Reference: U.S. Embassy Official website
Step 1: Complete the Visa Application
Complete a DS-160 form online and print the confirmation page for each person applying for a visa. You will need to determine your visa category, and the select the location where you would like to interview (either Jerusalem or Tel Aviv). Answer the questions to the best of your ability.
You will need to bring your confirmation page to your interview.
Step2: Payment of the Application Fee
Step3: Scheduling of appointment
Schedule an interview online or by phoning the call center at 02-3741221 for Jerusalem or 03-9058062 for Tel Aviv. Once you have scheduled your appointment, you will receive an appointment confirmation at the email address you provided. Please print the appointment confirmation.