Model 1 - Age1 * LifeIPV Interaction Plot (PWV)
Pulse Wave Velocity - Model 1
m1PWV = lm(PWV~Age1 * LifeIPV * Sex * Race + BMIcat + PovStat,LifeIPVbpPWV)
Model 1 - Age1 * LifeIPV Interaction Plot (PWV)
summary(m1PWV)
##
## Call:
## lm(formula = PWV ~ Age1 * LifeIPV * Sex * Race + BMIcat + PovStat,
## data = LifeIPVbpPWV)
##
## Residuals:
## Pulse wave velocity
## Min 1Q Median 3Q Max
## -4.386 -0.911 -0.122 0.678 12.612
##
## Coefficients:
## Estimate Std. Error t value Pr(>|t|)
## (Intercept) 3.27399 1.20583 2.72 0.0069
## Age1 0.06478 0.02462 2.63 0.0089
## LifeIPV1 -2.87879 1.83320 -1.57 0.1172
## SexMen 1.29768 1.74084 0.75 0.4565
## RaceAfrAm 0.36299 1.61561 0.22 0.8224
## BMIcatObese 0.17165 0.18169 0.94 0.3455
## PovStatBelow 0.13638 0.17174 0.79 0.4277
## Age1:LifeIPV1 0.07849 0.03714 2.11 0.0353
## Age1:SexMen -0.01819 0.03585 -0.51 0.6123
## LifeIPV1:SexMen 6.98646 8.04250 0.87 0.3856
## Age1:RaceAfrAm 0.01429 0.03272 0.44 0.6626
## LifeIPV1:RaceAfrAm 0.98291 2.45025 0.40 0.6886
## SexMen:RaceAfrAm -0.40376 2.33031 -0.17 0.8625
## Age1:LifeIPV1:SexMen -0.15772 0.15963 -0.99 0.3238
## Age1:LifeIPV1:RaceAfrAm -0.02930 0.04969 -0.59 0.5557
## Age1:SexMen:RaceAfrAm 0.00135 0.04768 0.03 0.9774
## LifeIPV1:SexMen:RaceAfrAm -2.90386 8.61869 -0.34 0.7364
## Age1:LifeIPV1:SexMen:RaceAfrAm 0.06582 0.17272 0.38 0.7034
##
## Residual standard error: 1.57 on 354 degrees of freedom
## Multiple R-squared: 0.258, Adjusted R-squared: 0.223
## F-statistic: 7.25 on 17 and 354 DF, p-value: 2.9e-15
Pulse Wave Velocity - Model 2 - mean arterial pressure (MAP) included as covariate
No BP adjustments for MAP
m2PWV = lm(PWV~Age1 * LifeIPV * Sex * Race + BMIcat + PovStat + MAP,LifeIPVbpPWV)
summary(m2PWV)
##
## Call:
## lm(formula = PWV ~ Age1 * LifeIPV * Sex * Race + BMIcat + PovStat +
## MAP, data = LifeIPVbpPWV)
##
## Residuals:
## Pulse wave velocity
## Min 1Q Median 3Q Max
## -4.740 -0.852 -0.166 0.600 12.712
##
## Coefficients:
## Estimate Std. Error t value Pr(>|t|)
## (Intercept) 1.56962 1.30023 1.21 0.2282
## Age1 0.05872 0.02436 2.41 0.0164
## LifeIPV1 -2.62908 1.81055 -1.45 0.1474
## SexMen 1.15340 1.71836 0.67 0.5025
## RaceAfrAm 0.48773 1.59466 0.31 0.7599
## BMIcatObese 0.06842 0.18208 0.38 0.7073
## PovStatBelow 0.06861 0.17075 0.40 0.6880
## MAP 0.02479 0.00763 3.25 0.0013
## Age1:LifeIPV1 0.07159 0.03671 1.95 0.0520
## Age1:SexMen -0.01688 0.03538 -0.48 0.6336
## LifeIPV1:SexMen 6.13097 7.94032 0.77 0.4406
## Age1:RaceAfrAm 0.01071 0.03231 0.33 0.7405
## LifeIPV1:RaceAfrAm 0.43817 2.42359 0.18 0.8566
## SexMen:RaceAfrAm -0.77752 2.30231 -0.34 0.7358
## Age1:LifeIPV1:SexMen -0.13886 0.15762 -0.88 0.3789
## Age1:LifeIPV1:RaceAfrAm -0.01824 0.04915 -0.37 0.7108
## Age1:SexMen:RaceAfrAm 0.00896 0.04711 0.19 0.8492
## LifeIPV1:SexMen:RaceAfrAm -0.39885 8.53935 -0.05 0.9628
## Age1:LifeIPV1:SexMen:RaceAfrAm 0.01170 0.17124 0.07 0.9456
##
## Residual standard error: 1.55 on 353 degrees of freedom
## Multiple R-squared: 0.28, Adjusted R-squared: 0.243
## F-statistic: 7.62 on 18 and 353 DF, p-value: <2e-16
Pulse Wave Velocity - Model 3 - mean arterial pressure (MAP) included as covariate
sBP and dBP adjustments for MAP
m3PWV = lm(PWV~Age1 * LifeIPV * Sex * Race + BMIcat + PovStat + adjMAP,LifeIPVbpPWV)
summary(m3PWV)
##
## Call:
## lm(formula = PWV ~ Age1 * LifeIPV * Sex * Race + BMIcat + PovStat +
## adjMAP, data = LifeIPVbpPWV)
##
## Residuals:
## Pulse wave velocity
## Min 1Q Median 3Q Max
## -4.863 -0.826 -0.184 0.595 12.585
##
## Coefficients:
## Estimate Std. Error t value Pr(>|t|)
## (Intercept) 1.48899 1.27168 1.17 0.24243
## Age1 0.05500 0.02429 2.26 0.02414
## LifeIPV1 -2.50884 1.80140 -1.39 0.16458
## SexMen 1.08656 1.70907 0.64 0.52534
## RaceAfrAm 0.51987 1.58582 0.33 0.74324
## BMIcatObese 0.02580 0.18231 0.14 0.88755
## PovStatBelow 0.05659 0.16980 0.33 0.73911
## adjMAP 0.02766 0.00722 3.83 0.00015
## Age1:LifeIPV1 0.06912 0.03653 1.89 0.05928
## Age1:SexMen -0.01543 0.03518 -0.44 0.66125
## LifeIPV1:SexMen 6.31311 7.89354 0.80 0.42437
## Age1:RaceAfrAm 0.00971 0.03213 0.30 0.76274
## LifeIPV1:RaceAfrAm 0.32660 2.41037 0.14 0.89230
## SexMen:RaceAfrAm -0.80605 2.28900 -0.35 0.72494
## Age1:LifeIPV1:SexMen -0.14265 0.15668 -0.91 0.36321
## Age1:LifeIPV1:RaceAfrAm -0.01637 0.04887 -0.33 0.73791
## Age1:SexMen:RaceAfrAm 0.00974 0.04684 0.21 0.83534
## LifeIPV1:SexMen:RaceAfrAm -0.30410 8.48416 -0.04 0.97143
## Age1:LifeIPV1:SexMen:RaceAfrAm 0.00899 0.17013 0.05 0.95790
##
## Residual standard error: 1.54 on 353 degrees of freedom
## Multiple R-squared: 0.288, Adjusted R-squared: 0.252
## F-statistic: 7.93 on 18 and 353 DF, p-value: <2e-16
Pulse Wave Velocity - Model 4 - mean arterial pressure (MAP) included as covariate
sBP adjustments for MAP
m4PWV = lm(PWV~Age1 * LifeIPV * Sex * Race + BMIcat + PovStat + MAP_adjsBP,LifeIPVbpPWV)
summary(m4PWV)
##
## Call:
## lm(formula = PWV ~ Age1 * LifeIPV * Sex * Race + BMIcat + PovStat +
## MAP_adjsBP, data = LifeIPVbpPWV)
##
## Residuals:
## Pulse wave velocity
## Min 1Q Median 3Q Max
## -4.807 -0.842 -0.179 0.591 12.652
##
## Coefficients:
## Estimate Std. Error t value Pr(>|t|)
## (Intercept) 1.49399 1.28656 1.16 0.2463
## Age1 0.05680 0.02432 2.34 0.0201
## LifeIPV1 -2.56564 1.80558 -1.42 0.1562
## SexMen 1.11802 1.71333 0.65 0.5145
## RaceAfrAm 0.50594 1.58989 0.32 0.7505
## BMIcatObese 0.04562 0.18219 0.25 0.8024
## PovStatBelow 0.06135 0.17026 0.36 0.7188
## MAP_adjsBP 0.02671 0.00747 3.57 0.0004
## Age1:LifeIPV1 0.07025 0.03661 1.92 0.0558
## Age1:SexMen -0.01615 0.03527 -0.46 0.6473
## LifeIPV1:SexMen 6.20050 7.91505 0.78 0.4339
## Age1:RaceAfrAm 0.01015 0.03221 0.32 0.7529
## LifeIPV1:RaceAfrAm 0.37257 2.41653 0.15 0.8776
## SexMen:RaceAfrAm -0.79934 2.29517 -0.35 0.7278
## Age1:LifeIPV1:SexMen -0.14028 0.15712 -0.89 0.3725
## Age1:LifeIPV1:RaceAfrAm -0.01709 0.04900 -0.35 0.7274
## Age1:SexMen:RaceAfrAm 0.00950 0.04696 0.20 0.8397
## LifeIPV1:SexMen:RaceAfrAm -0.29917 8.51010 -0.04 0.9720
## Age1:LifeIPV1:SexMen:RaceAfrAm 0.00922 0.17065 0.05 0.9569
##
## Residual standard error: 1.54 on 353 degrees of freedom
## Multiple R-squared: 0.284, Adjusted R-squared: 0.248
## F-statistic: 7.79 on 18 and 353 DF, p-value: <2e-16
Pulse Wave Velocity - Model 5 - mean arterial pressure (MAP) included as covariate
dBP adjustments for MAP
m5PWV = lm(PWV~Age1 * LifeIPV * Sex * Race + BMIcat + PovStat + MAP_adjdBP,LifeIPVbpPWV)
summary(m5PWV)
##
## Call:
## lm(formula = PWV ~ Age1 * LifeIPV * Sex * Race + BMIcat + PovStat +
## MAP_adjdBP, data = LifeIPVbpPWV)
##
## Residuals:
## Pulse wave velocity
## Min 1Q Median 3Q Max
## -4.807 -0.842 -0.179 0.591 12.652
##
## Coefficients:
## Estimate Std. Error t value Pr(>|t|)
## (Intercept) 1.49399 1.28656 1.16 0.2463
## Age1 0.05680 0.02432 2.34 0.0201
## LifeIPV1 -2.56564 1.80558 -1.42 0.1562
## SexMen 1.11802 1.71333 0.65 0.5145
## RaceAfrAm 0.50594 1.58989 0.32 0.7505
## BMIcatObese 0.04562 0.18219 0.25 0.8024
## PovStatBelow 0.06135 0.17026 0.36 0.7188
## MAP_adjdBP 0.02671 0.00747 3.57 0.0004
## Age1:LifeIPV1 0.07025 0.03661 1.92 0.0558
## Age1:SexMen -0.01615 0.03527 -0.46 0.6473
## LifeIPV1:SexMen 6.20050 7.91505 0.78 0.4339
## Age1:RaceAfrAm 0.01015 0.03221 0.32 0.7529
## LifeIPV1:RaceAfrAm 0.37257 2.41653 0.15 0.8776
## SexMen:RaceAfrAm -0.79934 2.29517 -0.35 0.7278
## Age1:LifeIPV1:SexMen -0.14028 0.15712 -0.89 0.3725
## Age1:LifeIPV1:RaceAfrAm -0.01709 0.04900 -0.35 0.7274
## Age1:SexMen:RaceAfrAm 0.00950 0.04696 0.20 0.8397
## LifeIPV1:SexMen:RaceAfrAm -0.29917 8.51010 -0.04 0.9720
## Age1:LifeIPV1:SexMen:RaceAfrAm 0.00922 0.17065 0.05 0.9569
##
## Residual standard error: 1.54 on 353 degrees of freedom
## Multiple R-squared: 0.284, Adjusted R-squared: 0.248
## F-statistic: 7.79 on 18 and 353 DF, p-value: <2e-16