Introduction

Patient Characteristics

Table 1. Patient Characteristics
Group Characteristic N N = 73
Pre-Operative Age 73 58.00 (19.00)
Sex 73
Female 25.0 (34.2%)
Male 48.0 (65.8%)
BMI 73 28.60 (8.69)
Debakey Classification 73
I 53.0 (72.6%)
III 20.0 (27.4%)
Dissection Chronicity 73
Acute 22.0 (30.1%)
Subacute 1.0 (1.4%)
Chronic 50.0 (68.5%)
Indication for Surgery 73
Growth 51.0 (69.9%)
Size 11.0 (15.1%)
Compression 11.0 (15.1%)
Time to Surgery 73 351.00 (1,787.00)
Length of Stay 73 8.00 (7.00)
Procedure Time 26 170.00 (79.00)
Contrast Volume 22 46.00 (44.00)
Fluoroscopy Time 22 27.50 (20.00)
Coronary Artery Disease 73 16.0 (21.9%)
Peripheral Vascular Disease 73 19.0 (26.0%)
Stroke (within 30 days) 73 0.0 (0.0%)
Chronic Obstructive Pulmonary Disease 73 8.0 (11.0%)
Hypertension 73 61.0 (83.6%)
Diabetes 70 5.0 (7.1%)
Hyperlipidemia 73 31.0 (42.5%)
Chronic Renal Failure 73 13.0 (17.8%)
Aortic Surgery 73 45.0 (61.6%)
Connective Tissue Disorder 73 8.0 (11.0%)
Type A Dissection 73 38.0 (52.1%)
Malperfusion 73 10.0 (13.7%)
Post-Operative Type 1 Endoleak 73 11.0 (15.1%)
Type 2 Endoleak 73 8.0 (11.0%)
Other Endoleak 73 14.0 (19.2%)
Mortality 73 4.0 (5.5%)
30-Day Mortality 73 3.0 (4.1%)
Paraparesis 73 3.0 (4.1%)
Mesenteric Ischemia 73 5.0 (6.8%)
Limb Ischemia 73 3.0 (4.1%)
Stroke 73 3.0 (4.1%)
Transient Ischemic Attack 73 1.0 (1.4%)
Hemorrhage 73 6.0 (8.2%)
Dialysis 73 2.0 (2.7%)
1 Continuous data is displayed as Median (IQR); Categorical data is displayed as N (%)

Optional: Patient characteristics broken down by Debakey classification.

Table. Patient Characteristics by Debakey Classification
Debakey Classification
Group Characteristic N Overall, N = 73 I, N = 53 III, N = 20 p-value
Pre-Operative Patient ID 73 37.00 (36.00); 1.00-73.00 36.00 (32.00); 1.00-73.00 40.50 (45.00); 3.00-72.00 0.7
Age 73 58.00 (19.00); 21.00-88.00 56.00 (15.00); 21.00-88.00 61.50 (21.50); 37.00-76.00 0.3
Sex 73 0.081
Female 25.0 (34.2%) 15.0 (28.3%) 10.0 (50.0%)
Male 48.0 (65.8%) 38.0 (71.7%) 10.0 (50.0%)
BMI 73 28.60 (8.69); 21.50-48.94 28.90 (10.97); 21.50-48.94 28.34 (6.57); 23.52-41.17 0.8
Dissection Chronicity 73 0.4
Acute 22.0 (30.1%) 16.0 (30.2%) 6.0 (30.0%)
Subacute 1.0 (1.4%) 0.0 (0.0%) 1.0 (5.0%)
Chronic 50.0 (68.5%) 37.0 (69.8%) 13.0 (65.0%)
Indication for Surgery 73 0.6
Growth 51.0 (69.9%) 35.0 (66.0%) 16.0 (80.0%)
Size 11.0 (15.1%) 9.0 (17.0%) 2.0 (10.0%)
Compression 11.0 (15.1%) 9.0 (17.0%) 2.0 (10.0%)
Time to Surgery 73 351.00 (1,787.00); 0.00-9,784.00 351.00 (1,785.00); 0.00-9,784.00 216.50 (1,888.50); 0.00-7,193.00 0.8
Length of Stay 73 8.00 (7.00); 1.00-42.00 8.00 (8.00); 3.00-42.00 8.50 (5.25); 1.00-26.00 0.5
Procedure Time 26 170.00 (79.00); 82.00-453.00 170.00 (92.75); 82.00-453.00 149.00 (49.75); 117.00-178.00 0.3
Contrast Volume 22 46.00 (44.00); 25.00-108.00 42.00 (40.00); 25.00-108.00 50.00 (37.50); 25.00-100.00 >0.9
Fluoroscopy Time 22 27.50 (20.00); 15.00-71.00 27.00 (21.00); 15.00-71.00 39.00 (9.00); 24.00-42.00 0.6
Coronary Artery Disease 73 16.0 (21.9%) 12.0 (22.6%) 4.0 (20.0%) >0.9
Peripheral Vascular Disease 73 19.0 (26.0%) 14.0 (26.4%) 5.0 (25.0%) >0.9
Stroke (within 30 days) 73 0.0 (0.0%) 0.0 (0.0%) 0.0 (0.0%) >0.9
Chronic Obstructive Pulmonary Disease 73 8.0 (11.0%) 5.0 (9.4%) 3.0 (15.0%) 0.7
Hypertension 73 61.0 (83.6%) 42.0 (79.2%) 19.0 (95.0%) 0.2
Diabetes 70 5.0 (7.1%) 5.0 (9.8%) 0.0 (0.0%) 0.3
Hyperlipidemia 73 31.0 (42.5%) 19.0 (35.8%) 12.0 (60.0%) 0.063
Chronic Renal Failure 73 13.0 (17.8%) 9.0 (17.0%) 4.0 (20.0%) 0.7
Aortic Surgery 73 45.0 (61.6%) 39.0 (73.6%) 6.0 (30.0%) <0.001
Connective Tissue Disorder 73 8.0 (11.0%) 7.0 (13.2%) 1.0 (5.0%) 0.4
Type A Dissection 73 38.0 (52.1%) 38.0 (71.7%) 0.0 (0.0%) <0.001
Malperfusion 73 10.0 (13.7%) 9.0 (17.0%) 1.0 (5.0%) 0.3
Post-Operative Type 1 Endoleak 73 11.0 (15.1%) 9.0 (17.0%) 2.0 (10.0%) 0.7
Type 2 Endoleak 73 8.0 (11.0%) 8.0 (15.1%) 0.0 (0.0%) 0.10
Other Endoleak 73 14.0 (19.2%) 13.0 (24.5%) 1.0 (5.0%) 0.094
Mortality 73 4.0 (5.5%) 3.0 (5.7%) 1.0 (5.0%) >0.9
30-Day Mortality 73 3.0 (4.1%) 2.0 (3.8%) 1.0 (5.0%) >0.9
Paraparesis 73 3.0 (4.1%) 2.0 (3.8%) 1.0 (5.0%) >0.9
Mesenteric Ischemia 73 5.0 (6.8%) 3.0 (5.7%) 2.0 (10.0%) 0.6
Limb Ischemia 73 3.0 (4.1%) 1.0 (1.9%) 2.0 (10.0%) 0.2
Stroke 73 3.0 (4.1%) 2.0 (3.8%) 1.0 (5.0%) >0.9
Transient Ischemic Attack 73 1.0 (1.4%) 0.0 (0.0%) 1.0 (5.0%) 0.3
Hemorrhage 73 6.0 (8.2%) 6.0 (11.3%) 0.0 (0.0%) 0.2
Dialysis 73 2.0 (2.7%) 2.0 (3.8%) 0.0 (0.0%) >0.9
1 Median (IQR); Minimum-Maximum; n (%)
2 Wilcoxon rank sum test; Pearson’s Chi-squared test; Fisher’s exact test

Aortic Measurements

Patients were followed post-operatively with contrast gated computed tomography (CT). At each time point, the cross-sectional area of the aorta, true lumen, and false lumen were recorded, as well as whether flow was present in the false lumen, for each of 9 aortic zones.

Characteristic N = 2211
Visit
1 73 (33%)
2 70 (32%)
3 50 (23%)
4 25 (11%)
5 3 (1.4%)
Post-Operative Day 3.00 (0.00, 121.00)
Total Aortic Area 7,807.50 (5,855.25, 9,684.25)
True Lumen Area 4,042.50 (2,848.50, 5,056.50)
False Lumen Area 3,455.50 (1,993.50, 4,915.00)
True Lumen Fraction 0.55 (0.39, 0.67)
False Lumen Fraction 0.44 (0.31, 0.60)
Patent Fraction 0.50 (0.33, 0.75)
Thrombosed Fraction 0.33 (0.05, 0.50)

1 n (%); Median (IQR)

Tests for Normality

Shapiro-Wilks Test for Normality: Pre-Operative Data
Variable Statistic p-value
Age 0.987 0.680
BMI 0.943 0.003
Time to Surgery 0.891 0.020
Length of Stay 0.839 0.001
Procedure Time 0.781 0.000
Contrast Volume 0.680 0.000
Fluoroscopy Time 0.863 0.006
Shapiro-Wilks Test for Normality: Aortic Data
Variable Statistic p-value
Visit 0.954 0.000
Post-Operative Day 0.986 0.030
Total Aortic Area 0.944 0.000
True Lumen Area 0.923 0.000
False Lumen Area 0.660 0.000
True Lumen Fraction 0.994 0.524
False Lumen Fraction 0.983 0.011
Patent Fraction 0.986 0.030
Thrombosed Fraction 0.863 0.000

Repeated Measures ANOVA
Variable F Value p-value
Total Aortic Area 6.383 9.58e-05
True Lumen Area 80.040 <2e-16
False Lumen Area 27.680 <2e-16
True Lumen Fraction 73.650 <2e-16
False Lumen Fraction 79.020 <2e-16
Patent Fraction 21.530 8.06e-14
Thrombosed Fraction 26.970 <2e-16