0.081 1.270986e-121 CTL_MUT
## Usp54 3.326280e-124 -1.1601669 0.187 0.032 9.978841e-121 CTL_MUT
## Gstm2 7.565156e-124 -4.4631075 0.178 0.003 2.269547e-120 CTL_MUT
## Notch1 8.724939e-124 -1.0802981 0.133 0.035 2.617482e-120 CTL_MUT
## Dlx6os1 1.014255e-123 -2.1160808 0.126 0.057 3.042766e-120 CTL_MUT
## Pla2g4a 1.281322e-123 -4.2678916 0.129 0.008 3.843965e-120 CTL_MUT
## Apcdd1 1.287335e-123 -1.8972578 0.147 0.030 3.862005e-120 CTL_MUT
## Thsd1 8.041329e-123 -3.4592937 0.147 0.005 2.412399e-119 CTL_MUT
## Cyp4f16 1.581062e-122 -4.8688528 0.227 0.008 4.743187e-119 CTL_MUT
## 3222401L13Rik 1.690179e-122 -3.9092323 0.160 0.009 5.070537e-119 CTL_MUT
## Id1 5.038615e-122 -3.0407776 0.132 0.052 1.511584e-118 CTL_MUT
## Ly6a 7.851097e-122 -1.4947822 0.115 0.051 2.355329e-118 CTL_MUT
## Akap13 1.047908e-121 -3.7166600 0.232 0.080 3.143723e-118 CTL_MUT
## Prkch 2.449133e-121 -4.4885771 0.117 0.008 7.347400e-118 CTL_MUT
## Wfs1 3.419037e-121 -0.3077040 0.202 0.078 1.025711e-117 CTL_MUT
## Itprid2 3.799750e-121 -4.0927791 0.181 0.022 1.139925e-117 CTL_MUT
## Hmgb2 5.640067e-121 -1.2855487 0.174 0.044 1.692020e-117 CTL_MUT
## Mfap2 5.697947e-121 -2.1167363 0.154 0.012 1.709384e-117 CTL_MUT
## Trim47 5.723191e-121 -3.9462038 0.140 0.009 1.716957e-117 CTL_MUT
## Ccn1 1.048815e-120 -2.5735257 0.178 0.054 3.146446e-117 CTL_MUT
## Htr3a 1.589183e-120 -2.6518237 0.102 0.014 4.767550e-117 CTL_MUT
## 0610040J01Rik 1.630960e-120 -0.3780575 0.138 0.006 4.892881e-117 CTL_MUT
## Ece2 4.050690e-120 -2.2631758 0.221 0.032 1.215207e-116 CTL_MUT
## Kif19a 5.452412e-120 -1.2582855 0.103 0.011 1.635724e-116 CTL_MUT
## Jam3 1.089133e-119 -3.6800363 0.218 0.057 3.267400e-116 CTL_MUT
## Loxl2 1.852430e-119 -1.6469553 0.189 0.003 5.557289e-116 CTL_MUT
## Cox4i2 3.714746e-119 -0.9671368 0.119 0.011 1.114424e-115 CTL_MUT
## Esam 4.800310e-119 -2.7775793 0.151 0.034 1.440093e-115 CTL_MUT
## Lama5 6.779719e-119 -2.9734991 0.136 0.005 2.033916e-115 CTL_MUT
## Des 9.369787e-119 -2.5900143 0.125 0.006 2.810936e-115 CTL_MUT
## Cdc14a 9.792300e-119 -2.0057138 0.171 0.010 2.937690e-115 CTL_MUT
## Lrrk1 1.387726e-118 -2.5333953 0.119 0.007 4.163178e-115 CTL_MUT
## Pou3f1 2.366758e-118 -3.1785878 0.194 0.148 7.100274e-115 CTL_MUT
## Igsf11 2.937863e-118 -1.5049383 0.160 0.049 8.813589e-115 CTL_MUT
## Sox17 8.476959e-118 -1.2049465 0.127 0.010 2.543088e-114 CTL_MUT
## Tbx3os1 2.186415e-117 -2.7795189 0.130 0.018 6.559245e-114 CTL_MUT
## Idh2 5.300218e-117 -1.6257608 0.187 0.056 1.590065e-113 CTL_MUT
## Rbms3 6.454892e-117 -3.9038648 0.195 0.015 1.936468e-113 CTL_MUT
## Arhgef40 1.466615e-116 -3.5874238 0.172 0.033 4.399845e-113 CTL_MUT
## Adamts1 1.494910e-116 -3.9018046 0.155 0.032 4.484730e-113 CTL_MUT
## Pou3f4 1.911404e-116 -1.7445513 0.152 0.034 5.734211e-113 CTL_MUT
## Nid1 2.225528e-116 4.8943772 0.124 0.014 6.676583e-113 CTL_MUT
## Pde3a 2.796455e-116 -2.9956957 0.161 0.008 8.389365e-113 CTL_MUT
## Fcgrt 3.489667e-116 0.6291512 0.135 0.041 1.046900e-112 CTL_MUT
## Abcb1a 6.714287e-116 1.1190699 0.111 0.026 2.014286e-112 CTL_MUT
## Elfn1 9.768012e-116 -2.7326623 0.115 0.025 2.930404e-112 CTL_MUT
## Pou3f3 1.014193e-115 1.2661859 0.259 0.134 3.042579e-112 CTL_MUT
## Stxbp3 1.166657e-115 -2.0871980 0.180 0.029 3.499972e-112 CTL_MUT
## Tgm2 1.472448e-115 -1.7325222 0.118 0.009 4.417345e-112 CTL_MUT
## Sult1a1 2.572978e-115 -2.5595175 0.132 0.020 7.718934e-112 CTL_MUT
## Ifit1 2.867487e-115 -2.4799486 0.144 0.006 8.602462e-112 CTL_MUT
## Mfsd2a 2.933320e-115 -3.0916722 0.122 0.052 8.799961e-112 CTL_MUT
## Emx2os 3.947897e-115 -1.6948695 0.141 0.015 1.184369e-111 CTL_MUT
## Chst2 4.019868e-115 -2.8098867 0.214 0.111 1.205960e-111 CTL_MUT
## Ptpro 5.999155e-115 -5.8300739 0.159 0.071 1.799746e-111 CTL_MUT
## Ceacam1 7.164454e-115 -4.9678736 0.118 0.007 2.149336e-111 CTL_MUT
## Wfdc1 1.440719e-114 -1.1767692 0.132 0.020 4.322157e-111 CTL_MUT
## Foxq1 1.687791e-114 0.6740032 0.132 0.024 5.063373e-111 CTL_MUT
## St8sia4 1.987077e-114 -1.0525513 0.189 0.033 5.961232e-111 CTL_MUT
## Scamp2 2.193520e-114 -2.5645146 0.227 0.076 6.580561e-111 CTL_MUT
## Pecam1 2.492994e-114 -0.4877690 0.115 0.025 7.478981e-111 CTL_MUT
## Rnd2 4.634292e-114 -3.2858228 0.171 0.068 1.390288e-110 CTL_MUT
## Itga6 8.809256e-114 -2.0957043 0.159 0.046 2.642777e-110 CTL_MUT
## Gm16499.1 1.400277e-113 -4.8173973 0.210 0.004 4.200832e-110 CTL_MUT
## E130114P18Rik 3.112143e-113 -3.9559848 0.132 0.013 9.336429e-110 CTL_MUT
## Clec10a 3.574057e-113 -5.2649810 0.138 0.004 1.072217e-109 CTL_MUT
## Spock3 4.020674e-113 -4.2191634 0.202 0.069 1.206202e-109 CTL_MUT
## Carhsp1 1.358444e-112 -2.3933121 0.173 0.031 4.075332e-109 CTL_MUT
## Ifi30 1.655357e-112 -3.0927311 0.113 0.012 4.966072e-109 CTL_MUT
## Pnp 3.679116e-112 -2.2010334 0.170 0.039 1.103735e-108 CTL_MUT
## Cdh5 5.707694e-112 -1.1707450 0.108 0.016 1.712308e-108 CTL_MUT
## Nfkb1 6.518786e-112 -2.5031850 0.207 0.035 1.955636e-108 CTL_MUT
## Vamp8 7.594727e-112 -4.0069948 0.126 0.029 2.278418e-108 CTL_MUT
## Tes 8.255666e-112 -2.9172628 0.117 0.013 2.476700e-108 CTL_MUT
## Atp1b2 1.095399e-111 -0.8472447 0.216 0.140 3.286196e-108 CTL_MUT
## Adcy4 1.252998e-111 -0.9137191 0.144 0.007 3.758993e-108 CTL_MUT
## Casp8 1.302442e-111 -2.8363294 0.116 0.007 3.907327e-108 CTL_MUT
## Rtp4 1.453635e-111 -3.5028255 0.148 0.005 4.360905e-108 CTL_MUT
## Cpq 1.495793e-111 -0.7521442 0.130 0.019 4.487380e-108 CTL_MUT
## Sash1 6.114867e-111 -2.2587468 0.186 0.075 1.834460e-107 CTL_MUT
## Baiap3 6.951960e-111 -4.7426810 0.183 0.006 2.085588e-107 CTL_MUT
## Sat1 1.428961e-110 -1.7529443 0.195 0.121 4.286882e-107 CTL_MUT
## Pbld1 1.892421e-110 -5.4216059 0.206 0.006 5.677263e-107 CTL_MUT
## Zfhx3 2.151347e-110 -2.8589521 0.161 0.028 6.454040e-107 CTL_MUT
## Polr3e 4.408150e-110 -3.5140658 0.164 0.049 1.322445e-106 CTL_MUT
## Mecom 4.732210e-110 0.6996539 0.127 0.020 1.419663e-106 CTL_MUT
## Pglyrp1 5.753415e-110 -1.6154831 0.126 0.046 1.726024e-106 CTL_MUT
## Apobec3 9.343269e-110 -0.7550193 0.116 0.006 2.802981e-106 CTL_MUT
## Flna 1.643999e-109 -1.9763243 0.222 0.037 4.931998e-106 CTL_MUT
## Tpx2 1.920007e-109 0.8303158 0.132 0.011 5.760020e-106 CTL_MUT
## Eps8 2.002801e-109 -2.5582962 0.169 0.057 6.008403e-106 CTL_MUT
## Hspa1a 2.328633e-109 -1.6660128 0.192 0.040 6.985899e-106 CTL_MUT
## Stard9 4.075567e-109 -2.5586875 0.263 0.023 1.222670e-105 CTL_MUT
## Knstrn 8.435180e-109 -2.6030768 0.195 0.004 2.530554e-105 CTL_MUT
## Tgfa 1.392924e-108 -2.2302377 0.147 0.015 4.178772e-105 CTL_MUT
## Akna 2.271927e-108 -3.9323261 0.137 0.005 6.815782e-105 CTL_MUT
## Pard3b 2.679558e-108 -3.3456170 0.219 0.010 8.038673e-105 CTL_MUT
## Mif4gd 2.728802e-108 -2.1609247 0.173 0.019 8.186405e-105 CTL_MUT
## Adra1b 1.502919e-107 -2.7122036 0.213 0.083 4.508757e-104 CTL_MUT
## Ptgs1 2.446266e-107 -0.3872768 0.151 0.025 7.338798e-104 CTL_MUT
## Cp 7.037431e-107 -0.4011902 0.137 0.014 2.111229e-103 CTL_MUT
## Nek7 1.016478e-106 -0.5902990 0.176 0.036 3.049434e-103 CTL_MUT
## Gpc2 1.038193e-106 -3.7625641 0.123 0.014 3.114578e-103 CTL_MUT
## Skil 1.153340e-106 -4.0355336 0.274 0.172 3.460020e-103 CTL_MUT
## Sox7 1.169395e-106 -2.9322203 0.152 0.006 3.508186e-103 CTL_MUT
## AA387883 1.510547e-106 -1.2176719 0.104 0.015 4.531640e-103 CTL_MUT
## Cdc42ep4 1.578053e-106 -1.3654667 0.116 0.019 4.734159e-103 CTL_MUT
## Abca4 1.591660e-106 -4.7588253 0.175 0.138 4.774980e-103 CTL_MUT
## Rassf4 2.619225e-106 -3.8206498 0.141 0.018 7.857675e-103 CTL_MUT
## Sv2c 3.160534e-106 -2.6017230 0.170 0.031 9.481603e-103 CTL_MUT
## Sparc 3.201283e-106 -0.2521817 0.148 0.140 9.603850e-103 CTL_MUT
## Hjurp 4.190294e-106 1.8736765 0.249 0.061 1.257088e-102 CTL_MUT
## Tgif2 4.745707e-106 -3.7843341 0.167 0.003 1.423712e-102 CTL_MUT
## D17H6S53E 4.980875e-106 -3.5878776 0.138 0.034 1.494262e-102 CTL_MUT
## Atf3 5.962221e-106 -3.5486763 0.138 0.068 1.788666e-102 CTL_MUT
## Reep3 8.318333e-106 -1.9762053 0.234 0.084 2.495500e-102 CTL_MUT
## Adgrf5 9.058657e-106 -3.0149887 0.132 0.027 2.717597e-102 CTL_MUT
## Hcrtr2 1.001006e-105 -4.5937010 0.195 0.008 3.003019e-102 CTL_MUT
## Hspg2 1.219319e-105 -2.0858284 0.140 0.009 3.657958e-102 CTL_MUT
## Hes1 1.572307e-105 -2.5414611 0.238 0.107 4.716921e-102 CTL_MUT
## Kctd12b 1.654852e-105 -2.6209878 0.155 0.010 4.964557e-102 CTL_MUT
## Gch1 1.980201e-105 -3.9989719 0.129 0.008 5.940602e-102 CTL_MUT
## Cux2 2.562087e-105 -1.4061672 0.185 0.091 7.686261e-102 CTL_MUT
## Kif26a 4.542940e-105 -3.3070096 0.168 0.019 1.362882e-101 CTL_MUT
## Gng4 4.892266e-105 -4.0381892 0.180 0.082 1.467680e-101 CTL_MUT
## Tinagl1 5.354244e-105 -2.9695890 0.144 0.007 1.606273e-101 CTL_MUT
## Ranbp3l 6.127383e-105 -3.1638223 0.103 0.012 1.838215e-101 CTL_MUT
## Adra1a 6.358326e-105 -2.3151227 0.221 0.040 1.907498e-101 CTL_MUT
## Cavin2 2.842060e-104 -1.6718351 0.134 0.030 8.526180e-101 CTL_MUT
## Lgr6 3.303679e-104 -3.0908255 0.183 0.008 9.911037e-101 CTL_MUT
## Trpm3 3.894039e-104 -1.9811969 0.164 0.037 1.168212e-100 CTL_MUT
## Ctla2b 4.342725e-104 -2.2610328 0.113 0.012 1.302817e-100 CTL_MUT
## Gm26930 4.552091e-104 -1.7936984 0.172 0.018 1.365627e-100 CTL_MUT
## C1qtnf2 5.974055e-104 -3.4642836 0.108 0.021 1.792217e-100 CTL_MUT
## Eif2ak2 8.916868e-104 -4.2361221 0.182 0.012 2.675061e-100 CTL_MUT
## Nhsl1 1.245532e-103 -3.3269296 0.158 0.029 3.736597e-100 CTL_MUT
## Isg15 2.182448e-103 -3.8704663 0.134 0.014 6.547344e-100 CTL_MUT
## Serpinh1 3.453180e-103 -1.5410906 0.130 0.029 1.035954e-99 CTL_MUT
## H2-T24 3.618638e-103 -3.5429594 0.143 0.018 1.085591e-99 CTL_MUT
## Mafk 5.381404e-103 -1.8971544 0.187 0.029 1.614421e-99 CTL_MUT
## Hspb1 9.163641e-103 -1.4872472 0.141 0.049 2.749092e-99 CTL_MUT
## Reln 9.783962e-103 -2.6592067 0.162 0.038 2.935189e-99 CTL_MUT
## Gpx8 1.903129e-102 -3.1710569 0.115 0.011 5.709387e-99 CTL_MUT
## Crybg3 2.175768e-102 -2.1331826 0.141 0.020 6.527304e-99 CTL_MUT
## Gm3248 2.672632e-102 -4.3311629 0.128 0.066 8.017895e-99 CTL_MUT
## Ighm 4.486057e-102 -5.3609762 0.165 0.039 1.345817e-98 CTL_MUT
## Ldlr 6.053484e-102 -0.4932827 0.231 0.044 1.816045e-98 CTL_MUT
## Peli2 7.815573e-102 -2.3768405 0.222 0.040 2.344672e-98 CTL_MUT
## Fam89a 7.961484e-102 -3.4283593 0.152 0.003 2.388445e-98 CTL_MUT
## Dock6 8.584513e-102 -2.8406626 0.179 0.008 2.575354e-98 CTL_MUT
## Plce1 9.138039e-102 -2.3369135 0.140 0.018 2.741412e-98 CTL_MUT
## Gstm7 1.278607e-101 -2.0214179 0.184 0.050 3.835822e-98 CTL_MUT
## Cidea 1.300976e-101 -3.0863275 0.173 0.027 3.902927e-98 CTL_MUT
## Sh3bp4 1.348969e-101 -3.4039600 0.192 0.030 4.046906e-98 CTL_MUT
## Ace2 1.578302e-101 2.0257108 0.112 0.017 4.734907e-98 CTL_MUT
## Mt1 3.835590e-101 -0.4832912 0.206 0.304 1.150677e-97 CTL_MUT
## Slc30a10 6.665116e-101 -1.2170503 0.205 0.062 1.999535e-97 CTL_MUT
## Kit 8.138728e-101 -1.6644346 0.128 0.036 2.441618e-97 CTL_MUT
## Nkd1 1.025194e-100 -2.8805343 0.184 0.025 3.075583e-97 CTL_MUT
## Cmtm8 1.073186e-100 -2.7422173 0.130 0.012 3.219558e-97 CTL_MUT
## Dock1 1.297190e-100 -0.6620776 0.128 0.036 3.891570e-97 CTL_MUT
## Csf3r 1.346606e-100 -1.1427290 0.104 0.012 4.039817e-97 CTL_MUT
## Ahnak 1.724657e-100 -1.3315622 0.128 0.035 5.173971e-97 CTL_MUT
## Ascl1 1.900776e-100 -1.6304792 0.181 0.018 5.702328e-97 CTL_MUT
## Pltp 2.044102e-100 -1.1360217 0.125 0.060 6.132306e-97 CTL_MUT
## Plekho2 2.187710e-100 -3.2963081 0.175 0.017 6.563131e-97 CTL_MUT
## Vsig10 2.201791e-100 -3.1943944 0.130 0.010 6.605373e-97 CTL_MUT
## Adgre5 2.234714e-100 -1.5548797 0.139 0.012 6.704141e-97 CTL_MUT
## Stat4 2.493862e-100 -4.8813969 0.196 0.003 7.481585e-97 CTL_MUT
## Nat8f4 3.053400e-100 -4.2308741 0.124 0.007 9.160199e-97 CTL_MUT
## Slco1c1 3.111502e-100 -2.2479150 0.145 0.075 9.334506e-97 CTL_MUT
## Klhl5 3.797602e-100 -2.4617348 0.185 0.071 1.139280e-96 CTL_MUT
## Itih5 5.560689e-100 -3.1360976 0.120 0.033 1.668207e-96 CTL_MUT
## Kctd12 1.532872e-99 -3.8877979 0.215 0.086 4.598617e-96 CTL_MUT
## Creb3l2 1.589092e-99 -3.7430760 0.201 0.020 4.767275e-96 CTL_MUT
## Spon1 2.796536e-99 2.0556473 0.268 0.146 8.389608e-96 CTL_MUT
## Frmd7 3.004681e-99 -6.6446442 0.136 0.025 9.014044e-96 CTL_MUT
## Cnn2 3.704239e-99 -2.8249186 0.142 0.008 1.111272e-95 CTL_MUT
## Tmem45a 3.765008e-99 -2.3940779 0.174 0.008 1.129503e-95 CTL_MUT
## Wfdc17 3.880224e-99 -4.4605392 0.172 0.002 1.164067e-95 CTL_MUT
## Jam2 4.535492e-99 -1.2459676 0.146 0.037 1.360648e-95 CTL_MUT
## Tubb2b 5.910101e-99 -0.5038889 0.206 0.181 1.773030e-95 CTL_MUT
## Irf8 1.025024e-98 -2.5325529 0.139 0.024 3.075072e-95 CTL_MUT
## Nfatc2 2.416195e-98 -3.0203801 0.192 0.040 7.248585e-95 CTL_MUT
## Serpine2 3.374668e-98 -3.4606804 0.211 0.171 1.012400e-94 CTL_MUT
## Vangl1 6.215326e-98 -3.5225148 0.176 0.009 1.864598e-94 CTL_MUT
## Pla1a 6.847841e-98 -2.2149052 0.123 0.025 2.054352e-94 CTL_MUT
## Wls 7.439054e-98 -1.9040498 0.244 0.113 2.231716e-94 CTL_MUT
## Prdx6 8.362425e-98 -2.7824910 0.240 0.207 2.508727e-94 CTL_MUT
## Hba-a1 1.690612e-97 -2.1944427 0.225 0.156 5.071837e-94 CTL_MUT
## Trim56 1.905971e-97 -4.5917410 0.148 0.009 5.717912e-94 CTL_MUT
## Slc24a5 2.419051e-97 -5.2688154 0.197 0.105 7.257153e-94 CTL_MUT
## Srgn 2.845070e-97 -0.7603575 0.103 0.032 8.535209e-94 CTL_MUT
## Ehd4 2.906585e-97 -3.1842697 0.186 0.051 8.719755e-94 CTL_MUT
## Six3 3.083480e-97 -8.4156922 0.215 0.002 9.250440e-94 CTL_MUT
## Aspn 3.282537e-97 -2.2911404 0.133 0.014 9.847611e-94 CTL_MUT
## Tnfaip3 7.630727e-97 -3.9802912 0.143 0.017 2.289218e-93 CTL_MUT
## Gm26532 8.226804e-97 -1.4696030 0.203 0.076 2.468041e-93 CTL_MUT
## Tspo 9.165955e-97 -2.7280726 0.155 0.027 2.749786e-93 CTL_MUT
## Unc13c 9.670359e-97 -2.4233913 0.190 0.028 2.901108e-93 CTL_MUT
## Slco1a4 1.076780e-96 -0.5673347 0.111 0.041 3.230340e-93 CTL_MUT
## Mpzl1 2.453789e-96 -3.5723620 0.163 0.046 7.361367e-93 CTL_MUT
## Ctsw 3.108807e-96 -2.7154582 0.209 0.001 9.326422e-93 CTL_MUT
## Dbi 3.610401e-96 -2.0128342 0.218 0.259 1.083120e-92 CTL_MUT
## Cavin1 5.335290e-96 -2.7255416 0.138 0.012 1.600587e-92 CTL_MUT
## Rasgrp2 6.934829e-96 -0.8269593 0.179 0.062 2.080449e-92 CTL_MUT
## Gm45623 7.477209e-96 -5.1791878 0.144 0.007 2.243163e-92 CTL_MUT
## Dll4 1.107017e-95 -3.5968675 0.153 0.003 3.321051e-92 CTL_MUT
## Tnfrsf19 1.287182e-95 -3.9023394 0.204 0.061 3.861546e-92 CTL_MUT
## Acadl 1.790662e-95 -1.2972960 0.159 0.046 5.371987e-92 CTL_MUT
## Megf11 3.704084e-95 -2.2437870 0.165 0.023 1.111225e-91 CTL_MUT
## Enho 4.471964e-95 -2.4678459 0.268 0.204 1.341589e-91 CTL_MUT
## Tm4sf1 5.520064e-95 -2.7482920 0.136 0.026 1.656019e-91 CTL_MUT
## Gm36988 2.023620e-94 -2.4545853 0.180 0.023 6.070859e-91 CTL_MUT
## Ephx1 2.202371e-94 0.3501907 0.202 0.024 6.607113e-91 CTL_MUT
## Mndal 2.384893e-94 -3.3018961 0.173 0.007 7.154678e-91 CTL_MUT
## Lmo2 2.418542e-94 -2.7207915 0.182 0.024 7.255626e-91 CTL_MUT
## Dleu2 3.109737e-94 -1.1028843 0.218 0.096 9.329211e-91 CTL_MUT
## Kdm6b 3.320120e-94 -2.9000170 0.233 0.079 9.960359e-91 CTL_MUT
## Calb1 3.633865e-94 -4.1359899 0.240 0.216 1.090160e-90 CTL_MUT
## Zfp366 3.781978e-94 -2.3358571 0.133 0.008 1.134593e-90 CTL_MUT
## Mxra7 4.277205e-94 -2.3079289 0.181 0.033 1.283162e-90 CTL_MUT
## Elovl7 5.295458e-94 -4.1214819 0.152 0.037 1.588637e-90 CTL_MUT
## Tmem51 5.528993e-94 -3.7385650 0.155 0.007 1.658698e-90 CTL_MUT
## Selenop 9.325194e-94 -0.8660307 0.153 0.105 2.797558e-90 CTL_MUT
## Zfp36l1 9.687386e-94 -1.9401485 0.168 0.066 2.906216e-90 CTL_MUT
## 2810468N07Rik 2.478064e-93 -4.6694828 0.201 0.064 7.434191e-90 CTL_MUT
## Nrarp 2.660777e-93 -0.9331754 0.126 0.015 7.982332e-90 CTL_MUT
## Rab31 6.760564e-93 -3.4554633 0.173 0.040 2.028169e-89 CTL_MUT
## Stra6 6.837416e-93 -3.5300383 0.172 0.003 2.051225e-89 CTL_MUT
## Itgav 7.917304e-93 -2.4474195 0.240 0.107 2.375191e-89 CTL_MUT
## Adgrl4 1.080866e-92 -3.1711269 0.122 0.042 3.242598e-89 CTL_MUT
## Hipk2 1.185178e-92 -3.6329708 0.247 0.108 3.555535e-89 CTL_MUT
## Nacc2 1.745023e-92 2.5504981 0.201 0.068 5.235070e-89 CTL_MUT
## Plscr4 2.616940e-92 -5.0162785 0.189 0.007 7.850821e-89 CTL_MUT
## Tgfbr1 2.781083e-92 -3.8237397 0.155 0.042 8.343248e-89 CTL_MUT
## Akap12 2.807489e-92 -2.9139193 0.158 0.066 8.422466e-89 CTL_MUT
## Igf1 3.395150e-92 -1.1291369 0.127 0.026 1.018545e-88 CTL_MUT
## Kcnn2 4.995443e-92 -2.5540520 0.222 0.094 1.498633e-88 CTL_MUT
## Frem1 1.821580e-91 -3.8706092 0.224 0.005 5.464741e-88 CTL_MUT
## Gkap1 3.560691e-91 3.1939637 0.265 0.108 1.068207e-87 CTL_MUT
## Nos1 4.519238e-91 -4.3441353 0.181 0.036 1.355772e-87 CTL_MUT
## Npw 8.953313e-91 -3.5350833 0.132 0.012 2.685994e-87 CTL_MUT
## Gpc5 1.108004e-90 -1.8841705 0.125 0.046 3.324013e-87 CTL_MUT
## Gja4 1.402807e-90 -1.6825943 0.133 0.013 4.208422e-87 CTL_MUT
## Cks2 1.423355e-90 -0.3986553 0.144 0.010 4.270065e-87 CTL_MUT
## Pnpla7 1.525687e-90 -4.1340719 0.214 0.015 4.577061e-87 CTL_MUT
## Ttc28 2.639872e-90 -2.1889503 0.224 0.053 7.919617e-87 CTL_MUT
## Cyyr1 2.756143e-90 -1.2906533 0.115 0.018 8.268428e-87 CTL_MUT
## Foxo1 3.381737e-90 -4.4948174 0.187 0.036 1.014521e-86 CTL_MUT
## Plaur 5.174676e-90 -3.4560025 0.114 0.009 1.552403e-86 CTL_MUT
## Gm47423 6.627976e-90 -2.8641354 0.265 0.081 1.988393e-86 CTL_MUT
## Hist1h1c 1.218361e-89 -2.5059366 0.170 0.046 3.655083e-86 CTL_MUT
## Pln 1.373878e-89 -4.5131079 0.173 0.004 4.121633e-86 CTL_MUT
## Odf3b 1.442849e-89 -3.5445422 0.169 0.047 4.328546e-86 CTL_MUT
## Trhr 1.754718e-89 -2.9939757 0.170 0.007 5.264154e-86 CTL_MUT
## Pcdh18 2.021097e-89 -2.6265678 0.153 0.016 6.063291e-86 CTL_MUT
## Epcam 2.417953e-89 -0.8174881 0.110 0.034 7.253860e-86 CTL_MUT
## Tenm3 4.900519e-89 -2.9318691 0.236 0.105 1.470156e-85 CTL_MUT
## Gpr6 6.341916e-89 -5.5962456 0.194 0.002 1.902575e-85 CTL_MUT
## Qk 7.022427e-89 -2.1341669 0.244 0.255 2.106728e-85 CTL_MUT
## Anxa2 3.671295e-88 -3.3021170 0.173 0.016 1.101388e-84 CTL_MUT
## Tpm2 4.271706e-88 -3.3132637 0.145 0.014 1.281512e-84 CTL_MUT
## Gm4724 4.374748e-88 -4.2021999 0.130 0.065 1.312424e-84 CTL_MUT
## Irf9 4.755309e-88 -5.1629788 0.224 0.014 1.426593e-84 CTL_MUT
## Synpr 6.661925e-88 -3.8779923 0.209 0.115 1.998577e-84 CTL_MUT
## Adora2a 1.046907e-87 -4.6660656 0.200 0.004 3.140721e-84 CTL_MUT
## Kdr 2.311389e-87 -2.3012321 0.156 0.022 6.934166e-84 CTL_MUT
## Rpp25 2.947665e-87 -1.7221005 0.157 0.045 8.842995e-84 CTL_MUT
## Adcyap1r1 3.942417e-87 -0.8537429 0.245 0.089 1.182725e-83 CTL_MUT
## Tuba1c 4.537126e-87 -1.6625454 0.139 0.008 1.361138e-83 CTL_MUT
## Dkkl1 5.504379e-87 -0.2649216 0.216 0.084 1.651314e-83 CTL_MUT
## Rest 9.003305e-87 -3.5785613 0.181 0.019 2.700992e-83 CTL_MUT
## N4bp2 9.619894e-87 -3.5040745 0.246 0.019 2.885968e-83 CTL_MUT
## Kank2 1.132322e-86 -3.6050680 0.144 0.009 3.396965e-83 CTL_MUT
## Cdkn1b 1.200806e-86 -0.2703624 0.264 0.116 3.602419e-83 CTL_MUT
## Fosl2 1.434563e-86 -3.4374664 0.212 0.051 4.303690e-83 CTL_MUT
## Ushbp1 2.002868e-86 -1.6796675 0.117 0.010 6.008605e-83 CTL_MUT
## Sall1 2.900031e-86 -2.7926551 0.157 0.017 8.700094e-83 CTL_MUT
## Epha10 3.417702e-86 -4.0421400 0.235 0.064 1.025311e-82 CTL_MUT
## Sgms1 4.763037e-86 -2.0380562 0.265 0.083 1.428911e-82 CTL_MUT
## Gm43066 4.912951e-86 -4.0979924 0.244 0.005 1.473885e-82 CTL_MUT
## Unc93b1 6.222110e-86 -1.4497825 0.106 0.015 1.866633e-82 CTL_MUT
## Glud1 6.897636e-86 -0.4857885 0.257 0.167 2.069291e-82 CTL_MUT
## Gal 1.367556e-85 -4.1345588 0.156 0.037 4.102668e-82 CTL_MUT
## Cck 1.379929e-85 -3.3965767 0.314 0.443 4.139787e-82 CTL_MUT
## Angptl4 1.464155e-85 -2.7008171 0.151 0.010 4.392465e-82 CTL_MUT
## Bcam 1.792291e-85 -1.8883390 0.174 0.020 5.376874e-82 CTL_MUT
## Clic5 2.399574e-85 -2.9868465 0.165 0.022 7.198722e-82 CTL_MUT
## Neat1 2.898026e-85 -0.9323816 0.176 0.125 8.694078e-82 CTL_MUT
## Sox3 3.235774e-85 -4.5038669 0.158 0.006 9.707323e-82 CTL_MUT
## Ctsz 3.496923e-85 -4.3030427 0.237 0.111 1.049077e-81 CTL_MUT
## Slc30a3 5.004907e-85 1.7092115 0.264 0.184 1.501472e-81 CTL_MUT
## Atp2a3 5.171922e-85 0.3253822 0.115 0.006 1.551577e-81 CTL_MUT
## Carmil1 5.262737e-85 2.5404285 0.219 0.055 1.578821e-81 CTL_MUT
## Rhoc 5.997896e-85 -1.6466503 0.181 0.054 1.799369e-81 CTL_MUT
## Gper1 7.885797e-85 -2.7803396 0.100 0.015 2.365739e-81 CTL_MUT
## Itpripl2 8.823231e-85 -2.4259323 0.169 0.009 2.646969e-81 CTL_MUT
## Epb41l4a 1.040222e-84 -1.5567398 0.206 0.014 3.120665e-81 CTL_MUT
## Epas1 1.236823e-84 -2.3759662 0.145 0.068 3.710469e-81 CTL_MUT
## Tcim 1.800811e-84 -3.4929283 0.151 0.008 5.402433e-81 CTL_MUT
## Pdgfb 3.026534e-84 -5.0723191 0.218 0.067 9.079602e-81 CTL_MUT
## Zc3hav1 5.846929e-84 -4.0281772 0.162 0.004 1.754079e-80 CTL_MUT
## Abcg2 5.904989e-84 -2.7426204 0.209 0.072 1.771497e-80 CTL_MUT
## Nrep 1.085665e-83 -2.5273776 0.239 0.088 3.256995e-80 CTL_MUT
## Anxa3 1.718229e-83 -2.6397826 0.151 0.024 5.154688e-80 CTL_MUT
## Hist1h1b 2.358304e-83 -3.7670717 0.118 0.020 7.074913e-80 CTL_MUT
## Acvrl1 3.862607e-83 -1.9579870 0.148 0.022 1.158782e-79 CTL_MUT
## Scarf2 9.640671e-83 -5.1494871 0.158 0.021 2.892201e-79 CTL_MUT
## Sema3c 1.337076e-82 -2.6958425 0.163 0.045 4.011229e-79 CTL_MUT
## Csrp1 3.272025e-82 -2.0721691 0.126 0.077 9.816074e-79 CTL_MUT
## Cntn2 4.239777e-82 -2.8149283 0.285 0.074 1.271933e-78 CTL_MUT
## Myo1e 5.385538e-82 -3.4432945 0.154 0.043 1.615662e-78 CTL_MUT
## Tgfbr2 5.782473e-82 -1.7015244 0.134 0.019 1.734742e-78 CTL_MUT
## Degs2 1.002254e-81 -1.2553101 0.140 0.015 3.006763e-78 CTL_MUT
## Acer2 1.850252e-81 -3.4146371 0.184 0.013 5.550755e-78 CTL_MUT
## St8sia6 2.200352e-81 -3.6704534 0.217 0.007 6.601057e-78 CTL_MUT
## Asrgl1 6.915094e-81 -1.5277192 0.246 0.146 2.074528e-77 CTL_MUT
## Cemip2 7.505502e-81 -4.8808614 0.243 0.046 2.251651e-77 CTL_MUT
## Tcap 9.069395e-81 -3.6960339 0.160 0.083 2.720818e-77 CTL_MUT
## Pld2 9.348064e-81 -3.4997763 0.208 0.014 2.804419e-77 CTL_MUT
## Col18a1 1.105049e-80 -4.4086330 0.208 0.004 3.315146e-77 CTL_MUT
## Colec12 1.361244e-80 1.2266500 0.124 0.012 4.083733e-77 CTL_MUT
## Hmmr 2.212043e-80 -2.9691396 0.132 0.010 6.636130e-77 CTL_MUT
## Rnf213 2.801248e-80 -0.9369430 0.170 0.010 8.403744e-77 CTL_MUT
## Itprip 3.315956e-80 -3.5072187 0.187 0.003 9.947869e-77 CTL_MUT
## Tap2 4.866973e-80 -3.5688997 0.155 0.013 1.460092e-76 CTL_MUT
## Msi2 1.094985e-79 -2.9018492 0.275 0.133 3.284956e-76 CTL_MUT
## Utp14b 1.307097e-79 -2.4266104 0.178 0.075 3.921291e-76 CTL_MUT
## 4930523C07Rik 1.350863e-79 -1.9685650 0.151 0.018 4.052590e-76 CTL_MUT
## Fezf2 1.412942e-79 -2.1817161 0.215 0.100 4.238825e-76 CTL_MUT
## Atp10a 1.695927e-79 -1.7641366 0.108 0.017 5.087780e-76 CTL_MUT
## Otud7b 2.221615e-79 -2.5740819 0.225 0.063 6.664845e-76 CTL_MUT
## Arhgap11a 2.258123e-79 -0.8998914 0.187 0.007 6.774369e-76 CTL_MUT
## Txnip 3.093359e-79 -1.9254460 0.147 0.023 9.280077e-76 CTL_MUT
## Pde1c 4.125987e-79 -4.0363372 0.129 0.031 1.237796e-75 CTL_MUT
## Kif20a 5.409009e-79 -4.6305838 0.189 0.003 1.622703e-75 CTL_MUT
## Npnt 7.375222e-79 -3.4919464 0.196 0.082 2.212567e-75 CTL_MUT
## Cks1b 9.586330e-79 0.9175796 0.141 0.017 2.875899e-75 CTL_MUT
## Dlx1 1.725003e-78 -1.6973613 0.119 0.061 5.175010e-75 CTL_MUT
## Fas 2.491407e-78 -2.9242097 0.164 0.006 7.474220e-75 CTL_MUT
## Itpkb 4.810426e-78 -1.0614813 0.154 0.038 1.443128e-74 CTL_MUT
## Brca1 5.787312e-78 -4.2044593 0.181 0.017 1.736194e-74 CTL_MUT
## Dcx 7.670602e-78 -0.7870991 0.261 0.111 2.301181e-74 CTL_MUT
## Cd38 1.076695e-77 -2.3387343 0.146 0.008 3.230086e-74 CTL_MUT
## Bmp7 1.077691e-77 -3.6325962 0.110 0.008 3.233074e-74 CTL_MUT
## Ocln 3.504102e-77 -3.2922605 0.159 0.009 1.051230e-73 CTL_MUT
## Lamc1 4.159786e-77 0.5736534 0.197 0.040 1.247936e-73 CTL_MUT
## Tns1 5.464813e-77 -0.8803523 0.170 0.041 1.639444e-73 CTL_MUT
## Clu 5.751425e-77 -1.6553038 0.202 0.314 1.725427e-73 CTL_MUT
## Hbegf 6.087549e-77 -4.0550878 0.162 0.049 1.826265e-73 CTL_MUT
## Rxfp1 6.488678e-77 -3.1798974 0.230 0.036 1.946604e-73 CTL_MUT
## Kif11 7.896689e-77 -4.0220777 0.153 0.005 2.369007e-73 CTL_MUT
## Cpne9 2.121310e-76 -2.2319686 0.213 0.087 6.363931e-73 CTL_MUT
## Elk3 2.161643e-76 -1.6604845 0.208 0.030 6.484929e-73 CTL_MUT
## Rorb 2.576028e-76 1.1905914 0.218 0.169 7.728084e-73 CTL_MUT
## Cd59a 2.953748e-76 -2.9147348 0.189 0.052 8.861243e-73 CTL_MUT
## Spats2l 3.104744e-76 -1.3874786 0.249 0.120 9.314233e-73 CTL_MUT
## Enpp2 3.594302e-76 -3.4664362 0.256 0.204 1.078291e-72 CTL_MUT
## Gfra1 3.972684e-76 -2.6981170 0.147 0.033 1.191805e-72 CTL_MUT
## Rnf152 4.092432e-76 -3.2314553 0.194 0.049 1.227730e-72 CTL_MUT
## Tmem123 4.112566e-76 -3.4582888 0.160 0.015 1.233770e-72 CTL_MUT
## Tmem255b 7.591010e-76 -5.6874287 0.103 0.018 2.277303e-72 CTL_MUT
## Tnfrsf1a 9.487759e-76 -2.6918001 0.193 0.014 2.846328e-72 CTL_MUT
## Dlx5 9.875718e-76 -3.4949821 0.127 0.025 2.962715e-72 CTL_MUT
## Amotl1 1.092936e-75 -2.0352568 0.204 0.045 3.278808e-72 CTL_MUT
## Cd151 1.094750e-75 -1.7068553 0.207 0.054 3.284251e-72 CTL_MUT
## Peg10 1.221682e-75 -3.4982936 0.186 0.013 3.665047e-72 CTL_MUT
## Slc16a9 1.323791e-75 0.8483530 0.144 0.010 3.971372e-72 CTL_MUT
## Ltbp1 1.486915e-75 -3.4958014 0.193 0.008 4.460744e-72 CTL_MUT
## Tax1bp3 2.294088e-75 -4.6404880 0.182 0.022 6.882265e-72 CTL_MUT
## Malt1 2.448677e-75 -3.6836997 0.192 0.032 7.346031e-72 CTL_MUT
## Gm20342 3.033204e-75 -1.6256203 0.224 0.038 9.099613e-72 CTL_MUT
## Dio3 3.371043e-75 -5.4012649 0.179 0.006 1.011313e-71 CTL_MUT
## Ltbp4 4.088608e-75 -3.3384665 0.180 0.040 1.226583e-71 CTL_MUT
## Neb 4.864682e-75 -4.7970297 0.209 0.008 1.459405e-71 CTL_MUT
## Sox13 6.229175e-75 -3.2944614 0.177 0.005 1.868752e-71 CTL_MUT
## Mirg 2.507098e-74 -2.4441240 0.257 0.073 7.521293e-71 CTL_MUT
## Rsad2 4.237401e-74 -5.0635283 0.169 0.005 1.271220e-70 CTL_MUT
## Fibcd1 8.512686e-74 -3.3142200 0.188 0.023 2.553806e-70 CTL_MUT
## Fbxo30 9.211155e-74 -4.3665570 0.198 0.017 2.763347e-70 CTL_MUT
## Elf1 9.367802e-74 -2.7651659 0.147 0.023 2.810340e-70 CTL_MUT
## Slfn2 1.021934e-73 -3.9115764 0.134 0.012 3.065802e-70 CTL_MUT
## Ggt5 1.105991e-73 -1.2867181 0.107 0.008 3.317973e-70 CTL_MUT
## Fchsd2 1.271725e-73 -0.9120893 0.240 0.072 3.815176e-70 CTL_MUT
## Abhd2 1.582992e-73 1.0482084 0.245 0.092 4.748976e-70 CTL_MUT
## Necab2 1.611053e-73 -0.6186369 0.215 0.073 4.833159e-70 CTL_MUT
## Cdc42ep5 2.764592e-73 -4.0425262 0.165 0.008 8.293776e-70 CTL_MUT
## Ezh2 2.917297e-73 -2.2568977 0.152 0.028 8.751892e-70 CTL_MUT
## Tgif1 3.125213e-73 -3.8300440 0.120 0.010 9.375640e-70 CTL_MUT
## F11r 3.739264e-73 -2.3005094 0.128 0.015 1.121779e-69 CTL_MUT
## Pld1 4.481555e-73 -1.9182016 0.136 0.027 1.344466e-69 CTL_MUT
## Lig1 6.573152e-73 -2.7526290 0.194 0.035 1.971946e-69 CTL_MUT
## Lamp5 1.002735e-72 1.9726167 0.246 0.285 3.008206e-69 CTL_MUT
## Bach1 1.149589e-72 -2.9439437 0.197 0.050 3.448768e-69 CTL_MUT
## Chrm2 1.448386e-72 -4.8796878 0.217 0.046 4.345157e-69 CTL_MUT
## Hcn2 1.598638e-72 -0.5718387 0.259 0.106 4.795915e-69 CTL_MUT
## Hells 2.051427e-72 -4.4180640 0.223 0.008 6.154282e-69 CTL_MUT
## Gbp9 4.170358e-72 -4.0710387 0.189 0.010 1.251107e-68 CTL_MUT
## Tns3 4.561486e-72 -3.8985674 0.115 0.030 1.368446e-68 CTL_MUT
## Wnt5a 7.552621e-72 -3.1574149 0.143 0.011 2.265786e-68 CTL_MUT
## Gm38039 9.304908e-72 -5.7994069 0.175 0.008 2.791473e-68 CTL_MUT
## Tgfb1 1.009600e-71 -3.5304732 0.105 0.020 3.028801e-68 CTL_MUT
## Slc40a1 1.115749e-71 -2.1379743 0.113 0.024 3.347246e-68 CTL_MUT
## Calca 1.270059e-71 -4.7941232 0.189 0.022 3.810176e-68 CTL_MUT
## Map3k20 1.542172e-71 -1.8374150 0.158 0.025 4.626515e-68 CTL_MUT
## Afap1l2 1.873423e-71 -2.2329816 0.157 0.045 5.620268e-68 CTL_MUT
## Npy2r 1.893599e-71 -5.0549716 0.139 0.050 5.680798e-68 CTL_MUT
## Gm20109 1.978566e-71 -4.3193725 0.166 0.018 5.935697e-68 CTL_MUT
## Mmd2 3.771634e-71 -1.6935206 0.251 0.132 1.131490e-67 CTL_MUT
## Cacng4 5.778543e-71 -2.3683370 0.165 0.063 1.733563e-67 CTL_MUT
## Clrn1 6.167069e-71 -3.9956728 0.227 0.003 1.850121e-67 CTL_MUT
## Mtus1 8.212626e-71 -2.4221408 0.197 0.035 2.463788e-67 CTL_MUT
## Mfng 8.434157e-71 -2.9054048 0.153 0.006 2.530247e-67 CTL_MUT
## Mcc 1.026961e-70 -1.9164892 0.187 0.033 3.080883e-67 CTL_MUT
## Orai1 1.219874e-70 -2.3494038 0.175 0.062 3.659623e-67 CTL_MUT
## C730034F03Rik 1.469167e-70 -2.8024454 0.236 0.019 4.407500e-67 CTL_MUT
## Sncaip 1.796355e-70 -3.0399122 0.221 0.010 5.389066e-67 CTL_MUT
## Flnb 3.886444e-70 -2.2020046 0.210 0.027 1.165933e-66 CTL_MUT
## B230216N24Rik 3.890167e-70 -2.3297431 0.249 0.115 1.167050e-66 CTL_MUT
## Klf11 4.840726e-70 -1.9530583 0.237 0.013 1.452218e-66 CTL_MUT
## Paqr5 5.183831e-70 0.6629631 0.143 0.019 1.555149e-66 CTL_MUT
## Pcdh8 5.273435e-70 -2.6536859 0.207 0.058 1.582030e-66 CTL_MUT
## Tent5c 5.294071e-70 -1.1958366 0.101 0.016 1.588221e-66 CTL_MUT
## Birc5 7.553695e-70 -1.3404622 0.185 0.007 2.266108e-66 CTL_MUT
## Rdm1 1.332218e-69 -2.7252284 0.171 0.012 3.996653e-66 CTL_MUT
## Card10 1.468183e-69 -4.0123963 0.213 0.006 4.404548e-66 CTL_MUT
## Arl4c 1.618361e-69 0.3080398 0.202 0.093 4.855084e-66 CTL_MUT
## Slc16a12 1.814992e-69 -2.9087779 0.133 0.028 5.444976e-66 CTL_MUT
## Sirt2 2.679598e-69 -2.9505124 0.241 0.162 8.038794e-66 CTL_MUT
## Cdca3 2.960170e-69 -1.2185313 0.150 0.009 8.880509e-66 CTL_MUT
## Gpc6 3.156413e-69 1.9924826 0.251 0.092 9.469239e-66 CTL_MUT
## Mindy1 3.503063e-69 -2.9377731 0.226 0.050 1.050919e-65 CTL_MUT
## Gm42047 3.826000e-69 -4.2798656 0.171 0.046 1.147800e-65 CTL_MUT
## Maff 3.864373e-69 -2.9954154 0.148 0.007 1.159312e-65 CTL_MUT
## Vegfa 5.350731e-69 -2.4880879 0.159 0.053 1.605219e-65 CTL_MUT
## Prdm1 5.945786e-69 -4.0309086 0.182 0.005 1.783736e-65 CTL_MUT
## Wwtr1 9.450450e-69 -0.7152568 0.168 0.024 2.835135e-65 CTL_MUT
## Mmrn2 1.070277e-68 -1.6142701 0.120 0.011 3.210832e-65 CTL_MUT
## Ntng1 1.181260e-68 -5.8593572 0.239 0.106 3.543781e-65 CTL_MUT
## Sgo2a 1.325385e-68 -2.9336459 0.150 0.005 3.976155e-65 CTL_MUT
## Cpne7 1.576382e-68 -2.1176747 0.222 0.058 4.729145e-65 CTL_MUT
## Nppa 2.207833e-68 -4.9005769 0.149 0.008 6.623498e-65 CTL_MUT
## Erbin 2.219863e-68 -3.5966078 0.238 0.045 6.659590e-65 CTL_MUT
## Ubash3b 3.153228e-68 -1.0599728 0.228 0.061 9.459683e-65 CTL_MUT
## Cd248 3.348009e-68 -0.3605108 0.182 0.010 1.004403e-64 CTL_MUT
## Lima1 3.548357e-68 -3.2019897 0.178 0.044 1.064507e-64 CTL_MUT
## Palmd 3.777247e-68 -4.1244412 0.240 0.104 1.133174e-64 CTL_MUT
## Tap1 3.983727e-68 -4.4361045 0.152 0.005 1.195118e-64 CTL_MUT
## Slc12a2 6.432441e-68 -0.6527978 0.221 0.078 1.929732e-64 CTL_MUT
## Serinc5 6.865911e-68 -2.5895322 0.224 0.047 2.059773e-64 CTL_MUT
## Pgm5 8.302538e-68 -2.5259177 0.176 0.011 2.490761e-64 CTL_MUT
## Lyl1 8.831722e-68 -4.1535130 0.143 0.026 2.649517e-64 CTL_MUT
## C130071C03Rik 9.504142e-68 -3.6524901 0.266 0.105 2.851242e-64 CTL_MUT
## Slc22a8 1.413382e-67 -2.2608181 0.137 0.025 4.240145e-64 CTL_MUT
## Grip1 2.513916e-67 -3.8571310 0.241 0.080 7.541749e-64 CTL_MUT
## Zfp469 3.112627e-67 -3.1325184 0.155 0.025 9.337881e-64 CTL_MUT
## Ifi35 3.381695e-67 -2.7866072 0.120 0.013 1.014509e-63 CTL_MUT
## Yes1 4.639700e-67 -0.9249512 0.216 0.022 1.391910e-63 CTL_MUT
## Trp53inp1 5.236873e-67 -2.9366007 0.211 0.023 1.571062e-63 CTL_MUT
## Bnip2 6.256522e-67 -2.2326897 0.263 0.094 1.876957e-63 CTL_MUT
## Rrad 8.749246e-67 -3.0908419 0.152 0.025 2.624774e-63 CTL_MUT
## Fibin 8.832576e-67 -4.3971166 0.227 0.007 2.649773e-63 CTL_MUT
## S100a6 9.580068e-67 -2.4676946 0.185 0.087 2.874020e-63 CTL_MUT
## Sema5a 1.771025e-66 -1.6039366 0.247 0.074 5.313076e-63 CTL_MUT
## Gm31305 1.811910e-66 -3.3751113 0.177 0.010 5.435729e-63 CTL_MUT
## Mcm3 2.247614e-66 -3.3444648 0.160 0.017 6.742843e-63 CTL_MUT
## Tppp3 2.557211e-66 -2.8145293 0.229 0.099 7.671633e-63 CTL_MUT
## Isyna1 2.805217e-66 -1.7868021 0.217 0.064 8.415651e-63 CTL_MUT
## Pde5a 3.335916e-66 -2.3556698 0.193 0.016 1.000775e-62 CTL_MUT
## Rcn3 3.346010e-66 -0.5901560 0.144 0.009 1.003803e-62 CTL_MUT
## Msn 5.087562e-66 -2.0622703 0.134 0.044 1.526269e-62 CTL_MUT
## Zfpm2 5.757216e-66 -0.6606898 0.231 0.031 1.727165e-62 CTL_MUT
## Sema4d 6.218156e-66 -3.3309735 0.253 0.093 1.865447e-62 CTL_MUT
## Slc17a8 6.528968e-66 -3.9341444 0.158 0.010 1.958690e-62 CTL_MUT
## 4931406P16Rik 6.608678e-66 -0.9459437 0.229 0.073 1.982603e-62 CTL_MUT
## Crlf3 6.669224e-66 -3.3177762 0.181 0.033 2.000767e-62 CTL_MUT
## Ecm2 8.426961e-66 -1.0474156 0.153 0.027 2.528088e-62 CTL_MUT
## Pdlim5 1.134395e-65 -3.3237116 0.164 0.029 3.403185e-62 CTL_MUT
## Entpd1 1.172204e-65 -0.9302660 0.122 0.030 3.516613e-62 CTL_MUT
## Mgat4c 1.318000e-65 -1.5950327 0.254 0.102 3.954000e-62 CTL_MUT
## Acsl6 2.048766e-65 -0.7173385 0.228 0.115 6.146298e-62 CTL_MUT
## Lgmn 2.422702e-65 -3.1934360 0.224 0.091 7.268107e-62 CTL_MUT
## Cpt1a 3.769780e-65 -2.2463184 0.162 0.021 1.130934e-61 CTL_MUT
## Cacna2d3 3.957297e-65 -0.2675056 0.301 0.127 1.187189e-61 CTL_MUT
## Rhbdf1 4.805645e-65 -4.1806050 0.220 0.010 1.441693e-61 CTL_MUT
## Rgs12 6.150338e-65 -2.8636775 0.252 0.083 1.845101e-61 CTL_MUT
## Pttg1ip 9.208148e-65 0.6291566 0.256 0.090 2.762444e-61 CTL_MUT
## Phldb2 9.493186e-65 -1.4893797 0.141 0.013 2.847956e-61 CTL_MUT
## Thbs2 1.015566e-64 -4.9283389 0.181 0.005 3.046698e-61 CTL_MUT
## Apbb1ip 1.542041e-64 -2.5095643 0.125 0.030 4.626122e-61 CTL_MUT
## Epb41l2 1.555779e-64 -1.8913887 0.198 0.097 4.667337e-61 CTL_MUT
## Lypd6 2.024242e-64 -4.2003818 0.180 0.030 6.072727e-61 CTL_MUT
## Ebf1 2.412760e-64 -0.5441533 0.153 0.020 7.238280e-61 CTL_MUT
## Crtac1 2.441481e-64 -2.9512375 0.226 0.098 7.324444e-61 CTL_MUT
## St6galnac5 2.464892e-64 2.9800398 0.278 0.139 7.394675e-61 CTL_MUT
## Esyt1 2.786334e-64 -3.0382356 0.205 0.008 8.359002e-61 CTL_MUT
## Heg1 2.893589e-64 -1.6907908 0.176 0.039 8.680766e-61 CTL_MUT
## Cnr1 8.087572e-64 -3.1626930 0.262 0.214 2.426272e-60 CTL_MUT
## Sag 1.084191e-63 -8.2331817 0.248 0.010 3.252574e-60 CTL_MUT
## Gm3764 1.190339e-63 -1.7405274 0.275 0.158 3.571018e-60 CTL_MUT
## Arhgap18 1.800045e-63 -3.1691733 0.165 0.017 5.400134e-60 CTL_MUT
## Slc20a1 1.875811e-63 -2.7169079 0.299 0.109 5.627432e-60 CTL_MUT
## Lair1 2.117346e-63 -3.3956311 0.153 0.013 6.352039e-60 CTL_MUT
## Fn1 2.801937e-63 -0.7405700 0.147 0.030 8.405810e-60 CTL_MUT
## Zbtb20 5.982627e-63 -1.8212815 0.270 0.227 1.794788e-59 CTL_MUT
## Itm2a 6.610433e-63 -1.7891322 0.169 0.080 1.983130e-59 CTL_MUT
## Fads1 9.276268e-63 -2.1798929 0.272 0.099 2.782880e-59 CTL_MUT
## Sccpdh 1.097376e-62 0.2931706 0.227 0.146 3.292127e-59 CTL_MUT
## Plod2 1.474796e-62 -2.4827029 0.215 0.015 4.424389e-59 CTL_MUT
## Hrh3 2.019483e-62 1.7532147 0.257 0.104 6.058450e-59 CTL_MUT
## P2rx1 2.473588e-62 -3.7019152 0.134 0.040 7.420763e-59 CTL_MUT
## Inpp5j 3.058800e-62 -4.8387695 0.219 0.058 9.176400e-59 CTL_MUT
## Prss23 3.174104e-62 -2.7246379 0.193 0.059 9.522312e-59 CTL_MUT
## Timp3 4.220378e-62 -3.0303991 0.181 0.081 1.266113e-58 CTL_MUT
## A330076H08Rik 4.320585e-62 -1.0460026 0.258 0.086 1.296175e-58 CTL_MUT
## Spsb4 4.353423e-62 -3.3328663 0.206 0.018 1.306027e-58 CTL_MUT
## Mmp15 5.291131e-62 -2.3156936 0.234 0.023 1.587339e-58 CTL_MUT
## Fmnl3 5.748562e-62 -3.4259404 0.157 0.022 1.724569e-58 CTL_MUT
## H2-D1 6.444398e-62 -1.2843165 0.182 0.062 1.933319e-58 CTL_MUT
## Tagln2 1.196158e-61 -1.4692633 0.173 0.047 3.588475e-58 CTL_MUT
## Jag1 1.371114e-61 -3.5187385 0.199 0.005 4.113343e-58 CTL_MUT
## Vasp 1.669836e-61 -3.1653892 0.193 0.016 5.009509e-58 CTL_MUT
## Gm47591 1.793647e-61 1.1117625 0.250 0.085 5.380940e-58 CTL_MUT
## Col25a1 2.517323e-61 -4.6000413 0.224 0.072 7.551968e-58 CTL_MUT
## Lbh 3.162701e-61 -2.7807434 0.207 0.050 9.488103e-58 CTL_MUT
## Plat 3.714165e-61 -0.4192259 0.194 0.052 1.114250e-57 CTL_MUT
## Kif13b 4.053316e-61 -1.9580880 0.248 0.054 1.215995e-57 CTL_MUT
## Plpp4 5.159461e-61 -2.2563030 0.152 0.015 1.547838e-57 CTL_MUT
## Tiparp 6.102959e-61 -1.2305603 0.257 0.067 1.830888e-57 CTL_MUT
## Tafa1 7.681902e-61 0.8252899 0.261 0.181 2.304571e-57 CTL_MUT
## Bhlhe40 7.740256e-61 0.5607326 0.249 0.109 2.322077e-57 CTL_MUT
## Gas1 9.925989e-61 -2.8173587 0.157 0.025 2.977797e-57 CTL_MUT
## Bcl2l11 1.011238e-60 -4.1959555 0.226 0.021 3.033715e-57 CTL_MUT
## Fgd5 1.149975e-60 -1.1447935 0.151 0.010 3.449924e-57 CTL_MUT
## Smagp 1.221810e-60 -4.4655297 0.167 0.008 3.665430e-57 CTL_MUT
## Emx2 1.488983e-60 -1.7686649 0.117 0.028 4.466950e-57 CTL_MUT
## Fbxl7 2.026692e-60 -3.9887040 0.234 0.012 6.080076e-57 CTL_MUT
## Tpm4 3.948409e-60 -1.6994683 0.192 0.083 1.184523e-56 CTL_MUT
## Syt10 4.104570e-60 -9.6626375 0.194 0.036 1.231371e-56 CTL_MUT
## Nxn 4.412763e-60 -3.0655404 0.168 0.023 1.323829e-56 CTL_MUT
## Tmtc2 4.525757e-60 -2.3796315 0.229 0.023 1.357727e-56 CTL_MUT
## Igfbp7 4.871905e-60 1.1217580 0.181 0.065 1.461572e-56 CTL_MUT
## Lmo1 4.918745e-60 1.5599486 0.248 0.073 1.475623e-56 CTL_MUT
## Col12a1 5.762933e-60 -2.0471643 0.167 0.046 1.728880e-56 CTL_MUT
## Sp9 6.983777e-60 -3.1216103 0.112 0.028 2.095133e-56 CTL_MUT
## Aldh1a1 7.504877e-60 -3.9025063 0.220 0.023 2.251463e-56 CTL_MUT
## Hspa2 8.777717e-60 -3.1522749 0.233 0.113 2.633315e-56 CTL_MUT
## Irak2 9.509372e-60 -4.3751324 0.221 0.018 2.852812e-56 CTL_MUT
## Gm2a 1.087423e-59 -1.8101256 0.210 0.107 3.262268e-56 CTL_MUT
## Rasl10a 1.813781e-59 -0.9381348 0.271 0.132 5.441343e-56 CTL_MUT
## Pld5 2.927865e-59 -1.6510534 0.172 0.033 8.783594e-56 CTL_MUT
## Ampd3 4.352359e-59 -2.1199910 0.161 0.029 1.305708e-55 CTL_MUT
## Ppp1r15a 4.437479e-59 -3.4416683 0.255 0.077 1.331244e-55 CTL_MUT
## Socs3 6.077563e-59 -3.0262366 0.149 0.019 1.823269e-55 CTL_MUT
## Apold1 6.625639e-59 -1.4534032 0.159 0.060 1.987692e-55 CTL_MUT
## Rictor 6.663459e-59 -3.0778653 0.303 0.125 1.999038e-55 CTL_MUT
## Pcdh15 9.295693e-59 -1.7267033 0.204 0.072 2.788708e-55 CTL_MUT
## Rasd1 1.061232e-58 -3.2970024 0.202 0.027 3.183697e-55 CTL_MUT
## Prkd3 1.485511e-58 -2.0641528 0.211 0.020 4.456533e-55 CTL_MUT
## Eng 7.401639e-58 -1.3509597 0.158 0.035 2.220492e-54 CTL_MUT
## Prom1 7.452117e-58 -1.9233716 0.164 0.025 2.235635e-54 CTL_MUT
## Stom 1.231857e-57 -2.8669378 0.165 0.009 3.695572e-54 CTL_MUT
## Kif23 1.369195e-57 -1.9823106 0.179 0.009 4.107586e-54 CTL_MUT
## Spc24 1.535982e-57 -0.7310801 0.218 0.018 4.607945e-54 CTL_MUT
## Cpne3 2.322518e-57 -0.8705642 0.238 0.031 6.967554e-54 CTL_MUT
## Abat 3.127689e-57 -5.2940843 0.229 0.119 9.383068e-54 CTL_MUT
## Ddc 4.064351e-57 -2.2043503 0.154 0.013 1.219305e-53 CTL_MUT
## Cox6b2 4.112513e-57 -3.7094820 0.204 0.006 1.233754e-53 CTL_MUT
## Ccnd1 4.478465e-57 -3.6208042 0.204 0.121 1.343539e-53 CTL_MUT
## Nefh 8.359189e-57 -2.8475491 0.212 0.088 2.507757e-53 CTL_MUT
## Ckap2 1.487186e-56 -5.5913250 0.187 0.004 4.461557e-53 CTL_MUT
## Ucp2 1.979855e-56 -1.5549585 0.161 0.057 5.939565e-53 CTL_MUT
## Cartpt 2.031538e-56 -2.0578630 0.144 0.045 6.094613e-53 CTL_MUT
## Gpr146 2.265758e-56 -0.4682448 0.164 0.038 6.797274e-53 CTL_MUT
## Unc5c 3.938020e-56 2.7890866 0.266 0.093 1.181406e-52 CTL_MUT
## Zmat4 4.070313e-56 1.3067917 0.237 0.098 1.221094e-52 CTL_MUT
## Mpp7 9.199607e-56 -2.4247288 0.270 0.047 2.759882e-52 CTL_MUT
## Rnf125 1.186943e-55 -4.9943767 0.118 0.008 3.560829e-52 CTL_MUT
## Git2 1.320251e-55 -1.1843444 0.244 0.096 3.960752e-52 CTL_MUT
## Smco4 1.720320e-55 -2.7315325 0.178 0.019 5.160960e-52 CTL_MUT
## Cxcl12 1.926153e-55 -2.2974348 0.208 0.077 5.778460e-52 CTL_MUT
## Fbln2 2.334181e-55 -4.1595032 0.226 0.013 7.002543e-52 CTL_MUT
## Crip1 3.454980e-55 -2.2210497 0.167 0.035 1.036494e-51 CTL_MUT
## Lgi3 4.851038e-55 0.7474488 0.273 0.122 1.455312e-51 CTL_MUT
## Isoc1 5.075610e-55 -5.5567657 0.198 0.080 1.522683e-51 CTL_MUT
## Gm10862 5.155577e-55 -1.0013832 0.234 0.055 1.546673e-51 CTL_MUT
## Klf2 5.509022e-55 -1.5372066 0.158 0.086 1.652707e-51 CTL_MUT
## Airn 9.730577e-55 -1.1748675 0.207 0.008 2.919173e-51 CTL_MUT
## Utrn 1.848483e-54 -2.0236630 0.171 0.072 5.545449e-51 CTL_MUT
## Nnat 4.181303e-54 -2.8944122 0.261 0.153 1.254391e-50 CTL_MUT
## Rasip1 5.118870e-54 -0.9098401 0.198 0.037 1.535661e-50 CTL_MUT
## Fgd6 6.805372e-54 -4.1444625 0.223 0.020 2.041612e-50 CTL_MUT
## Trerf1 7.395989e-54 -3.2643356 0.276 0.086 2.218797e-50 CTL_MUT
## Nr2f2 8.851933e-54 -0.9112084 0.159 0.025 2.655580e-50 CTL_MUT
## Phldb1 1.217194e-53 -3.0546660 0.198 0.042 3.651581e-50 CTL_MUT
## Atp6v0e 1.319180e-53 -0.2654198 0.248 0.118 3.957540e-50 CTL_MUT
## Gm19938 1.336152e-53 -2.2702165 0.272 0.064 4.008455e-50 CTL_MUT
## Thrsp 1.493976e-53 -2.4902850 0.205 0.120 4.481929e-50 CTL_MUT
## Col4a1 1.612532e-53 -0.5427009 0.204 0.068 4.837596e-50 CTL_MUT
## Ddit4 1.848718e-53 -2.6432344 0.278 0.080 5.546153e-50 CTL_MUT
## Actb 3.588435e-53 3.0443617 0.350 0.453 1.076531e-49 CTL_MUT
## Abcc9 5.215009e-53 1.8683371 0.172 0.020 1.564503e-49 CTL_MUT
## Idi1 5.748453e-53 -2.8610561 0.236 0.105 1.724536e-49 CTL_MUT
## Slc19a1 6.655140e-53 -1.3768632 0.165 0.027 1.996542e-49 CTL_MUT
## 2900052L18Rik 8.277397e-53 -0.8332199 0.250 0.048 2.483219e-49 CTL_MUT
## Lama4 1.201361e-52 -2.5915244 0.179 0.016 3.604082e-49 CTL_MUT
## Insig1 1.933280e-52 0.8944995 0.204 0.094 5.799839e-49 CTL_MUT
## Ifnar2 3.194388e-52 1.4317701 0.263 0.088 9.583165e-49 CTL_MUT
## Traf4 7.168828e-52 -5.1961591 0.207 0.020 2.150648e-48 CTL_MUT
## Nectin3 7.620079e-52 -4.2273549 0.201 0.096 2.286024e-48 CTL_MUT
## Gm4258 1.026348e-51 1.6730488 0.297 0.091 3.079044e-48 CTL_MUT
## Tjp2 1.497423e-51 -2.6647644 0.194 0.027 4.492268e-48 CTL_MUT
## Rskr 3.119231e-51 -3.6935861 0.228 0.048 9.357692e-48 CTL_MUT
## Foxn3 3.426668e-51 -0.6444752 0.275 0.123 1.028000e-47 CTL_MUT
## Rassf8 4.281697e-51 -2.8104839 0.210 0.020 1.284509e-47 CTL_MUT
## Pcdhgc3 1.405444e-50 -2.6151846 0.152 0.022 4.216331e-47 CTL_MUT
## Stk32a 1.769158e-50 -3.7638466 0.101 0.025 5.307475e-47 CTL_MUT
## Pou3f2 3.086082e-50 -1.4111744 0.231 0.120 9.258245e-47 CTL_MUT
## Grn 3.455359e-50 -6.2085323 0.254 0.108 1.036608e-46 CTL_MUT
## 4933433G15Rik 3.532859e-50 -4.3276537 0.185 0.025 1.059858e-46 CTL_MUT
## Tmc7 5.666960e-50 -2.8766057 0.204 0.029 1.700088e-46 CTL_MUT
## Proser2 7.342896e-50 -2.8695358 0.151 0.014 2.202869e-46 CTL_MUT
## Grrp1 1.050581e-49 -3.1517283 0.160 0.011 3.151744e-46 CTL_MUT
## Arhgap5 1.062453e-49 4.1683169 0.324 0.235 3.187358e-46 CTL_MUT
## Sulf2 1.067938e-49 0.4736869 0.281 0.131 3.203815e-46 CTL_MUT
## Rasgrp3 1.302404e-49 -5.4136574 0.139 0.020 3.907212e-46 CTL_MUT
## Nr4a2 3.032018e-49 -1.5885856 0.236 0.067 9.096054e-46 CTL_MUT
## mt-Co3 3.927836e-49 0.4656797 0.594 0.504 1.178351e-45 CTL_MUT
## Rrbp1 4.087683e-49 -2.8196560 0.293 0.184 1.226305e-45 CTL_MUT
## Rbms1 4.771555e-49 -4.6421533 0.239 0.061 1.431467e-45 CTL_MUT
## Aldh1l1 6.413222e-49 -2.6961641 0.151 0.072 1.923967e-45 CTL_MUT
## Egfl8 6.551252e-49 -4.6544479 0.235 0.005 1.965376e-45 CTL_MUT
## Npc2 7.621033e-49 -3.9591589 0.264 0.128 2.286310e-45 CTL_MUT
## Slc16a1 1.092540e-48 -4.4472943 0.210 0.058 3.277620e-45 CTL_MUT
## Lcorl 1.123629e-48 -2.4288194 0.289 0.095 3.370887e-45 CTL_MUT
## Rbpms 1.195095e-48 -2.2487607 0.131 0.024 3.585285e-45 CTL_MUT
## Gm13889 1.201913e-48 -1.3011564 0.260 0.140 3.605740e-45 CTL_MUT
## Ddit4l 1.272178e-48 -2.0093205 0.207 0.067 3.816533e-45 CTL_MUT
## Zeb1 1.315901e-48 -1.4953473 0.262 0.106 3.947702e-45 CTL_MUT
## 1700017B05Rik 1.520869e-48 -3.1114818 0.188 0.023 4.562606e-45 CTL_MUT
## Ppp1r18 1.721182e-48 -1.6018807 0.154 0.026 5.163547e-45 CTL_MUT
## Yjefn3 4.131844e-48 -4.7383701 0.233 0.079 1.239553e-44 CTL_MUT
## Ppia 4.511273e-48 -0.3575013 0.376 0.461 1.353382e-44 CTL_MUT
## Nrp2 4.839379e-48 0.6186849 0.290 0.068 1.451814e-44 CTL_MUT
## Uaca 5.401365e-48 -0.8332309 0.143 0.019 1.620410e-44 CTL_MUT
## Cadps2 7.068327e-48 -4.7122778 0.247 0.131 2.120498e-44 CTL_MUT
## Smad7 7.113453e-48 0.4521263 0.289 0.111 2.134036e-44 CTL_MUT
## Triobp 7.622175e-48 -1.6967631 0.200 0.019 2.286653e-44 CTL_MUT
## Dgkb 1.513851e-47 0.6001248 0.278 0.221 4.541554e-44 CTL_MUT
## Ifitm2 2.814246e-47 -2.2527104 0.176 0.045 8.442738e-44 CTL_MUT
## Slc30a1 3.288496e-47 -0.6336416 0.251 0.093 9.865488e-44 CTL_MUT
## Wtip 6.136807e-47 -3.2893098 0.253 0.017 1.841042e-43 CTL_MUT
## Ttyh1 6.428877e-47 1.7721241 0.292 0.280 1.928663e-43 CTL_MUT
## Gamt 7.010431e-47 -3.2834035 0.185 0.078 2.103129e-43 CTL_MUT
## Vstm2l 7.510601e-47 1.5688373 0.249 0.170 2.253180e-43 CTL_MUT
## Cyfip1 7.583068e-47 -2.1039154 0.272 0.140 2.274920e-43 CTL_MUT
## Pycard 9.235531e-47 -1.0096695 0.241 0.017 2.770659e-43 CTL_MUT
## Vstm2a 2.957638e-46 -0.4909666 0.288 0.136 8.872914e-43 CTL_MUT
## Ehd2 4.500681e-46 -2.7832188 0.183 0.010 1.350204e-42 CTL_MUT
## Clec2d 5.661807e-46 -1.7362527 0.151 0.013 1.698542e-42 CTL_MUT
## Rnf121 6.890843e-46 -4.0801846 0.336 0.094 2.067253e-42 CTL_MUT
## Scube1 7.289909e-46 -5.0253068 0.223 0.078 2.186973e-42 CTL_MUT
## Ankrd44 1.178908e-45 -1.8292492 0.205 0.035 3.536724e-42 CTL_MUT
## Lars2 1.360550e-45 1.3821087 0.338 0.426 4.081649e-42 CTL_MUT
## Qdpr 2.003539e-45 -2.2606201 0.256 0.147 6.010618e-42 CTL_MUT
## Cast 2.689633e-45 -3.5008834 0.182 0.024 8.068899e-42 CTL_MUT
## Arhgdib 2.845575e-45 -1.3223895 0.144 0.030 8.536725e-42 CTL_MUT
## Wasf2 3.249727e-45 -1.6221000 0.190 0.065 9.749180e-42 CTL_MUT
## Adm 3.652590e-45 -3.4633086 0.168 0.037 1.095777e-41 CTL_MUT
## Nefm 6.438576e-45 -2.3075720 0.279 0.238 1.931573e-41 CTL_MUT
## Snrpn 6.559048e-45 -0.6782907 0.353 0.437 1.967714e-41 CTL_MUT
## Rasgrf2 1.580086e-44 1.6553111 0.276 0.126 4.740258e-41 CTL_MUT
## Dmrta2 1.673512e-44 -3.5399287 0.161 0.007 5.020535e-41 CTL_MUT
## Cotl1 2.302251e-44 -2.9320627 0.235 0.119 6.906752e-41 CTL_MUT
## Plcxd3 3.992017e-44 0.6277208 0.241 0.101 1.197605e-40 CTL_MUT
## Xylt1 4.839601e-44 2.4341570 0.288 0.107 1.451880e-40 CTL_MUT
## Ifitm3 5.007910e-44 -0.9117566 0.135 0.044 1.502373e-40 CTL_MUT
## Ets1 5.048034e-44 -1.0586877 0.159 0.026 1.514410e-40 CTL_MUT
## Olfm3 5.697239e-44 0.3672520 0.217 0.063 1.709172e-40 CTL_MUT
## Mt3 8.387992e-44 -1.8042969 0.318 0.376 2.516398e-40 CTL_MUT
## C1ql3 2.743711e-43 -2.9038671 0.340 0.392 8.231133e-40 CTL_MUT
## Pcp4l1 3.354437e-43 -1.5092263 0.198 0.117 1.006331e-39 CTL_MUT
## B2m 4.691278e-43 -3.4335617 0.223 0.088 1.407383e-39 CTL_MUT
## Bcl6b 4.871223e-43 -2.5315149 0.192 0.009 1.461367e-39 CTL_MUT
## Dner 5.160818e-43 -1.1280800 0.276 0.154 1.548246e-39 CTL_MUT
## Bmp2k 8.418261e-43 -2.1654300 0.159 0.040 2.525478e-39 CTL_MUT
## Urah 1.301771e-42 -2.6412345 0.207 0.009 3.905313e-39 CTL_MUT
## Sparcl1 1.319272e-42 -2.3961493 0.301 0.350 3.957816e-39 CTL_MUT
## Cyp51 1.992901e-42 0.3023952 0.307 0.160 5.978704e-39 CTL_MUT
## Mex3a 2.584286e-42 -1.9078734 0.190 0.016 7.752857e-39 CTL_MUT
## Nebl 2.763772e-42 3.0872017 0.291 0.109 8.291317e-39 CTL_MUT
## Samhd1 3.504148e-42 -3.6347116 0.229 0.030 1.051244e-38 CTL_MUT
## Tnnc1 3.644501e-42 -1.5576358 0.177 0.126 1.093350e-38 CTL_MUT
## Sema6d 5.427280e-42 -4.8142367 0.285 0.097 1.628184e-38 CTL_MUT
## Lsp1 6.879479e-42 -2.7496430 0.203 0.024 2.063844e-38 CTL_MUT
## Ppp1r14b 7.372348e-42 -1.6233422 0.234 0.138 2.211704e-38 CTL_MUT
## Gjc1 8.706438e-42 0.4909685 0.173 0.034 2.611931e-38 CTL_MUT
## A230057D06Rik 9.981988e-42 -1.8413347 0.254 0.063 2.994596e-38 CTL_MUT
## Grin3a 1.636913e-41 -2.1121939 0.220 0.081 4.910738e-38 CTL_MUT
## Cpox 2.638578e-41 -3.4417113 0.266 0.113 7.915733e-38 CTL_MUT
## Rcan1 2.885034e-41 -5.9563252 0.228 0.113 8.655103e-38 CTL_MUT
## Fjx1 3.168200e-41 -3.1729221 0.286 0.293 9.504601e-38 CTL_MUT
## Lypd1 3.736863e-41 -2.6846841 0.228 0.097 1.121059e-37 CTL_MUT
## Pantr1 4.978521e-41 2.7109958 0.282 0.209 1.493556e-37 CTL_MUT
## Tnxb 5.913244e-41 -3.2566218 0.159 0.019 1.773973e-37 CTL_MUT
## Slc17a6 7.589241e-41 -3.7917968 0.187 0.049 2.276772e-37 CTL_MUT
## Art3 7.601178e-41 4.6104641 0.110 0.031 2.280354e-37 CTL_MUT
## Slco3a1 1.063830e-40 2.2908937 0.313 0.104 3.191489e-37 CTL_MUT
## Rflna 1.211585e-40 -2.0264571 0.168 0.019 3.634755e-37 CTL_MUT
## Ccnt2 2.359288e-40 0.8329093 0.317 0.129 7.077863e-37 CTL_MUT
## Ckb 2.580326e-40 2.0121806 0.351 0.423 7.740978e-37 CTL_MUT
## Atp13a5 2.944402e-40 1.1506897 0.137 0.014 8.833205e-37 CTL_MUT
## Cd34 3.853286e-40 -3.5865084 0.248 0.104 1.155986e-36 CTL_MUT
## AU021092 5.163369e-40 -0.3074301 0.168 0.014 1.549011e-36 CTL_MUT
## Epb41 5.890303e-40 0.3651864 0.295 0.066 1.767091e-36 CTL_MUT
## Usp29 1.183268e-39 -2.0990298 0.303 0.118 3.549804e-36 CTL_MUT
## Clspn 1.536669e-39 -3.9212197 0.178 0.021 4.610008e-36 CTL_MUT
## Hip1 1.853375e-39 -0.9975024 0.258 0.116 5.560125e-36 CTL_MUT
## Adcyap1 1.941918e-39 -1.5108666 0.221 0.081 5.825755e-36 CTL_MUT
## Sorcs3 1.944687e-39 -1.7274022 0.269 0.129 5.834062e-36 CTL_MUT
## Islr2 2.259165e-39 -3.5357882 0.315 0.125 6.777495e-36 CTL_MUT
## Lxn 2.473282e-39 -2.8456888 0.224 0.089 7.419847e-36 CTL_MUT
## Amotl2 3.656900e-39 -1.6139526 0.193 0.019 1.097070e-35 CTL_MUT
## Myl12a 4.303855e-39 -0.4256264 0.208 0.049 1.291157e-35 CTL_MUT
## G0s2 4.981121e-39 -3.9828134 0.191 0.029 1.494336e-35 CTL_MUT
## Gstm5 7.465152e-39 -1.1183356 0.310 0.344 2.239546e-35 CTL_MUT
## Il1rap 1.653833e-38 3.3061934 0.293 0.082 4.961500e-35 CTL_MUT
## Tanc1 1.699059e-38 -2.2554598 0.205 0.049 5.097176e-35 CTL_MUT
## Sema6a 2.050555e-38 -4.7612355 0.229 0.068 6.151664e-35 CTL_MUT
## Scd2 4.488318e-38 -3.5665913 0.295 0.261 1.346495e-34 CTL_MUT
## Egr3 4.516927e-38 -2.3537763 0.275 0.167 1.355078e-34 CTL_MUT
## Shc4 4.738049e-38 -2.9705670 0.187 0.030 1.421415e-34 CTL_MUT
## Chaf1b 5.929263e-38 -5.0962516 0.170 0.057 1.778779e-34 CTL_MUT
## Hbb-bs 1.083471e-37 -2.9124135 0.217 0.224 3.250412e-34 CTL_MUT
## Ecm1 1.512479e-37 -2.0904723 0.233 0.032 4.537436e-34 CTL_MUT
## Mir99ahg 1.636970e-37 -1.5292606 0.273 0.103 4.910911e-34 CTL_MUT
## Igdcc3 2.500689e-37 -4.9815520 0.269 0.005 7.502068e-34 CTL_MUT
## A230006K03Rik 2.728282e-37 -3.6043660 0.276 0.103 8.184846e-34 CTL_MUT
## Plekhg2 5.759086e-37 -1.6506084 0.206 0.008 1.727726e-33 CTL_MUT
## Spsb2 6.665835e-37 2.5162121 0.171 0.021 1.999751e-33 CTL_MUT
## Ptn 7.916765e-37 -4.2053334 0.322 0.388 2.375030e-33 CTL_MUT
## Klf3 9.541693e-37 2.7312887 0.234 0.074 2.862508e-33 CTL_MUT
## Cygb 1.328837e-36 -4.1716862 0.232 0.087 3.986510e-33 CTL_MUT
## Wnt4 1.636272e-36 0.2577945 0.274 0.147 4.908817e-33 CTL_MUT
## Ccn3 1.949931e-36 0.4205889 0.249 0.124 5.849794e-33 CTL_MUT
## Lmnb1 2.097794e-36 1.2915642 0.135 0.050 6.293382e-33 CTL_MUT
## Rora 2.235567e-36 3.1032141 0.271 0.110 6.706700e-33 CTL_MUT
## Nptxr 2.954886e-36 2.1051999 0.352 0.385 8.864659e-33 CTL_MUT
## Arhgap29 3.434961e-36 -0.8954384 0.192 0.047 1.030488e-32 CTL_MUT
## Cyp26b1 4.024048e-36 -1.0023510 0.201 0.057 1.207214e-32 CTL_MUT
## Chn2 4.241792e-36 -0.4835661 0.238 0.074 1.272538e-32 CTL_MUT
## Trbc2 7.645094e-36 -2.6850322 0.255 0.163 2.293528e-32 CTL_MUT
## Adrb2 8.445568e-36 -3.0216716 0.184 0.007 2.533670e-32 CTL_MUT
## Clec14a 1.218743e-35 -2.3004513 0.166 0.007 3.656229e-32 CTL_MUT
## Endod1 1.247148e-35 -2.4363692 0.250 0.090 3.741443e-32 CTL_MUT
## H2-Eb1 1.872197e-35 -4.6251726 0.245 0.003 5.616592e-32 CTL_MUT
## Rnf144b 2.499176e-35 -3.5677315 0.187 0.023 7.497529e-32 CTL_MUT
## Phlda1 2.811708e-35 -2.8582874 0.268 0.102 8.435124e-32 CTL_MUT
## Ddr2 3.009255e-35 -3.5383670 0.218 0.007 9.027764e-32 CTL_MUT
## Phactr2 3.445669e-35 3.2173537 0.238 0.071 1.033701e-31 CTL_MUT
## Rab3c 3.544452e-35 -1.3868986 0.327 0.317 1.063335e-31 CTL_MUT
## Igfbp6 8.629791e-35 -1.7974263 0.295 0.187 2.588937e-31 CTL_MUT
## Vgf 1.139579e-34 -2.3666002 0.314 0.275 3.418738e-31 CTL_MUT
## Sfrp1 1.921926e-34 -1.2961337 0.179 0.031 5.765779e-31 CTL_MUT
## S100a10 2.064235e-34 -0.7888999 0.278 0.128 6.192704e-31 CTL_MUT
## Crabp1 2.606389e-34 -4.9103672 0.111 0.059 7.819167e-31 CTL_MUT
## Lap3 3.045264e-34 -2.2011863 0.219 0.068 9.135792e-31 CTL_MUT
## Ftx 3.828816e-34 -2.4773201 0.223 0.058 1.148645e-30 CTL_MUT
## Fth1 8.617302e-34 -0.6575679 0.333 0.403 2.585191e-30 CTL_MUT
## Sema3b 1.023589e-33 -4.5288612 0.229 0.157 3.070768e-30 CTL_MUT
## Btg2 2.202010e-33 -2.3914570 0.247 0.136 6.606031e-30 CTL_MUT
## Etv1 2.455002e-33 -1.9405045 0.256 0.163 7.365005e-30 CTL_MUT
## Scg2 2.749817e-33 -2.0660088 0.308 0.289 8.249452e-30 CTL_MUT
## Nfkbie 4.351988e-33 -3.9011089 0.164 0.017 1.305597e-29 CTL_MUT
## Ago3 4.899424e-33 4.0365386 0.306 0.117 1.469827e-29 CTL_MUT
## Fst 5.383730e-33 -3.2198691 0.238 0.016 1.615119e-29 CTL_MUT
## Mylk 1.294992e-32 -1.6318755 0.189 0.052 3.884976e-29 CTL_MUT
## Sapcd2 1.362443e-32 -4.3889766 0.115 0.052 4.087329e-29 CTL_MUT
## Lhfpl2 1.373625e-32 -4.1459777 0.231 0.023 4.120876e-29 CTL_MUT
## Golim4 3.897678e-32 0.2941635 0.196 0.047 1.169303e-28 CTL_MUT
## Pnpla2 5.701426e-32 -0.6033423 0.207 0.040 1.710428e-28 CTL_MUT
## Syndig1l 6.614311e-32 -5.8396674 0.221 0.040 1.984293e-28 CTL_MUT
## Alcam 2.970175e-31 2.6309113 0.337 0.252 8.910525e-28 CTL_MUT
## Edil3 3.318764e-31 0.6178506 0.266 0.137 9.956292e-28 CTL_MUT
## Xdh 3.475724e-31 -3.0265284 0.201 0.011 1.042717e-27 CTL_MUT
## Fnbp1 3.668253e-31 -3.6635811 0.264 0.097 1.100476e-27 CTL_MUT
## Limd1 4.765297e-31 -2.2570175 0.206 0.028 1.429589e-27 CTL_MUT
## Bc1 5.030483e-31 4.0014942 0.377 0.449 1.509145e-27 CTL_MUT
## Egr2 5.254679e-31 -3.4782837 0.249 0.024 1.576404e-27 CTL_MUT
## Parvb 5.808799e-31 -2.8318152 0.153 0.026 1.742640e-27 CTL_MUT
## Gm47644 9.075590e-31 -2.6773510 0.313 0.012 2.722677e-27 CTL_MUT
## Igfbp3 1.374179e-30 -5.7167855 0.241 0.017 4.122537e-27 CTL_MUT
## Slc2a1 3.463274e-30 -3.4665855 0.184 0.089 1.038982e-26 CTL_MUT
## Sox8 4.700238e-30 -2.5954380 0.221 0.074 1.410071e-26 CTL_MUT
## Selenow 4.854635e-30 0.5163216 0.396 0.470 1.456390e-26 CTL_MUT
## Gbp7 4.976482e-30 -0.3384822 0.196 0.015 1.492945e-26 CTL_MUT
## Id2 5.028035e-30 1.2637237 0.266 0.206 1.508410e-26 CTL_MUT
## Ifi203 7.424470e-30 -2.8206538 0.240 0.008 2.227341e-26 CTL_MUT
## Atp11c 1.091011e-29 -1.7188956 0.252 0.015 3.273033e-26 CTL_MUT
## Anxa5 1.101688e-29 -0.4390231 0.286 0.113 3.305063e-26 CTL_MUT
## Sall3 1.739174e-29 -2.6778699 0.149 0.032 5.217522e-26 CTL_MUT
## Etv4 2.010011e-29 -2.7180619 0.237 0.014 6.030034e-26 CTL_MUT
## Nrtn 2.283938e-29 -3.0882996 0.242 0.022 6.851815e-26 CTL_MUT
## Dnajb2 3.081490e-29 4.0977066 0.292 0.138 9.244470e-26 CTL_MUT
## Gpr4 3.412073e-29 -5.2962681 0.179 0.010 1.023622e-25 CTL_MUT
## Mtss2 5.909924e-29 -0.9745997 0.259 0.102 1.772977e-25 CTL_MUT
## Rgs4 7.777927e-29 1.6432665 0.331 0.390 2.333378e-25 CTL_MUT
## Dmd 1.004807e-28 1.7988595 0.327 0.147 3.014421e-25 CTL_MUT
## Gapdh 1.025609e-28 -0.2632615 0.405 0.468 3.076826e-25 CTL_MUT
## Ppfibp1 1.370023e-28 -3.5789022 0.227 0.076 4.110068e-25 CTL_MUT
## Fzd4 1.387682e-28 -1.8272307 0.174 0.022 4.163045e-25 CTL_MUT
## Mcm7 1.697260e-28 -3.6984117 0.221 0.037 5.091779e-25 CTL_MUT
## Ddah1 1.935892e-28 0.3745300 0.281 0.164 5.807677e-25 CTL_MUT
## Mtss1 2.439071e-28 -1.7232625 0.257 0.078 7.317213e-25 CTL_MUT
## Filip1l 3.153258e-28 -3.0657285 0.195 0.035 9.459775e-25 CTL_MUT
## Ablim1 4.834554e-28 -1.9325158 0.384 0.186 1.450366e-24 CTL_MUT
## Nme7 5.110070e-28 3.6996309 0.316 0.229 1.533021e-24 CTL_MUT
## Camk2n2 6.207985e-28 1.1025272 0.311 0.253 1.862395e-24 CTL_MUT
## Zic3 6.930256e-28 -3.8214753 0.208 0.005 2.079077e-24 CTL_MUT
## Ier3 7.382709e-28 -3.3077745 0.241 0.073 2.214813e-24 CTL_MUT
## Sept4 8.024960e-28 -1.6048103 0.270 0.139 2.407488e-24 CTL_MUT
## Gm26879 1.217191e-27 -5.0890018 0.236 0.022 3.651574e-24 CTL_MUT
## Prkcg 1.885368e-27 0.6649225 0.367 0.274 5.656103e-24 CTL_MUT
## Btg1 2.037331e-27 -0.6978954 0.261 0.119 6.111994e-24 CTL_MUT
## Rilpl1 3.035220e-27 0.9872911 0.278 0.166 9.105660e-24 CTL_MUT
## Pacs2 3.703261e-27 -0.7178983 0.212 0.044 1.110978e-23 CTL_MUT
## Hmgn2 4.335965e-27 -1.5485202 0.252 0.121 1.300789e-23 CTL_MUT
## Nrp1 6.351688e-27 3.7802173 0.286 0.085 1.905506e-23 CTL_MUT
## Tyms 6.619329e-27 -4.8884240 0.229 0.011 1.985799e-23 CTL_MUT
## 4632427E13Rik 7.090293e-27 -1.9472427 0.340 0.115 2.127088e-23 CTL_MUT
## Fosb 1.533550e-26 -2.5028338 0.232 0.148 4.600649e-23 CTL_MUT
## Thsd7a 3.555226e-26 -1.7491376 0.203 0.086 1.066568e-22 CTL_MUT
## Nfia 4.144139e-26 0.3621198 0.286 0.169 1.243242e-22 CTL_MUT
## Acsl3 4.764676e-26 -2.6244876 0.276 0.227 1.429403e-22 CTL_MUT
## Sfrp4 4.813702e-26 -5.5996050 0.301 0.005 1.444111e-22 CTL_MUT
## Cntnap5a 5.213843e-26 -2.9020954 0.286 0.089 1.564153e-22 CTL_MUT
## Hcn1 7.049301e-26 3.0392953 0.315 0.171 2.114790e-22 CTL_MUT
## Slc16a13 7.392029e-26 -5.3981708 0.264 0.009 2.217609e-22 CTL_MUT
## Marcksl1 8.352181e-26 3.1721792 0.318 0.294 2.505654e-22 CTL_MUT
## Nes 8.652007e-26 -2.9086480 0.182 0.021 2.595602e-22 CTL_MUT
## Sgk1 9.596888e-26 -3.3829680 0.268 0.109 2.879067e-22 CTL_MUT
## Cdkn1c 9.723183e-26 -3.2130007 0.251 0.032 2.916955e-22 CTL_MUT
## Ntn1 1.620244e-25 -3.2173698 0.166 0.043 4.860732e-22 CTL_MUT
## A330023F24Rik 1.625997e-25 1.1767308 0.287 0.069 4.877991e-22 CTL_MUT
## Stk38 1.768505e-25 -5.6267271 0.328 0.115 5.305515e-22 CTL_MUT
## Pdcd4 1.868117e-25 -3.9758112 0.310 0.265 5.604352e-22 CTL_MUT
## Rprm 1.942110e-25 -3.5274272 0.260 0.140 5.826331e-22 CTL_MUT
## 5330434G04Rik 2.572485e-25 -1.6870783 0.295 0.126 7.717455e-22 CTL_MUT
## Cntnap2 3.340032e-25 3.6041744 0.281 0.154 1.002010e-21 CTL_MUT
## Cmtm6 5.382293e-25 -4.5313978 0.211 0.015 1.614688e-21 CTL_MUT
## Rgs2 5.735735e-25 -4.5612773 0.274 0.171 1.720720e-21 CTL_MUT
## Hbp1 6.436795e-25 1.5938033 0.235 0.067 1.931039e-21 CTL_MUT
## Nrip3 6.595746e-25 -4.1795287 0.284 0.157 1.978724e-21 CTL_MUT
## Resp18 7.067206e-25 -1.3502240 0.298 0.194 2.120162e-21 CTL_MUT
## Cpne5 9.745714e-25 -0.7347007 0.313 0.229 2.923714e-21 CTL_MUT
## Tle4 1.138047e-24 -4.8194431 0.281 0.123 3.414142e-21 CTL_MUT
## Rai14 1.179076e-24 -1.4806100 0.265 0.032 3.537227e-21 CTL_MUT
## Camk2d 1.349036e-24 0.9067793 0.288 0.191 4.047107e-21 CTL_MUT
## Pbx3 1.603014e-24 0.4908517 0.175 0.056 4.809043e-21 CTL_MUT
## Chchd10 2.111164e-24 1.5171314 0.378 0.435 6.333492e-21 CTL_MUT
## Birc3 2.221366e-24 -3.6005917 0.141 0.020 6.664098e-21 CTL_MUT
## Satb1 2.497700e-24 -1.6718985 0.302 0.097 7.493100e-21 CTL_MUT
## Bpgm 3.120259e-24 -2.3906554 0.270 0.135 9.360776e-21 CTL_MUT
## Grk3 4.689961e-24 0.4064488 0.291 0.098 1.406988e-20 CTL_MUT
## Myo1b 6.096229e-24 4.5452734 0.255 0.064 1.828869e-20 CTL_MUT
## Ccdc141 7.461166e-24 1.2846686 0.158 0.047 2.238350e-20 CTL_MUT
## Hist1h2ae 9.440860e-24 -3.4664372 0.229 0.036 2.832258e-20 CTL_MUT
## Tubb3 1.039095e-23 1.6630243 0.349 0.436 3.117286e-20 CTL_MUT
## Scn1b 1.088579e-23 0.7314334 0.371 0.424 3.265738e-20 CTL_MUT
## Grb14 1.202884e-23 -4.9927658 0.252 0.106 3.608653e-20 CTL_MUT
## Nt5dc2 1.345953e-23 -2.0905370 0.187 0.016 4.037858e-20 CTL_MUT
## Cux1 2.631725e-23 0.9824009 0.254 0.137 7.895175e-20 CTL_MUT
## Gucy1a1 3.186607e-23 -6.5424776 0.273 0.177 9.559821e-20 CTL_MUT
## Nrsn2 4.432418e-23 -0.2740515 0.250 0.124 1.329725e-19 CTL_MUT
## Ldhb 5.112024e-23 0.5093906 0.362 0.426 1.533607e-19 CTL_MUT
## Sik1 9.040287e-23 -2.3421979 0.262 0.056 2.712086e-19 CTL_MUT
## Clk1 1.486123e-22 1.6393706 0.337 0.189 4.458370e-19 CTL_MUT
## Nrn1 1.520722e-22 -0.4726952 0.309 0.323 4.562166e-19 CTL_MUT
## Atp1b1 1.780672e-22 0.9492816 0.390 0.443 5.342016e-19 CTL_MUT
## Jmjd1c 2.000216e-22 -0.4662854 0.332 0.176 6.000649e-19 CTL_MUT
## Garnl3 3.605114e-22 -1.0936577 0.293 0.104 1.081534e-18 CTL_MUT
## Pcp4 3.642217e-22 -3.5364231 0.341 0.381 1.092665e-18 CTL_MUT
## Rgs16 4.080264e-22 -2.5416391 0.251 0.014 1.224079e-18 CTL_MUT
## Kitl 4.378530e-22 -1.7210782 0.292 0.133 1.313559e-18 CTL_MUT
## Tiam1 9.493249e-22 0.6066950 0.275 0.115 2.847975e-18 CTL_MUT
## Ramp1 1.274601e-21 0.6439070 0.335 0.306 3.823803e-18 CTL_MUT
## Arhgef10 1.325615e-21 -3.4169648 0.218 0.022 3.976846e-18 CTL_MUT
## Frmd4a 1.926719e-21 -4.1591906 0.307 0.155 5.780156e-18 CTL_MUT
## Mgll 1.977451e-21 -2.9002733 0.335 0.282 5.932353e-18 CTL_MUT
## Hpca 2.197438e-21 -0.2970961 0.370 0.401 6.592314e-18 CTL_MUT
## Iqgap1 2.223647e-21 -2.4316110 0.309 0.086 6.670942e-18 CTL_MUT
## Igfbp4 2.277194e-21 -4.0607329 0.215 0.102 6.831582e-18 CTL_MUT
## Dtna 2.415664e-21 0.8665444 0.317 0.195 7.246993e-18 CTL_MUT
## Maml2 3.764153e-21 -2.3396274 0.183 0.021 1.129246e-17 CTL_MUT
## Tet2 4.719749e-21 -5.3863858 0.297 0.089 1.415925e-17 CTL_MUT
## Insr 5.322176e-21 3.1190612 0.278 0.064 1.596653e-17 CTL_MUT
## Nr4a1 6.200873e-21 -1.8024987 0.269 0.097 1.860262e-17 CTL_MUT
## Syt4 7.234150e-21 0.8634181 0.343 0.346 2.170245e-17 CTL_MUT
## Egr4 1.276904e-20 -5.0245148 0.257 0.146 3.830711e-17 CTL_MUT
## Csmd3 1.554821e-20 0.6817834 0.319 0.123 4.664462e-17 CTL_MUT
## Lmo7 1.699979e-20 -2.8947064 0.324 0.142 5.099936e-17 CTL_MUT
## Elavl2 2.057823e-20 2.7095650 0.338 0.184 6.173469e-17 CTL_MUT
## Jpt1 4.970604e-20 -4.7011832 0.351 0.359 1.491181e-16 CTL_MUT
## Gm26917 5.076667e-20 1.3034058 0.308 0.168 1.523000e-16 CTL_MUT
## Ptprg 5.793143e-20 -2.1727372 0.293 0.113 1.737943e-16 CTL_MUT
## Snap25 6.555575e-20 -0.4355939 0.395 0.455 1.966672e-16 CTL_MUT
## Cpsf6 6.597601e-20 1.2220789 0.346 0.158 1.979280e-16 CTL_MUT
## Camk2n1 8.351067e-20 1.4907374 0.353 0.399 2.505320e-16 CTL_MUT
## Swap70 1.403303e-19 -0.8653457 0.169 0.028 4.209910e-16 CTL_MUT
## Chst7 1.712301e-19 -4.1273525 0.150 0.049 5.136903e-16 CTL_MUT
## Tshz2 1.780749e-19 -0.2570813 0.167 0.081 5.342246e-16 CTL_MUT
## Snca 2.501683e-19 -1.0059206 0.361 0.375 7.505048e-16 CTL_MUT
## Trank1 3.401765e-19 1.1726509 0.290 0.107 1.020529e-15 CTL_MUT
## Fbxo2 3.415365e-19 -4.5204557 0.259 0.191 1.024610e-15 CTL_MUT
## Sptbn1 3.650960e-19 -1.6724181 0.435 0.423 1.095288e-15 CTL_MUT
## Atp2a2 5.102969e-19 2.1115635 0.473 0.440 1.530891e-15 CTL_MUT
## Hs3st4 6.513953e-19 -1.0902317 0.246 0.086 1.954186e-15 CTL_MUT
## Klf6 7.178469e-19 -2.5334383 0.312 0.175 2.153541e-15 CTL_MUT
## Foxp2 8.008329e-19 -4.0571573 0.217 0.025 2.402499e-15 CTL_MUT
## Myl4 1.116973e-18 -1.5852410 0.182 0.154 3.350918e-15 CTL_MUT
## Tnfsf12 1.139609e-18 -2.5878347 0.224 0.012 3.418826e-15 CTL_MUT
## Hs3st2 1.367615e-18 0.6916212 0.297 0.128 4.102846e-15 CTL_MUT
## Msmo1 1.570970e-18 -2.1166937 0.301 0.201 4.712910e-15 CTL_MUT
## Tmem140 2.247859e-18 -2.9460759 0.199 0.006 6.743577e-15 CTL_MUT
## Csrp2 2.256191e-18 -1.3894290 0.179 0.041 6.768572e-15 CTL_MUT
## Rxrg 3.490789e-18 -4.8439108 0.210 0.017 1.047237e-14 CTL_MUT
## Tesc 4.324843e-18 1.7281947 0.320 0.269 1.297453e-14 CTL_MUT
## Ramp3 5.301142e-18 -1.3922479 0.252 0.085 1.590343e-14 CTL_MUT
## Eml5 6.115500e-18 -4.7057302 0.334 0.122 1.834650e-14 CTL_MUT
## Vwa1 6.722013e-18 -2.3096672 0.191 0.051 2.016604e-14 CTL_MUT
## A2ml1 8.879671e-18 -1.3584526 0.241 0.092 2.663901e-14 CTL_MUT
## Bdnf 1.015525e-17 1.0355319 0.256 0.148 3.046575e-14 CTL_MUT
## Sdk2 1.078894e-17 -0.6196145 0.337 0.093 3.236681e-14 CTL_MUT
## Cd2ap 1.633003e-17 -4.3122421 0.313 0.110 4.899009e-14 CTL_MUT
## Tnr 2.014965e-17 -0.9363717 0.307 0.174 6.044895e-14 CTL_MUT
## Atp6v0c 2.094950e-17 0.8570226 0.452 0.485 6.284851e-14 CTL_MUT
## Tmeff2 4.024326e-17 -4.7373515 0.277 0.122 1.207298e-13 CTL_MUT
## Prorsd1 5.169727e-17 -5.0057585 0.275 0.010 1.550918e-13 CTL_MUT
## Lrp1 5.530562e-17 2.5694392 0.332 0.164 1.659169e-13 CTL_MUT
## Dynll1 5.655125e-17 -0.2680567 0.410 0.461 1.696537e-13 CTL_MUT
## Dkk3 7.526938e-17 4.3824521 0.339 0.235 2.258081e-13 CTL_MUT
## Atp1b3 1.016578e-16 3.4553448 0.318 0.129 3.049734e-13 CTL_MUT
## Pid1 1.272133e-16 1.9721226 0.295 0.147 3.816399e-13 CTL_MUT
## Mcm6 1.389822e-16 -3.8093645 0.211 0.010 4.169465e-13 CTL_MUT
## Cplx1 1.721464e-16 -0.3433521 0.312 0.255 5.164393e-13 CTL_MUT
## Scg3 1.845712e-16 -2.6763778 0.295 0.290 5.537135e-13 CTL_MUT
## Nfkbia 2.130551e-16 -1.4983668 0.221 0.111 6.391654e-13 CTL_MUT
## Aurka 2.344583e-16 -4.0196728 0.215 0.011 7.033749e-13 CTL_MUT
## Cpne4 2.355212e-16 -3.5321719 0.251 0.151 7.065636e-13 CTL_MUT
## Srcin1 3.101241e-16 4.4566803 0.406 0.221 9.303722e-13 CTL_MUT
## Gpm6b 3.490062e-16 -0.5485682 0.343 0.384 1.047019e-12 CTL_MUT
## Parp12 3.795857e-16 -2.1180681 0.235 0.011 1.138757e-12 CTL_MUT
## Net1 3.852211e-16 -3.0454336 0.204 0.050 1.155663e-12 CTL_MUT
## Tox3 3.961520e-16 -2.7580004 0.213 0.077 1.188456e-12 CTL_MUT
## 4930488L21Rik 4.583875e-16 -2.1657522 0.200 0.010 1.375163e-12 CTL_MUT
## Limch1 5.591157e-16 2.3890747 0.297 0.152 1.677347e-12 CTL_MUT
## Rps26 7.959290e-16 3.6787808 0.364 0.391 2.387787e-12 CTL_MUT
## Kif1b 8.634677e-16 4.1293393 0.471 0.443 2.590403e-12 CTL_MUT
## Mdh1 9.494978e-16 -0.5098704 0.394 0.411 2.848493e-12 CTL_MUT
## Dst 1.082603e-15 4.7919389 0.442 0.346 3.247810e-12 CTL_MUT
## Pcsk1n 1.248002e-15 1.3749307 0.393 0.408 3.744005e-12 CTL_MUT
## Kcnk2 1.348441e-15 -4.2604330 0.262 0.155 4.045323e-12 CTL_MUT
## Shtn1 1.356770e-15 -1.5219943 0.308 0.114 4.070311e-12 CTL_MUT
## Rel 1.433216e-15 -1.6657936 0.211 0.054 4.299648e-12 CTL_MUT
## Tubb2a 1.869485e-15 -0.4310265 0.379 0.421 5.608454e-12 CTL_MUT
## Sfrp2 2.229791e-15 -4.0504793 0.204 0.012 6.689372e-12 CTL_MUT
## Fabp5 2.371451e-15 -1.4683173 0.351 0.409 7.114353e-12 CTL_MUT
## Gm47664 3.418850e-15 -2.5812024 0.279 0.081 1.025655e-11 CTL_MUT
## Lrfn5 3.440899e-15 2.9523758 0.358 0.185 1.032270e-11 CTL_MUT
## Ntm 4.175003e-15 1.0885723 0.382 0.444 1.252501e-11 CTL_MUT
## Prxl2a 4.469014e-15 -2.5840547 0.296 0.176 1.340704e-11 CTL_MUT
## P2ry14 5.452531e-15 -2.8046297 0.231 0.039 1.635759e-11 CTL_MUT
## C78859 5.497836e-15 -2.9760561 0.295 0.115 1.649351e-11 CTL_MUT
## Gadd45g 8.007608e-15 -2.0851196 0.290 0.200 2.402282e-11 CTL_MUT
## Cdk6 9.195562e-15 -0.7068015 0.215 0.016 2.758669e-11 CTL_MUT
## C1ql2 1.082906e-14 -4.3213767 0.159 0.078 3.248717e-11 CTL_MUT
## Necab1 1.182238e-14 -1.7040413 0.265 0.143 3.546714e-11 CTL_MUT
## Hexa 1.553834e-14 -5.2052854 0.282 0.128 4.661501e-11 CTL_MUT
## Amt 1.661628e-14 -3.4064594 0.189 0.027 4.984883e-11 CTL_MUT
## Calm1 1.889816e-14 -0.3606906 0.445 0.485 5.669449e-11 CTL_MUT
## Cspp1 2.181475e-14 2.6663090 0.348 0.148 6.544425e-11 CTL_MUT
## Hmgcs1 2.230489e-14 -2.4745524 0.343 0.319 6.691466e-11 CTL_MUT
## Picalm 2.431082e-14 -1.3145885 0.289 0.161 7.293247e-11 CTL_MUT
## Ank3 3.235035e-14 -2.9757413 0.443 0.383 9.705104e-11 CTL_MUT
## Ctsd 3.389954e-14 -0.6939638 0.299 0.275 1.016986e-10 CTL_MUT
## Myh9 3.428681e-14 -2.0990732 0.281 0.112 1.028604e-10 CTL_MUT
## Ifnar1 4.583669e-14 -3.8131448 0.290 0.085 1.375101e-10 CTL_MUT
## Enc1 6.207268e-14 4.3453146 0.374 0.383 1.862180e-10 CTL_MUT
## Rnaset2a 7.373813e-14 -3.6635173 0.199 0.042 2.212144e-10 CTL_MUT
## Map3k1 8.662266e-14 -3.8217481 0.168 0.033 2.598680e-10 CTL_MUT
## Cspg5 1.059803e-13 -2.5706057 0.286 0.323 3.179408e-10 CTL_MUT
## C1qtnf4 1.343294e-13 2.0706906 0.384 0.425 4.029883e-10 CTL_MUT
## Nasp 1.535461e-13 -2.2342883 0.283 0.104 4.606383e-10 CTL_MUT
## 4930402H24Rik 1.717150e-13 -0.6742806 0.327 0.119 5.151451e-10 CTL_MUT
## Cdh13 1.770958e-13 -2.2793244 0.313 0.133 5.312874e-10 CTL_MUT
## Dach1 2.070855e-13 -2.9914749 0.224 0.015 6.212566e-10 CTL_MUT
## Fxyd6 2.697461e-13 -2.8168841 0.341 0.277 8.092383e-10 CTL_MUT
## Cttnbp2nl 3.172206e-13 -2.0677760 0.245 0.066 9.516619e-10 CTL_MUT
## Grasp 3.200768e-13 0.3666146 0.302 0.222 9.602304e-10 CTL_MUT
## Prdx1 3.463739e-13 -1.7120780 0.337 0.315 1.039122e-09 CTL_MUT
## Spry1 3.516693e-13 -2.1677598 0.219 0.018 1.055008e-09 CTL_MUT
## Bst2 3.593672e-13 -1.7074454 0.172 0.017 1.078102e-09 CTL_MUT
## Gap43 3.789088e-13 0.4059155 0.377 0.430 1.136726e-09 CTL_MUT
## Gm43445 3.980500e-13 1.8314603 0.215 0.049 1.194150e-09 CTL_MUT
## Col4a2 4.425407e-13 -1.3971535 0.225 0.068 1.327622e-09 CTL_MUT
## Col5a3 4.904914e-13 -4.5829443 0.224 0.021 1.471474e-09 CTL_MUT
## Cacna1e 5.248393e-13 0.9466453 0.412 0.223 1.574518e-09 CTL_MUT
## Atpif1 6.018195e-13 -0.2750122 0.407 0.413 1.805459e-09 CTL_MUT
## Pcdh9 6.537267e-13 1.7263549 0.405 0.257 1.961180e-09 CTL_MUT
## Hpcal1 6.876821e-13 -2.2630323 0.278 0.095 2.063046e-09 CTL_MUT
## Angptl2 7.757864e-13 -2.0322432 0.201 0.050 2.327359e-09 CTL_MUT
## Trhde 8.564167e-13 -2.5744315 0.291 0.097 2.569250e-09 CTL_MUT
## Stmn3 9.432202e-13 1.2660802 0.440 0.465 2.829661e-09 CTL_MUT
## Gm13187 9.949217e-13 -3.6635968 0.262 0.004 2.984765e-09 CTL_MUT
## Cwc22 1.194374e-12 2.2737766 0.349 0.217 3.583122e-09 CTL_MUT
## Nrgn 1.210765e-12 -2.7863908 0.374 0.397 3.632296e-09 CTL_MUT
## Slc3a2 1.233617e-12 4.0615012 0.350 0.238 3.700850e-09 CTL_MUT
## Serpini1 1.334518e-12 4.4296985 0.326 0.214 4.003555e-09 CTL_MUT
## Ptpre 1.423014e-12 3.4995901 0.318 0.121 4.269042e-09 CTL_MUT
## 1110008P14Rik 1.972786e-12 0.7230301 0.352 0.385 5.918359e-09 CTL_MUT
## Plcb4 2.123214e-12 -2.7656043 0.297 0.170 6.369642e-09 CTL_MUT
## Stmn2 2.759927e-12 0.9886599 0.430 0.466 8.279780e-09 CTL_MUT
## Stc1 3.104221e-12 -1.5468339 0.260 0.013 9.312663e-09 CTL_MUT
## Nell2 4.305594e-12 -0.9957530 0.383 0.360 1.291678e-08 CTL_MUT
## Crym 4.425413e-12 -1.7073273 0.342 0.268 1.327624e-08 CTL_MUT
## Gsta4 4.884442e-12 -3.4481835 0.285 0.126 1.465332e-08 CTL_MUT
## Tcf12 5.271592e-12 1.1217977 0.301 0.103 1.581478e-08 CTL_MUT
## Rock1 6.533122e-12 2.2283267 0.343 0.134 1.959937e-08 CTL_MUT
## Mif 7.049858e-12 -0.8521588 0.398 0.403 2.114957e-08 CTL_MUT
## Rhoj 7.426325e-12 -3.0924317 0.187 0.013 2.227898e-08 CTL_MUT
## Nfat5 9.568070e-12 3.6870743 0.361 0.149 2.870421e-08 CTL_MUT
## Spaca6 1.021061e-11 -0.7739542 0.318 0.107 3.063184e-08 CTL_MUT
## Prnp 1.118211e-11 0.5987662 0.387 0.436 3.354634e-08 CTL_MUT
## Lingo1 1.297750e-11 1.4061724 0.380 0.377 3.893249e-08 CTL_MUT
## Fos 1.368975e-11 -3.5809357 0.270 0.296 4.106924e-08 CTL_MUT
## Fermt2 1.625635e-11 0.6007298 0.289 0.180 4.876906e-08 CTL_MUT
## Gng12 1.716337e-11 -2.3371775 0.286 0.114 5.149011e-08 CTL_MUT
## Gm10115 2.014123e-11 -1.0200003 0.310 0.130 6.042368e-08 CTL_MUT
## Marcks 2.233410e-11 -3.7128888 0.344 0.359 6.700231e-08 CTL_MUT
## Tuba1a 2.319529e-11 -3.3734414 0.366 0.421 6.958588e-08 CTL_MUT
## Tjp1 2.344274e-11 -0.4475601 0.292 0.137 7.032822e-08 CTL_MUT
## Uchl1 2.383922e-11 0.6486206 0.418 0.444 7.151766e-08 CTL_MUT
## Cadm1 3.155779e-11 -0.8238816 0.325 0.227 9.467337e-08 CTL_MUT
## Cav1 3.243897e-11 -2.8812787 0.203 0.014 9.731691e-08 CTL_MUT
## Aff1 3.540126e-11 -2.6316873 0.190 0.015 1.062038e-07 CTL_MUT
## Cpe 4.142764e-11 -0.5348691 0.361 0.401 1.242829e-07 CTL_MUT
## Man2b1 4.365032e-11 -3.4791925 0.296 0.106 1.309510e-07 CTL_MUT
## Ubn2 4.484424e-11 1.0365594 0.350 0.165 1.345327e-07 CTL_MUT
## Tmpo 4.500999e-11 -1.8066455 0.260 0.089 1.350300e-07 CTL_MUT
## Slc6a6 4.782906e-11 -2.3091958 0.329 0.137 1.434872e-07 CTL_MUT
## Rps19 5.719045e-11 3.6041813 0.355 0.430 1.715713e-07 CTL_MUT
## Aplp1 6.749994e-11 1.3235305 0.384 0.402 2.024998e-07 CTL_MUT
## Bhlhe22 9.939264e-11 -0.3572314 0.222 0.093 2.981779e-07 CTL_MUT
## Ank2 1.143761e-10 1.6802513 0.450 0.438 3.431284e-07 CTL_MUT
## Dnajb1 1.201243e-10 -0.9734027 0.298 0.133 3.603728e-07 CTL_MUT
## Hmgcr 1.399923e-10 -0.8040282 0.365 0.330 4.199770e-07 CTL_MUT
## Cabp1 1.408495e-10 2.5057518 0.327 0.289 4.225485e-07 CTL_MUT
## Pam 1.417745e-10 -5.5806451 0.329 0.261 4.253235e-07 CTL_MUT
## Sel1l3 1.574812e-10 -3.6784422 0.326 0.110 4.724435e-07 CTL_MUT
## Fam13c 1.612866e-10 -0.2861118 0.324 0.148 4.838597e-07 CTL_MUT
## Ppp1r1b 1.785234e-10 -4.9985162 0.247 0.084 5.355701e-07 CTL_MUT
## Syt6 1.880572e-10 -1.0918798 0.233 0.057 5.641716e-07 CTL_MUT
## Cd81 1.934246e-10 -3.4759579 0.322 0.383 5.802738e-07 CTL_MUT
## Grin2b 2.816951e-10 -2.4144604 0.464 0.424 8.450854e-07 CTL_MUT
## Ndn 2.922152e-10 4.9280663 0.344 0.267 8.766456e-07 CTL_MUT
## Rgs10 3.082805e-10 -2.5075048 0.220 0.090 9.248415e-07 CTL_MUT
## Mxd4 3.116821e-10 3.3532653 0.351 0.156 9.350463e-07 CTL_MUT
## Ctsl 3.601705e-10 -3.6291661 0.324 0.239 1.080512e-06 CTL_MUT
## Cacna1a 5.194849e-10 0.5205823 0.399 0.195 1.558455e-06 CTL_MUT
## Gabra1 5.685495e-10 -2.7782365 0.370 0.296 1.705648e-06 CTL_MUT
## Anp32b 6.314406e-10 -2.0697968 0.309 0.183 1.894322e-06 CTL_MUT
## Kctd16 6.433398e-10 3.0800993 0.351 0.252 1.930019e-06 CTL_MUT
## Hap1 6.639176e-10 -6.1369208 0.264 0.110 1.991753e-06 CTL_MUT
## Ifi27 7.103167e-10 3.7664195 0.270 0.111 2.130950e-06 CTL_MUT
## Pde1a 7.818836e-10 -1.1046614 0.380 0.331 2.345651e-06 CTL_MUT
## Rplp0 8.121539e-10 -0.8800332 0.319 0.346 2.436462e-06 CTL_MUT
## Hnrnpa1 8.474133e-10 -4.7716405 0.292 0.240 2.542240e-06 CTL_MUT
## Bcl11a 1.963874e-09 3.6612609 0.353 0.211 5.891623e-06 CTL_MUT
## Grin2a 2.252153e-09 4.7135819 0.437 0.341 6.756460e-06 CTL_MUT
## Kcnc1 2.535310e-09 -3.0422894 0.352 0.167 7.605929e-06 CTL_MUT
## Pebp1 2.722796e-09 -0.3702203 0.420 0.441 8.168387e-06 CTL_MUT
## Gprc5c 2.894834e-09 -1.4695391 0.170 0.013 8.684503e-06 CTL_MUT
## Junb 4.148856e-09 -2.6078167 0.305 0.245 1.244657e-05 CTL_MUT
## A830036E02Rik 4.864141e-09 0.6890457 0.275 0.110 1.459242e-05 CTL_MUT
## Plcxd2 5.453516e-09 -3.8117998 0.214 0.108 1.636055e-05 CTL_MUT
## Fat3 6.020589e-09 1.4192627 0.292 0.167 1.806177e-05 CTL_MUT
## Meis2 6.106401e-09 -1.1633866 0.342 0.315 1.831920e-05 CTL_MUT
## Fry 7.208732e-09 4.6517072 0.361 0.226 2.162620e-05 CTL_MUT
## Ubc 7.299462e-09 2.5463646 0.370 0.427 2.189839e-05 CTL_MUT
## Suclg2 7.627242e-09 -2.2180095 0.203 0.018 2.288173e-05 CTL_MUT
## Gadd45b 7.821967e-09 -5.0110356 0.267 0.137 2.346590e-05 CTL_MUT
## Gnai2 9.243455e-09 0.2559263 0.318 0.246 2.773036e-05 CTL_MUT
## Stmn1 9.245172e-09 1.5643909 0.429 0.454 2.773552e-05 CTL_MUT
## Slc1a2 1.164864e-08 -0.3693525 0.294 0.292 3.494591e-05 CTL_MUT
## Leng8 1.206426e-08 -2.9509922 0.335 0.136 3.619277e-05 CTL_MUT
## Unc80 1.315696e-08 -1.2446216 0.389 0.220 3.947088e-05 CTL_MUT
## Pdzd2 1.453790e-08 -3.1135626 0.280 0.094 4.361370e-05 CTL_MUT
## Foxp1 1.472729e-08 1.5260296 0.394 0.264 4.418186e-05 CTL_MUT
## Secisbp2l 1.765213e-08 -2.5860679 0.321 0.198 5.295638e-05 CTL_MUT
## Car4 1.784916e-08 -1.5806143 0.245 0.087 5.354748e-05 CTL_MUT
## Nav2 2.032011e-08 -2.4953645 0.389 0.208 6.096034e-05 CTL_MUT
## Ddx17 2.277463e-08 4.4433672 0.360 0.261 6.832388e-05 CTL_MUT
## Esyt2 2.540303e-08 2.2664587 0.302 0.102 7.620909e-05 CTL_MUT
## Taldo1 2.888493e-08 -3.2227163 0.325 0.266 8.665478e-05 CTL_MUT
## Fut9 3.472124e-08 -3.1002942 0.405 0.275 1.041637e-04 CTL_MUT
## Def6 3.545959e-08 -4.7820512 0.262 0.010 1.063788e-04 CTL_MUT
## Pde1b 3.959005e-08 0.8428296 0.269 0.108 1.187701e-04 CTL_MUT
## Rnf13 4.146742e-08 -3.8481262 0.312 0.114 1.244023e-04 CTL_MUT
## Krt12 4.439101e-08 -0.8210801 0.246 0.115 1.331730e-04 CTL_MUT
## Rdx 5.403165e-08 -4.0466931 0.325 0.207 1.620949e-04 CTL_MUT
## Npas4 5.772060e-08 -5.0839074 0.322 0.193 1.731618e-04 CTL_MUT
## Chga 6.127967e-08 2.4970075 0.343 0.320 1.838390e-04 CTL_MUT
## Map4k4 6.129968e-08 -2.3195346 0.320 0.190 1.838990e-04 CTL_MUT
## Grp 6.960151e-08 -2.6195988 0.258 0.073 2.088045e-04 CTL_MUT
## Gng3 7.303495e-08 -0.5555279 0.416 0.456 2.191048e-04 CTL_MUT
## Snrnp70 8.163263e-08 2.9721324 0.390 0.321 2.448979e-04 CTL_MUT
## Chn1 9.066576e-08 -0.4059544 0.413 0.431 2.719973e-04 CTL_MUT
## Bin1 1.053719e-07 -4.2383447 0.346 0.262 3.161157e-04 CTL_MUT
## Jcad 1.054109e-07 -3.3458452 0.313 0.110 3.162327e-04 CTL_MUT
## Ptprn 1.207325e-07 1.3629921 0.478 0.413 3.621974e-04 CTL_MUT
## Chka 1.308936e-07 1.2589600 0.368 0.161 3.926807e-04 CTL_MUT
## Rps24 1.323936e-07 2.5852938 0.366 0.434 3.971808e-04 CTL_MUT
## Dnm3 1.798285e-07 -1.8135488 0.385 0.263 5.394855e-04 CTL_MUT
## Nxph3 2.855308e-07 -2.0627667 0.236 0.078 8.565924e-04 CTL_MUT
## mt-Nd4l 3.525604e-07 0.4165887 0.364 0.342 1.057681e-03 CTL_MUT
## Hist1h1e 3.866029e-07 -2.4048384 0.278 0.106 1.159809e-03 CTL_MUT
## Tmem141 4.602194e-07 -3.1417828 0.275 0.110 1.380658e-03 CTL_MUT
## Ifrd1 5.531869e-07 -1.8314060 0.322 0.171 1.659561e-03 CTL_MUT
## Celf2 5.635126e-07 1.0571872 0.425 0.401 1.690538e-03 CTL_MUT
## Caln1 6.943915e-07 -0.5666486 0.377 0.228 2.083175e-03 CTL_MUT
## Gm17167 7.385233e-07 -1.1307372 0.351 0.153 2.215570e-03 CTL_MUT
## Tcf4 7.748725e-07 4.6908010 0.417 0.422 2.324617e-03 CTL_MUT
## Serinc3 9.212633e-07 1.5439271 0.329 0.141 2.763790e-03 CTL_MUT
## Nrsn1 1.079802e-06 -4.8236053 0.345 0.342 3.239407e-03 CTL_MUT
## Tubb5 1.182228e-06 1.4059957 0.387 0.435 3.546685e-03 CTL_MUT
## Lamp1 1.755412e-06 1.0676576 0.342 0.331 5.266237e-03 CTL_MUT
## Rtn1 1.829635e-06 0.5933584 0.459 0.469 5.488906e-03 CTL_MUT
## Dgkg 2.399276e-06 -2.5911589 0.329 0.126 7.197827e-03 CTL_MUT
## Cenpe 2.434415e-06 -4.3352920 0.236 0.010 7.303244e-03 CTL_MUT
## Mef2c 3.726463e-06 0.5700316 0.417 0.441 1.117939e-02 CTL_MUT
## Gm45159 4.474988e-06 -2.4758981 0.308 0.110 1.342496e-02 CTL_MUT
## Rplp1 4.753388e-06 -0.4016951 0.388 0.394 1.426016e-02 CTL_MUT
## Ttc14 5.443076e-06 4.2588823 0.381 0.267 1.632923e-02 CTL_MUT
## Nme1 5.646255e-06 -0.4119133 0.431 0.445 1.693876e-02 CTL_MUT
## Gpm6a 6.019624e-06 -0.6883934 0.411 0.411 1.805887e-02 CTL_MUT
## Rflnb 6.296788e-06 -2.6246036 0.238 0.064 1.889036e-02 CTL_MUT
## Dek 6.538356e-06 -0.6805793 0.326 0.191 1.961507e-02 CTL_MUT
## Tia1 6.688920e-06 1.4990570 0.342 0.186 2.006676e-02 CTL_MUT
## Mcl1 8.517078e-06 -3.2092128 0.292 0.149 2.555123e-02 CTL_MUT
## Scn1a 9.399766e-06 1.1606036 0.325 0.182 2.819930e-02 CTL_MUT
## Tubb4a 1.018098e-05 -0.7958893 0.354 0.358 3.054293e-02 CTL_MUT
## H3f3a 1.338647e-05 0.3623355 0.358 0.374 4.015942e-02 CTL_MUT
## Ildr2 1.494546e-05 -7.0693507 0.339 0.204 4.483639e-02 CTL_MUT
## Tra2a 1.525516e-05 0.3211472 0.411 0.243 4.576547e-02 CTL_MUT
## Ptprd 1.686173e-05 -3.4009871 0.406 0.346 5.058518e-02 CTL_MUT
## Cdkn1a 1.872714e-05 -2.2659989 0.307 0.172 5.618142e-02 CTL_MUT
## Hmgb1 2.067817e-05 -1.6857549 0.394 0.459 6.203452e-02 CTL_MUT
## Atp2b2 2.230547e-05 1.7289874 0.450 0.425 6.691640e-02 CTL_MUT
## Ncam1 2.460696e-05 4.7009529 0.380 0.393 7.382089e-02 CTL_MUT
## Slc7a14 2.600764e-05 2.9845197 0.328 0.106 7.802292e-02 CTL_MUT
## Nfasc 3.994341e-05 -3.7468712 0.350 0.176 1.198302e-01 CTL_MUT
## Ppp1r1a 4.297396e-05 0.8275725 0.336 0.261 1.289219e-01 CTL_MUT
## Fyn 4.462329e-05 -2.9665428 0.336 0.201 1.338699e-01 CTL_MUT
## Syne2 4.801303e-05 -1.5392953 0.243 0.043 1.440391e-01 CTL_MUT
## Rps4x 4.892561e-05 -2.0194908 0.357 0.414 1.467768e-01 CTL_MUT
## Gria2 5.117922e-05 2.1432358 0.449 0.400 1.535376e-01 CTL_MUT
## Pde10a 6.163046e-05 0.3174910 0.392 0.189 1.848914e-01 CTL_MUT
## Zfp704 6.578182e-05 1.3683574 0.358 0.136 1.973455e-01 CTL_MUT
## S1pr3 7.469138e-05 3.5082728 0.169 0.024 2.240741e-01 CTL_MUT
## Jun 7.607064e-05 -2.8336740 0.297 0.293 2.282119e-01 CTL_MUT
## Tmsb4x 7.817083e-05 -2.6699902 0.403 0.421 2.345125e-01 CTL_MUT
## Kcnq1ot1 8.023999e-05 -1.7001290 0.354 0.297 2.407200e-01 CTL_MUT
## Scg5 8.067266e-05 0.7592134 0.409 0.419 2.420180e-01 CTL_MUT
## Egfl7 9.371585e-05 -2.7383247 0.318 0.149 2.811475e-01 CTL_MUT
## Sv2b 1.082651e-04 2.8381707 0.398 0.347 3.247954e-01 CTL_MUT
## Epn2 1.106421e-04 0.7686826 0.326 0.164 3.319264e-01 CTL_MUT
## Kank3 1.187038e-04 -1.2027683 0.206 0.044 3.561114e-01 CTL_MUT
## Nefl 1.332202e-04 0.8687001 0.386 0.373 3.996607e-01 CTL_MUT
## Rhob 1.738313e-04 -0.4401246 0.334 0.217 5.214940e-01 CTL_MUT
## Cfl1 2.324421e-04 -0.4895166 0.413 0.425 6.973262e-01 CTL_MUT
## Fez1 2.618681e-04 1.3312405 0.372 0.401 7.856044e-01 CTL_MUT
## Olfm1 2.618681e-04 -0.3903835 0.432 0.438 7.856044e-01 CTL_MUT
## Tmem108 2.690114e-04 -2.9104081 0.321 0.121 8.070341e-01 CTL_MUT
## Map1b 3.201719e-04 -2.3658929 0.455 0.407 9.605156e-01 CTL_MUT
## Igsf21 3.577187e-04 -4.6825172 0.303 0.118 1.000000e+00 CTL_MUT
## Mir124a-1hg 3.594833e-04 -0.4720488 0.375 0.182 1.000000e+00 CTL_MUT
## Rps20 4.257949e-04 1.3835128 0.423 0.425 1.000000e+00 CTL_MUT
## Nos1ap 4.326526e-04 2.2649028 0.423 0.317 1.000000e+00 CTL_MUT
## Igf1r 4.413641e-04 -2.6793462 0.337 0.130 1.000000e+00 CTL_MUT
## Osbpl1a 4.485161e-04 -0.4128104 0.403 0.435 1.000000e+00 CTL_MUT
## Ftl1 4.982025e-04 -4.7869716 0.334 0.393 1.000000e+00 CTL_MUT
## Nktr 4.993571e-04 1.7475882 0.392 0.253 1.000000e+00 CTL_MUT
## Hmgb3 5.068717e-04 -2.1396898 0.262 0.129 1.000000e+00 CTL_MUT
## Nrxn3 5.129608e-04 -3.0329317 0.397 0.312 1.000000e+00 CTL_MUT
## Podxl 5.158798e-04 -2.9451031 0.204 0.020 1.000000e+00 CTL_MUT
## Rps18 5.237220e-04 3.9760390 0.378 0.427 1.000000e+00 CTL_MUT
## Dbf4 5.402273e-04 -5.3600002 0.269 0.009 1.000000e+00 CTL_MUT
## Inf2 5.429102e-04 2.2588026 0.319 0.123 1.000000e+00 CTL_MUT
## Cdr1os 5.686697e-04 -1.5926047 0.368 0.296 1.000000e+00 CTL_MUT
## Luc7l2 6.075971e-04 1.7405310 0.381 0.299 1.000000e+00 CTL_MUT
## Dlc1 6.189969e-04 -1.1248177 0.373 0.120 1.000000e+00 CTL_MUT
## Cpne6 6.213130e-04 -4.9558940 0.301 0.194 1.000000e+00 CTL_MUT
## Rps10 6.327535e-04 2.0961723 0.387 0.438 1.000000e+00 CTL_MUT
## Rps28 6.404607e-04 2.1266608 0.369 0.370 1.000000e+00 CTL_MUT
## Cplx2 6.652359e-04 -3.7800221 0.400 0.364 1.000000e+00 CTL_MUT
## Nap1l5 6.801125e-04 -3.8614852 0.345 0.385 1.000000e+00 CTL_MUT
## Pcsk2 7.107162e-04 1.5606242 0.430 0.403 1.000000e+00 CTL_MUT
## Sh3gl3 7.457885e-04 -3.6794840 0.293 0.108 1.000000e+00 CTL_MUT
## Ccnl1 7.527157e-04 3.1752290 0.340 0.152 1.000000e+00 CTL_MUT
## Map7 7.798718e-04 0.3890985 0.304 0.118 1.000000e+00 CTL_MUT
## Tenm2 7.844742e-04 -3.2868585 0.340 0.114 1.000000e+00 CTL_MUT
## Smarca2 8.005887e-04 0.3365286 0.353 0.287 1.000000e+00 CTL_MUT
## Ccl27a 8.263000e-04 0.6103928 0.378 0.351 1.000000e+00 CTL_MUT
## Ly6h 1.066115e-03 0.6358273 0.408 0.403 1.000000e+00 CTL_MUT
## Rprml 1.115989e-03 -0.7052930 0.402 0.407 1.000000e+00 CTL_MUT
## Ntrk2 1.121143e-03 -3.9591057 0.381 0.374 1.000000e+00 CTL_MUT
## Peg3 1.152077e-03 0.3330768 0.391 0.341 1.000000e+00 CTL_MUT
## Ybx1 1.157184e-03 1.5952241 0.354 0.347 1.000000e+00 CTL_MUT
## Timp2 1.320076e-03 2.9803277 0.333 0.281 1.000000e+00 CTL_MUT
## Il1r1 1.330849e-03 -3.4041078 0.264 0.015 1.000000e+00 CTL_MUT
## Rnd3 1.372979e-03 -3.2023834 0.281 0.056 1.000000e+00 CTL_MUT
## Neto2 1.488220e-03 3.0133586 0.326 0.160 1.000000e+00 CTL_MUT
## Syne1 1.545409e-03 0.6542791 0.383 0.382 1.000000e+00 CTL_MUT
## Aplp2 1.547175e-03 1.5176557 0.410 0.436 1.000000e+00 CTL_MUT
## Snhg14 1.580935e-03 -0.3864172 0.317 0.192 1.000000e+00 CTL_MUT
## Dock4 1.683764e-03 -1.6021695 0.357 0.139 1.000000e+00 CTL_MUT
## Atp1a3 1.699404e-03 3.1651193 0.399 0.430 1.000000e+00 CTL_MUT
## Ptma 1.707444e-03 -2.2436369 0.337 0.404 1.000000e+00 CTL_MUT
## Adgrb3 1.972541e-03 0.6205310 0.376 0.188 1.000000e+00 CTL_MUT
## Pcdh7 2.205239e-03 0.8883429 0.377 0.308 1.000000e+00 CTL_MUT
## Ier2 2.338808e-03 -2.3210899 0.279 0.136 1.000000e+00 CTL_MUT
## Rap1a 2.408746e-03 -4.5092381 0.306 0.134 1.000000e+00 CTL_MUT
## Rcan2 2.487679e-03 3.5188176 0.293 0.163 1.000000e+00 CTL_MUT
## Rian 2.503019e-03 -1.8185550 0.353 0.289 1.000000e+00 CTL_MUT
## Rpl13a 2.649359e-03 2.5637179 0.374 0.434 1.000000e+00 CTL_MUT
## Arap3 2.975090e-03 -5.1555534 0.191 0.010 1.000000e+00 CTL_MUT
## Rpl26 3.009028e-03 3.0926229 0.400 0.450 1.000000e+00 CTL_MUT
## Itgb1 3.077833e-03 -1.8969226 0.281 0.113 1.000000e+00 CTL_MUT
## App 3.245858e-03 3.3868422 0.439 0.403 1.000000e+00 CTL_MUT
## Kctd1 4.037212e-03 -5.4976288 0.324 0.152 1.000000e+00 CTL_MUT
## Kalrn 4.149942e-03 1.9888572 0.396 0.287 1.000000e+00 CTL_MUT
## Btbd3 4.483511e-03 1.6687353 0.287 0.139 1.000000e+00 CTL_MUT
## Syt11 4.696303e-03 0.5349937 0.461 0.454 1.000000e+00 CTL_MUT
## B830012L14Rik 4.939328e-03 -0.6026382 0.320 0.112 1.000000e+00 CTL_MUT
## Itga4 5.056489e-03 0.3859724 0.260 0.040 1.000000e+00 CTL_MUT
## Syt1 5.088775e-03 3.3939336 0.481 0.470 1.000000e+00 CTL_MUT
## Pgm2l1 6.035867e-03 4.4628173 0.418 0.399 1.000000e+00 CTL_MUT
## Jund 6.120863e-03 -1.8559570 0.362 0.386 1.000000e+00 CTL_MUT
## Slc9a3r2 6.226031e-03 -2.4083864 0.281 0.094 1.000000e+00 CTL_MUT
## Etnk1 7.621085e-03 2.8091968 0.409 0.284 1.000000e+00 CTL_MUT
## Josd2 7.817043e-03 -1.0664416 0.295 0.134 1.000000e+00 CTL_MUT
## Sox4 8.298459e-03 -0.6301573 0.278 0.162 1.000000e+00 CTL_MUT
## Dusp1 8.500135e-03 -0.9390410 0.280 0.160 1.000000e+00 CTL_MUT
## Sorl1 8.538982e-03 1.0673676 0.373 0.297 1.000000e+00 CTL_MUT
## Ccnd2 9.170729e-03 -1.9621834 0.374 0.261 1.000000e+00 CTL_MUT
## Atp1a1 9.819552e-03 -5.0861714 0.382 0.415 1.000000e+00 CTL_MUT
## Kcnk9 1.041134e-02 1.0322869 0.335 0.124 1.000000e+00 CTL_MUT
## Rpl7 1.048577e-02 1.4910887 0.376 0.392 1.000000e+00 CTL_MUT
## H2afv 1.072643e-02 -3.3230950 0.305 0.138 1.000000e+00 CTL_MUT
## Lrp1b 1.114761e-02 -3.1066249 0.340 0.215 1.000000e+00 CTL_MUT
## Abcc5 1.152595e-02 0.6685088 0.358 0.202 1.000000e+00 CTL_MUT
## Mat2a 1.305334e-02 3.7839640 0.366 0.290 1.000000e+00 CTL_MUT
## Pakap.1 1.325783e-02 -3.2348667 0.307 0.117 1.000000e+00 CTL_MUT
## Celf4 1.447176e-02 -1.9188149 0.421 0.439 1.000000e+00 CTL_MUT
## Rpl11 1.468587e-02 2.8097253 0.409 0.445 1.000000e+00 CTL_MUT
## Chgb 1.657078e-02 -0.5477326 0.365 0.369 1.000000e+00 CTL_MUT
## Rasgrp1 1.663221e-02 0.7995205 0.400 0.303 1.000000e+00 CTL_MUT
## Lrp8 1.789362e-02 2.9646548 0.368 0.162 1.000000e+00 CTL_MUT
## Selenom 2.028136e-02 -9.0542268 0.368 0.347 1.000000e+00 CTL_MUT
## mt-Nd5 2.120023e-02 0.6003934 0.388 0.397 1.000000e+00 CTL_MUT
## Fam114a1 2.185225e-02 -3.3930372 0.235 0.010 1.000000e+00 CTL_MUT
## Nudt4 2.226587e-02 -4.7297320 0.309 0.206 1.000000e+00 CTL_MUT
## Rpl21 2.237020e-02 1.0994230 0.409 0.419 1.000000e+00 CTL_MUT
## Chl1 2.318156e-02 3.8691131 0.383 0.226 1.000000e+00 CTL_MUT
## Slc8a1 2.494760e-02 -0.7263209 0.405 0.308 1.000000e+00 CTL_MUT
## Cd24a 2.546024e-02 -3.5275853 0.205 0.052 1.000000e+00 CTL_MUT
## Afap1l1 2.947494e-02 -1.9612245 0.230 0.045 1.000000e+00 CTL_MUT
## Wnk1 3.137226e-02 2.6347549 0.355 0.189 1.000000e+00 CTL_MUT
## Gm26871 3.162417e-02 -2.7913306 0.341 0.098 1.000000e+00 CTL_MUT
## Rpl38 3.170614e-02 3.6269514 0.445 0.446 1.000000e+00 CTL_MUT
## Lmo4 3.191617e-02 -0.4316012 0.418 0.377 1.000000e+00 CTL_MUT
## Eef1a1 3.451069e-02 2.6188154 0.387 0.405 1.000000e+00 CTL_MUT
## Snhg11 3.602173e-02 -1.6283618 0.403 0.395 1.000000e+00 CTL_MUT
## Lats2 3.688315e-02 -0.9398200 0.229 0.029 1.000000e+00 CTL_MUT
## Pitpnc1 3.708216e-02 1.1878237 0.322 0.150 1.000000e+00 CTL_MUT
## Ctxn1 3.830763e-02 0.2901270 0.444 0.433 1.000000e+00 CTL_MUT
## Ogfrl1 4.174758e-02 0.5363447 0.401 0.284 1.000000e+00 CTL_MUT
## Egr1 4.240050e-02 -2.3751426 0.396 0.336 1.000000e+00 CTL_MUT
## Rps29 4.307454e-02 -3.1100440 0.350 0.376 1.000000e+00 CTL_MUT
## Rpl18a 4.320903e-02 1.3554127 0.367 0.412 1.000000e+00 CTL_MUT
## Tfrc 4.688816e-02 2.8139541 0.326 0.153 1.000000e+00 CTL_MUT
## Zcchc7 4.791185e-02 1.8147197 0.346 0.158 1.000000e+00 CTL_MUT
## Xist 5.212186e-02 -1.0192056 0.372 0.361 1.000000e+00 CTL_MUT
## Fau 5.294606e-02 -1.2575284 0.397 0.399 1.000000e+00 CTL_MUT
## Rps8 5.520646e-02 0.6802305 0.395 0.403 1.000000e+00 CTL_MUT
## R3hdm1 6.321185e-02 -0.3927033 0.369 0.363 1.000000e+00 CTL_MUT
## Mical2 6.956195e-02 -0.5533700 0.368 0.254 1.000000e+00 CTL_MUT
## Gng2 7.371062e-02 0.4652395 0.360 0.265 1.000000e+00 CTL_MUT
## Opcml 7.478522e-02 -2.2504077 0.419 0.376 1.000000e+00 CTL_MUT
## Map1lc3a 7.509354e-02 -0.3413303 0.437 0.417 1.000000e+00 CTL_MUT
## Tspyl4 7.607153e-02 -0.3499194 0.409 0.392 1.000000e+00 CTL_MUT
## Adcy1 7.982168e-02 -3.1821425 0.392 0.238 1.000000e+00 CTL_MUT
## Rpl8 8.539945e-02 3.0390786 0.445 0.443 1.000000e+00 CTL_MUT
## Syt7 8.706796e-02 1.6348495 0.391 0.224 1.000000e+00 CTL_MUT
## Rack1 8.720902e-02 2.1189201 0.382 0.348 1.000000e+00 CTL_MUT
## Tsc22d1 9.721420e-02 1.2148915 0.403 0.411 1.000000e+00 CTL_MUT
## Camk2a 9.854502e-02 0.2602666 0.401 0.423 1.000000e+00 CTL_MUT
## Igsf9b 1.005634e-01 -2.5657917 0.360 0.137 1.000000e+00 CTL_MUT
## Reep5 1.010063e-01 0.2704119 0.379 0.364 1.000000e+00 CTL_MUT
## Srgap2 1.023953e-01 -0.5723470 0.342 0.166 1.000000e+00 CTL_MUT
## Rps14 1.030190e-01 2.4712114 0.400 0.400 1.000000e+00 CTL_MUT
## Mast4 1.050270e-01 0.8696371 0.372 0.164 1.000000e+00 CTL_MUT
## Rps16 1.050722e-01 3.2685547 0.398 0.446 1.000000e+00 CTL_MUT
## Rpl13 1.123328e-01 1.6686389 0.364 0.374 1.000000e+00 CTL_MUT
## Lsamp 1.200400e-01 1.0124509 0.395 0.312 1.000000e+00 CTL_MUT
## Sorbs2 1.228716e-01 -0.8102071 0.382 0.308 1.000000e+00 CTL_MUT
## H2afj 1.282487e-01 -3.3594190 0.412 0.380 1.000000e+00 CTL_MUT
## Auts2 1.370380e-01 -0.9655592 0.402 0.320 1.000000e+00 CTL_MUT
## Apc 1.411028e-01 -8.1500953 0.362 0.272 1.000000e+00 CTL_MUT
## Syn2 1.557451e-01 -1.3623794 0.415 0.428 1.000000e+00 CTL_MUT
## Rps5 1.609516e-01 1.4270859 0.372 0.421 1.000000e+00 CTL_MUT
## Fam107b 1.809541e-01 -2.4880724 0.284 0.011 1.000000e+00 CTL_MUT
## Pnmal2 1.818198e-01 0.3042144 0.373 0.318 1.000000e+00 CTL_MUT
## Nrxn1 1.870263e-01 0.2966525 0.435 0.447 1.000000e+00 CTL_MUT
## Phip 1.925398e-01 -2.0875858 0.383 0.180 1.000000e+00 CTL_MUT
## Slc39a10 2.351514e-01 2.6063956 0.413 0.325 1.000000e+00 CTL_MUT
## Desi1 2.361627e-01 -2.9796634 0.307 0.137 1.000000e+00 CTL_MUT
## Ctsb 2.555265e-01 -2.1785085 0.395 0.389 1.000000e+00 CTL_MUT
## H3f3b 2.585093e-01 -2.9126453 0.374 0.394 1.000000e+00 CTL_MUT
## Arl4a 2.603083e-01 -2.6308814 0.327 0.194 1.000000e+00 CTL_MUT
## Ap1s2 2.609899e-01 -2.4771841 0.290 0.120 1.000000e+00 CTL_MUT
## Cit 2.611976e-01 -1.5829091 0.374 0.274 1.000000e+00 CTL_MUT
## Pnisr 2.781490e-01 1.6911525 0.375 0.320 1.000000e+00 CTL_MUT
## Csmd1 2.810538e-01 -2.3322133 0.356 0.151 1.000000e+00 CTL_MUT
## Rpl27a 2.883526e-01 1.8653032 0.407 0.435 1.000000e+00 CTL_MUT
## Gria3 2.905983e-01 1.0815702 0.370 0.339 1.000000e+00 CTL_MUT
## Sh3glb1 3.193099e-01 3.1812735 0.353 0.211 1.000000e+00 CTL_MUT
## D10Wsu102e 3.199455e-01 -2.0118697 0.383 0.174 1.000000e+00 CTL_MUT
## Rpl41 3.277644e-01 1.2671551 0.432 0.420 1.000000e+00 CTL_MUT
## Ahi1 3.311932e-01 2.1076123 0.379 0.325 1.000000e+00 CTL_MUT
## Miat 3.348230e-01 0.7221590 0.355 0.178 1.000000e+00 CTL_MUT
## Crip2 3.363516e-01 0.5675499 0.407 0.420 1.000000e+00 CTL_MUT
## Mcf2l 3.385780e-01 2.7518259 0.374 0.130 1.000000e+00 CTL_MUT
## Rps27a 3.391089e-01 2.6607141 0.399 0.423 1.000000e+00 CTL_MUT
## Tmsb10 3.412285e-01 -1.6336963 0.391 0.355 1.000000e+00 CTL_MUT
## Plekha1 3.452842e-01 -6.1973359 0.341 0.152 1.000000e+00 CTL_MUT
## Dpysl3 3.504009e-01 -0.7420622 0.273 0.127 1.000000e+00 CTL_MUT
## Rps7 3.539793e-01 2.6703288 0.413 0.442 1.000000e+00 CTL_MUT
## 9530059O14Rik 3.606950e-01 3.2461848 0.350 0.167 1.000000e+00 CTL_MUT
## Rps11 3.659208e-01 1.9431253 0.401 0.445 1.000000e+00 CTL_MUT
## Sez6 3.865830e-01 3.8670970 0.348 0.157 1.000000e+00 CTL_MUT
## Ttc9b 4.012030e-01 -0.2595458 0.414 0.384 1.000000e+00 CTL_MUT
## Pbx1 4.138669e-01 -5.5298406 0.390 0.283 1.000000e+00 CTL_MUT
## Gria1 4.425762e-01 0.6568745 0.379 0.288 1.000000e+00 CTL_MUT
## Naalad2 4.428779e-01 1.6261279 0.237 0.056 1.000000e+00 CTL_MUT
## Daam1 4.532208e-01 -4.5927984 0.303 0.145 1.000000e+00 CTL_MUT
## Mir100hg 4.614956e-01 0.6710612 0.349 0.179 1.000000e+00 CTL_MUT
## Hmgn1 5.307182e-01 -3.0355942 0.328 0.217 1.000000e+00 CTL_MUT
## Efr3a 5.412749e-01 -2.4131417 0.337 0.171 1.000000e+00 CTL_MUT
## Sept7 5.448707e-01 0.5880072 0.418 0.412 1.000000e+00 CTL_MUT
## Ppp3ca 5.455184e-01 0.3655182 0.443 0.409 1.000000e+00 CTL_MUT
## Efhd2 5.563225e-01 0.2968747 0.342 0.269 1.000000e+00 CTL_MUT
## Slc38a2 5.641845e-01 2.9311871 0.364 0.174 1.000000e+00 CTL_MUT
## Shank1 5.723472e-01 2.5373969 0.378 0.255 1.000000e+00 CTL_MUT
## Epha5 6.040823e-01 3.8893358 0.419 0.416 1.000000e+00 CTL_MUT
## Ntrk3 6.065161e-01 3.1204624 0.369 0.185 1.000000e+00 CTL_MUT
## Myl6 6.260205e-01 -3.3885497 0.432 0.409 1.000000e+00 CTL_MUT
## Gnb4 6.266222e-01 -1.5680358 0.320 0.160 1.000000e+00 CTL_MUT
## Rpsa 6.412655e-01 -1.7784745 0.377 0.414 1.000000e+00 CTL_MUT
## Enah 6.429547e-01 3.8349069 0.370 0.192 1.000000e+00 CTL_MUT
## Tenm1 6.438788e-01 -4.3757850 0.377 0.182 1.000000e+00 CTL_MUT
## Map1a 6.470839e-01 1.4829535 0.405 0.378 1.000000e+00 CTL_MUT
## Ina 6.507645e-01 1.5836879 0.389 0.334 1.000000e+00 CTL_MUT
## Ly6e 6.772992e-01 -1.8455608 0.392 0.322 1.000000e+00 CTL_MUT
## Gpx3 6.837798e-01 -3.0927253 0.226 0.027 1.000000e+00 CTL_MUT
## Dclk1 6.893108e-01 -1.9029069 0.396 0.415 1.000000e+00 CTL_MUT
## Rpl32 7.089254e-01 2.8606048 0.396 0.430 1.000000e+00 CTL_MUT
## Ogt 7.201927e-01 -0.4230934 0.378 0.244 1.000000e+00 CTL_MUT
## Tenm4 7.227120e-01 1.8210286 0.374 0.185 1.000000e+00 CTL_MUT
## Zeb2 7.535264e-01 -1.3627490 0.390 0.343 1.000000e+00 CTL_MUT
## Rps9 7.620949e-01 -1.9700013 0.379 0.412 1.000000e+00 CTL_MUT
## AC149090.1 7.822878e-01 -5.1310919 0.412 0.121 1.000000e+00 CTL_MUT
## Rps12 7.827225e-01 -1.2685938 0.368 0.396 1.000000e+00 CTL_MUT
## Macf1 7.834024e-01 -0.8623586 0.375 0.318 1.000000e+00 CTL_MUT
## Arpp21 7.882419e-01 2.4149870 0.432 0.435 1.000000e+00 CTL_MUT
## Bsg 8.534879e-01 -1.3734197 0.298 0.302 1.000000e+00 CTL_MUT
## Nfib 8.545910e-01 1.0328693 0.400 0.292 1.000000e+00 CTL_MUT
## Epha4 8.997275e-01 1.7312262 0.385 0.295 1.000000e+00 CTL_MUT
## Atp2b4 9.019931e-01 -2.3088582 0.342 0.170 1.000000e+00 CTL_MUT
## Pcdh17 9.028718e-01 -2.2591703 0.377 0.228 1.000000e+00 CTL_MUT
## Cadm2 9.114870e-01 0.7828442 0.428 0.422 1.000000e+00 CTL_MUT
## Slc24a2 9.118147e-01 -2.3346014 0.391 0.319 1.000000e+00 CTL_MUT
## H2afz 9.264167e-01 -2.4708068 0.403 0.430 1.000000e+00 CTL_MUT
## Rpl18 9.407934e-01 2.7227921 0.399 0.430 1.000000e+00 CTL_MUT
## Ano3 9.410543e-01 -2.6893136 0.323 0.169 1.000000e+00 CTL_MUT
## Rpl23 9.753457e-01 4.1847685 0.415 0.444 1.000000e+00 CTL_MUT
## Rpl10 9.826408e-01 2.9017067 0.398 0.428 1.000000e+00 CTL_MUT
## Cdc37l1 9.920484e-01 4.2326468 0.377 0.230 1.000000e+00 CTL_MUTDifferential expression Analysis for cluster between groups
Next we will do DEG for each cluster betweent the two groups, and write the results to a csv file
Quatitative analysis of DEGs by each cluster
MAPK pathway gene plotting
Because we are interested in the MAPK1 pathway, we
select relevant genes for plotting
session info
Print session information
## R version 4.2.1 (2022-06-23 ucrt)
## Platform: x86_64-w64-mingw32/x64 (64-bit)
## Running under: Windows 10 x64 (build 18363)
##
## Matrix products: default
##
## locale:
## [1] LC_COLLATE=English_United States.utf8
## [2] LC_CTYPE=English_United States.utf8
## [3] LC_MONETARY=English_United States.utf8
## [4] LC_NUMERIC=C
## [5] LC_TIME=English_United States.utf8
##
## attached base packages:
## [1] grid stats4 stats graphics grDevices utils datasets
## [8] methods base
##
## other attached packages:
## [1] celldex_1.6.0 SingleR_1.10.0
## [3] patchwork_1.1.1 circlize_0.4.15
## [5] RColorBrewer_1.1-3 ComplexHeatmap_2.12.0
## [7] SingleCellExperiment_1.18.0 SummarizedExperiment_1.26.1
## [9] Biobase_2.56.0 GenomicRanges_1.48.0
## [11] GenomeInfoDb_1.32.2 IRanges_2.30.0
## [13] S4Vectors_0.34.0 BiocGenerics_0.42.0
## [15] MatrixGenerics_1.8.1 matrixStats_0.62.0
## [17] rstatix_0.7.0 ggplot2_3.3.6.9000
## [19] cowplot_1.1.1 dplyr_1.0.9
## [21] sp_1.5-0 SeuratObject_4.1.0
## [23] Seurat_4.1.1
##
## loaded via a namespace (and not attached):
## [1] utf8_1.2.2 reticulate_1.25
## [3] tidyselect_1.1.2 RSQLite_2.2.14
## [5] AnnotationDbi_1.58.0 htmlwidgets_1.5.4
## [7] BiocParallel_1.30.3 Rtsne_0.16
## [9] munsell_0.5.0 ScaledMatrix_1.4.0
## [11] codetools_0.2-18 ica_1.0-2
## [13] future_1.26.1 miniUI_0.1.1.1
## [15] withr_2.5.0 spatstat.random_2.2-0
## [17] colorspace_2.0-3 progressr_0.10.1
## [19] filelock_1.0.2 highr_0.9
## [21] knitr_1.39 rstudioapi_0.13
## [23] ROCR_1.0-11 tensor_1.5
## [25] listenv_0.8.0 labeling_0.4.2
## [27] GenomeInfoDbData_1.2.8 polyclip_1.10-0
## [29] pheatmap_1.0.12 bit64_4.0.5
## [31] farver_2.1.0 parallelly_1.32.0
## [33] vctrs_0.4.1 generics_0.1.3
## [35] xfun_0.31 BiocFileCache_2.4.0
## [37] R6_2.5.1 doParallel_1.0.17
## [39] clue_0.3-61 rsvd_1.0.5
## [41] cachem_1.0.6 bitops_1.0-7
## [43] spatstat.utils_2.3-1 DelayedArray_0.22.0
## [45] assertthat_0.2.1 promises_1.2.0.1
## [47] scales_1.2.0 rgeos_0.5-9
## [49] gtable_0.3.0 beachmat_2.12.0
## [51] globals_0.15.1 goftest_1.2-3
## [53] rlang_1.0.3 GlobalOptions_0.1.2
## [55] splines_4.2.1 lazyeval_0.2.2
## [57] spatstat.geom_2.4-0 broom_1.0.0
## [59] BiocManager_1.30.18 yaml_2.3.5
## [61] reshape2_1.4.4 abind_1.4-5
## [63] backports_1.4.1 httpuv_1.6.5
## [65] tools_4.2.1 ellipsis_0.3.2
## [67] spatstat.core_2.4-4 jquerylib_0.1.4
## [69] ggridges_0.5.3 Rcpp_1.0.9
## [71] plyr_1.8.7 sparseMatrixStats_1.8.0
## [73] zlibbioc_1.42.0 purrr_0.3.4
## [75] RCurl_1.98-1.7 rpart_4.1.16
## [77] deldir_1.0-6 viridis_0.6.2
## [79] pbapply_1.5-0 GetoptLong_1.0.5
## [81] zoo_1.8-10 ggrepel_0.9.1
## [83] cluster_2.1.3 magrittr_2.0.3
## [85] data.table_1.14.2 RSpectra_0.16-1
## [87] scattermore_0.8 lmtest_0.9-40
## [89] RANN_2.6.1 fitdistrplus_1.1-8
## [91] mime_0.12 evaluate_0.15
## [93] xtable_1.8-4 gridExtra_2.3
## [95] shape_1.4.6 compiler_4.2.1
## [97] tibble_3.1.7 KernSmooth_2.23-20
## [99] crayon_1.5.1 htmltools_0.5.2
## [101] mgcv_1.8-40 later_1.3.0
## [103] tidyr_1.2.0 DBI_1.1.3
## [105] ExperimentHub_2.4.0 dbplyr_2.2.1
## [107] rappdirs_0.3.3 MASS_7.3-58
## [109] Matrix_1.4-1 car_3.1-0
## [111] cli_3.3.0 parallel_4.2.1
## [113] igraph_1.3.2 pkgconfig_2.0.3
## [115] plotly_4.10.0.9001 spatstat.sparse_2.1-1
## [117] foreach_1.5.2 bslib_0.3.1
## [119] XVector_0.36.0 stringr_1.4.0
## [121] digest_0.6.29 sctransform_0.3.3
## [123] RcppAnnoy_0.0.19 Biostrings_2.64.0
## [125] spatstat.data_2.2-0 rmarkdown_2.14
## [127] leiden_0.4.2 uwot_0.1.11
## [129] DelayedMatrixStats_1.18.0 curl_4.3.2
## [131] shiny_1.7.1 rjson_0.2.21
## [133] lifecycle_1.0.1 nlme_3.1-158
## [135] jsonlite_1.8.0 carData_3.0-5
## [137] BiocNeighbors_1.14.0 viridisLite_0.4.0
## [139] limma_3.52.2 fansi_1.0.3
## [141] pillar_1.8.0 lattice_0.20-45
## [143] KEGGREST_1.36.2 fastmap_1.1.0
## [145] httr_1.4.3 survival_3.3-1
## [147] interactiveDisplayBase_1.34.0 glue_1.6.2
## [149] png_0.1-7 iterators_1.0.14
## [151] BiocVersion_3.15.2 bit_4.0.4
## [153] stringi_1.7.6 sass_0.4.1
## [155] blob_1.2.3 AnnotationHub_3.4.0
## [157] BiocSingular_1.12.0 memoise_2.0.1
## [159] irlba_2.3.5 future.apply_1.9.0