1 Methods

2 Results

Table 1: Summary table of all relevant variables by sex.

Variabila	Detalii	F	M	Total	Teste statistice
Age (years)	M (min:max)	60.5 (18:84)	58 (19:87)	59 (18:87)	MW: p=0.377
μ ±DS	58.35 ±12.0	56.85 ±13.5	57.59 ±12.8
Cirrhosis	37 (35.6%)	53 (50.5%)	90 (43.1%)	OR=0.54 [0.31, 0.94] (p=0.036)
Etiology	alcool	12 (11.5%)	35 (33.3%)	47 (22.5%)	V=0.39 (p<0.001)
VHB	12 (11.5%)	20 (19.0%)	32 (15.3%)
VHC	37 (35.6%)	22 (21.0%)	59 (28.2%)
VHB +VHC	5 (4.8%)	1 (1.0%)	6 (2.9%)
VHB+VHD	1 (1.0%)	1 (1.0%)	2 (1.0%)
Viral + alcool	0	4 (3.8%)	4 (1.9%)
Metabolic	16 (15.4%)	12 (11.4%)	28 (13.4%)
Ciroza biliara primitiva/ colangita biliara primitiva	9 (8.7%)	1 (1.0%)	10 (4.8%)
necunoscut	11 (10.6%)	9 (8.6%)	20 (9.6%)
fara boala hepatica	1 (1.0%)	0	1 (0.5%)
alcohol	12 (13.0%)	36 (37.5%)	48 (25.5%)
viral	55 (59.8%)	47 (49.0%)	102 (54.3%)
metabolic	16 (17.4%)	12 (12.5%)	28 (14.9%)
cholestatic liver disease	9 (9.8%)	1 (1.0%)	10 (5.3%)
APP_DZ	22 (21.6%)	24 (23.1%)	46 (22.3%)	OR=0.92 [0.48, 1.77] (p=0.868)
APP_HTAE	34 (33.3%)	37 (35.6%)	71 (34.5%)	OR=0.91 [0.51, 1.61] (p=0.771)
APP_CVD	26 (25.5%)	23 (22.1%)	49 (23.8%)	OR=1.20 [0.63, 2.29] (p=0.625)
APP_COPD	2 (2.0%)	8 (7.7%)	10 (4.9%)	OR=0.24 [0.05, 1.16] (p=0.101)
APP_Renal	2 (2.0%)	6 (6.1%)	8 (4.1%)	OR=0.32 [0.06, 1.62] (p=0.279)
Alcohol	12 (17.4%)	38 (45.8%)	50 (32.9%)	OR=0.25 [0.12, 0.53] (p<0.001)
Dislipidemia	8 (24.2%)	4 (10.3%)	12 (16.7%)	OR=2.80 [0.76, 10.33] (p=0.128)
Weight	M (min:max)	74.5 (45:115)	84 (54:123)	80 (45:123)	T-test: p<0.001
μ ±DS	73.57 ±13.7	85.89 ±15.5	79.73 ±15.8
Height	M (min:max)	162 (150:175)	175 (158:192)	168 (150:192)	MW: p<0.001
μ ±DS	162.42 ±5.57	174.51 ±6.83	168.69 ±8.69
BMI	M (min:max)	27.01 (15.57:42.24)	28.37 (19.36:40.86)	27.68 (15.57:42.24)	T-test: p=0.783
μ ±DS	27.91 ±5.22	28.13 ±4.78	28.02 ±4.99
Fibroscan_Probe	M	100 (96.2%)	93 (88.6%)	193 (92.3%)	OR=3.23 [1.00, 10.35] (p=0.066)
XL	4 (3.8%)	12 (11.4%)	16 (7.7%)
Fibroscan_Value	M (min:max)	7.8 (2.5:75)	13.3 (2.8:75)	9.8 (2.5:75)	MW: p=0.002
μ ±DS	13.57 ±13.4	23.48 ±22.8	18.55 ±19.3
Fibroscan fibrosis stage	F0-F1 (<7)	47 (45.2%)	31 (29.5%)	78 (37.3%)	V=0.18 (p=0.039)
F2 (7-10)	15 (14.4%)	14 (13.3%)	29 (13.9%)
F3-F4 (>10)	42 (40.4%)	60 (57.1%)	102 (48.8%)
IQR_LSM_TE	M (min:max)	0.9 (0:10.1)	1.3 (0:18.3)	1.1 (0:18.3)	MW: p=0.012
μ ±DS	1.91 ±2.46	3.21 ±3.84	2.56 ±3.29
IQR/MED_TE	M (min:max)	13 (0:30)	13 (0:31)	13 (0:31)	MW: p=0.506
μ ±DS	13.27 ±6.22	13.94 ±7.03	13.61 ±6.63
Nr_Invalid_LSM_TE_measurements	M (min:max)	1 (0:38)	0 (0:39)	0 (0:39)	MW: p=0.158
μ ±DS	4.26 ±7.79	3.13 ±7.18	3.69 ±7.49
CAP_Value	M (min:max)	265.5 (100:400)	266 (151:400)	266 (100:400)	Welch: p=0.137
μ ±DS	257.58 ±67.3	270.26 ±54.7	263.95 ±61.4
CAP Steatosis stage	No steatosis	50 (48.1%)	50 (47.6%)	100 (47.8%)	V=0.02 (p=0.991)
S1 (260-284)	17 (16.3%)	17 (16.2%)	34 (16.3%)
S2 (285-294)	4 (3.8%)	5 (4.8%)	9 (4.3%)
S3 (≥295)	33 (31.7%)	33 (31.4%)	66 (31.6%)
CAP_IQR/MED	M (min:max)	23 (0:82)	31 (7:90)	26 (0:90)	MW: p=0.001
μ ±DS	28.12 ±17.5	33.93 ±16.4	31.04 ±17.2
HRI number measurements	M (min:max)	3 (1:3)	3 (1:4)	3 (1:4)	MW: p=0.106
μ ±DS	2.42 ±0.898	2.14 ±1.04	2.29 ±0.975
HRI Mean	M (min:max)	1.21 (0.6:2.79)	1.17 (0.66:2.46)	1.19 (0.6:2.79)	MW: p=0.438
μ ±DS	1.22 ±0.327	1.21 ±0.379	1.22 ±0.351
HRI - B Ratio 1	M (min:max)	1.23 (0.63:2.79)	1.19 (0.66:2.87)	1.21 (0.63:2.87)	MW: p=0.570
μ ±DS	1.26 ±0.385	1.23 ±0.377	1.25 ±0.38
HRI Depth liver 1	M (min:max)	7.6 (4.7:10.7)	7.8 (4.5:11.1)	7.6 (4.5:11.1)	T-test: p=0.060
μ ±DS	7.38 ±1.3	7.80 ±1.38	7.58 ±1.35
HRI Depth Renal 1	M (min:max)	7.4 (4.2:10)	7.65 (4.9:10.9)	7.45 (4.2:10.9)	T-test: p=0.123
μ ±DS	7.24 ±1.24	7.58 ±1.38	7.40 ±1.31
HRI - B Ratio 2	M (min:max)	1.15 (0.64:1.87)	1.06 (0.63:2.29)	1.1 (0.63:2.29)	MW: p=0.305
μ ±DS	1.17 ±0.29	1.15 ±0.338	1.16 ±0.31
HRI Depth liver 2	M (min:max)	7.3 (4.3:9.7)	7.3 (4.2:11.1)	7.3 (4.2:11.1)	T-test: p=0.417
μ ±DS	7.24 ±1.17	7.46 ±1.46	7.33 ±1.29
HRI Depth Renal 2	M (min:max)	7.2 (4:9.6)	7.4 (4.4:11.2)	7.3 (4:11.2)	T-test: p=0.326
μ ±DS	7.16 ±1.19	7.43 ±1.49	7.27 ±1.32
HRI - B Ratio 3	M (min:max)	1.17 (0.52:2.18)	1.13 (0.47:3.13)	1.15 (0.47:3.13)	MW: p=0.366
μ ±DS	1.19 ±0.325	1.19 ±0.485	1.19 ±0.398
HRI Depth liver 3	M (min:max)	7.2 (4.7:9.3)	7.4 (4.5:10.9)	7.2 (4.5:10.9)	T-test: p=0.118
μ ±DS	7.15 ±1.14	7.58 ±1.47	7.33 ±1.3
HRI Depth Renal 3	M (min:max)	7.4 (4.3:9.4)	7.5 (4.7:10.9)	7.4 (4.3:10.9)	T-test: p=0.132
μ ±DS	7.14 ±1.13	7.55 ±1.47	7.32 ±1.29
Number Attenuation measurements	M (min:max)	5 (1:7)	5 (1:7)	5 (1:7)	MW: p=0.915
μ ±DS	4.79 ±1.05	4.83 ±0.961	4.81 ±1.0
Attenuation Mean	M (min:max)	0.42 (0.21:0.74)	0.41 (0.16:0.77)	0.41 (0.16:0.77)	MW: p=0.364
μ ±DS	0.448 ±0.126	0.427 ±0.111	0.437 ±0.119
Attenuation_1	M (min:max)	0.43 (0.21:0.76)	0.43 (0.21:0.74)	0.43 (0.21:0.76)	MW: p=0.816
μ ±DS	0.437 ±0.138	0.43 ±0.124	0.433 ±0.131
Atenuation_SOS_1 m/s	M (min:max)	1518 (1474:1594)	1532 (1467:1614)	1527 (1467:1614)	MW: p=0.002
μ ±DS	1523.70 ±26.2	1535.05 ±26.9	1529.40 ±27.1
Attenuation_2	M (min:max)	0.45 (0.2:0.77)	0.42 (0.2:0.89)	0.43 (0.2:0.89)	MW: p=0.143
μ ±DS	0.452 ±0.137	0.424 ±0.134	0.437 ±0.136
Atenuation_SOS_2_m/s	M (min:max)	1520 (1469:1665)	1530.5 (1474:1602)	1525 (1469:1665)	MW: p<0.001
μ ±DS	1523.60 ±31.5	1535.39 ±26.4	1529.52 ±29.6
Attenuation_3	M (min:max)	0.45 (0.21:0.8)	0.41 (0.2:0.97)	0.43 (0.2:0.97)	MW: p=0.238
μ ±DS	0.451 ±0.139	0.429 ±0.131	0.44 ±0.135
Atenuation_SOS_3_m/s	M (min:max)	1518 (1473:1596)	1535 (1481:1617)	1529 (1473:1617)	MW: p<0.001
μ ±DS	1523.80 ±28.1	1536.74 ±26.6	1530.24 ±28.0
Attenuation_4	M (min:max)	0.46 (0.22:0.79)	0.43 (0.21:0.77)	0.44 (0.21:0.79)	MW: p=0.118
μ ±DS	0.464 ±0.134	0.433 ±0.129	0.448 ±0.132
Atenuation_SOS_4_m/s	M (min:max)	1524 (1473:1591)	1536 (1474:1676)	1529 (1473:1676)	MW: p=0.006
μ ±DS	1524.62 ±26.9	1536.00 ±28.5	1530.43 ±28.2
Attenuation 5	M (min:max)	0.43 (0.22:0.74)	0.42 (0.25:0.74)	0.43 (0.22:0.74)	MW: p=0.390
μ ±DS	0.458 ±0.131	0.441 ±0.115	0.449 ±0.123
Atenuation 5 m/s	M (min:max)	1520 (1459:1593)	1538 (1480:1653)	1529 (1459:1653)	MW: p<0.001
μ ±DS	1521.48 ±27.4	1539.65 ±29.2	1530.62 ±29.6
Attenuation 6	M (min:max)	0.44 (0.27:0.81)	0.46 (0.31:0.72)	0.44 (0.27:0.81)	MW: p=0.984
μ ±DS	0.475 ±0.171	0.45 ±0.112	0.463 ±0.144
Atenuation 6 m/s	M (min:max)	1524 (1469:1589)	1517 (1471:1563)	1521 (1469:1589)	T-test: p=0.883
μ ±DS	1525.59 ±28.2	1524.07 ±29.8	1524.88 ±28.5
Attenuation 7	M (min:max)	0.47 (0.42:0.81)	0.53 (0.36:0.66)	0.49 (0.36:0.81)	T-test: p=0.814
μ ±DS	0.542 ±0.181	0.518 ±0.12	0.529 ±0.14
Atenuation 7 m/s	M (min:max)	1523 (1515:1525)	1545 (1494:1555)	1524 (1494:1555)	Welch: p=0.364
μ ±DS	1521.50 ±4.51	1533.20 ±25.3	1528.00 ±19.1
Elastography liver number measurements	M (min:max)	3 (1:5)	3 (1:5)	3 (1:5)	MW: p=0.237
μ ±DS	3.45 ±1.03	3.58 ±1.41	3.52 ±1.24
Elastography liver median 1	M (min:max)	9 (3.3:55.7)	13.2 (4.5:76.7)	10.4 (3.3:76.7)	MW: p=0.002
μ ±DS	13.41 ±11.1	19.59 ±16.0	16.52 ±14.1
Elastography liver SD 1	M (min:max)	0.8 (0:7)	1 (0.1:10.7)	0.9 (0:10.7)	MW: p=0.019
μ ±DS	1.29 ±1.5	2.00 ±2.33	1.65 ±1.99
Elastography liver IQR 1	M (min:max)	1.4 (0.1:16.6)	2 (0.1:24.9)	1.7 (0.1:24.9)	MW: p=0.108
μ ±DS	2.39 ±2.78	3.64 ±4.67	3.01 ±3.88
Viscosity liver Median 1	M (min:max)	2.1 (1.1:4.1)	2.3 (1.2:5)	2.2 (1.1:5)	MW: p=0.010
μ ±DS	2.20 ±0.639	2.59 ±0.961	2.39 ±0.835
Viscosity liver SD 1	M (min:max)	0.6 (0.2:1.3)	0.6 (0.1:1.6)	0.6 (0.1:1.6)	MW: p=0.368
μ ±DS	0.585 ±0.229	0.637 ±0.302	0.61 ±0.268
Viscosity liver Depth 1	M (min:max)	4.2 (3.1:5.8)	4.2 (3.4:43.9)	4.2 (3.1:43.9)	MW: p=0.636
μ ±DS	4.35 ±0.594	4.74 ±4.12	4.54 ±2.92
Viscosity liver diam 1 mm	M (min:max)	15 (5:29)	15 (5:24)	15 (5:29)	MW: p=0.843
μ ±DS	15.34 ±4.7	15.18 ±3.96	15.26 ±4.34
Viscosity liver SI 1 (5)	M (min:max)	90 (32:98)	92 (12:99)	91 (12:99)	MW: p=0.057
μ ±DS	86.74 ±11.6	89.05 ±11.1	87.88 ±11.4
Spleen diameter	M (min:max)	10.73 (7.26:20.03)	12.64 (6.37:21.8)	12.02 (6.37:21.8)	MW: p<0.001
μ ±DS	11.72 ±2.89	13.42 ±3.12	12.60 ±3.12
Spleen area	M (min:max)	62.44 (29.89:136.44)	65.96 (15.73:193.16)	65.96 (15.73:193.16)	MW: p=0.673
μ ±DS	68.62 ±28.9	73.40 ±36.7	72.08 ±34.6
VP Diam cm	M (min:max)	1.04 (0.76:1.45)	1.29 (0.52:1.76)	1.15 (0.52:1.76)	T-test: p<0.001
μ ±DS	1.07 ±0.189	1.25 ±0.24	1.16 ±0.231
VP Speed	M (min:max)	27.91 (14.38:74.5)	26.45 (14.62:49.44)	26.49 (14.38:74.5)	MW: p=0.731
μ ±DS	29.84 ±14.2	27.29 ±9.1	28.39 ±11.5
VP RI	M (min:max)	0.01 (0:0.04)	0.01 (0:0.1)	0.01 (0:0.1)	MW: p=0.093
μ ±DS	0.00778 ±0.00943	0.0243 ±0.0311	0.0167 ±0.0249
Elastography spleen number measurements	M (min:max)	3 (1:5)	3 (1:5)	3 (1:5)	MW: p=0.987
μ ±DS	2.83 ±1.17	2.84 ±1.38	2.84 ±1.29
Elastography spleen median 1	M (min:max)	33.8 (1:60.3)	41.7 (3:77.1)	39.6 (1:77.1)	T-test: p=0.158
μ ±DS	35.43 ±14.2	40.96 ±15.1	38.78 ±14.9
Elastography spleen SD 1	M (min:max)	6.4 (1.3:26)	4.2 (0.7:17.6)	4.8 (0.7:26)	MW: p=0.054
μ ±DS	7.85 ±5.88	5.25 ±3.89	6.28 ±4.9
Elastography spleen IQR 1	M (min:max)	4.65 (3.1:6.2)	5.8 (3.8:23.8)	5.1 (3.1:23.8)	MW: p=0.533
μ ±DS	4.65 ±2.19	9.80 ±9.5	8.08 ±7.88
Viscosity spleen Median 1	M (min:max)	3.2 (1.1:4.4)	3.5 (1.4:5)	3.3 (1.1:5)	T-test: p=0.146
μ ±DS	2.92 ±0.97	3.35 ±0.905	3.21 ±0.938
Viscosity spleen SD 1	M (min:max)	0.8 (0.3:1.2)	0.65 (0:1.5)	0.7 (0:1.5)	T-test: p=0.401
μ ±DS	0.793 ±0.24	0.703 ±0.373	0.733 ±0.334
Viscosity spleen Depth 1	M (min:max)	41.35 (4:53)	38.4 (2.9:64.9)	39 (2.9:64.9)	MW: p=0.493
μ ±DS	36.34 ±16.4	33.84 ±18.4	34.69 ±17.6
Viscosity spleen SI 1	M (min:max)	82 (44:95)	91 (36:98)	87 (36:98)	MW: p=0.115
μ ±DS	78.38 ±14.7	83.39 ±15.5	81.68 ±15.3
Hb	M (min:max)	13.6 (8.9:16.7)	14.5 (7.5:19.6)	13.9 (7.5:19.6)	MW: p<0.001
μ ±DS	13.41 ±1.54	14.18 ±2.23	13.79 ±1.94
PTL	M (min:max)	216 (54:536)	149 (2.39:440)	181.5 (2.39:536)	MW: p=0.002
μ ±DS	207.54 ±94.8	164.71 ±92.5	186.62 ±95.9
GOT	M (min:max)	28.5 (15:570)	33 (13:183)	31 (13:570)	MW: p=0.063
μ ±DS	43.10 ±64.4	43.23 ±29.1	43.16 ±49.5
GPT	M (min:max)	23 (9:291)	25.5 (7:387)	24 (7:387)	MW: p=0.103
μ ±DS	31.99 ±35.9	40.61 ±52.5	36.39 ±45.3
BT	M (min:max)	0.8 (0.3:11.1)	1.5 (0.3:6.6)	0.9 (0.3:11.1)	MW: p<0.001
μ ±DS	1.20 ±1.58	1.73 ±1.41	1.46 ±1.52
BD	M (min:max)	0.26 (0.09:8.96)	0.39 (0.13:3.97)	0.31 (0.09:8.96)	MW: p=0.007
μ ±DS	0.553 ±1.28	0.629 ±0.693	0.591 ±1.03
GGT	M (min:max)	39 (13:846)	58.5 (18:1914)	46 (13:1914)	MW: p=0.002
μ ±DS	83.54 ±147.8	134.21 ±264.0	108.40 ±213.7
FA	M (min:max)	225 (108:899)	221 (104:1042)	222 (104:1042)	MW: p=0.975
μ ±DS	268.60 ±150.0	254.23 ±132.2	261.55 ±141.3
ALB	M (min:max)	4.2 (3.2:5.1)	4.3 (2.6:5.3)	4.2 (2.6:5.3)	MW: p=0.522
μ ±DS	4.13 ±0.506	4.21 ±0.771	4.17 ±0.65
INR	M (min:max)	1.06 (0.9:2.52)	1.2 (0.9:2.7)	1.14 (0.9:2.7)	MW: p=0.012
μ ±DS	1.18 ±0.272	1.29 ±0.313	1.24 ±0.299
COL	M (min:max)	191 (129:326)	184 (18:288)	186 (18:326)	MW: p=0.135
μ ±DS	199.16 ±53.7	179.12 ±54.3	189.38 ±54.6
TG	M (min:max)	111.5 (31:285)	102.5 (33:380)	106.5 (31:380)	MW: p=0.352
μ ±DS	125.18 ±54.6	117.10 ±68.4	121.04 ±61.8
Fe	M (min:max)	92 (26:206)	110 (22:246)	99 (22:246)	MW: p=0.094
μ ±DS	95.12 ±37.6	113.38 ±52.4	103.22 ±45.4
Crea	M (min:max)	0.7 (0.52:3.43)	0.84 (0.54:1.37)	0.77 (0.52:3.43)	MW: p<0.001
μ ±DS	0.772 ±0.337	0.875 ±0.178	0.822 ±0.276
Uree	M (min:max)	31 (10:84)	32 (18:92)	31 (10:92)	MW: p=0.729
μ ±DS	35.23 ±15.3	35.77 ±15.5	35.48 ±15.3
Na	M (min:max)	136 (126:142)	137 (89:142)	136 (89:142)	MW: p=0.841
μ ±DS	136.26 ±2.93	135.39 ±7.09	135.81 ±5.49
Glicemie	M (min:max)	106 (75.8:336)	103.4 (75.7:361.7)	104 (75.7:361.7)	MW: p=0.815
μ ±DS	120.15 ±45.1	116.49 ±39.2	118.35 ±42.2
CRP	M (min:max)	0.39 (0.23:4.87)	0.38 (0.2:22.2)	0.38 (0.2:22.2)	MW: p=0.661
μ ±DS	0.689 ±0.959	1.74 ±4.4	1.20 ±3.17
OR = odds-ratio [cu IC 95%] și p calculat prin testul Fisher); V = Cramér V (p calculat prin testul Chi²);

.

T

author

1 Methods

2 Results