3/9/2021
Histamine Fish Poisoning
- Most frequently cause of illness in seafood
- Caused by ingestion of histamine (>500 ppm)
- Histamine - produced during storage of fish
- Can be produced by low temperature histamine-producing bacteria (HPB)
Low Temperature HPB
- Photobacterium kishitanii was the most prolific histamine producer (HPB)
- P. kishitanii was inoculated into tuna muscle and incubated at 4C for 14 days (HPB)
- Data was fitted to segmented model
- Application predicts histamine produced in tuna after designated storage time at 4C (HPB)
Histamine in Tuna
- Histamine is produced by histamine-producing bacteria at 4C with 2 log inoculation
- Please see link here for application

Purpose and Uses
- Predicts histamine production in tuna stored at 4C
- Producers - predict safe storage time
- Regulatory - give guidance or save storage of tuna (HPB)
Thank you