Analysis from the results of a label free mass spectrometry experiment on paraffin embedded samples stratified as follows:
#Coverage Analysis
On the previously conducted analysis, we could see that filtering the data based on the coverage score was not a good idea as the majority of the proteins had low coverage values. The same analysis was conducted here and the summary statistics of the coverage score for each sample is shown on the table below, and based on that and the plots we can see a similar behaviour regarding the coverage.
## Warning in cbind(stats_1st, summary(coverageDF_1st[[element]])): number of rows
## of result is not a multiple of vector length (arg 2)
| Fib1 | Fib2 | Fib3 | Fib4 | RBC1 | RBC2 | RBC3 | |
|---|---|---|---|---|---|---|---|
| 1 | 3172 | 4471 | 3823 | 0.28000 | 3120 | 3254 | 3305 |
| 2 | 759 | 1106 | 907 | 4.38000 | 851 | 907 | 850 |
| # PSMs | 700 | 952 | 861 | 9.52500 | 616 | 564 | 574 |
| 3 | 142 | 178 | 139 | 15.47617 | 66 | 90 | 78 |
| 4 | 52 | 46 | 55 | 21.46000 | 29 | 24 | 29 |
| 5 | 38 | 19 | 37 | 93.88000 | 11 | 17 | 12 |
| 7 | 22 | 10 | 14 | 0.28000 | 10 | 6 | 12 |
| 8 | 14 | 9 | 13 | 4.38000 | 8 | 6 | 9 |
| 6 | 11 | 9 | 12 | 9.52500 | 4 | 6 | 8 |
| 10 | 10 | 6 | 11 | 15.47617 | 4 | 5 | 6 |
| 13 | 4 | 5 | 6 | 21.46000 | 4 | 4 | 6 |
| 16 | 4 | 5 | 6 | 93.88000 | 4 | 4 | 5 |
| 21 | 4 | 5 | 6 | 0.28000 | 4 | 4 | 5 |
| 70 | 4 | 5 | 5 | 4.38000 | 3 | 4 | 4 |
| 9 | 4 | 4 | 4 | 9.52500 | 3 | 4 | 4 |
| 0.85 | 3 | 4 | 3 | 15.47617 | 3 | 3 | 4 |
| 1.86 | 3 | 4 | 3 | 21.46000 | 3 | 3 | 4 |
| 11 | 3 | 4 | 3 | 93.88000 | 3 | 3 | 4 |
| 13.68 | 3 | 4 | 3 | 0.28000 | 3 | 3 | 3 |
| 14.29 | 3 | 3 | 3 | 4.38000 | 3 | 3 | 3 |
| 17.65 | 3 | 3 | 3 | 9.52500 | 3 | 3 | 3 |
| 2.18 | 3 | 3 | 3 | 15.47617 | 2 | 3 | 3 |
| 20.51 | 3 | 3 | 3 | 21.46000 | 2 | 3 | 3 |
| 23 | 3 | 3 | 3 | 93.88000 | 2 | 3 | 3 |
| 26.09 | 3 | 3 | 3 | 0.28000 | 2 | 3 | 3 |
| 26.5 | 3 | 3 | 2 | 4.38000 | 2 | 3 | 3 |
| 6.15 | 3 | 3 | 2 | 9.52500 | 2 | 3 | 2 |
| 6.84 | 3 | 3 | 2 | 15.47617 | 2 | 2 | 2 |
| 9.09 | 3 | 3 | 2 | 21.46000 | 2 | 2 | 2 |
| 0.41 | 2 | 3 | 2 | 93.88000 | 2 | 2 | 2 |
| 0.68 | 2 | 3 | 2 | 0.28000 | 2 | 2 | 2 |
| 0.96 | 2 | 3 | 2 | 4.38000 | 2 | 2 | 2 |
| 1.12 | 2 | 3 | 2 | 9.52500 | 2 | 2 | 2 |
| 1.25 | 2 | 3 | 2 | 15.47617 | 2 | 2 | 2 |
| 1.38 | 2 | 3 | 2 | 21.46000 | 2 | 2 | 2 |
| 1.44 | 2 | 3 | 2 | 93.88000 | 2 | 2 | 2 |
| 1.61 | 2 | 3 | 2 | 0.28000 | 2 | 2 | 2 |
| 1.64 | 2 | 3 | 2 | 4.38000 | 2 | 2 | 2 |
| 1.85 | 2 | 3 | 2 | 9.52500 | 2 | 2 | 2 |
| 12 | 2 | 3 | 2 | 15.47617 | 2 | 2 | 2 |
| 12.71 | 2 | 3 | 2 | 21.46000 | 2 | 2 | 2 |
| 13.33 | 2 | 3 | 2 | 93.88000 | 2 | 2 | 2 |
| 14.66 | 2 | 3 | 2 | 0.28000 | 2 | 2 | 2 |
| 14.95 | 2 | 3 | 2 | 4.38000 | 2 | 2 | 2 |
| 15.38 | 2 | 3 | 2 | 9.52500 | 2 | 2 | 2 |
| 16.24 | 2 | 2 | 2 | 15.47617 | 2 | 2 | 2 |
| 16.44 | 2 | 2 | 2 | 21.46000 | 2 | 2 | 2 |
| 17 | 2 | 2 | 2 | 93.88000 | 2 | 2 | 2 |
| 17.09 | 2 | 2 | 2 | 0.28000 | 2 | 2 | 2 |
| 19 | 2 | 2 | 2 | 4.38000 | 2 | 2 | 2 |
| 19.05 | 2 | 2 | 2 | 9.52500 | 2 | 2 | 2 |
| 2.03 | 2 | 2 | 2 | 15.47617 | 2 | 2 | 2 |
| 2.47 | 2 | 2 | 2 | 21.46000 | 2 | 2 | 2 |
| 2.49 | 2 | 2 | 2 | 93.88000 | 2 | 2 | 2 |
| 2.52 | 2 | 2 | 2 | 0.28000 | 2 | 2 | 2 |
| 2.66 | 2 | 2 | 2 | 4.38000 | 2 | 2 | 2 |
| 2.82 | 2 | 2 | 2 | 9.52500 | 2 | 2 | 2 |
| 20 | 2 | 2 | 2 | 15.47617 | 2 | 2 | 2 |
| 21.33 | 2 | 2 | 2 | 21.46000 | 2 | 2 | 2 |
| 21.62 | 2 | 2 | 2 | 93.88000 | 2 | 2 | 2 |
| 22.22 | 2 | 2 | 2 | 0.28000 | 2 | 2 | 2 |
| 23.08 | 2 | 2 | 2 | 4.38000 | 2 | 2 | 2 |
| 24.79 | 2 | 2 | 2 | 9.52500 | 2 | 2 | 2 |
| 26.72 | 2 | 2 | 2 | 15.47617 | 2 | 2 | 2 |
| 28 | 2 | 2 | 2 | 21.46000 | 2 | 2 | 2 |
| 29 | 2 | 2 | 2 | 93.88000 | 2 | 2 | 2 |
| 3.04 | 2 | 2 | 2 | 0.28000 | 2 | 2 | 2 |
| 3.06 | 2 | 2 | 2 | 4.38000 | 2 | 2 | 2 |
| 3.13 | 2 | 2 | 2 | 9.52500 | 2 | 2 | 2 |
| 3.35 | 2 | 2 | 2 | 15.47617 | 2 | 2 | 2 |
| 3.4 | 2 | 2 | 2 | 21.46000 | 2 | 2 | 2 |
| 3.57 | 2 | 2 | 2 | 93.88000 | 2 | 2 | 2 |
| 3.64 | 2 | 2 | 2 | 0.28000 | 2 | 2 | 2 |
| 3.85 | 2 | 2 | 2 | 4.38000 | 2 | 2 | 2 |
| 31.42 | 2 | 2 | 2 | 9.52500 | 2 | 2 | 2 |
| 33.33 | 2 | 2 | 2 | 15.47617 | 2 | 2 | 2 |
| 38.46 | 2 | 2 | 2 | 21.46000 | 2 | 2 | 2 |
| 4.02 | 2 | 2 | 2 | 93.88000 | 2 | 2 | 2 |
| 4.15 | 2 | 2 | 2 | 0.28000 | 2 | 2 | 2 |
| 4.27 | 2 | 2 | 2 | 4.38000 | 2 | 2 | 2 |
| 4.37 | 2 | 2 | 2 | 9.52500 | 2 | 2 | 2 |
| 4.48 | 2 | 2 | 2 | 15.47617 | 2 | 2 | 2 |
| 4.95 | 2 | 2 | 2 | 21.46000 | 2 | 2 | 2 |
| 45.3 | 2 | 2 | 2 | 93.88000 | 2 | 2 | 2 |
| 5.39 | 2 | 2 | 2 | 0.28000 | 2 | 2 | 2 |
| 5.74 | 2 | 2 | 2 | 4.38000 | 2 | 2 | 2 |
| 6.92 | 2 | 2 | 2 | 9.52500 | 2 | 2 | 2 |
| 61.72 | 2 | 2 | 2 | 15.47617 | 2 | 2 | 2 |
| 7.27 | 2 | 2 | 2 | 21.46000 | 2 | 2 | 2 |
| 7.53 | 2 | 2 | 2 | 93.88000 | 2 | 2 | 2 |
| 7.69 | 2 | 2 | 2 | 0.28000 | 2 | 2 | 2 |
| 8.79 | 2 | 2 | 2 | 4.38000 | 2 | 2 | 2 |
| 80 | 2 | 2 | 2 | 9.52500 | 2 | 2 | 2 |
| 9.4 | 2 | 2 | 2 | 15.47617 | 2 | 2 | 2 |
| 9.49 | 2 | 2 | 2 | 21.46000 | 2 | 2 | 2 |
| 9.83 | 2 | 2 | 2 | 93.88000 | 2 | 2 | 2 |
| 0.23 | 1 | 2 | 2 | 0.28000 | 2 | 2 | 2 |
| 0.27 | 1 | 2 | 2 | 4.38000 | 2 | 2 | 2 |
| 0.3 | 1 | 2 | 2 | 9.52500 | 2 | 2 | 2 |
| (Other) | 548 | 909 | 737 | 15.47617 | 686 | 732 | 687 |
| Fib1 | Fib2 | Fib3 | Fib4 | Fib5 | RBC1 | RBC2 | RBC3 | RBC4 | RBC5 | |
|---|---|---|---|---|---|---|---|---|---|---|
| Min. | 0.18000 | 0.07000 | 0.0600 | 0.28000 | 0.19000 | 0.19000 | 0.04000 | 0.08000 | 0.30000 | 0.13000 |
| 1st Qu. | 4.73000 | 4.53500 | 4.3800 | 4.38000 | 4.30000 | 5.03000 | 5.01000 | 4.71000 | 5.61750 | 5.02000 |
| Median | 10.17000 | 10.07500 | 9.9800 | 9.52500 | 9.42000 | 10.94000 | 11.69000 | 10.95000 | 11.06500 | 10.90000 |
| Mean | 15.71651 | 15.68055 | 15.3679 | 15.47617 | 14.15617 | 16.54819 | 15.68757 | 15.77537 | 16.03192 | 15.75879 |
| 3rd Qu. | 21.55000 | 23.03000 | 20.6500 | 21.46000 | 19.35000 | 22.54000 | 20.87000 | 21.42250 | 21.89000 | 20.62000 |
| Max. | 97.28000 | 91.55000 | 94.3700 | 93.88000 | 94.37000 | 100.00000 | 100.00000 | 100.00000 | 100.00000 | 100.00000 |