77 Preterm Subjects (excluding retrospective cohort and healthy cohort)

*Number of preterm subjects were confirmed via the PNAC Screening Log and the Final Biomarkers All Combined excel files found in the shared pnacbiomarkers drive and pnac REDCap database

*73 subjects that had the “Screened for ROP” field blank, were assumed to have been screened due to being in preterm cohort. Need clarification if this assumption is correct, or if patients who are <32/35 weeks GA and <1.5kg are only screened.

DHA: Mean, Median (IQR) by Week
Week of Life Mean (SD) Median (IQR)
0 3.77 (1.30) 3.53 (2.81, 4.30)
1 3.8 (1.2) 3.59 (2.75, 4.57)
2 3.22 (1.07) 3.24 (2.56, 4.09)
3 3.03 (1.09) 2.665 (2.09, 3.72)
4 2.63 (0.84) 2.48 (1.93, 3.46)
5 2.47 (0.74) 2.14 (1.97, 2.56)
6 2.51 (0.56) 2.52 (2.21, 2.75)
7 2.7 (0.57) 2.79 (2.33, 3.01)
8 3.04 (0.71) 3.18 (2.73, 3.43)
9 2.93 (0.57) 2.93 (2.68, 3.18)
10 2.62 (0.4) 2.63 (2.34, 2.91)
11 2.35 (0.36) 2.25 (2.14, 2.46)
12 2.48 (0.56) 2.35 (2.17, 2.72)
13 2.59 (NA) 2.59 (2.59, 2.59)
14 3.06 (NA) 3.06 (3.06, 3.06)
16 2.767(0.91) 2.765 (2.44, 3.09)
Arachidonic Acid: Mean, Median (IQR) by Week
Week of Life Mean (SD) Median (IQR)
0 21.79 (1.11) 21.64 (21.02, 22.34)
1 19.41 (1.83) 19.36 (18.40, 20.92)
2 17.23 (2.05) 17.48 (15.86, 18.63)
3 16.62 (1.75) 16.68 (15.55, 17.64)
4 15.33 (1.58) 14.98 (14.49, 15.77)
5 15.48 (2.1) 16.27 (14.15, 16.84)
6 15.52 (1.87) 15.73 (14.05, 16.75)
7 15.12 (1.62) 15.18 (13.94, 16.20)
8 14.35 (0.87) 13.93 (13.85, 14.35)
9 15.11 (1.52) 14.95 (14.10, 15.96)
10 15.57 (1.41) 15.45 (15.01, 15.57)
11 15.21 (1.19) 14.93 (14.51, 15.21)
12 14.75 (1.19) 14.07 (14.06, 14.75)
13 16 (NA) 16 (16, 16)
14 18.26 (NA) 18.26 (18.26, 18.26)
16 17.01 (0.88) 17.01 (16.70, 17.32)