Cargo una base de datos en que ya incluí tus modelos de resultados.
dirname(rstudioapi::getSourceEditorContext()$path)## [1] "E:/Mi unidad/Alvacast/SISTRAT 2019 (github)/jose_stata"load(paste0(dirname(rstudioapi::getSourceEditorContext()$path),"/imputed_ags_marzo_2022.RData"))
print("Lista de objetos de la base")## [1] "Lista de objetos de la base"ls()## [1] "aggr_plot" "aic1" "aic2" "aic3" "aic4"
## [6] "ci.boot" "ci_gt_imp" "ci_gt_raw" "ci_tt_imp" "ci_tt_raw"
## [11] "CIS1" "CIS2" "CIS3" "cpdata" "i"
## [16] "imp" "imp_plot" "micedata" "miss" "path"
## [21] "pwp_gt_imp" "pwp_gt_imp_2" "pwp_gt_raw" "pwp_gt_raw_2" "pwp_tt_imp"
## [26] "pwp_tt_imp_2" "pwp_tt_raw" "pwp_tt_raw_2" "rfimp" "tab_int_ci"devtools::unload("future")
unloadNamespace("future")#This package implements weighted estimation in Cox regression as proposed by Schemper, Wakounig and Heinze (Statistics in Medicine, 2009, doi: 10.1002/sim.3623). Weighted Cox regression provides unbiased average hazard ratio estimates also in case of non-proportional hazards. The package provides options to estimate time-dependent effects conveniently by including interactions of covariates with arbitrary functions of time, with or without making use of the weighting option. For more details we refer to Dunkler, Ploner, Schemper and Heinze (Journal of Statistical Software, 2018, doi: 10.18637/jss.v084.i02).
rfimp2<-rfimp #%>% dplyr::filter(id%in% c(1:100))
## ignore non-proportional hazards and apply a Cox proportional hazards model
# system.time({
# pwp_gt_imp2 <- coxphw(Surv(tstart2,tstop2,status==1) ~ terap_dis*strata(event) + sex + edad_inicio + es_conyugal + sus+ escolaridad + compromiso_biopsicosocial + tipo_programa + estatus_ocupacional +
# freq_cons + edad_al_ing+ cluster(id)+ strata(event), data = rfimp2, template = "PH",
# robust = TRUE)
# })
# system.time({
# pwp_tt_imp2 <- coxphw(Surv(tstart,tstop,status==1) ~ terap_dis*strata(event) + sex + edad_inicio + es_conyugal + sus+ escolaridad + compromiso_biopsicosocial + tipo_programa + estatus_ocupacional +
# freq_cons + edad_al_ing+ cluster(id)+ strata(event), data = rfimp2, template = "PH",
# robust = TRUE)
# })
system.time({
pwp_gt_imp2_cl <- coxphw(Surv(tstart2,tstop2,status==1) ~ terap_dis*strata(event) + sex + edad_inicio + es_conyugal + sus+ escolaridad + compromiso_biopsicosocial + tipo_programa + estatus_ocupacional +
freq_cons + edad_al_ing+ strata(event), data = rfimp2, template = "PH",
robust = TRUE, clusterid=rfimp2$id)
})## user system elapsed
## 928.94 1.42 937.62system.time({
pwp_tt_imp2_cl <- coxphw(Surv(tstart,tstop,status==1) ~ terap_dis*strata(event) + sex + edad_inicio + es_conyugal + sus+ escolaridad + compromiso_biopsicosocial + tipo_programa + estatus_ocupacional +
freq_cons + edad_al_ing+ strata(event), data = rfimp2, template = "PH",
robust = TRUE, clusterid=rfimp2$id)
})## user system elapsed
## 34436.83 38.77 34725.49# system.time({
# pwp_gt_imp3<-
# coxphw(Surv(tstart2,tstop2,status==1) ~ terap_dis*strata(event) + sex + edad_inicio + es_conyugal + sus+
# escolaridad + compromiso_biopsicosocial + tipo_programa + estatus_ocupacional +
# freq_cons + edad_al_ing+ cluster(id)+ strata(event), data = rfimp2,template="AHR", robust=T)#
# })
# system.time({
# pwp_tt_imp3<-
# coxphw(Surv(tstart,tstop,status==1) ~ terap_dis*strata(event) + sex + edad_inicio + es_conyugal + sus+
# escolaridad + compromiso_biopsicosocial + tipo_programa + estatus_ocupacional +
# freq_cons + edad_al_ing+ cluster(id)+ strata(event), data = rfimp2, template="AHR", robust=T)#
# })
system.time({
pwp_gt_imp3_cl<-
coxphw(Surv(tstart2,tstop2,status==1) ~ terap_dis*strata(event) + sex + edad_inicio + es_conyugal + sus+
escolaridad + compromiso_biopsicosocial + tipo_programa + estatus_ocupacional +
freq_cons + edad_al_ing+ strata(event), data = rfimp2, template="AHR", robust=T, clusterid=rfimp2$id)#
})## user system elapsed
## 1026.92 34.75 1070.78system.time({
pwp_tt_imp3_cl<-
coxphw(Surv(tstart,tstop,status==1) ~ terap_dis*strata(event) + sex + edad_inicio + es_conyugal + sus+
escolaridad + compromiso_biopsicosocial + tipo_programa + estatus_ocupacional +
freq_cons + edad_al_ing+ strata(event), data = rfimp2, template="AHR", robust=T, clusterid=rfimp2$id)#
})## user system elapsed
## 27506.86 38.00 27585.17Por ahora sólo puedo hacer los modelos con la base de datos en format Gap-Time. Pero creo que te puede servir para comparar. **Me llamó la atención que los modelos sin especificar cluster del PWP Cox normal, tienen diferencias mínimas en los valores de significancia SE’s.
# res_gt_2 <- cbind.data.frame(HR=round(exp(pwp_gt_imp2$coeff),2),
# Lo_ci95=round(exp(confint(pwp_gt_imp2))[,1],2),
# Up_ci95=round(exp(confint(pwp_gt_imp2))[,2],2),
# p=round(summary(pwp_gt_imp2)$prob,4)) %>%
# data.table::data.table(keep.rownames=T)
res_gt_2_cl <- cbind.data.frame(HR=round(exp(pwp_gt_imp2_cl$coeff),2),
Lo_ci95=round(exp(confint(pwp_gt_imp2_cl))[,1],2),
Up_ci95=round(exp(confint(pwp_gt_imp2_cl))[,2],2),
p=round(summary(pwp_gt_imp2_cl)$prob,4)) %>%
data.table::data.table(keep.rownames=T)## coxphw(formula = Surv(tstart2, tstop2, status == 1) ~ terap_dis *
## strata(event) + sex + edad_inicio + es_conyugal + sus + escolaridad +
## compromiso_biopsicosocial + tipo_programa + estatus_ocupacional +
## freq_cons + edad_al_ing + strata(event), data = rfimp2, template = "PH",
## robust = TRUE, clusterid = rfimp2$id)
##
## Model fitted by unweighted estimation (PH template)
##
## coef se(coef)
## terap_disTerapeutic discharge -0.2284412237 0.018794894
## strata(event)event=2 0.4874201801 0.018549484
## strata(event)event=3 0.7483486977 0.032787369
## sexF 0.1892436464 0.018794285
## edad_inicio -0.0100609167 0.001547428
## es_conyugalSeparated 0.0008915151 0.023685431
## es_conyugalSingle -0.0378879591 0.015475948
## es_conyugalWidower -0.1036464241 0.071569907
## susCocaine 0.1682216515 0.021660402
## susMarijuana -0.1274923323 0.033550558
## susOther -0.0175400235 0.056955652
## susCocaine paste 0.3274964986 0.018428518
## escolaridadSecundaria o menor -0.0868803670 0.018010831
## escolaridadPrimaria o menor -0.2540699948 0.021031063
## compromiso_biopsicosocialModerate 0.0680781175 0.027958329
## compromiso_biopsicosocialSevere 0.2702881260 0.029990113
## tipo_programaEM 0.2382077708 0.023267577
## estatus_ocupacional2 -0.0955582179 0.015869671
## estatus_ocupacional3 -0.0420560287 0.018868329
## freq_cons2 0.0509701306 0.067010050
## freq_cons3 0.0800798317 0.062110272
## freq_cons4 0.1101877021 0.057472361
## freq_cons5 0.1188327767 0.058380374
## freq_cons6 0.1312672964 0.057000558
## edad_al_ing -0.0084977456 0.000801105
## terap_disTerapeutic discharge:strata(event)event=2 0.0073263524 0.041109964
## terap_disTerapeutic discharge:strata(event)event=3 0.0388240224 0.072281845
## exp(coef) lower 0.95
## terap_disTerapeutic discharge 0.7957731 0.7669923
## strata(event)event=2 1.6281106 1.5699815
## strata(event)event=3 2.1135071 1.9819608
## sexF 1.2083353 1.1646348
## edad_inicio 0.9899895 0.9869915
## es_conyugalSeparated 1.0008919 0.9554899
## es_conyugalSingle 0.9628208 0.9340547
## es_conyugalWidower 0.9015440 0.7835496
## susCocaine 1.1831988 1.1340191
## susMarijuana 0.8803002 0.8242757
## susOther 0.9826129 0.8788236
## susCocaine paste 1.3874902 1.3382694
## escolaridadSecundaria o menor 0.9167868 0.8849882
## escolaridadPrimaria o menor 0.7756375 0.7443156
## compromiso_biopsicosocialModerate 1.0704489 1.0133694
## compromiso_biopsicosocialSevere 1.3103419 1.2355406
## tipo_programaEM 1.2689728 1.2124028
## estatus_ocupacional2 0.9088654 0.8810312
## estatus_ocupacional3 0.9588161 0.9240055
## freq_cons2 1.0522915 0.9227775
## freq_cons3 1.0833736 0.9592015
## freq_cons4 1.1164876 0.9975470
## freq_cons5 1.1261816 1.0044191
## freq_cons6 1.1402725 1.0197406
## edad_al_ing 0.9915383 0.9899826
## terap_disTerapeutic discharge:strata(event)event=2 1.0073533 0.9293706
## terap_disTerapeutic discharge:strata(event)event=3 1.0395875 0.9022661
## upper 0.95 z
## terap_disTerapeutic discharge 0.8256338 -12.15442976
## strata(event)event=2 1.6883918 26.27675132
## strata(event)event=3 2.2537844 22.82429858
## sexF 1.2536757 10.06921217
## edad_inicio 0.9929966 -6.50170258
## es_conyugalSeparated 1.0484513 0.03763981
## es_conyugalSingle 0.9924728 -2.44818342
## es_conyugalWidower 1.0373071 -1.44818441
## susCocaine 1.2345114 7.76632185
## susMarijuana 0.9401325 -3.80000627
## susOther 1.0986597 -0.30795931
## susCocaine paste 1.4385213 17.77117947
## escolaridadSecundaria o menor 0.9497279 -4.82378446
## escolaridadPrimaria o menor 0.8082775 -12.08070176
## compromiso_biopsicosocialModerate 1.1307436 2.43498521
## compromiso_biopsicosocialSevere 1.3896719 9.01257433
## tipo_programaEM 1.3281824 10.23775590
## estatus_ocupacional2 0.9375790 -6.02143678
## estatus_ocupacional3 0.9949381 -2.22892171
## freq_cons2 1.1999830 0.76063412
## freq_cons3 1.2236201 1.28931703
## freq_cons4 1.2496099 1.91722943
## freq_cons5 1.2627050 2.03549188
## freq_cons6 1.2750512 2.30291248
## edad_al_ing 0.9930963 -10.60752980
## terap_disTerapeutic discharge:strata(event)event=2 1.0918794 0.17821354
## terap_disTerapeutic discharge:strata(event)event=3 1.1978087 0.53711997
## p
## terap_disTerapeutic discharge 0.000000e+00
## strata(event)event=2 0.000000e+00
## strata(event)event=3 0.000000e+00
## sexF 0.000000e+00
## edad_inicio 7.941603e-11
## es_conyugalSeparated 9.699749e-01
## es_conyugalSingle 1.435785e-02
## es_conyugalWidower 1.475655e-01
## susCocaine 8.104628e-15
## susMarijuana 1.446924e-04
## susOther 7.581133e-01
## susCocaine paste 0.000000e+00
## escolaridadSecundaria o menor 1.408596e-06
## escolaridadPrimaria o menor 0.000000e+00
## compromiso_biopsicosocialModerate 1.489240e-02
## compromiso_biopsicosocialSevere 0.000000e+00
## tipo_programaEM 0.000000e+00
## estatus_ocupacional2 1.728755e-09
## estatus_ocupacional3 2.581911e-02
## freq_cons2 4.468756e-01
## freq_cons3 1.972879e-01
## freq_cons4 5.520879e-02
## freq_cons5 4.180140e-02
## freq_cons6 2.128377e-02
## edad_al_ing 0.000000e+00
## terap_disTerapeutic discharge:strata(event)event=2 8.585553e-01
## terap_disTerapeutic discharge:strata(event)event=3 5.911847e-01
##
## Wald Chi-square = 5307.468 on 27 df p = 0 n = 107665
##
## Covariance-Matrix:
## terap_disTerapeutic discharge
## terap_disTerapeutic discharge 3.532481e-04
## strata(event)event=2 7.375441e-05
## strata(event)event=3 7.199970e-05
## sexF -5.796489e-06
## edad_inicio -2.552394e-07
## es_conyugalSeparated -2.686681e-07
## es_conyugalSingle 5.526680e-06
## es_conyugalWidower 1.957091e-05
## susCocaine 1.972562e-05
## susMarijuana 3.620392e-06
## susOther -1.439125e-05
## susCocaine paste 2.353810e-05
## escolaridadSecundaria o menor 1.961346e-05
## escolaridadPrimaria o menor 3.106026e-05
## compromiso_biopsicosocialModerate 1.808933e-05
## compromiso_biopsicosocialSevere 1.721497e-05
## tipo_programaEM -9.381193e-06
## estatus_ocupacional2 -2.112481e-06
## estatus_ocupacional3 -1.544515e-06
## freq_cons2 -1.788165e-06
## freq_cons3 -6.224027e-06
## freq_cons4 1.807193e-06
## freq_cons5 1.616906e-06
## freq_cons6 3.012098e-06
## edad_al_ing -1.044897e-06
## terap_disTerapeutic discharge:strata(event)event=2 -3.407278e-04
## terap_disTerapeutic discharge:strata(event)event=3 -3.740743e-04
## strata(event)event=2
## terap_disTerapeutic discharge 7.375441e-05
## strata(event)event=2 3.440834e-04
## strata(event)event=3 8.147571e-05
## sexF -1.129316e-05
## edad_inicio 1.350206e-06
## es_conyugalSeparated -9.018952e-06
## es_conyugalSingle -2.604995e-06
## es_conyugalWidower -1.096499e-07
## susCocaine -4.293879e-06
## susMarijuana 4.864145e-06
## susOther 6.075334e-06
## susCocaine paste -2.480529e-05
## escolaridadSecundaria o menor -2.107401e-06
## escolaridadPrimaria o menor 9.591917e-06
## compromiso_biopsicosocialModerate -6.663488e-06
## compromiso_biopsicosocialSevere -1.949241e-05
## tipo_programaEM -1.261088e-05
## estatus_ocupacional2 4.561618e-06
## estatus_ocupacional3 -4.083404e-06
## freq_cons2 2.442029e-05
## freq_cons3 2.139485e-05
## freq_cons4 3.326239e-05
## freq_cons5 3.148846e-05
## freq_cons6 2.769081e-05
## edad_al_ing -9.018094e-07
## terap_disTerapeutic discharge:strata(event)event=2 -3.472660e-04
## terap_disTerapeutic discharge:strata(event)event=3 -7.377079e-05
## strata(event)event=3
## terap_disTerapeutic discharge 7.199970e-05
## strata(event)event=2 8.147571e-05
## strata(event)event=3 1.075012e-03
## sexF -2.024646e-05
## edad_inicio 1.606184e-06
## es_conyugalSeparated 1.079038e-05
## es_conyugalSingle 9.604825e-06
## es_conyugalWidower -1.330631e-05
## susCocaine -2.584891e-05
## susMarijuana -1.454269e-05
## susOther 8.398594e-06
## susCocaine paste -6.362712e-05
## escolaridadSecundaria o menor 1.225700e-05
## escolaridadPrimaria o menor 2.446363e-05
## compromiso_biopsicosocialModerate -8.664503e-06
## compromiso_biopsicosocialSevere -2.303241e-05
## tipo_programaEM -2.228427e-05
## estatus_ocupacional2 1.687630e-05
## estatus_ocupacional3 -1.678057e-06
## freq_cons2 9.546931e-06
## freq_cons3 7.121912e-06
## freq_cons4 1.196649e-05
## freq_cons5 1.564368e-05
## freq_cons6 1.453746e-05
## edad_al_ing -1.366658e-06
## terap_disTerapeutic discharge:strata(event)event=2 -7.255939e-05
## terap_disTerapeutic discharge:strata(event)event=3 -1.063957e-03
## sexF edad_inicio
## terap_disTerapeutic discharge -5.796489e-06 -2.552394e-07
## strata(event)event=2 -1.129316e-05 1.350206e-06
## strata(event)event=3 -2.024646e-05 1.606184e-06
## sexF 3.532252e-04 -4.734144e-06
## edad_inicio -4.734144e-06 2.394533e-06
## es_conyugalSeparated -4.332863e-06 -9.337126e-07
## es_conyugalSingle 1.076380e-05 -1.701274e-07
## es_conyugalWidower -5.015161e-05 -2.830703e-06
## susCocaine -4.505574e-06 -6.694451e-07
## susMarijuana -5.585814e-06 2.354483e-07
## susOther -3.766662e-05 -9.144656e-06
## susCocaine paste 1.114165e-05 -7.188864e-07
## escolaridadSecundaria o menor -1.169656e-06 7.748672e-08
## escolaridadPrimaria o menor -1.290716e-05 1.873767e-06
## compromiso_biopsicosocialModerate -1.953358e-05 1.766047e-06
## compromiso_biopsicosocialSevere -2.081256e-05 3.517738e-06
## tipo_programaEM -2.512792e-04 1.226228e-06
## estatus_ocupacional2 1.822387e-05 4.498425e-07
## estatus_ocupacional3 -6.981719e-05 3.378678e-08
## freq_cons2 3.678967e-05 -3.171234e-06
## freq_cons3 4.716978e-05 -3.233735e-06
## freq_cons4 5.542485e-05 -2.476290e-06
## freq_cons5 5.886390e-05 -2.053123e-06
## freq_cons6 6.687521e-05 -1.844642e-06
## edad_al_ing 1.110651e-06 -3.663286e-07
## terap_disTerapeutic discharge:strata(event)event=2 9.865631e-06 -5.994830e-08
## terap_disTerapeutic discharge:strata(event)event=3 5.715624e-06 3.029689e-06
## es_conyugalSeparated
## terap_disTerapeutic discharge -2.686681e-07
## strata(event)event=2 -9.018952e-06
## strata(event)event=3 1.079038e-05
## sexF -4.332863e-06
## edad_inicio -9.337126e-07
## es_conyugalSeparated 5.609996e-04
## es_conyugalSingle 1.231097e-04
## es_conyugalWidower 1.602476e-04
## susCocaine 1.538515e-05
## susMarijuana 2.662514e-06
## susOther 1.205485e-05
## susCocaine paste 9.831500e-06
## escolaridadSecundaria o menor 1.667521e-05
## escolaridadPrimaria o menor 2.491881e-05
## compromiso_biopsicosocialModerate -1.481306e-05
## compromiso_biopsicosocialSevere -2.570749e-05
## tipo_programaEM -5.349395e-06
## estatus_ocupacional2 1.479370e-05
## estatus_ocupacional3 1.740036e-05
## freq_cons2 5.067149e-06
## freq_cons3 1.834802e-05
## freq_cons4 3.537239e-06
## freq_cons5 -4.073212e-07
## freq_cons6 -4.793166e-06
## edad_al_ing -2.088337e-06
## terap_disTerapeutic discharge:strata(event)event=2 5.209667e-06
## terap_disTerapeutic discharge:strata(event)event=3 -1.330760e-06
## es_conyugalSingle
## terap_disTerapeutic discharge 5.526680e-06
## strata(event)event=2 -2.604995e-06
## strata(event)event=3 9.604825e-06
## sexF 1.076380e-05
## edad_inicio -1.701274e-07
## es_conyugalSeparated 1.231097e-04
## es_conyugalSingle 2.395050e-04
## es_conyugalWidower 9.942128e-05
## susCocaine 1.593696e-05
## susMarijuana -5.554333e-06
## susOther -5.555056e-06
## susCocaine paste 3.308836e-06
## escolaridadSecundaria o menor 9.600637e-06
## escolaridadPrimaria o menor 1.449762e-05
## compromiso_biopsicosocialModerate -8.025913e-06
## compromiso_biopsicosocialSevere -1.699023e-05
## tipo_programaEM -1.044150e-05
## estatus_ocupacional2 2.846806e-05
## estatus_ocupacional3 1.019995e-05
## freq_cons2 3.975854e-06
## freq_cons3 -1.809527e-06
## freq_cons4 -1.028266e-05
## freq_cons5 -1.305105e-05
## freq_cons6 -1.665001e-05
## edad_al_ing 3.342353e-06
## terap_disTerapeutic discharge:strata(event)event=2 -9.531975e-06
## terap_disTerapeutic discharge:strata(event)event=3 -3.802103e-05
## es_conyugalWidower
## terap_disTerapeutic discharge 1.957091e-05
## strata(event)event=2 -1.096499e-07
## strata(event)event=3 -1.330631e-05
## sexF -5.015161e-05
## edad_inicio -2.830703e-06
## es_conyugalSeparated 1.602476e-04
## es_conyugalSingle 9.942128e-05
## es_conyugalWidower 5.122252e-03
## susCocaine 5.293836e-05
## susMarijuana -1.392547e-07
## susOther -3.256156e-05
## susCocaine paste 3.057950e-05
## escolaridadSecundaria o menor -1.581665e-06
## escolaridadPrimaria o menor -3.105053e-05
## compromiso_biopsicosocialModerate -1.101885e-05
## compromiso_biopsicosocialSevere -2.037648e-05
## tipo_programaEM 7.879564e-06
## estatus_ocupacional2 1.506103e-05
## estatus_ocupacional3 -3.669157e-05
## freq_cons2 3.470405e-05
## freq_cons3 3.130923e-05
## freq_cons4 2.164182e-05
## freq_cons5 3.018371e-05
## freq_cons6 1.993817e-05
## edad_al_ing -4.840631e-06
## terap_disTerapeutic discharge:strata(event)event=2 3.632496e-06
## terap_disTerapeutic discharge:strata(event)event=3 -1.139000e-05
## susCocaine susMarijuana
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## strata(event)event=2 -4.293879e-06 4.864145e-06
## strata(event)event=3 -2.584891e-05 -1.454269e-05
## sexF -4.505574e-06 -5.585814e-06
## edad_inicio -6.694451e-07 2.354483e-07
## es_conyugalSeparated 1.538515e-05 2.662514e-06
## es_conyugalSingle 1.593696e-05 -5.554333e-06
## es_conyugalWidower 5.293836e-05 -1.392547e-07
## susCocaine 4.691730e-04 2.362231e-04
## susMarijuana 2.362231e-04 1.125640e-03
## susOther 1.812554e-04 2.189664e-04
## susCocaine paste 2.274807e-04 2.441220e-04
## escolaridadSecundaria o menor 1.492222e-05 1.841027e-05
## escolaridadPrimaria o menor 3.888934e-05 3.512384e-05
## compromiso_biopsicosocialModerate -2.963879e-05 2.845348e-05
## compromiso_biopsicosocialSevere -4.345947e-05 4.583824e-05
## tipo_programaEM 8.261853e-07 1.782390e-05
## estatus_ocupacional2 1.826452e-06 -3.639886e-06
## estatus_ocupacional3 1.688243e-05 -1.641076e-05
## freq_cons2 -1.142213e-05 1.003427e-06
## freq_cons3 6.728045e-06 1.979903e-05
## freq_cons4 1.418272e-05 1.076251e-05
## freq_cons5 1.105244e-05 -8.334754e-06
## freq_cons6 8.460570e-06 -5.142320e-05
## edad_al_ing 4.287691e-06 5.859742e-06
## terap_disTerapeutic discharge:strata(event)event=2 -1.576344e-05 8.760167e-07
## terap_disTerapeutic discharge:strata(event)event=3 -8.657043e-06 2.101158e-05
## susOther
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## strata(event)event=3 8.398594e-06
## sexF -3.766662e-05
## edad_inicio -9.144656e-06
## es_conyugalSeparated 1.205485e-05
## es_conyugalSingle -5.555056e-06
## es_conyugalWidower -3.256156e-05
## susCocaine 1.812554e-04
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## susOther 3.243946e-03
## susCocaine paste 2.031915e-04
## escolaridadSecundaria o menor 2.893418e-05
## escolaridadPrimaria o menor 2.679723e-05
## compromiso_biopsicosocialModerate 1.422423e-06
## compromiso_biopsicosocialSevere 7.177105e-06
## tipo_programaEM 2.243487e-05
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## estatus_ocupacional3 -2.880673e-05
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## freq_cons3 7.617413e-05
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## freq_cons6 -1.865745e-05
## edad_al_ing 1.868575e-06
## terap_disTerapeutic discharge:strata(event)event=2 6.400383e-06
## terap_disTerapeutic discharge:strata(event)event=3 7.653579e-05
## susCocaine paste
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## sexF 1.114165e-05
## edad_inicio -7.188864e-07
## es_conyugalSeparated 9.831500e-06
## es_conyugalSingle 3.308836e-06
## es_conyugalWidower 3.057950e-05
## susCocaine 2.274807e-04
## susMarijuana 2.441220e-04
## susOther 2.031915e-04
## susCocaine paste 3.396103e-04
## escolaridadSecundaria o menor -1.417307e-05
## escolaridadPrimaria o menor -1.138716e-05
## compromiso_biopsicosocialModerate -4.064030e-05
## compromiso_biopsicosocialSevere -6.313829e-05
## tipo_programaEM -1.121960e-05
## estatus_ocupacional2 3.716837e-05
## estatus_ocupacional3 2.008864e-05
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## freq_cons3 3.096917e-05
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## freq_cons5 1.404637e-05
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## edad_al_ing 4.266151e-06
## terap_disTerapeutic discharge:strata(event)event=2 -3.978155e-06
## terap_disTerapeutic discharge:strata(event)event=3 1.400870e-06
## escolaridadSecundaria o menor
## terap_disTerapeutic discharge 1.961346e-05
## strata(event)event=2 -2.107401e-06
## strata(event)event=3 1.225700e-05
## sexF -1.169656e-06
## edad_inicio 7.748672e-08
## es_conyugalSeparated 1.667521e-05
## es_conyugalSingle 9.600637e-06
## es_conyugalWidower -1.581665e-06
## susCocaine 1.492222e-05
## susMarijuana 1.841027e-05
## susOther 2.893418e-05
## susCocaine paste -1.417307e-05
## escolaridadSecundaria o menor 3.243900e-04
## escolaridadPrimaria o menor 2.542206e-04
## compromiso_biopsicosocialModerate -6.223311e-06
## compromiso_biopsicosocialSevere -1.763639e-05
## tipo_programaEM -2.496129e-07
## estatus_ocupacional2 -5.024324e-06
## estatus_ocupacional3 -3.211986e-06
## freq_cons2 -4.917067e-06
## freq_cons3 8.773301e-06
## freq_cons4 2.587354e-06
## freq_cons5 8.799099e-06
## freq_cons6 2.386128e-06
## edad_al_ing 1.910244e-07
## terap_disTerapeutic discharge:strata(event)event=2 6.117545e-06
## terap_disTerapeutic discharge:strata(event)event=3 -5.620667e-05
## escolaridadPrimaria o menor
## terap_disTerapeutic discharge 3.106026e-05
## strata(event)event=2 9.591917e-06
## strata(event)event=3 2.446363e-05
## sexF -1.290716e-05
## edad_inicio 1.873767e-06
## es_conyugalSeparated 2.491881e-05
## es_conyugalSingle 1.449762e-05
## es_conyugalWidower -3.105053e-05
## susCocaine 3.888934e-05
## susMarijuana 3.512384e-05
## susOther 2.679723e-05
## susCocaine paste -1.138716e-05
## escolaridadSecundaria o menor 2.542206e-04
## escolaridadPrimaria o menor 4.423056e-04
## compromiso_biopsicosocialModerate -6.228333e-06
## compromiso_biopsicosocialSevere -2.828270e-05
## tipo_programaEM 2.584463e-06
## estatus_ocupacional2 -7.118919e-06
## estatus_ocupacional3 -1.829712e-05
## freq_cons2 1.734409e-06
## freq_cons3 1.437843e-05
## freq_cons4 1.296847e-05
## freq_cons5 2.140475e-05
## freq_cons6 1.035923e-05
## edad_al_ing -8.249486e-07
## terap_disTerapeutic discharge:strata(event)event=2 -1.058836e-06
## terap_disTerapeutic discharge:strata(event)event=3 -6.099056e-05
## compromiso_biopsicosocialModerate
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## strata(event)event=3 -8.664503e-06
## sexF -1.953358e-05
## edad_inicio 1.766047e-06
## es_conyugalSeparated -1.481306e-05
## es_conyugalSingle -8.025913e-06
## es_conyugalWidower -1.101885e-05
## susCocaine -2.963879e-05
## susMarijuana 2.845348e-05
## susOther 1.422423e-06
## susCocaine paste -4.064030e-05
## escolaridadSecundaria o menor -6.223311e-06
## escolaridadPrimaria o menor -6.228333e-06
## compromiso_biopsicosocialModerate 7.816682e-04
## compromiso_biopsicosocialSevere 7.309785e-04
## tipo_programaEM 1.033208e-07
## estatus_ocupacional2 1.704786e-05
## estatus_ocupacional3 7.506129e-07
## freq_cons2 5.713612e-05
## freq_cons3 2.616427e-05
## freq_cons4 -5.266953e-05
## freq_cons5 -7.405811e-05
## freq_cons6 -7.010363e-05
## edad_al_ing -2.157887e-07
## terap_disTerapeutic discharge:strata(event)event=2 -7.001194e-06
## terap_disTerapeutic discharge:strata(event)event=3 -1.688251e-05
## compromiso_biopsicosocialSevere
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## sexF -2.081256e-05
## edad_inicio 3.517738e-06
## es_conyugalSeparated -2.570749e-05
## es_conyugalSingle -1.699023e-05
## es_conyugalWidower -2.037648e-05
## susCocaine -4.345947e-05
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## susOther 7.177105e-06
## susCocaine paste -6.313829e-05
## escolaridadSecundaria o menor -1.763639e-05
## escolaridadPrimaria o menor -2.828270e-05
## compromiso_biopsicosocialModerate 7.309785e-04
## compromiso_biopsicosocialSevere 8.994069e-04
## tipo_programaEM -3.390697e-05
## estatus_ocupacional2 5.258343e-05
## estatus_ocupacional3 7.894535e-06
## freq_cons2 6.317911e-05
## freq_cons3 3.616783e-05
## freq_cons4 -5.614923e-05
## freq_cons5 -1.021731e-04
## freq_cons6 -1.253483e-04
## edad_al_ing -4.250625e-07
## terap_disTerapeutic discharge:strata(event)event=2 1.923986e-06
## terap_disTerapeutic discharge:strata(event)event=3 -6.002472e-06
## tipo_programaEM
## terap_disTerapeutic discharge -9.381193e-06
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## sexF -2.512792e-04
## edad_inicio 1.226228e-06
## es_conyugalSeparated -5.349395e-06
## es_conyugalSingle -1.044150e-05
## es_conyugalWidower 7.879564e-06
## susCocaine 8.261853e-07
## susMarijuana 1.782390e-05
## susOther 2.243487e-05
## susCocaine paste -1.121960e-05
## escolaridadSecundaria o menor -2.496129e-07
## escolaridadPrimaria o menor 2.584463e-06
## compromiso_biopsicosocialModerate 1.033208e-07
## compromiso_biopsicosocialSevere -3.390697e-05
## tipo_programaEM 5.413801e-04
## estatus_ocupacional2 1.725276e-06
## estatus_ocupacional3 -1.006559e-05
## freq_cons2 1.022208e-05
## freq_cons3 4.200987e-06
## freq_cons4 -5.774309e-06
## freq_cons5 -1.179317e-05
## freq_cons6 -1.921359e-05
## edad_al_ing 3.170562e-07
## terap_disTerapeutic discharge:strata(event)event=2 -4.955786e-07
## terap_disTerapeutic discharge:strata(event)event=3 9.161350e-08
## estatus_ocupacional2
## terap_disTerapeutic discharge -2.112481e-06
## strata(event)event=2 4.561618e-06
## strata(event)event=3 1.687630e-05
## sexF 1.822387e-05
## edad_inicio 4.498425e-07
## es_conyugalSeparated 1.479370e-05
## es_conyugalSingle 2.846806e-05
## es_conyugalWidower 1.506103e-05
## susCocaine 1.826452e-06
## susMarijuana -3.639886e-06
## susOther 2.575361e-05
## susCocaine paste 3.716837e-05
## escolaridadSecundaria o menor -5.024324e-06
## escolaridadPrimaria o menor -7.118919e-06
## compromiso_biopsicosocialModerate 1.704786e-05
## compromiso_biopsicosocialSevere 5.258343e-05
## tipo_programaEM 1.725276e-06
## estatus_ocupacional2 2.518464e-04
## estatus_ocupacional3 1.081779e-04
## freq_cons2 -2.541008e-06
## freq_cons3 -3.313477e-06
## freq_cons4 -1.748017e-06
## freq_cons5 1.961694e-05
## freq_cons6 3.407899e-05
## edad_al_ing -6.748552e-07
## terap_disTerapeutic discharge:strata(event)event=2 6.344990e-06
## terap_disTerapeutic discharge:strata(event)event=3 -1.428089e-05
## estatus_ocupacional3
## terap_disTerapeutic discharge -1.544515e-06
## strata(event)event=2 -4.083404e-06
## strata(event)event=3 -1.678057e-06
## sexF -6.981719e-05
## edad_inicio 3.378678e-08
## es_conyugalSeparated 1.740036e-05
## es_conyugalSingle 1.019995e-05
## es_conyugalWidower -3.669157e-05
## susCocaine 1.688243e-05
## susMarijuana -1.641076e-05
## susOther -2.880673e-05
## susCocaine paste 2.008864e-05
## escolaridadSecundaria o menor -3.211986e-06
## escolaridadPrimaria o menor -1.829712e-05
## compromiso_biopsicosocialModerate 7.506129e-07
## compromiso_biopsicosocialSevere 7.894535e-06
## tipo_programaEM -1.006559e-05
## estatus_ocupacional2 1.081779e-04
## estatus_ocupacional3 3.560138e-04
## freq_cons2 -8.888724e-07
## freq_cons3 1.614389e-06
## freq_cons4 3.544295e-07
## freq_cons5 7.431241e-06
## freq_cons6 5.036172e-06
## edad_al_ing -4.333612e-07
## terap_disTerapeutic discharge:strata(event)event=2 1.322403e-06
## terap_disTerapeutic discharge:strata(event)event=3 -2.331442e-05
## freq_cons2 freq_cons3
## terap_disTerapeutic discharge -1.788165e-06 -6.224027e-06
## strata(event)event=2 2.442029e-05 2.139485e-05
## strata(event)event=3 9.546931e-06 7.121912e-06
## sexF 3.678967e-05 4.716978e-05
## edad_inicio -3.171234e-06 -3.233735e-06
## es_conyugalSeparated 5.067149e-06 1.834802e-05
## es_conyugalSingle 3.975854e-06 -1.809527e-06
## es_conyugalWidower 3.470405e-05 3.130923e-05
## susCocaine -1.142213e-05 6.728045e-06
## susMarijuana 1.003427e-06 1.979903e-05
## susOther 6.194944e-05 7.617413e-05
## susCocaine paste 1.359971e-05 3.096917e-05
## escolaridadSecundaria o menor -4.917067e-06 8.773301e-06
## escolaridadPrimaria o menor 1.734409e-06 1.437843e-05
## compromiso_biopsicosocialModerate 5.713612e-05 2.616427e-05
## compromiso_biopsicosocialSevere 6.317911e-05 3.616783e-05
## tipo_programaEM 1.022208e-05 4.200987e-06
## estatus_ocupacional2 -2.541008e-06 -3.313477e-06
## estatus_ocupacional3 -8.888724e-07 1.614389e-06
## freq_cons2 4.490347e-03 3.122758e-03
## freq_cons3 3.122758e-03 3.857686e-03
## freq_cons4 3.119018e-03 3.117489e-03
## freq_cons5 3.103547e-03 3.108315e-03
## freq_cons6 3.100030e-03 3.098803e-03
## edad_al_ing 2.958296e-07 3.729365e-07
## terap_disTerapeutic discharge:strata(event)event=2 3.347491e-05 5.390366e-05
## terap_disTerapeutic discharge:strata(event)event=3 8.495628e-05 3.392524e-05
## freq_cons4 freq_cons5
## terap_disTerapeutic discharge 1.807193e-06 1.616906e-06
## strata(event)event=2 3.326239e-05 3.148846e-05
## strata(event)event=3 1.196649e-05 1.564368e-05
## sexF 5.542485e-05 5.886390e-05
## edad_inicio -2.476290e-06 -2.053123e-06
## es_conyugalSeparated 3.537239e-06 -4.073212e-07
## es_conyugalSingle -1.028266e-05 -1.305105e-05
## es_conyugalWidower 2.164182e-05 3.018371e-05
## susCocaine 1.418272e-05 1.105244e-05
## susMarijuana 1.076251e-05 -8.334754e-06
## susOther 6.142219e-05 5.016188e-05
## susCocaine paste 3.449532e-05 1.404637e-05
## escolaridadSecundaria o menor 2.587354e-06 8.799099e-06
## escolaridadPrimaria o menor 1.296847e-05 2.140475e-05
## compromiso_biopsicosocialModerate -5.266953e-05 -7.405811e-05
## compromiso_biopsicosocialSevere -5.614923e-05 -1.021731e-04
## tipo_programaEM -5.774309e-06 -1.179317e-05
## estatus_ocupacional2 -1.748017e-06 1.961694e-05
## estatus_ocupacional3 3.544295e-07 7.431241e-06
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## freq_cons3 3.117489e-03 3.108315e-03
## freq_cons4 3.303072e-03 3.133413e-03
## freq_cons5 3.133413e-03 3.408268e-03
## freq_cons6 3.126941e-03 3.147626e-03
## edad_al_ing 5.064581e-07 2.783324e-07
## terap_disTerapeutic discharge:strata(event)event=2 4.388505e-05 4.783774e-05
## terap_disTerapeutic discharge:strata(event)event=3 5.747926e-05 5.907596e-05
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## terap_disTerapeutic discharge 3.012098e-06 -1.044897e-06
## strata(event)event=2 2.769081e-05 -9.018094e-07
## strata(event)event=3 1.453746e-05 -1.366658e-06
## sexF 6.687521e-05 1.110651e-06
## edad_inicio -1.844642e-06 -3.663286e-07
## es_conyugalSeparated -4.793166e-06 -2.088337e-06
## es_conyugalSingle -1.665001e-05 3.342353e-06
## es_conyugalWidower 1.993817e-05 -4.840631e-06
## susCocaine 8.460570e-06 4.287691e-06
## susMarijuana -5.142320e-05 5.859742e-06
## susOther -1.865745e-05 1.868575e-06
## susCocaine paste -9.435368e-06 4.266151e-06
## escolaridadSecundaria o menor 2.386128e-06 1.910244e-07
## escolaridadPrimaria o menor 1.035923e-05 -8.249486e-07
## compromiso_biopsicosocialModerate -7.010363e-05 -2.157887e-07
## compromiso_biopsicosocialSevere -1.253483e-04 -4.250625e-07
## tipo_programaEM -1.921359e-05 3.170562e-07
## estatus_ocupacional2 3.407899e-05 -6.748552e-07
## estatus_ocupacional3 5.036172e-06 -4.333612e-07
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## freq_cons4 3.126941e-03 5.064581e-07
## freq_cons5 3.147626e-03 2.783324e-07
## freq_cons6 3.249064e-03 -3.938200e-07
## edad_al_ing -3.938200e-07 6.417693e-07
## terap_disTerapeutic discharge:strata(event)event=2 4.599921e-05 3.146991e-07
## terap_disTerapeutic discharge:strata(event)event=3 4.096532e-05 4.647090e-08
## terap_disTerapeutic discharge:strata(event)event=2
## terap_disTerapeutic discharge -3.407278e-04
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## sexF 9.865631e-06
## edad_inicio -5.994830e-08
## es_conyugalSeparated 5.209667e-06
## es_conyugalSingle -9.531975e-06
## es_conyugalWidower 3.632496e-06
## susCocaine -1.576344e-05
## susMarijuana 8.760167e-07
## susOther 6.400383e-06
## susCocaine paste -3.978155e-06
## escolaridadSecundaria o menor 6.117545e-06
## escolaridadPrimaria o menor -1.058836e-06
## compromiso_biopsicosocialModerate -7.001194e-06
## compromiso_biopsicosocialSevere 1.923986e-06
## tipo_programaEM -4.955786e-07
## estatus_ocupacional2 6.344990e-06
## estatus_ocupacional3 1.322403e-06
## freq_cons2 3.347491e-05
## freq_cons3 5.390366e-05
## freq_cons4 4.388505e-05
## freq_cons5 4.783774e-05
## freq_cons6 4.599921e-05
## edad_al_ing 3.146991e-07
## terap_disTerapeutic discharge:strata(event)event=2 1.690029e-03
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## terap_disTerapeutic discharge:strata(event)event=3
## terap_disTerapeutic discharge -3.740743e-04
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## sexF 5.715624e-06
## edad_inicio 3.029689e-06
## es_conyugalSeparated -1.330760e-06
## es_conyugalSingle -3.802103e-05
## es_conyugalWidower -1.139000e-05
## susCocaine -8.657043e-06
## susMarijuana 2.101158e-05
## susOther 7.653579e-05
## susCocaine paste 1.400870e-06
## escolaridadSecundaria o menor -5.620667e-05
## escolaridadPrimaria o menor -6.099056e-05
## compromiso_biopsicosocialModerate -1.688251e-05
## compromiso_biopsicosocialSevere -6.002472e-06
## tipo_programaEM 9.161350e-08
## estatus_ocupacional2 -1.428089e-05
## estatus_ocupacional3 -2.331442e-05
## freq_cons2 8.495628e-05
## freq_cons3 3.392524e-05
## freq_cons4 5.747926e-05
## freq_cons5 5.907596e-05
## freq_cons6 4.096532e-05
## edad_al_ing 4.647090e-08
## terap_disTerapeutic discharge:strata(event)event=2 3.546245e-04
## terap_disTerapeutic discharge:strata(event)event=3 5.224665e-03
##
## Generalized concordance probability: Estimates may be biased!
## concordance prob. lower 0.95
## terap_disTerapeutic discharge 0.4431 0.4341
## strata(event)event=2 0.6195 0.6109
## strata(event)event=3 0.6788 0.6647
## sexF 0.5472 0.5380
## edad_inicio 0.4975 0.4967
## es_conyugalSeparated 0.5002 0.4886
## es_conyugalSingle 0.4905 0.4830
## es_conyugalWidower 0.4741 0.4393
## susCocaine 0.5420 0.5314
## susMarijuana 0.4682 0.4518
## susOther 0.4956 0.4678
## susCocaine paste 0.5812 0.5723
## escolaridadSecundaria o menor 0.4783 0.4695
## escolaridadPrimaria o menor 0.4368 0.4267
## compromiso_biopsicosocialModerate 0.5170 0.5033
## compromiso_biopsicosocialSevere 0.5672 0.5527
## tipo_programaEM 0.5593 0.5480
## estatus_ocupacional2 0.4761 0.4684
## estatus_ocupacional3 0.4895 0.4803
## freq_cons2 0.5127 0.4799
## freq_cons3 0.5200 0.4896
## freq_cons4 0.5275 0.4994
## freq_cons5 0.5297 0.5011
## freq_cons6 0.5328 0.5049
## edad_al_ing 0.4979 0.4975
## terap_disTerapeutic discharge:strata(event)event=2 0.5018 0.4817
## terap_disTerapeutic discharge:strata(event)event=3 0.5097 0.4743
## upper 0.95
## terap_disTerapeutic discharge 0.4522
## strata(event)event=2 0.6280
## strata(event)event=3 0.6927
## sexF 0.5563
## edad_inicio 0.4982
## es_conyugalSeparated 0.5118
## es_conyugalSingle 0.4981
## es_conyugalWidower 0.5092
## susCocaine 0.5525
## susMarijuana 0.4846
## susOther 0.5235
## susCocaine paste 0.5899
## escolaridadSecundaria o menor 0.4871
## escolaridadPrimaria o menor 0.4470
## compromiso_biopsicosocialModerate 0.5307
## compromiso_biopsicosocialSevere 0.5815
## tipo_programaEM 0.5705
## estatus_ocupacional2 0.4839
## estatus_ocupacional3 0.4987
## freq_cons2 0.5455
## freq_cons3 0.5503
## freq_cons4 0.5555
## freq_cons5 0.5581
## freq_cons6 0.5604
## edad_al_ing 0.4983
## terap_disTerapeutic discharge:strata(event)event=2 0.5220
## terap_disTerapeutic discharge:strata(event)event=3 0.5450# res_gt_3 <- cbind.data.frame(Avg_HR=round(exp(pwp_gt_imp3$coeff),2),
# Lo_ci95=round(exp(confint(pwp_gt_imp3))[,1],2),
# Up_ci95=round(exp(confint(pwp_gt_imp3))[,2],2),
# p=round(summary(pwp_gt_imp3)$prob,4))%>%
# data.table::data.table(keep.rownames=T)
#
# conc_gt_3 <- cbind.data.frame(conc_prob=concord(pwp_gt_imp3)[,1],
# lo_ci95=concord(pwp_gt_imp3)[,2],
# up_ci95=concord(pwp_gt_imp3)[,3],
# conc_p=summary(pwp_gt_imp3, print = FALSE)$prob)%>%
# data.table::data.table(keep.rownames=T)
res_gt_3_cl <- cbind.data.frame(Avg_HR=round(exp(pwp_gt_imp3_cl$coeff),2),
Lo_ci95=round(exp(confint(pwp_gt_imp3_cl))[,1],2),
Up_ci95=round(exp(confint(pwp_gt_imp3_cl))[,2],2),
p=round(summary(pwp_gt_imp3_cl)$prob,4))%>%
data.table::data.table(keep.rownames=T)## coxphw(formula = Surv(tstart2, tstop2, status == 1) ~ terap_dis *
## strata(event) + sex + edad_inicio + es_conyugal + sus + escolaridad +
## compromiso_biopsicosocial + tipo_programa + estatus_ocupacional +
## freq_cons + edad_al_ing + strata(event), data = rfimp2, template = "AHR",
## robust = T, clusterid = rfimp2$id)
##
## Model fitted by weighted estimation (AHR template)
##
## coef se(coef)
## terap_disTerapeutic discharge -0.132878831 0.036074273
## strata(event)event=2 0.488014349 0.019830016
## strata(event)event=3 0.744628769 0.033607759
## sexF 0.231823036 0.044112547
## edad_inicio -0.015684453 0.002392896
## es_conyugalSeparated -0.016370696 0.027286442
## es_conyugalSingle -0.018433062 0.022244926
## es_conyugalWidower -0.106891796 0.076593687
## susCocaine 0.179007443 0.024804258
## susMarijuana -0.121589723 0.045799981
## susOther -0.024592675 0.070081448
## susCocaine paste 0.348116678 0.025861209
## escolaridadSecundaria o menor -0.063565354 0.023146862
## escolaridadPrimaria o menor -0.241788244 0.024519462
## compromiso_biopsicosocialModerate 0.047512558 0.053185874
## compromiso_biopsicosocialSevere 0.207896855 0.055133609
## tipo_programaEM 0.203903168 0.040402289
## estatus_ocupacional2 -0.084241800 0.025431126
## estatus_ocupacional3 -0.055911329 0.029449742
## freq_cons2 0.026813308 0.071464785
## freq_cons3 0.150825402 0.072811905
## freq_cons4 0.149409108 0.065665011
## freq_cons5 0.128422875 0.062466044
## freq_cons6 0.151901938 0.061860128
## edad_al_ing -0.007459906 0.001119312
## terap_disTerapeutic discharge:strata(event)event=2 -0.030545463 0.051709538
## terap_disTerapeutic discharge:strata(event)event=3 -0.035975233 0.078242701
## exp(coef) lower 0.95
## terap_disTerapeutic discharge 0.8755712 0.8158024
## strata(event)event=2 1.6290782 1.5669769
## strata(event)event=3 2.1056596 1.9714292
## sexF 1.2608966 1.1564605
## edad_inicio 0.9844379 0.9798317
## es_conyugalSeparated 0.9837626 0.9325326
## es_conyugalSingle 0.9817358 0.9398525
## es_conyugalWidower 0.8986229 0.7733584
## susCocaine 1.1960296 1.1392749
## susMarijuana 0.8855116 0.8094858
## susOther 0.9757073 0.8504839
## susCocaine paste 1.4163975 1.3463936
## escolaridadSecundaria o menor 0.9384128 0.8967911
## escolaridadPrimaria o menor 0.7852224 0.7483792
## compromiso_biopsicosocialModerate 1.0486594 0.9448493
## compromiso_biopsicosocialSevere 1.2310862 1.1049908
## tipo_programaEM 1.2261794 1.1328268
## estatus_ocupacional2 0.9192090 0.8745149
## estatus_ocupacional3 0.9456230 0.8925866
## freq_cons2 1.0271760 0.8929228
## freq_cons3 1.1627936 1.0081497
## freq_cons4 1.1611479 1.0209240
## freq_cons5 1.1370337 1.0060097
## freq_cons6 1.1640461 1.0311331
## edad_al_ing 0.9925679 0.9903927
## terap_disTerapeutic discharge:strata(event)event=2 0.9699163 0.8764336
## terap_disTerapeutic discharge:strata(event)event=3 0.9646642 0.8275149
## upper 0.95 z
## terap_disTerapeutic discharge 0.9397188 -3.6834791
## strata(event)event=2 1.6936407 24.6098819
## strata(event)event=3 2.2490294 22.1564541
## sexF 1.3747639 5.2552630
## edad_inicio 0.9890658 -6.5545894
## es_conyugalSeparated 1.0378069 -0.5999571
## es_conyugalSingle 1.0254855 -0.8286412
## es_conyugalWidower 1.0441771 -1.3955693
## susCocaine 1.2556117 7.2168030
## susMarijuana 0.9686776 -2.6547985
## susOther 1.1193682 -0.3509156
## susCocaine paste 1.4900411 13.4609593
## escolaridadSecundaria o menor 0.9819663 -2.7461758
## escolaridadPrimaria o menor 0.8238795 -9.8610747
## compromiso_biopsicosocialModerate 1.1638750 0.8933304
## compromiso_biopsicosocialSevere 1.3715709 3.7707826
## tipo_programaEM 1.3272249 5.0468222
## estatus_ocupacional2 0.9661872 -3.3125470
## estatus_ocupacional3 1.0018107 -1.8985338
## freq_cons2 1.1816145 0.3751961
## freq_cons3 1.3411589 2.0714387
## freq_cons4 1.3206317 2.2753230
## freq_cons5 1.2851225 2.0558830
## freq_cons6 1.3140915 2.4555710
## edad_al_ing 0.9947477 -6.6647218
## terap_disTerapeutic discharge:strata(event)event=2 1.0733701 -0.5907124
## terap_disTerapeutic discharge:strata(event)event=3 1.1245440 -0.4597903
## p
## terap_disTerapeutic discharge 2.300721e-04
## strata(event)event=2 0.000000e+00
## strata(event)event=3 0.000000e+00
## sexF 1.478131e-07
## edad_inicio 5.579515e-11
## es_conyugalSeparated 5.485348e-01
## es_conyugalSingle 4.073075e-01
## es_conyugalWidower 1.628442e-01
## susCocaine 5.322409e-13
## susMarijuana 7.935579e-03
## susOther 7.256517e-01
## susCocaine paste 0.000000e+00
## escolaridadSecundaria o menor 6.029444e-03
## escolaridadPrimaria o menor 0.000000e+00
## compromiso_biopsicosocialModerate 3.716803e-01
## compromiso_biopsicosocialSevere 1.627364e-04
## tipo_programaEM 4.492190e-07
## estatus_ocupacional2 9.245057e-04
## estatus_ocupacional3 5.762580e-02
## freq_cons2 7.075146e-01
## freq_cons3 3.831781e-02
## freq_cons4 2.288656e-02
## freq_cons5 3.979380e-02
## freq_cons6 1.406610e-02
## edad_al_ing 2.651668e-11
## terap_disTerapeutic discharge:strata(event)event=2 5.547132e-01
## terap_disTerapeutic discharge:strata(event)event=3 6.456668e-01
##
## Wald Chi-square = 4208.288 on 27 df p = 0 n = 107665
##
## Covariance-Matrix:
## terap_disTerapeutic discharge
## terap_disTerapeutic discharge 1.301353e-03
## strata(event)event=2 2.146151e-04
## strata(event)event=3 1.821069e-04
## sexF 9.411185e-04
## edad_inicio -3.897668e-05
## es_conyugalSeparated 7.805985e-05
## es_conyugalSingle 3.752451e-04
## es_conyugalWidower 1.688637e-04
## susCocaine 1.275061e-05
## susMarijuana -1.814291e-04
## susOther -3.938972e-04
## susCocaine paste 2.633661e-04
## escolaridadSecundaria o menor 2.779500e-04
## escolaridadPrimaria o menor 1.411078e-04
## compromiso_biopsicosocialModerate 7.697965e-04
## compromiso_biopsicosocialSevere 4.805736e-04
## tipo_programaEM -7.425342e-04
## estatus_ocupacional2 -3.657213e-04
## estatus_ocupacional3 -4.941136e-04
## freq_cons2 2.669706e-05
## freq_cons3 6.548132e-05
## freq_cons4 5.702189e-04
## freq_cons5 -5.890255e-05
## freq_cons6 -3.263008e-05
## edad_al_ing 2.967897e-06
## terap_disTerapeutic discharge:strata(event)event=2 -1.205693e-03
## terap_disTerapeutic discharge:strata(event)event=3 -1.249682e-03
## strata(event)event=2
## terap_disTerapeutic discharge 2.146151e-04
## strata(event)event=2 3.932295e-04
## strata(event)event=3 1.105980e-04
## sexF 8.138849e-05
## edad_inicio -2.420679e-06
## es_conyugalSeparated 5.428832e-06
## es_conyugalSingle 4.029216e-05
## es_conyugalWidower 4.273711e-05
## susCocaine -5.206198e-06
## susMarijuana 2.425032e-05
## susOther -3.415253e-05
## susCocaine paste -1.852791e-05
## escolaridadSecundaria o menor 2.946047e-05
## escolaridadPrimaria o menor 2.774271e-05
## compromiso_biopsicosocialModerate 1.127785e-04
## compromiso_biopsicosocialSevere 6.775931e-05
## tipo_programaEM -8.521223e-05
## estatus_ocupacional2 -3.149736e-05
## estatus_ocupacional3 -5.945371e-05
## freq_cons2 3.746010e-05
## freq_cons3 7.280202e-05
## freq_cons4 1.055268e-04
## freq_cons5 3.308808e-05
## freq_cons6 2.561342e-05
## edad_al_ing -1.479737e-06
## terap_disTerapeutic discharge:strata(event)event=2 -4.799037e-04
## terap_disTerapeutic discharge:strata(event)event=3 -2.040180e-04
## strata(event)event=3
## terap_disTerapeutic discharge 1.821069e-04
## strata(event)event=2 1.105980e-04
## strata(event)event=3 1.129481e-03
## sexF 2.134945e-05
## edad_inicio -1.031478e-07
## es_conyugalSeparated 2.174464e-05
## es_conyugalSingle 3.366565e-05
## es_conyugalWidower 1.453022e-05
## susCocaine -2.278998e-05
## susMarijuana 3.234264e-05
## susOther -4.697453e-06
## susCocaine paste -7.197267e-05
## escolaridadSecundaria o menor 3.329137e-05
## escolaridadPrimaria o menor 4.099458e-05
## compromiso_biopsicosocialModerate 8.692001e-05
## compromiso_biopsicosocialSevere 5.696462e-05
## tipo_programaEM -5.676817e-05
## estatus_ocupacional2 5.593456e-06
## estatus_ocupacional3 -3.032579e-05
## freq_cons2 2.522699e-05
## freq_cons3 7.489597e-05
## freq_cons4 5.985171e-05
## freq_cons5 2.101616e-05
## freq_cons6 1.463989e-05
## edad_al_ing -2.520571e-06
## terap_disTerapeutic discharge:strata(event)event=2 -1.652073e-04
## terap_disTerapeutic discharge:strata(event)event=3 -1.191342e-03
## sexF edad_inicio
## terap_disTerapeutic discharge 9.411185e-04 -3.897668e-05
## strata(event)event=2 8.138849e-05 -2.420679e-06
## strata(event)event=3 2.134945e-05 -1.031478e-07
## sexF 1.945917e-03 -6.365609e-05
## edad_inicio -6.365609e-05 5.725953e-06
## es_conyugalSeparated -4.997461e-06 -1.328742e-06
## es_conyugalSingle 4.954638e-04 -1.895949e-05
## es_conyugalWidower 4.342675e-05 -7.956951e-06
## susCocaine -5.665502e-05 -7.751782e-07
## susMarijuana -4.278857e-04 1.507532e-05
## susOther -6.702606e-04 1.956684e-05
## susCocaine paste 4.895966e-04 -2.144882e-05
## escolaridadSecundaria o menor 4.099800e-04 -1.601728e-05
## escolaridadPrimaria o menor 1.727695e-05 -5.217762e-07
## compromiso_biopsicosocialModerate 4.729041e-04 -1.583868e-05
## compromiso_biopsicosocialSevere -2.397605e-05 8.248387e-06
## tipo_programaEM -1.497100e-03 4.681092e-05
## estatus_ocupacional2 -6.291510e-04 2.508371e-05
## estatus_ocupacional3 -8.841367e-04 2.836171e-05
## freq_cons2 5.699637e-06 -2.999061e-06
## freq_cons3 2.344919e-05 -7.253675e-06
## freq_cons4 9.685129e-04 -3.863589e-05
## freq_cons5 5.733385e-05 -2.941733e-06
## freq_cons6 1.304731e-04 -6.881435e-06
## edad_al_ing 1.633980e-05 -1.064923e-06
## terap_disTerapeutic discharge:strata(event)event=2 -8.199747e-04 3.242230e-05
## terap_disTerapeutic discharge:strata(event)event=3 -8.604603e-04 3.840462e-05
## es_conyugalSeparated
## terap_disTerapeutic discharge 7.805985e-05
## strata(event)event=2 5.428832e-06
## strata(event)event=3 2.174464e-05
## sexF -4.997461e-06
## edad_inicio -1.328742e-06
## es_conyugalSeparated 7.445499e-04
## es_conyugalSingle 1.916109e-04
## es_conyugalWidower 2.977471e-04
## susCocaine -2.208719e-05
## susMarijuana 9.799655e-05
## susOther 4.425482e-05
## susCocaine paste -6.504150e-05
## escolaridadSecundaria o menor -1.835553e-05
## escolaridadPrimaria o menor 3.606385e-05
## compromiso_biopsicosocialModerate 2.936017e-04
## compromiso_biopsicosocialSevere 3.069970e-04
## tipo_programaEM -2.229892e-05
## estatus_ocupacional2 -2.394750e-05
## estatus_ocupacional3 1.355837e-05
## freq_cons2 4.336851e-05
## freq_cons3 9.306991e-05
## freq_cons4 -5.238441e-05
## freq_cons5 -6.488761e-05
## freq_cons6 -1.203665e-04
## edad_al_ing -7.580829e-06
## terap_disTerapeutic discharge:strata(event)event=2 -7.080377e-05
## terap_disTerapeutic discharge:strata(event)event=3 -5.981260e-05
## es_conyugalSingle
## terap_disTerapeutic discharge 3.752451e-04
## strata(event)event=2 4.029216e-05
## strata(event)event=3 3.366565e-05
## sexF 4.954638e-04
## edad_inicio -1.895949e-05
## es_conyugalSeparated 1.916109e-04
## es_conyugalSingle 4.948367e-04
## es_conyugalWidower 1.894481e-04
## susCocaine -1.370316e-05
## susMarijuana -4.139490e-05
## susOther -2.049115e-04
## susCocaine paste 1.503301e-04
## escolaridadSecundaria o menor 1.333297e-04
## escolaridadPrimaria o menor 8.165930e-05
## compromiso_biopsicosocialModerate 2.537843e-04
## compromiso_biopsicosocialSevere 1.192701e-04
## tipo_programaEM -4.098608e-04
## estatus_ocupacional2 -1.476197e-04
## estatus_ocupacional3 -2.429409e-04
## freq_cons2 -1.673272e-06
## freq_cons3 1.051006e-04
## freq_cons4 2.462641e-04
## freq_cons5 -5.129743e-05
## freq_cons6 -3.708902e-05
## edad_al_ing 7.144162e-06
## terap_disTerapeutic discharge:strata(event)event=2 -3.436757e-04
## terap_disTerapeutic discharge:strata(event)event=3 -3.725628e-04
## es_conyugalWidower
## terap_disTerapeutic discharge 1.688637e-04
## strata(event)event=2 4.273711e-05
## strata(event)event=3 1.453022e-05
## sexF 4.342675e-05
## edad_inicio -7.956951e-06
## es_conyugalSeparated 2.977471e-04
## es_conyugalSingle 1.894481e-04
## es_conyugalWidower 5.866593e-03
## susCocaine -7.855462e-07
## susMarijuana 1.224629e-04
## susOther -7.158916e-05
## susCocaine paste -3.509456e-05
## escolaridadSecundaria o menor -2.289360e-05
## escolaridadPrimaria o menor -4.305278e-05
## compromiso_biopsicosocialModerate 3.759992e-04
## compromiso_biopsicosocialSevere 3.567035e-04
## tipo_programaEM -9.580010e-05
## estatus_ocupacional2 -6.641073e-05
## estatus_ocupacional3 -9.363211e-05
## freq_cons2 6.330174e-05
## freq_cons3 1.339900e-04
## freq_cons4 2.805734e-05
## freq_cons5 -3.892097e-05
## freq_cons6 -1.114433e-04
## edad_al_ing -1.125948e-05
## terap_disTerapeutic discharge:strata(event)event=2 -1.508448e-04
## terap_disTerapeutic discharge:strata(event)event=3 -1.335706e-04
## susCocaine susMarijuana
## terap_disTerapeutic discharge 1.275061e-05 -1.814291e-04
## strata(event)event=2 -5.206198e-06 2.425032e-05
## strata(event)event=3 -2.278998e-05 3.234264e-05
## sexF -5.665502e-05 -4.278857e-04
## edad_inicio -7.751782e-07 1.507532e-05
## es_conyugalSeparated -2.208719e-05 9.799655e-05
## es_conyugalSingle -1.370316e-05 -4.139490e-05
## es_conyugalWidower -7.855462e-07 1.224629e-04
## susCocaine 6.152512e-04 2.193761e-04
## susMarijuana 2.193761e-04 2.097638e-03
## susOther 2.066548e-04 4.146021e-04
## susCocaine paste 2.902775e-04 1.277152e-04
## escolaridadSecundaria o menor 2.538481e-05 4.158997e-06
## escolaridadPrimaria o menor 4.568499e-05 6.518533e-05
## compromiso_biopsicosocialModerate -9.106987e-05 -1.534585e-04
## compromiso_biopsicosocialSevere -9.861328e-05 1.521767e-05
## tipo_programaEM 2.407495e-05 3.178031e-04
## estatus_ocupacional2 3.699694e-05 1.865041e-04
## estatus_ocupacional3 4.805435e-05 1.601049e-04
## freq_cons2 -2.537539e-05 1.735507e-06
## freq_cons3 -7.605683e-05 6.746383e-04
## freq_cons4 1.648867e-05 -2.289113e-04
## freq_cons5 9.334937e-06 -3.101761e-05
## freq_cons6 4.066360e-05 -1.029668e-04
## edad_al_ing 6.886987e-06 -2.249501e-06
## terap_disTerapeutic discharge:strata(event)event=2 -4.104838e-06 1.516168e-04
## terap_disTerapeutic discharge:strata(event)event=3 -1.399105e-05 1.870764e-04
## susOther
## terap_disTerapeutic discharge -3.938972e-04
## strata(event)event=2 -3.415253e-05
## strata(event)event=3 -4.697453e-06
## sexF -6.702606e-04
## edad_inicio 1.956684e-05
## es_conyugalSeparated 4.425482e-05
## es_conyugalSingle -2.049115e-04
## es_conyugalWidower -7.158916e-05
## susCocaine 2.066548e-04
## susMarijuana 4.146021e-04
## susOther 4.911409e-03
## susCocaine paste -3.072071e-05
## escolaridadSecundaria o menor -1.446839e-04
## escolaridadPrimaria o menor 5.396270e-05
## compromiso_biopsicosocialModerate 7.344868e-05
## compromiso_biopsicosocialSevere 3.319556e-04
## tipo_programaEM 5.416499e-04
## estatus_ocupacional2 3.016645e-04
## estatus_ocupacional3 2.701997e-04
## freq_cons2 1.097729e-04
## freq_cons3 1.834460e-04
## freq_cons4 -3.739585e-04
## freq_cons5 -5.734277e-06
## freq_cons6 -1.481298e-04
## edad_al_ing -8.460642e-06
## terap_disTerapeutic discharge:strata(event)event=2 3.371726e-04
## terap_disTerapeutic discharge:strata(event)event=3 4.103269e-04
## susCocaine paste
## terap_disTerapeutic discharge 2.633661e-04
## strata(event)event=2 -1.852791e-05
## strata(event)event=3 -7.197267e-05
## sexF 4.895966e-04
## edad_inicio -2.144882e-05
## es_conyugalSeparated -6.504150e-05
## es_conyugalSingle 1.503301e-04
## es_conyugalWidower -3.509456e-05
## susCocaine 2.902775e-04
## susMarijuana 1.277152e-04
## susOther -3.072071e-05
## susCocaine paste 6.688021e-04
## escolaridadSecundaria o menor 1.587837e-04
## escolaridadPrimaria o menor 1.988479e-05
## compromiso_biopsicosocialModerate -2.432580e-04
## compromiso_biopsicosocialSevere -4.476001e-04
## tipo_programaEM -3.896781e-04
## estatus_ocupacional2 -1.106334e-04
## estatus_ocupacional3 -2.271521e-04
## freq_cons2 -5.302281e-05
## freq_cons3 2.252039e-05
## freq_cons4 3.628614e-04
## freq_cons5 5.017685e-05
## freq_cons6 1.239848e-04
## edad_al_ing 1.595608e-05
## terap_disTerapeutic discharge:strata(event)event=2 -2.097954e-04
## terap_disTerapeutic discharge:strata(event)event=3 -2.288029e-04
## escolaridadSecundaria o menor
## terap_disTerapeutic discharge 2.779500e-04
## strata(event)event=2 2.946047e-05
## strata(event)event=3 3.329137e-05
## sexF 4.099800e-04
## edad_inicio -1.601728e-05
## es_conyugalSeparated -1.835553e-05
## es_conyugalSingle 1.333297e-04
## es_conyugalWidower -2.289360e-05
## susCocaine 2.538481e-05
## susMarijuana 4.158997e-06
## susOther -1.446839e-04
## susCocaine paste 1.587837e-04
## escolaridadSecundaria o menor 5.357772e-04
## escolaridadPrimaria o menor 3.179669e-04
## compromiso_biopsicosocialModerate -4.430553e-05
## compromiso_biopsicosocialSevere -2.149535e-04
## tipo_programaEM -3.024164e-04
## estatus_ocupacional2 -1.586387e-04
## estatus_ocupacional3 -2.338518e-04
## freq_cons2 -4.033886e-05
## freq_cons3 1.037933e-04
## freq_cons4 2.854202e-04
## freq_cons5 2.538823e-05
## freq_cons6 7.240928e-05
## edad_al_ing 5.608425e-06
## terap_disTerapeutic discharge:strata(event)event=2 -2.307234e-04
## terap_disTerapeutic discharge:strata(event)event=3 -2.911802e-04
## escolaridadPrimaria o menor
## terap_disTerapeutic discharge 1.411078e-04
## strata(event)event=2 2.774271e-05
## strata(event)event=3 4.099458e-05
## sexF 1.727695e-05
## edad_inicio -5.217762e-07
## es_conyugalSeparated 3.606385e-05
## es_conyugalSingle 8.165930e-05
## es_conyugalWidower -4.305278e-05
## susCocaine 4.568499e-05
## susMarijuana 6.518533e-05
## susOther 5.396270e-05
## susCocaine paste 1.988479e-05
## escolaridadSecundaria o menor 3.179669e-04
## escolaridadPrimaria o menor 6.012040e-04
## compromiso_biopsicosocialModerate 7.594641e-05
## compromiso_biopsicosocialSevere 4.972562e-05
## tipo_programaEM -2.872817e-05
## estatus_ocupacional2 1.053962e-05
## estatus_ocupacional3 -4.662860e-05
## freq_cons2 1.596601e-05
## freq_cons3 1.590787e-04
## freq_cons4 4.865286e-05
## freq_cons5 1.815516e-05
## freq_cons6 3.044177e-05
## edad_al_ing -6.162446e-07
## terap_disTerapeutic discharge:strata(event)event=2 -1.064324e-04
## terap_disTerapeutic discharge:strata(event)event=3 -1.559777e-04
## compromiso_biopsicosocialModerate
## terap_disTerapeutic discharge 7.697965e-04
## strata(event)event=2 1.127785e-04
## strata(event)event=3 8.692001e-05
## sexF 4.729041e-04
## edad_inicio -1.583868e-05
## es_conyugalSeparated 2.936017e-04
## es_conyugalSingle 2.537843e-04
## es_conyugalWidower 3.759992e-04
## susCocaine -9.106987e-05
## susMarijuana -1.534585e-04
## susOther 7.344868e-05
## susCocaine paste -2.432580e-04
## escolaridadSecundaria o menor -4.430553e-05
## escolaridadPrimaria o menor 7.594641e-05
## compromiso_biopsicosocialModerate 2.828737e-03
## compromiso_biopsicosocialSevere 2.696852e-03
## tipo_programaEM -4.770670e-04
## estatus_ocupacional2 -3.354823e-04
## estatus_ocupacional3 -2.563640e-04
## freq_cons2 2.432547e-04
## freq_cons3 -7.773168e-06
## freq_cons4 4.921178e-05
## freq_cons5 -3.296907e-04
## freq_cons6 -5.804977e-04
## edad_al_ing -1.574069e-05
## terap_disTerapeutic discharge:strata(event)event=2 -7.125287e-04
## terap_disTerapeutic discharge:strata(event)event=3 -6.865186e-04
## compromiso_biopsicosocialSevere
## terap_disTerapeutic discharge 4.805736e-04
## strata(event)event=2 6.775931e-05
## strata(event)event=3 5.696462e-05
## sexF -2.397605e-05
## edad_inicio 8.248387e-06
## es_conyugalSeparated 3.069970e-04
## es_conyugalSingle 1.192701e-04
## es_conyugalWidower 3.567035e-04
## susCocaine -9.861328e-05
## susMarijuana 1.521767e-05
## susOther 3.319556e-04
## susCocaine paste -4.476001e-04
## escolaridadSecundaria o menor -2.149535e-04
## escolaridadPrimaria o menor 4.972562e-05
## compromiso_biopsicosocialModerate 2.696852e-03
## compromiso_biopsicosocialSevere 3.039715e-03
## tipo_programaEM -1.633340e-04
## estatus_ocupacional2 -5.721999e-05
## estatus_ocupacional3 9.557822e-06
## freq_cons2 2.666924e-04
## freq_cons3 -2.679264e-05
## freq_cons4 -2.862494e-04
## freq_cons5 -3.878953e-04
## freq_cons6 -7.070047e-04
## edad_al_ing -2.146806e-05
## terap_disTerapeutic discharge:strata(event)event=2 -4.577111e-04
## terap_disTerapeutic discharge:strata(event)event=3 -4.126233e-04
## tipo_programaEM
## terap_disTerapeutic discharge -7.425342e-04
## strata(event)event=2 -8.521223e-05
## strata(event)event=3 -5.676817e-05
## sexF -1.497100e-03
## edad_inicio 4.681092e-05
## es_conyugalSeparated -2.229892e-05
## es_conyugalSingle -4.098608e-04
## es_conyugalWidower -9.580010e-05
## susCocaine 2.407495e-05
## susMarijuana 3.178031e-04
## susOther 5.416499e-04
## susCocaine paste -3.896781e-04
## escolaridadSecundaria o menor -3.024164e-04
## escolaridadPrimaria o menor -2.872817e-05
## compromiso_biopsicosocialModerate -4.770670e-04
## compromiso_biopsicosocialSevere -1.633340e-04
## tipo_programaEM 1.632345e-03
## estatus_ocupacional2 5.009474e-04
## estatus_ocupacional3 6.328112e-04
## freq_cons2 3.245450e-05
## freq_cons3 1.047425e-05
## freq_cons4 -6.985413e-04
## freq_cons5 3.241504e-06
## freq_cons6 -4.780878e-05
## edad_al_ing -1.195260e-05
## terap_disTerapeutic discharge:strata(event)event=2 6.446415e-04
## terap_disTerapeutic discharge:strata(event)event=3 6.721233e-04
## estatus_ocupacional2
## terap_disTerapeutic discharge -3.657213e-04
## strata(event)event=2 -3.149736e-05
## strata(event)event=3 5.593456e-06
## sexF -6.291510e-04
## edad_inicio 2.508371e-05
## es_conyugalSeparated -2.394750e-05
## es_conyugalSingle -1.476197e-04
## es_conyugalWidower -6.641073e-05
## susCocaine 3.699694e-05
## susMarijuana 1.865041e-04
## susOther 3.016645e-04
## susCocaine paste -1.106334e-04
## escolaridadSecundaria o menor -1.586387e-04
## escolaridadPrimaria o menor 1.053962e-05
## compromiso_biopsicosocialModerate -3.354823e-04
## compromiso_biopsicosocialSevere -5.721999e-05
## tipo_programaEM 5.009474e-04
## estatus_ocupacional2 6.467421e-04
## estatus_ocupacional3 4.797349e-04
## freq_cons2 -2.853321e-05
## freq_cons3 -3.248366e-05
## freq_cons4 -3.944518e-04
## freq_cons5 2.439418e-05
## freq_cons6 6.306495e-05
## edad_al_ing -4.037779e-06
## terap_disTerapeutic discharge:strata(event)event=2 3.367921e-04
## terap_disTerapeutic discharge:strata(event)event=3 3.094838e-04
## estatus_ocupacional3
## terap_disTerapeutic discharge -4.941136e-04
## strata(event)event=2 -5.945371e-05
## strata(event)event=3 -3.032579e-05
## sexF -8.841367e-04
## edad_inicio 2.836171e-05
## es_conyugalSeparated 1.355837e-05
## es_conyugalSingle -2.429409e-04
## es_conyugalWidower -9.363211e-05
## susCocaine 4.805435e-05
## susMarijuana 1.601049e-04
## susOther 2.701997e-04
## susCocaine paste -2.271521e-04
## escolaridadSecundaria o menor -2.338518e-04
## escolaridadPrimaria o menor -4.662860e-05
## compromiso_biopsicosocialModerate -2.563640e-04
## compromiso_biopsicosocialSevere 9.557822e-06
## tipo_programaEM 6.328112e-04
## estatus_ocupacional2 4.797349e-04
## estatus_ocupacional3 8.672873e-04
## freq_cons2 1.560853e-05
## freq_cons3 -6.323687e-05
## freq_cons4 -4.828491e-04
## freq_cons5 9.722997e-06
## freq_cons6 -1.493089e-05
## edad_al_ing -7.778289e-06
## terap_disTerapeutic discharge:strata(event)event=2 4.440565e-04
## terap_disTerapeutic discharge:strata(event)event=3 4.239529e-04
## freq_cons2 freq_cons3
## terap_disTerapeutic discharge 2.669706e-05 6.548132e-05
## strata(event)event=2 3.746010e-05 7.280202e-05
## strata(event)event=3 2.522699e-05 7.489597e-05
## sexF 5.699637e-06 2.344919e-05
## edad_inicio -2.999061e-06 -7.253675e-06
## es_conyugalSeparated 4.336851e-05 9.306991e-05
## es_conyugalSingle -1.673272e-06 1.051006e-04
## es_conyugalWidower 6.330174e-05 1.339900e-04
## susCocaine -2.537539e-05 -7.605683e-05
## susMarijuana 1.735507e-06 6.746383e-04
## susOther 1.097729e-04 1.834460e-04
## susCocaine paste -5.302281e-05 2.252039e-05
## escolaridadSecundaria o menor -4.033886e-05 1.037933e-04
## escolaridadPrimaria o menor 1.596601e-05 1.590787e-04
## compromiso_biopsicosocialModerate 2.432547e-04 -7.773168e-06
## compromiso_biopsicosocialSevere 2.666924e-04 -2.679264e-05
## tipo_programaEM 3.245450e-05 1.047425e-05
## estatus_ocupacional2 -2.853321e-05 -3.248366e-05
## estatus_ocupacional3 1.560853e-05 -6.323687e-05
## freq_cons2 5.107215e-03 3.490928e-03
## freq_cons3 3.490928e-03 5.301574e-03
## freq_cons4 3.464786e-03 3.517029e-03
## freq_cons5 3.466839e-03 3.458832e-03
## freq_cons6 3.420128e-03 3.441957e-03
## edad_al_ing -1.473935e-06 -4.790741e-06
## terap_disTerapeutic discharge:strata(event)event=2 3.009555e-06 9.322665e-06
## terap_disTerapeutic discharge:strata(event)event=3 3.156435e-05 -4.845100e-05
## freq_cons4 freq_cons5
## terap_disTerapeutic discharge 5.702189e-04 -5.890255e-05
## strata(event)event=2 1.055268e-04 3.308808e-05
## strata(event)event=3 5.985171e-05 2.101616e-05
## sexF 9.685129e-04 5.733385e-05
## edad_inicio -3.863589e-05 -2.941733e-06
## es_conyugalSeparated -5.238441e-05 -6.488761e-05
## es_conyugalSingle 2.462641e-04 -5.129743e-05
## es_conyugalWidower 2.805734e-05 -3.892097e-05
## susCocaine 1.648867e-05 9.334937e-06
## susMarijuana -2.289113e-04 -3.101761e-05
## susOther -3.739585e-04 -5.734277e-06
## susCocaine paste 3.628614e-04 5.017685e-05
## escolaridadSecundaria o menor 2.854202e-04 2.538823e-05
## escolaridadPrimaria o menor 4.865286e-05 1.815516e-05
## compromiso_biopsicosocialModerate 4.921178e-05 -3.296907e-04
## compromiso_biopsicosocialSevere -2.862494e-04 -3.878953e-04
## tipo_programaEM -6.985413e-04 3.241504e-06
## estatus_ocupacional2 -3.944518e-04 2.439418e-05
## estatus_ocupacional3 -4.828491e-04 9.722997e-06
## freq_cons2 3.464786e-03 3.466839e-03
## freq_cons3 3.517029e-03 3.458832e-03
## freq_cons4 4.311894e-03 3.543263e-03
## freq_cons5 3.543263e-03 3.902007e-03
## freq_cons6 3.606340e-03 3.606244e-03
## edad_al_ing 1.213821e-05 3.326760e-06
## terap_disTerapeutic discharge:strata(event)event=2 -4.604287e-04 1.223692e-04
## terap_disTerapeutic discharge:strata(event)event=3 -4.902243e-04 8.810555e-05
## freq_cons6 edad_al_ing
## terap_disTerapeutic discharge -3.263008e-05 2.967897e-06
## strata(event)event=2 2.561342e-05 -1.479737e-06
## strata(event)event=3 1.463989e-05 -2.520571e-06
## sexF 1.304731e-04 1.633980e-05
## edad_inicio -6.881435e-06 -1.064923e-06
## es_conyugalSeparated -1.203665e-04 -7.580829e-06
## es_conyugalSingle -3.708902e-05 7.144162e-06
## es_conyugalWidower -1.114433e-04 -1.125948e-05
## susCocaine 4.066360e-05 6.886987e-06
## susMarijuana -1.029668e-04 -2.249501e-06
## susOther -1.481298e-04 -8.460642e-06
## susCocaine paste 1.239848e-04 1.595608e-05
## escolaridadSecundaria o menor 7.240928e-05 5.608425e-06
## escolaridadPrimaria o menor 3.044177e-05 -6.162446e-07
## compromiso_biopsicosocialModerate -5.804977e-04 -1.574069e-05
## compromiso_biopsicosocialSevere -7.070047e-04 -2.146806e-05
## tipo_programaEM -4.780878e-05 -1.195260e-05
## estatus_ocupacional2 6.306495e-05 -4.037779e-06
## estatus_ocupacional3 -1.493089e-05 -7.778289e-06
## freq_cons2 3.420128e-03 -1.473935e-06
## freq_cons3 3.441957e-03 -4.790741e-06
## freq_cons4 3.606340e-03 1.213821e-05
## freq_cons5 3.606244e-03 3.326760e-06
## freq_cons6 3.826675e-03 7.547410e-06
## edad_al_ing 7.547410e-06 1.252860e-06
## terap_disTerapeutic discharge:strata(event)event=2 8.916985e-05 -3.458177e-06
## terap_disTerapeutic discharge:strata(event)event=3 4.031576e-05 -4.267159e-06
## terap_disTerapeutic discharge:strata(event)event=2
## terap_disTerapeutic discharge -1.205693e-03
## strata(event)event=2 -4.799037e-04
## strata(event)event=3 -1.652073e-04
## sexF -8.199747e-04
## edad_inicio 3.242230e-05
## es_conyugalSeparated -7.080377e-05
## es_conyugalSingle -3.436757e-04
## es_conyugalWidower -1.508448e-04
## susCocaine -4.104838e-06
## susMarijuana 1.516168e-04
## susOther 3.371726e-04
## susCocaine paste -2.097954e-04
## escolaridadSecundaria o menor -2.307234e-04
## escolaridadPrimaria o menor -1.064324e-04
## compromiso_biopsicosocialModerate -7.125287e-04
## compromiso_biopsicosocialSevere -4.577111e-04
## tipo_programaEM 6.446415e-04
## estatus_ocupacional2 3.367921e-04
## estatus_ocupacional3 4.440565e-04
## freq_cons2 3.009555e-06
## freq_cons3 9.322665e-06
## freq_cons4 -4.604287e-04
## freq_cons5 1.223692e-04
## freq_cons6 8.916985e-05
## edad_al_ing -3.458177e-06
## terap_disTerapeutic discharge:strata(event)event=2 2.673876e-03
## terap_disTerapeutic discharge:strata(event)event=3 1.154604e-03
## terap_disTerapeutic discharge:strata(event)event=3
## terap_disTerapeutic discharge -1.249682e-03
## strata(event)event=2 -2.040180e-04
## strata(event)event=3 -1.191342e-03
## sexF -8.604603e-04
## edad_inicio 3.840462e-05
## es_conyugalSeparated -5.981260e-05
## es_conyugalSingle -3.725628e-04
## es_conyugalWidower -1.335706e-04
## susCocaine -1.399105e-05
## susMarijuana 1.870764e-04
## susOther 4.103269e-04
## susCocaine paste -2.288029e-04
## escolaridadSecundaria o menor -2.911802e-04
## escolaridadPrimaria o menor -1.559777e-04
## compromiso_biopsicosocialModerate -6.865186e-04
## compromiso_biopsicosocialSevere -4.126233e-04
## tipo_programaEM 6.721233e-04
## estatus_ocupacional2 3.094838e-04
## estatus_ocupacional3 4.239529e-04
## freq_cons2 3.156435e-05
## freq_cons3 -4.845100e-05
## freq_cons4 -4.902243e-04
## freq_cons5 8.810555e-05
## freq_cons6 4.031576e-05
## edad_al_ing -4.267159e-06
## terap_disTerapeutic discharge:strata(event)event=2 1.154604e-03
## terap_disTerapeutic discharge:strata(event)event=3 6.121920e-03
##
## Generalized concordance probability:
## concordance prob. lower 0.95
## terap_disTerapeutic discharge 0.4668 0.4493
## strata(event)event=2 0.6196 0.6104
## strata(event)event=3 0.6780 0.6635
## sexF 0.5577 0.5363
## edad_inicio 0.4961 0.4949
## es_conyugalSeparated 0.4959 0.4825
## es_conyugalSingle 0.4954 0.4845
## es_conyugalWidower 0.4733 0.4361
## susCocaine 0.5446 0.5326
## susMarijuana 0.4696 0.4474
## susOther 0.4939 0.4596
## susCocaine paste 0.5862 0.5738
## escolaridadSecundaria o menor 0.4841 0.4728
## escolaridadPrimaria o menor 0.4398 0.4280
## compromiso_biopsicosocialModerate 0.5119 0.4858
## compromiso_biopsicosocialSevere 0.5518 0.5249
## tipo_programaEM 0.5508 0.5311
## estatus_ocupacional2 0.4790 0.4665
## estatus_ocupacional3 0.4860 0.4716
## freq_cons2 0.5067 0.4717
## freq_cons3 0.5376 0.5020
## freq_cons4 0.5373 0.5052
## freq_cons5 0.5321 0.5015
## freq_cons6 0.5379 0.5077
## edad_al_ing 0.4981 0.4976
## terap_disTerapeutic discharge:strata(event)event=2 0.4924 0.4671
## terap_disTerapeutic discharge:strata(event)event=3 0.4910 0.4528
## upper 0.95
## terap_disTerapeutic discharge 0.4845
## strata(event)event=2 0.6288
## strata(event)event=3 0.6922
## sexF 0.5789
## edad_inicio 0.4973
## es_conyugalSeparated 0.5093
## es_conyugalSingle 0.5063
## es_conyugalWidower 0.5108
## susCocaine 0.5567
## susMarijuana 0.4920
## susOther 0.5282
## susCocaine paste 0.5984
## escolaridadSecundaria o menor 0.4955
## escolaridadPrimaria o menor 0.4517
## compromiso_biopsicosocialModerate 0.5379
## compromiso_biopsicosocialSevere 0.5783
## tipo_programaEM 0.5703
## estatus_ocupacional2 0.4914
## estatus_ocupacional3 0.5005
## freq_cons2 0.5416
## freq_cons3 0.5729
## freq_cons4 0.5691
## freq_cons5 0.5624
## freq_cons6 0.5679
## edad_al_ing 0.4987
## terap_disTerapeutic discharge:strata(event)event=2 0.5177
## terap_disTerapeutic discharge:strata(event)event=3 0.5293conc_gt_3_cl <- cbind.data.frame(conc_prob=concord(pwp_gt_imp3_cl)[,1],
lo_ci95=concord(pwp_gt_imp3_cl)[,2],
up_ci95=concord(pwp_gt_imp3_cl)[,3],
conc_p=summary(pwp_gt_imp3_cl, print = FALSE)$prob)%>%
data.table::data.table(keep.rownames=T)
res_gt_2_orig <- cbind.data.frame(HR=round(exp(coef(pwp_gt_imp_2)),2),
Lo_CI95=round(exp(confint(pwp_gt_imp_2)[,1]),2),
Up_CI95=round(exp(confint(pwp_gt_imp_2)[,2]),2))%>%
data.table::data.table(keep.rownames=T)
# res_tt_2 <- cbind.data.frame(HR=round(exp(pwp_tt_imp2$coeff),2),
# Lo_ci95=round(exp(confint(pwp_tt_imp2))[,1],2),
# Up_ci95=round(exp(confint(pwp_tt_imp2))[,2],2),
# p=round(summary(pwp_tt_imp2)$prob,4)) %>%
# data.table::data.table(keep.rownames=T)
res_tt_2_cl <- cbind.data.frame(HR=round(exp(pwp_tt_imp2_cl$coeff),2),
Lo_ci95=round(exp(confint(pwp_tt_imp2_cl))[,1],2),
Up_ci95=round(exp(confint(pwp_tt_imp2_cl))[,2],2),
p=round(summary(pwp_tt_imp2_cl)$prob,4)) %>%
data.table::data.table(keep.rownames=T)## coxphw(formula = Surv(tstart, tstop, status == 1) ~ terap_dis *
## strata(event) + sex + edad_inicio + es_conyugal + sus + escolaridad +
## compromiso_biopsicosocial + tipo_programa + estatus_ocupacional +
## freq_cons + edad_al_ing + strata(event), data = rfimp2, template = "PH",
## robust = TRUE, clusterid = rfimp2$id)
##
## Model fitted by unweighted estimation (PH template)
##
## coef se(coef)
## terap_disTerapeutic discharge -0.2408759154 0.0195576467
## strata(event)event=2 0.7413651927 0.0196459468
## strata(event)event=3 1.0899882234 0.0339301204
## sexF 0.1958529551 0.0195787865
## edad_inicio -0.0119905820 0.0016282485
## es_conyugalSeparated 0.0022100675 0.0245231361
## es_conyugalSingle -0.0288061090 0.0160588389
## es_conyugalWidower -0.1082845376 0.0735749282
## susCocaine 0.1736475203 0.0223205021
## susMarijuana -0.1529125837 0.0346372303
## susOther -0.0421876632 0.0589173960
## susCocaine paste 0.3189779805 0.0190285059
## escolaridadSecundaria o menor -0.0907181491 0.0186488098
## escolaridadPrimaria o menor -0.2713931283 0.0217408564
## compromiso_biopsicosocialModerate 0.0661587929 0.0288189273
## compromiso_biopsicosocialSevere 0.2634985242 0.0309718571
## tipo_programaEM 0.2513310689 0.0244062205
## estatus_ocupacional2 -0.0949893411 0.0164806127
## estatus_ocupacional3 -0.0399234421 0.0196532115
## freq_cons2 0.0492848298 0.0690149839
## freq_cons3 0.0804384978 0.0639743212
## freq_cons4 0.1095349527 0.0591217224
## freq_cons5 0.1186868173 0.0601001797
## freq_cons6 0.1348530898 0.0586329774
## edad_al_ing -0.0076502315 0.0008253058
## terap_disTerapeutic discharge:strata(event)event=2 0.0002866275 0.0425166434
## terap_disTerapeutic discharge:strata(event)event=3 0.0598834155 0.0739249805
## exp(coef) lower 0.95
## terap_disTerapeutic discharge 0.7859391 0.7563824
## strata(event)event=2 2.0987988 2.0195200
## strata(event)event=3 2.9742390 2.7828801
## sexF 1.2163480 1.1705565
## edad_inicio 0.9880810 0.9849328
## es_conyugalSeparated 1.0022125 0.9551810
## es_conyugalSingle 0.9716048 0.9415001
## es_conyugalWidower 0.8973722 0.7768650
## susCocaine 1.1896362 1.1387147
## susMarijuana 0.8582047 0.8018768
## susOther 0.9586899 0.8541370
## susCocaine paste 1.3757210 1.3253582
## escolaridadSecundaria o menor 0.9132751 0.8804967
## escolaridadPrimaria o menor 0.7623167 0.7305158
## compromiso_biopsicosocialModerate 1.0683964 1.0097217
## compromiso_biopsicosocialSevere 1.3014754 1.2248211
## tipo_programaEM 1.2857357 1.2256800
## estatus_ocupacional2 0.9093826 0.8804776
## estatus_ocupacional3 0.9608630 0.9245547
## freq_cons2 1.0505195 0.9176107
## freq_cons3 1.0837622 0.9560464
## freq_cons4 1.1157591 0.9936786
## freq_cons5 1.1260172 1.0008930
## freq_cons6 1.1443687 1.0201346
## edad_al_ing 0.9923790 0.9907750
## terap_disTerapeutic discharge:strata(event)event=2 1.0002867 0.9203102
## terap_disTerapeutic discharge:strata(event)event=3 1.0617128 0.9185060
## upper 0.95 z
## terap_disTerapeutic discharge 0.8166508 -12.316201373
## strata(event)event=2 2.1811899 37.736292400
## strata(event)event=3 3.1787564 32.124502056
## sexF 1.2639310 10.003324495
## edad_inicio 0.9912393 -7.364098395
## es_conyugalSeparated 1.0515597 0.090121733
## es_conyugalSingle 1.0026722 -1.793785289
## es_conyugalWidower 1.0365726 -1.471758658
## susCocaine 1.2428348 7.779731828
## susMarijuana 0.9184895 -4.414688541
## susOther 1.0760407 -0.716047654
## susCocaine paste 1.4279976 16.763164810
## escolaridadSecundaria o menor 0.9472738 -4.864554358
## escolaridadPrimaria o menor 0.7955021 -12.483092825
## compromiso_biopsicosocialModerate 1.1304806 2.295671603
## compromiso_biopsicosocialSevere 1.3829270 8.507675956
## tipo_programaEM 1.3487340 10.297828315
## estatus_ocupacional2 0.9392365 -5.763702032
## estatus_ocupacional3 0.9985971 -2.031395334
## freq_cons2 1.2026792 0.714117819
## freq_cons3 1.2285393 1.257356018
## freq_cons4 1.2528380 1.852702326
## freq_cons5 1.2667835 1.974816347
## freq_cons6 1.2837322 2.299952956
## edad_al_ing 0.9939855 -9.269572324
## terap_disTerapeutic discharge:strata(event)event=2 1.0872132 0.006741537
## terap_disTerapeutic discharge:strata(event)event=3 1.2272473 0.810056562
## p
## terap_disTerapeutic discharge 0.000000e+00
## strata(event)event=2 0.000000e+00
## strata(event)event=3 0.000000e+00
## sexF 0.000000e+00
## edad_inicio 1.783018e-13
## es_conyugalSeparated 9.281905e-01
## es_conyugalSingle 7.284745e-02
## es_conyugalWidower 1.410861e-01
## susCocaine 7.216450e-15
## susMarijuana 1.011555e-05
## susOther 4.739619e-01
## susCocaine paste 0.000000e+00
## escolaridadSecundaria o menor 1.147150e-06
## escolaridadPrimaria o menor 0.000000e+00
## compromiso_biopsicosocialModerate 2.169467e-02
## compromiso_biopsicosocialSevere 0.000000e+00
## tipo_programaEM 0.000000e+00
## estatus_ocupacional2 8.228864e-09
## estatus_ocupacional3 4.221491e-02
## freq_cons2 4.751543e-01
## freq_cons3 2.086247e-01
## freq_cons4 6.392504e-02
## freq_cons5 4.828899e-02
## freq_cons6 2.145089e-02
## edad_al_ing 0.000000e+00
## terap_disTerapeutic discharge:strata(event)event=2 9.946211e-01
## terap_disTerapeutic discharge:strata(event)event=3 4.179077e-01
##
## Wald Chi-square = 6815.147 on 27 df p = 0 n = 107665
##
## Covariance-Matrix:
## terap_disTerapeutic discharge
## terap_disTerapeutic discharge 3.825015e-04
## strata(event)event=2 7.786239e-05
## strata(event)event=3 7.289501e-05
## sexF -7.543787e-06
## edad_inicio -2.647637e-07
## es_conyugalSeparated 1.630572e-07
## es_conyugalSingle 6.155073e-06
## es_conyugalWidower 2.034014e-05
## susCocaine 2.106522e-05
## susMarijuana 3.328502e-06
## susOther -1.667121e-05
## susCocaine paste 2.508898e-05
## escolaridadSecundaria o menor 2.034476e-05
## escolaridadPrimaria o menor 3.302071e-05
## compromiso_biopsicosocialModerate 2.080338e-05
## compromiso_biopsicosocialSevere 1.903664e-05
## tipo_programaEM -8.788530e-06
## estatus_ocupacional2 -2.596602e-06
## estatus_ocupacional3 -1.717451e-06
## freq_cons2 -2.472373e-06
## freq_cons3 -7.866428e-06
## freq_cons4 8.162247e-07
## freq_cons5 1.076952e-07
## freq_cons6 2.315740e-06
## edad_al_ing -1.136091e-06
## terap_disTerapeutic discharge:strata(event)event=2 -3.692285e-04
## terap_disTerapeutic discharge:strata(event)event=3 -4.055398e-04
## strata(event)event=2
## terap_disTerapeutic discharge 7.786239e-05
## strata(event)event=2 3.859632e-04
## strata(event)event=3 1.002251e-04
## sexF -1.499980e-05
## edad_inicio 1.969454e-06
## es_conyugalSeparated -8.673653e-06
## es_conyugalSingle -5.482976e-06
## es_conyugalWidower 3.366719e-08
## susCocaine -7.039327e-06
## susMarijuana 8.593786e-06
## susOther 9.044579e-06
## susCocaine paste -2.532815e-05
## escolaridadSecundaria o menor -2.996165e-06
## escolaridadPrimaria o menor 1.175387e-05
## compromiso_biopsicosocialModerate -5.466040e-06
## compromiso_biopsicosocialSevere -1.843269e-05
## tipo_programaEM -1.472051e-05
## estatus_ocupacional2 4.866628e-06
## estatus_ocupacional3 -5.734511e-06
## freq_cons2 3.300380e-05
## freq_cons3 2.640852e-05
## freq_cons4 4.084726e-05
## freq_cons5 3.760339e-05
## freq_cons6 3.510156e-05
## edad_al_ing -1.144855e-06
## terap_disTerapeutic discharge:strata(event)event=2 -3.759742e-04
## terap_disTerapeutic discharge:strata(event)event=3 -7.978350e-05
## strata(event)event=3
## terap_disTerapeutic discharge 7.289501e-05
## strata(event)event=2 1.002251e-04
## strata(event)event=3 1.151253e-03
## sexF -2.619427e-05
## edad_inicio 2.646149e-06
## es_conyugalSeparated 1.186424e-05
## es_conyugalSingle 8.339745e-06
## es_conyugalWidower -1.668821e-05
## susCocaine -2.895780e-05
## susMarijuana -1.000897e-05
## susOther 1.063392e-05
## susCocaine paste -6.489520e-05
## escolaridadSecundaria o menor 1.532454e-05
## escolaridadPrimaria o menor 3.065769e-05
## compromiso_biopsicosocialModerate -7.964043e-06
## compromiso_biopsicosocialSevere -2.371485e-05
## tipo_programaEM -2.777681e-05
## estatus_ocupacional2 1.773335e-05
## estatus_ocupacional3 6.589829e-07
## freq_cons2 1.954294e-05
## freq_cons3 9.462408e-06
## freq_cons4 1.766349e-05
## freq_cons5 2.207674e-05
## freq_cons6 2.188013e-05
## edad_al_ing -1.764260e-06
## terap_disTerapeutic discharge:strata(event)event=2 -7.281422e-05
## terap_disTerapeutic discharge:strata(event)event=3 -1.119579e-03
## sexF edad_inicio
## terap_disTerapeutic discharge -7.543787e-06 -2.647637e-07
## strata(event)event=2 -1.499980e-05 1.969454e-06
## strata(event)event=3 -2.619427e-05 2.646149e-06
## sexF 3.833289e-04 -5.157751e-06
## edad_inicio -5.157751e-06 2.651193e-06
## es_conyugalSeparated -4.964540e-06 -8.861689e-07
## es_conyugalSingle 1.088960e-05 -5.198367e-08
## es_conyugalWidower -5.389706e-05 -2.839362e-06
## susCocaine -5.164854e-06 -7.104730e-07
## susMarijuana -5.535093e-06 3.366510e-07
## susOther -4.204188e-05 -1.005276e-05
## susCocaine paste 1.212162e-05 -7.959546e-07
## escolaridadSecundaria o menor -2.210523e-07 9.404494e-08
## escolaridadPrimaria o menor -1.185731e-05 2.101592e-06
## compromiso_biopsicosocialModerate -2.181676e-05 1.891589e-06
## compromiso_biopsicosocialSevere -2.220322e-05 3.902071e-06
## tipo_programaEM -2.763869e-04 1.297800e-06
## estatus_ocupacional2 1.871181e-05 5.170864e-07
## estatus_ocupacional3 -7.757845e-05 1.973396e-08
## freq_cons2 3.285614e-05 -3.204905e-06
## freq_cons3 4.481694e-05 -3.280998e-06
## freq_cons4 5.439435e-05 -2.278396e-06
## freq_cons5 5.785364e-05 -1.883904e-06
## freq_cons6 6.563692e-05 -1.605351e-06
## edad_al_ing 1.192243e-06 -3.970343e-07
## terap_disTerapeutic discharge:strata(event)event=2 1.152560e-05 -8.122709e-08
## terap_disTerapeutic discharge:strata(event)event=3 7.050478e-06 2.616813e-06
## es_conyugalSeparated
## terap_disTerapeutic discharge 1.630572e-07
## strata(event)event=2 -8.673653e-06
## strata(event)event=3 1.186424e-05
## sexF -4.964540e-06
## edad_inicio -8.861689e-07
## es_conyugalSeparated 6.013842e-04
## es_conyugalSingle 1.322860e-04
## es_conyugalWidower 1.696905e-04
## susCocaine 1.669792e-05
## susMarijuana 4.772730e-06
## susOther 1.179308e-05
## susCocaine paste 1.117730e-05
## escolaridadSecundaria o menor 1.856622e-05
## escolaridadPrimaria o menor 2.608496e-05
## compromiso_biopsicosocialModerate -1.715061e-05
## compromiso_biopsicosocialSevere -2.707177e-05
## tipo_programaEM -4.420624e-06
## estatus_ocupacional2 1.631697e-05
## estatus_ocupacional3 1.854812e-05
## freq_cons2 2.924883e-06
## freq_cons3 1.807033e-05
## freq_cons4 1.095788e-06
## freq_cons5 -3.855400e-06
## freq_cons6 -7.369282e-06
## edad_al_ing -2.190113e-06
## terap_disTerapeutic discharge:strata(event)event=2 1.116438e-06
## terap_disTerapeutic discharge:strata(event)event=3 -8.200319e-06
## es_conyugalSingle
## terap_disTerapeutic discharge 6.155073e-06
## strata(event)event=2 -5.482976e-06
## strata(event)event=3 8.339745e-06
## sexF 1.088960e-05
## edad_inicio -5.198367e-08
## es_conyugalSeparated 1.322860e-04
## es_conyugalSingle 2.578863e-04
## es_conyugalWidower 1.066513e-04
## susCocaine 1.567403e-05
## susMarijuana -5.822778e-06
## susOther -9.166402e-06
## susCocaine paste 1.566705e-06
## escolaridadSecundaria o menor 1.052907e-05
## escolaridadPrimaria o menor 1.528539e-05
## compromiso_biopsicosocialModerate -9.022347e-06
## compromiso_biopsicosocialSevere -1.810414e-05
## tipo_programaEM -9.719926e-06
## estatus_ocupacional2 3.144022e-05
## estatus_ocupacional3 1.115255e-05
## freq_cons2 4.841453e-06
## freq_cons3 -3.002157e-06
## freq_cons4 -1.216879e-05
## freq_cons5 -1.565657e-05
## freq_cons6 -1.839533e-05
## edad_al_ing 3.570184e-06
## terap_disTerapeutic discharge:strata(event)event=2 -1.100482e-05
## terap_disTerapeutic discharge:strata(event)event=3 -4.054004e-05
## es_conyugalWidower
## terap_disTerapeutic discharge 2.034014e-05
## strata(event)event=2 3.366719e-08
## strata(event)event=3 -1.668821e-05
## sexF -5.389706e-05
## edad_inicio -2.839362e-06
## es_conyugalSeparated 1.696905e-04
## es_conyugalSingle 1.066513e-04
## es_conyugalWidower 5.413270e-03
## susCocaine 5.825252e-05
## susMarijuana -1.836634e-06
## susOther -4.056989e-05
## susCocaine paste 3.360090e-05
## escolaridadSecundaria o menor -2.950678e-06
## escolaridadPrimaria o menor -3.700493e-05
## compromiso_biopsicosocialModerate -1.337681e-05
## compromiso_biopsicosocialSevere -2.528849e-05
## tipo_programaEM 9.230241e-06
## estatus_ocupacional2 1.447662e-05
## estatus_ocupacional3 -3.629233e-05
## freq_cons2 3.239970e-05
## freq_cons3 2.049100e-05
## freq_cons4 1.469927e-05
## freq_cons5 2.619846e-05
## freq_cons6 1.361255e-05
## edad_al_ing -5.011852e-06
## terap_disTerapeutic discharge:strata(event)event=2 -9.236578e-08
## terap_disTerapeutic discharge:strata(event)event=3 -2.028312e-05
## susCocaine susMarijuana
## terap_disTerapeutic discharge 2.106522e-05 3.328502e-06
## strata(event)event=2 -7.039327e-06 8.593786e-06
## strata(event)event=3 -2.895780e-05 -1.000897e-05
## sexF -5.164854e-06 -5.535093e-06
## edad_inicio -7.104730e-07 3.366510e-07
## es_conyugalSeparated 1.669792e-05 4.772730e-06
## es_conyugalSingle 1.567403e-05 -5.822778e-06
## es_conyugalWidower 5.825252e-05 -1.836634e-06
## susCocaine 4.982048e-04 2.487120e-04
## susMarijuana 2.487120e-04 1.199738e-03
## susOther 1.890317e-04 2.303545e-04
## susCocaine paste 2.404440e-04 2.576205e-04
## escolaridadSecundaria o menor 1.663311e-05 1.952620e-05
## escolaridadPrimaria o menor 4.260564e-05 3.786524e-05
## compromiso_biopsicosocialModerate -3.222447e-05 2.945040e-05
## compromiso_biopsicosocialSevere -4.787971e-05 4.597699e-05
## tipo_programaEM 2.707687e-06 1.985922e-05
## estatus_ocupacional2 8.625753e-07 -4.728500e-06
## estatus_ocupacional3 1.759392e-05 -1.835039e-05
## freq_cons2 -1.458214e-05 -3.289384e-06
## freq_cons3 5.362781e-06 1.470414e-05
## freq_cons4 1.425518e-05 7.668309e-06
## freq_cons5 1.118589e-05 -1.262214e-05
## freq_cons6 7.976071e-06 -5.733987e-05
## edad_al_ing 4.539767e-06 6.135423e-06
## terap_disTerapeutic discharge:strata(event)event=2 -1.648251e-05 3.022782e-06
## terap_disTerapeutic discharge:strata(event)event=3 -1.222999e-05 2.243579e-05
## susOther
## terap_disTerapeutic discharge -1.667121e-05
## strata(event)event=2 9.044579e-06
## strata(event)event=3 1.063392e-05
## sexF -4.204188e-05
## edad_inicio -1.005276e-05
## es_conyugalSeparated 1.179308e-05
## es_conyugalSingle -9.166402e-06
## es_conyugalWidower -4.056989e-05
## susCocaine 1.890317e-04
## susMarijuana 2.303545e-04
## susOther 3.471260e-03
## susCocaine paste 2.137899e-04
## escolaridadSecundaria o menor 3.086994e-05
## escolaridadPrimaria o menor 2.874865e-05
## compromiso_biopsicosocialModerate 7.465221e-06
## compromiso_biopsicosocialSevere 1.514421e-05
## tipo_programaEM 2.195800e-05
## estatus_ocupacional2 2.801115e-05
## estatus_ocupacional3 -3.167845e-05
## freq_cons2 7.173783e-05
## freq_cons3 8.355367e-05
## freq_cons4 6.738171e-05
## freq_cons5 5.404988e-05
## freq_cons6 -2.024938e-05
## edad_al_ing 1.872541e-06
## terap_disTerapeutic discharge:strata(event)event=2 1.034930e-05
## terap_disTerapeutic discharge:strata(event)event=3 8.812404e-05
## susCocaine paste
## terap_disTerapeutic discharge 2.508898e-05
## strata(event)event=2 -2.532815e-05
## strata(event)event=3 -6.489520e-05
## sexF 1.212162e-05
## edad_inicio -7.959546e-07
## es_conyugalSeparated 1.117730e-05
## es_conyugalSingle 1.566705e-06
## es_conyugalWidower 3.360090e-05
## susCocaine 2.404440e-04
## susMarijuana 2.576205e-04
## susOther 2.137899e-04
## susCocaine paste 3.620840e-04
## escolaridadSecundaria o menor -1.522523e-05
## escolaridadPrimaria o menor -1.288723e-05
## compromiso_biopsicosocialModerate -4.395041e-05
## compromiso_biopsicosocialSevere -6.728867e-05
## tipo_programaEM -1.207617e-05
## estatus_ocupacional2 3.945715e-05
## estatus_ocupacional3 2.133260e-05
## freq_cons2 1.227952e-05
## freq_cons3 3.000586e-05
## freq_cons4 3.469273e-05
## freq_cons5 1.327864e-05
## freq_cons6 -1.263442e-05
## edad_al_ing 4.513920e-06
## terap_disTerapeutic discharge:strata(event)event=2 -2.932575e-06
## terap_disTerapeutic discharge:strata(event)event=3 -8.704332e-07
## escolaridadSecundaria o menor
## terap_disTerapeutic discharge 2.034476e-05
## strata(event)event=2 -2.996165e-06
## strata(event)event=3 1.532454e-05
## sexF -2.210523e-07
## edad_inicio 9.404494e-08
## es_conyugalSeparated 1.856622e-05
## es_conyugalSingle 1.052907e-05
## es_conyugalWidower -2.950678e-06
## susCocaine 1.663311e-05
## susMarijuana 1.952620e-05
## susOther 3.086994e-05
## susCocaine paste -1.522523e-05
## escolaridadSecundaria o menor 3.477781e-04
## escolaridadPrimaria o menor 2.723969e-04
## compromiso_biopsicosocialModerate -6.864252e-06
## compromiso_biopsicosocialSevere -1.839234e-05
## tipo_programaEM 1.122199e-07
## estatus_ocupacional2 -5.284352e-06
## estatus_ocupacional3 -4.085144e-06
## freq_cons2 -1.939234e-06
## freq_cons3 1.002525e-05
## freq_cons4 4.389373e-06
## freq_cons5 1.082143e-05
## freq_cons6 4.751026e-06
## edad_al_ing 2.024848e-07
## terap_disTerapeutic discharge:strata(event)event=2 1.030224e-05
## terap_disTerapeutic discharge:strata(event)event=3 -5.809521e-05
## escolaridadPrimaria o menor
## terap_disTerapeutic discharge 3.302071e-05
## strata(event)event=2 1.175387e-05
## strata(event)event=3 3.065769e-05
## sexF -1.185731e-05
## edad_inicio 2.101592e-06
## es_conyugalSeparated 2.608496e-05
## es_conyugalSingle 1.528539e-05
## es_conyugalWidower -3.700493e-05
## susCocaine 4.260564e-05
## susMarijuana 3.786524e-05
## susOther 2.874865e-05
## susCocaine paste -1.288723e-05
## escolaridadSecundaria o menor 2.723969e-04
## escolaridadPrimaria o menor 4.726648e-04
## compromiso_biopsicosocialModerate -7.058499e-06
## compromiso_biopsicosocialSevere -3.080977e-05
## tipo_programaEM 1.725116e-06
## estatus_ocupacional2 -8.009247e-06
## estatus_ocupacional3 -2.027244e-05
## freq_cons2 6.090243e-06
## freq_cons3 1.747328e-05
## freq_cons4 1.709995e-05
## freq_cons5 2.644808e-05
## freq_cons6 1.544850e-05
## edad_al_ing -9.020499e-07
## terap_disTerapeutic discharge:strata(event)event=2 4.016063e-06
## terap_disTerapeutic discharge:strata(event)event=3 -6.611391e-05
## compromiso_biopsicosocialModerate
## terap_disTerapeutic discharge 2.080338e-05
## strata(event)event=2 -5.466040e-06
## strata(event)event=3 -7.964043e-06
## sexF -2.181676e-05
## edad_inicio 1.891589e-06
## es_conyugalSeparated -1.715061e-05
## es_conyugalSingle -9.022347e-06
## es_conyugalWidower -1.337681e-05
## susCocaine -3.222447e-05
## susMarijuana 2.945040e-05
## susOther 7.465221e-06
## susCocaine paste -4.395041e-05
## escolaridadSecundaria o menor -6.864252e-06
## escolaridadPrimaria o menor -7.058499e-06
## compromiso_biopsicosocialModerate 8.305306e-04
## compromiso_biopsicosocialSevere 7.762423e-04
## tipo_programaEM 8.705712e-07
## estatus_ocupacional2 1.725426e-05
## estatus_ocupacional3 5.804632e-07
## freq_cons2 6.652355e-05
## freq_cons3 3.023312e-05
## freq_cons4 -5.490466e-05
## freq_cons5 -7.736534e-05
## freq_cons6 -7.402290e-05
## edad_al_ing -2.694886e-07
## terap_disTerapeutic discharge:strata(event)event=2 -7.773101e-06
## terap_disTerapeutic discharge:strata(event)event=3 -1.836635e-05
## compromiso_biopsicosocialSevere
## terap_disTerapeutic discharge 1.903664e-05
## strata(event)event=2 -1.843269e-05
## strata(event)event=3 -2.371485e-05
## sexF -2.220322e-05
## edad_inicio 3.902071e-06
## es_conyugalSeparated -2.707177e-05
## es_conyugalSingle -1.810414e-05
## es_conyugalWidower -2.528849e-05
## susCocaine -4.787971e-05
## susMarijuana 4.597699e-05
## susOther 1.514421e-05
## susCocaine paste -6.728867e-05
## escolaridadSecundaria o menor -1.839234e-05
## escolaridadPrimaria o menor -3.080977e-05
## compromiso_biopsicosocialModerate 7.762423e-04
## compromiso_biopsicosocialSevere 9.592559e-04
## tipo_programaEM -3.643670e-05
## estatus_ocupacional2 5.620649e-05
## estatus_ocupacional3 8.066932e-06
## freq_cons2 7.483732e-05
## freq_cons3 4.217519e-05
## freq_cons4 -5.644985e-05
## freq_cons5 -1.052246e-04
## freq_cons6 -1.316737e-04
## edad_al_ing -5.482559e-07
## terap_disTerapeutic discharge:strata(event)event=2 3.314433e-06
## terap_disTerapeutic discharge:strata(event)event=3 -1.440716e-06
## tipo_programaEM
## terap_disTerapeutic discharge -8.788530e-06
## strata(event)event=2 -1.472051e-05
## strata(event)event=3 -2.777681e-05
## sexF -2.763869e-04
## edad_inicio 1.297800e-06
## es_conyugalSeparated -4.420624e-06
## es_conyugalSingle -9.719926e-06
## es_conyugalWidower 9.230241e-06
## susCocaine 2.707687e-06
## susMarijuana 1.985922e-05
## susOther 2.195800e-05
## susCocaine paste -1.207617e-05
## escolaridadSecundaria o menor 1.122199e-07
## escolaridadPrimaria o menor 1.725116e-06
## compromiso_biopsicosocialModerate 8.705712e-07
## compromiso_biopsicosocialSevere -3.643670e-05
## tipo_programaEM 5.956636e-04
## estatus_ocupacional2 1.275939e-06
## estatus_ocupacional3 -1.132523e-05
## freq_cons2 1.505889e-05
## freq_cons3 7.935430e-06
## freq_cons4 -4.476405e-06
## freq_cons5 -1.134775e-05
## freq_cons6 -1.803222e-05
## edad_al_ing 4.057912e-07
## terap_disTerapeutic discharge:strata(event)event=2 -2.963110e-06
## terap_disTerapeutic discharge:strata(event)event=3 -4.358711e-07
## estatus_ocupacional2
## terap_disTerapeutic discharge -2.596602e-06
## strata(event)event=2 4.866628e-06
## strata(event)event=3 1.773335e-05
## sexF 1.871181e-05
## edad_inicio 5.170864e-07
## es_conyugalSeparated 1.631697e-05
## es_conyugalSingle 3.144022e-05
## es_conyugalWidower 1.447662e-05
## susCocaine 8.625753e-07
## susMarijuana -4.728500e-06
## susOther 2.801115e-05
## susCocaine paste 3.945715e-05
## escolaridadSecundaria o menor -5.284352e-06
## escolaridadPrimaria o menor -8.009247e-06
## compromiso_biopsicosocialModerate 1.725426e-05
## compromiso_biopsicosocialSevere 5.620649e-05
## tipo_programaEM 1.275939e-06
## estatus_ocupacional2 2.716106e-04
## estatus_ocupacional3 1.176483e-04
## freq_cons2 -2.983547e-06
## freq_cons3 -3.903963e-06
## freq_cons4 -1.929985e-06
## freq_cons5 2.190934e-05
## freq_cons6 3.644798e-05
## edad_al_ing -7.240217e-07
## terap_disTerapeutic discharge:strata(event)event=2 7.253046e-06
## terap_disTerapeutic discharge:strata(event)event=3 -1.047178e-05
## estatus_ocupacional3
## terap_disTerapeutic discharge -1.717451e-06
## strata(event)event=2 -5.734511e-06
## strata(event)event=3 6.589829e-07
## sexF -7.757845e-05
## edad_inicio 1.973396e-08
## es_conyugalSeparated 1.854812e-05
## es_conyugalSingle 1.115255e-05
## es_conyugalWidower -3.629233e-05
## susCocaine 1.759392e-05
## susMarijuana -1.835039e-05
## susOther -3.167845e-05
## susCocaine paste 2.133260e-05
## escolaridadSecundaria o menor -4.085144e-06
## escolaridadPrimaria o menor -2.027244e-05
## compromiso_biopsicosocialModerate 5.804632e-07
## compromiso_biopsicosocialSevere 8.066932e-06
## tipo_programaEM -1.132523e-05
## estatus_ocupacional2 1.176483e-04
## estatus_ocupacional3 3.862487e-04
## freq_cons2 -1.724002e-06
## freq_cons3 2.505712e-06
## freq_cons4 -2.031447e-07
## freq_cons5 7.908139e-06
## freq_cons6 5.102790e-06
## edad_al_ing -5.378214e-07
## terap_disTerapeutic discharge:strata(event)event=2 2.708434e-06
## terap_disTerapeutic discharge:strata(event)event=3 -2.543446e-05
## freq_cons2 freq_cons3
## terap_disTerapeutic discharge -2.472373e-06 -7.866428e-06
## strata(event)event=2 3.300380e-05 2.640852e-05
## strata(event)event=3 1.954294e-05 9.462408e-06
## sexF 3.285614e-05 4.481694e-05
## edad_inicio -3.204905e-06 -3.280998e-06
## es_conyugalSeparated 2.924883e-06 1.807033e-05
## es_conyugalSingle 4.841453e-06 -3.002157e-06
## es_conyugalWidower 3.239970e-05 2.049100e-05
## susCocaine -1.458214e-05 5.362781e-06
## susMarijuana -3.289384e-06 1.470414e-05
## susOther 7.173783e-05 8.355367e-05
## susCocaine paste 1.227952e-05 3.000586e-05
## escolaridadSecundaria o menor -1.939234e-06 1.002525e-05
## escolaridadPrimaria o menor 6.090243e-06 1.747328e-05
## compromiso_biopsicosocialModerate 6.652355e-05 3.023312e-05
## compromiso_biopsicosocialSevere 7.483732e-05 4.217519e-05
## tipo_programaEM 1.505889e-05 7.935430e-06
## estatus_ocupacional2 -2.983547e-06 -3.903963e-06
## estatus_ocupacional3 -1.724002e-06 2.505712e-06
## freq_cons2 4.763068e-03 3.306003e-03
## freq_cons3 3.306003e-03 4.092714e-03
## freq_cons4 3.297260e-03 3.298016e-03
## freq_cons5 3.282145e-03 3.289658e-03
## freq_cons6 3.276894e-03 3.278901e-03
## edad_al_ing 2.274642e-07 2.417301e-07
## terap_disTerapeutic discharge:strata(event)event=2 4.527118e-05 6.231351e-05
## terap_disTerapeutic discharge:strata(event)event=3 7.151911e-05 3.673818e-05
## freq_cons4 freq_cons5
## terap_disTerapeutic discharge 8.162247e-07 1.076952e-07
## strata(event)event=2 4.084726e-05 3.760339e-05
## strata(event)event=3 1.766349e-05 2.207674e-05
## sexF 5.439435e-05 5.785364e-05
## edad_inicio -2.278396e-06 -1.883904e-06
## es_conyugalSeparated 1.095788e-06 -3.855400e-06
## es_conyugalSingle -1.216879e-05 -1.565657e-05
## es_conyugalWidower 1.469927e-05 2.619846e-05
## susCocaine 1.425518e-05 1.118589e-05
## susMarijuana 7.668309e-06 -1.262214e-05
## susOther 6.738171e-05 5.404988e-05
## susCocaine paste 3.469273e-05 1.327864e-05
## escolaridadSecundaria o menor 4.389373e-06 1.082143e-05
## escolaridadPrimaria o menor 1.709995e-05 2.644808e-05
## compromiso_biopsicosocialModerate -5.490466e-05 -7.736534e-05
## compromiso_biopsicosocialSevere -5.644985e-05 -1.052246e-04
## tipo_programaEM -4.476405e-06 -1.134775e-05
## estatus_ocupacional2 -1.929985e-06 2.190934e-05
## estatus_ocupacional3 -2.031447e-07 7.908139e-06
## freq_cons2 3.297260e-03 3.282145e-03
## freq_cons3 3.298016e-03 3.289658e-03
## freq_cons4 3.495378e-03 3.313884e-03
## freq_cons5 3.313884e-03 3.612032e-03
## freq_cons6 3.306062e-03 3.329085e-03
## edad_al_ing 4.168662e-07 1.179286e-07
## terap_disTerapeutic discharge:strata(event)event=2 5.188899e-05 5.664377e-05
## terap_disTerapeutic discharge:strata(event)event=3 6.237484e-05 5.893078e-05
## freq_cons6 edad_al_ing
## terap_disTerapeutic discharge 2.315740e-06 -1.136091e-06
## strata(event)event=2 3.510156e-05 -1.144855e-06
## strata(event)event=3 2.188013e-05 -1.764260e-06
## sexF 6.563692e-05 1.192243e-06
## edad_inicio -1.605351e-06 -3.970343e-07
## es_conyugalSeparated -7.369282e-06 -2.190113e-06
## es_conyugalSingle -1.839533e-05 3.570184e-06
## es_conyugalWidower 1.361255e-05 -5.011852e-06
## susCocaine 7.976071e-06 4.539767e-06
## susMarijuana -5.733987e-05 6.135423e-06
## susOther -2.024938e-05 1.872541e-06
## susCocaine paste -1.263442e-05 4.513920e-06
## escolaridadSecundaria o menor 4.751026e-06 2.024848e-07
## escolaridadPrimaria o menor 1.544850e-05 -9.020499e-07
## compromiso_biopsicosocialModerate -7.402290e-05 -2.694886e-07
## compromiso_biopsicosocialSevere -1.316737e-04 -5.482559e-07
## tipo_programaEM -1.803222e-05 4.057912e-07
## estatus_ocupacional2 3.644798e-05 -7.240217e-07
## estatus_ocupacional3 5.102790e-06 -5.378214e-07
## freq_cons2 3.276894e-03 2.274642e-07
## freq_cons3 3.278901e-03 2.417301e-07
## freq_cons4 3.306062e-03 4.168662e-07
## freq_cons5 3.329085e-03 1.179286e-07
## freq_cons6 3.437826e-03 -5.682143e-07
## edad_al_ing -5.682143e-07 6.811296e-07
## terap_disTerapeutic discharge:strata(event)event=2 5.343714e-05 3.048953e-07
## terap_disTerapeutic discharge:strata(event)event=3 4.009974e-05 1.094936e-08
## terap_disTerapeutic discharge:strata(event)event=2
## terap_disTerapeutic discharge -3.692285e-04
## strata(event)event=2 -3.759742e-04
## strata(event)event=3 -7.281422e-05
## sexF 1.152560e-05
## edad_inicio -8.122709e-08
## es_conyugalSeparated 1.116438e-06
## es_conyugalSingle -1.100482e-05
## es_conyugalWidower -9.236578e-08
## susCocaine -1.648251e-05
## susMarijuana 3.022782e-06
## susOther 1.034930e-05
## susCocaine paste -2.932575e-06
## escolaridadSecundaria o menor 1.030224e-05
## escolaridadPrimaria o menor 4.016063e-06
## compromiso_biopsicosocialModerate -7.773101e-06
## compromiso_biopsicosocialSevere 3.314433e-06
## tipo_programaEM -2.963110e-06
## estatus_ocupacional2 7.253046e-06
## estatus_ocupacional3 2.708434e-06
## freq_cons2 4.527118e-05
## freq_cons3 6.231351e-05
## freq_cons4 5.188899e-05
## freq_cons5 5.664377e-05
## freq_cons6 5.343714e-05
## edad_al_ing 3.048953e-07
## terap_disTerapeutic discharge:strata(event)event=2 1.807665e-03
## terap_disTerapeutic discharge:strata(event)event=3 3.811079e-04
## terap_disTerapeutic discharge:strata(event)event=3
## terap_disTerapeutic discharge -4.055398e-04
## strata(event)event=2 -7.978350e-05
## strata(event)event=3 -1.119579e-03
## sexF 7.050478e-06
## edad_inicio 2.616813e-06
## es_conyugalSeparated -8.200319e-06
## es_conyugalSingle -4.054004e-05
## es_conyugalWidower -2.028312e-05
## susCocaine -1.222999e-05
## susMarijuana 2.243579e-05
## susOther 8.812404e-05
## susCocaine paste -8.704332e-07
## escolaridadSecundaria o menor -5.809521e-05
## escolaridadPrimaria o menor -6.611391e-05
## compromiso_biopsicosocialModerate -1.836635e-05
## compromiso_biopsicosocialSevere -1.440716e-06
## tipo_programaEM -4.358711e-07
## estatus_ocupacional2 -1.047178e-05
## estatus_ocupacional3 -2.543446e-05
## freq_cons2 7.151911e-05
## freq_cons3 3.673818e-05
## freq_cons4 6.237484e-05
## freq_cons5 5.893078e-05
## freq_cons6 4.009974e-05
## edad_al_ing 1.094936e-08
## terap_disTerapeutic discharge:strata(event)event=2 3.811079e-04
## terap_disTerapeutic discharge:strata(event)event=3 5.464903e-03
##
## Generalized concordance probability: Estimates may be biased!
## concordance prob. lower 0.95
## terap_disTerapeutic discharge 0.4401 0.4306
## strata(event)event=2 0.6773 0.6688
## strata(event)event=3 0.7484 0.7357
## sexF 0.5488 0.5393
## edad_inicio 0.4970 0.4962
## es_conyugalSeparated 0.5006 0.4885
## es_conyugalSingle 0.4928 0.4849
## es_conyugalWidower 0.4730 0.4372
## susCocaine 0.5433 0.5324
## susMarijuana 0.4618 0.4450
## susOther 0.4895 0.4607
## susCocaine paste 0.5791 0.5700
## escolaridadSecundaria o menor 0.4773 0.4682
## escolaridadPrimaria o menor 0.4326 0.4221
## compromiso_biopsicosocialModerate 0.5165 0.5024
## compromiso_biopsicosocialSevere 0.5655 0.5505
## tipo_programaEM 0.5625 0.5507
## estatus_ocupacional2 0.4763 0.4682
## estatus_ocupacional3 0.4900 0.4804
## freq_cons2 0.5123 0.4785
## freq_cons3 0.5201 0.4888
## freq_cons4 0.5274 0.4984
## freq_cons5 0.5296 0.5002
## freq_cons6 0.5337 0.5050
## edad_al_ing 0.4981 0.4977
## terap_disTerapeutic discharge:strata(event)event=2 0.5001 0.4793
## terap_disTerapeutic discharge:strata(event)event=3 0.5150 0.4788
## upper 0.95
## terap_disTerapeutic discharge 0.4495
## strata(event)event=2 0.6857
## strata(event)event=3 0.7607
## sexF 0.5583
## edad_inicio 0.4978
## es_conyugalSeparated 0.5126
## es_conyugalSingle 0.5007
## es_conyugalWidower 0.5090
## susCocaine 0.5541
## susMarijuana 0.4788
## susOther 0.5183
## susCocaine paste 0.5881
## escolaridadSecundaria o menor 0.4865
## escolaridadPrimaria o menor 0.4431
## compromiso_biopsicosocialModerate 0.5306
## compromiso_biopsicosocialSevere 0.5803
## tipo_programaEM 0.5742
## estatus_ocupacional2 0.4843
## estatus_ocupacional3 0.4996
## freq_cons2 0.5460
## freq_cons3 0.5513
## freq_cons4 0.5561
## freq_cons5 0.5588
## freq_cons6 0.5621
## edad_al_ing 0.4985
## terap_disTerapeutic discharge:strata(event)event=2 0.5209
## terap_disTerapeutic discharge:strata(event)event=3 0.5510# res_tt_3 <- cbind.data.frame(Avg_HR=round(exp(pwp_tt_imp3$coeff),2),
# Lo_ci95=round(exp(confint(pwp_tt_imp3))[,1],2),
# Up_ci95=round(exp(confint(pwp_tt_imp3))[,2],2),
# p=round(summary(pwp_tt_imp3)$prob,4))%>%
# data.table::data.table(keep.rownames=T)
#
# conc_tt_3 <- cbind.data.frame(conc_prob=concord(pwp_tt_imp3)[,1],
# lo_ci95=concord(pwp_tt_imp3)[,2],
# up_ci95=concord(pwp_tt_imp3)[,3],
# conc_p=summary(pwp_tt_imp3, print = FALSE)$prob)%>%
# data.table::data.table(keep.rownames=T)
res_tt_3_cl <- cbind.data.frame(Avg_HR=round(exp(pwp_tt_imp3_cl$coeff),2),
Lo_ci95=round(exp(confint(pwp_tt_imp3_cl))[,1],2),
Up_ci95=round(exp(confint(pwp_tt_imp3_cl))[,2],2),
p=round(summary(pwp_tt_imp3_cl)$prob,4))%>%
data.table::data.table(keep.rownames=T)## coxphw(formula = Surv(tstart, tstop, status == 1) ~ terap_dis *
## strata(event) + sex + edad_inicio + es_conyugal + sus + escolaridad +
## compromiso_biopsicosocial + tipo_programa + estatus_ocupacional +
## freq_cons + edad_al_ing + strata(event), data = rfimp2, template = "AHR",
## robust = T, clusterid = rfimp2$id)
##
## Model fitted by weighted estimation (AHR template)
##
## coef se(coef)
## terap_disTerapeutic discharge -0.128015050 0.095033032
## strata(event)event=2 0.682665528 0.025913115
## strata(event)event=3 1.015811000 0.038490998
## sexF 0.327163332 0.126206625
## edad_inicio -0.025895886 0.006396340
## es_conyugalSeparated -0.046509546 0.055393160
## es_conyugalSingle 0.025012151 0.054649028
## es_conyugalWidower -0.133914662 0.090387045
## susCocaine 0.204860831 0.036540999
## susMarijuana -0.169508031 0.065009768
## susOther -0.177320006 0.147024542
## susCocaine paste 0.406167203 0.066385283
## escolaridadSecundaria o menor -0.009229029 0.050827949
## escolaridadPrimaria o menor -0.258738757 0.033612062
## compromiso_biopsicosocialModerate -0.097746100 0.193823385
## compromiso_biopsicosocialSevere -0.011469398 0.207761945
## tipo_programaEM 0.142228180 0.101977260
## estatus_ocupacional2 -0.112443545 0.071745139
## estatus_ocupacional3 -0.115144537 0.089249672
## freq_cons2 -0.021802060 0.092675124
## freq_cons3 0.147515178 0.089320638
## freq_cons4 0.191723670 0.091894381
## freq_cons5 0.140245759 0.083862648
## freq_cons6 0.193367874 0.103020170
## edad_al_ing -0.002377077 0.003293208
## terap_disTerapeutic discharge:strata(event)event=2 -0.016770593 0.095614780
## terap_disTerapeutic discharge:strata(event)event=3 0.004635424 0.112474552
## exp(coef) lower 0.95
## terap_disTerapeutic discharge 0.8798401 0.7303172
## strata(event)event=2 1.9791462 1.8811377
## strata(event)event=3 2.7616021 2.5609289
## sexF 1.3870280 1.0830736
## edad_inicio 0.9744365 0.9622967
## es_conyugalSeparated 0.9545554 0.8563483
## es_conyugalSingle 1.0253276 0.9211817
## es_conyugalWidower 0.8746647 0.7326626
## susCocaine 1.2273542 1.1425262
## susMarijuana 0.8440800 0.7430999
## susOther 0.8375117 0.6278319
## susCocaine paste 1.5010535 1.3179196
## escolaridadSecundaria o menor 0.9908134 0.8968650
## escolaridadPrimaria o menor 0.7720247 0.7228040
## compromiso_biopsicosocialModerate 0.9068791 0.6202498
## compromiso_biopsicosocialSevere 0.9885961 0.6579178
## tipo_programaEM 1.1528397 0.9439863
## estatus_ocupacional2 0.8936478 0.7764202
## estatus_ocupacional3 0.8912373 0.7482107
## freq_cons2 0.9784339 0.8159176
## freq_cons3 1.1589509 0.9728260
## freq_cons4 1.2113357 1.0116817
## freq_cons5 1.1505565 0.9761666
## freq_cons6 1.2133291 0.9914885
## edad_al_ing 0.9976257 0.9912072
## terap_disTerapeutic discharge:strata(event)event=2 0.9833693 0.8153220
## terap_disTerapeutic discharge:strata(event)event=3 1.0046462 0.8058879
## upper 0.95 z
## terap_disTerapeutic discharge 1.0599760 -1.34705846
## strata(event)event=2 2.0822610 26.34440250
## strata(event)event=3 2.9780001 26.39087168
## sexF 1.7762844 2.59228334
## edad_inicio 0.9867295 -4.04854744
## es_conyugalSeparated 1.0640252 -0.83962616
## es_conyugalSingle 1.1412479 0.45768702
## es_conyugalWidower 1.0441892 -1.48156919
## susCocaine 1.3184804 5.60632811
## susMarijuana 0.9587823 -2.60742403
## susOther 1.1172193 -1.20605719
## susCocaine paste 1.7096351 6.11833200
## escolaridadSecundaria o menor 1.0946032 -0.18157391
## escolaridadPrimaria o menor 0.8245971 -7.69779478
## compromiso_biopsicosocialModerate 1.3259653 -0.50430499
## compromiso_biopsicosocialSevere 1.4854779 -0.05520452
## tipo_programaEM 1.4079010 1.39470485
## estatus_ocupacional2 1.0285750 -1.56726361
## estatus_ocupacional3 1.0616047 -1.29013961
## freq_cons2 1.1733206 -0.23525256
## freq_cons3 1.3806859 1.65152401
## freq_cons4 1.4503912 2.08634813
## freq_cons5 1.3561008 1.67232686
## freq_cons6 1.4848054 1.87699045
## edad_al_ing 1.0040858 -0.72181212
## terap_disTerapeutic discharge:strata(event)event=2 1.1860529 -0.17539750
## terap_disTerapeutic discharge:strata(event)event=3 1.2524248 0.04121310
## p
## terap_disTerapeutic discharge 1.779614e-01
## strata(event)event=2 0.000000e+00
## strata(event)event=3 0.000000e+00
## sexF 9.534121e-03
## edad_inicio 5.153649e-05
## es_conyugalSeparated 4.011180e-01
## es_conyugalSingle 6.471773e-01
## es_conyugalWidower 1.384550e-01
## susCocaine 2.066640e-08
## susMarijuana 9.122631e-03
## susOther 2.277954e-01
## susCocaine paste 9.455990e-10
## escolaridadSecundaria o menor 8.559171e-01
## escolaridadPrimaria o menor 1.387779e-14
## compromiso_biopsicosocialModerate 6.140471e-01
## compromiso_biopsicosocialSevere 9.559755e-01
## tipo_programaEM 1.631049e-01
## estatus_ocupacional2 1.170531e-01
## estatus_ocupacional3 1.970022e-01
## freq_cons2 8.140127e-01
## freq_cons3 9.863162e-02
## freq_cons4 3.694710e-02
## freq_cons5 9.445989e-02
## freq_cons6 6.051940e-02
## edad_al_ing 4.704100e-01
## terap_disTerapeutic discharge:strata(event)event=2 8.607673e-01
## terap_disTerapeutic discharge:strata(event)event=3 9.671260e-01
##
## Wald Chi-square = 4404.269 on 27 df p = 0 n = 107665
##
## Covariance-Matrix:
## terap_disTerapeutic discharge
## terap_disTerapeutic discharge 0.0090312771
## strata(event)event=2 0.0013406588
## strata(event)event=3 0.0010303048
## sexF 0.0083878556
## edad_inicio -0.0003441041
## es_conyugalSeparated 0.0030784668
## es_conyugalSingle 0.0039531840
## es_conyugalWidower 0.0035207666
## susCocaine -0.0013795439
## susMarijuana -0.0011637518
## susOther -0.0014925631
## susCocaine paste -0.0011035184
## escolaridadSecundaria o menor 0.0010184930
## escolaridadPrimaria o menor 0.0011469379
## compromiso_biopsicosocialModerate 0.0147587282
## compromiso_biopsicosocialSevere 0.0128121326
## tipo_programaEM -0.0067862940
## estatus_ocupacional2 -0.0053330385
## estatus_ocupacional3 -0.0050841315
## freq_cons2 0.0004091846
## freq_cons3 -0.0006541798
## freq_cons4 0.0022444574
## freq_cons5 -0.0033928112
## freq_cons6 -0.0053312170
## edad_al_ing -0.0001159744
## terap_disTerapeutic discharge:strata(event)event=2 -0.0081227299
## terap_disTerapeutic discharge:strata(event)event=3 -0.0080342106
## strata(event)event=2
## terap_disTerapeutic discharge 1.340659e-03
## strata(event)event=2 6.714895e-04
## strata(event)event=3 3.236091e-04
## sexF 6.508930e-04
## edad_inicio -1.634442e-05
## es_conyugalSeparated 6.026426e-04
## es_conyugalSingle 4.053095e-04
## es_conyugalWidower 5.188089e-04
## susCocaine -2.552018e-04
## susMarijuana 7.931687e-05
## susOther 4.853196e-04
## susCocaine paste -5.919111e-04
## escolaridadSecundaria o menor -1.215184e-04
## escolaridadPrimaria o menor 2.121463e-04
## compromiso_biopsicosocialModerate 2.694733e-03
## compromiso_biopsicosocialSevere 2.709902e-03
## tipo_programaEM -5.980949e-04
## estatus_ocupacional2 -5.522254e-04
## estatus_ocupacional3 -3.359803e-04
## freq_cons2 2.904871e-04
## freq_cons3 3.508658e-05
## freq_cons4 6.183149e-05
## freq_cons5 -5.236140e-04
## freq_cons6 -9.786362e-04
## edad_al_ing -3.642475e-05
## terap_disTerapeutic discharge:strata(event)event=2 -1.554080e-03
## terap_disTerapeutic discharge:strata(event)event=3 -1.200359e-03
## strata(event)event=3
## terap_disTerapeutic discharge 1.030305e-03
## strata(event)event=2 3.236091e-04
## strata(event)event=3 1.481557e-03
## sexF 6.843392e-05
## edad_inicio 1.149542e-05
## es_conyugalSeparated 5.903331e-04
## es_conyugalSingle 1.976969e-04
## es_conyugalWidower 3.589491e-04
## susCocaine -2.403583e-04
## susMarijuana 2.156330e-04
## susOther 8.942658e-04
## susCocaine paste -7.793546e-04
## escolaridadSecundaria o menor -2.587053e-04
## escolaridadPrimaria o menor 2.145437e-04
## compromiso_biopsicosocialModerate 2.428503e-03
## compromiso_biopsicosocialSevere 2.661994e-03
## tipo_programaEM -1.769428e-04
## estatus_ocupacional2 -2.330530e-04
## estatus_ocupacional3 5.955451e-05
## freq_cons2 3.519220e-04
## freq_cons3 8.163873e-05
## freq_cons4 -1.923128e-04
## freq_cons5 -4.540978e-04
## freq_cons6 -9.174312e-04
## edad_al_ing -4.165347e-05
## terap_disTerapeutic discharge:strata(event)event=2 -9.537868e-04
## terap_disTerapeutic discharge:strata(event)event=3 -2.078846e-03
## sexF edad_inicio
## terap_disTerapeutic discharge 8.387856e-03 -3.441041e-04
## strata(event)event=2 6.508930e-04 -1.634442e-05
## strata(event)event=3 6.843392e-05 1.149542e-05
## sexF 1.592811e-02 -7.302799e-04
## edad_inicio -7.302799e-04 4.091317e-05
## es_conyugalSeparated 1.018065e-03 -7.893095e-06
## es_conyugalSingle 6.008572e-03 -2.744016e-04
## es_conyugalWidower 3.585430e-03 -1.540538e-04
## susCocaine -9.329644e-04 2.152087e-05
## susMarijuana -3.380724e-03 1.671799e-04
## susOther -1.008763e-02 5.425976e-04
## susCocaine paste 3.604239e-03 -2.276192e-04
## escolaridadSecundaria o menor 4.422613e-03 -2.343915e-04
## escolaridadPrimaria o menor 5.621135e-04 -1.638922e-05
## compromiso_biopsicosocialModerate 7.285811e-03 -1.702419e-04
## compromiso_biopsicosocialSevere 1.282304e-03 1.461578e-04
## tipo_programaEM -1.238168e-02 5.595200e-04
## estatus_ocupacional2 -8.168661e-03 3.727319e-04
## estatus_ocupacional3 -1.057240e-02 4.979215e-04
## freq_cons2 -1.869110e-03 1.106888e-04
## freq_cons3 -9.349704e-04 3.104248e-05
## freq_cons4 6.619703e-03 -3.403681e-04
## freq_cons5 -2.019883e-03 5.917829e-05
## freq_cons6 -1.871188e-03 1.481227e-05
## edad_al_ing 1.103548e-04 -8.656386e-06
## terap_disTerapeutic discharge:strata(event)event=2 -7.180922e-03 2.878188e-04
## terap_disTerapeutic discharge:strata(event)event=3 -7.249563e-03 2.985120e-04
## es_conyugalSeparated
## terap_disTerapeutic discharge 3.078467e-03
## strata(event)event=2 6.026426e-04
## strata(event)event=3 5.903331e-04
## sexF 1.018065e-03
## edad_inicio -7.893095e-06
## es_conyugalSeparated 3.068402e-03
## es_conyugalSingle 1.172797e-03
## es_conyugalWidower 1.730574e-03
## susCocaine -9.081501e-04
## susMarijuana 5.115033e-04
## susOther 2.361162e-03
## susCocaine paste -2.126223e-03
## escolaridadSecundaria o menor -8.279419e-04
## escolaridadPrimaria o menor 5.726467e-04
## compromiso_biopsicosocialModerate 8.228925e-03
## compromiso_biopsicosocialSevere 8.794986e-03
## tipo_programaEM -1.045800e-03
## estatus_ocupacional2 -1.256688e-03
## estatus_ocupacional3 -2.462252e-04
## freq_cons2 1.025853e-03
## freq_cons3 1.326486e-04
## freq_cons4 -6.552781e-04
## freq_cons5 -1.875274e-03
## freq_cons6 -3.357389e-03
## edad_al_ing -1.277015e-04
## terap_disTerapeutic discharge:strata(event)event=2 -2.832197e-03
## terap_disTerapeutic discharge:strata(event)event=3 -2.710518e-03
## es_conyugalSingle
## terap_disTerapeutic discharge 3.953184e-03
## strata(event)event=2 4.053095e-04
## strata(event)event=3 1.976969e-04
## sexF 6.008572e-03
## edad_inicio -2.744016e-04
## es_conyugalSeparated 1.172797e-03
## es_conyugalSingle 2.986516e-03
## es_conyugalWidower 1.960382e-03
## susCocaine -5.882182e-04
## susMarijuana -1.002998e-03
## susOther -3.154683e-03
## susCocaine paste 8.322957e-04
## escolaridadSecundaria o menor 1.429715e-03
## escolaridadPrimaria o menor 4.478403e-04
## compromiso_biopsicosocialModerate 4.800595e-03
## compromiso_biopsicosocialSevere 2.719450e-03
## tipo_programaEM -4.784345e-03
## estatus_ocupacional2 -3.297255e-03
## estatus_ocupacional3 -3.963628e-03
## freq_cons2 -4.921538e-04
## freq_cons3 -1.774993e-04
## freq_cons4 2.240504e-03
## freq_cons5 -1.323911e-03
## freq_cons6 -1.628777e-03
## edad_al_ing 1.416182e-05
## terap_disTerapeutic discharge:strata(event)event=2 -3.446981e-03
## terap_disTerapeutic discharge:strata(event)event=3 -3.464166e-03
## es_conyugalWidower
## terap_disTerapeutic discharge 3.520767e-03
## strata(event)event=2 5.188089e-04
## strata(event)event=3 3.589491e-04
## sexF 3.585430e-03
## edad_inicio -1.540538e-04
## es_conyugalSeparated 1.730574e-03
## es_conyugalSingle 1.960382e-03
## es_conyugalWidower 8.169818e-03
## susCocaine -6.982523e-04
## susMarijuana -2.170800e-04
## susOther -7.838777e-04
## susCocaine paste -5.161845e-04
## escolaridadSecundaria o menor 3.503106e-04
## escolaridadPrimaria o menor 3.384432e-04
## compromiso_biopsicosocialModerate 6.347715e-03
## compromiso_biopsicosocialSevere 5.474113e-03
## tipo_programaEM -2.982326e-03
## estatus_ocupacional2 -2.384182e-03
## estatus_ocupacional3 -2.314829e-03
## freq_cons2 1.848328e-04
## freq_cons3 1.111795e-05
## freq_cons4 9.337017e-04
## freq_cons5 -1.530600e-03
## freq_cons6 -2.421920e-03
## edad_al_ing -6.290542e-05
## terap_disTerapeutic discharge:strata(event)event=2 -3.132971e-03
## terap_disTerapeutic discharge:strata(event)event=3 -3.051329e-03
## susCocaine susMarijuana
## terap_disTerapeutic discharge -1.379544e-03 -1.163752e-03
## strata(event)event=2 -2.552018e-04 7.931687e-05
## strata(event)event=3 -2.403583e-04 2.156330e-04
## sexF -9.329644e-04 -3.380724e-03
## edad_inicio 2.152087e-05 1.671799e-04
## es_conyugalSeparated -9.081501e-04 5.115033e-04
## es_conyugalSingle -5.882182e-04 -1.002998e-03
## es_conyugalWidower -6.982523e-04 -2.170800e-04
## susCocaine 1.335245e-03 1.939147e-04
## susMarijuana 1.939147e-04 4.226270e-03
## susOther -4.663417e-04 3.442004e-03
## susCocaine paste 1.189060e-03 -1.153218e-03
## escolaridadSecundaria o menor 2.934464e-04 -1.071725e-03
## escolaridadPrimaria o menor -1.553067e-04 1.635976e-04
## compromiso_biopsicosocialModerate -3.711626e-03 3.371353e-04
## compromiso_biopsicosocialSevere -3.803105e-03 1.990800e-03
## tipo_programaEM 7.678496e-04 2.587320e-03
## estatus_ocupacional2 7.972962e-04 1.586639e-03
## estatus_ocupacional3 4.314286e-04 2.297949e-03
## freq_cons2 -3.449747e-04 7.058124e-04
## freq_cons3 -1.413753e-04 1.480249e-03
## freq_cons4 1.367601e-04 -1.680772e-03
## freq_cons5 8.754879e-04 -4.061013e-05
## freq_cons6 1.526155e-03 -5.711483e-04
## edad_al_ing 5.818400e-05 -6.117209e-05
## terap_disTerapeutic discharge:strata(event)event=2 1.259479e-03 9.529835e-04
## terap_disTerapeutic discharge:strata(event)event=3 1.184922e-03 1.027963e-03
## susOther
## terap_disTerapeutic discharge -0.0014925631
## strata(event)event=2 0.0004853196
## strata(event)event=3 0.0008942658
## sexF -0.0100876340
## edad_inicio 0.0005425976
## es_conyugalSeparated 0.0023611623
## es_conyugalSingle -0.0031546830
## es_conyugalWidower -0.0007838777
## susCocaine -0.0004663417
## susMarijuana 0.0034420040
## susOther 0.0216162159
## susCocaine paste -0.0058918154
## escolaridadSecundaria o menor -0.0045610566
## escolaridadPrimaria o menor 0.0005766571
## compromiso_biopsicosocialModerate 0.0079193155
## compromiso_biopsicosocialSevere 0.0135018321
## tipo_programaEM 0.0075212046
## estatus_ocupacional2 0.0042903443
## estatus_ocupacional3 0.0074838781
## freq_cons2 0.0030675099
## freq_cons3 0.0010339354
## freq_cons4 -0.0059680850
## freq_cons5 -0.0013298906
## freq_cons6 -0.0039405745
## edad_al_ing -0.0002781317
## terap_disTerapeutic discharge:strata(event)event=2 0.0009554511
## terap_disTerapeutic discharge:strata(event)event=3 0.0012139044
## susCocaine paste
## terap_disTerapeutic discharge -0.0011035184
## strata(event)event=2 -0.0005919111
## strata(event)event=3 -0.0007793546
## sexF 0.0036042385
## edad_inicio -0.0002276192
## es_conyugalSeparated -0.0021262230
## es_conyugalSingle 0.0008322957
## es_conyugalWidower -0.0005161845
## susCocaine 0.0011890598
## susMarijuana -0.0011532180
## susOther -0.0058918154
## susCocaine paste 0.0044070058
## escolaridadSecundaria o menor 0.0024262051
## escolaridadPrimaria o menor -0.0004390894
## compromiso_biopsicosocialModerate -0.0080270918
## compromiso_biopsicosocialSevere -0.0107232158
## tipo_programaEM -0.0025456493
## estatus_ocupacional2 -0.0009571073
## estatus_ocupacional3 -0.0030155958
## freq_cons2 -0.0017911187
## freq_cons3 -0.0002353937
## freq_cons4 0.0029014358
## freq_cons5 0.0015901266
## freq_cons6 0.0035171343
## edad_al_ing 0.0001967844
## terap_disTerapeutic discharge:strata(event)event=2 0.0012055836
## terap_disTerapeutic discharge:strata(event)event=3 0.0010372007
## escolaridadSecundaria o menor
## terap_disTerapeutic discharge 0.0010184930
## strata(event)event=2 -0.0001215184
## strata(event)event=3 -0.0002587053
## sexF 0.0044226133
## edad_inicio -0.0002343915
## es_conyugalSeparated -0.0008279419
## es_conyugalSingle 0.0014297149
## es_conyugalWidower 0.0003503106
## susCocaine 0.0002934464
## susMarijuana -0.0010717250
## susOther -0.0045610566
## susCocaine paste 0.0024262051
## escolaridadSecundaria o menor 0.0025834804
## escolaridadPrimaria o menor 0.0003889888
## compromiso_biopsicosocialModerate -0.0025418860
## compromiso_biopsicosocialSevere -0.0049061872
## tipo_programaEM -0.0032680283
## estatus_ocupacional2 -0.0019731441
## estatus_ocupacional3 -0.0033162670
## freq_cons2 -0.0012385138
## freq_cons3 -0.0001101632
## freq_cons4 0.0025492751
## freq_cons5 0.0004003864
## freq_cons6 0.0013126567
## edad_al_ing 0.0001068419
## terap_disTerapeutic discharge:strata(event)event=2 -0.0007532966
## terap_disTerapeutic discharge:strata(event)event=3 -0.0008888952
## escolaridadPrimaria o menor
## terap_disTerapeutic discharge 1.146938e-03
## strata(event)event=2 2.121463e-04
## strata(event)event=3 2.145437e-04
## sexF 5.621135e-04
## edad_inicio -1.638922e-05
## es_conyugalSeparated 5.726467e-04
## es_conyugalSingle 4.478403e-04
## es_conyugalWidower 3.384432e-04
## susCocaine -1.553067e-04
## susMarijuana 1.635976e-04
## susOther 5.766571e-04
## susCocaine paste -4.390894e-04
## escolaridadSecundaria o menor 3.889888e-04
## escolaridadPrimaria o menor 1.129771e-03
## compromiso_biopsicosocialModerate 2.367716e-03
## compromiso_biopsicosocialSevere 2.371812e-03
## tipo_programaEM -4.911461e-04
## estatus_ocupacional2 -4.904836e-04
## estatus_ocupacional3 -3.577243e-04
## freq_cons2 2.047625e-04
## freq_cons3 2.764856e-04
## freq_cons4 3.010520e-05
## freq_cons5 -4.669340e-04
## freq_cons6 -8.496601e-04
## edad_al_ing -2.977983e-05
## terap_disTerapeutic discharge:strata(event)event=2 -1.010814e-03
## terap_disTerapeutic discharge:strata(event)event=3 -1.042994e-03
## compromiso_biopsicosocialModerate
## terap_disTerapeutic discharge 0.0147587282
## strata(event)event=2 0.0026947334
## strata(event)event=3 0.0024285033
## sexF 0.0072858106
## edad_inicio -0.0001702419
## es_conyugalSeparated 0.0082289251
## es_conyugalSingle 0.0048005950
## es_conyugalWidower 0.0063477154
## susCocaine -0.0037116261
## susMarijuana 0.0003371353
## susOther 0.0079193155
## susCocaine paste -0.0080270918
## escolaridadSecundaria o menor -0.0025418860
## escolaridadPrimaria o menor 0.0023677156
## compromiso_biopsicosocialModerate 0.0375675044
## compromiso_biopsicosocialSevere 0.0386779164
## tipo_programaEM -0.0066628611
## estatus_ocupacional2 -0.0067922808
## estatus_ocupacional3 -0.0030668438
## freq_cons2 0.0036481838
## freq_cons3 -0.0006511664
## freq_cons4 -0.0013056612
## freq_cons5 -0.0082089372
## freq_cons6 -0.0144046035
## edad_al_ing -0.0004803714
## terap_disTerapeutic discharge:strata(event)event=2 -0.0134750975
## terap_disTerapeutic discharge:strata(event)event=3 -0.0130404790
## compromiso_biopsicosocialSevere
## terap_disTerapeutic discharge 0.0128121326
## strata(event)event=2 0.0027099020
## strata(event)event=3 0.0026619944
## sexF 0.0012823037
## edad_inicio 0.0001461578
## es_conyugalSeparated 0.0087949855
## es_conyugalSingle 0.0027194503
## es_conyugalWidower 0.0054741127
## susCocaine -0.0038031052
## susMarijuana 0.0019907997
## susOther 0.0135018321
## susCocaine paste -0.0107232158
## escolaridadSecundaria o menor -0.0049061872
## escolaridadPrimaria o menor 0.0023718120
## compromiso_biopsicosocialModerate 0.0386779164
## compromiso_biopsicosocialSevere 0.0431650257
## tipo_programaEM -0.0022178976
## estatus_ocupacional2 -0.0038131877
## estatus_ocupacional3 0.0013007679
## freq_cons2 0.0050175711
## freq_cons3 -0.0002561156
## freq_cons4 -0.0044772613
## freq_cons5 -0.0083051054
## freq_cons6 -0.0154174830
## edad_al_ing -0.0005911978
## terap_disTerapeutic discharge:strata(event)event=2 -0.0119043240
## terap_disTerapeutic discharge:strata(event)event=3 -0.0113789838
## tipo_programaEM
## terap_disTerapeutic discharge -6.786294e-03
## strata(event)event=2 -5.980949e-04
## strata(event)event=3 -1.769428e-04
## sexF -1.238168e-02
## edad_inicio 5.595200e-04
## es_conyugalSeparated -1.045800e-03
## es_conyugalSingle -4.784345e-03
## es_conyugalWidower -2.982326e-03
## susCocaine 7.678496e-04
## susMarijuana 2.587320e-03
## susOther 7.521205e-03
## susCocaine paste -2.545649e-03
## escolaridadSecundaria o menor -3.268028e-03
## escolaridadPrimaria o menor -4.911461e-04
## compromiso_biopsicosocialModerate -6.662861e-03
## compromiso_biopsicosocialSevere -2.217898e-03
## tipo_programaEM 1.039936e-02
## estatus_ocupacional2 6.432232e-03
## estatus_ocupacional3 8.064772e-03
## freq_cons2 1.361079e-03
## freq_cons3 7.401452e-04
## freq_cons4 -4.959471e-03
## freq_cons5 1.833011e-03
## freq_cons6 1.861259e-03
## edad_al_ing -7.226479e-05
## terap_disTerapeutic discharge:strata(event)event=2 5.825821e-03
## terap_disTerapeutic discharge:strata(event)event=3 5.865837e-03
## estatus_ocupacional2
## terap_disTerapeutic discharge -5.333038e-03
## strata(event)event=2 -5.522254e-04
## strata(event)event=3 -2.330530e-04
## sexF -8.168661e-03
## edad_inicio 3.727319e-04
## es_conyugalSeparated -1.256688e-03
## es_conyugalSingle -3.297255e-03
## es_conyugalWidower -2.384182e-03
## susCocaine 7.972962e-04
## susMarijuana 1.586639e-03
## susOther 4.290344e-03
## susCocaine paste -9.571073e-04
## escolaridadSecundaria o menor -1.973144e-03
## escolaridadPrimaria o menor -4.904836e-04
## compromiso_biopsicosocialModerate -6.792281e-03
## compromiso_biopsicosocialSevere -3.813188e-03
## tipo_programaEM 6.432232e-03
## estatus_ocupacional2 5.147365e-03
## estatus_ocupacional3 5.577400e-03
## freq_cons2 5.678717e-04
## freq_cons3 3.918935e-04
## freq_cons4 -3.162025e-03
## freq_cons5 1.732494e-03
## freq_cons6 2.296175e-03
## edad_al_ing -8.647733e-06
## terap_disTerapeutic discharge:strata(event)event=2 4.656619e-03
## terap_disTerapeutic discharge:strata(event)event=3 4.607783e-03
## estatus_ocupacional3
## terap_disTerapeutic discharge -5.084131e-03
## strata(event)event=2 -3.359803e-04
## strata(event)event=3 5.955451e-05
## sexF -1.057240e-02
## edad_inicio 4.979215e-04
## es_conyugalSeparated -2.462252e-04
## es_conyugalSingle -3.963628e-03
## es_conyugalWidower -2.314829e-03
## susCocaine 4.314286e-04
## susMarijuana 2.297949e-03
## susOther 7.483878e-03
## susCocaine paste -3.015596e-03
## escolaridadSecundaria o menor -3.316267e-03
## escolaridadPrimaria o menor -3.577243e-04
## compromiso_biopsicosocialModerate -3.066844e-03
## compromiso_biopsicosocialSevere 1.300768e-03
## tipo_programaEM 8.064772e-03
## estatus_ocupacional2 5.577400e-03
## estatus_ocupacional3 7.965504e-03
## freq_cons2 1.544789e-03
## freq_cons3 5.466045e-04
## freq_cons4 -4.694413e-03
## freq_cons5 1.007269e-03
## freq_cons6 5.650858e-04
## edad_al_ing -1.041282e-04
## terap_disTerapeutic discharge:strata(event)event=2 4.328720e-03
## terap_disTerapeutic discharge:strata(event)event=3 4.329787e-03
## freq_cons2 freq_cons3
## terap_disTerapeutic discharge 4.091846e-04 -6.541798e-04
## strata(event)event=2 2.904871e-04 3.508658e-05
## strata(event)event=3 3.519220e-04 8.163873e-05
## sexF -1.869110e-03 -9.349704e-04
## edad_inicio 1.106888e-04 3.104248e-05
## es_conyugalSeparated 1.025853e-03 1.326486e-04
## es_conyugalSingle -4.921538e-04 -1.774993e-04
## es_conyugalWidower 1.848328e-04 1.111795e-05
## susCocaine -3.449747e-04 -1.413753e-04
## susMarijuana 7.058124e-04 1.480249e-03
## susOther 3.067510e-03 1.033935e-03
## susCocaine paste -1.791119e-03 -2.353937e-04
## escolaridadSecundaria o menor -1.238514e-03 -1.101632e-04
## escolaridadPrimaria o menor 2.047625e-04 2.764856e-04
## compromiso_biopsicosocialModerate 3.648184e-03 -6.511664e-04
## compromiso_biopsicosocialSevere 5.017571e-03 -2.561156e-04
## tipo_programaEM 1.361079e-03 7.401452e-04
## estatus_ocupacional2 5.678717e-04 3.918935e-04
## estatus_ocupacional3 1.544789e-03 5.466045e-04
## freq_cons2 8.588679e-03 4.759996e-03
## freq_cons3 4.759996e-03 7.978176e-03
## freq_cons4 3.211571e-03 4.279255e-03
## freq_cons5 3.954201e-03 4.718512e-03
## freq_cons6 3.058869e-03 4.675143e-03
## edad_al_ing -8.491421e-05 -1.842892e-05
## terap_disTerapeutic discharge:strata(event)event=2 -4.203733e-04 6.822244e-04
## terap_disTerapeutic discharge:strata(event)event=3 -3.605225e-04 5.940730e-04
## freq_cons4 freq_cons5
## terap_disTerapeutic discharge 2.244457e-03 -3.392811e-03
## strata(event)event=2 6.183149e-05 -5.236140e-04
## strata(event)event=3 -1.923128e-04 -4.540978e-04
## sexF 6.619703e-03 -2.019883e-03
## edad_inicio -3.403681e-04 5.917829e-05
## es_conyugalSeparated -6.552781e-04 -1.875274e-03
## es_conyugalSingle 2.240504e-03 -1.323911e-03
## es_conyugalWidower 9.337017e-04 -1.530600e-03
## susCocaine 1.367601e-04 8.754879e-04
## susMarijuana -1.680772e-03 -4.061013e-05
## susOther -5.968085e-03 -1.329891e-03
## susCocaine paste 2.901436e-03 1.590127e-03
## escolaridadSecundaria o menor 2.549275e-03 4.003864e-04
## escolaridadPrimaria o menor 3.010520e-05 -4.669340e-04
## compromiso_biopsicosocialModerate -1.305661e-03 -8.208937e-03
## compromiso_biopsicosocialSevere -4.477261e-03 -8.305105e-03
## tipo_programaEM -4.959471e-03 1.833011e-03
## estatus_ocupacional2 -3.162025e-03 1.732494e-03
## estatus_ocupacional3 -4.694413e-03 1.007269e-03
## freq_cons2 3.211571e-03 3.954201e-03
## freq_cons3 4.279255e-03 4.718512e-03
## freq_cons4 8.444577e-03 4.729672e-03
## freq_cons5 4.729672e-03 7.032944e-03
## freq_cons6 5.624930e-03 7.856219e-03
## edad_al_ing 1.199733e-04 1.012032e-04
## terap_disTerapeutic discharge:strata(event)event=2 -1.762977e-03 3.157569e-03
## terap_disTerapeutic discharge:strata(event)event=3 -1.884867e-03 3.008490e-03
## freq_cons6 edad_al_ing
## terap_disTerapeutic discharge -5.331217e-03 -1.159744e-04
## strata(event)event=2 -9.786362e-04 -3.642475e-05
## strata(event)event=3 -9.174312e-04 -4.165347e-05
## sexF -1.871188e-03 1.103548e-04
## edad_inicio 1.481227e-05 -8.656386e-06
## es_conyugalSeparated -3.357389e-03 -1.277015e-04
## es_conyugalSingle -1.628777e-03 1.416182e-05
## es_conyugalWidower -2.421920e-03 -6.290542e-05
## susCocaine 1.526155e-03 5.818400e-05
## susMarijuana -5.711483e-04 -6.117209e-05
## susOther -3.940575e-03 -2.781317e-04
## susCocaine paste 3.517134e-03 1.967844e-04
## escolaridadSecundaria o menor 1.312657e-03 1.068419e-04
## escolaridadPrimaria o menor -8.496601e-04 -2.977983e-05
## compromiso_biopsicosocialModerate -1.440460e-02 -4.803714e-04
## compromiso_biopsicosocialSevere -1.541748e-02 -5.911978e-04
## tipo_programaEM 1.861259e-03 -7.226479e-05
## estatus_ocupacional2 2.296175e-03 -8.647733e-06
## estatus_ocupacional3 5.650858e-04 -1.041282e-04
## freq_cons2 3.058869e-03 -8.491421e-05
## freq_cons3 4.675143e-03 -1.842892e-05
## freq_cons4 5.624930e-03 1.199733e-04
## freq_cons5 7.856219e-03 1.012032e-04
## freq_cons6 1.061316e-02 2.072086e-04
## edad_al_ing 2.072086e-04 1.084522e-05
## terap_disTerapeutic discharge:strata(event)event=2 4.959676e-03 1.110583e-04
## terap_disTerapeutic discharge:strata(event)event=3 4.713263e-03 1.023796e-04
## terap_disTerapeutic discharge:strata(event)event=2
## terap_disTerapeutic discharge -0.0081227299
## strata(event)event=2 -0.0015540804
## strata(event)event=3 -0.0009537868
## sexF -0.0071809219
## edad_inicio 0.0002878188
## es_conyugalSeparated -0.0028321975
## es_conyugalSingle -0.0034469812
## es_conyugalWidower -0.0031329708
## susCocaine 0.0012594787
## susMarijuana 0.0009529835
## susOther 0.0009554511
## susCocaine paste 0.0012055836
## escolaridadSecundaria o menor -0.0007532966
## escolaridadPrimaria o menor -0.0010108139
## compromiso_biopsicosocialModerate -0.0134750975
## compromiso_biopsicosocialSevere -0.0119043240
## tipo_programaEM 0.0058258215
## estatus_ocupacional2 0.0046566187
## estatus_ocupacional3 0.0043287201
## freq_cons2 -0.0004203733
## freq_cons3 0.0006822244
## freq_cons4 -0.0017629767
## freq_cons5 0.0031575695
## freq_cons6 0.0049596760
## edad_al_ing 0.0001110583
## terap_disTerapeutic discharge:strata(event)event=2 0.0091421862
## terap_disTerapeutic discharge:strata(event)event=3 0.0072312395
## terap_disTerapeutic discharge:strata(event)event=3
## terap_disTerapeutic discharge -0.0080342106
## strata(event)event=2 -0.0012003586
## strata(event)event=3 -0.0020788461
## sexF -0.0072495630
## edad_inicio 0.0002985120
## es_conyugalSeparated -0.0027105178
## es_conyugalSingle -0.0034641659
## es_conyugalWidower -0.0030513286
## susCocaine 0.0011849218
## susMarijuana 0.0010279625
## susOther 0.0012139044
## susCocaine paste 0.0010372007
## escolaridadSecundaria o menor -0.0008888952
## escolaridadPrimaria o menor -0.0010429938
## compromiso_biopsicosocialModerate -0.0130404790
## compromiso_biopsicosocialSevere -0.0113789838
## tipo_programaEM 0.0058658370
## estatus_ocupacional2 0.0046077826
## estatus_ocupacional3 0.0043297870
## freq_cons2 -0.0003605225
## freq_cons3 0.0005940730
## freq_cons4 -0.0018848671
## freq_cons5 0.0030084904
## freq_cons6 0.0047132629
## edad_al_ing 0.0001023796
## terap_disTerapeutic discharge:strata(event)event=2 0.0072312395
## terap_disTerapeutic discharge:strata(event)event=3 0.0126505249
##
## Generalized concordance probability:
## concordance prob. lower 0.95
## terap_disTerapeutic discharge 0.4680 0.4221
## strata(event)event=2 0.6643 0.6529
## strata(event)event=3 0.7342 0.7192
## sexF 0.5811 0.5199
## edad_inicio 0.4935 0.4904
## es_conyugalSeparated 0.4884 0.4613
## es_conyugalSingle 0.5063 0.4795
## es_conyugalWidower 0.4666 0.4229
## susCocaine 0.5510 0.5333
## susMarijuana 0.4577 0.4263
## susOther 0.4558 0.3857
## susCocaine paste 0.6002 0.5686
## escolaridadSecundaria o menor 0.4977 0.4728
## escolaridadPrimaria o menor 0.4357 0.4196
## compromiso_biopsicosocialModerate 0.4756 0.3828
## compromiso_biopsicosocialSevere 0.4971 0.3968
## tipo_programaEM 0.5355 0.4856
## estatus_ocupacional2 0.4719 0.4371
## estatus_ocupacional3 0.4712 0.4280
## freq_cons2 0.4945 0.4493
## freq_cons3 0.5368 0.4931
## freq_cons4 0.5478 0.5029
## freq_cons5 0.5350 0.4940
## freq_cons6 0.5482 0.4979
## edad_al_ing 0.4994 0.4978
## terap_disTerapeutic discharge:strata(event)event=2 0.4958 0.4491
## terap_disTerapeutic discharge:strata(event)event=3 0.5012 0.4463
## upper 0.95
## terap_disTerapeutic discharge 0.5146
## strata(event)event=2 0.6756
## strata(event)event=3 0.7486
## sexF 0.6398
## edad_inicio 0.4967
## es_conyugalSeparated 0.5155
## es_conyugalSingle 0.5330
## es_conyugalWidower 0.5108
## susCocaine 0.5687
## susMarijuana 0.4895
## susOther 0.5277
## susCocaine paste 0.6309
## escolaridadSecundaria o menor 0.5226
## escolaridadPrimaria o menor 0.4519
## compromiso_biopsicosocialModerate 0.5701
## compromiso_biopsicosocialSevere 0.5977
## tipo_programaEM 0.5847
## estatus_ocupacional2 0.5070
## estatus_ocupacional3 0.5149
## freq_cons2 0.5399
## freq_cons3 0.5800
## freq_cons4 0.5919
## freq_cons5 0.5756
## freq_cons6 0.5976
## edad_al_ing 0.5010
## terap_disTerapeutic discharge:strata(event)event=2 0.5426
## terap_disTerapeutic discharge:strata(event)event=3 0.5560conc_tt_3_cl <- cbind.data.frame(conc_prob=concord(pwp_tt_imp3_cl)[,1],
lo_ci95=concord(pwp_tt_imp3_cl)[,2],
up_ci95=concord(pwp_tt_imp3_cl)[,3],
conc_p=summary(pwp_tt_imp3_cl, print = FALSE)$prob)%>%
data.table::data.table(keep.rownames=T)
res_tt_2_orig <- cbind.data.frame(HR=round(exp(coef(pwp_tt_imp_2)),2),
Lo_CI95=round(exp(confint(pwp_tt_imp_2)[,1]),2),
Up_CI95=round(exp(confint(pwp_tt_imp_2)[,2]),2))%>%
data.table::data.table(keep.rownames=T)options(knitr.kable.NA = '')
res_gt_2_cl %>%
dplyr::left_join(res_gt_2_orig, by="rn") %>%
dplyr::left_join(res_gt_3_cl, by="rn") %>%
dplyr::left_join(conc_gt_3_cl, by="rn") %>%
#dplyr::bind_cols(res_gt_2_orig,res_gt_2,res_gt_3,conc_gt_3) %>%
knitr::kable("html") %>%
kableExtra::kable_classic(bootstrap_options = c("striped", "hover"),font_size = 12) %>%
kableExtra::add_header_above( c(" ", "PWP HR Var. Robusta" = 4, "PWP Original" = 3, "PWP Weighted"= 4, "Concordance"=4)) %>%
kableExtra::scroll_box(width = "100%", height = "375px") |
PWP HR Var. Robusta
|
PWP Original
|
PWP Weighted
|
Concordance
|
||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| rn | HR.x | Lo_ci95.x | Up_ci95.x | p.x | HR.y | Lo_CI95 | Up_CI95 | Avg_HR | Lo_ci95.y | Up_ci95.y | p.y | conc_prob | lo_ci95 | up_ci95 | conc_p |
| terap_disTerapeutic discharge | 0.80 | 0.77 | 0.83 | 0.0000 | 0.79 | 0.76 | 0.82 | 0.88 | 0.82 | 0.94 | 0.0002 | 0.4668 | 0.4493 | 0.4845 | 0.0002301 |
| strata(event)event=2 | 1.63 | 1.57 | 1.69 | 0.0000 | 1.63 | 1.57 | 1.69 | 0.0000 | 0.6196 | 0.6104 | 0.6288 | 0.0000000 | |||
| strata(event)event=3 | 2.11 | 1.98 | 2.25 | 0.0000 | 2.11 | 1.97 | 2.25 | 0.0000 | 0.6780 | 0.6635 | 0.6922 | 0.0000000 | |||
| sexF | 1.21 | 1.16 | 1.25 | 0.0000 | 1.21 | 1.17 | 1.25 | 1.26 | 1.16 | 1.37 | 0.0000 | 0.5577 | 0.5363 | 0.5789 | 0.0000001 |
| edad_inicio | 0.99 | 0.99 | 0.99 | 0.0000 | 0.99 | 0.99 | 0.99 | 0.98 | 0.98 | 0.99 | 0.0000 | 0.4961 | 0.4949 | 0.4973 | 0.0000000 |
| es_conyugalSeparated | 1.00 | 0.96 | 1.05 | 0.9700 | 1.00 | 0.96 | 1.05 | 0.98 | 0.93 | 1.04 | 0.5485 | 0.4959 | 0.4825 | 0.5093 | 0.5485348 |
| es_conyugalSingle | 0.96 | 0.93 | 0.99 | 0.0144 | 0.96 | 0.93 | 0.99 | 0.98 | 0.94 | 1.03 | 0.4073 | 0.4954 | 0.4845 | 0.5063 | 0.4073075 |
| es_conyugalWidower | 0.90 | 0.78 | 1.04 | 0.1476 | 0.90 | 0.79 | 1.04 | 0.90 | 0.77 | 1.04 | 0.1628 | 0.4733 | 0.4361 | 0.5108 | 0.1628442 |
| susCocaine | 1.18 | 1.13 | 1.23 | 0.0000 | 1.18 | 1.14 | 1.23 | 1.20 | 1.14 | 1.26 | 0.0000 | 0.5446 | 0.5326 | 0.5567 | 0.0000000 |
| susMarijuana | 0.88 | 0.82 | 0.94 | 0.0001 | 0.88 | 0.82 | 0.94 | 0.89 | 0.81 | 0.97 | 0.0079 | 0.4696 | 0.4474 | 0.4920 | 0.0079356 |
| susOther | 0.98 | 0.88 | 1.10 | 0.7581 | 0.98 | 0.88 | 1.09 | 0.98 | 0.85 | 1.12 | 0.7257 | 0.4939 | 0.4596 | 0.5282 | 0.7256517 |
| susCocaine paste | 1.39 | 1.34 | 1.44 | 0.0000 | 1.39 | 1.34 | 1.44 | 1.42 | 1.35 | 1.49 | 0.0000 | 0.5862 | 0.5738 | 0.5984 | 0.0000000 |
| escolaridadSecundaria o menor | 0.92 | 0.88 | 0.95 | 0.0000 | 0.92 | 0.89 | 0.95 | 0.94 | 0.90 | 0.98 | 0.0060 | 0.4841 | 0.4728 | 0.4955 | 0.0060294 |
| escolaridadPrimaria o menor | 0.78 | 0.74 | 0.81 | 0.0000 | 0.78 | 0.75 | 0.81 | 0.79 | 0.75 | 0.82 | 0.0000 | 0.4398 | 0.4280 | 0.4517 | 0.0000000 |
| compromiso_biopsicosocialModerate | 1.07 | 1.01 | 1.13 | 0.0149 | 1.07 | 1.01 | 1.13 | 1.05 | 0.94 | 1.16 | 0.3717 | 0.5119 | 0.4858 | 0.5379 | 0.3716803 |
| compromiso_biopsicosocialSevere | 1.31 | 1.24 | 1.39 | 0.0000 | 1.31 | 1.24 | 1.39 | 1.23 | 1.10 | 1.37 | 0.0002 | 0.5518 | 0.5249 | 0.5783 | 0.0001627 |
| tipo_programaEM | 1.27 | 1.21 | 1.33 | 0.0000 | 1.27 | 1.21 | 1.33 | 1.23 | 1.13 | 1.33 | 0.0000 | 0.5508 | 0.5311 | 0.5703 | 0.0000004 |
| estatus_ocupacional2 | 0.91 | 0.88 | 0.94 | 0.0000 | 0.91 | 0.88 | 0.94 | 0.92 | 0.87 | 0.97 | 0.0009 | 0.4790 | 0.4665 | 0.4914 | 0.0009245 |
| estatus_ocupacional3 | 0.96 | 0.92 | 0.99 | 0.0258 | 0.96 | 0.93 | 1.00 | 0.95 | 0.89 | 1.00 | 0.0576 | 0.4860 | 0.4716 | 0.5005 | 0.0576258 |
| freq_cons2 | 1.05 | 0.92 | 1.20 | 0.4469 | 1.05 | 0.92 | 1.19 | 1.03 | 0.89 | 1.18 | 0.7075 | 0.5067 | 0.4717 | 0.5416 | 0.7075146 |
| freq_cons3 | 1.08 | 0.96 | 1.22 | 0.1973 | 1.08 | 0.96 | 1.22 | 1.16 | 1.01 | 1.34 | 0.0383 | 0.5376 | 0.5020 | 0.5729 | 0.0383178 |
| freq_cons4 | 1.12 | 1.00 | 1.25 | 0.0552 | 1.11 | 1.00 | 1.24 | 1.16 | 1.02 | 1.32 | 0.0229 | 0.5373 | 0.5052 | 0.5691 | 0.0228866 |
| freq_cons5 | 1.13 | 1.00 | 1.26 | 0.0418 | 1.12 | 1.00 | 1.26 | 1.14 | 1.01 | 1.29 | 0.0398 | 0.5321 | 0.5015 | 0.5624 | 0.0397938 |
| freq_cons6 | 1.14 | 1.02 | 1.28 | 0.0213 | 1.14 | 1.02 | 1.27 | 1.16 | 1.03 | 1.31 | 0.0141 | 0.5379 | 0.5077 | 0.5679 | 0.0140661 |
| edad_al_ing | 0.99 | 0.99 | 0.99 | 0.0000 | 0.99 | 0.99 | 0.99 | 0.99 | 0.99 | 0.99 | 0.0000 | 0.4981 | 0.4976 | 0.4987 | 0.0000000 |
| terap_disTerapeutic discharge:strata(event)event=2 | 1.01 | 0.93 | 1.09 | 0.8586 | 1.02 | 0.94 | 1.10 | 0.97 | 0.88 | 1.07 | 0.5547 | 0.4924 | 0.4671 | 0.5177 | 0.5547132 |
| terap_disTerapeutic discharge:strata(event)event=3 | 1.04 | 0.90 | 1.20 | 0.5912 | 1.06 | 0.93 | 1.22 | 0.96 | 0.83 | 1.12 | 0.6457 | 0.4910 | 0.4528 | 0.5293 | 0.6456668 |
options(knitr.kable.NA = '')
res_tt_2_cl %>%
dplyr::left_join(res_tt_2_orig, by="rn") %>%
dplyr::left_join(res_tt_3_cl, by="rn") %>%
dplyr::left_join(conc_tt_3_cl, by="rn") %>%
#dplyr::bind_cols(res_gt_2_orig,res_gt_2,res_gt_3,conc_gt_3) %>%
knitr::kable("html") %>%
kableExtra::kable_classic(bootstrap_options = c("striped", "hover"),font_size = 12) %>%
kableExtra::add_header_above( c(" ", "PWP HR Var. Robusta" = 4, "PWP Original" = 3, "PWP Weighted"= 4, "Concordance"=4)) %>%
kableExtra::scroll_box(width = "100%", height = "375px") |
PWP HR Var. Robusta
|
PWP Original
|
PWP Weighted
|
Concordance
|
||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| rn | HR.x | Lo_ci95.x | Up_ci95.x | p.x | HR.y | Lo_CI95 | Up_CI95 | Avg_HR | Lo_ci95.y | Up_ci95.y | p.y | conc_prob | lo_ci95 | up_ci95 | conc_p |
| terap_disTerapeutic discharge | 0.79 | 0.76 | 0.82 | 0.0000 | 0.79 | 0.76 | 0.82 | 0.88 | 0.73 | 1.06 | 0.1780 | 0.4680 | 0.4221 | 0.5146 | 0.1779614 |
| strata(event)event=2 | 2.10 | 2.02 | 2.18 | 0.0000 | 1.98 | 1.88 | 2.08 | 0.0000 | 0.6643 | 0.6529 | 0.6756 | 0.0000000 | |||
| strata(event)event=3 | 2.97 | 2.78 | 3.18 | 0.0000 | 2.76 | 2.56 | 2.98 | 0.0000 | 0.7342 | 0.7192 | 0.7486 | 0.0000000 | |||
| sexF | 1.22 | 1.17 | 1.26 | 0.0000 | 1.21 | 1.17 | 1.26 | 1.39 | 1.08 | 1.78 | 0.0095 | 0.5811 | 0.5199 | 0.6398 | 0.0095341 |
| edad_inicio | 0.99 | 0.98 | 0.99 | 0.0000 | 0.99 | 0.99 | 0.99 | 0.97 | 0.96 | 0.99 | 0.0001 | 0.4935 | 0.4904 | 0.4967 | 0.0000515 |
| es_conyugalSeparated | 1.00 | 0.96 | 1.05 | 0.9282 | 1.00 | 0.96 | 1.05 | 0.95 | 0.86 | 1.06 | 0.4011 | 0.4884 | 0.4613 | 0.5155 | 0.4011180 |
| es_conyugalSingle | 0.97 | 0.94 | 1.00 | 0.0728 | 0.97 | 0.94 | 1.00 | 1.03 | 0.92 | 1.14 | 0.6472 | 0.5063 | 0.4795 | 0.5330 | 0.6471773 |
| es_conyugalWidower | 0.90 | 0.78 | 1.04 | 0.1411 | 0.90 | 0.79 | 1.04 | 0.87 | 0.73 | 1.04 | 0.1385 | 0.4666 | 0.4229 | 0.5108 | 0.1384550 |
| susCocaine | 1.19 | 1.14 | 1.24 | 0.0000 | 1.19 | 1.14 | 1.24 | 1.23 | 1.14 | 1.32 | 0.0000 | 0.5510 | 0.5333 | 0.5687 | 0.0000000 |
| susMarijuana | 0.86 | 0.80 | 0.92 | 0.0000 | 0.86 | 0.80 | 0.92 | 0.84 | 0.74 | 0.96 | 0.0091 | 0.4577 | 0.4263 | 0.4895 | 0.0091226 |
| susOther | 0.96 | 0.85 | 1.08 | 0.4740 | 0.96 | 0.86 | 1.06 | 0.84 | 0.63 | 1.12 | 0.2278 | 0.4558 | 0.3857 | 0.5277 | 0.2277954 |
| susCocaine paste | 1.38 | 1.33 | 1.43 | 0.0000 | 1.38 | 1.33 | 1.42 | 1.50 | 1.32 | 1.71 | 0.0000 | 0.6002 | 0.5686 | 0.6309 | 0.0000000 |
| escolaridadSecundaria o menor | 0.91 | 0.88 | 0.95 | 0.0000 | 0.91 | 0.88 | 0.95 | 0.99 | 0.90 | 1.09 | 0.8559 | 0.4977 | 0.4728 | 0.5226 | 0.8559171 |
| escolaridadPrimaria o menor | 0.76 | 0.73 | 0.80 | 0.0000 | 0.76 | 0.73 | 0.79 | 0.77 | 0.72 | 0.82 | 0.0000 | 0.4357 | 0.4196 | 0.4519 | 0.0000000 |
| compromiso_biopsicosocialModerate | 1.07 | 1.01 | 1.13 | 0.0217 | 1.07 | 1.01 | 1.13 | 0.91 | 0.62 | 1.33 | 0.6140 | 0.4756 | 0.3828 | 0.5701 | 0.6140471 |
| compromiso_biopsicosocialSevere | 1.30 | 1.22 | 1.38 | 0.0000 | 1.30 | 1.23 | 1.38 | 0.99 | 0.66 | 1.49 | 0.9560 | 0.4971 | 0.3968 | 0.5977 | 0.9559755 |
| tipo_programaEM | 1.29 | 1.23 | 1.35 | 0.0000 | 1.29 | 1.23 | 1.35 | 1.15 | 0.94 | 1.41 | 0.1631 | 0.5355 | 0.4856 | 0.5847 | 0.1631049 |
| estatus_ocupacional2 | 0.91 | 0.88 | 0.94 | 0.0000 | 0.91 | 0.88 | 0.94 | 0.89 | 0.78 | 1.03 | 0.1171 | 0.4719 | 0.4371 | 0.5070 | 0.1170531 |
| estatus_ocupacional3 | 0.96 | 0.92 | 1.00 | 0.0422 | 0.96 | 0.93 | 1.00 | 0.89 | 0.75 | 1.06 | 0.1970 | 0.4712 | 0.4280 | 0.5149 | 0.1970022 |
| freq_cons2 | 1.05 | 0.92 | 1.20 | 0.4752 | 1.04 | 0.92 | 1.19 | 0.98 | 0.82 | 1.17 | 0.8140 | 0.4945 | 0.4493 | 0.5399 | 0.8140127 |
| freq_cons3 | 1.08 | 0.96 | 1.23 | 0.2086 | 1.08 | 0.96 | 1.22 | 1.16 | 0.97 | 1.38 | 0.0986 | 0.5368 | 0.4931 | 0.5800 | 0.0986316 |
| freq_cons4 | 1.12 | 0.99 | 1.25 | 0.0639 | 1.11 | 0.99 | 1.24 | 1.21 | 1.01 | 1.45 | 0.0369 | 0.5478 | 0.5029 | 0.5919 | 0.0369471 |
| freq_cons5 | 1.13 | 1.00 | 1.27 | 0.0483 | 1.12 | 1.00 | 1.26 | 1.15 | 0.98 | 1.36 | 0.0945 | 0.5350 | 0.4940 | 0.5756 | 0.0944599 |
| freq_cons6 | 1.14 | 1.02 | 1.28 | 0.0215 | 1.14 | 1.02 | 1.27 | 1.21 | 0.99 | 1.48 | 0.0605 | 0.5482 | 0.4979 | 0.5976 | 0.0605194 |
| edad_al_ing | 0.99 | 0.99 | 0.99 | 0.0000 | 0.99 | 0.99 | 0.99 | 1.00 | 0.99 | 1.00 | 0.4704 | 0.4994 | 0.4978 | 0.5010 | 0.4704100 |
| terap_disTerapeutic discharge:strata(event)event=2 | 1.00 | 0.92 | 1.09 | 0.9946 | 1.02 | 0.94 | 1.10 | 0.98 | 0.82 | 1.19 | 0.8608 | 0.4958 | 0.4491 | 0.5426 | 0.8607673 |
| terap_disTerapeutic discharge:strata(event)event=3 | 1.06 | 0.92 | 1.23 | 0.4179 | 1.12 | 0.98 | 1.29 | 1.00 | 0.81 | 1.25 | 0.9671 | 0.5012 | 0.4463 | 0.5560 | 0.9671260 |
#predict
#pwp_gt_imp3
plot(predict(pwp_gt_imp3, type = "risk", x = "terap_dis", z = "event", arg="risk",
verbose = TRUE, exp = TRUE, pval = TRUE))## Error in h(simpleError(msg, call)): error in evaluating the argument 'x' in selecting a method for function 'plot': error in evaluating the argument 'object' in selecting a method for function 'predict': objeto 'pwp_gt_imp3' no encontrado#https://cran.r-project.org/web/packages/pensim/pensim.pdf
#https://rdrr.io/cran/penalized/man/contrasts.html
#https://rdrr.io/cran/penalized/f/inst/doc/penalized.pdf
#https://cran.r-project.org/web/packages/penalized/index.html
#load("C:/Users/CISS Fondecyt/Mi unidad/Alvacast/SISTRAT 2019 (github)/jose_stata/imputed_ags.RData")
#load("E:/Mi unidad/Alvacast/SISTRAT 2019 (github)/jose_stata/imputed_ags.RData")
library(penalized)
#hay que detachearlo porque genera problemas
devtools::unload("future")## Error in devtools::unload("future"): Package future not found in loaded packages or namespacesunloadNamespace("future")
`%<-%` <- future::`%<-%`
future::plan(future::multisession)
pwp_gt_imp4_1 %<-% {
penalized::optL1( Surv ( tstop2, status==1 ) ~terap_dis*strata(event) + sex + edad_inicio + es_conyugal + sus +
escolaridad + compromiso_biopsicosocial + tipo_programa + estatus_ocupacional +
freq_cons + edad_al_ing + cluster(id)+ strata(event), minlambda=5, fold=3, data=rfimp2)#maxlamda=15,
}
#Error: cannot allocate vector of size 19.3 Gb
#el objeto 'contr.none' de modo 'function' no fue encontrado
pwp_gt_imp4_2 %<-% {
penalized::optL2( Surv ( tstop2, status==1 ) ~terap_dis*strata(event) + sex + edad_inicio + es_conyugal + sus +
escolaridad + compromiso_biopsicosocial + tipo_programa + estatus_ocupacional +
freq_cons + edad_al_ing + cluster(id)+ strata(event), minlambda=5, fold=3, data=rfimp2)#maxlamda=15,
}
#el objeto 'contr.none' de modo 'function' no fue encontrado
#https://arxiv.org/pdf/2102.02297.pdf
pwp_gt_imp5_test %<-% {
pcoxtimecv(Surv ( tstop2, status==1 ) ~terap_dis*strata(event) + sex + edad_inicio + es_conyugal + sus +
escolaridad + compromiso_biopsicosocial + tipo_programa + estatus_ocupacional +
freq_cons + edad_al_ing + cluster(id)+ strata(event), data = rfimp2, alphas = c(0.2, 0.5, 0.8), lambdas = NULL,
devtype = "vv", lamfract = 0.6, refit = TRUE, nclusters = 4)
}
cv_error1 <- plot(cv_fit1, g.col = "black", geom = "line", scales = "free")## Error in h(simpleError(msg, call)): error in evaluating the argument 'x' in selecting a method for function 'plot': objeto 'cv_fit1' no encontradoalp <- cv_fit1$alpha.optimal## Error in eval(expr, envir, enclos): objeto 'cv_fit1' no encontradolam <- cv_fit1$lambda.min## Error in eval(expr, envir, enclos): objeto 'cv_fit1' no encontradoplan(multisession)## Error in plan(multisession): no se pudo encontrar la función "plan"pwp_gt_imp5 %<-% {
fit1 <- pcoxtime(Surv ( tstop2, status==1 ) ~terap_dis*strata(event) + sex + edad_inicio + es_conyugal + sus +
escolaridad + compromiso_biopsicosocial + tipo_programa + estatus_ocupacional +
freq_cons + edad_al_ing + cluster(id)+ strata(event), data = rfimp2,
alpha = alp, lambda = lam
)
}
library(aftgee)
# fit <- aftsrr(Surv ( tstop2, status==1 ) ~terap_dis*strata(event) + sex + edad_inicio + es_conyugal + sus +
# escolaridad + compromiso_biopsicosocial + tipo_programa + estatus_ocupacional +
# freq_cons + edad_al_ing + cluster(id)+ strata(event), data = rfimp2, B = 0, se = c("ISMB", "ZLMB"))
###muuuuuuuy lento
library(spsurv)## Warning: package 'spsurv' was built under R version 4.1.2## Loading required package: loo## This is loo version 2.4.1## - Online documentation and vignettes at mc-stan.org/loo## - As of v2.0.0 loo defaults to 1 core but we recommend using as many as possible. Use the 'cores' argument or set options(mc.cores = NUM_CORES) for an entire session.## - Windows 10 users: loo may be very slow if 'mc.cores' is set in your .Rprofile file (see https://github.com/stan-dev/loo/issues/94).## Loading required package: coda## Loading required package: MASS##
## Attaching package: 'MASS'## The following object is masked from 'package:dplyr':
##
## select##
## Attaching package: 'spsurv'## The following object is masked from 'package:coda':
##
## traceplot## The following object is masked from 'package:penalized':
##
## coef## The following objects are masked from 'package:stats':
##
## coef, confint, vcov## The following object is masked from 'package:base':
##
## modebpaft_gt<-
bpaft(Surv ( tstop2, status==1 ) ~terap_dis*strata(event) + sex + edad_inicio + es_conyugal + sus +
escolaridad + compromiso_biopsicosocial + tipo_programa + estatus_ocupacional +
freq_cons + edad_al_ing + cluster(id)+ strata(event), 2, data = rfimp2, approach = c("mle"))## Priors are ignored due to mle approach.bpaft_gt_df<-round(cbind(exp(coef(bpaft_gt)),exp(confint(bpaft_gt)[,1]),exp(confint(bpaft_gt)[,2])),2)## Warning in sqrt(diag(vcov(spbp))): Se han producido NaNs## Warning in coef(spbp) + se %o% c(-qnorm(1 - alpha/2), qnorm(1 - alpha/2)):
## longitud de objeto mayor no es múltiplo de la longitud de uno menor## Warning in sqrt(diag(vcov(spbp))): Se han producido NaNs## Warning in coef(spbp) + se %o% c(-qnorm(1 - alpha/2), qnorm(1 - alpha/2)):
## longitud de objeto mayor no es múltiplo de la longitud de uno menor## Warning in base::cbind(...): number of rows of result is not a multiple of
## vector length (arg 2)colnames(bpaft_gt_df)<-c("AFT","lo95","hi95")
bpaft_tt<-
bpaft(Surv ( tstart,tstop, status==1 ) ~terap_dis*strata(event) + sex + edad_inicio + es_conyugal + sus +
escolaridad + compromiso_biopsicosocial + tipo_programa + estatus_ocupacional +
freq_cons + edad_al_ing + cluster(id)+ strata(event), 2, data = rfimp2, approach = c("mle"))## Error in new_CppObject_xp(fields$.module, fields$.pointer, ...) :
## Exception: model_spbp_namespace::model_spbp: status[1] is 194, but must be less than or equal to 1 (in 'model_spbp' at line 15)## failed to create the optimizer; optimization not done## Error in array(coef[1:q], q): 'data' must be of a vector type, was 'NULL'bpaft_tt_df<-round(cbind(exp(coef(bpaft_tt)),exp(confint(bpaft_tt)[,1]),exp(confint(bpaft_tt)[,2])),2)## Error in coef(bpaft_tt): objeto 'bpaft_tt' no encontradocolnames(bpaft_tt_df)<-c("AFT","lo95","hi95")## Error in colnames(bpaft_tt_df) <- c("AFT", "lo95", "hi95"): objeto 'bpaft_tt_df' no encontradopaste0("Saved at: ",dirname(rstudioapi::getSourceEditorContext()$path),"/imp_ags_ex_rmd_2022.RData")## [1] "Saved at: E:/Mi unidad/Alvacast/SISTRAT 2019 (github)/jose_stata/imp_ags_ex_rmd_2022.RData"save.image(paste0(dirname(rstudioapi::getSourceEditorContext()$path),"/imp_ags_ex_rmd_2022.RData"))## Error in get(ctr, mode = "function", envir = parent.frame()): el objeto 'contr.none' de modo 'function' no fue encontrado