Characteristic Univariable Multivariable
N HR1 95% CI1 p-value HR1 95% CI1 p-value
Treatment Groups 2,330
Neoadjuvant Multiagent Chemotherapy
Postop Multiagent Chemotherapy 1.83 1.65, 2.03 <0.001 1.62 1.39, 1.89 <0.001
Age 2,330
<51
>75 1.23 1.00, 1.52 0.045 1.16 0.90, 1.49 0.3
51-75 0.92 0.81, 1.05 0.2 0.97 0.82, 1.15 0.8
Type of Insurance 2,297
Medicaid
Medicare 1.03 0.81, 1.32 0.8
Not Insured 1.28 0.83, 1.95 0.3
Private Insurance/Managed Care/Goverment 0.93 0.73, 1.18 0.5
No High School Degree 2,322
<7.0%
>=21.0% 1.07 0.89, 1.27 0.5
13.0-20.9% 0.99 0.87, 1.14 >0.9
7.0-12.9% 0.95 0.85, 1.07 0.4
TNM Clinical T 2,105
c0
c1 1.47 0.20, 10.8 0.7
c2 1.45 0.20, 10.4 0.7
c3 1.02 0.14, 7.28 >0.9
c4 1.03 0.14, 7.31 >0.9
TNM Clinical N 2,082
c0
c1 1.01 0.91, 1.13 0.8
Clinical Downstaging 1,653
No
Yes 0.64 0.57, 0.73 <0.001 0.74 0.64, 0.84 <0.001

1 HR = Hazard Ratio, CI = Confidence Interval