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Alive (N=134) |
Melanoma death (N=57) |
Non-melanoma death (N=14) |
Overall (N=205) |
|
---|---|---|---|---|
factor(sex) | ||||
0 | 91 (67.9%) | 28 (49.1%) | 7 (50.0%) | 126 (61.5%) |
1 | 43 (32.1%) | 29 (50.9%) | 7 (50.0%) | 79 (38.5%) |
age | ||||
Mean (SD) | 50.0 (15.9) | 55.1 (17.9) | 65.3 (10.9) | 52.5 (16.7) |
Median [Min, Max] | 52.0 [4.00, 84.0] | 56.0 [14.0, 95.0] | 65.0 [49.0, 86.0] | 54.0 [4.00, 95.0] |
factor(ulcer) | ||||
0 | 92 (68.7%) | 16 (28.1%) | 7 (50.0%) | 115 (56.1%) |
1 | 42 (31.3%) | 41 (71.9%) | 7 (50.0%) | 90 (43.9%) |
thickness | ||||
Mean (SD) | 2.24 (2.33) | 4.31 (3.57) | 3.72 (3.63) | 2.92 (2.96) |
Median [Min, Max] | 1.36 [0.100, 12.9] | 3.54 [0.320, 17.4] | 2.26 [0.160, 12.6] | 1.94 [0.100, 17.4] |
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Characteristic | Alive, N = 134 (65%) |
Melanoma death, N = 57 (28%) |
Non-melanoma death, N = 14 (6.8%) |
Overall, N = 205 |
---|---|---|---|---|
Sex | ||||
0 | 91 / 134 (67.910%) | 28 / 57 (49.123%) | 7 / 14 (50.000%) | 126 / 205 (61.463%) |
1 | 43 / 134 (32.090%) | 29 / 57 (50.877%) | 7 / 14 (50.000%) | 79 / 205 (38.537%) |
Age | ||||
Mean (SD) | 50 (15.92) | 55 (17.91) | 65 (10.90) | 52 (16.67) |
Range | 4, 84 | 14, 95 | 49, 86 | 4, 95 |
Ulcer | ||||
0 | 92 / 134 (68.657%) | 16 / 57 (28.070%) | 7 / 14 (50.000%) | 115 / 205 (56.098%) |
1 | 42 / 134 (31.343%) | 41 / 57 (71.930%) | 7 / 14 (50.000%) | 90 / 205 (43.902%) |
thickness | ||||
Mean (SD) | 2 (2.33) | 4 (3.57) | 4 (3.63) | 3 (2.96) |
Range | 0, 13 | 0, 17 | 0, 13 | 0, 17 |
Characteristic | N = 2001 |
---|---|
Chemotherapy Treatment | |
Drug A | 98 (49.00%) |
Drug B | 102 (51.00%) |
Age | 47 (38, 57) |
Unknown | 11 |
Grade | |
I | 68 (34.00%) |
II | 68 (34.00%) |
III | 64 (32.00%) |
Tumor Response | 61 (31.61%) |
Unknown | 7 |
1
Statistics presented: n (%); Median (IQR)
|
Characteristic | Drug A, N = 98 (49%) |
Drug B, N = 102 (51%) |
Overall, N = 200 |
---|---|---|---|
Age | |||
Mean (SD) | 47 (14.71) | 47 (14.01) | 47 (14.31) |
Range | 6, 78 | 9, 83 | 6, 83 |
Unknown | 7 | 4 | 11 |
Tumor Grade | |||
I | 35 / 98 (35.71%) | 33 / 102 (32.35%) | 68 / 200 (34.00%) |
II | 32 / 98 (32.65%) | 36 / 102 (35.29%) | 68 / 200 (34.00%) |
III | 31 / 98 (31.63%) | 33 / 102 (32.35%) | 64 / 200 (32.00%) |
Tumor Response | 28.0 / 95.0 (29.474%) | 33.0 / 98.0 (33.673%) | 61.0 / 193.0 (31.606%) |
Unknown | 3 | 4 | 7 |
Variable | N | Drug A, N = 981 | Drug B, N = 1021 | p-value2 |
---|---|---|---|---|
Age | 189 | 46 (37, 59) | 48 (39, 56) | 0.7 |
Grade | 200 | 0.9 | ||
I | 35 (35.71%) | 33 (32.35%) | ||
II | 32 (32.65%) | 36 (35.29%) | ||
III | 31 (31.63%) | 33 (32.35%) | ||
Tumor Response | 193 | 28 (29.47%) | 33 (33.67%) | 0.6 |
1
Statistics presented: Median (IQR); n (%)
2
Statistical tests performed: Wilcoxon rank-sum test; chi-square test of independence
|
Characteristic | OR1 | 95% CI1 | p-value |
---|---|---|---|
Chemotherapy Treatment | |||
Drug A | — | — | |
Drug B | 1.13 | 0.60, 2.13 | 0.7 |
Age | 1.02 | 1.00, 1.04 | 0.10 |
Grade | |||
I | — | — | |
II | 0.85 | 0.39, 1.85 | 0.7 |
III | 1.01 | 0.47, 2.15 | >0.9 |
1
OR = Odds Ratio, CI = Confidence Interval
|
Characteristic | Tumor Response | Time to Death | ||||
---|---|---|---|---|---|---|
OR1 | 95% CI1 | p-value | HR1 | 95% CI1 | p-value | |
Chemotherapy Treatment | ||||||
Drug A | — | — | — | — | ||
Drug B | 1.13 | 0.60, 2.13 | 0.7 | 1.30 | 0.88, 1.92 | 0.2 |
Age | 1.02 | 1.00, 1.04 | 0.10 | 1.01 | 0.99, 1.02 | 0.3 |
Grade | ||||||
I | — | — | — | — | ||
II | 0.85 | 0.39, 1.85 | 0.7 | 1.21 | 0.73, 1.99 | 0.5 |
III | 1.01 | 0.47, 2.15 | >0.9 | 1.79 | 1.12, 2.86 | 0.014 |
1
OR = Odds Ratio, CI = Confidence Interval, HR = Hazard Ratio
|
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