EMAlongi_waves
Emily Moraes
9/27/2020
Depression Score by this followup
## Type III Analysis of Variance Table with Satterthwaite's method
## Sum Sq Mean Sq NumDF DenDF F value Pr(>F)
## thisfollowup 94.708 23.677 4 162.7 2.0142 0.09486 .
## ---
## Signif. codes: 0 '***' 0.001 '**' 0.01 '*' 0.05 '.' 0.1 ' ' 1## $`emmeans of thisfollowup`
## thisfollowup emmean SE df lower.CL upper.CL
## 1year 6.00 0.510 249 4.68 7.32
## 2year 6.27 0.859 197 4.04 8.49
## 3year 6.07 1.436 156 2.34 9.81
## 6month 4.46 0.519 250 3.11 5.80
## 9month 6.84 1.104 250 3.99 9.70
##
## Degrees-of-freedom method: kenward-roger
## Confidence level used: 0.95
## Conf-level adjustment: sidak method for 5 estimates
##
## $`pairwise differences of thisfollowup`
## contrast estimate SE df t.ratio p.value
## 1year - 2year -0.2687 0.890 125 -0.302 0.9982
## 1year - 3year -0.0744 1.469 134 -0.051 1.0000
## 1year - 6month 1.5415 0.642 166 2.401 0.1201
## 1year - 9month -0.8478 1.190 244 -0.712 0.9535
## 2year - 3year 0.1943 1.491 105 0.130 0.9999
## 2year - 6month 1.8102 0.982 184 1.844 0.3516
## 2year - 9month -0.5791 1.358 220 -0.426 0.9931
## 3year - 6month 1.6159 1.516 157 1.066 0.8236
## 3year - 9month -0.7734 1.798 189 -0.430 0.9928
## 6month - 9month -2.3893 1.215 249 -1.967 0.2851
##
## Degrees-of-freedom method: kenward-roger
## P value adjustment: tukey method for comparing a family of 5 estimates
N(6month) = 96
N(9month) = 21
N(1year) = 97
N(2year) = 31
N(3year) = 10
N(NA) = 53
N(Total) = 308 / 325
Depression Score by Date
## Type III Analysis of Variance Table with Satterthwaite's method
## Sum Sq Mean Sq NumDF DenDF F value Pr(>F)
## EndDate2 147.44 24.574 6 184.24 2.344 0.03319 *
## ---
## Signif. codes: 0 '***' 0.001 '**' 0.01 '*' 0.05 '.' 0.1 ' ' 1## $`emmeans of EndDate2`
## EndDate2 emmean SE df lower.CL upper.CL
## April'19 5.90 0.701 245 4.01 7.80
## Dec'19 5.41 0.591 286 3.81 7.00
## Feb'19 5.40 1.071 253 2.51 8.30
## Mar'19 7.03 1.507 198 2.94 11.11
## May'19 3.62 0.773 229 1.53 5.72
## May'20 5.98 0.543 300 4.51 7.45
## Sep'18 7.41 0.803 293 5.24 9.58
##
## Degrees-of-freedom method: kenward-roger
## Confidence level used: 0.95
## Conf-level adjustment: sidak method for 7 estimates
##
## $`pairwise differences of EndDate2`
## contrast estimate SE df t.ratio p.value
## April'19 - Dec'19 0.4971 0.778 140 0.639 0.9954
## April'19 - Feb'19 0.5002 1.246 212 0.401 0.9997
## April'19 - Mar'19 -1.1235 1.636 184 -0.687 0.9932
## April'19 - May'19 2.2797 0.898 132 2.539 0.1543
## April'19 - May'20 -0.0771 0.813 196 -0.095 1.0000
## April'19 - Sep'18 -1.5105 1.008 227 -1.499 0.7452
## Dec'19 - Feb'19 0.0031 1.127 198 0.003 1.0000
## Dec'19 - Mar'19 -1.6206 1.563 181 -1.037 0.9448
## Dec'19 - May'19 1.7826 0.799 124 2.231 0.2867
## Dec'19 - May'20 -0.5741 0.734 224 -0.782 0.9865
## Dec'19 - Sep'18 -2.0075 0.955 248 -2.102 0.3549
## Feb'19 - Mar'19 -1.6237 1.785 185 -0.910 0.9706
## Feb'19 - May'19 1.7795 1.282 204 1.388 0.8077
## Feb'19 - May'20 -0.5772 1.185 248 -0.487 0.9990
## Feb'19 - Sep'18 -2.0106 1.270 224 -1.583 0.6931
## Mar'19 - May'19 3.4032 1.668 183 2.041 0.3929
## Mar'19 - May'20 1.0464 1.589 201 0.659 0.9946
## Mar'19 - Sep'18 -0.3870 1.580 164 -0.245 1.0000
## May'19 - May'20 -2.3568 0.885 194 -2.663 0.1135
## May'19 - Sep'18 -3.7902 1.083 229 -3.500 0.0099
## May'20 - Sep'18 -1.4334 0.938 277 -1.529 0.7272
##
## Degrees-of-freedom method: kenward-roger
## P value adjustment: tukey method for comparing a family of 7 estimates
N(Sep’18) = 39
N(Feb’19) = 20
N(Mar’19) = 9
N(April’19) = 44
N(May’19) = 35
N(Dec’19) = 70
N(May’20) = 91
N(NA) = 17
N(Total) = 308 / 325
Anxiety Score by this followup
## Type III Analysis of Variance Table with Satterthwaite's method
## Sum Sq Mean Sq NumDF DenDF F value Pr(>F)
## thisfollowup 40.597 10.149 4 161.85 0.8905 0.471## $`emmeans of thisfollowup`
## thisfollowup emmean SE df lower.CL upper.CL
## 1year 5.41 0.485 257 4.157 6.67
## 2year 6.45 0.819 206 4.322 8.57
## 3year 4.14 1.399 167 0.504 7.78
## 6month 5.11 0.494 257 3.832 6.39
## 9month 5.32 1.061 257 2.577 8.07
##
## Degrees-of-freedom method: kenward-roger
## Confidence level used: 0.95
## Conf-level adjustment: sidak method for 5 estimates
##
## $`pairwise differences of thisfollowup`
## contrast estimate SE df t.ratio p.value
## 1year - 2year -1.0339 0.854 135 -1.211 0.7452
## 1year - 3year 1.2723 1.432 145 0.888 0.9008
## 1year - 6month 0.3030 0.613 174 0.495 0.9878
## 1year - 9month 0.0903 1.141 247 0.079 1.0000
## 2year - 3year 2.3062 1.456 114 1.584 0.5109
## 2year - 6month 1.3369 0.938 194 1.426 0.6118
## 2year - 9month 1.1242 1.287 215 0.874 0.9063
## 3year - 6month -0.9693 1.474 167 -0.657 0.9650
## 3year - 9month -1.1820 1.740 193 -0.679 0.9607
## 6month - 9month -0.2127 1.165 255 -0.183 0.9998
##
## Degrees-of-freedom method: kenward-roger
## P value adjustment: tukey method for comparing a family of 5 estimates
N(6month) = 99
N(9month) = 21
N(1year) = 101
N(2year) = 32
N(3year) = 10
N(NA) = 55
N(Total) = 318 / 325
Anxiety Score by Date
## Type III Analysis of Variance Table with Satterthwaite's method
## Sum Sq Mean Sq NumDF DenDF F value Pr(>F)
## EndDate2 66.201 11.034 6 228.75 0.8452 0.5362## $`emmeans of EndDate2`
## EndDate2 emmean SE df lower.CL upper.CL
## April'19 5.57 0.693 274 3.70 7.45
## Dec'19 5.83 0.574 302 4.28 7.38
## Feb'19 5.63 1.053 291 2.78 8.48
## Mar'19 5.63 1.552 241 1.43 9.83
## May'19 5.84 0.766 254 3.77 7.92
## May'20 4.73 0.521 309 3.33 6.14
## Sep'18 6.64 0.786 308 4.52 8.76
##
## Degrees-of-freedom method: kenward-roger
## Confidence level used: 0.95
## Conf-level adjustment: sidak method for 7 estimates
##
## $`pairwise differences of EndDate2`
## contrast estimate SE df t.ratio p.value
## April'19 - Dec'19 -0.25918 0.812 179 -0.319 0.9999
## April'19 - Feb'19 -0.05687 1.247 266 -0.046 1.0000
## April'19 - Mar'19 -0.05320 1.688 232 -0.032 1.0000
## April'19 - May'19 -0.26921 0.939 167 -0.287 1.0000
## April'19 - May'20 0.83840 0.822 241 1.020 0.9491
## April'19 - Sep'18 -1.06496 1.011 263 -1.053 0.9409
## Dec'19 - Feb'19 0.20231 1.138 246 0.178 1.0000
## Dec'19 - Mar'19 0.20598 1.619 225 0.127 1.0000
## Dec'19 - May'19 -0.01002 0.835 148 -0.012 1.0000
## Dec'19 - May'20 1.09758 0.736 266 1.490 0.7504
## Dec'19 - Sep'18 -0.80578 0.947 279 -0.851 0.9791
## Feb'19 - Mar'19 0.00367 1.837 233 0.002 1.0000
## Feb'19 - May'19 -0.21234 1.285 254 -0.165 1.0000
## Feb'19 - May'20 0.89527 1.169 291 0.766 0.9880
## Feb'19 - Sep'18 -1.00809 1.272 268 -0.793 0.9855
## Mar'19 - May'19 -0.21601 1.719 229 -0.126 1.0000
## Mar'19 - May'20 0.89160 1.633 246 0.546 0.9981
## Mar'19 - Sep'18 -1.01176 1.653 206 -0.612 0.9964
## May'19 - May'20 1.10761 0.891 233 1.243 0.8765
## May'19 - Sep'18 -0.79575 1.081 264 -0.736 0.9902
## May'20 - Sep'18 -1.90336 0.925 301 -2.058 0.3804
##
## Degrees-of-freedom method: kenward-roger
## P value adjustment: tukey method for comparing a family of 7 estimates
N(Sep’18) = 39
N(Feb’19) = 21
N(Mar’19) = 9
N(April’19) = 47
N(May’19) = 37
N(Dec’19) = 73
N(May’20) = 92
N(NA) = 7
N(Total) = 318 / 325
Score Diagnoses
Depression
Percent of surveys:
More than minimal depression: 53.24%
More than mild depression: 23.61%
More than moderate depression: 11.57%
More than moderately severe depression: 4.17%
51 subjects out of 216 had a max PHQ score above mild depression.
Anxiety
Percent of surveys:
More than minimal anxiety: 54.05%
More than mild anxiety: 24.77%
More than moderate anxiety: 10.81%
55 subjects out of 222 had a max GAD score above mild anxiety.
Score differences
Depression
Only includes subjects with more than one PHQ data point (n = 76 / 227)
20 / 76 subjects had a max difference in PHQ score greater than 5.
16 / 76 subjects had a max difference in PHQ score greater than 5 AND a max PHQ score above mild depression.
Anxiety
Only includes subjects with more than one GAD data point (n = 76 / 227)
21 / 76 subjects had a max difference in GAD score greater than 5.
17 / 76 subjects had a max difference in GAD score greater than 5 AND a max GAD score above mild anxiety.