Description

This report describe prediction of breast cancer diagnosis using Machine Learning Algorithm. we investigated 4 Algorithm : Logistic Regression, Decision tree, Random Foresst, and support Vector Machine (SVM) The dataset used in this report is Breast Cancer Wisconsin hosted in kaggle.

The dataset can be dowloaded

[here.] (https://www.kaggle.com/uciml/breast-cancer-wisconsin-data)

Report Outline :
1. Data Extraction
2. Exploratory Data Analysis
3. Data Processing
4. Modelling
5. Evaluation
6. Compare with PCA
7. Recommendation

1. Data Extraction

The Dataset is downlaoded from kaggle and saved in the data folder. we used read.csv function to read the dataset and put in bcw_df data frame

bcw_df <- read.csv("Data/data.csv")

To see the number of rows and column, we used dim fuction. The dataset has 569 rows and 33 columns

dim(bcw_df)
## [1] 569  33

2. Exploratory Data Analysis

To find out the column names and types, we used **str() function

str(bcw_df)
## 'data.frame':    569 obs. of  33 variables:
##  $ id                     : int  842302 842517 84300903 84348301 84358402 843786 844359 84458202 844981 84501001 ...
##  $ diagnosis              : chr  "M" "M" "M" "M" ...
##  $ radius_mean            : num  18 20.6 19.7 11.4 20.3 ...
##  $ texture_mean           : num  10.4 17.8 21.2 20.4 14.3 ...
##  $ perimeter_mean         : num  122.8 132.9 130 77.6 135.1 ...
##  $ area_mean              : num  1001 1326 1203 386 1297 ...
##  $ smoothness_mean        : num  0.1184 0.0847 0.1096 0.1425 0.1003 ...
##  $ compactness_mean       : num  0.2776 0.0786 0.1599 0.2839 0.1328 ...
##  $ concavity_mean         : num  0.3001 0.0869 0.1974 0.2414 0.198 ...
##  $ concave.points_mean    : num  0.1471 0.0702 0.1279 0.1052 0.1043 ...
##  $ symmetry_mean          : num  0.242 0.181 0.207 0.26 0.181 ...
##  $ fractal_dimension_mean : num  0.0787 0.0567 0.06 0.0974 0.0588 ...
##  $ radius_se              : num  1.095 0.543 0.746 0.496 0.757 ...
##  $ texture_se             : num  0.905 0.734 0.787 1.156 0.781 ...
##  $ perimeter_se           : num  8.59 3.4 4.58 3.44 5.44 ...
##  $ area_se                : num  153.4 74.1 94 27.2 94.4 ...
##  $ smoothness_se          : num  0.0064 0.00522 0.00615 0.00911 0.01149 ...
##  $ compactness_se         : num  0.049 0.0131 0.0401 0.0746 0.0246 ...
##  $ concavity_se           : num  0.0537 0.0186 0.0383 0.0566 0.0569 ...
##  $ concave.points_se      : num  0.0159 0.0134 0.0206 0.0187 0.0188 ...
##  $ symmetry_se            : num  0.03 0.0139 0.0225 0.0596 0.0176 ...
##  $ fractal_dimension_se   : num  0.00619 0.00353 0.00457 0.00921 0.00511 ...
##  $ radius_worst           : num  25.4 25 23.6 14.9 22.5 ...
##  $ texture_worst          : num  17.3 23.4 25.5 26.5 16.7 ...
##  $ perimeter_worst        : num  184.6 158.8 152.5 98.9 152.2 ...
##  $ area_worst             : num  2019 1956 1709 568 1575 ...
##  $ smoothness_worst       : num  0.162 0.124 0.144 0.21 0.137 ...
##  $ compactness_worst      : num  0.666 0.187 0.424 0.866 0.205 ...
##  $ concavity_worst        : num  0.712 0.242 0.45 0.687 0.4 ...
##  $ concave.points_worst   : num  0.265 0.186 0.243 0.258 0.163 ...
##  $ symmetry_worst         : num  0.46 0.275 0.361 0.664 0.236 ...
##  $ fractal_dimension_worst: num  0.1189 0.089 0.0876 0.173 0.0768 ...
##  $ X                      : logi  NA NA NA NA NA NA ...

From the result above, weknow the following: 1. The first column is id. it is unique and unnecassary for prediction. so, it should be removed. 2. The second column is diagnosis. this should be a class variable, Currently the type is char and it should be converted to factor 3. The last column is x. All the values are NA. So, it should be removed.

bcw_df$id <- NULL
bcw_df$X <- NULL

# change to factor for target variabel
bcw_df$diagnosis <- as.factor(bcw_df$diagnosis)

2.1 Univariate Data Analysis

Analysis satu variable. contoh: boxplot, histogram, piechart

library(ggplot2)

ggplot(data=bcw_df, aes(x = diagnosis)) +
  geom_bar()

Distribution of Radius Mean variable in boxplot

ggplot(data = bcw_df, aes(y=radius_mean)) +
  geom_boxplot() +
  labs(title = "Breast Cancer Wisconsin Data", y="Radius Mean")

Distribution of Radius Mean variable in histogram

ggplot(data = bcw_df, aes(x=radius_mean)) + geom_histogram()
## `stat_bin()` using `bins = 30`. Pick better value with `binwidth`.

library(gridExtra)
p1 <- ggplot(data = bcw_df, aes(x=diagnosis)) + geom_bar()
p2 <- ggplot(data = bcw_df, aes(y=radius_mean)) +
  geom_boxplot()
p3 <- ggplot(data = bcw_df, aes(x=radius_mean)) + geom_histogram()

grid.arrange(p1,p2,p3, nrow = 2, ncol = 3)
## `stat_bin()` using `bins = 30`. Pick better value with `binwidth`.

2.2 Bivariate Data Analysis

Analysis of two variables, Distribution of radius mean variable based on diagnosis.

ggplot(data=bcw_df, aes(x=diagnosis, y=radius_mean)) +
  geom_boxplot() +
  geom_jitter(alpha = 0.3,
              color = "blue",
              width = 0.2) +
  labs(title = "Breast Cancer Wisconsin Data", y="Radius Mean")

ggplot(data = bcw_df, aes(x=radius_mean, fill = diagnosis)) + geom_density(alpha = .3)

Observations based on radius mean and texture mean variables. Each point is a single observation. the color and shape of the observations are based on diagnosis (benign and malignant)

ggplot(data=bcw_df, aes(x=radius_mean, y=texture_mean,
                        shape=diagnosis, color=diagnosis)) +
  geom_point() +
  labs(title = "Breast Cancer Wisconsin Data", x="Radius Mean", y="Texture Mean")

In general, benign has lower radius mean and texture mean than malignant. However, these two variables are not enough two separate the classes

2.3 Multivariate Data Analysis

There are three types of measurements: mean, standard error (se), and worst (mean of the three largest values). Each measurement has 10 variables so the total is 30 variables. We want to compute and visualize correlation coefficient of each measurement.

Visualize person’s Correlation Coefficient for *mean variables

# install.packages("corrgram")
library(corrgram)

corrgram(bcw_df[2:11], order = TRUE,
         upper.panel = panel.pie)

Visualize person’s Correlation Coefficient for *se variables

corrgram(bcw_df[12:21], order = TRUE,
         upper.panel = panel.pie)

Visualize person’s Correlation Coefficient for *worst variables

corrgram(bcw_df[22:31], order = TRUE,
         upper.panel = panel.pie)

We can also see area, radius, and perimeter are co-linear. So, we need to remove two of them:

We can also see compactness, concavity, and concave.points are co-linear. So, we need to remove two of them: compactness and concave.points.

3. Data Processing

3.1 Feature Selection

Remove *_worst variables, based on discission with domain expert, the alll variables with ending worst should be removed.

bcw_df2 <- bcw_df[1:21]

Remove area, perimeter, compactness, concavity

bcw_df2$area_mean <- NULL
bcw_df2$perimeter_mean <- NULL
bcw_df2$compactness_mean <- NULL
bcw_df2$concavity_mean <- NULL

bcw_df2$area_se <- NULL
bcw_df2$perimeter_se <- NULL
bcw_df2$compactness_se <- NULL
bcw_df2$concavity_se <- NULL

dim(bcw_df2)
## [1] 569  13

3.2 Remove Outlier

3.3 Feature Scaling

3.4 PCA

pr.out <- prcomp(bcw_df[2:31], scale. = TRUE)
pr.out$x
##                 PC1           PC2          PC3          PC4           PC5
##   [1,]  -9.18475521  -1.946870030 -1.122178766  3.630536408  1.1940594778
##   [2,]  -2.38570263   3.764859063 -0.528827374  1.117280773 -0.6212283647
##   [3,]  -5.72885549   1.074228589 -0.551262540  0.911280840  0.1769302185
##   [4,]  -7.11669126 -10.266555635 -3.229947535  0.152412923  2.9582754313
##   [5,]  -3.93184247   1.946358977  1.388544953  2.938054169 -0.5462667446
##   [6,]  -2.37815462  -3.946456430 -2.932296681  0.940209586  1.0551135428
##   [7,]  -2.23691506   2.687666414 -1.638471247  0.149208600 -0.0403240371
##   [8,]  -2.14141428  -2.338186649 -0.871180715 -0.126931171  1.4261817833
##   [9,]  -3.17213315  -3.388831138 -3.117243065 -0.600768440  1.5209521144
##  [10,]  -6.34616284  -7.720380945 -4.338098744 -3.372234369 -1.7087596141
##  [11,]   0.80970132   2.656937673 -0.488400053 -1.671096176 -0.2755690974
##  [12,]  -2.64876984  -0.066509405 -1.525113359  0.051216497 -0.3316592904
##  [13,]  -8.17783882  -2.698602007  5.725193241 -1.111278747 -1.0425531111
##  [14,]  -0.34182514   0.967428026  1.715661982 -0.594479872 -0.4675990720
##  [15,]  -4.33856172  -4.856809832 -2.813639832 -1.453278303 -1.2889287269
##  [16,]  -4.07207318  -2.974443983 -3.122526655 -2.455909915  0.4079831402
##  [17,]  -0.22985277   1.563382114 -0.801813642 -0.650010973  0.4942761390
##  [18,]  -4.41412695  -1.417423150 -2.268323145 -0.186108659  1.4226094459
##  [19,]  -4.94435304   4.110716528 -0.314472408 -0.088128974  0.0566653163
##  [20,]   1.23597583   0.188049490 -0.592761930  1.594942716  0.4417655273
##  [21,]   1.57677384  -0.572304625 -1.799863016  1.124286473  0.3949222435
##  [22,]   3.55420904  -1.661487969  0.450790799  2.071941593  0.4903150736
##  [23,]  -4.72904972  -3.302058265 -1.465247427  2.039355666  0.0261970715
##  [24,]  -4.20482441   5.123858059 -0.751740573 -0.861951843  0.4705538779
##  [25,]  -4.94528075   1.542395143 -1.711687827  0.046718059  1.7377012054
##  [26,]  -7.09232236  -2.016835734 -0.028984132  2.585675482  2.0375470912
##  [27,]  -3.50717666  -2.169715994 -3.891122637 -1.294620549  0.0681580703
##  [28,]  -3.06136021   1.874902631  2.579478032  0.128371462  0.1165625639
##  [29,]  -4.00374127  -0.536769860 -2.759197831 -1.896718595  0.5252107652
##  [30,]  -1.71380176   1.522365502  0.146058578  1.909706071 -0.5356519265
##  [31,]  -6.05411853   0.756511800 -0.348932376 -1.063281958  0.7454493340
##  [32,]  -2.89968469  -4.001774373 -2.998823809 -0.325030387  0.8546038749
##  [33,]  -4.55077848  -0.337239419 -0.753637681 -0.699714306  1.5471839770
##  [34,]  -4.98621538   1.131593223 -2.575118337 -1.216191663 -0.6693259394
##  [35,]  -2.98271631  -0.757756497 -3.490690279  0.054212589 -0.1669530505
##  [36,]  -2.76393718   0.354044421 -1.895295337 -0.533786198  0.8832432812
##  [37,]  -1.29505925  -0.912393466 -1.574383382 -1.042249570 -0.4143571251
##  [38,]   3.74601730   1.412230504  1.730784885 -0.564945456 -0.0802687991
##  [39,]   0.99719148   3.348346731  4.301788720 -0.560716245  0.4639645611
##  [40,]  -0.76459136  -0.885464837 -2.702540362 -0.274538185 -0.8097169787
##  [41,]   2.14906252   1.922300194 -1.179446370 -1.112219391 -0.4480774771
##  [42,]   0.09324934  -2.258764532 -1.903051997 -1.441039161  1.7038647386
##  [43,]  -9.08001023  -2.016898441  2.139343894 -1.068304028 -0.7972299505
##  [44,]  -0.98958304  -0.984064148 -2.308702241 -0.276582144  0.6399478981
##  [45,]   0.29328849   0.136978564 -3.299029123 -1.008898141  0.0224910920
##  [46,]  -5.37620991   0.134758404 -1.677366657  1.506369463 -0.1518645822
##  [47,]   4.57790860  -1.482915508  0.042037623  0.295968708  0.7132249498
##  [48,]  -1.69851237  -2.350203862 -3.075383081 -0.065962912  1.0555376469
##  [49,]   2.13456708  -0.095745364 -1.491099878  1.120077655  0.0679774156
##  [50,]   1.56610099   1.207370855 -0.368834570 -1.474331566 -0.1725985690
##  [51,]   3.53979091   1.281368110  1.017315805 -0.607621596  0.2194428358
##  [52,]   3.15503795   1.687473796 -0.495857416  0.193841543 -1.4386516886
##  [53,]   3.44745515   0.497780720 -0.152383875  0.574980496  0.0522688899
##  [54,]  -3.29964761   1.129943574  0.825666100  0.981853085  1.1942122234
##  [55,]   0.67402621   2.114549137 -1.394992302 -1.042221635 -0.2416042153
##  [56,]   2.85564577  -0.152588874  0.428557855  0.482635650  1.5092086632
##  [57,]  -4.64465207   2.308301508 -0.728168145  0.639379104  1.1573061797
##  [58,]  -2.17494916  -0.971261438 -1.942179421 -0.736670095  0.3954358798
##  [59,]   3.71818738   1.786070097  1.278807604  0.115464169  0.5258196576
##  [60,]   4.13232693  -2.401679261 -1.241865694  2.046545722  1.1646276518
##  [61,]   2.38373822  -2.755233814  1.213018303  1.792911568  3.3352233901
##  [62,]   2.57661610  -3.135912650  1.399049169 -0.763194998  2.7816479152
##  [63,]  -4.75492832  -3.009032875 -0.166094576 -0.605295233 -1.1406976712
##  [64,]   2.31209785  -3.265116721  2.793766025  0.565229094  0.3814984103
##  [65,]  -1.69012080  -1.539322116 -1.798262954 -1.389367072  1.2116088977
##  [66,]  -1.81071217  -0.722104815 -1.464960560 -1.197676214  1.4267861675
##  [67,]   2.78347559  -2.308617372  0.472309720 -1.605747397  1.6114402596
##  [68,]   3.51555502   0.657730736  0.590855071 -0.010793189 -0.0205709988
##  [69,]  -4.32619605  -9.194435552  1.491650337  0.319666023 -4.7240139158
##  [70,]   3.25841241   0.937013647  0.204949679  1.089113223  0.4599452518
##  [71,]  -2.70221851   4.433240985  0.307075192  0.488263229 -0.3721675732
##  [72,]   0.30758513  -7.381317396  3.815728542  2.131680166 -2.7083196796
##  [73,]  -5.49886689  -0.937500513 -2.208188675 -1.522456429 -0.9240784393
##  [74,]   0.36139121  -0.119633821 -2.039161544  1.057953093 -0.7564437850
##  [75,]   2.62766457   0.696696349 -0.583428281  0.337884296 -0.4671344130
##  [76,]  -1.42691206   1.965372092  1.110961327  0.752248984  0.5394071070
##  [77,]   0.83378424  -1.963876860  0.789737653  3.434609101  2.3524809639
##  [78,]  -6.22541880  -0.919260690  0.089748341  2.536926544 -0.0620812262
##  [79,] -11.65845644  -4.744442593  2.004115633  0.318768543  3.3883795562
##  [80,]   2.01980045   0.254675746 -0.647302452  0.059199217  0.0547996477
##  [81,]   1.63694460  -1.714440587  0.433824539 -1.526622964  1.7678261507
##  [82,]  -1.16643527  -2.512305286 -1.904043397  0.637750373 -0.2359734956
##  [83,] -10.75977535   2.255997858  0.038801648 -0.389043228 -1.1862447821
##  [84,]  -5.03038488  -0.773728357  2.679979922 -1.665039071  0.3113456414
##  [85,]   2.17255269  -0.496441169 -0.948257444  0.207037052  0.8845677371
##  [86,]  -3.28534463   1.666770480  0.146802675  0.437108401  1.3673667927
##  [87,]  -0.60707378  -0.162071919  1.635935419 -1.113531850  0.5403198078
##  [88,]  -3.58041324   2.204721916 -1.703037100 -0.800589442 -0.3650009185
##  [89,]   0.93333687  -0.926885919 -0.040128345 -1.352209082 -0.0648850467
##  [90,]  -1.25849730  -1.014684255 -0.080521995  2.049531496 -0.1373994614
##  [91,]   1.58686770   1.618232954  0.309726682 -1.091038889 -0.0537268234
##  [92,]  -0.25227559   0.530884425  0.588809736 -0.110441165 -0.4283042881
##  [93,]   2.84492835   2.891103732  0.527524677  0.598290300 -1.4344348070
##  [94,]   1.96322268   0.964308498 -0.081136715 -0.093998029  0.5495403920
##  [95,]  -2.77342525  -0.557509977 -0.605238702  0.499390598 -0.4994662006
##  [96,]  -4.39236314   2.121640892  0.579000549 -0.776729960  0.3035669597
##  [97,]   2.58980407  -0.213446120  1.034701089  0.661423462  0.5402889624
##  [98,]   3.90090576  -1.189020421  1.550616806 -0.934952821  0.7074978792
##  [99,]   2.81575365  -0.367560567 -1.350247556  1.736886645 -0.2840715251
## [100,]  -0.61573908  -0.638349988 -0.199743121 -1.096533937 -0.1185853914
## [101,]   0.43247968   1.390820523 -0.082646762 -1.933578565  0.0344302397
## [102,]   4.55102442  -3.525683788 -0.215074716  1.090925794  2.7559240651
## [103,]   3.44515217   1.423370040 -0.088646005 -1.709223842  0.1065229834
## [104,]   2.11410008  -1.847747782 -0.556184595 -0.463948150  0.4744968363
## [105,]   2.68898618  -1.418813334  0.968298772 -0.002857011  1.2554137475
## [106,]  -3.21109134  -4.043198634 -2.712997305  1.327457319  0.2214783192
## [107,]   0.74861266  -1.796058175 -0.567866143 -0.560006237  0.9322757208
## [108,]   3.15622889   1.034838878 -1.489373670 -0.592646911 -0.5136339075
## [109,] -13.04464395  -0.980650357  0.598286247  1.471636087  0.5993856696
## [110,]   2.22672053  -0.666823902 -1.090600727 -1.077353762  0.2988661489
## [111,]   2.49063954  -2.596401708  1.668257671  0.632929090  1.1557305724
## [112,]   0.10325957  -2.278139015  2.107708229 -0.351536677 -0.6219347413
## [113,]  -3.58813694  -3.922881433  2.045207163 -0.231562584 -5.4604591892
## [114,]   1.34776279  -3.553098748  1.730668471 -0.046949434  0.3449474850
## [115,]   2.50791098  -3.248461200 -1.686140767  1.188915291  0.4551865326
## [116,]   2.04423086  -0.304616836 -0.533369397 -0.489411120  0.0678524055
## [117,]   2.09522559  -3.663872062  3.629007335  1.538433194 -2.2345636748
## [118,]  -3.10779316  -1.568009873 -2.611638159  0.617924024  1.1807403791
## [119,]  -4.95236801  -2.382749650 -1.933405900 -0.610304229  0.1480794337
## [120,]  -0.85026612   2.304707468  0.566963050 -0.043586897  2.0922055990
## [121,]   2.96339173  -0.371179883 -2.064716427  2.070684315 -0.1628943517
## [122,]  -3.33120209   1.324392029  0.727373652  1.002316780  0.9328861016
## [123,] -12.88327621  -2.314585873  6.323133317  1.940496559  3.1574494112
## [124,]   0.77006610   0.064052860 -1.133411514  2.508256103 -0.0202192366
## [125,]   2.20057925   0.734958544  0.266845303 -0.037586447 -2.9314571580
## [126,]   3.14064881   1.875758557 -0.669779705  0.303065257 -0.4077106627
## [127,]   0.63831885   0.910564828 -2.140840449 -2.139033534  0.4287624850
## [128,]  -1.91744627   3.534971966  1.253821297  0.335703696 -0.5885511025
## [129,]  -1.40762980  -1.303782215  0.640864876  1.885297508  0.0362201276
## [130,]  -4.63960895   1.480714297 -1.169651383 -1.217534223 -0.1779160105
## [131,]   1.87581684  -1.421979452 -1.069870821  1.707830258  0.8837714798
## [132,]  -1.43081046   1.048681220 -1.260901861  0.532720319  0.6261456617
## [133,]  -1.35143790   1.153126842 -1.208729712 -0.827378497  0.9859398192
## [134,]   0.70849143   1.566853657 -0.669405084  1.685780647 -0.3390165106
## [135,]  -2.16950708   2.823776101 -0.561613332 -0.660250673  0.4745525764
## [136,]   1.97510247   0.419018755 -0.380240597 -1.737931013  0.3083668329
## [137,]   2.59850310   0.481911436  1.870726668 -0.437633248 -0.0160686443
## [138,]   3.25514318   0.417953651 -0.691197447  0.659273518 -0.1214593563
## [139,]  -3.77870160  -0.859625218  3.667773435  2.046019895  2.1818702714
## [140,]   1.99028348  -1.328186508  1.134246527  2.044634146  0.2519061287
## [141,]   5.01059989  -0.574194748 -0.841697543  2.167755281  0.8812268193
## [142,]  -1.34383800   1.273650278  0.555354894  0.574366142  0.4704353120
## [143,]   2.45380972  -0.897665441  0.352823033 -0.367668079  1.1033160270
## [144,]   1.83566648   0.090946742 -1.444010288  0.671957291  0.1360791853
## [145,]   4.34266862   0.892786708  0.638694049  0.425252734 -0.9556015217
## [146,]   0.73216868  -3.698927716  0.657926113  2.234161633  0.3361716375
## [147,]  -2.39788795  -4.833735642 -1.027253164  0.342615376  2.3897699977
## [148,]  -0.39275308  -1.082115915  2.245629588 -0.461452569 -1.6901413981
## [149,]   0.41196533   0.389288784 -1.044851048  1.365044596 -0.8627479982
## [150,]   3.04724369   2.235817239 -0.469040276  0.182614048 -1.5744606816
## [151,]   1.44129554  -0.305601552  0.551062974  0.355761009  2.7005428427
## [152,]  -0.08311297  -7.144073768 -0.059957215 -1.801496676 -0.7374637239
## [153,]  -7.08707084 -12.562140869  7.352238887  1.224264329 -7.4838486945
## [154,]   3.74011364  -0.250281306 -0.097297641  1.930448497  1.0426741051
## [155,]   0.96832079  -0.944113582 -0.890028129  1.095568323  0.6129630899
## [156,]   2.41659356  -0.005547532 -0.797678511 -0.070829748  0.0772419138
## [157,]  -4.09718264   0.378470806  1.445046044  0.701751100 -0.0006644087
## [158,]   0.75094226   3.067949187  1.447907672 -0.952587697 -0.8911446262
## [159,]   3.65143365   0.674055644 -0.906188637  1.509832817 -0.2935538042
## [160,]   4.67609710   1.102886823 -0.257081973  1.245379911 -0.4142538767
## [161,]   0.59725624  -1.784081072  1.480433343 -0.177715866  1.5878294278
## [162,]  -3.38435289   2.908477953  3.004594027  2.825801426 -0.5078995524
## [163,]  -6.14447970   2.015878994 -1.564766888  0.970791871  0.3360742118
## [164,]   1.32386648  -1.468002337  0.847675513 -1.141761837  0.0477797028
## [165,]  -5.48932277   4.162167037 -0.600732185  0.149568094 -0.6250164993
## [166,]   2.99476813   2.736453261 -0.161042080 -0.412806573 -0.4051896121
## [167,]   4.38287625  -0.006866240 -0.947274735  2.795545994 -0.4453390247
## [168,]  -1.21256768   2.037246395  0.979834026  0.238756035 -0.0856932721
## [169,]  -5.06520424   1.783582969  1.172615291 -0.693122956 -0.6480853131
## [170,]   1.97596280   1.841159394 -0.277115927  0.549266608  0.2067144089
## [171,]   2.51266554  -0.114151857 -0.496186180  2.352277364  0.6887689035
## [172,]   0.94665494   1.683272444 -0.350877607 -0.576703303  0.3412418770
## [173,]  -2.81688978  -1.263990953 -2.151251366  2.706077979  0.0400092558
## [174,]   3.48092345  -1.618268077  2.673117328  1.252511728  0.5984548400
## [175,]   4.65463399   0.222718846  1.557987797  0.510643007  1.8952731945
## [176,]   5.34691339  -1.025855214  0.324700222  1.367479190  0.9178537547
## [177,]  -1.16986842  -7.008319996  4.268106508 -0.332347396 -2.9068870248
## [178,]  -2.95370292  -0.705800822 -1.041419103 -0.521690540 -1.4123928506
## [179,]   4.97132782   3.383227983  0.439451738 -1.576183104 -1.0328868993
## [180,]   4.06045289   1.245070643  0.573972801  1.703893823 -0.6153230400
## [181,]  -9.50430706   5.598558052 -0.636679193  0.224024081  0.4061861282
## [182,]  -8.99924714  -0.580520281 -3.131959404 -0.861511555 -0.0456818494
## [183,]  -0.75821134   1.607118481 -1.513763762 -1.075114038  0.0491913464
## [184,]   2.65702172  -0.539461132  1.705514033  1.200694830 -2.3526717446
## [185,]   0.38967611   0.988372689 -2.582896564 -0.783837500 -0.7336657053
## [186,]   3.88564657  -0.815354285  1.014824328  0.824193256  2.1316971080
## [187,]  -0.36455538   3.571318842 -2.222023387  0.222971846 -0.7778465452
## [188,]   2.83339783   0.398379162 -0.347139642  0.812532578  0.0392461561
## [189,]   3.30737348  -0.155604280  0.541002917 -0.512033374  1.7863073596
## [190,]   3.35435293   1.102762109  0.151956099  0.827459950 -0.7336137377
## [191,]  -6.51738201  -8.004126824 -0.326136731 -2.769361777 -1.5975261925
## [192,]   1.71622508   0.542688019  3.295475582 -0.087253972 -0.0840995519
## [193,]   5.56084294   0.477427493  4.123834207 -2.350422636  1.0515357688
## [194,]  -1.77809695  -2.774146213 -0.941934046 -3.071649469  0.6945219915
## [195,]  -2.60918908  -1.560049030 -0.217995141 -0.492342056 -1.1034164923
## [196,]   2.81656023   0.969257722 -0.382255094  0.463382873 -0.5513017565
## [197,]  -2.49624245  -2.276479790  1.318318594 -1.179800454  1.8980601601
## [198,]  -1.27590451   2.441111044  2.464148795 -0.129776372 -2.1534113490
## [199,]  -3.47014398   2.275846405 -1.237595112 -1.112162383 -1.0083717623
## [200,]  -1.25557034  -0.382057094 -3.834946034 -0.716289870  0.6505837048
## [201,]   1.47213604  -0.116787496 -0.214479145 -0.490377374  0.7132142476
## [202,]  -1.64801062   2.100442902 -0.974414210  0.187878371 -0.9160201700
## [203,]  -9.02864522   0.654596849  0.221085545 -0.764058327 -0.5644000271
## [204,]  -4.55058603  -3.083925626 -2.268408346 -2.189192919  3.4583122917
## [205,]   0.78050321  -0.652275325 -0.643091145  0.214279700  0.4372951306
## [206,]   0.22289648   0.701204504 -2.268765765  0.997753580 -0.6459195774
## [207,]   3.45185811  -1.305789765 -0.029238791  0.330213202  1.8602747487
## [208,]  -0.44615183   2.785257008  0.443991604  0.471613571  0.5295236919
## [209,]  -0.31416180  -2.075734301 -2.081480386 -1.067600421  0.2176779819
## [210,]   2.05738166   2.470613908 -1.460433790  1.866439637 -1.8369468233
## [211,]  -4.80474158   3.026440019  2.741606351  0.283114502 -0.1937940455
## [212,]   2.99607430   0.396429212 -0.595941573 -0.207862040 -0.5678601226
## [213,] -12.27421974   7.536778599 10.103533703  5.189703614  3.8491201120
## [214,]  -3.36923202  -2.585550416  7.085840019 -0.367171665 -2.7681374358
## [215,]  -2.50656080  -2.612349885  0.206198902 -1.893080135  2.1228977028
## [216,]  -1.31690973  -2.152585453 -1.785061911 -0.010160725 -0.1670054272
## [217,]   0.38841453  -2.274796314  0.626780574 -0.429349217 -0.1192752256
## [218,]   2.75450931  -1.085879226  1.705737291 -0.516377016 -0.8063132292
## [219,]  -4.93923501   2.845820436  0.913075404  0.334889341  0.4829010175
## [220,]  -4.29429880   4.662172958 -0.006834994 -3.650173128 -0.1785458275
## [221,]   2.37141521   0.732757814 -1.524685925  1.851700285 -1.1820779548
## [222,]   0.96634003  -0.438052741 -1.446423567  1.988611655  0.0938834761
## [223,]   2.97318270  -1.809381711 -0.223238842  0.391290904  1.5280262811
## [224,]  -1.80166175  -0.166314618 -2.626288708 -0.643175553  0.5214235661
## [225,]   2.47618073   1.417329346 -0.316254972  0.328213945 -0.6614306092
## [226,]   0.82531310   1.249148354  0.267725157  2.308595141  1.0139214702
## [227,]   3.89127342  -0.538097276 -0.880783727  1.037886765  0.8083176466
## [228,]   0.38923560   0.613875324 -1.351679911  1.174159176 -1.7883197584
## [229,]   1.45604019   0.201549415 -1.097912687 -2.004011649 -1.4772623926
## [230,]  -2.75314552  -3.462726769 -2.471875866 -1.007392449 -0.1549996143
## [231,]  -3.25439115   0.125090426 -2.893551435  0.748931137  0.3525453547
## [232,]   4.01560693   1.353056834 -0.360155815 -2.633480577 -0.7345986421
## [233,]   3.67318128   1.290493562  0.424237023 -4.597664394  0.7402578603
## [234,]  -3.31340866   3.935689268 -0.205273062 -2.116361469 -0.9691280654
## [235,]   4.03305870  -1.161524089  0.189581014  0.939690169  0.5651016963
## [236,]   2.33218128   1.347793816  0.232482459 -1.211847619 -0.0515295475
## [237,]  -8.39645911   4.150252991  0.046927784 -0.551357625  0.2878270868
## [238,]  -2.64524110   3.947699392  1.370675284  0.207636553 -1.4038189712
## [239,]   0.68116951   1.134992457  1.232581929 -3.861102774 -1.4270964368
## [240,]  -3.34735048   2.152675899 -1.107968825 -4.345184373 -0.0623295495
## [241,]   2.22576208   1.213931555 -0.192244621  1.469984705 -0.0196978073
## [242,]   4.47364832   1.739598699 -0.887426246  0.763980319 -0.6046080177
## [243,]  -1.32145867  -4.785266054 -0.661952674 -1.020298051 -2.1481343740
## [244,]   1.84846341   1.582735509  1.262806090 -0.801397452 -0.7107861777
## [245,]  -3.79222888   1.025330459  0.897845626 -0.759791922  0.7571812276
## [246,]   2.27931254  -2.075859442  2.428512195 -1.185017124  2.8564899050
## [247,]   3.22593164   1.171043084  0.264431658 -1.002062865 -0.8936812738
## [248,]  -1.02499890  -2.359186109 -1.615464155  1.144955805 -4.1408350383
## [249,]   2.58028546  -0.728572047 -0.547660903 -2.330028998  1.8336515859
## [250,]   2.48369783  -0.460191483 -0.598393817  0.997839640  0.4299455562
## [251,]  -7.13756174   2.073018195  1.087430513  0.715703759 -0.8191801992
## [252,]   3.02981522   0.648897838  0.310409540  0.579772365  0.7322406058
## [253,]  -7.07878207  -0.527758800 -1.278861780  0.650990489 -1.8521950854
## [254,]  -1.31294375   1.773865017 -1.671161321  0.694009370 -0.1127114795
## [255,]  -3.70838653   2.805008998 -1.754649703  0.903310417  0.0709235923
## [256,]  -0.46007427  -0.393819769 -1.003815294  1.074442849  0.4271589571
## [257,]  -6.38703001   1.821491443  0.479427881 -1.694969593 -0.5561879657
## [258,]  -5.25092469  -3.891107226 -0.833120389  1.680122512  0.7836374535
## [259,]  -8.72618338  -3.276993966  2.901146761 -0.276944482  1.0609133753
## [260,]  -3.68807276  -1.064709236 -3.512498419 -4.769000799  0.8017786584
## [261,]  -3.37528098   3.368264175 -1.765224543 -2.076130195  0.5972560049
## [262,]   0.83947101   3.497008034  0.182323228 -1.241480335  0.1084218681
## [263,]  -3.28148526   0.989802279  2.552140777 -0.122718992 -0.3505294554
## [264,]   1.90709089   3.119201237 -1.062121558 -1.061133233 -0.9564549675
## [265,]  -1.61336234   2.472397898 -1.989384336 -0.378757895  0.4428590571
## [266,]  -6.61390681   5.997998811  0.988507976 -2.884219766  1.6938934564
## [267,]   1.46338831  -1.685149061  1.168877382  0.325375950  0.4644646263
## [268,]   2.01038350   1.102516460  1.336847795 -1.614259260 -0.6911126965
## [269,]   2.28233204  -0.009485293 -0.450043551  0.295519714  0.8031608330
## [270,]   0.73909276  -3.149749158  1.468565664 -0.314616789 -0.9468561582
## [271,]   4.50260070   3.166486414 -0.187896260  0.390816184 -1.3839888843
## [272,]   3.15597737  -0.409941090 -1.107842420  1.969885542  0.0585356134
## [273,]  -7.66940121   3.072602737  1.480656591  0.551916238 -0.8854262609
## [274,]   3.63593673  -1.588189625  0.715650110  0.669795890  1.5759444757
## [275,]  -0.33704893   3.141609173 -0.115619749 -1.813699425 -0.0352621513
## [276,]   1.27546111  -0.848306563  3.067369195  1.165472001  2.6757698121
## [277,]   4.34219338   0.321694999  0.388133185  1.106173921  1.5020111044
## [278,]  -0.01741547   3.456302110  0.306650981  0.475151814 -0.4003842967
## [279,]   3.48935577   2.631766723 -0.072124181 -0.307707020 -0.5245541387
## [280,]   1.86490793   0.901271186 -0.870402828  1.027910020  0.2316732520
## [281,]  -4.95590744   1.339944038 -1.455772409 -1.466907423  0.6119216765
## [282,]   2.46855062   0.137904923  1.793307382  1.546266616  0.6967490495
## [283,]  -3.78173258   1.900235409 -1.742708503  0.391939754  0.3389814297
## [284,]  -2.63493731  -0.576647607 -1.992946242  0.272309546 -1.1957159307
## [285,]   1.37147827  -0.005800358  1.547927203  0.583925361 -3.0022368265
## [286,]   4.13524399   1.375298123  0.877276691 -0.059803630  0.5970712749
## [287,]   0.68633639  -1.693519506  1.025310679 -0.874708540 -2.1727638053
## [288,]   4.30833870   1.976746804 -0.251085558  1.573526614 -1.9816674884
## [289,]  -0.40295486  -3.720160654  4.582436940  0.215721385 -0.8070907499
## [290,]   3.00096526  -0.353848878  1.232930128 -0.716826045  1.3114083326
## [291,]  -3.13125303  -4.269702670  5.861122345  0.596058607 -4.1973346842
## [292,]   0.41746954   0.807865734 -1.092330348 -0.089650892 -0.2568431865
## [293,]   1.41897459  -1.392752638 -0.836251021  1.104473313  0.3640802623
## [294,]   2.86806475   0.268408338 -0.468574962 -0.245287741  0.5574288140
## [295,]   3.36288672   0.806890637 -0.806369895  1.662223414 -0.0505417655
## [296,]   3.31208587   1.440908382 -0.583119519  1.783361666  0.0192555651
## [297,]   4.76551701   0.542484530  0.893082182  1.729539559 -1.0008319932
## [298,]   2.38378528   0.823391074  1.982219343  0.055206875  0.5052838506
## [299,]   2.78464581   2.530807159 -0.883257225 -0.259446372 -1.6463839898
## [300,]   3.39085817  -0.753301131  1.770235939 -0.276430081  1.0849483019
## [301,]  -6.58444233   1.483557076  0.361022239  1.187401386  0.1208047145
## [302,]   1.45405111  -0.591422478  1.145332613  0.078947827 -1.0867825344
## [303,]  -7.17661843  -0.055097580  2.011148288  0.082703332  0.6651964595
## [304,]   3.57568917  -0.890799182  0.261257526 -0.253872371  0.5990662990
## [305,]   3.05434514   0.179055836  0.621226832  0.261168580 -0.8959467593
## [306,]   3.07173303   0.305789373  1.258146621 -2.206685025  0.6058786167
## [307,]   3.85015201   1.523386003 -1.143503482  0.814334011 -0.4926180820
## [308,]   5.38551771  -0.555766489  0.559577694  0.471440565  0.3994468273
## [309,]   4.65358767   3.062692587 -0.075942289  1.507190163 -1.2716964644
## [310,]   4.02400169   2.540671520  0.352906609  1.513056174 -0.6669118526
## [311,]   3.34487880   0.068502773 -0.269955756 -0.627084568  1.1246979202
## [312,]   3.29694105   3.135950089  0.148761476  0.741837997 -0.3941040424
## [313,]   2.13452598   0.004388987 -0.055090483  1.786540911 -1.2993021931
## [314,]   4.03446724   0.240486452 -1.326959165  2.438086999 -0.2771454326
## [315,]   3.76210430  -4.394333943  3.946735131 -0.306998155  4.7854456445
## [316,]   4.86695697   2.337158334 -0.168146877  0.694278950 -0.8202171408
## [317,]   4.74307511   1.796820963  0.169570993  1.550246788 -0.5346670358
## [318,]  -1.89365006   2.390134936 -1.675017462  0.711402276 -0.3830648490
## [319,]  -1.57154834  -6.503377021  2.165253786  0.030049446 -1.0524851013
## [320,]   4.02308037   1.400973753  3.183698584  0.019535088 -0.1794905224
## [321,]   1.29372783  -3.467757378  1.108552569  0.766005357 -0.2103251163
## [322,]  -1.83322742   4.317723823  0.316406925  0.996312898 -0.2544647520
## [323,]   1.80878902  -0.395858988 -1.229252510  1.275533990 -0.0070705863
## [324,]  -7.23012357   0.035670411 -2.838568987  0.038607870  2.4525784786
## [325,]   3.14288478   0.741873771 -0.861593396  0.754499772 -0.2998611546
## [326,]   2.88472980   0.464323069 -0.475325102  0.761631787  0.8524662824
## [327,]   3.14688506   1.769691255 -0.035802185  1.505914596 -0.3529936101
## [328,]   4.62431058   1.834004631  0.064174505  0.094110332 -0.7997554706
## [329,]  -2.24853190   0.348229535 -1.063814825 -0.231555660  1.0036176419
## [330,]  -2.10594822  -1.120987593  1.773597643  0.262444379  0.9599662498
## [331,]  -1.78437991   0.268984957 -1.721001037  1.031779098 -1.1840685475
## [332,]   0.52723271  -1.264758769 -0.919631937  0.429094010 -0.5602900988
## [333,]   3.21067592  -1.102473082  1.610564041 -0.486005834  3.4562087554
## [334,]   4.38256677   0.760434627 -0.400245248  0.586341023  0.3762481427
## [335,]   3.80666840   0.909118626  0.442778081 -0.949587668  0.3513268837
## [336,]  -3.31675558   1.575666422  1.359532256 -0.693532863  0.9081313503
## [337,]   2.39117199  -0.989160421 -0.756844005  1.553615921 -1.4301998125
## [338,]  -4.67605183   0.967741443 -0.291016193 -1.073327945  0.1324405011
## [339,]   3.06499827  -1.134839030  0.374293207 -0.626302932  1.4424249065
## [340,]  -7.34675421   5.238014242  0.316677175  0.431659928  0.7054132905
## [341,]  -0.29505357  -0.226735533 -1.088458865  0.946589841 -0.7284538257
## [342,]   1.93726491  -2.542750760 -1.000543159  0.025717223 -1.2050388549
## [343,]   2.07535283  -1.804931340 -1.166053416  1.141225718  0.4132078419
## [344,]  -4.97078859   1.331400687  0.870211875 -1.290995242  0.9611232170
## [345,]   2.17500311  -0.958068260 -0.234058923  1.852842435  1.4804780811
## [346,]   2.42941383  -3.444173357  3.453905770  0.493225969  1.0448376978
## [347,]   3.36500493   0.562434015 -0.192404359 -0.569877839  0.3514194212
## [348,]   1.20553704   1.315886497 -0.929922572  1.703291193 -0.7180879050
## [349,]   3.32315522  -0.474753848 -0.897496041  0.812772706  0.5848648524
## [350,]   1.92709976  -1.460184989 -0.100554033  1.819163615  1.9342391900
## [351,]   4.03828183   1.355724562  0.537868401  0.833178809 -0.1785899127
## [352,]  -6.17684877  -5.103514894  0.520682438  0.939912167  0.6059916654
## [353,] -10.92468559   3.699998472 -0.890910165  2.341447352  0.4883558953
## [354,]  -2.11663452  -0.296368297  0.866722769 -1.449012414  0.5390360723
## [355,]   3.00954689  -0.243545681  1.981989096  1.678249015 -1.7021761518
## [356,]   0.98178471  -0.796551513  2.367338148  0.156784682 -1.5450702314
## [357,]  -0.35757923  -2.125968004  0.707586438  0.184582384  0.1024797906
## [358,]   3.19111003   1.847526445  0.099310968 -0.022762481 -0.1788449118
## [359,]   2.99060189  -1.629958015  2.554470244  1.344703963 -0.0407045185
## [360,]   3.19110631  -0.578830133  0.489333658  0.044554975  0.7229711106
## [361,]   4.58792496   2.758699732  0.979680613  0.362519486 -0.2198878361
## [362,]   2.48373073   1.187894183  0.348470172 -1.255187427  0.1292803966
## [363,]   2.39655663   0.250524355 -0.326850211 -0.277129058  0.3545026443
## [364,]   0.77892982   2.122475872  0.320506876  0.079179253  0.0857346246
## [365,]   3.13722800   1.486714010 -1.197824530  0.453050754 -0.8401627046
## [366,]  -2.73260737   3.941699950 -0.017154393  0.299846924 -0.2830181364
## [367,]  -6.22155168   1.388887616  2.731833465 -1.092200460  0.5821459417
## [368,]   2.22182078   0.356846723 -1.100713817  0.186058986  0.2390645934
## [369,]  -5.30247440   6.717504288  1.484358772  1.774948969  1.0726100091
## [370,]  -7.24162919   3.652255530 -0.155565119  1.225750236 -0.2973284171
## [371,]  -4.20352196  -1.175208822 -1.588620367 -0.977982825  0.1174778025
## [372,]   2.49743889   2.016761090 -0.730631718  1.983278202 -1.1349569236
## [373,]  -3.63181933   1.954720962 -0.828046542  1.378539602 -0.9935467144
## [374,]  -3.51615443   3.855214937 -1.021630135  1.382926471 -0.3203822623
## [375,]   2.61264945   1.101505251 -1.239645246  0.908676936 -0.3781480185
## [376,]   0.09602363   0.129733431 -1.669994689  1.526133855 -0.4027131208
## [377,]  -2.04305926  -6.421169887  1.273001142 -0.109645013 -4.5986701548
## [378,]   3.06405348   2.180177374 -0.278817341 -2.935974046 -0.4728184934
## [379,]   1.60217670  -0.292338995 -1.584830948  0.908898609 -1.2347827015
## [380,]  -3.76262144  -5.980033549 -4.876070721 -1.119887331  0.5637410178
## [381,]   0.92475292  -2.300457270 -1.594708683  1.674764766  1.4257318574
## [382,]   3.28545874  -0.201134359 -0.627204410  0.612295926 -0.1706180435
## [383,]   1.55348525  -0.978996316  1.195507876 -1.773616381 -3.4960491469
## [384,]   0.39842934  -2.159312724 -0.944773717  0.372153562 -1.0117604959
## [385,]   2.29854534   0.931258175 -1.128959899  1.451099756 -1.5542727004
## [386,]   0.54242409   1.315910048  0.994879134 -1.483570015 -0.2027995563
## [387,]   2.05700950  -0.320153445 -0.122350756  1.019962435 -2.0773397982
## [388,]   3.42150749   2.443368505  0.045009146  0.785450794 -1.6017729103
## [389,]   0.47199125  -3.699574203  1.952067274  0.995440694 -3.8110426797
## [390,]  -4.69936579   0.195783486  3.753730061 -1.003344863 -0.3283619127
## [391,]   3.64017727  -0.786168171 -1.161124120  2.097029762  0.4236952100
## [392,]   3.59152918  -2.602797030  1.850401478  0.089806410  2.4403924824
## [393,]  -4.14544978  -0.766814129 -0.887194062 -0.008362190  0.6044479220
## [394,]  -7.66539681   0.859727681 -2.151756805  0.254499442  0.2362625219
## [395,]   2.00861205  -0.429311811 -0.103997306 -0.160151144  1.5081790902
## [396,]   2.91826573   1.698977554  0.295467269 -0.413812779 -0.3635999269
## [397,]   0.50029759  -0.106637635 -1.027843564 -0.304616687 -0.1389987468
## [398,]   1.90981814   0.650821226  1.449013512  0.400350786 -2.0611887662
## [399,]   3.78177167   0.325859645 -1.057150017  0.605475000 -1.5248138903
## [400,]   2.70601296   0.219472629 -0.314228262  0.055204339  0.0482116178
## [401,]  -6.28414409  -2.034757025 -3.179284831  0.155406788 -0.2023110488
## [402,]   3.42775463   0.991737410 -0.731051348  1.342541631 -0.2356318119
## [403,]   1.99962900   0.293068594  0.618659534 -0.352201845 -1.1637958353
## [404,]   2.47111877   0.334752480 -1.481058853  0.464828450 -0.0489496329
## [405,]   3.64405137   1.240273815  1.385405524  1.612540488  0.1728393129
## [406,]   2.34412427  -0.682141105  1.131738080 -0.302837266  0.5411994776
## [407,]   1.14199209   1.960446508 -1.239628958  1.477776286 -0.4837568556
## [408,]   1.34966974  -0.369249002  2.484489568 -1.139714833 -1.9041890533
## [409,]  -2.76094145   1.077685260 -1.178586912  0.413794976  0.1644668356
## [410,]   1.96759233   0.175693916  0.420361503 -0.785620740  0.8604953761
## [411,]   2.92861019   0.494421191 -1.016176763 -1.684940447  0.5652328718
## [412,]   2.92380175  -0.377000536 -0.886014238 -0.115243469  0.9848137147
## [413,]   3.99267514  -0.959012260  0.204224433 -1.508902626 -1.7077458028
## [414,]  -0.15500167   0.437623166 -0.461040030 -1.453254393 -0.8550878945
## [415,]   0.93326963   2.104094210  1.431657320 -2.891717258  1.2742945854
## [416,]   1.92792536  -0.891682104  0.042307522 -0.558392976  1.2792046734
## [417,]   2.62003325  -2.499901968  2.432858840 -1.876362157  3.1480466996
## [418,]  -5.99833869   0.090949196  1.709697317  0.946542059  1.1740030698
## [419,]   2.91930912   0.009204582 -0.900511128  1.789753754 -0.5764724361
## [420,]   3.33900683   0.022205192  0.502858739 -1.141258134  1.5633857813
## [421,]   2.01314368  -0.777767778  0.125468395 -0.659155792  0.0219104429
## [422,]  -1.98671401  -2.314011967  1.235217081  1.768220225 -0.1438692164
## [423,]   1.66813615  -0.861560770 -1.009417991  1.322731355  0.2813203167
## [424,]   0.37085180  -0.113512779 -0.997485893 -0.155233295 -1.4746581730
## [425,]   1.84733447  -2.538995601  2.003584668  0.483946194  3.5055609223
## [426,]   4.69890766   0.431922385  0.005300424 -1.369403704  0.0850247711
## [427,]   1.28205907  -2.548666752 -0.083786622  0.770833997 -0.5564209652
## [428,]   2.31221232  -0.401678043  0.274381769 -1.668994639  0.5362392557
## [429,]   4.65498928   0.781611021  0.191953023  0.493247906 -0.5356508029
## [430,]   3.94000659   2.028231657  0.691127602  0.512954900 -0.3398155529
## [431,]  -4.94550694  -3.003421435 -1.752529645 -0.671769430 -2.8622552978
## [432,]   0.91499842  -2.476833776  0.362287911  0.261736218 -0.1383500423
## [433,]  -4.54511193   0.815283142 -0.518299038  0.915534201  0.0714231738
## [434,]  -4.43843746   0.991566424  1.441051113 -0.574529073  0.3572756344
## [435,]   2.19305464   1.803766114 -0.434726892  0.953104432 -0.5533135626
## [436,]  -0.66385679  -0.436476802 -2.678425146 -0.728585540  0.0277629459
## [437,]   2.23890605   0.454189872 -0.465118333  0.188558748  0.8275650396
## [438,]   2.12331215   1.193746541  0.489940891  0.854644353  0.1058427332
## [439,]   2.61301823   1.830449830  0.763657618 -0.822442197  0.3005228170
## [440,]   3.20814515   2.233177743 -0.166078298  1.129064342 -1.2590809462
## [441,]   0.30648073  -2.183077955  0.039251705 -0.486027975 -2.0876130896
## [442,]  -2.47018342   1.498506224  0.590933256 -2.265358224 -1.4046042766
## [443,]   3.45168126   2.134583340  0.196989342  1.532828161 -0.9420463979
## [444,]   3.89709781  -0.730133530  2.134193239 -0.780486142  0.8318195830
## [445,]  -0.98086448   2.208486712 -1.698424795  0.970118413 -1.1822180725
## [446,]   1.25614629  -1.066752885  0.259247160 -1.240660490  0.3928701037
## [447,]  -3.24256054   1.776795240 -1.791577273 -2.482874793 -0.5498682865
## [448,]   1.55585043   1.037014643 -1.300101127  0.621126067  0.3790198963
## [449,]   1.24815985   1.587442008 -0.326126484 -0.924508658 -1.5340001134
## [450,]  -4.32784530   4.045772565 -0.192336290 -0.290357973 -0.6103038017
## [451,]   1.07650412  -1.802032564  1.779475879 -1.627520204 -3.7384644652
## [452,]  -2.50954497   2.526584455  0.797500590 -0.822950476  0.4288865709
## [453,]   2.21514321  -0.029865010  0.635900610 -3.373732618 -0.4795727546
## [454,]   1.17279871   0.474422064 -0.481147553  2.142074589  0.2430866392
## [455,]   2.83380799   1.017230750 -1.485323075  0.456004436 -0.1146041549
## [456,]   1.85545330   1.570011674  0.825756166 -3.926794310  0.2206325260
## [457,]   1.32744636  -0.776412499  1.255653387 -3.782215661  1.2439684480
## [458,]   2.80030738   1.664836753 -0.193847761 -2.231144249  0.2050662449
## [459,]   3.17177797   2.073908798  0.074834422 -1.868185223  0.2091427763
## [460,]   4.08348433   0.484283961  0.630808963 -3.399741429  0.0182086861
## [461,]  -3.47243837   1.671413723  0.856073545 -1.155750941  1.3813559853
## [462,] -16.30488665   7.769016888  6.229933870  2.326026514  1.7079531344
## [463,]   2.55786437   2.491852880  0.170162861 -2.107901855 -0.9783779753
## [464,]   2.96627878   0.068786611 -0.777727248 -0.046625788 -0.2280062503
## [465,]   2.75500634   1.792341696 -0.757147909  0.024097077 -1.2827836689
## [466,]  -1.36913518  -2.108156394 -0.852969723 -0.723132156 -3.8210171185
## [467,]   0.41729731  -0.116417262 -0.535671262 -0.363878888 -1.5121265752
## [468,]   3.83502421  -0.898388162  0.699948069 -0.219746414  1.3359873635
## [469,]  -5.92575082  -1.227216861  1.720074272 -0.473165926 -2.8810043579
## [470,]  -0.64491119  -3.422999542  0.607750202  0.234280083  1.2086350824
## [471,]   2.68148698  -1.442286469  0.339105123 -0.244601788  0.7919949893
## [472,]   2.03986918   0.902461858  2.840741857 -2.883294431  1.0158156443
## [473,]   1.39806620   1.770668244 -1.478260847  1.306959009 -1.8037276563
## [474,]   3.53330636   1.245758018  3.382434941 -4.661948944  1.8740788308
## [475,]   1.98877953  -1.897792693 -2.029212586  0.911103793 -1.2304717877
## [476,]   1.99642872   0.206189711 -1.639882150  1.038296903 -0.9034160493
## [477,]   0.52020039   0.972512103 -0.323850426 -0.543521127 -1.4281800593
## [478,]   3.16958159   2.087215768 -0.977945244  0.386756799 -1.4182276802
## [479,]   2.20077374  -1.284908734 -0.886619084  0.700486694 -0.1796630638
## [480,]  -3.82107090  -2.303209735  0.027521977  0.669669644 -1.2886313605
## [481,]   2.98286009   0.672747298 -0.589970772 -0.593827781 -0.4615631694
## [482,]   2.47887396   2.361880555 -0.432234246 -0.383132558 -1.0372087673
## [483,]   1.27099312  -0.509385643 -2.237023334  1.670906156  0.1175030515
## [484,]   2.23319191   1.297562775 -0.900644424  0.433712494 -0.1827652155
## [485,]   0.05613371   0.227183495 -2.253532782  2.708217480 -0.8010805172
## [486,]  -2.31535334  -4.385275755  1.776847691  0.968563355 -2.6430509823
## [487,]   2.28232306   2.464672105 -0.820466562 -0.040767325 -1.0918206156
## [488,]  -4.75043499   1.488114177 -1.252648906 -0.052540766  0.0965398306
## [489,]   1.72479328  -0.997300316 -0.080167877  1.063711106  1.4343549437
## [490,]   0.74112965   2.449879331 -1.995953713 -0.457537180 -0.2610613824
## [491,]   2.89176621   0.977084588 -0.804935982 -1.719266485  0.0289580691
## [492,]   1.65306732   4.551659142  0.751661685  1.646873743 -1.4018393993
## [493,]  -3.10079133   1.235066483  1.286223339  0.608113830  1.1212732858
## [494,]   4.06069761   0.560461075  2.174771231  1.374658804 -0.1992898120
## [495,]   2.79087498   1.076940539  0.843799658 -1.109231547 -0.0048653882
## [496,]   1.47362330   1.589695437  0.319710133 -0.798129881 -0.1579186103
## [497,]   0.22919297  -1.514570755 -2.214334625  0.555081328 -0.2509810467
## [498,]   2.55101378   0.763228924 -1.607988258  0.059875184 -0.5054003068
## [499,]  -3.71243855   1.057755506  0.521494703  1.395773631 -0.3682903454
## [500,]  -5.09036286   2.017432706 -0.708746074 -0.082722167 -0.3834794788
## [501,]   0.60008810   0.837717560 -0.686437977  1.154318132 -0.9815689274
## [502,]  -2.78794673  -3.382584454 -0.752414277 -1.332009710  1.5841377430
## [503,]   1.40753273  -1.504446838 -0.353584900  1.120754558  1.8100776146
## [504,]  -7.25279714   5.490904302  1.909245947  1.894050092 -0.3960294570
## [505,]  -1.29772469  -7.723057325 -0.688309017  2.890184346  2.0135831354
## [506,]  -1.07574673  -8.287483337  0.433810751  1.952471847  1.3946448821
## [507,]   1.24866183  -1.594281055 -1.355282076  0.126156474 -0.0233994859
## [508,]   1.25582341  -4.113567176 -0.412366931  1.053246923  1.1385251781
## [509,]   1.16550969   1.664229389 -0.737229323  1.760617958 -0.7377031703
## [510,]  -4.09054331  -2.800463137 -0.506987325 -1.975580106 -0.1327084112
## [511,]   1.88597978  -1.670721680  0.119692299  1.217144238 -2.5658122684
## [512,]   2.76500279   2.159148972 -0.021077623  1.608860107 -0.7157489170
## [513,]  -2.22503669  -1.939927827 -2.283594176 -0.339561903  0.5363853531
## [514,]   1.13058210   1.409761524 -0.564556376  1.993206904 -0.5280229629
## [515,]   0.73312738   1.941988438 -0.274994234 -0.337526159 -0.6604100570
## [516,]   2.33161916  -0.789451973 -0.349735677  0.440471990  1.4212995780
## [517,]  -2.69485257   1.942001189 -0.959719996  0.459104689  0.5839845732
## [518,]  -3.37604410   2.331377578 -1.200875536  0.553126259 -0.5274167311
## [519,]   0.19969487  -1.075413752 -0.672557052  0.627893020  0.8395117260
## [520,]   1.17499204  -1.010481061 -0.711142576  1.065131254  1.4206509043
## [521,]   1.29150016  -4.959860548  0.345622908  2.238565182  3.8371535988
## [522,]  -8.62316838   3.456410638 -0.178899380  1.176129200  0.0228851505
## [523,]   4.42556234   0.785345015 -0.473002900 -0.696004578 -0.1037131678
## [524,]   0.61929383  -0.635789842 -0.488421490 -0.015141135  0.1063131129
## [525,]   3.24945659  -1.284794677 -0.218284421  0.307537632  0.0993416275
## [526,]   3.34997942  -2.670950443 -1.777523046  1.388364375  0.3541295063
## [527,]   0.85904712  -0.096763381 -2.811570840  0.184161855  0.6295214724
## [528,]   3.15384692   0.870776432 -2.193784489  1.448593014 -0.4310565911
## [529,]  -0.34622347  -1.539870352  2.843951628  1.908132516  0.5713316529
## [530,]   2.45924278  -0.600319751 -1.170435277  2.209110148  0.6913036191
## [531,]   1.52875558  -0.404861554  0.603933344 -0.346866279  0.7853562456
## [532,]   1.77202587  -0.803503014 -2.026135257 -0.686728928  0.6155504122
## [533,]   2.67808519   1.483403662 -1.740162222  1.022590841 -0.2972072410
## [534,]  -4.02489378   2.938844225  1.658026507  0.224969353  0.5131432277
## [535,]   2.13447312  -1.517245623  0.178807901 -0.500336469 -0.6824469628
## [536,]  -5.16086993   2.380108987 -0.421906048  0.882650977  0.2092240560
## [537,]  -0.53546080  -0.380380451 -0.442745212 -1.877719723 -0.2266699710
## [538,]  -0.34282174  -3.531373815  0.069607554 -1.549307121  1.9552004887
## [539,]   4.19339024  -2.365311059  1.325978010 -2.037710987  1.7603677988
## [540,]   1.14182718  -5.594535868  1.299893249 -2.186325923 -0.7649016389
## [541,]   1.66401100  -2.387517361  1.500928782  0.875181074 -0.4841195986
## [542,]  -1.01082308  -1.091429307 -0.632142163 -1.756972472 -1.0459061568
## [543,]   1.29978604   1.819814057  0.372979316 -1.846544182 -0.1994515741
## [544,]   2.37134219   1.680097929  0.384190094 -3.014076570  0.0382130321
## [545,]   1.66440651   0.213774641 -0.147942249 -0.196878516 -0.5559910407
## [546,]   1.92598353   1.136739705  0.477781900 -1.156482818  0.2021640255
## [547,]   4.23349159  -0.184110499 -0.326131445  0.587786142  0.7040073381
## [548,]   2.67551655  -2.313756961 -0.053800867  0.340150357 -0.4502519824
## [549,]   3.83312511  -0.495813665  0.922428047 -0.551386509 -0.0799652223
## [550,]   2.54919727  -0.228129228  1.412934778 -1.969057256  1.4550448383
## [551,]   4.69079604   0.766803238  1.542607509 -0.778334167  0.7842069600
## [552,]   2.02325691  -1.260133116  0.504482203 -1.134529125  0.1141621816
## [553,]   2.89340232   1.450359601  0.779859803 -2.967836815  0.3568359788
## [554,]   3.49912218  -1.799249342  2.764024589 -0.865545694  0.6248149194
## [555,]   2.15201013   0.829339088  0.564300199 -3.009108230 -0.5653278607
## [556,]   2.05327740  -1.615038205  1.837342797 -3.110797801 -0.2108571316
## [557,]   3.87388097  -1.083301553  1.858308794 -0.433358360  1.6859553304
## [558,]   4.06028949  -0.122061034  3.235925374 -3.466133119  2.2399371646
## [559,]   0.09858059   0.213372093  0.388587548 -1.011820230 -2.9864399976
## [560,]   1.08841850  -1.291711328  1.428122289 -3.369171941 -0.9465087393
## [561,]   0.48134743   0.177863190  1.031200235 -2.008512908 -0.3268156112
## [562,]   4.86602793   2.129232607  3.411187296 -5.129474909  0.4884909563
## [563,]  -5.91241029  -3.479575000 -3.259923297 -3.914141413 -1.7148732547
## [564,]  -8.73365338   0.573350185  0.896301447  0.384811315 -0.6784463175
## [565,]  -6.43365455   3.573672989  2.457324373  1.176279049  0.0747585153
## [566,]  -3.79004753   3.580897052  2.086640366 -2.503824654  0.5102735378
## [567,]  -1.25507494   1.900624364  0.562235817 -2.087390339 -1.8084001296
## [568,] -10.36567336  -1.670540206 -1.875379194 -2.353959892  0.0337122683
## [569,]   5.47042990   0.670047220  1.489132801 -2.297135901  0.1845409324
##                 PC6           PC7          PC8          PC9          PC10
##   [1,]  1.410183639  2.1574715203  0.398056982 -0.156980233 -0.8766305374
##   [2,]  0.028631162  0.0133463502 -0.240776600 -0.711278966  1.1060217613
##   [3,]  0.540976145 -0.6675790845 -0.097288135  0.024044486  0.4538760367
##   [4,]  3.050737497  1.4286536346 -1.058633755 -1.404204115 -1.1159933184
##   [5,] -1.225416405 -0.9353895017 -0.635816609 -0.263573547  0.3773724202
##   [6,] -0.450642134  0.4900139551  0.165298432 -0.133355760 -0.5299649041
##   [7,] -0.128835073 -0.3013023315 -0.083624609 -0.079954220  0.2189506984
##   [8,] -1.255934103  0.9732434974  0.652763899  0.247965464  0.9997064885
##   [9,]  0.559052820 -0.2149145974  0.686736938  0.511473855  0.0291618051
##  [10,] -0.723272337  2.5176245802 -0.364827879 -0.716766009 -1.1646060593
##  [11,]  0.127219899  0.6244628561 -0.165603833 -0.301115608  0.3759046163
##  [12,]  0.764194227  0.6655068738 -0.619000411 -0.400588340 -0.3307781202
##  [13,]  2.592290301  0.9406696600  3.318863750 -0.747130974  0.3955980681
##  [14,]  1.006774257 -1.7974995418 -1.105684467  0.267389882  0.4391951701
##  [15,] -0.349408795  0.7422274132  0.280679206 -0.674510305 -0.1155553104
##  [16,]  0.495342130  0.9142524133 -0.302257713  0.456538430  0.4467643551
##  [17,] -0.761520960 -0.0867706702 -0.029483040  0.502783775 -0.4992331367
##  [18,] -0.751827782  0.4415962916  0.413405991  0.018656683  0.3563165037
##  [19,] -1.136688687 -0.2510619539 -0.741499503  0.410086322 -0.5708248435
##  [20,] -0.048594023 -1.2006310194 -0.403270875  0.404944121  0.0059203674
##  [21,]  0.430462491  0.3381860916  0.861201670 -0.187036602  0.3606065559
##  [22,] -0.769391365 -0.1908707908  0.244247147  0.546415425  0.0076299444
##  [23,]  3.020386239 -1.0062943167 -0.104544724  0.168363304 -0.2454047607
##  [24,] -0.595316618 -0.0747626295 -0.180094245 -0.363806008  0.6909368005
##  [25,] -0.812165001  0.7996017629 -0.419539913  0.810965561  0.0214595144
##  [26,]  1.183160422  0.6013244034  1.306262282  1.100042783  2.2842657360
##  [27,]  0.786665153  0.2896641020  0.495541562  0.113090873  0.2951812417
##  [28,] -0.906797174 -0.6452669891 -0.340174492 -0.043873679 -0.3961957456
##  [29,]  0.192679233  0.1609885641 -0.378501497  0.356974453 -0.5691360315
##  [30,]  0.036227947  0.1838685926  0.218709799 -0.381333094 -0.0364970759
##  [31,]  0.241867529  0.4615706215  0.291813749  0.284492214  0.1182178679
##  [32,]  1.233593969  1.9763494638 -0.202453666  0.564148659 -0.2297663753
##  [33,] -0.190839648 -0.8888020606  0.243842164  0.442519010  0.1433737325
##  [34,]  0.267243832  1.0317090641 -1.141727259 -0.566293378  0.2446991603
##  [35,]  1.000905829  0.7700944229 -0.210139235 -0.585132155 -0.0747302216
##  [36,]  2.009267717 -0.7199616429 -1.411392236  0.196789071 -0.7431027433
##  [37,]  0.568095150 -0.1425954318 -0.488198042  0.390894097 -0.3824484486
##  [38,]  0.290013739 -0.8043318792  1.707341340 -0.891664549 -1.0876247249
##  [39,] -1.493142577  1.2791292757  1.498249655  2.100532774  0.0114924931
##  [40,] -1.036438899 -0.1775681622 -0.198083551  0.431153558 -0.4385877226
##  [41,]  0.928295680  0.0418357439  0.048599880  0.666574547  0.3902914311
##  [42,] -2.120772389 -0.4965417472  0.484027443  0.912512891 -0.4303234931
##  [43,]  4.307303747  0.4337837927 -1.387017258 -0.352517752 -0.9339783433
##  [44,]  0.242568260  0.6132339088  0.067809257  0.282512565  0.1518262957
##  [45,]  0.110049368  0.2333988676 -0.174872997  0.544441256 -0.2067359385
##  [46,]  0.423532149 -0.7874816331 -0.790091300  0.111457042 -1.0551322678
##  [47,]  0.575420451  0.2230057137 -0.867569780  0.328258562 -0.1456716219
##  [48,] -0.281861620 -0.1604792421 -0.018943396  0.591809797 -0.1053337966
##  [49,] -0.692882067  0.1971605392  0.040044188  0.419441177 -0.6168907916
##  [50,]  0.544804546 -0.6838772921  0.555862941  0.605703404  0.1987895162
##  [51,]  0.266013819  0.4536379429 -0.123851495  0.259381187 -0.4343429520
##  [52,] -0.256313209  0.4449438979  0.057879905 -0.492076521 -0.2410267010
##  [53,]  0.629337135  0.0607736151 -0.510873270  0.413623505  0.8230489282
##  [54,]  0.707227400  0.6479398411  1.537761700 -0.614290601  0.0886086788
##  [55,] -0.656077776 -0.2152637743 -0.207515896  0.505338373  0.1085018162
##  [56,]  1.277739611 -0.3925629141 -0.745416793  0.301153902  0.0751610030
##  [57,] -0.178434830 -0.1853434904 -0.309233059  0.012534355 -0.1128753503
##  [58,]  0.461927636  0.5362098378  0.951178388  0.073379908  0.1941817154
##  [59,]  0.705119501  0.4873781448 -0.297723909 -0.127261763  0.7362638224
##  [60,] -0.900267281  0.4064726785 -1.225062124  0.345609537 -0.4642608787
##  [61,]  2.538550035  0.7457813449  0.909941133  0.262199059  1.3178790775
##  [62,] -0.815018482 -0.3959097935 -0.230734976  0.102956869 -0.9272860914
##  [63,] -1.218994501  0.8193030850 -0.330742314  0.528189577 -0.4855301241
##  [64,]  2.955682829  0.2103798445  0.627427082 -0.232120660  0.0413657355
##  [65,] -1.242117920 -0.0057834579 -0.385706296  0.801372546 -0.1817471124
##  [66,] -0.727422417 -0.5309593004  0.474393258  0.003939003  0.1728882560
##  [67,] -1.188527693  0.1693780934 -0.029824460 -0.111145907 -0.2713131090
##  [68,] -0.405353080 -0.5265287503 -1.082071976  0.427426065 -0.3912329742
##  [69,]  2.213816387 -2.5787909992 -1.298010892  3.780791875 -2.7357511959
##  [70,] -0.433947228 -0.8493285940 -0.334869937 -0.004978691 -0.3104418547
##  [71,] -0.291543973  0.2832433298 -0.086188560  0.326867199  0.0333168740
##  [72,] -1.638316786  2.4262266414 -1.317108728 -1.883468421  3.1898325590
##  [73,] -0.539586813  1.5624901202 -0.593662500 -0.672507942  0.0611282077
##  [74,] -0.919638446  0.6971724884  0.393036492 -0.357905538 -0.1474184494
##  [75,]  0.034838302  0.1200189004  0.459971988  0.314694924 -0.0155400843
##  [76,] -0.994688029 -0.9081210535 -1.100360740  1.244777578  0.0926553152
##  [77,] -0.612562561 -0.7756714142  0.246838044 -0.772831741  1.5166900630
##  [78,]  0.682870529  1.3985754634 -0.719241167 -0.096664805  0.5085691762
##  [79,]  4.876508199 -1.1544779461 -0.483077495 -1.170391748 -1.3237161139
##  [80,] -0.072350138  0.0536554932  0.355866547  0.048832592 -0.1077491295
##  [81,] -1.501869476  0.1435614258  0.486258862 -0.122378079 -0.0390292436
##  [82,]  0.138012244 -0.3263920580  0.151919734 -0.226864771 -0.5036154424
##  [83,] -2.186236690  0.0355707110  0.547079286 -1.647859246  0.3961746350
##  [84,] -1.421297891 -0.0432176692  2.012767522 -2.966728252  0.0222412116
##  [85,]  0.882263930 -0.2550878307  0.229994161  0.423649141  0.1477716874
##  [86,]  0.967176566 -0.1536701262  0.192125163 -0.083450911  0.4426520533
##  [87,]  0.567360307 -1.6613223577  0.349250281  0.571523884 -0.1210561314
##  [88,]  1.560091353 -0.1983680707 -0.643025712  0.183841722  0.4623711739
##  [89,]  0.223702425  0.0769126070  0.148776905  0.262252261  0.4555666494
##  [90,]  0.842299884 -0.1736551116  0.614011283  0.283254129  0.3987023515
##  [91,]  0.325518164  0.2995505173  0.128752056 -0.246304891  0.5210683990
##  [92,] -0.199459121 -1.7255946363 -0.786058401  0.116745956  0.1441268207
##  [93,] -0.292110132  0.0957807360  0.413725996  0.390523505 -0.5899606072
##  [94,] -0.321113861 -0.5677543179  0.395718555  0.058107568 -0.4912485698
##  [95,] -1.066707998 -1.0421552988 -0.283564277  0.637899776 -0.2969722678
##  [96,]  1.783555798  0.0004244298 -0.292506839 -0.580370555  0.4991648297
##  [97,] -0.096852967 -0.0225249946  1.596299697  0.179428829  0.4099629648
##  [98,] -2.351934315  1.1157841763  0.148452301 -0.906614963 -0.3165086702
##  [99,] -0.430903499  0.4844971328 -0.290694588  0.057293175 -0.3825068496
## [100,] -0.853188272 -0.5060704070  0.634423963 -0.237141676  0.1392901935
## [101,] -0.595802895  0.0029648840  0.062601958  0.797723981 -0.2095356865
## [102,] -0.899700995  1.4116521142  0.324334412 -0.505544952 -0.1898542596
## [103,]  0.342937555 -0.2377974400  0.513345470  0.454774516  0.1528759939
## [104,] -0.991047162 -0.5084776263 -0.051816347  0.885904532  0.1673165990
## [105,]  0.940750946  0.1577998775  0.592437419  0.477922672  0.6483605373
## [106,] -2.202856495  0.5190182681  0.919491499  0.024774004 -0.5966611023
## [107,] -1.608771501 -0.4979118440  0.452844869  0.527102050 -0.4592233167
## [108,]  0.359599477  0.1231328050  0.263560697  0.289616641 -0.1759008102
## [109,]  1.020860934 -0.0954075198  0.767942841  0.627017416 -1.0979068211
## [110,] -1.439608866  0.2115695617 -1.388075349  0.448512027 -0.6290141193
## [111,] -1.095444306  0.2037178296 -1.218964989 -0.570481422 -0.7426654271
## [112,] -1.458702835 -1.0401187280  0.120431563 -0.227163027  0.3361622567
## [113,]  0.833123888  0.4111745398  0.970303417 -0.535303964 -0.2484248020
## [114,] -1.261777184  0.1057625720  0.713697894 -0.410313572  0.6957360576
## [115,] -1.706440486  0.5119879213 -0.337466388  0.678858808 -0.4910440978
## [116,] -1.337752701  0.4595072608 -0.488509104  0.354100824  0.4414446401
## [117,] -2.293687595 -0.9185965070 -1.898086528  0.154241095 -0.4446864733
## [118,] -0.767555623 -0.2067958374  0.209629326  0.284564474 -0.0334444954
## [119,] -1.492492721  0.4264319465 -0.275527717  0.357573419  0.0964420085
## [120,]  4.975158195 -0.9917687699 -1.044205851 -0.483438131 -0.3707162449
## [121,] -0.438000429  0.0569341545 -0.463647307  0.245730642 -0.4929124233
## [122,] -0.579613971 -0.2505498519  0.361729650 -0.241886354  0.1402872611
## [123,] -0.946220851 -1.2957391097 -0.792061520 -1.694971898 -0.0776531867
## [124,]  0.180693692 -0.5030415897  1.294717404 -0.091526472 -0.3633815227
## [125,] -0.247250211 -0.1912870373 -0.070698364 -0.197988493 -0.4727441430
## [126,] -0.226920405  0.3213445519  0.269963020 -0.171115561  0.2946382608
## [127,]  0.148751350 -0.0415938395 -0.272031126  0.771906177 -0.0588503290
## [128,]  1.467236870 -0.1445960967  0.172105084  0.253497334  0.2448693537
## [129,] -0.533827466 -1.2652594966  0.721508750 -0.385475878  0.5934329421
## [130,]  0.678064911 -0.7403080258  0.634019823 -0.195963883  0.7616033847
## [131,]  0.654051923  0.3144589921 -0.222639255 -0.683091883 -0.0068671508
## [132,] -0.785225256 -0.6210090246  0.214754724  0.669006569  0.1309451308
## [133,]  0.686370956 -0.3132321125  0.524909363  0.333859949  0.7119644915
## [134,]  0.246141926 -0.8388130034  0.525219945 -0.232429603  0.2414018451
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## [517,] -0.491293222 -0.5167539200  0.050028508 -0.131357405  0.2258787420
## [518,] -1.017677377 -0.0261084918  0.443355468 -0.658166813  0.5299438963
## [519,] -1.286369931  0.7480548590  1.375305788 -0.257540461 -0.2080778673
## [520,] -0.265206232  0.1942744924  0.462310866  0.357702019  0.7940768989
## [521,] -0.548135411 -0.8140726857 -0.987108671 -0.070507407 -0.0537361968
## [522,] -0.006685146  0.9611743974  0.397621795 -1.256638663  0.8486917334
## [523,]  0.097095633  0.7218828231  0.508127340  0.060557805  0.3878654534
## [524,] -0.600188263  0.1391868086  0.295156517 -0.243768633  0.0023377369
## [525,] -1.401965911  0.9527774834 -0.299971512 -0.503892654 -0.7846233548
## [526,] -1.210209018  0.8160391133 -0.373064638  0.292981675 -0.3609872357
## [527,] -0.364718273 -0.0462160782 -0.125638066  0.312293703 -0.2469249564
## [528,]  0.325770470 -0.0944504391  0.149150397  0.318904984 -0.2288534014
## [529,] -1.686010994 -1.7109061685  2.408540813  0.332918111 -0.1176166151
## [530,] -0.851940525 -0.0288485824 -0.205098471  0.032406632 -0.3895059803
## [531,] -1.101161685  0.0869517853  1.295452125  0.161515938 -0.9103205148
## [532,] -0.289073515  0.4730366470 -0.069618747  0.543463275  0.0572082633
## [533,] -0.197903630  0.4337496082  0.168973422  0.024829540  0.3191275798
## [534,]  1.934520374 -0.7275859760  0.757319150 -0.175980334  0.2702433954
## [535,] -1.550311718 -0.7176961616  0.139629661  0.188290346 -0.3701820155
## [536,]  0.578720770 -0.5430102167  0.951930849 -0.247809950  0.5286878926
## [537,] -0.523378449 -1.1495594767  1.091132033  0.323915796 -0.1038818740
## [538,] -2.337461193 -0.4830815304  0.501982823 -0.069804388  1.2788258192
## [539,]  0.042391707  2.1668488112 -1.479915189 -0.322804378  1.1801175946
## [540,] -1.158207647  0.1913668076 -1.796559226  0.876067543  0.9484780485
## [541,] -1.188472456 -0.6771595730  0.146514414 -0.291391323  0.1026424111
## [542,]  0.425520296  0.3979358310 -0.835301076 -0.383809102  0.6190792834
## [543,]  0.765081147 -0.4663049042  0.398228821  0.364670551  0.7941292239
## [544,]  0.068753051 -0.4148574879  0.507946096  0.278027691  0.2875814970
## [545,] -0.930763180  0.5238585798  0.300437607 -0.356308724  0.4182343622
## [546,]  0.114797260 -0.1161527345 -0.013618636  0.058006015  0.1323174915
## [547,] -0.145962831  0.2596286888  0.149437375  0.564356936  0.5746698535
## [548,] -0.677751360  0.0640445882 -0.970113001 -0.454875027  0.0952997770
## [549,] -0.112569772  0.4740694793 -0.169694808  0.410188208 -0.2194120652
## [550,]  0.854769667  1.0210226174 -0.160349809  0.446749349  0.3987268089
## [551,]  0.850625097  0.7520064103 -1.069484886 -0.588800008  0.0688498920
## [552,]  1.783207929  0.3901520318  0.873654798  0.310967487  0.3653727356
## [553,] -0.582689902 -0.6178681677 -0.938396865  0.362221796  0.4485215927
## [554,]  0.411907169 -0.3073955477 -0.357594218 -0.143055766 -0.4514830478
## [555,] -0.549918834 -0.4839795902 -0.892397382  0.435103530  0.2439245685
## [556,] -1.640362885 -1.0878956916 -0.349885533  0.514611257 -0.0049422107
## [557,] -0.814176294 -0.4706597676 -0.071321985 -0.701263764 -0.0705817127
## [558,]  0.174755382  1.0763071056 -0.129380621 -0.426655069 -0.2770426795
## [559,]  0.012441261 -0.2900018002  0.312069081 -0.067804247 -0.3254840515
## [560,] -1.724352624 -0.3536636324  1.163315907 -0.207312716 -1.3904847631
## [561,] -0.991190143 -0.0485030055  0.195049336 -0.325578857  0.4286949972
## [562,] -1.109815814  0.4879418774  1.288150901 -1.389256180 -1.7451271378
## [563,]  1.012707855  0.2712037562 -0.091882489  0.372148526 -0.6298691742
## [564,] -0.300488375  0.0947410215  0.733436507  0.830362739  0.4502424273
## [565,] -2.373104852 -0.5956056075  0.035439747  0.987060511  0.2567626672
## [566,] -0.246493221 -0.7156966020  1.112380784 -0.105114917 -0.1085369986
## [567,] -0.533977345 -0.1925887705 -0.341586475  0.393570521  0.5204194692
## [568,]  0.567437190  0.2228855560  0.279992246 -0.541558028 -0.0892176149
## [569,]  1.616415088  1.6974579729 -1.045433644  0.373772231 -0.0476836145
##                PC11          PC12         PC13          PC14         PC15
##   [1,] -0.262724285 -0.8582592992  0.103296775 -0.6901967966  0.601264078
##   [2,] -0.812404827  0.1577837523 -0.942699807 -0.6529008436 -0.008966977
##   [3,]  0.605071514  0.1242777100 -0.410265611  0.0166650952 -0.482994760
##   [4,]  1.150501182  1.0104267377 -0.932450704 -0.4869883986  0.168699395
##   [5,] -0.650787016 -0.1104182769  0.387606915 -0.5387065429 -0.310046684
##   [6,] -0.109669824  0.0813699015 -0.026251351  0.0031339435 -0.178447576
##   [7,] -0.393343607  0.2419761651 -0.351941936 -0.2216015267  0.060855369
##   [8,]  0.196313828 -0.2777917914 -0.460630835 -0.0961356710  0.187478261
##   [9,]  0.560021577  0.0788169039  0.493001875  0.1120530076 -0.034237132
##  [10,] -0.548555069 -1.0841629631 -0.375475245 -0.0006033716 -1.206141020
##  [11,] -0.294276512  0.6099198621 -0.692298563 -0.1301140961  0.091099184
##  [12,]  0.150099383 -0.8725334105 -0.978852628  0.4132851288 -0.076575493
##  [13,]  1.119190867  0.0520074379 -1.983208918 -0.2667913889  0.492408131
##  [14,]  0.853628961  0.0628135272  0.194455743 -0.1212264306 -0.151174299
##  [15,]  0.637371253 -0.5439530565  0.152152510  0.0208341513 -0.504094726
##  [16,] -0.089892055 -0.0929155801  0.272937688  0.4193736451 -0.531937246
##  [17,] -0.283115330  0.3228336349 -0.873313571 -0.2068809463  0.026977460
##  [18,] -0.077022788  0.1450773283 -0.056826726 -0.5557727446  0.357788221
##  [19,] -0.382631859  0.0680073259 -0.762829689 -0.1781151366  0.186075363
##  [20,] -0.087947737 -0.3232036086 -0.240304220 -0.1497219434 -0.277740235
##  [21,]  0.252743308  0.1820993618  0.534747411  0.5364927035  0.630306593
##  [22,]  0.295829357 -0.1193713638 -0.105109885 -0.5505241800  0.208888166
##  [23,]  0.747761739 -0.7897394650  0.018967583 -0.3939657391  0.178368816
##  [24,] -0.845138812  0.1995874763 -0.760017755  0.1495561475  0.585041105
##  [25,] -0.600095326  0.2321645154 -0.719018102  0.0560160318  0.622570169
##  [26,]  0.196585356 -0.8095860291 -0.394727262 -0.9305675819 -0.282237083
##  [27,]  0.441362589 -0.9739851395 -0.516422067 -0.7074323955 -0.383724915
##  [28,] -0.412668030 -0.3158058348 -0.298472337 -0.2950812415 -0.235804579
##  [29,]  0.370382886 -0.1246372082  0.129900549  0.1958202715  0.175956263
##  [30,]  0.246904961 -0.0031839923 -0.222279620  0.1283529520  0.091747519
##  [31,] -0.496378073 -0.1044630774  0.885636344  0.0692396351 -0.376293016
##  [32,] -0.756864461 -0.2657615457 -0.522186276 -0.3000453967  0.072356014
##  [33,] -0.585836567  0.2547032178  1.119529771  0.2184706425 -0.403789163
##  [34,]  0.077919478 -0.1992975316  0.307173136  0.2036374012  0.068495324
##  [35,] -0.326307877 -0.4066154950 -0.351748055 -0.0564880712 -0.224784255
##  [36,] -0.328257659  0.2292843967 -0.619894462  0.2143138994 -0.067766013
##  [37,] -0.217741168 -0.0195015091  0.032551005  0.1704452228 -0.479641248
##  [38,] -0.032328754  0.4115801153 -0.245663247 -0.3627028769 -0.150524126
##  [39,]  1.047288688 -0.6130946673 -0.290379074  0.1249868104 -0.401912364
##  [40,]  0.591014507 -0.0004681369 -0.235544182 -0.4578511130 -0.668135575
##  [41,]  0.145009410 -0.0423201249  0.029903294  0.0054147710  0.005022251
##  [42,] -0.115306889  0.3312318699  0.019742154  0.2321540822 -0.128765770
##  [43,]  1.277954488 -0.8309410010 -0.922742372  0.9892697016  0.220725927
##  [44,]  0.160272727  0.1311301054 -0.144226466 -0.1816995714  0.160135565
##  [45,]  0.240085901  0.1091591008 -0.164573360 -0.0950096841 -0.193897144
##  [46,]  0.003089503 -0.1206287088 -0.149769253  0.3143049855 -0.268535008
##  [47,]  0.090090936 -0.0249037139  0.378695789 -0.2394451655  0.277696370
##  [48,] -0.289430944 -0.0732252281 -0.561084977 -0.2625113637 -0.646184357
##  [49,] -0.324354020  0.0931121402  0.393569102  0.5995102295 -0.169047859
##  [50,]  0.237322628 -0.0116411885 -0.208908133 -0.1508619753 -0.058578846
##  [51,]  0.639460669  0.6058597387  0.224644982 -0.0446479438 -0.040260858
##  [52,]  0.079686662  0.0240053741 -0.377273811 -0.4453178247  0.108861412
##  [53,]  0.025165467  0.1593213356  0.246020193 -0.5093448931 -0.077987883
##  [54,] -0.274018692  0.6533266173  0.601165133  0.6072878098 -0.501815152
##  [55,]  0.058487255  0.2677384961 -0.399395210 -0.0450747265 -0.036176457
##  [56,]  0.197754405  0.5401834853  0.058602197 -0.1399689340 -0.349863814
##  [57,] -0.605550553 -0.1156566994 -1.096994917  0.1275301954  0.597982425
##  [58,]  0.381160012  0.2814152874 -0.376294366 -0.0229779469 -0.331463457
##  [59,] -0.228334046 -0.1991733623  0.421272292  0.2167665417 -0.342304785
##  [60,] -0.621205924  0.3367435600 -0.148838932 -0.4425445128  0.511520357
##  [61,] -0.369405174  0.4379929489  0.090549052  0.3353742675 -0.536697760
##  [62,]  0.341145747  0.3759209730  0.161076437  1.1878815701  0.321697375
##  [63,]  0.717323304 -1.1859167706  0.589385595  0.3030289831  0.129915286
##  [64,] -0.511053316 -1.0091261525 -0.229682636 -0.7934928857  0.139211976
##  [65,]  0.223067407  0.0582255955 -0.512702935  0.1419434406 -0.178536288
##  [66,]  0.510796559  0.5421158683  0.129143047  0.1548683357 -0.008334256
##  [67,] -0.231340120  0.1520401549 -0.494456567 -0.0986237426  0.137340458
##  [68,]  0.171674515  0.0917544994  0.214040320 -0.4676657086 -0.320276347
##  [69,] -2.301916714  1.9478812125  1.103679434  0.2450717685  1.060326663
##  [70,]  0.131584973  0.5400548609  0.277961017  0.1141297357 -0.357009919
##  [71,]  0.428848750  0.2049555851 -0.371823339 -0.1793614799  0.291771882
##  [72,] -0.057789430  0.5105820620 -0.335217803  0.4799300038 -0.246973803
##  [73,]  0.018812465 -0.7441487192 -0.132429495  0.9380256690 -0.369608299
##  [74,]  0.379838236 -0.1163449791 -0.053581681 -0.1557475752 -0.059940319
##  [75,] -0.007559389 -0.2732435321  0.012174976  0.2578796832 -0.032393640
##  [76,]  0.140571180 -0.7691753712 -0.428252247 -0.1639715182 -0.078397551
##  [77,] -0.408291577 -0.3217815151  0.814890878  0.8570418853 -0.590679517
##  [78,]  0.845106205 -0.7038553721 -0.692840046  0.3237751499 -0.106235419
##  [79,]  1.209082105  1.2860572446  1.339239602 -0.5384927467  0.904755029
##  [80,]  0.127065020  0.1355485485  0.028337746  0.5169396446 -0.020759654
##  [81,] -0.786967580  0.0345574874  0.033439840  0.1843125970  0.447952176
##  [82,]  0.195944932 -0.3957884419 -0.141772499 -0.0148270384 -0.153420304
##  [83,]  0.253381955 -0.5690714729  0.753989687 -0.5460281371  0.432021867
##  [84,]  0.711729247  1.0499747090 -0.491325487  0.2623538872 -0.562578819
##  [85,] -0.745878240 -0.4598049292 -0.091626105  0.5523153709 -0.050962065
##  [86,] -1.004759517  0.0873877036 -0.757338038 -0.4174802891 -0.021205962
##  [87,] -0.552045457 -0.8029870413 -0.067392082  0.1127709163 -0.092173983
##  [88,] -0.433326769  0.5703689588 -0.119188327 -0.4170696748 -0.396379852
##  [89,]  0.016642280 -0.3158031850 -0.382598138 -0.4374455309 -0.208840242
##  [90,]  0.741940542  0.0200969537 -0.065901136  0.8226864857 -0.236364320
##  [91,]  0.724144967  0.5554322605  0.214432986  0.3277344219 -0.037958812
##  [92,]  0.937374393  0.4067146390  0.563287417 -0.7725393225  0.029255733
##  [93,]  0.049407605 -0.6890916537 -0.464225889 -0.4063362427  0.014895270
##  [94,]  0.148850187  0.1462808064 -0.128365565  0.7090543979  0.102181427
##  [95,]  0.609344020 -0.7423625667  0.222233620 -0.2428698410 -0.129345613
##  [96,] -0.644167720 -0.1613821271 -0.079839276  0.2971928632 -0.073910222
##  [97,]  0.585191831  0.4438091073 -0.230398088 -0.1827187582 -0.061170624
##  [98,] -0.329894644  0.3323522602 -0.138254531 -0.1072538655 -0.178613587
##  [99,] -0.146550183  0.0692879791 -0.002258044 -0.4559046799  0.100650887
## [100,] -0.407700886 -0.7112958461 -0.473288604 -0.2122558723 -0.075410969
## [101,]  0.237747713  0.4271403452  0.204387799 -0.0197655248 -0.095573905
## [102,] -0.610239332  0.4132517311  0.433086920  0.1177467385  0.467007135
## [103,] -0.443071154 -0.2120443990 -0.079804331 -0.2584303490 -0.021044615
## [104,]  0.020059110 -0.4442424967  0.246073297  0.1099355080 -0.277245907
## [105,] -0.021288531 -0.1327134811  0.583529561  0.4492001813  0.109180374
## [106,] -0.564911664  0.9193590685  0.012370125 -0.2168197204 -0.865838150
## [107,] -0.154806897 -0.1866572122 -0.633643189  0.4039318163 -0.108589053
## [108,]  0.066405975  0.0760311613  0.128667473 -0.0370781851  0.297765381
## [109,]  0.090596486 -0.7421530470  1.075751502  0.9368104783  0.533299888
## [110,] -0.320799033  0.1800812978  0.032265835 -0.3023335385  0.215077193
## [111,]  0.327746967  0.2046597881  0.120237817 -0.1783615485  0.194251397
## [112,]  0.650777643 -0.2933259538 -0.112544389 -0.7586715299  0.283199791
## [113,] -0.284942699  0.7269431412  1.212935475 -0.7159944693  0.251522069
## [114,]  0.313444155  0.1805138306  0.390237981 -0.1019964618  0.592050290
## [115,]  0.287039611  0.8103129309 -0.230171199 -0.1255945235  0.341881787
## [116,]  0.262233097 -0.0114082847  0.074866229  0.6410038747 -0.136567267
## [117,]  1.325817930 -0.5164890912  0.796713304 -0.1042779720  1.230334163
## [118,] -0.350864753 -0.3624834189 -0.267331949 -0.0465436932 -0.121090198
## [119,] -0.621096064  0.0271540484  0.412231332 -0.2522319704 -0.251715646
## [120,] -0.461739260  1.1619715314 -0.678297726 -0.0717007331 -0.361842486
## [121,] -0.400226119 -0.3973995978 -0.287870867  0.1832657469 -0.054754724
## [122,] -0.884232338 -0.0265148144 -0.611872230 -0.2217926975 -0.115027379
## [123,] -1.605406626 -1.1915246645  2.585042825  1.4099705217 -0.170480479
## [124,] -0.169709366  0.4297105020 -0.047285037  0.0122072432 -0.036636413
## [125,] -0.362363688 -0.6734598556  0.401537066 -0.1036802249 -0.014825254
## [126,] -0.110403142  0.1048734656  0.245746438  0.2803976055  0.304557047
## [127,] -0.072071812  0.3284031569 -0.153101749  0.1037941218  0.303579465
## [128,] -0.527253976 -0.5854540578 -0.196247938  0.4671088272 -0.058378954
## [129,]  1.402586521 -0.2463677463 -0.066270509  0.2971831513 -0.052689797
## [130,] -0.572576039  0.0549812995  1.581189240 -0.0155871349 -0.138038169
## [131,]  0.126816678  0.1476258572 -0.512886476  0.5304867215 -0.094368210
## [132,] -0.107029230  0.2008584867  0.446006724  0.1601414909 -0.417882075
## [133,] -0.317576548 -0.3185102735  0.169930917  0.5385371207  0.257834920
## [134,]  0.108520078 -0.2176028380 -0.246663060 -0.1122800805 -0.130306412
## [135,] -0.789606706  0.3201095342 -0.079950656  0.0860593677  0.240075552
## [136,] -0.329505157  0.3784692157 -0.267213663 -0.1702569329  0.026414747
## [137,] -0.353033591 -0.1571192120 -0.825311501  0.3718701966 -0.226420414
## [138,]  0.236340337 -0.2435946108  0.154797172  0.2682689068 -0.072006787
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## [522,] -0.051582825  0.4547128004  0.153356168 -0.7153258534  0.580934936
## [523,] -0.033046285  0.5166550389  0.271235410 -0.1720627144  0.217063747
## [524,]  0.355608475  0.1695525595 -0.605430233 -0.2977521130  0.326759656
## [525,]  0.277677070 -0.0613360894 -0.228041607 -0.3038124014  0.274499918
## [526,] -0.198384362  0.1371981708 -0.402980729 -0.2082814229  0.020684502
## [527,]  0.309372372  0.3712575625 -0.371678106  0.5098053277  0.253277883
## [528,] -0.231142007 -0.3013142461 -0.210626459  0.0825059098 -0.067296687
## [529,] -0.219224214 -0.7394725201 -1.201093310  0.3455021564 -0.152491963
## [530,]  0.216413846  0.6185806863  0.152807569  0.2086865471  0.229300628
## [531,]  0.451754145 -0.0200918317 -0.473948090 -0.1120267764  0.338057888
## [532,] -0.086230934  0.1354021183  0.176578027  0.5661383428  0.117613574
## [533,] -0.001336357  0.3487433903 -0.007837856  0.0831809793  0.343581930
## [534,] -0.166751294 -0.3515839280  0.035170250  0.1198560686 -0.056538788
## [535,]  0.025043256 -0.7064204808 -0.089502692  0.2487319465  0.329438223
## [536,]  0.119327440  0.2425811937  0.866156292 -0.4366418554  0.123746381
## [537,] -0.464140951 -0.1730744501  0.443281415  0.2770337868 -0.384797629
## [538,]  0.664816782 -0.4952302847 -0.578224175  0.2634443771  0.299110655
## [539,] -0.458713646  0.5591542720  0.483950802 -1.0712172096 -0.321584546
## [540,] -0.391631186 -0.5494563493  0.953941633  0.0364970323  0.890138666
## [541,] -0.459932233 -0.8716409253  0.133864842  0.2918316525  0.533705303
## [542,]  0.266156193 -0.2189951786  0.061736966  0.4096515445 -0.229038048
## [543,]  0.344308231  0.2851593715 -0.174263087 -0.3021703935 -0.091722354
## [544,]  0.754494648  0.4561970056  0.339310370 -0.0022268022  0.118843048
## [545,]  0.378936346  0.4402644382  0.317526133  0.1310562140  0.477112943
## [546,]  0.365464087  0.4277763898 -0.006784619  0.5236760757  0.051723764
## [547,] -0.337592217 -0.0267608899  0.312776967  0.1747521872  0.025219973
## [548,] -0.043766957 -0.1056845291 -0.298157590 -0.3004703745 -0.194792207
## [549,] -0.048982818  0.3764808300 -0.195677690 -0.3816380198 -0.193683020
## [550,] -0.110930947 -0.4798931054  0.136682319 -0.0916403900  0.237267418
## [551,]  0.128935162 -0.0436164575  1.049012602 -0.3209498675 -0.116741765
## [552,]  0.349763750  0.7505424152  0.143475685  0.4511670949 -0.048829098
## [553,]  0.644600706  0.4766294202  0.237775205 -0.1124291332 -0.046746718
## [554,]  0.301796214  0.7442879709  0.302072874 -0.5137654154 -0.141810425
## [555,]  0.098400188  0.3661140595  0.821460859  0.0887376200 -0.135310151
## [556,]  0.135366891 -0.1830112191 -0.252318027 -0.3284920680 -0.296758580
## [557,]  0.187702105 -0.8112516794  0.618198182  0.2062748530  0.180616703
## [558,] -0.372813857 -0.5775177218  0.713112793 -0.2595316849 -0.354395012
## [559,]  0.907324382  0.1933450191  0.452057650  0.4038191075  0.390851280
## [560,] -0.645197281 -0.3143226726  0.073104178 -0.2286369640  0.135232164
## [561,]  1.315903353  0.7410877051 -0.442232067  0.1623571454 -0.310794816
## [562,] -0.569745725 -0.5567515908  0.371393741  0.0059625202 -0.058401266
## [563,]  0.241409376 -0.1284484850  1.010978343 -0.5618115101 -0.980066745
## [564,]  0.747115186  0.5137902382  0.605723215 -0.9204421040 -0.160428761
## [565,]  0.062596180  0.1232334490 -0.051677832 -0.4039342494 -0.652176589
## [566,] -0.244588350  0.2225567578 -0.192467698  0.0155416535  0.069913471
## [567,]  0.839772720  0.0963880851  0.157279563  0.2854397183 -0.090917772
## [568,]  0.178471102 -0.6968480142  1.224117875  0.2185054033 -0.229389196
## [569,]  0.143967465 -0.1793386428  0.678300647 -1.1696954484 -0.217152272
##                 PC16          PC17          PC18          PC19          PC20
##   [1,]  0.7444607451 -0.2652373958 -5.490796e-01  0.1336499023  0.3452611113
##   [2,] -0.6482383131 -0.0171970719  3.180176e-01 -0.2473469895 -0.1140327429
##   [3,]  0.3248247158  0.1907506408 -8.789759e-02 -0.3922811953 -0.2043524231
##   [4,]  0.0513250859  0.4822096009 -3.584323e-02 -0.0267241008 -0.4643251074
##   [5,] -0.1524716533  0.1330252645 -1.869779e-02  0.4610302383  0.0654378154
##   [6,] -0.0127056581  0.1967133529 -2.972771e-01 -0.1297264835 -0.0711745335
##   [7,] -0.0279433054 -0.3200829050  1.230170e-01  0.0035239593 -0.0444495512
##   [8,] -0.3365097518  0.1614215017 -4.908981e-02  0.2196830773 -0.0106331412
##   [9,]  0.5070582930  0.2854754597 -2.870772e-01 -0.1822709687 -0.0197682471
##  [10,] -1.1318257248  0.7584688292 -2.387387e-01 -0.1275685149  0.1779240553
##  [11,] -0.0138706093  0.2849159741 -6.134944e-02  0.1720437193  0.0937289351
##  [12,] -0.0187810714  0.1611055355 -4.159689e-01 -0.1367793291  0.0566814179
##  [13,] -0.2920952462  0.0531727295  9.339577e-01  0.9728881275 -0.3157956887
##  [14,] -0.1992780260  0.0096995090  9.339247e-02  0.1010674465  0.1967267792
##  [15,] -0.1618282348  0.1754310229  2.238806e-01 -0.0531840832  0.3639545281
##  [16,] -0.6382781617  0.1798611136 -1.718454e-01  0.0906929739 -0.2822197817
##  [17,]  0.2443739278 -0.0458383708 -2.208124e-01 -0.0808510853 -0.1668401722
##  [18,]  0.2215767406 -0.0781818510  5.021716e-02  0.3243354151  0.1355909907
##  [19,] -0.1393548032 -0.6855739616 -2.705080e-01 -0.4576544799 -0.0261720852
##  [20,]  0.1209221166 -0.1193080949  1.076572e-01 -0.0023196540  0.0627784940
##  [21,] -0.1439936507  0.2273189096 -9.075712e-02  0.1205914711  0.1354815837
##  [22,] -0.2156163397  0.0416265799 -4.312105e-02 -0.2850057948 -0.0664739762
##  [23,]  0.0779077052  0.0516753915 -1.351681e-01 -0.2505840594  0.2833238390
##  [24,] -0.1695420732 -0.5795650326 -1.524509e-01 -0.4622425441  0.2441235537
##  [25,]  0.2252070093 -0.9343378255 -4.239600e-01 -0.2004324503  0.0316699323
##  [26,]  0.5428895558 -0.2315565339 -9.462169e-02  0.1754609443  0.1261898383
##  [27,]  0.0290689442  0.4558248771 -1.573099e-01 -0.2028349509  0.3681010830
##  [28,] -0.2633107617 -0.0230320660  5.164379e-02  0.3674136487  0.0390322000
##  [29,]  0.3507423311 -0.2024818286 -5.140403e-01  0.1407887067  0.1935393255
##  [30,]  0.0540947447  0.0555750576 -6.736093e-02  0.2280003716 -0.2726557691
##  [31,]  0.3051862215 -0.1875623435 -1.935028e-01  0.2018598204  0.0776311316
##  [32,] -0.6162327985  0.1233210520 -5.884654e-01  0.1115639655 -0.2376973065
##  [33,]  0.5443556733 -0.1853860373 -2.905819e-01 -0.1327205151 -0.3102765519
##  [34,] -0.6799791601 -0.0524136346 -1.278924e-01  0.3484526710  0.0977244882
##  [35,] -0.2649508034  0.5116666688 -5.148992e-01 -0.0449359045  0.1396499273
##  [36,]  0.3963311465  0.3424367694 -2.523528e-01  0.5088120277 -0.0182262570
##  [37,] -0.1353052207  0.1325066667 -1.212405e-01  0.1760177562 -0.0783161394
##  [38,] -0.4865692197 -0.0171701023  9.749344e-02 -0.3466943841 -0.0311932418
##  [39,] -0.5775705797  0.6852634929 -6.832692e-01  1.0176759372 -0.5936297787
##  [40,] -0.2486170983 -0.3725864432  4.074237e-01 -0.2392380729  0.0653398462
##  [41,]  0.0858440131  0.0154061997 -1.124179e-01 -0.2063437638  0.1529980089
##  [42,]  0.4138240100 -0.1707322382  3.545141e-01 -0.0644683713  0.0680433928
##  [43,] -0.1168940426 -0.5396200806  3.638398e-02  0.1722399585 -0.3325881394
##  [44,]  0.2139096807  0.0237139886 -2.109543e-01  0.0982275226  0.0303717372
##  [45,]  0.3840819798  0.2459056676 -1.469466e-01  0.0157458771 -0.0966009077
##  [46,] -0.0516728726 -0.3229228398 -8.174019e-03  0.1334369447 -0.1998283033
##  [47,]  0.4341320342  0.0058211607  8.968932e-02 -0.2077530623  0.0078418173
##  [48,] -0.0343499856  0.1432864234  1.566433e-01 -0.2386347890 -0.2403366743
##  [49,]  0.0675974293 -0.1890272279  8.181192e-03  0.2854018034  0.0309365297
##  [50,]  0.1742017650  0.0643542582  5.355821e-02 -0.2002754121  0.2156803986
##  [51,] -0.0583889171 -0.0825241914 -1.534190e-01  0.0859253386 -0.0634891959
##  [52,]  0.0267599697  0.2211230693  1.393874e-01  0.0785551072  0.0905176134
##  [53,] -0.1451536668 -0.0455372106  7.295476e-02 -0.0932288239 -0.0218792424
##  [54,]  0.4610520393  0.0023119228 -2.167759e-02 -0.0116195406 -0.1570539642
##  [55,] -0.0273991255 -0.1756512312  2.032964e-01 -0.0520325983  0.0649106633
##  [56,] -0.0455436441 -0.0730332412 -1.409306e-01 -0.0752782585  0.0300697515
##  [57,] -0.0136346681 -0.2686278403 -3.472606e-02 -0.2406998187  0.0511072884
##  [58,]  0.0076276816  0.4698692126 -4.504667e-01 -0.3869577956 -0.1062390440
##  [59,] -0.2005621445 -0.2045630549 -1.277670e-01  0.2367277317  0.0578713266
##  [60,]  0.2370915417  0.0415790617  5.176941e-01  0.1482043271 -0.4564661004
##  [61,] -0.5946048047 -0.5785348079  1.139374e-01  0.0079325268  0.2453309910
##  [62,] -0.1743616455 -0.0787539271 -1.120703e-01 -0.0880295467 -0.2495215707
##  [63,]  0.1448061468 -0.4050970648  6.565549e-02  0.2559123023 -0.4289500187
##  [64,] -0.0842293958 -0.3369495728  2.902474e-01 -0.3645193658 -0.0218847216
##  [65,]  0.2644121106 -0.3189750634  1.006240e-01  0.0343908745 -0.1639586428
##  [66,]  0.4712897357  0.1030461736  5.156184e-02 -0.0435454461  0.0120385599
##  [67,]  0.0720499724  0.2325538744  1.455717e-01 -0.0720682257  0.0790225044
##  [68,]  0.2757212862 -0.2805237812  1.404927e-01  0.0372159025  0.0833649877
##  [69,] -1.0626005498  0.1850617241 -1.347993e-01 -0.2668952190 -0.3814350912
##  [70,] -0.1078434849 -0.1246143671 -1.511215e-03 -0.0201171368  0.0939379250
##  [71,]  0.0723592874 -0.3383160278 -3.527509e-01 -0.0525835369 -0.0289468771
##  [72,]  1.4898419365 -0.3943927763 -4.943103e-01 -0.2226188045 -0.0047807310
##  [73,] -0.7025900371 -0.3233144668 -2.690081e-01 -0.2103448772  0.0834048136
##  [74,] -0.2314069611 -0.1111854157  4.271094e-02  0.0376418646  0.0935975116
##  [75,]  0.0555184949  0.0419709202 -1.141890e-01 -0.1821769894 -0.0116456811
##  [76,]  0.1968371132 -0.2604316743  5.447432e-03  0.2750953606 -0.1701957699
##  [77,]  0.0605687046 -0.1926071856 -3.781177e-01 -0.2349473090 -0.0699485241
##  [78,]  0.2213986609  0.2564393586 -8.694054e-05 -0.0296330599  0.2318213569
##  [79,] -0.1022416133 -0.4371565117  6.541248e-01  0.6232020130  0.6572255334
##  [80,] -0.0569375771  0.0933913214 -6.405911e-02  0.1272588554  0.2678163105
##  [81,] -0.1250507711  0.1965686827 -1.543090e-02  0.1643745864  0.0671390460
##  [82,]  0.1507082688  0.0460500757 -8.528589e-02 -0.0424911087  0.1097945421
##  [83,]  0.2951609043 -0.0727220045  3.850636e-01  0.2975862961 -0.1296675824
##  [84,]  0.8991911377  0.0740975033  2.824389e-01 -0.1775032259 -0.7876402180
##  [85,]  0.0541482024 -0.0050063011  8.935649e-02 -0.0258646039  0.0514446563
##  [86,]  0.0009987429  0.0807178300 -6.507399e-02  0.1604381362 -0.1529082400
##  [87,] -0.0404448228 -0.0343789127  2.292535e-03  0.1457468888  0.0364090961
##  [88,] -0.2263974440  0.0179289429 -5.487216e-01  0.0108520428 -0.0715637035
##  [89,]  0.0511789943  0.0131852725  2.283625e-01 -0.0381883962  0.0471079514
##  [90,]  0.0248136798  0.0233371930 -2.172770e-01 -0.1129248347 -0.2643933655
##  [91,] -0.1835520312 -0.0073079751  6.880183e-02  0.0569711434  0.1014561762
##  [92,] -0.0532671413  0.0115876931  1.149955e-01 -0.2499336883 -0.0463034074
##  [93,]  0.3440552885 -0.2273752521 -1.922491e-01 -0.0781472448  0.2033479975
##  [94,]  0.0633872491  0.0310541348 -5.257572e-02  0.1152561678  0.1769926531
##  [95,]  0.3622171113 -0.3077571762 -1.249274e-01 -0.0092797913 -0.0162603868
##  [96,] -0.1499599397  0.1836067507 -1.656348e-01  0.0902312461  0.0175660697
##  [97,] -0.6014543270 -0.0610520777  4.088117e-02 -0.1833302668 -0.0604185139
##  [98,] -0.0996387794  0.1457218445 -4.086137e-01 -0.0517074621 -0.0903242792
##  [99,]  0.2297949692 -0.1010915701  3.228795e-01  0.0795964606 -0.2354725917
## [100,]  0.0263312435  0.0738390906  2.193437e-01 -0.0561248044  0.0934256201
## [101,]  0.2603574888 -0.0843126026 -3.760217e-01 -0.1282177279  0.1466945932
## [102,] -0.0648161007 -0.0743586672  6.001312e-02 -0.1605585403 -0.1381556177
## [103,]  0.3166072907  0.1782153925  1.222033e-01 -0.1914123729  0.1774645649
## [104,]  0.1904717597 -0.2912688556  3.675219e-01 -0.1108806079  0.1781375653
## [105,] -0.3723552575 -0.2544929562  7.295163e-02 -0.0412255879  0.0550120885
## [106,] -0.3423285309  0.0370571626 -3.073614e-01 -0.1802702994 -0.1095713573
## [107,]  0.0260291585  0.0416980798  1.873460e-01  0.0537284809  0.0987456977
## [108,]  0.3955030905  0.3233273965  2.988237e-02 -0.0777973821  0.0970946107
## [109,]  0.4535034431 -0.3193808862 -3.373791e-02 -0.1463574077 -0.6693950389
## [110,]  0.2303559150 -0.2079807983  5.509481e-01  0.3335341685 -0.3083514381
## [111,] -0.1147786362 -0.2432508051 -1.125072e-01 -0.0451754187 -0.0888126673
## [112,] -0.0914461903  0.2412463437 -1.459792e-01 -0.1100026847 -0.0896473479
## [113,]  0.5978782675 -0.1822196905 -2.997565e-02  0.3190458027  0.4277165587
## [114,] -0.3616205824  0.2327580071 -2.695597e-01 -0.1740128225  0.0009258643
## [115,] -0.1170660795  0.1141917260  2.787614e-01 -0.2699318125 -0.4862268924
## [116,]  0.0181444217 -0.1943937215  2.229841e-01  0.1106013071 -0.1943231201
## [117,]  0.0188024294  0.3540363209 -5.535981e-01 -0.1880082735 -0.1775926041
## [118,]  0.3784407497 -0.3282198389  2.854566e-01  0.1676563450  0.1316948737
## [119,] -0.3174913261 -0.3551554039  1.613097e-01  0.0770344109 -0.3060738877
## [120,]  0.0741606002  0.1293691405 -9.533673e-02  0.1598354031  0.1444500222
## [121,]  0.3232157136 -0.0498534052  3.256012e-01  0.0859633989 -0.1910126392
## [122,] -0.1508543945 -0.0571332361  2.183625e-01  0.0936904685 -0.0794546001
## [123,]  0.8654238320  0.7210245200 -2.842764e-02 -0.1805240610 -0.1953916687
## [124,] -0.0786214283  0.1112746213 -2.389655e-02  0.0003689045  0.0938018536
## [125,]  0.1787431134 -0.0528239193  9.687076e-02 -0.1321926180  0.0656264988
## [126,] -0.2137144308  0.0204290791  4.576725e-02  0.1421019311  0.0844834024
## [127,]  0.1945433447 -0.0616013058  1.201657e-02  0.0727533344 -0.0556195344
## [128,] -0.4075855406 -0.1063572544 -4.203945e-02  0.1864270776 -0.0899024211
## [129,]  0.1487266791  0.0365407567  7.118367e-02 -0.0460559372  0.2878951781
## [130,]  0.1997560730  0.1643581615 -1.386212e-01 -0.2355432488 -0.0786941556
## [131,] -0.0321454015  0.1803153879  1.446663e-02  0.0537012203 -0.0672121974
## [132,]  0.2690891739 -0.4026752272 -1.168613e-01  0.0558655115  0.0581974748
## [133,]  0.1883770526 -0.0015159215 -7.463528e-02  0.2371738070  0.2597497358
## [134,]  0.1255354782  0.0181058265  5.293830e-02 -0.0645255704  0.1452601843
## [135,]  0.0498471273 -0.0348003591 -1.552902e-03  0.3088338323 -0.1359873769
## [136,]  0.1514154715  0.1551834702  1.691757e-01 -0.0013782678 -0.0002043019
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## [498,]  0.3028308700  0.1781680304 -9.454086e-04 -0.0391171702  0.0452046506
## [499,] -0.2458954590 -0.0950845250  8.196982e-02 -0.0281701607 -0.1726967460
## [500,] -0.1178393087 -0.0117894072  1.272862e-01  0.0101121466  0.0908039604
## [501,] -0.0971088399  0.1849624673 -1.226702e-01  0.0608150700  0.0748990612
## [502,] -0.0731260646  0.0669510233  3.999921e-01  0.2900773883 -0.0053964739
## [503,] -0.2466572140 -0.0012957265  1.336005e-01  0.0965700290  0.1928583877
## [504,] -0.3891070161 -0.0692886438 -4.328159e-01 -0.0792224197 -0.1311026627
## [505,] -0.4989273290  0.0614426403  1.472576e-02 -0.0052089236  0.1871894308
## [506,]  0.1061688558  0.1450975453  1.952681e-01  0.1988225061  0.3483613390
## [507,] -0.5869003919 -0.0713984513  1.147645e-01 -0.0515120701  0.0833758506
## [508,] -0.4477928280  0.2116429077  1.901902e-01 -0.1937817362 -0.0831327797
## [509,] -0.4326986916 -0.0421231224  4.042337e-01 -0.0714777001 -0.0411972178
## [510,]  0.0811069349  0.1173216262  2.709368e-01 -0.0068353403  0.1695494454
## [511,] -0.0251036033  0.1275815587  7.160374e-03 -0.3158463077  0.0718202346
## [512,] -0.1656525129 -0.0253422903  1.276502e-01  0.0321720287  0.0174672338
## [513,]  0.1002469618 -0.0122560627 -3.978731e-02 -0.1399808860 -0.1245712341
## [514,]  0.0337297517 -0.1151432061 -2.808120e-01  0.1177171098  0.0119567274
## [515,]  0.0430813394 -0.1123016706 -2.662367e-02  0.0242755669  0.0858319996
## [516,]  0.0036030549 -0.0917038623  1.850439e-01 -0.1336185270 -0.0104974251
## [517,]  0.1917801920  0.0156821488 -6.479661e-02  0.0497413311 -0.1812578717
## [518,] -0.5242638655 -0.1324175078  4.164366e-02  0.1739884378 -0.2905878805
## [519,] -0.0403973202  0.0983046405 -1.417744e-01  0.1817929811  0.2574283017
## [520,] -0.2654299713  0.0557073790 -4.489172e-02  0.2980716460  0.1251235465
## [521,] -0.5662658617  0.0688884138 -4.355084e-02 -0.0827461636  0.0817261030
## [522,] -0.1930575838  0.1638605084  1.696156e-01  0.0564170440 -0.0405222312
## [523,]  0.0367359627  0.2271729812  9.887981e-02 -0.0959645408 -0.0860998270
## [524,] -0.1157537076  0.1773029044  2.921844e-01  0.0806429725 -0.0289322155
## [525,]  0.3472701757  0.1286726709  4.361274e-03 -0.0003997164 -0.0658280590
## [526,]  0.0997620180  0.1237155150  3.308483e-01 -0.1543674922 -0.2362715510
## [527,]  0.1779140177  0.2259259121  1.293641e-01  0.2521963074  0.0172741437
## [528,]  0.4493965033  0.2358398169  2.839421e-02 -0.1211408420  0.0401779785
## [529,] -0.4918703631  0.3934087720 -2.733424e-01  0.0808508482 -0.3937157839
## [530,] -0.1573548181 -0.0332560589  4.103334e-02  0.1527013574 -0.0954426500
## [531,]  0.2357778568  0.1714303720 -1.682333e-01 -0.0480760651 -0.0048463579
## [532,]  0.0664241146 -0.0049832053  2.166153e-01  0.1474758498  0.0376285657
## [533,] -0.0589653404  0.1378144328 -5.111800e-02  0.1123664221 -0.0998720750
## [534,]  0.0011489071  0.1106196364  1.793498e-01  0.0120397051 -0.0228969758
## [535,]  0.1671650757  0.1637494512  2.267327e-01 -0.2011274932  0.0996771994
## [536,]  0.2236113177 -0.0556410397 -1.201821e-02 -0.1633614569 -0.0988305409
## [537,]  0.1441660514  0.0503790828  7.972177e-02 -0.0689864988  0.1948700448
## [538,] -0.1845235859  0.2560471166  2.157609e-01  0.0185852693  0.1565496905
## [539,]  0.2246393773 -0.0759854108 -2.144004e-01  0.1077679119 -0.0754591770
## [540,]  0.1157153017 -0.0946085126  5.607015e-01 -0.1632070601 -0.4108193773
## [541,] -0.0562823823  0.1692280446 -1.213046e-02 -0.0535534599  0.1078587734
## [542,] -0.1524138427 -0.0391271728  1.677550e-01  0.1610284957 -0.1314182663
## [543,] -0.2181697442  0.0270419575  7.676963e-02 -0.0335181090  0.1858465398
## [544,]  0.1223984599  0.1891922492 -3.446057e-02 -0.2263650827  0.0703565400
## [545,] -0.4367745068  0.0792966644  1.675768e-01  0.2307348371 -0.0359430593
## [546,] -0.0494701048  0.0013069407  4.558326e-02 -0.0629478688 -0.1050644118
## [547,]  0.0091468550  0.0290324891  1.488410e-02  0.0181300769  0.0288337616
## [548,]  0.2476202326 -0.1276536694  4.694131e-01 -0.2003872236 -0.0195139777
## [549,]  0.1388873508 -0.0515030353 -4.852651e-02  0.0264827985  0.1271702623
## [550,]  0.0847374464 -0.1500183423 -7.870783e-02  0.3579268358 -0.1824970475
## [551,] -0.0103802678 -0.3204581803 -9.803317e-02  0.0202986827  0.0295470955
## [552,] -0.0057459625 -0.0405914791  6.431842e-02 -0.3217160263 -0.1685804913
## [553,] -0.0573291350  0.0452087235  1.212636e-01 -0.0765829801 -0.0502932900
## [554,] -0.4351182523 -0.1917622682 -1.571844e-01 -0.2947566845  0.1635577852
## [555,]  0.0048691691 -0.0303433227  8.876475e-02  0.0041081275 -0.1145334139
## [556,]  0.0206805941  0.1334742843  1.145619e-01 -0.1800354098  0.1188747634
## [557,] -0.2612530693 -0.0405031771 -1.773446e-01 -0.2615734828 -0.0134633024
## [558,]  0.1100555556 -0.2497956869 -4.510752e-01  0.2787558115 -0.0588049466
## [559,] -0.1194566710  0.1244195792  1.484120e-02  0.0607378108  0.0576588492
## [560,]  0.2761350539  0.2273597903 -6.871634e-02 -0.0276269369  0.1478646421
## [561,] -0.1693243274  0.0815532304 -2.099437e-02  0.0818645399  0.2514566080
## [562,]  0.1807754237  0.0762688515 -3.325661e-01  0.0845524505 -0.0415106978
## [563,] -0.8029651181  0.1220605895 -4.950476e-01 -0.1819617089  0.3143066179
## [564,]  0.0098729574 -0.0800009784  6.354433e-02  0.5562492156 -0.1554353516
## [565,]  0.1475121301  0.3479599809 -1.950425e-01 -0.2460983953 -0.4040909029
## [566,] -0.1380625998  0.2932365347 -1.089496e-01 -0.1823602477 -0.2297445474
## [567,] -0.2324439379 -0.0655571760  2.108950e-02 -0.0419829133 -0.0813483422
## [568,] -0.0609931700 -0.1683659911 -3.066037e-01  0.3102957595  0.1730640918
## [569,]  0.9204776932 -0.3045424620 -1.808133e-01  0.1889373346  0.1631105493
##                 PC21          PC22          PC23          PC24          PC25
##   [1,]  0.0964300446 -0.0687893946  8.444429e-02  0.1751022126  0.1508872943
##   [2,] -0.0772594939  0.0944953050 -2.175267e-01 -0.0112801927  0.1703603547
##   [3,]  0.3107932463  0.0602560125 -7.422581e-02 -0.1026714190 -0.1710076559
##   [4,]  0.4338116608  0.2030870644 -1.239955e-01 -0.1532947800 -0.0774275740
##   [5,] -0.1164424689  0.0176343316  1.393310e-01  0.0053271101 -0.0030593705
##   [6,] -0.0024001785  0.1010804263  3.344819e-02 -0.0028377493 -0.1222827647
##   [7,] -0.0497039122 -0.0909661524 -1.428548e-01  0.0801136391  0.2774169346
##   [8,]  0.0446160665  0.1312420402 -2.402675e-01 -0.0962489988  0.1953110200
##   [9,]  0.0956161490 -0.1961497958 -5.867294e-02  0.0884762672 -0.1302274924
##  [10,] -0.2564517862  0.7160864577  1.671813e-01 -0.2158422553 -0.1346590354
##  [11,] -0.1931514370  0.1797289643  1.239130e-04 -0.0661301394  0.1793508578
##  [12,]  0.0256613371  0.1785045463 -2.105003e-01  0.1707930257 -0.2775786245
##  [13,] -0.0212336227 -0.2717732995  8.302672e-01  0.5694022242  0.2050807032
##  [14,]  0.0536465611  0.2250613132  1.057031e-01 -0.0118578557  0.0109923447
##  [15,]  0.1057076291  0.0548565083  5.742781e-03  0.1230654885 -0.1363435633
##  [16,] -0.0751373662  0.0433461466  1.334490e-01  0.1175438173 -0.2497804016
##  [17,] -0.2344824832 -0.0800755365 -1.157460e-01 -0.0257880551  0.1982873357
##  [18,] -0.1000151185  0.2316735867 -1.000205e-01 -0.1851440561  0.2205773586
##  [19,] -0.0712281618 -0.3695846503  2.874512e-02  0.3278945116  0.1650638434
##  [20,] -0.0042437600 -0.0571347487  2.945411e-02  0.0927005896  0.0899440626
##  [21,]  0.1108892757 -0.1668964790  3.887662e-03 -0.0412016079 -0.0692929154
##  [22,] -0.0733857126 -0.0551410551  1.379913e-01 -0.0349132014 -0.2320428771
##  [23,]  0.1246145246 -0.2051975642 -7.854400e-02 -0.0946139362 -0.0752040336
##  [24,] -0.1903107396  0.1253718436 -1.521652e-01  0.1059576635  0.0372312067
##  [25,]  0.1055683715  0.1636112461  1.458986e-01  0.1809515336  0.2961245192
##  [26,] -0.0568217163  0.1071936741 -1.553465e-01 -0.0414444675  0.1546978225
##  [27,]  0.0163246146 -0.0141963492 -5.970130e-01  0.2221582674  0.0103514077
##  [28,] -0.1014472410  0.0490161400 -3.782756e-02 -0.2044090783 -0.0458583192
##  [29,]  0.0617522965 -0.2965392069  5.075293e-02  0.2219116625 -0.3516296603
##  [30,] -0.1913776215  0.0214862498 -2.929037e-01  0.1208650268 -0.1369103839
##  [31,]  0.0595587515  0.2771629842  1.088098e-01 -0.0532229335  0.1666814036
##  [32,] -0.1063311988 -0.2066568837  2.611420e-01 -0.1086780448  0.0057569554
##  [33,] -0.0434313811 -0.0112246042  5.029196e-02  0.0301623182 -0.1101463645
##  [34,]  0.6876197560 -0.0004074532  9.408438e-02  0.0229190936 -0.3765055802
##  [35,]  0.0504027758  0.2876283914 -4.554592e-02  0.0539289063 -0.0656662192
##  [36,]  0.4640921393 -0.3482940477  2.944944e-01 -0.1828347635  0.2537595842
##  [37,] -0.1467733578  0.0054986329  1.521665e-01  0.2579466860 -0.0797662411
##  [38,]  0.2840168766  0.0526557024  1.154075e-01  0.0203929562 -0.1382255860
##  [39,]  0.4043981179 -0.1406766632  1.049883e-01 -0.3703681389 -0.3094285067
##  [40,]  0.2089804524 -0.2310395766 -4.420531e-01  0.1221456978  0.2819915427
##  [41,] -0.1590984393 -0.1873591123 -2.090009e-01 -0.0034415007  0.0283145970
##  [42,] -0.3980497527 -0.0355253748  1.527768e-01 -0.0471781829  0.0878759905
##  [43,] -0.3945969239 -0.1220412364 -2.748425e-01  0.3141513454  0.0472694608
##  [44,]  0.1630859956  0.1050367727  3.885715e-03 -0.0553808770  0.1268753135
##  [45,]  0.2582180768 -0.0426767559 -1.132296e-01  0.1022532639 -0.0436430789
##  [46,]  0.3773317635 -0.4099228882  6.112855e-02 -0.1638481544  0.0315084953
##  [47,]  0.1342565409  0.0717443366  1.917410e-01  0.0754665502 -0.1670607979
##  [48,] -0.0787229144  0.0699699317 -1.751332e-01  0.0339290587  0.1451632870
##  [49,] -0.0133521503  0.0849026685  3.118708e-01 -0.0416129342  0.0848382565
##  [50,] -0.1320383548 -0.2447116610 -1.020497e-01 -0.0408257688  0.1336454037
##  [51,]  0.0627384666  0.0519012423  1.971663e-02 -0.0571482290 -0.0566535809
##  [52,] -0.0995524008  0.0506136205 -1.033791e-01 -0.0174916710  0.0681517454
##  [53,] -0.0226944882 -0.0777153343 -5.233978e-03  0.0142555107  0.0315474360
##  [54,]  0.0598975865  0.2370488144 -1.119402e-01 -0.2379359159  0.0182763438
##  [55,] -0.2251934371 -0.1844281082 -2.365515e-01 -0.0305737020  0.1680200050
##  [56,] -0.0017325648  0.0488467944  6.633714e-02  0.0877541039  0.0644744746
##  [57,]  0.1634300567 -0.0268306860  2.159026e-02  0.0340839741 -0.0399774989
##  [58,] -0.0745584302  0.2344677947 -2.199298e-01  0.0578311893 -0.0745571265
##  [59,]  0.0461711930 -0.0421999111  7.051093e-02  0.0089610843 -0.0368382481
##  [60,]  0.2243181689  0.0357424595  1.926741e-01  0.0159167480 -0.1321624635
##  [61,] -0.1276285922 -0.2168390477  3.310787e-02  0.0320732181 -0.1802871265
##  [62,]  0.1228232989  0.0935845279  8.347651e-02  0.1223396053  0.0212412139
##  [63,] -0.1224776291  0.0173214607  6.316631e-02 -0.2338617546 -0.2075594763
##  [64,] -0.0043481885  0.2195472743  7.874096e-02 -0.1788528772 -0.0661238760
##  [65,]  0.1426873130  0.2035075522 -1.279958e-02  0.1170282052 -0.0664023204
##  [66,]  0.0574284597  0.1462134084 -8.278082e-02  0.0568954322 -0.1247534684
##  [67,] -0.0525687765  0.0699194106  3.490344e-02  0.0562117068  0.0225352088
##  [68,]  0.0458313220  0.0615712021  2.847847e-02  0.0293938347 -0.0018518567
##  [69,] -0.0179672286  0.1239548335 -5.671419e-01 -0.1119284311  0.2249337178
##  [70,]  0.0321781929  0.0892493026  9.990179e-02  0.0548699108 -0.0126058236
##  [71,]  0.0571423282 -0.0830178567 -2.073762e-01  0.1006802771  0.0339903355
##  [72,] -0.3361399692 -1.1424568904  2.420656e-01 -0.3463345316 -0.2252647249
##  [73,]  0.1239360454  0.4460762715 -1.913596e-02  0.0131668390 -0.1545557510
##  [74,]  0.0737021390  0.2859701894 -2.018351e-01  0.0772917781  0.1152392295
##  [75,] -0.1092980597 -0.0138453481 -1.008081e-01  0.0156875207  0.0693816650
##  [76,]  0.1221939976 -0.0225916039 -2.905887e-02 -0.0714540887 -0.0684432765
##  [77,] -0.3405424686 -0.2764202951 -1.959324e-01  0.1177716340 -0.0839922418
##  [78,]  0.4881849266  0.4593568598 -1.759304e-01 -0.1091187680  0.0415840412
##  [79,] -0.3315363350  0.0917692151  7.817362e-02  0.1330530067  0.1694977343
##  [80,]  0.0368236653  0.0528781014 -1.414879e-02  0.0039337198  0.0950812029
##  [81,] -0.1542842180 -0.1093752122 -3.339722e-02 -0.1138734011  0.0679308746
##  [82,]  0.1350984499 -0.1334625335 -1.924447e-01 -0.2517763795 -0.2235888446
##  [83,] -0.0864821708  0.2665122626 -4.632589e-02  0.2608106914 -0.2015897382
##  [84,] -0.1196533997 -0.2956341346  2.224689e-01  0.5212444111  0.1096453749
##  [85,] -0.1733274117 -0.0378600041  1.204891e-01 -0.0638102799  0.0384329228
##  [86,] -0.1874953206  0.1106660926  1.144139e-01 -0.0347490130  0.0772104119
##  [87,]  0.0851120925 -0.0788800422  1.654986e-01  0.0521952944  0.2042659546
##  [88,]  0.1811405538 -0.1483353830  6.109776e-02 -0.3054586360  0.3391317681
##  [89,] -0.0855485818  0.0340156879 -7.278041e-02 -0.0125030575  0.0958176014
##  [90,] -0.1599179864  0.1334391692 -2.361823e-01  0.1056798233  0.0502431449
##  [91,]  0.0751970527  0.0804334005 -6.635577e-02 -0.1062624672 -0.0187054096
##  [92,]  0.0401375273  0.0237493296 -2.193603e-01 -0.0722681274 -0.0675405913
##  [93,] -0.1061390089  0.0371149157 -7.913824e-02 -0.0716357728  0.0325885709
##  [94,]  0.0279618710 -0.0009136168  4.019360e-02  0.0433231398 -0.0094418981
##  [95,]  0.2536049528 -0.3215360102 -1.098792e-01  0.0810358901 -0.0122471521
##  [96,]  0.0053144100  0.0796755233 -1.002077e-01 -0.2433959673 -0.0916256347
##  [97,] -0.0007498808 -0.0602166502  1.639304e-01 -0.1109289976 -0.2189383088
##  [98,] -0.0102439849 -0.0916181734 -6.026311e-03  0.0642046278  0.0182723018
##  [99,]  0.0655232802  0.1361721728 -2.380960e-02 -0.0848870016 -0.0354074807
## [100,] -0.2042063479 -0.0225011341 -1.597762e-01  0.0597491622  0.0990007411
## [101,] -0.2259323796 -0.1230114995  1.248698e-03 -0.1666755649  0.0778359909
## [102,] -0.0956354397 -0.0747250878  2.364517e-02  0.1296679865 -0.1440811607
## [103,] -0.3564485355  0.0251482825 -2.992479e-02 -0.0979259685  0.0047162894
## [104,]  0.0301399587  0.0335743414  9.970638e-02  0.1500637562  0.0644902797
## [105,]  0.0747135743  0.1185387392 -7.064032e-02  0.0494289954 -0.0067925146
## [106,] -0.1361272405  0.3722179590  1.186143e-01 -0.0347120679  0.4630159288
## [107,] -0.1355978998 -0.0423956441  1.032042e-01 -0.0462420781 -0.0124441010
## [108,] -0.0592468406 -0.2683180006 -1.795726e-02 -0.1103468343 -0.1032305687
## [109,] -0.3507692208 -0.0179928361  3.797596e-01  0.1684134918 -0.0805735130
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## [472,]  0.4132059354 -0.1253744570 -2.372379e-02  0.0689106194  0.0632012566
## [473,]  0.0801477782 -0.0994904279 -7.551916e-02  0.0231996252  0.1031441886
## [474,]  0.3744615653 -0.2166879487 -2.056099e-01  0.0225950366  0.1145355103
## [475,] -0.0028374238 -0.0024283917  3.394618e-03  0.1226650174 -0.0657781843
## [476,]  0.2074374506 -0.1946890651  8.574414e-02  0.0375255534 -0.0176623189
## [477,]  0.0077541911 -0.1691781741 -2.393995e-01  0.0235301019 -0.0142543889
## [478,] -0.1274779565  0.1059211446 -1.420760e-02  0.1274986616 -0.0504357570
## [479,] -0.1752435869  0.0647906068 -1.963559e-02  0.0512455781  0.1507897689
## [480,]  0.0741405793 -0.0683683718  3.014739e-01  0.1056563632  0.0291503627
## [481,] -0.2908519435 -0.0150945457 -3.992097e-02 -0.0606607864 -0.1823717944
## [482,] -0.1718005261  0.0776043939 -1.207006e-01 -0.0681632290  0.1262100777
## [483,]  0.1601295941  0.0931232896 -2.046626e-01  0.0663637286  0.1799645400
## [484,] -0.0492504351 -0.1541041794 -1.239617e-02 -0.1114961587  0.0304119543
## [485,]  0.1618240979 -0.1260922761 -4.885764e-03 -0.0695939217  0.0167158472
## [486,] -0.4459029701 -0.0955926343  2.079300e-01  0.4035059614  0.0203477558
## [487,] -0.1411106697 -0.0359464998  1.001449e-01 -0.0894683013 -0.0941013165
## [488,] -0.2558123584  0.0883016437  1.159603e-01 -0.1818387487 -0.0790781079
## [489,] -0.0136545293 -0.0515281909 -1.936755e-02  0.0442112419  0.1645016909
## [490,]  0.2669916390 -0.2670016650  2.284507e-01  0.0042597084 -0.0555873751
## [491,] -0.0535814976  0.0775740576  5.386731e-02  0.0309546385 -0.0198687085
## [492,] -0.1135163594  0.0475542839 -1.739836e-01 -0.1444633296 -0.0339643106
## [493,] -0.0602203735  0.0189780745 -1.063966e-01 -0.0105156590  0.0800763820
## [494,] -0.0687773666 -0.1016273418  3.828534e-02 -0.0499980530 -0.1182422028
## [495,] -0.1582220042  0.1122348479 -7.618847e-02 -0.0213837212 -0.0990125083
## [496,] -0.0283047989  0.0780852815  4.581743e-02 -0.0558049130  0.0260473433
## [497,]  0.3363330523 -0.0354564885 -7.149409e-02  0.0352965454  0.0652322179
## [498,]  0.1034776270 -0.1754064399 -6.651803e-02  0.0641182475 -0.0794539356
## [499,] -0.0481731383  0.1476443912 -2.255443e-01 -0.2411787219 -0.1401067009
## [500,] -0.3277170244 -0.0214895498  3.656111e-03 -0.0532268599 -0.0078440385
## [501,]  0.0437030758  0.0874188865 -1.731452e-01 -0.2215054214  0.0636572848
## [502,]  0.1413515432  0.3248988272  1.369943e-01 -0.1227243079  0.1005775264
## [503,]  0.0631491852 -0.1003537623  9.887905e-02 -0.1298086318  0.0183798448
## [504,]  0.0312549171 -0.1818324231  9.877624e-03  0.2570654313 -0.1507681423
## [505,] -0.1123521419 -0.2210885176  4.119637e-01 -0.1621171978 -0.0747037425
## [506,]  0.0311085932 -0.0043112438 -1.554371e-01 -0.1615159870  0.1462901120
## [507,]  0.0117125024 -0.3190203960  1.446060e-01 -0.2152535411  0.1095516050
## [508,] -0.0780488273 -0.0636343159  3.972090e-03  0.1126306367  0.0411398608
## [509,]  0.0986046838 -0.0827229223 -1.284032e-01 -0.0343611021  0.0523426687
## [510,] -0.1798850375 -0.1992963775  6.385868e-02 -0.0463180154  0.0313154612
## [511,]  0.0150364127 -0.0385701112  7.653051e-02 -0.1113571741  0.0360291268
## [512,] -0.0399284189 -0.0539012945  7.707678e-02  0.0558295772  0.0042648705
## [513,] -0.2665292246 -0.1931822640 -1.711874e-01  0.0110864948  0.1055062492
## [514,]  0.0088321206  0.0921322424 -1.336851e-02 -0.0527803820  0.0566613849
## [515,] -0.2238695921 -0.1543697584 -1.442546e-01 -0.1354297203 -0.0721716862
## [516,]  0.1858416020 -0.0891651817  5.090259e-02 -0.0673758027  0.0224514622
## [517,]  0.1810812819  0.0867360333  1.384049e-01 -0.1324629140 -0.0090377647
## [518,] -0.0396300818  0.0422971304  1.048030e-02  0.0496241700 -0.0785177188
## [519,]  0.0597489899  0.0732309633 -2.120701e-01 -0.0717921176  0.0189229270
## [520,]  0.0274380655 -0.0214256895 -8.224662e-02 -0.0195345168  0.1063930278
## [521,] -0.0741127018 -0.0905924637  1.342385e-01 -0.0470197036 -0.1108311481
## [522,]  0.0627752410 -0.0421343311 -1.723356e-01  0.0155013766 -0.0518260244
## [523,] -0.0824384780  0.0250013489  1.149064e-01  0.0039590058 -0.0546444196
## [524,]  0.0249831764 -0.1507464018 -1.414050e-01 -0.1099078444 -0.0255135349
## [525,] -0.0373629133  0.2096402441 -8.633648e-02  0.1116312807 -0.1001301363
## [526,]  0.0838390278  0.1079865972  3.450158e-02  0.1719735169  0.0591756828
## [527,]  0.3318483108 -0.2947450685 -1.906989e-01  0.0550575235  0.1471686399
## [528,] -0.0007428400 -0.0794869253 -9.811836e-02  0.0489272789 -0.0264873014
## [529,]  0.3705852161 -0.0223391489  5.075365e-01  0.0399525672 -0.1697663841
## [530,]  0.1250829277 -0.0366604171  4.389193e-02 -0.0069134401  0.0520789685
## [531,] -0.2510653323  0.0340772274 -8.753856e-02 -0.0982485755 -0.1114855027
## [532,]  0.0047666490 -0.0781373344  7.655868e-02 -0.0380683743 -0.1246895793
## [533,]  0.1415752357 -0.1501413208 -1.183314e-01  0.0132847088  0.1539406806
## [534,]  0.1023467340  0.1517558697 -1.320795e-01 -0.2665377512 -0.1282250448
## [535,] -0.0025279486  0.1124682587 -1.477884e-01  0.0405273999  0.0306409909
## [536,]  0.0791481775 -0.0502756205 -2.639892e-01 -0.0744509737  0.0008455486
## [537,] -0.2740650665 -0.0002925086  1.707404e-01  0.1095625155  0.0994614805
## [538,]  0.2606428739 -0.1601463771 -1.178442e-01  0.0390099169  0.0633318332
## [539,] -0.0413794118 -0.0604094030 -2.811241e-02  0.1403114024 -0.0330961759
## [540,]  0.1154812600  0.2581934783 -7.793227e-02 -0.0711976819  0.0410671686
## [541,]  0.1535435455  0.0239799396 -8.839128e-02 -0.1178975803  0.0735661058
## [542,] -0.0679373594 -0.1118336346  1.683499e-01  0.1715550493  0.0572524009
## [543,]  0.0110374761 -0.1705246655 -5.717170e-02 -0.0128147660  0.1232452688
## [544,] -0.0656376005  0.0115407705 -1.397186e-01 -0.0441481701 -0.0402201549
## [545,]  0.0641597728 -0.0257372276 -1.306238e-01 -0.0130286164  0.0536290674
## [546,]  0.1105362335  0.0476875761 -8.635963e-02 -0.0603229788  0.0296765078
## [547,] -0.0262990959  0.0723866365  1.742109e-01  0.0600842055 -0.0903222486
## [548,]  0.0494065172  0.0747923167  1.121067e-01  0.0931615209 -0.0064837083
## [549,]  0.0420616613  0.1434447978  2.151116e-01  0.0669104550 -0.0548411936
## [550,]  0.0732487201  0.0198345047 -9.193927e-02 -0.0172044830 -0.0976366593
## [551,] -0.0119356005  0.0136962943 -1.528663e-01  0.0443186800  0.0072493585
## [552,] -0.0388647303 -0.0294327168 -1.437595e-03  0.0211029594 -0.0051501501
## [553,]  0.0994771923 -0.0523366815 -3.192496e-03 -0.0208073885 -0.0508996216
## [554,]  0.1162426476  0.0972882879  7.659123e-02  0.1633788667 -0.1343697535
## [555,]  0.0389261142  0.0150285734 -2.689412e-02  0.0451796495  0.0452185715
## [556,]  0.3942051539  0.1442763873  7.512395e-02  0.1142014279  0.1297250296
## [557,]  0.2658959188 -0.0852756994 -1.773711e-02  0.0573839788  0.0860394792
## [558,]  0.2548848500 -0.1344057649 -2.695888e-01  0.1253596547  0.1409818413
## [559,]  0.0974032157 -0.0506046046  4.281686e-03  0.0074148594  0.1833745030
## [560,]  0.0104818333 -0.0097405680  3.344908e-02 -0.0084439272  0.0371458564
## [561,]  0.0720893347  0.0359652007  4.155828e-02  0.0841586957  0.0655886608
## [562,]  0.6438555162 -0.1160958384 -1.348357e-01  0.0778267477  0.2155456879
## [563,] -0.3366411323 -0.5256708725  4.037840e-01 -0.2315981974 -0.0744296594
## [564,] -0.2819119524 -0.0637883885  3.027516e-01  0.3971743169  0.1344740836
## [565,]  0.0068818177  0.0669407679  8.851262e-02 -0.1078034921 -0.2193267810
## [566,] -0.0097931016 -0.0195459671 -5.535634e-02 -0.0860588433 -0.0011958031
## [567,] -0.0365600992 -0.0632967943 -2.001358e-01  0.0447797442 -0.0024266219
## [568,]  0.1405238587  0.0424409640  1.686715e-01  0.1957966922 -0.3774982893
## [569,]  0.2744382324  0.2430237050  3.788121e-02  0.0750448656  0.0174926193
##                 PC26          PC27          PC28          PC29          PC30
##   [1,] -0.2013263051 -2.523629e-01 -3.388464e-02  4.560759e-02  4.712774e-02
##   [2,] -0.0410926274  1.811108e-01  3.259550e-02 -5.682424e-03  1.866234e-03
##   [3,]  0.0047312486  4.952586e-02  4.698448e-02  3.143131e-03 -7.498749e-04
##   [4,] -0.2749828222  1.833008e-01  4.244698e-02 -6.923387e-02  1.991989e-02
##   [5,]  0.0392197801  3.213957e-02 -3.475564e-02  5.033481e-03 -2.119512e-02
##   [6,] -0.0302723330 -8.438081e-02  7.296587e-04 -1.970400e-02 -3.456433e-03
##   [7,] -0.0267249755  2.074464e-02 -4.673321e-02 -1.296846e-02 -5.468279e-03
##   [8,] -0.0594137473  6.662113e-02  2.615274e-02 -2.859407e-03 -1.696347e-03
##   [9,] -0.0549994685  3.829073e-02  3.712728e-02  1.169858e-02 -5.276735e-03
##  [10,]  0.3108206873 -2.849340e-03  1.356126e-01  3.775496e-02 -3.823914e-03
##  [11,] -0.0011132902 -1.675329e-02 -1.787033e-02 -8.472303e-04  8.589286e-03
##  [12,] -0.0988438257 -5.025511e-02  1.672603e-02 -8.893782e-03 -2.264877e-02
##  [13,]  0.1544995990 -1.601695e-01  2.189479e-01 -4.168578e-02 -3.128057e-02
##  [14,]  0.0185216253 -6.094451e-03 -2.104929e-02  1.333681e-02 -5.901062e-03
##  [15,] -0.1817110172  1.686671e-01 -1.248878e-02  5.471581e-02  2.767104e-03
##  [16,] -0.0132177128 -1.545333e-01 -8.311679e-02  3.490813e-02 -4.127870e-03
##  [17,] -0.0741980103  1.496604e-02  1.660988e-03 -2.340097e-02 -1.378581e-02
##  [18,]  0.0998664510 -7.732604e-02  6.074890e-02 -9.698796e-03 -1.266565e-02
##  [19,]  0.0289918326 -5.273101e-02 -1.596623e-03  4.840404e-02  5.987472e-03
##  [20,]  0.0314450550 -5.423713e-02  9.789698e-03  7.673122e-03  1.840938e-03
##  [21,]  0.0355362005 -9.840364e-02 -1.503860e-02 -1.881974e-02 -1.131431e-02
##  [22,] -0.0038246508  4.633703e-02 -1.209599e-02 -6.511882e-03 -8.590024e-03
##  [23,] -0.1164538409 -2.216492e-02  1.015524e-03 -1.634073e-02  1.872530e-02
##  [24,]  0.0916050281  1.468242e-01  6.867301e-02  1.786932e-02  1.386952e-02
##  [25,] -0.0874379704 -1.431175e-01  3.447092e-03 -2.255543e-02 -3.999663e-03
##  [26,] -0.0677237649 -4.147013e-02 -2.951161e-02 -1.657229e-02 -3.178130e-03
##  [27,] -0.0357830509  6.090625e-02 -2.388746e-02  5.642173e-03 -1.339863e-02
##  [28,] -0.0483807591  7.474866e-02 -1.755439e-02  2.208178e-02 -8.553100e-03
##  [29,] -0.0463898691 -2.400501e-01 -1.852092e-01 -1.492340e-02  9.578804e-04
##  [30,]  0.0860853392 -1.294573e-01  1.125290e-02  3.714214e-02  2.014350e-03
##  [31,]  0.1964367931 -2.131927e-01 -9.860072e-02  2.126908e-02  1.608133e-02
##  [32,]  0.0582729648 -2.306134e-01 -1.768593e-01 -7.475334e-02 -1.128161e-03
##  [33,] -0.1339382974 -1.253022e-01  1.125350e-01 -4.434909e-03  1.886774e-03
##  [34,] -0.0291953182  4.075234e-02  1.254330e-02  1.420997e-02 -1.165588e-02
##  [35,]  0.0209466264 -2.240063e-02  4.957060e-02  5.795811e-03 -3.132503e-02
##  [36,]  0.0848362899  1.615390e-01 -1.339550e-02  3.934955e-02  3.490852e-03
##  [37,] -0.0342079425 -6.060832e-02 -1.122619e-01  6.738025e-02  1.370542e-02
##  [38,] -0.0875148451 -1.650241e-01 -3.219827e-02 -1.617018e-02  5.144779e-04
##  [39,]  0.1758886282  1.604604e-01  5.386968e-02  1.842240e-01  1.989133e-02
##  [40,] -0.1021726527  1.289034e-01 -7.427828e-02  2.945002e-02  2.146481e-03
##  [41,] -0.0714635560  7.019861e-02  1.158537e-02 -2.247350e-02 -1.566702e-02
##  [42,]  0.1507064526 -3.820128e-03 -4.882003e-02  2.547541e-03  2.308071e-03
##  [43,] -0.0097682136 -2.479041e-02 -7.096251e-02 -1.155836e-02  1.589353e-02
##  [44,]  0.0612412639 -1.019745e-01 -1.370845e-03 -7.961068e-02 -1.397809e-02
##  [45,] -0.0171718343 -4.877762e-02  1.425226e-02 -7.139958e-02 -1.085998e-02
##  [46,]  0.1332320422  1.573983e-02  5.422979e-02 -6.387622e-03 -7.213235e-03
##  [47,]  0.1425991752  5.474195e-02 -1.825670e-02 -2.922901e-02 -2.649774e-03
##  [48,]  0.0028553147  1.498919e-02  1.783116e-02  3.335616e-02 -1.785149e-03
##  [49,]  0.1324480590 -2.199369e-03  3.816358e-03 -1.275649e-02 -8.411835e-04
##  [50,]  0.0241950429  3.299221e-02 -8.502787e-03 -1.188563e-02 -2.865884e-03
##  [51,] -0.0209776680  6.139058e-02 -9.541691e-03  1.959516e-02  4.711585e-04
##  [52,] -0.0739111736  3.792347e-02 -1.418360e-02  2.929794e-02  7.270380e-03
##  [53,] -0.0893671777 -1.803353e-02  4.758468e-03 -2.715377e-04  1.642671e-03
##  [54,] -0.0606178187 -2.190753e-02 -4.764801e-02  3.402123e-02  1.303268e-02
##  [55,] -0.1075797759  1.268873e-01  2.923216e-03  1.113450e-02 -4.343678e-03
##  [56,] -0.0058355492  2.774052e-02  1.416855e-02  2.401521e-03 -1.940349e-03
##  [57,] -0.0722065369 -8.119004e-02  7.271206e-02  1.327148e-02  4.135286e-03
##  [58,] -0.1343191246  2.950093e-02  5.444365e-02  4.011741e-03  1.659040e-02
##  [59,] -0.0691174690  8.049384e-04  2.627152e-02  4.565142e-03  6.788361e-03
##  [60,]  0.0400160356 -1.686265e-02 -1.071847e-02  1.590382e-02 -6.883016e-03
##  [61,]  0.0568714092  7.112930e-02  8.806180e-03  1.288489e-02  6.812673e-03
##  [62,]  0.0788845808  2.201995e-01 -2.946023e-02 -1.562093e-02  5.269029e-03
##  [63,] -0.0098332379 -1.134152e-03  9.638361e-02  2.795349e-03 -1.901582e-02
##  [64,]  0.0335429502  5.289948e-02 -8.110426e-02 -1.615960e-02 -1.141707e-02
##  [65,] -0.0290360085 -1.228215e-01  9.356070e-03 -8.243027e-02 -4.849783e-03
##  [66,]  0.0465312637 -1.922755e-01  1.659535e-02  6.820462e-03  3.908128e-03
##  [67,]  0.0604134233  9.187789e-02 -1.975320e-02  9.282008e-03  5.559412e-03
##  [68,]  0.0761632336 -9.449785e-03  3.607516e-02  1.644550e-02  3.225830e-03
##  [69,]  0.2804283970 -2.445271e-02  6.842730e-03  7.394054e-03 -1.258908e-02
##  [70,]  0.0091579194 -5.251089e-02  1.240814e-02  1.391723e-02  6.642330e-03
##  [71,] -0.0668453796 -1.379328e-02 -4.034711e-02 -4.567540e-02 -1.497659e-05
##  [72,]  0.0533337084  1.533702e-01  2.941771e-02 -5.665631e-03 -1.872210e-03
##  [73,] -0.0797672858  1.517182e-02  8.814363e-02 -3.560637e-02 -2.146240e-02
##  [74,] -0.0717088123 -3.146387e-02 -4.010897e-02 -4.737433e-02 -9.918869e-03
##  [75,] -0.0169312595  5.540068e-02  3.076006e-02 -2.228666e-02 -2.118429e-02
##  [76,] -0.0026046375 -9.489266e-02  2.564001e-02 -5.653385e-04 -5.060816e-04
##  [77,]  0.0207984498 -1.733530e-01  5.676664e-02  3.943605e-02  2.590542e-04
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## [407,]  0.0397575699 -6.577997e-02 -1.047537e-02 -4.449056e-03  2.233120e-03
## [408,] -0.0514258563  4.647223e-02 -6.982733e-02 -9.503059e-05 -1.830162e-03
## [409,] -0.0501724842 -4.628722e-02  3.999780e-02 -3.429226e-03 -3.077484e-03
## [410,]  0.0276819728  5.915175e-02  1.304026e-02 -7.395440e-03 -9.302405e-03
## [411,]  0.0931085075  1.502863e-02 -2.917256e-02  1.907808e-02 -5.034972e-03
## [412,]  0.0361947758  7.667876e-02 -1.464209e-02 -1.024093e-02 -9.066808e-03
## [413,]  0.0759067705 -1.487671e-02 -3.355674e-02  5.460849e-03  4.758629e-03
## [414,]  0.0214399904  6.105112e-02  1.557195e-02  2.358897e-02 -9.245123e-03
## [415,] -0.0655598354 -5.033438e-02  8.129611e-03  2.045621e-03  1.321633e-03
## [416,] -0.0746638330  1.307785e-02  6.435182e-03  2.362431e-02 -4.456626e-03
## [417,]  0.0175872866  7.520778e-02 -1.593285e-02 -1.676901e-02 -9.105100e-03
## [418,] -0.2350128938 -8.670062e-02 -3.914007e-02 -8.412364e-03 -8.432469e-03
## [419,] -0.0649883309  5.130667e-03 -2.709725e-03  4.175096e-02  8.282799e-03
## [420,] -0.0269674710  7.789492e-02 -8.614982e-03  3.714081e-04 -1.767863e-03
## [421,]  0.0314217620 -9.322640e-03 -4.407198e-03 -3.730030e-03  2.946087e-03
## [422,] -0.1267276154 -5.979588e-02  4.329068e-02  3.301665e-03  7.386138e-03
## [423,]  0.1329104632  4.852279e-02  9.716654e-03 -1.071229e-02  3.466874e-03
## [424,]  0.0104490114  2.493918e-02  1.565607e-03  1.344292e-03 -5.307538e-03
## [425,]  0.1074844809  1.021646e-01  9.004209e-03  3.485728e-02  5.458774e-04
## [426,] -0.0292477139  5.384906e-03 -1.920644e-02 -1.169381e-02 -5.006225e-03
## [427,]  0.0259003372  5.924542e-02 -2.557271e-02 -1.590461e-02  1.477057e-04
## [428,] -0.0082500580  4.920727e-02 -3.965043e-02 -4.074290e-02 -7.762837e-03
## [429,] -0.0348530225 -5.545228e-02 -2.311797e-03  8.429576e-03 -3.407335e-03
## [430,] -0.0193629073 -7.837772e-02  2.252529e-02  4.875501e-03  1.622238e-03
## [431,] -0.1475480871  9.553901e-02 -2.979921e-02  2.354127e-02  1.319264e-02
## [432,] -0.0115217791 -6.659441e-02  2.476894e-02  2.398590e-02  1.137917e-02
## [433,]  0.1532951378 -5.665683e-02 -5.759966e-03  6.076942e-03 -3.174998e-03
## [434,] -0.1083129751 -2.767272e-02 -4.327756e-02 -3.395174e-05 -1.344549e-02
## [435,] -0.0482208081 -7.436367e-04  1.308840e-02 -1.374610e-02  7.539469e-03
## [436,] -0.1294928577 -1.084657e-02 -3.353187e-02 -1.871763e-02  2.204407e-03
## [437,] -0.0210502075 -5.057234e-03 -1.764138e-02  2.520620e-02  2.916394e-03
## [438,] -0.0469124386 -6.929138e-02  8.631832e-03  1.671611e-02  3.894420e-03
## [439,]  0.0030790549 -4.271941e-02 -1.261166e-02 -1.074337e-02  4.852833e-04
## [440,] -0.0346701254 -1.097738e-02  7.724959e-03  6.899361e-03  6.458380e-03
## [441,]  0.0828997283  7.055109e-03 -5.337323e-02  2.224083e-02  4.878054e-03
## [442,] -0.0055805568  8.821182e-03  1.382174e-02 -1.344243e-02  3.396704e-03
## [443,] -0.0729310386  3.407189e-02 -2.967962e-03 -7.760464e-03 -3.493852e-03
## [444,]  0.0177492855 -5.387709e-02  1.884810e-02 -4.802070e-02 -4.338005e-03
## [445,]  0.1562735762  3.150221e-03  4.466151e-03  4.862201e-03  1.930884e-02
## [446,] -0.0623633484 -4.012043e-02 -1.520601e-02  1.022661e-02 -1.006945e-02
## [447,]  0.0582232781  1.452520e-02 -1.925162e-02  2.865248e-03 -4.811615e-03
## [448,]  0.0128754184  2.673470e-02  2.146354e-02  5.440063e-03 -9.104536e-03
## [449,] -0.0849870024  2.708387e-02  8.849902e-03 -3.431193e-03 -6.911163e-03
## [450,]  0.2010218414  1.676424e-02  3.159649e-02  1.192446e-02  2.280731e-03
## [451,] -0.0086274992  1.100940e-02  2.657891e-02  6.812446e-05  9.958902e-03
## [452,]  0.0165258410 -5.186637e-02 -1.065244e-02 -1.348643e-02  1.141856e-02
## [453,] -0.0161773464 -3.190370e-02  8.514373e-03  2.434763e-03  1.629148e-03
## [454,]  0.0605699069 -1.478972e-01  1.379131e-03  1.947479e-03  1.131662e-02
## [455,] -0.0199151804 -8.535688e-05  1.231284e-02 -1.013423e-02 -9.981321e-03
## [456,]  0.0205975979 -1.980424e-02 -5.463217e-03  1.221674e-02 -9.874192e-03
## [457,] -0.0050881069 -2.604470e-02 -1.829845e-02 -1.097754e-02  4.368456e-03
## [458,]  0.0445463619 -5.794359e-02  1.048050e-02  7.872980e-03  7.710774e-03
## [459,] -0.0215768139 -6.829240e-03  1.931505e-02 -2.563659e-03  6.043094e-03
## [460,]  0.0704026997  5.492546e-02 -6.642672e-03 -1.111266e-02 -3.440349e-03
## [461,] -0.1744566135 -1.098756e-01 -6.305821e-02 -6.416242e-03  1.134838e-02
## [462,] -0.1128547170 -1.591164e-01 -7.982505e-02  1.200865e-02 -1.593339e-02
## [463,] -0.0497515406 -5.652857e-02  1.302232e-02  1.237799e-02  5.580899e-03
## [464,]  0.0274856355  3.604310e-02  7.760035e-03  1.815681e-02  4.941571e-03
## [465,] -0.0846326223 -1.595831e-02  2.824337e-02 -9.513276e-03  9.314585e-05
## [466,]  0.0915955060 -8.619147e-02 -9.496820e-02 -7.123957e-04  1.251121e-02
## [467,] -0.0349996388  1.225956e-02 -2.365618e-02  1.362756e-02  9.798245e-04
## [468,]  0.0542473407  1.309476e-02  8.900566e-04 -2.664801e-04  2.499374e-03
## [469,] -0.1457441362  7.226593e-02 -5.951642e-02  1.311257e-02 -3.413340e-02
## [470,]  0.0957538784 -3.485376e-02  2.750362e-02 -1.043926e-02 -6.172565e-06
## [471,]  0.0909946383  1.398598e-01  8.858450e-03  7.244742e-04 -1.250954e-02
## [472,]  0.0730814567  6.023963e-02  1.322804e-02  5.220342e-03 -9.310005e-04
## [473,]  0.0226017652 -1.609558e-02  2.644659e-02 -2.709195e-02 -6.915033e-03
## [474,] -0.1242840374 -5.698309e-02  3.319390e-03  5.876624e-03  6.378471e-03
## [475,]  0.0182447696  4.114275e-02 -1.661732e-02 -7.879829e-03  4.976152e-04
## [476,]  0.1375631124 -1.253250e-01  6.518456e-04 -1.097810e-03 -4.923167e-03
## [477,] -0.0829225760  7.105777e-02 -4.770183e-02 -6.996362e-03 -9.172107e-04
## [478,] -0.0827292480 -3.235318e-02 -1.469619e-02  7.414257e-03  5.606623e-03
## [479,]  0.0448464007  4.121335e-02 -2.359053e-02  2.794497e-02 -3.572364e-03
## [480,] -0.0495987508 -2.268418e-02  2.227878e-02  8.961678e-03 -8.038788e-03
## [481,] -0.0128831723 -1.410240e-02 -2.422196e-02  2.001356e-02 -1.799201e-03
## [482,] -0.0381183878  2.857374e-02  1.498774e-03 -2.545113e-02 -5.760572e-03
## [483,]  0.0403505601 -2.930731e-02  4.188617e-02  1.191858e-02  3.348884e-03
## [484,] -0.0154989113  8.817212e-03  9.226792e-03  1.934553e-03  1.020699e-02
## [485,] -0.0136577142 -6.945356e-02  7.542745e-03 -1.162578e-02  1.376873e-02
## [486,] -0.0107779990  3.093484e-03  1.413849e-01 -6.100949e-03  1.202071e-03
## [487,]  0.0095431487 -7.376165e-03  2.000637e-02 -2.068873e-02 -5.432457e-03
## [488,]  0.0040869238  1.517483e-02  1.015079e-01 -1.262707e-02  3.374017e-03
## [489,]  0.0355692398  9.085520e-02 -4.393050e-03  4.668312e-03 -6.227434e-03
## [490,]  0.0086380352  1.069920e-02 -3.724756e-02 -2.337908e-02  9.673922e-03
## [491,] -0.0523983166 -2.155044e-02 -3.015589e-02  4.206849e-03 -4.615799e-03
## [492,]  0.0364243509  2.194271e-02  6.585056e-03 -5.260954e-03  1.175358e-02
## [493,] -0.0249186250 -9.840999e-02 -1.409311e-02 -4.124637e-03 -2.145734e-03
## [494,] -0.0546115161 -1.086523e-01  2.580461e-02  6.505626e-03  3.807495e-03
## [495,] -0.0900970424 -7.973081e-02 -1.382759e-02  2.391790e-02  2.493993e-03
## [496,] -0.0040977809 -6.976257e-02 -1.359450e-02 -7.869232e-03  4.008083e-03
## [497,]  0.0965211814 -5.682683e-02  6.498587e-03  1.456788e-02  2.151391e-03
## [498,] -0.0422754385  2.085169e-02 -1.607462e-03  3.798926e-03 -1.110263e-02
## [499,] -0.0967977019 -1.485310e-01  1.576602e-02  3.329348e-03 -9.341349e-03
## [500,] -0.0641045051  1.841422e-01 -7.024287e-02  1.970595e-02 -1.498247e-02
## [501,]  0.0854465362 -1.747535e-01 -3.607397e-02  1.867275e-03 -3.821167e-03
## [502,] -0.0963197757  9.104160e-02 -2.312398e-02  3.386630e-02 -1.529871e-02
## [503,] -0.0121822447 -1.090114e-02  8.724908e-03  4.694641e-03 -1.074887e-03
## [504,] -0.1180678238  2.658401e-01 -7.894180e-02 -2.561913e-02  7.697159e-03
## [505,]  0.1148367203  2.121193e-01 -3.514142e-02 -5.061458e-02  3.668640e-02
## [506,]  0.2752439895 -3.019773e-01  9.673065e-03 -1.996698e-02  4.151417e-02
## [507,] -0.0485533966  5.416690e-02 -1.649414e-02 -1.490646e-02 -2.155321e-03
## [508,] -0.0036376007 -1.802591e-01 -1.011343e-02  2.070820e-02  6.669538e-03
## [509,] -0.0647665350  4.842798e-03  1.594580e-02  9.613952e-03 -3.100001e-04
## [510,] -0.1754187549  1.359165e-01  4.067320e-02  5.041105e-02  2.144200e-04
## [511,] -0.0556837067  6.632740e-02 -6.746846e-03  1.531456e-02 -1.218153e-02
## [512,] -0.0984427406  1.808916e-02  1.255164e-02  9.930751e-03  9.221713e-03
## [513,]  0.0036057142 -8.355934e-02 -3.592810e-02  2.235170e-02  3.151072e-03
## [514,] -0.0112187011  2.530924e-02  4.763963e-03 -1.126705e-02  7.608210e-04
## [515,] -0.0091762716 -7.293476e-02  2.792662e-02 -3.556928e-03 -1.164186e-03
## [516,]  0.0038142602  3.300541e-02  8.325671e-03 -4.509973e-03 -1.285385e-03
## [517,]  0.0189855035 -9.752934e-02 -6.505096e-03 -2.312757e-03 -1.589520e-02
## [518,]  0.0550042618 -1.724436e-01 -9.894992e-02 -7.051032e-02  7.208234e-03
## [519,]  0.1580673727 -6.410352e-02 -8.250866e-03 -1.932592e-02  1.086353e-02
## [520,]  0.0544002611  1.580256e-02 -1.613705e-03  8.423291e-04  9.014139e-04
## [521,]  0.0074556575  9.663785e-02 -2.665164e-02 -3.072198e-02 -5.603826e-03
## [522,]  0.2131860543  1.741659e-01 -1.264691e-01  1.220225e-02 -8.726745e-03
## [523,] -0.0681589606 -9.361363e-03 -8.419239e-03  1.344440e-02  2.051314e-03
## [524,] -0.1061345671  4.966193e-03 -6.582652e-03  4.193781e-02  7.898565e-03
## [525,]  0.0664531179 -2.655619e-02 -2.136312e-02 -9.637608e-03  2.497448e-03
## [526,]  0.0886147194  1.155966e-01 -5.229288e-02  1.076846e-02  1.449954e-03
## [527,]  0.0330021360  8.336065e-02 -5.061548e-03  3.298927e-02  5.387830e-04
## [528,]  0.0181336410  4.282084e-02  3.040698e-02  1.508284e-02 -7.330015e-03
## [529,] -0.0934720894 -5.020254e-02  4.171083e-02 -7.809330e-03 -9.193665e-05
## [530,]  0.0288790490 -5.652693e-02 -1.947227e-03  1.611639e-03 -4.255828e-03
## [531,]  0.0424242869  9.025177e-03 -1.623234e-02  6.269355e-03 -8.871060e-04
## [532,]  0.0931826121 -3.654002e-02  4.324270e-03  4.165806e-03 -1.106227e-03
## [533,] -0.0830740552  1.658681e-02  1.150422e-02 -1.563064e-02 -6.663151e-03
## [534,]  0.1480707171  8.699232e-03 -5.961362e-02 -1.044751e-02 -6.141284e-03
## [535,]  0.0728753384  1.259825e-02 -9.518713e-03  9.373100e-03 -3.095154e-03
## [536,]  0.1536070303 -3.265112e-02  2.996697e-02  8.171708e-03 -3.458037e-02
## [537,] -0.0487762627  5.821042e-02  1.015633e-02  2.035367e-02  9.738559e-03
## [538,]  0.0329233687 -1.804282e-02 -2.169062e-02 -2.378939e-02  8.893677e-03
## [539,]  0.1468627182  7.253893e-02 -8.746899e-03 -1.161071e-02  9.286171e-03
## [540,]  0.1812441331  7.132198e-03  1.665571e-03 -5.739799e-02  3.679201e-02
## [541,] -0.0295036155 -8.523727e-03 -8.796157e-03 -2.463757e-03  9.112497e-05
## [542,] -0.0987152511  2.575798e-03 -1.994940e-02  8.161193e-03 -1.262046e-02
## [543,] -0.0565374950  1.610918e-02 -1.295072e-02 -2.390649e-02  4.092165e-03
## [544,]  0.0568923371 -7.840121e-02 -1.162042e-02  3.505356e-03 -6.121733e-03
## [545,] -0.0542291424 -8.247547e-02 -8.960736e-03  1.302883e-02  4.772981e-03
## [546,] -0.0678745818 -1.961314e-02 -6.487119e-03 -4.750888e-03 -3.114620e-03
## [547,]  0.0125381679  4.498783e-02  5.470187e-03 -7.783998e-03 -4.507372e-03
## [548,]  0.0313546289 -4.161718e-02 -2.705643e-03  9.706143e-03  3.657914e-03
## [549,]  0.1006525985  5.511332e-02 -8.274135e-04 -2.590615e-02  8.789459e-04
## [550,] -0.0007909619  3.418774e-02  6.937288e-05 -2.145122e-02 -4.134624e-03
## [551,] -0.0163685109 -1.107701e-02  2.770954e-02  1.795767e-02  8.260042e-03
## [552,] -0.0014215153  5.637368e-02 -3.381745e-03  3.849594e-03 -1.779362e-03
## [553,] -0.1022492547 -9.323360e-03  5.913651e-04  1.263059e-02 -7.162542e-03
## [554,]  0.0044220903  4.297202e-03 -9.650436e-03 -1.615592e-02 -1.435061e-03
## [555,]  0.0024994349 -7.130661e-02  4.473723e-02  1.560585e-02  1.385123e-03
## [556,]  0.0938320141  3.896512e-02 -1.164274e-02 -1.431460e-03  6.878081e-03
## [557,]  0.0152530115 -3.226473e-03  2.268760e-03 -1.799952e-02 -4.947889e-05
## [558,]  0.1510723322  1.702667e-01  3.413466e-02  3.102528e-02  8.728220e-03
## [559,]  0.0407493494  3.978350e-02 -1.130892e-02  4.068695e-03 -6.920526e-03
## [560,]  0.0599659983 -3.787753e-02  2.037519e-02 -3.413149e-04  1.269775e-02
## [561,]  0.0968312180 -1.392626e-02  2.900866e-02  1.731854e-03  4.328273e-03
## [562,]  0.0041827618  2.209661e-02  7.486086e-03 -3.107530e-04  5.831723e-03
## [563,]  0.2037854413 -1.474368e-01 -1.245986e-01  9.015380e-03 -7.118296e-03
## [564,] -0.0729289516  1.450989e-01 -3.945551e-02  7.014761e-02  7.638391e-03
## [565,] -0.1227922446  1.590577e-01  9.843968e-03  7.112909e-03  1.413613e-03
## [566,]  0.0658312978 -6.845211e-02 -2.355466e-02 -2.746212e-02  1.041027e-02
## [567,]  0.0070890278 -2.367063e-02 -2.575490e-03  6.700316e-03 -3.767102e-03
## [568,] -0.1980178555 -2.738532e-02 -6.802653e-02 -8.408929e-02  2.376191e-02
## [569,]  0.3468098821  1.272691e-01 -9.507513e-03 -6.085956e-02  1.945846e-02

We can find the cumulative value for each Principle Componenet

pve = 100 * (pr.out$sdev^2) / sum(pr.out$sdev^2)
par(mfrow=c(1,2))
plot(pve,
     xlab = "Principal Component",
     ylab = "PVE",
     type = "o", col = "blue")

plot(cumsum(pve),
     xlab = "Principal Component",
     ylab = "Cumulative PVE",
     type = "o", col = "red")

Based on the data, the cumulative value of pve in the 11th data does not have a significant increase, therefore we can take up to the 10th pc data.

x <- pr.out$x
new_features <- data.frame(pr.out$x)
new_features <- new_features[1:10]

PCA_bcw_df <- new_features
PCA_bcw_df$diagnosis <- bcw_df$diagnosis

Divide into train and test

set.seed(2021)
m = nrow(bcw_df)
train_ind_PCA <- sample(m, 0.7 * m)
train_df_PCA <- bcw_df[train_ind_PCA, ]
test_df_PCA <- bcw_df[-train_ind_PCA, ]

train_ind_PCA
##   [1] 166 430 442  70 192 325 495 103 361 535 332 146 123 188 387 360 538 164
##  [19] 101 342 354 403 373  73 191 294 274 566 550  79 150 400 335 529 357 148
##  [37] 452 456 467  67 554 121 511 369 155 504 395 526 126 463 482 362 510 300
##  [55] 120  27 568 149 371  89  95 173  75 393  23 235 470 420  94 302 432 263
##  [73] 285 385 147 365 113 502 382 201 115 493 329 138 515 321 557 293 427 413
##  [91] 336 197 187 563 559  58 157   7 320 172  57 247 139 530 500  20 151  45
## [109]   1 143 547 215 525 109 484 527 388 449  13 198 501  85 465  39 384 141
## [127] 165 112 531 214 158 392 178 548  71 257 344 130  53 341 213  43 421 125
## [145]  77 374  69  48 397 203 184 497 227 211 185 564 275 528 491 278 270 159
## [163] 108 410 480 481  93 415 154 295 542  68 167 412 569  37  41 339  49 450
## [181] 229 179 396 250  84 168 391 280 299 152 419 406 545 233  38 520 441 455
## [199] 565 524 469  24 200 503 479 240  28  50 327  31 351 210  29  15 337 220
## [217] 567  90 483 328 182 234 286  60   9 490 422 394 144 439  61  44 262 457
## [235] 256 254 544 377 317  98 309 133 208  97  66 379 417 296  96 319 276 246
## [253] 209 177 269  34 546  87 562 279   8 468 405 245 142 316 243  54 352  92
## [271] 346 330 364 175 399 322 350 129 196 199 517 498 282 225 366  76 137 287
## [289] 242 174 153 435 334 106 217  52 407  11 533 518 428 259  17 297 267 390
## [307] 323 301 464  35 216 118 436  65 207 443 496  56 347 555 438 437 171 205
## [325] 265 560 348 232 539 429 345 472 313 212 272 338  42 506 307 507 553 132
## [343] 226  81 134  25 355 401 416 358   3 190 253 236 249 104 119 514 476 367
## [361] 461 271  80 425  82 556 105 381 110 218 289 116 170  22 494 492 460 363
## [379] 124 127 283 156   6 264  14  10 440 478 424 349 477 445 258 534 224 304
## [397] 448 486

3.5 Training and Test Division

Use set.seed() for reproducible result. Ratio train:test = 70:30.

set.seed(2021)
m = nrow(bcw_df)
train_ind <- sample(m, 0.7 * m)
train_df <- bcw_df2[train_ind, ]
test_df <- bcw_df2[-train_ind, ]

Divide train and test data into PCA

PCA_train_df <- PCA_bcw_df[train_ind, ]
PCA_test_df <- PCA_bcw_df[-train_ind, ]

4. Modelling

we use 4 Machine Learning algorithms.

4.1 Modelling without PCA

4.1.1 Logistic Regression

fit.logit <- glm(diagnosis~. ,
                 data = train_df,
                 family = binomial)
## Warning: glm.fit: fitted probabilities numerically 0 or 1 occurred
summary(fit.logit)
## 
## Call:
## glm(formula = diagnosis ~ ., family = binomial, data = train_df)
## 
## Deviance Residuals: 
##      Min        1Q    Median        3Q       Max  
## -2.29130  -0.06276  -0.01079   0.00266   2.41194  
## 
## Coefficients:
##                         Estimate Std. Error z value Pr(>|z|)    
## (Intercept)             -38.2941    10.8434  -3.532 0.000413 ***
## radius_mean               0.9770     0.3246   3.009 0.002618 ** 
## texture_mean              0.5801     0.1110   5.226 1.73e-07 ***
## smoothness_mean          -0.2969    51.6663  -0.006 0.995414    
## concave.points_mean     134.7234    38.6187   3.489 0.000486 ***
## symmetry_mean            42.5947    20.3845   2.090 0.036657 *  
## fractal_dimension_mean   22.7464   105.3806   0.216 0.829105    
## radius_se                 5.0455     2.9014   1.739 0.082037 .  
## texture_se               -1.5634     0.9470  -1.651 0.098737 .  
## smoothness_se            72.5956   159.1434   0.456 0.648272    
## concave.points_se      -160.9316   122.3363  -1.315 0.188347    
## symmetry_se             -27.4352    60.9517  -0.450 0.652628    
## fractal_dimension_se   -351.4736   288.8728  -1.217 0.223716    
## ---
## Signif. codes:  0 '***' 0.001 '**' 0.01 '*' 0.05 '.' 0.1 ' ' 1
## 
## (Dispersion parameter for binomial family taken to be 1)
## 
##     Null deviance: 516.229  on 397  degrees of freedom
## Residual deviance:  75.269  on 385  degrees of freedom
## AIC: 101.27
## 
## Number of Fisher Scoring iterations: 9

4.1.2 Decision Tree

library(party)
## Loading required package: grid
## Loading required package: mvtnorm
## Loading required package: modeltools
## Loading required package: stats4
## Loading required package: strucchange
## Loading required package: zoo
## 
## Attaching package: 'zoo'
## The following objects are masked from 'package:base':
## 
##     as.Date, as.Date.numeric
## Loading required package: sandwich
fit.ctree <- ctree(diagnosis~. , data = train_df)
plot(fit.ctree, main = "Conditional Inference Tree")

4.1.3 Random Forest

library(randomForest)
## randomForest 4.6-14
## Type rfNews() to see new features/changes/bug fixes.
## 
## Attaching package: 'randomForest'
## The following object is masked from 'package:gridExtra':
## 
##     combine
## The following object is masked from 'package:ggplot2':
## 
##     margin
set.seed(2021)
fit.forest <- randomForest(formula = diagnosis ~ ., data = train_df,
                           na.action = na.roughfix,
                           importance = TRUE)
fit.forest
## 
## Call:
##  randomForest(formula = diagnosis ~ ., data = train_df, importance = TRUE,      na.action = na.roughfix) 
##                Type of random forest: classification
##                      Number of trees: 500
## No. of variables tried at each split: 3
## 
##         OOB estimate of  error rate: 5.28%
## Confusion matrix:
##     B   M class.error
## B 249   9  0.03488372
## M  12 128  0.08571429

4.1.4 Support Vector Machine (SVM)

library(e1071)
set.seed(2021)
fit.svm <- svm(diagnosis~., data=train_df)
fit.svm
## 
## Call:
## svm(formula = diagnosis ~ ., data = train_df)
## 
## 
## Parameters:
##    SVM-Type:  C-classification 
##  SVM-Kernel:  radial 
##        cost:  1 
## 
## Number of Support Vectors:  119

4.2 Modelling with PCA

4.2.1 Logistic Regression

PCA_fit.logit <- glm(diagnosis~., 
                 data = PCA_train_df, 
                 family = binomial)
## Warning: glm.fit: fitted probabilities numerically 0 or 1 occurred
summary(PCA_fit.logit)
## 
## Call:
## glm(formula = diagnosis ~ ., family = binomial, data = PCA_train_df)
## 
## Deviance Residuals: 
##      Min        1Q    Median        3Q       Max  
## -2.12796  -0.00016   0.00000   0.00000   2.01785  
## 
## Coefficients:
##             Estimate Std. Error z value Pr(>|z|)   
## (Intercept) -3.12682    1.69063  -1.849  0.06439 . 
## PC1         -7.94011    2.97481  -2.669  0.00761 **
## PC2          4.99803    1.99155   2.510  0.01209 * 
## PC3         -2.71777    1.22352  -2.221  0.02633 * 
## PC4         -2.67321    1.20002  -2.228  0.02590 * 
## PC5          2.76192    1.09697   2.518  0.01181 * 
## PC6          0.05238    0.42531   0.123  0.90198   
## PC7         -2.32447    1.68517  -1.379  0.16778   
## PC8         -2.45275    1.34029  -1.830  0.06725 . 
## PC9          5.66907    2.52441   2.246  0.02472 * 
## PC10         0.34542    1.45719   0.237  0.81262   
## ---
## Signif. codes:  0 '***' 0.001 '**' 0.01 '*' 0.05 '.' 0.1 ' ' 1
## 
## (Dispersion parameter for binomial family taken to be 1)
## 
##     Null deviance: 516.229  on 397  degrees of freedom
## Residual deviance:  20.676  on 387  degrees of freedom
## AIC: 42.676
## 
## Number of Fisher Scoring iterations: 12

4.2.2 Decision Tree

library(party)
PCA_fit.ctree <- ctree(diagnosis~. , data = PCA_train_df)
plot(PCA_fit.ctree, main = "Conditional Inference Tree (PCA)")

4.2.3 Random FOrest

set.seed(2021)
PCA_fit.forest <- randomForest(formula = diagnosis ~ ., data = PCA_train_df,
                           na.action = na.roughfix,
                           importance = TRUE)
PCA_fit.forest
## 
## Call:
##  randomForest(formula = diagnosis ~ ., data = PCA_train_df, importance = TRUE,      na.action = na.roughfix) 
##                Type of random forest: classification
##                      Number of trees: 500
## No. of variables tried at each split: 3
## 
##         OOB estimate of  error rate: 5.53%
## Confusion matrix:
##     B   M class.error
## B 246  12  0.04651163
## M  10 130  0.07142857

4.2.4 Support Vector Machine

set.seed(2021)
PCA_fit.svm <- svm(diagnosis~., data=PCA_train_df)
PCA_fit.svm
## 
## Call:
## svm(formula = diagnosis ~ ., data = PCA_train_df)
## 
## 
## Parameters:
##    SVM-Type:  C-classification 
##  SVM-Kernel:  radial 
##        cost:  1 
## 
## Number of Support Vectors:  147

5. Evaluation

5.1 Evaluation without PCA

We compute accuracy, precision, recall, and F1 score.

performance <- function(table, n=2){
  tp = table[2,2]
  tn = table[1,1]
  fp = table[1,2]
  fn = table[2,1]
  
  sensitivity = tp/(tp+fn) # recall
  specificity = tn/(tn+fp)
  ppp = tp/(tp+fp) # precision
  npp = tn/(tn+fn)
  hitrate = (tp+tn)/(tp+tn+fp+fn) # accuracy
  
  result <- paste("Sensitivity = ", round(sensitivity, n),
                  "\nSpecificity = ", round(specificity, n),
                  "\nPositive Predictive Value = ", round(ppp,n), "\nNegative Predictive Value = ",round(npp, n),
                  "nAccuracy = ", round(hitrate, n))
  cat(result)
}
prob <- predict(fit.logit, test_df, type = "response")
logit.pred <- factor(prob > 0.5, levels = c(FALSE, TRUE),
                     labels = c("benign", "malignant"))

logit.perf <- table(test_df$diagnosis, logit.pred,
                    dnn = c("Actual", "predicted"))
logit.perf
##       predicted
## Actual benign malignant
##      B     95         4
##      M      7        65
performance(logit.perf)
## Sensitivity =  0.9 
## Specificity =  0.96 
## Positive Predictive Value =  0.94 
## Negative Predictive Value =  0.93 nAccuracy =  0.94
fit.ctree <- ctree(formula = diagnosis ~ . , data = train_df)

ctree.pred <- predict(fit.ctree, test_df, type = "response")
ctree.perf <- table(test_df$diagnosis, ctree.pred,
                    dnn = c("Actual", "predicted"))

ctree.perf
##       predicted
## Actual  B  M
##      B 92  7
##      M  7 65
performance(ctree.perf)
## Sensitivity =  0.9 
## Specificity =  0.93 
## Positive Predictive Value =  0.9 
## Negative Predictive Value =  0.93 nAccuracy =  0.92
forest.pred <- predict(fit.forest, test_df, type = "response")
forest.perf <- table(test_df$diagnosis, forest.pred,
                    dnn=c("Actual","Predicted"))
forest.perf
##       Predicted
## Actual  B  M
##      B 97  2
##      M  7 65
performance (forest.perf)
## Sensitivity =  0.9 
## Specificity =  0.98 
## Positive Predictive Value =  0.97 
## Negative Predictive Value =  0.93 nAccuracy =  0.95
svm.pred <- predict(fit.svm, test_df, type = "response")
svm.perf <- table(test_df$diagnosis, svm.pred,
                  dnn = c("Actual", "Predicted"))
svm.perf
##       Predicted
## Actual  B  M
##      B 96  3
##      M  8 64
performance(svm.perf)
## Sensitivity =  0.89 
## Specificity =  0.97 
## Positive Predictive Value =  0.96 
## Negative Predictive Value =  0.92 nAccuracy =  0.94

5.2 Evaluation with PCA

We compute accuracy, precision, recall, and F1 score.

PCA_prob <- predict(PCA_fit.logit, PCA_test_df, type = "response")
PCA_logit.pred <- factor(PCA_prob > 0.5, levels = c(FALSE, TRUE),
                     labels = c("benign", "malignant"))

PCA_logit.perf <- table(PCA_test_df$diagnosis, PCA_logit.pred,
                    dnn = c("Actual", "predicted"))
PCA_logit.perf
##       predicted
## Actual benign malignant
##      B     96         3
##      M      4        68
performance(PCA_logit.perf)
## Sensitivity =  0.94 
## Specificity =  0.97 
## Positive Predictive Value =  0.96 
## Negative Predictive Value =  0.96 nAccuracy =  0.96
PCA_fit.ctree <- ctree(formula = diagnosis ~ . , data = PCA_train_df)

PCA_ctree.pred <- predict(PCA_fit.ctree, PCA_test_df, type = "response")
PCA_ctree.perf <- table(PCA_test_df$diagnosis, PCA_ctree.pred,
                    dnn = c("Actual", "predicted"))

PCA_ctree.perf
##       predicted
## Actual  B  M
##      B 96  3
##      M  6 66
performance(PCA_ctree.perf)
## Sensitivity =  0.92 
## Specificity =  0.97 
## Positive Predictive Value =  0.96 
## Negative Predictive Value =  0.94 nAccuracy =  0.95
PCA_forest.pred <- predict(PCA_fit.forest, PCA_test_df, type = "response")
PCA_forest.perf <- table(PCA_test_df$diagnosis, PCA_forest.pred,
                    dnn=c("Actual","Predicted"))
PCA_forest.perf
##       Predicted
## Actual  B  M
##      B 99  0
##      M  5 67
performance (PCA_forest.perf)
## Sensitivity =  0.93 
## Specificity =  1 
## Positive Predictive Value =  1 
## Negative Predictive Value =  0.95 nAccuracy =  0.97
PCA_svm.pred <- predict(PCA_fit.svm, PCA_test_df, type = "response")
PCA_svm.perf <- table(PCA_test_df$diagnosis, PCA_svm.pred,
                  dnn = c("Actual", "Predicted"))
PCA_svm.perf
##       Predicted
## Actual  B  M
##      B 94  5
##      M  7 65
performance(PCA_svm.perf)
## Sensitivity =  0.9 
## Specificity =  0.95 
## Positive Predictive Value =  0.93 
## Negative Predictive Value =  0.93 nAccuracy =  0.93

6. Recommendation

  1. Random forest algorithm is the best among all the tested algorithms.
  2. Based on decision tree model, the most important variable are concave.point, radius_mean, and texture_mean.
  3. The result can be improved by better data preparation using other algorithms. However, the current result surpass human level performance (79% accuracy). So, it can be deployed as second opinion for the doctor.