FOT Children Born Preterm - Buenos Aires, Argentina

Healthy Controls x VLBW

Demographics Controls x VLBW

##                     Stratified by group2
##                      Controls                VLBW                    p      test   
##   n                      24                      36                                
##   sex = Male (%)         11 (45.8)               20 (55.6)            0.635        
##   age (median [IQR])   5.56 [4.78, 6.09]       5.09 [4.54, 5.46]      0.103 nonnorm
##   h (median [IQR])   115.50 [110.00, 120.50] 107.00 [103.50, 109.50] <0.001 nonnorm
##   wt (median [IQR])   21.50 [19.00, 25.50]    16.40 [14.80, 18.40]   <0.001 nonnorm

Oscillometry Controls x VLBW

##                            Stratified by group2
##                             Controls             VLBW                 p      test   
##   n                            24                   36                              
##   reprebd_6 (median [IQR])   8.64 [7.22, 9.33]    9.71 [8.55, 11.23]   0.015 nonnorm
##   reprebd_8 (median [IQR])   8.12 [7.27, 8.81]    8.93 [8.15, 10.30]   0.046 nonnorm
##   reprebd_10 (median [IQR])  7.68 [6.86, 8.50]    8.81 [7.76, 10.20]   0.030 nonnorm
##   imprebd_6 (median [IQR])  -2.52 [-3.09, -1.94] -3.54 [-4.59, -2.42]  0.013 nonnorm
##   imprebd_8 (median [IQR])  -1.93 [-2.63, -1.70] -2.88 [-3.97, -1.90]  0.048 nonnorm
##   imprebd_10 (median [IQR]) -1.58 [-2.34, -1.20] -2.54 [-3.50, -1.25]  0.050 nonnorm

##                            Stratified by group2
##                             Controls             VLBW                 p      test   
##   n                            24                   36                              
##   prebd_r (median [IQR])     7.13 [6.26, 7.70]    8.32 [6.69, 8.91]    0.046 nonnorm
##   prebd_c (median [IQR])     0.01 [0.01, 0.01]    0.01 [0.00, 0.01]    0.333 nonnorm
##   prebd_l (median [IQR])     0.01 [0.00, 0.01]    0.00 [0.00, 0.00]    0.003 nonnorm
##   prebd_fres (median [IQR]) 20.31 [19.31, 25.27] 22.47 [17.45, 26.54]  0.739 nonnorm

##                                  Stratified by group2
##                                   Controls             VLBW                 p      test   
##   n                                  24                   36                              
##   prebd_med_ree (median [IQR])     6.88 [6.42, 8.68]    8.62 [7.45, 9.94]    0.020 nonnorm
##   prebd_med_rei (median [IQR])     6.40 [5.26, 7.01]    7.52 [6.30, 9.20]    0.015 nonnorm
##   prebd_med_reerei (median [IQR])  0.57 [0.16, 1.39]    0.83 [0.09, 1.44]    0.985 nonnorm
##   prebd_med_xee (median [IQR])    -0.81 [-1.66, -0.29] -2.26 [-3.21, -1.31]  0.001 nonnorm
##   prebd_med_xei (median [IQR])    -1.12 [-2.03, -0.59] -2.16 [-2.90, -1.31]  0.011 nonnorm
##   prebd_med_xeexei (median [IQR])  0.38 [-0.13, 0.76]   0.13 [-0.09, 0.48]   0.212 nonnorm

Figures

Spectral Oscillometry

Intra-breath Oscillometry

Analysis in VLBW

Oscillometry in VLBW by birth weight

##                            Stratified by bw.f
##                             BW < 1000g           BW > 1000g           p      test   
##   n                            18                   18                              
##   reprebd_6 (median [IQR])   9.71 [9.08, 12.94]   9.53 [8.39, 10.62]   0.335 nonnorm
##   reprebd_8 (median [IQR])   9.27 [8.42, 12.22]   8.79 [7.79, 9.86]    0.357 nonnorm
##   reprebd_10 (median [IQR])  8.89 [8.06, 11.33]   8.30 [7.42, 9.44]    0.236 nonnorm
##   imprebd_6 (median [IQR])  -3.54 [-5.12, -2.42] -3.58 [-4.05, -2.42]  0.726 nonnorm
##   imprebd_8 (median [IQR])  -3.18 [-4.76, -2.13] -2.35 [-3.73, -1.84]  0.335 nonnorm
##   imprebd_10 (median [IQR]) -2.73 [-4.34, -1.90] -2.27 [-3.01, -1.24]  0.313 nonnorm

##                            Stratified by bw.f
##                             BW < 1000g           BW > 1000g           p      test   
##   n                            18                   18                              
##   prebd_r (median [IQR])     8.56 [7.12, 9.36]    7.94 [6.69, 8.59]    0.219 nonnorm
##   prebd_c (median [IQR])     0.01 [0.00, 0.01]    0.01 [0.01, 0.01]    0.539 nonnorm
##   prebd_l (median [IQR])     0.00 [0.00, 0.01]    0.00 [0.00, 0.00]    0.456 nonnorm
##   prebd_fres (median [IQR]) 16.31 [13.84, 20.37] 26.56 [23.30, 29.56]  0.083 nonnorm

##                                  Stratified by bw.f
##                                   BW < 1000g           BW > 1000g           p      test   
##   n                                  18                   18                              
##   prebd_med_ree (median [IQR])     9.21 [8.13, 10.87]   8.27 [7.00, 9.61]    0.345 nonnorm
##   prebd_med_rei (median [IQR])     8.44 [7.05, 10.05]   6.68 [6.14, 8.84]    0.160 nonnorm
##   prebd_med_reerei (median [IQR])  0.63 [-0.07, 1.03]   1.34 [0.21, 1.55]    0.300 nonnorm
##   prebd_med_xee (median [IQR])    -2.84 [-3.45, -2.01] -1.56 [-2.45, -1.23]  0.160 nonnorm
##   prebd_med_xei (median [IQR])    -2.68 [-3.61, -1.02] -1.93 [-2.46, -1.40]  0.279 nonnorm
##   prebd_med_xeexei (median [IQR])  0.12 [-0.19, 0.38]   0.14 [-0.05, 0.56]   0.596 nonnorm

Oscillometry in VLBW by gestational age

##                            Stratified by gest
##                             GA<28w               GA>28w               p      test   
##   n                            17                   19                              
##   reprebd_6 (median [IQR])  10.01 [8.50, 11.14]   9.55 [8.55, 11.23]   0.690 nonnorm
##   reprebd_8 (median [IQR])   9.09 [8.27, 10.86]   8.89 [8.15, 10.22]   0.507 nonnorm
##   reprebd_10 (median [IQR])  8.52 [7.68, 9.90]    8.81 [7.97, 10.20]   0.859 nonnorm
##   imprebd_6 (median [IQR])  -3.58 [-5.06, -2.28] -3.54 [-4.14, -2.43]  0.894 nonnorm
##   imprebd_8 (median [IQR])  -2.66 [-4.22, -1.99] -2.88 [-3.74, -1.90]  0.859 nonnorm
##   imprebd_10 (median [IQR]) -2.47 [-4.22, -1.28] -2.54 [-3.27, -1.25]  0.757 nonnorm

##                            Stratified by gest
##                             GA<28w               GA>28w               p      test   
##   n                            17                   19                              
##   prebd_r (median [IQR])     7.94 [6.98, 9.19]    8.45 [6.35, 8.60]    0.565 nonnorm
##   prebd_c (median [IQR])     0.01 [0.00, 0.01]    0.01 [0.00, 0.01]    0.723 nonnorm
##   prebd_l (median [IQR])     0.00 [0.00, 0.00]    0.00 [0.00, 0.01]    0.121 nonnorm
##   prebd_fres (median [IQR]) 28.99 [26.56, 30.14] 18.59 [14.04, 20.81]  0.053 nonnorm

##                                  Stratified by gest
##                                   GA<28w               GA>28w               p      test   
##   n                                  17                   19                              
##   prebd_med_ree (median [IQR])     9.52 [7.42, 10.87]   8.27 [7.58, 9.31]    0.384 nonnorm
##   prebd_med_rei (median [IQR])     7.49 [6.34, 9.77]    7.54 [6.11, 9.03]    0.869 nonnorm
##   prebd_med_reerei (median [IQR])  1.34 [0.66, 1.55]    0.37 [-0.07, 1.41]   0.230 nonnorm
##   prebd_med_xee (median [IQR])    -2.45 [-3.32, -1.82] -1.72 [-2.94, -1.01]  0.335 nonnorm
##   prebd_med_xei (median [IQR])    -2.65 [-3.36, -2.01] -1.70 [-2.58, -1.15]  0.269 nonnorm
##   prebd_med_xeexei (median [IQR])  0.14 [-0.13, 0.31]   0.12 [-0.02, 0.50]   0.589 nonnorm

Oscillometry in VLBW by cluster

##                            Stratified by cluster
##                             1                    2                    3                    p      test   
##   n                            12                   18                    6                              
##   reprebd_6 (median [IQR])   9.15 [8.18, 10.20]   9.92 [8.92, 11.25]  10.54 [9.54, 12.84]   0.410 nonnorm
##   reprebd_8 (median [IQR])   8.49 [7.49, 9.49]    9.27 [8.61, 10.34]   8.93 [8.37, 11.01]   0.355 nonnorm
##   reprebd_10 (median [IQR])  8.06 [7.17, 9.41]    9.18 [8.30, 10.27]   8.05 [7.74, 10.28]   0.411 nonnorm
##   imprebd_6 (median [IQR])  -2.59 [-3.87, -2.32] -3.66 [-4.36, -2.38] -6.53 [-7.12, -5.01]  0.214 nonnorm
##   imprebd_8 (median [IQR])  -2.33 [-3.44, -1.39] -2.95 [-3.91, -2.12] -5.31 [-6.16, -3.84]  0.186 nonnorm
##   imprebd_10 (median [IQR]) -2.25 [-3.16, -1.15] -2.66 [-3.21, -1.43] -4.79 [-5.86, -3.54]  0.235 nonnorm

##                            Stratified by cluster
##                             1                    2                    3                    p      test   
##   n                            12                   18                    6                              
##   prebd_r (median [IQR])     7.30 [6.45, 8.45]    8.56 [7.96, 8.92]    7.07 [6.74, 8.72]    0.226 nonnorm
##   prebd_c (median [IQR])     0.01 [0.01, 0.01]    0.01 [0.01, 0.01]    0.00 [0.00, 0.01]    0.151 nonnorm
##   prebd_l (median [IQR])     0.00 [0.00, 0.01]    0.00 [0.00, 0.00]    0.00 [0.00, 0.00]    0.037 nonnorm
##   prebd_fres (median [IQR]) 24.13 [20.81, 25.72] 13.63 [13.43, 13.84] 31.29 [31.29, 31.29]  0.072 nonnorm

##                                  Stratified by cluster
##                                   1                    2                    3                    p      test   
##   n                                  12                   18                    6                              
##   prebd_med_ree (median [IQR])     7.99 [7.10, 8.67]    9.31 [8.29, 9.98]    7.06 [6.72, 8.97]    0.370 nonnorm
##   prebd_med_rei (median [IQR])     6.68 [5.61, 8.11]    8.55 [7.12, 9.77]    6.36 [6.31, 8.30]    0.166 nonnorm
##   prebd_med_reerei (median [IQR])  1.04 [0.46, 1.48]    0.89 [-0.10, 1.56]   0.63 [0.37, 0.66]    0.655 nonnorm
##   prebd_med_xee (median [IQR])    -1.85 [-2.55, -1.10] -2.45 [-3.38, -1.32] -2.31 [-2.82, -1.88]  0.689 nonnorm
##   prebd_med_xei (median [IQR])    -1.69 [-2.57, -0.97] -2.39 [-3.02, -1.51] -2.24 [-2.93, -2.16]  0.608 nonnorm
##   prebd_med_xeexei (median [IQR])  0.06 [-0.12, 0.15]   0.18 [-0.13, 0.52]   0.28 [0.10, 0.46]    0.758 nonnorm

Oscillometry in VLBW by wheezing_12m

##                            Stratified by wheezing_12m
##                             0                    1                    p      test   
##   n                            23                   10                              
##   reprebd_6 (median [IQR])   9.90 [8.77, 11.23]   9.02 [8.01, 11.11]   0.591 nonnorm
##   reprebd_8 (median [IQR])   9.12 [8.49, 10.22]   8.35 [7.39, 11.05]   0.696 nonnorm
##   reprebd_10 (median [IQR])  8.89 [8.05, 10.20]   8.12 [6.84, 10.00]   0.526 nonnorm
##   imprebd_6 (median [IQR])  -3.54 [-4.59, -2.42] -3.58 [-4.62, -2.49]  0.922 nonnorm
##   imprebd_8 (median [IQR])  -2.88 [-3.97, -1.90] -2.66 [-4.04, -1.90]  0.961 nonnorm
##   imprebd_10 (median [IQR]) -2.54 [-3.50, -1.25] -2.47 [-3.90, -1.62]  0.922 nonnorm

##                            Stratified by wheezing_12m
##                             0                    1                    p      test   
##   n                            23                   10                              
##   prebd_r (median [IQR])     8.32 [7.12, 8.62]    7.81 [6.09, 9.27]    0.845 nonnorm
##   prebd_c (median [IQR])     0.01 [0.00, 0.01]    0.01 [0.00, 0.01]    1.000 nonnorm
##   prebd_l (median [IQR])     0.00 [0.00, 0.00]    0.00 [0.00, 0.01]    0.733 nonnorm
##   prebd_fres (median [IQR]) 24.92 [22.74, 26.54] 17.43 [13.84, 23.43]  0.386 nonnorm

##                                  Stratified by wheezing_12m
##                                   0                    1                    p      test   
##   n                                  23                   10                              
##   prebd_med_ree (median [IQR])     8.95 [8.05, 9.94]    7.42 [6.39, 9.98]    0.242 nonnorm
##   prebd_med_rei (median [IQR])     7.52 [6.59, 8.75]    7.94 [5.99, 10.03]   1.000 nonnorm
##   prebd_med_reerei (median [IQR])  1.18 [0.35, 1.61]    0.28 [-0.19, 0.79]   0.047 nonnorm
##   prebd_med_xee (median [IQR])    -2.38 [-3.21, -1.47] -1.73 [-2.77, -0.93]  0.360 nonnorm
##   prebd_med_xei (median [IQR])    -2.13 [-2.90, -1.31] -2.33 [-2.91, -1.71]  0.799 nonnorm
##   prebd_med_xeexei (median [IQR])  0.06 [-0.25, 0.36]   0.42 [0.05, 0.64]    0.084 nonnorm

Oscillometry in VLBW by wheezing_3y

##                            Stratified by wheezing_3y
##                             0                    1                    p      test   
##   n                             7                   22                              
##   reprebd_6 (median [IQR])  10.49 [9.81, 11.38]   9.69 [8.51, 11.24]   0.394 nonnorm
##   reprebd_8 (median [IQR])   9.75 [8.66, 10.54]   8.91 [8.06, 10.24]   0.429 nonnorm
##   reprebd_10 (median [IQR])  9.34 [8.34, 10.73]   8.64 [7.84, 10.23]   0.465 nonnorm
##   imprebd_6 (median [IQR])  -3.82 [-4.83, -2.74] -3.61 [-4.71, -2.46]  0.951 nonnorm
##   imprebd_8 (median [IQR])  -3.05 [-4.36, -2.36] -2.62 [-3.98, -1.80]  0.715 nonnorm
##   imprebd_10 (median [IQR]) -2.85 [-4.02, -1.87] -2.41 [-3.63, -1.21]  0.626 nonnorm

##                            Stratified by wheezing_3y
##                             0                    1                    p      test   
##   n                             7                   22                              
##   prebd_r (median [IQR])     8.68 [7.11, 9.24]    8.31 [6.91, 8.70]    0.503 nonnorm
##   prebd_c (median [IQR])     0.01 [0.00, 0.01]    0.01 [0.00, 0.01]    0.855 nonnorm
##   prebd_l (median [IQR])     0.00 [0.00, 0.01]    0.00 [0.00, 0.00]    0.626 nonnorm
##   prebd_fres (median [IQR]) 24.92 [24.53, 25.32] 18.59 [14.04, 20.81]  0.245 nonnorm

##                                  Stratified by wheezing_3y
##                                   0                    1                    p      test   
##   n                                   7                   22                              
##   prebd_med_ree (median [IQR])     8.31 [7.80, 9.03]    8.44 [7.00, 9.98]    0.750 nonnorm
##   prebd_med_rei (median [IQR])     8.77 [7.40, 9.42]    7.14 [6.19, 9.54]    0.750 nonnorm
##   prebd_med_reerei (median [IQR])  0.57 [0.10, 1.20]    0.89 [0.21, 1.47]    0.373 nonnorm
##   prebd_med_xee (median [IQR])    -2.08 [-2.99, -1.24] -2.01 [-3.12, -1.20]  1.000 nonnorm
##   prebd_med_xei (median [IQR])    -2.21 [-3.35, -1.96] -2.24 [-3.02, -1.40]  0.799 nonnorm
##   prebd_med_xeexei (median [IQR])  0.32 [-0.01, 0.63]   0.15 [-0.01, 0.43]   0.567 nonnorm

Oscillometry in VLBW by wheezing_after_3y

##                            Stratified by wheezing_after_3y
##                             0                    1                    p      test   
##   n                            15                   14                              
##   reprebd_6 (median [IQR])   9.53 [8.60, 11.17]   9.80 [8.01, 11.88]   0.918 nonnorm
##   reprebd_8 (median [IQR])   8.89 [8.44, 10.16]   8.91 [7.39, 10.83]   0.797 nonnorm
##   reprebd_10 (median [IQR])  8.93 [8.01, 10.13]   8.43 [6.84, 10.62]   0.572 nonnorm
##   imprebd_6 (median [IQR])  -2.53 [-3.92, -2.32] -3.84 [-6.47, -2.49]  0.328 nonnorm
##   imprebd_8 (median [IQR])  -2.15 [-3.09, -1.72] -3.34 [-5.06, -1.90]  0.258 nonnorm
##   imprebd_10 (median [IQR]) -1.78 [-2.83, -1.22] -2.96 [-5.05, -1.62]  0.328 nonnorm

##                            Stratified by wheezing_after_3y
##                             0                    1                    p      test   
##   n                            15                   14                              
##   prebd_r (median [IQR])     8.31 [7.37, 9.01]    7.81 [6.09, 8.91]    0.411 nonnorm
##   prebd_c (median [IQR])     0.01 [0.01, 0.01]    0.01 [0.00, 0.01]    0.328 nonnorm
##   prebd_l (median [IQR])     0.00 [0.00, 0.00]    0.00 [0.00, 0.01]    0.877 nonnorm
##   prebd_fres (median [IQR]) 24.13 [21.36, 26.56] 17.43 [13.84, 23.43]  0.480 nonnorm

##                                  Stratified by wheezing_after_3y
##                                   0                    1                    p      test   
##   n                                  15                   14                              
##   prebd_med_ree (median [IQR])     9.11 [8.27, 10.07]   7.42 [6.49, 9.98]    0.231 nonnorm
##   prebd_med_rei (median [IQR])     8.44 [6.68, 9.03]    6.95 [5.99, 10.03]   0.744 nonnorm
##   prebd_med_reerei (median [IQR])  1.34 [0.36, 1.57]    0.50 [-0.08, 1.13]   0.142 nonnorm
##   prebd_med_xee (median [IQR])    -1.72 [-2.84, -1.38] -2.16 [-3.03, -1.06]  0.957 nonnorm
##   prebd_med_xei (median [IQR])    -2.02 [-2.65, -1.36] -2.16 [-2.91, -1.56]  0.586 nonnorm
##   prebd_med_xeexei (median [IQR])  0.01 [-0.19, 0.18]   0.21 [-0.02, 0.58]   0.253 nonnorm

Oscillometry in VLBW by hosp_3y

##                            Stratified by hosp_3y
##                             0                    1                    p      test   
##   n                            21                   12                              
##   reprebd_6 (median [IQR])   9.71 [8.48, 11.05]   9.69 [8.68, 13.08]   0.680 nonnorm
##   reprebd_8 (median [IQR])   9.12 [7.95, 10.26]   8.91 [8.48, 11.84]   0.551 nonnorm
##   reprebd_10 (median [IQR])  8.89 [7.68, 9.85]    8.48 [7.83, 10.84]   0.854 nonnorm
##   imprebd_6 (median [IQR])  -3.54 [-4.10, -2.42] -3.61 [-6.51, -2.43]  0.551 nonnorm
##   imprebd_8 (median [IQR])  -2.95 [-3.80, -1.59] -2.35 [-5.22, -2.14]  0.409 nonnorm
##   imprebd_10 (median [IQR]) -2.66 [-3.16, -1.22] -2.41 [-5.56, -1.92]  0.409 nonnorm

##                            Stratified by hosp_3y
##                             0                    1                    p      test   
##   n                            21                   12                              
##   prebd_r (median [IQR])     8.32 [6.68, 8.76]    8.08 [7.08, 9.01]    0.748 nonnorm
##   prebd_c (median [IQR])     0.01 [0.01, 0.01]    0.01 [0.00, 0.01]    0.463 nonnorm
##   prebd_l (median [IQR])     0.00 [0.00, 0.01]    0.00 [0.00, 0.00]    0.251 nonnorm
##   prebd_fres (median [IQR]) 20.81 [16.31, 24.92] 31.29 [31.29, 31.29]  0.127 nonnorm

##                                  Stratified by hosp_3y
##                                   0                    1                    p      test   
##   n                                  21                   12                              
##   prebd_med_ree (median [IQR])     8.30 [7.63, 9.47]    9.44 [7.36, 10.63]   0.338 nonnorm
##   prebd_med_rei (median [IQR])     7.09 [6.16, 8.63]    8.78 [6.64, 10.04]   0.250 nonnorm
##   prebd_med_reerei (median [IQR])  0.96 [0.10, 1.53]    0.66 [0.16, 1.38]    0.565 nonnorm
##   prebd_med_xee (median [IQR])    -1.96 [-2.85, -0.99] -2.58 [-3.32, -1.63]  0.250 nonnorm
##   prebd_med_xei (median [IQR])    -1.64 [-2.54, -0.93] -2.66 [-3.58, -2.31]  0.024 nonnorm
##   prebd_med_xeexei (median [IQR])  0.09 [-0.32, 0.45]   0.16 [-0.07, 0.55]   0.533 nonnorm

Oscillometry in VLBW by hosp_after_3y

##                            Stratified by hosp_after_3y
##                             0                    1                    p      test   
##   n                            30                    3                              
##   reprebd_6 (median [IQR])   9.81 [8.60, 11.14]  11.23 [9.89, 12.58]   0.721 nonnorm
##   reprebd_8 (median [IQR])   9.02 [8.44, 10.28]  10.17 [8.98, 11.35]   0.789 nonnorm
##   reprebd_10 (median [IQR])  8.85 [7.99, 10.02]   9.38 [8.41, 10.35]   0.929 nonnorm
##   imprebd_6 (median [IQR])  -3.60 [-4.48, -2.42] -5.86 [-7.04, -4.68]  0.326 nonnorm
##   imprebd_8 (median [IQR])  -2.91 [-3.94, -1.95] -4.75 [-5.93, -3.56]  0.284 nonnorm
##   imprebd_10 (median [IQR]) -2.60 [-3.44, -1.26] -4.35 [-5.38, -3.31]  0.326 nonnorm

##                            Stratified by hosp_after_3y
##                             0                    1                    p      test   
##   n                            30                    3                              
##   prebd_r (median [IQR])     8.38 [6.80, 8.84]    8.11 [7.59, 8.63]    0.858 nonnorm
##   prebd_c (median [IQR])     0.01 [0.00, 0.01]    0.00 [0.00, 0.01]    0.246 nonnorm
##   prebd_l (median [IQR])     0.00 [0.00, 0.01]    0.00 [0.00, 0.00]    0.475 nonnorm
##   prebd_fres (median [IQR]) 20.81 [16.31, 24.92] 31.29 [31.29, 31.29]  0.127 nonnorm

##                                  Stratified by hosp_after_3y
##                                   0                    1                    p      test   
##   n                                  30                    3                              
##   prebd_med_ree (median [IQR])     8.80 [7.79, 9.90]    9.69 [8.38, 11.00]   0.643 nonnorm
##   prebd_med_rei (median [IQR])     7.54 [6.31, 9.09]    9.18 [7.77, 10.60]   0.517 nonnorm
##   prebd_med_reerei (median [IQR])  0.89 [0.01, 1.41]    0.51 [0.41, 0.60]    0.579 nonnorm
##   prebd_med_xee (median [IQR])    -2.31 [-3.17, -1.38] -3.47 [-4.48, -2.45]  0.579 nonnorm
##   prebd_med_xei (median [IQR])    -2.24 [-2.79, -1.36] -3.71 [-4.52, -2.89]  0.308 nonnorm
##   prebd_med_xeexei (median [IQR])  0.12 [-0.07, 0.48]   0.24 [0.04, 0.44]    0.853 nonnorm