Lucrare de licență
.
Samira Akari
https://rpubs.com/alex_istrate/
1 Partea generală
2 Partea specială
2.1 Introducere
2.1.1 Obiective
2.2 Material și metode
2.2.1 Analiza statistică a datelor
Pentru variabilele calitative, am folosit pie-uri sau bar-chart-uri și am calculat frecvențele absolute și relative ale categoriilor formate. Pentru a descrie relațiile dintre variabilele calitative am folosit testele Fisher și Odds-Ratio (OR) cu IC95% sau Chi² și Cramer V. Am prezentat grafic rezultatele sub forma unor bar-chart-uri.
Pentru a studia relațiile dintre variabilele cantitative și cele binare, am folosit testul Mann-Whitney (MW). Am prezentat valorile p generate de aceste teste precum și mediile ±DS ale grupurilor și diferența mediilor cu IC95% asociat. Pentru a descrie relațiile dintre variabilele calitative am folosit testul Chi² sau Fisher și indicatorii Cramer V și Odds-Ratio (OR) cu IC95%. Am prezentat grafic rezultatele sub forma unor bar-chart-uri.
Pentru a studia relațiile dintre variabilele cantitative am folosit coeficientul de corelație Spearman (R), cu valoarea p asociata și am prezentat grafic relațiile sub forma unor scatter-plot-uri pe care am adăugat linia de regresie.
Am folosit WPS Office 2019 pentru managementul bazei de date. Pentru toate analizele statistice și graficele ulterioare am folosit R version 4.0.0 (2020-04-24) [1]. Am considerat p < 0.05 ca fiind semnificativ statistic și p < 0.1 ca prezentând doar o tendință spre semnificativitate statistică.
2.3 Rezultate
Tables: Toate variabilele, in functie de Sursa datelor
Variabila | Detalii | Ambulator | Spital | Total | Teste statistice |
Sursa datelor | 46 (14.6%) | 269 (85.4%) | 315 | ||
Sex | F | 19 (42.2%) | 87 (34.1%) | 106 (35.3%) | OR=1.41 [0.74, 2.69] (p=0.313) |
M | 26 (57.8%) | 168 (65.9%) | 194 (64.7%) | ||
Varsta | M (min:max) | 60 (40:89) | 64 (10:88) | 64 (10:89) | MW: p=0.061 |
μ ±DS | 60.33 ±13.1 | 63.39 ±14.6 | 62.94 ±14.4 | ||
Sectie | CHIRURGIE GENERALA I | 0 (NA) | 11 (4.3%) | 11 (4.3%) | V=NA (p>0.999) |
CHIRURGIE GENERALA II | 0 (NA) | 17 (6.6%) | 17 (6.6%) | ||
CHIRURGIE GENERALA III | 0 (NA) | 9 (3.5%) | 9 (3.5%) | ||
GASTROENTEROLOGIE I | 0 (NA) | 42 (16.4%) | 42 (16.4%) | ||
GASTROENTEROLOGIE II | 0 (NA) | 49 (19.1%) | 49 (19.1%) | ||
GASTROENTEROLOGIE III | 0 (NA) | 73 (28.5%) | 73 (28.5%) | ||
GASTROENTEROLOGIE IV | 0 (NA) | 55 (21.5%) | 55 (21.5%) | ||
Durata internarii | M (min:max) | 12 (1:387) | 12 (1:387) | ||
μ ±DS | 22.47 ±46.8 | 22.47 ±46.8 | |||
Scor Q | M (min:max) | 2 (-2:3) | 1 (-2:3) | 1 (-2:3) | MW: p=0.063 |
μ ±DS | 1.07 ±1.6 | 0.877 ±1.17 | 0.905 ±1.24 | ||
Scor Q 1-3 | 33 (71.7%) | 203 (75.5%) | 236 (74.9%) | OR=1.21 [0.60, 2.44] (p=0.584) | |
μ ±DS = Media (deviația standard); M (min:max) = Mediana (min:max); MW = Test Mann-Whitney; OR = odds-ratio [cu IC 95%] și p calculat prin testul Fisher); V = Cramér V (p calculat prin testul Chi²); | |||||
Variabila | Detalii | Ambulator | Spital | Total | Teste statistice |
Sursa datelor | 46 (14.6%) | 269 (85.4%) | 315 | ||
Frotiu: PMN | <10 PMN | 8 (18.2%) | 67 (26.4%) | 75 (25.2%) | V=0.13 (p=0.090) |
>25 PMN | 29 (65.9%) | 122 (48.0%) | 151 (50.7%) | ||
10-25 PMN | 7 (15.9%) | 65 (25.6%) | 72 (24.2%) | ||
Frotiu: CES | <10 CES | 7 (16.7%) | 15 (5.9%) | 22 (7.5%) | V=0.18 (p=0.007) |
10-25 CES | 21 (50.0%) | 99 (39.1%) | 120 (40.7%) | ||
>25 CES | 14 (33.3%) | 139 (54.9%) | 153 (51.9%) | ||
Frotiu: contaminare | contaminare cu saliva flora bacteriana mixta | 0 | 11 (4.1%) | 11 (3.5%) | V=0.18 (p=0.040) |
contaminare cu saliva flora bacteriana polimorfa | 5 (10.9%) | 72 (26.8%) | 77 (24.4%) | ||
contamina cu saliva flora bacteriana redusa | 0 | 1 (0.4%) | 1 (0.3%) | ||
contaminare cu saliva | 0 | 6 (2.2%) | 6 (1.9%) | ||
nu | 41 (89.1%) | 179 (66.5%) | 220 (69.8%) | ||
μ ±DS = Media (deviația standard); M (min:max) = Mediana (min:max); MW = Test Mann-Whitney; OR = odds-ratio [cu IC 95%] și p calculat prin testul Fisher); V = Cramér V (p calculat prin testul Chi²); | |||||
Variabila | Detalii | Ambulator | Spital | Total | Teste statistice |
Sursa datelor | 46 (14.6%) | 269 (85.4%) | 315 | ||
Rezultat cultura | contaminare | 12 (26.7%) | 0 | 12 (3.8%) | V=0.52 (p<0.001) |
multiplu pozitiv | 19 (42.2%) | 83 (30.9%) | 102 (32.5%) | ||
negativ | 3 (6.7%) | 99 (36.8%) | 102 (32.5%) | ||
pozitiv | 11 (24.4%) | 87 (32.3%) | 98 (31.2%) | ||
Tulpina | Acinetobacter baumannii | 1 (4.3%) | 22 (14.5%) | 23 (13.1%) | V=0.56 (p<0.001) |
Acinetobacter lwoffii | 0 | 2 (1.3%) | 2 (1.1%) | ||
Burkholderia cepacia | 0 | 2 (1.3%) | 2 (1.1%) | ||
Corynebacterium spp | 1 (4.3%) | 2 (1.3%) | 3 (1.7%) | ||
Enterobacter spp | 0 | 7 (4.6%) | 7 (4.0%) | ||
Enterococcus faecalis | 0 | 2 (1.3%) | 2 (1.1%) | ||
Enterococcus faecium | 0 | 2 (1.3%) | 2 (1.1%) | ||
Enterococcus spp | 0 | 2 (1.3%) | 2 (1.1%) | ||
Escherichia coli | 0 | 14 (9.2%) | 14 (8.0%) | ||
Haemophilus influenzae | 3 (13.0%) | 9 (5.9%) | 12 (6.9%) | ||
Haemophilus parainfluenzae | 2 (8.7%) | 3 (2.0%) | 5 (2.9%) | ||
Haemophilus spp | 3 (13.0%) | 0 | 3 (1.7%) | ||
Klebsiella spp | 3 (13.0%) | 33 (21.7%) | 36 (20.6%) | ||
Moraxella spp | 1 (4.3%) | 3 (2.0%) | 4 (2.3%) | ||
Morganella spp | 0 | 1 (0.7%) | 1 (0.6%) | ||
Pasteurella spp | 0 | 1 (0.7%) | 1 (0.6%) | ||
Proteus vulgaris | 0 | 2 (1.3%) | 2 (1.1%) | ||
Pseudomonas aeruginosa | 2 (8.7%) | 19 (12.5%) | 21 (12.0%) | ||
Pseudomonas fluorescens | 4 (17.4%) | 1 (0.7%) | 5 (2.9%) | ||
Serratia spp | 0 | 5 (3.3%) | 5 (2.9%) | ||
Staphylococcus aureus | 2 (8.7%) | 14 (9.2%) | 16 (9.1%) | ||
Staphylococcus epidermidis | 0 | 2 (1.3%) | 2 (1.1%) | ||
Stenotrophomonas maltophilia | 1 (4.3%) | 4 (2.6%) | 5 (2.9%) | ||
Streptococcus pneumoniae | 0 | 0 | 0 | ||
μ ±DS = Media (deviația standard); M (min:max) = Mediana (min:max); MW = Test Mann-Whitney; OR = odds-ratio [cu IC 95%] și p calculat prin testul Fisher); V = Cramér V (p calculat prin testul Chi²); | |||||
Variabila | Detalii | Ambulator | Spital | Total | Teste statistice |
Sursa datelor | 46 (14.6%) | 269 (85.4%) | 315 | ||
Ampicilina | R | 6 (42.9%) | 48 (64.0%) | 54 (60.7%) | V=0.20 (p=0.173) |
I | 0 | 3 (4.0%) | 3 (3.4%) | ||
S | 8 (57.1%) | 24 (32.0%) | 32 (36.0%) | ||
Amoxicilina / acid clavulanic | R | 0 | 35 (49.3%) | 35 (46.1%) | V=0.25 (p=0.033) |
I | 0 | 0 | 0 | ||
S | 5 (100%) | 36 (50.7%) | 41 (53.9%) | ||
Piperacilina / tazobactam | R | 0 | 22 (28.6%) | 22 (26.8%) | V=0.43 (p<0.001) |
I | 2 (40.0%) | 2 (2.6%) | 4 (4.9%) | ||
S | 3 (60.0%) | 53 (68.8%) | 56 (68.3%) | ||
Ticarcilina / acid clavulanic | R | 2 (100%) | 13 (56.5%) | 15 (60.0%) | V=0.24 (p=0.485) |
I | 0 | 1 (4.3%) | 1 (4.0%) | ||
S | 0 | 9 (39.1%) | 9 (36.0%) | ||
Cefazolina | R | 0 | 8 (30.8%) | 8 (28.6%) | V=0.19 (p=0.600) |
I | 0 | 1 (3.8%) | 1 (3.6%) | ||
S | 2 (100%) | 17 (65.4%) | 19 (67.9%) | ||
Cefalexin | R | 0 (NA) | 12 (85.7%) | 12 (85.7%) | V=NA (p>0.999) |
I | 0 (NA) | 0 | 0 | ||
S | 0 (NA) | 2 (14.3%) | 2 (14.3%) | ||
Cefoxitin | R | 2 (50.0%) | 21 (44.7%) | 23 (45.1%) | V=0.03 (p=0.837) |
I | 0 | 0 | 0 | ||
S | 2 (50.0%) | 26 (55.3%) | 28 (54.9%) | ||
Cefuroxim | R | 0 | 24 (45.3%) | 24 (37.5%) | V=0.35 (p=0.005) |
I | 0 | 0 | 0 | ||
S | 11 (100%) | 29 (54.7%) | 40 (62.5%) | ||
Cefotaxim | R | 0 | 15 (22.7%) | 15 (19.2%) | V=0.50 (p<0.001) |
I | 3 (25.0%) | 0 | 3 (3.8%) | ||
S | 9 (75.0%) | 51 (77.3%) | 60 (76.9%) | ||
Ceftazidim | R | 0 | 21 (23.3%) | 21 (21.2%) | V=0.16 (p=0.103) |
I | 0 | 0 | 0 | ||
S | 9 (100%) | 69 (76.7%) | 78 (78.8%) | ||
Cefoperazona / sulbactam | R | 0 (NA) | 18 (94.7%) | 18 (94.7%) | V=NA (p>0.999) |
I | 0 (NA) | 0 | 0 | ||
S | 0 (NA) | 1 (5.3%) | 1 (5.3%) | ||
Ceftriaxona | R | 0 | 16 (29.1%) | 16 (23.9%) | V=0.51 (p<0.001) |
I | 3 (25.0%) | 0 | 3 (4.5%) | ||
S | 9 (75.0%) | 39 (70.9%) | 48 (71.6%) | ||
Cefoperazona | R | 3 (100%) | 22 (88.0%) | 25 (89.3%) | V=0.12 (p=0.525) |
I | 0 | 0 | 0 | ||
S | 0 | 3 (12.0%) | 3 (10.7%) | ||
Cefepim | R | 0 | 17 (32.7%) | 17 (29.3%) | V=0.22 (p=0.096) |
I | 0 | 0 | 0 | ||
S | 6 (100%) | 35 (67.3%) | 41 (70.7%) | ||
Ertapenem | R | 0 | 5 (14.7%) | 5 (14.3%) | V=0.08 (p=0.899) |
I | 0 | 1 (2.9%) | 1 (2.9%) | ||
S | 1 (100%) | 28 (82.4%) | 29 (82.9%) | ||
Imipenem | R | 0 | 23 (21.7%) | 23 (19.3%) | V=0.28 (p=0.010) |
I | 2 (15.4%) | 2 (1.9%) | 4 (3.4%) | ||
S | 11 (84.6%) | 81 (76.4%) | 92 (77.3%) | ||
Meropenem | R | 0 | 32 (28.8%) | 32 (25.4%) | V=0.29 (p=0.005) |
I | 2 (13.3%) | 2 (1.8%) | 4 (3.2%) | ||
S | 13 (86.7%) | 77 (69.4%) | 90 (71.4%) | ||
Aztreonam | R | 0 (NA) | 7 (23.3%) | 7 (23.3%) | V=NA (p>0.999) |
I | 0 (NA) | 11 (36.7%) | 11 (36.7%) | ||
S | 0 (NA) | 12 (40.0%) | 12 (40.0%) | ||
Benzilpenicilina | R | 3 (75.0%) | 16 (69.6%) | 19 (70.4%) | V=0.15 (p=0.725) |
I | 1 (25.0%) | 4 (17.4%) | 5 (18.5%) | ||
S | 0 | 3 (13.0%) | 3 (11.1%) | ||
Ampicilina / sulbactam | R | 0 | 9 (60.0%) | 9 (56.2%) | V=0.29 (p=0.242) |
I | 0 | 0 | 0 | ||
S | 1 (100%) | 6 (40.0%) | 7 (43.8%) | ||
Oxacilina | R | 0 | 9 (56.2%) | 9 (40.9%) | V=0.51 (p=0.017) |
I | 0 | 0 | 0 | ||
S | 6 (100%) | 7 (43.8%) | 13 (59.1%) | ||
Piperacilina | R | 0 | 12 (42.9%) | 12 (35.3%) | V=0.59 (p=0.003) |
I | 2 (33.3%) | 0 | 2 (5.9%) | ||
S | 4 (66.7%) | 16 (57.1%) | 20 (58.8%) | ||
Penicilina | R | 0 | 2 (100%) | 2 (66.7%) | V=>0.99 (p=0.083) |
I | 0 | 0 | 0 | ||
S | 1 (100%) | 0 | 1 (33.3%) | ||
Ciprofloxacina | R | 0 | 39 (29.1%) | 39 (25.2%) | V=0.25 (p=0.007) |
I | 1 (4.8%) | 1 (0.7%) | 2 (1.3%) | ||
S | 20 (95.2%) | 94 (70.1%) | 114 (73.5%) | ||
Ofloxacina | R | 0 | 4 (11.1%) | 4 (7.7%) | V=0.19 (p=0.165) |
I | 0 | 0 | 0 | ||
S | 16 (100%) | 32 (88.9%) | 48 (92.3%) | ||
Levofloxacina | R | 0 | 34 (29.6%) | 34 (26.0%) | V=0.26 (p=0.014) |
I | 1 (6.2%) | 1 (0.9%) | 2 (1.5%) | ||
S | 15 (93.8%) | 80 (69.6%) | 95 (72.5%) | ||
Moxifloxacina | R | 0 | 14 (40.0%) | 14 (37.8%) | V=0.20 (p=0.486) |
I | 0 | 1 (2.9%) | 1 (2.7%) | ||
S | 2 (100%) | 20 (57.1%) | 22 (59.5%) | ||
Norfloxacina | R | 0 | 21 (56.8%) | 21 (53.8%) | V=0.25 (p=0.117) |
I | 0 | 0 | 0 | ||
S | 2 (100%) | 16 (43.2%) | 18 (46.2%) | ||
Vancomicina | R | 0 | 3 (10.3%) | 3 (8.1%) | V=0.16 (p=0.343) |
I | 0 | 0 | 0 | ||
S | 8 (100%) | 26 (89.7%) | 34 (91.9%) | ||
Teicoplanin | R | 0 | 3 (13.0%) | 3 (12.0%) | V=0.11 (p=0.586) |
I | 0 | 0 | 0 | ||
S | 2 (100%) | 20 (87.0%) | 22 (88.0%) | ||
Amikacina | R | 0 | 16 (22.9%) | 16 (20.8%) | V=0.20 (p=0.214) |
I | 0 | 6 (8.6%) | 6 (7.8%) | ||
S | 7 (100%) | 48 (68.6%) | 55 (71.4%) | ||
Gentamicina | R | 0 | 18 (19.6%) | 18 (17.5%) | V=0.17 (p=0.207) |
I | 0 | 3 (3.3%) | 3 (2.9%) | ||
S | 11 (100%) | 71 (77.2%) | 82 (79.6%) | ||
Tobramicina | R | 0 | 15 (17.4%) | 15 (15.6%) | V=0.15 (p=0.150) |
I | 0 | 0 | 0 | ||
S | 10 (100%) | 71 (82.6%) | 81 (84.4%) | ||
Netilmicina | R | 0 | 3 (18.8%) | 3 (17.6%) | V=0.12 (p=0.633) |
I | 0 | 0 | 0 | ||
S | 1 (100%) | 13 (81.2%) | 14 (82.4%) | ||
Tetraciclina | R | 6 (33.3%) | 21 (37.5%) | 27 (36.5%) | V=0.04 (p=0.749) |
I | 0 | 0 | 0 | ||
S | 12 (66.7%) | 35 (62.5%) | 47 (63.5%) | ||
Minociclina | R | 0 | 2 (12.5%) | 2 (9.5%) | V=0.23 (p=0.579) |
I | 0 | 1 (6.2%) | 1 (4.8%) | ||
S | 5 (100%) | 13 (81.2%) | 18 (85.7%) | ||
Tigeciclina | R | 0 | 0 | 0 | V=NA (p>0.999) |
I | 0 | 0 | 0 | ||
S | 1 (100%) | 21 (100%) | 22 (100%) | ||
Kanamicina | R | 0 | 2 (100%) | 2 (66.7%) | V=>0.99 (p=0.083) |
I | 0 | 0 | 0 | ||
S | 1 (100%) | 0 | 1 (33.3%) | ||
Eritromicina | R | 3 (30.0%) | 11 (40.7%) | 14 (37.8%) | V=0.28 (p=0.232) |
I | 1 (10.0%) | 0 | 1 (2.7%) | ||
S | 6 (60.0%) | 16 (59.3%) | 22 (59.5%) | ||
Azitromicina | R | 0 | 6 (25.0%) | 6 (18.2%) | V=0.29 (p=0.097) |
I | 0 | 0 | 0 | ||
S | 9 (100%) | 18 (75.0%) | 27 (81.8%) | ||
Claritromicina | R | 0 | 6 (37.5%) | 6 (35.3%) | V=0.18 (p=0.446) |
I | 0 | 0 | 0 | ||
S | 1 (100%) | 10 (62.5%) | 11 (64.7%) | ||
Clindamicina | R | 3 (37.5%) | 7 (43.8%) | 10 (41.7%) | V=0.06 (p=0.770) |
I | 0 | 0 | 0 | ||
S | 5 (62.5%) | 9 (56.2%) | 14 (58.3%) | ||
Ticarcilina | R | 7 (100%) | 12 (92.3%) | 19 (95.0%) | V=0.17 (p=0.452) |
I | 0 | 0 | 0 | ||
S | 0 | 1 (7.7%) | 1 (5.0%) | ||
Streptomicina | R | 0 (NA) | 2 (66.7%) | 2 (66.7%) | V=NA (p>0.999) |
I | 0 (NA) | 0 | 0 | ||
S | 0 (NA) | 1 (33.3%) | 1 (33.3%) | ||
Quinupristin / dalfopristin | R | 0 (NA) | 3 (75.0%) | 3 (75.0%) | V=NA (p>0.999) |
I | 0 (NA) | 0 | 0 | ||
S | 0 (NA) | 1 (25.0%) | 1 (25.0%) | ||
Fosfomicina | R | 0 | 4 (12.9%) | 4 (12.5%) | V=0.07 (p=0.701) |
I | 0 | 0 | 0 | ||
S | 1 (100%) | 27 (87.1%) | 28 (87.5%) | ||
Colistin | R | 0 | 3 (7.7%) | 3 (6.5%) | V=0.11 (p=0.448) |
I | 0 | 0 | 0 | ||
S | 7 (100%) | 36 (92.3%) | 43 (93.5%) | ||
Cloramfenicol | R | 0 | 0 | 0 | V=NA (p>0.999) |
I | 0 | 0 | 0 | ||
S | 16 (100%) | 41 (100%) | 57 (100%) | ||
Nitrofurantoin | R | 0 (NA) | 6 (42.9%) | 6 (42.9%) | V=NA (p>0.999) |
I | 0 (NA) | 0 | 0 | ||
S | 0 (NA) | 8 (57.1%) | 8 (57.1%) | ||
Trimetoprim / sulfametoxazol | R | 8 (36.4%) | 35 (28.5%) | 43 (29.7%) | V=0.06 (p=0.454) |
I | 0 | 0 | 0 | ||
S | 14 (63.6%) | 88 (71.5%) | 102 (70.3%) | ||
Linezolid | R | 0 | 0 | 0 | V=NA (p>0.999) |
I | 0 | 0 | 0 | ||
S | 8 (100%) | 26 (100%) | 34 (100%) | ||
Acid fusidic | R | 0 | 1 (7.1%) | 1 (6.7%) | V=0.07 (p=0.782) |
I | 0 | 0 | 0 | ||
S | 1 (100%) | 13 (92.9%) | 14 (93.3%) | ||
Rifampicina | R | 0 | 4 (20.0%) | 4 (19.0%) | V=0.69 (p=0.007) |
I | 1 (100%) | 1 (5.0%) | 2 (9.5%) | ||
S | 0 | 15 (75.0%) | 15 (71.4%) | ||
μ ±DS = Media (deviația standard); M (min:max) = Mediana (min:max); MW = Test Mann-Whitney; OR = odds-ratio [cu IC 95%] și p calculat prin testul Fisher); V = Cramér V (p calculat prin testul Chi²); | |||||
Table: Toate variabilele, in functie de Scor Q 2-3
Variabila | Detalii | nu | da | Total | Teste statistice |
Scor Q 1-3 | 79 (25.1%) | 236 (74.9%) | 315 | ||
Sursa datelor | Ambulator | 13 (16.5%) | 33 (14.0%) | 46 (14.6%) | OR=1.21 [0.60, 2.44] (p=0.584) |
Spital | 66 (83.5%) | 203 (86.0%) | 269 (85.4%) | ||
Sex | F | 35 (44.3%) | 71 (32.1%) | 106 (35.3%) | OR=1.68 [0.99, 2.84] (p=0.056) |
M | 44 (55.7%) | 150 (67.9%) | 194 (64.7%) | ||
Varsta | M (min:max) | 63 (21:88) | 64 (10:89) | 64 (10:89) | MW: p=0.450 |
μ ±DS | 61.65 ±15.9 | 63.40 ±13.8 | 62.94 ±14.4 | ||
Sectie | CHIRURGIE GENERALA I | 0 | 11 (5.8%) | 11 (4.3%) | V=0.32 (p<0.001) |
CHIRURGIE GENERALA II | 3 (4.5%) | 14 (7.4%) | 17 (6.6%) | ||
CHIRURGIE GENERALA III | 3 (4.5%) | 6 (3.2%) | 9 (3.5%) | ||
GASTROENTEROLOGIE I | 6 (9.1%) | 36 (18.9%) | 42 (16.4%) | ||
GASTROENTEROLOGIE II | 13 (19.7%) | 36 (18.9%) | 49 (19.1%) | ||
GASTROENTEROLOGIE III | 33 (50.0%) | 40 (21.1%) | 73 (28.5%) | ||
GASTROENTEROLOGIE IV | 8 (12.1%) | 47 (24.7%) | 55 (21.5%) | ||
Durata internarii | M (min:max) | 9.5 (1:40) | 14 (1:387) | 12 (1:387) | MW: p=0.001 |
μ ±DS | 11.48 ±8.41 | 26.29 ±53.7 | 22.47 ±46.8 | ||
Scor Q | M (min:max) | -1 (-2:0) | 1 (1:3) | 1 (-2:3) | MW: p<0.001 |
μ ±DS | -0.861 ±0.812 | 1.50 ±0.656 | 0.905 ±1.24 | ||
μ ±DS = Media (deviația standard); M (min:max) = Mediana (min:max); MW = Test Mann-Whitney; OR = odds-ratio [cu IC 95%] și p calculat prin testul Fisher); V = Cramér V (p calculat prin testul Chi²); | |||||
Variabila | Detalii | nu | da | Total | Teste statistice |
Scor Q 1-3 | 79 (25.1%) | 236 (74.9%) | 315 | ||
Frotiu: PMN | <10 PMN | 61 (79.2%) | 14 (6.3%) | 75 (25.2%) | V=0.74 (p<0.001) |
>25 PMN | 6 (7.8%) | 145 (65.6%) | 151 (50.7%) | ||
10-25 PMN | 10 (13.0%) | 62 (28.1%) | 72 (24.2%) | ||
Frotiu: CES | <10 CES | 0 | 22 (10.1%) | 22 (7.5%) | V=0.47 (p<0.001) |
10-25 CES | 7 (9.0%) | 113 (52.1%) | 120 (40.7%) | ||
>25 CES | 71 (91.0%) | 82 (37.8%) | 153 (51.9%) | ||
Frotiu: contaminare | contaminare cu saliva flora bacteriana mixta | 2 (2.5%) | 9 (3.8%) | 11 (3.5%) | V=0.21 (p=0.008) |
contaminare cu saliva flora bacteriana polimorfa | 26 (32.9%) | 51 (21.6%) | 77 (24.4%) | ||
contamina cu saliva flora bacteriana redusa | 1 (1.3%) | 0 | 1 (0.3%) | ||
contaminare cu saliva | 4 (5.1%) | 2 (0.8%) | 6 (1.9%) | ||
nu | 46 (58.2%) | 174 (73.7%) | 220 (69.8%) | ||
μ ±DS = Media (deviația standard); M (min:max) = Mediana (min:max); MW = Test Mann-Whitney; OR = odds-ratio [cu IC 95%] și p calculat prin testul Fisher); V = Cramér V (p calculat prin testul Chi²); | |||||
Variabila | Detalii | nu | da | Total | Teste statistice |
Scor Q 1-3 | 79 (25.1%) | 236 (74.9%) | 315 | ||
Rezultat cultura | contaminare | 12 (15.4%) | 0 | 12 (3.8%) | V=0.76 (p<0.001) |
multiplu pozitiv | 0 | 102 (43.2%) | 102 (32.5%) | ||
negativ | 65 (83.3%) | 37 (15.7%) | 102 (32.5%) | ||
pozitiv | 1 (1.3%) | 97 (41.1%) | 98 (31.2%) | ||
Tulpina | Acinetobacter baumannii | 1 (100%) | 22 (12.6%) | 23 (13.1%) | V=0.19 (p>0.999) |
Acinetobacter lwoffii | 0 | 2 (1.1%) | 2 (1.1%) | ||
Burkholderia cepacia | 0 | 2 (1.1%) | 2 (1.1%) | ||
Corynebacterium spp | 0 | 3 (1.7%) | 3 (1.7%) | ||
Enterobacter spp | 0 | 7 (4.0%) | 7 (4.0%) | ||
Enterococcus faecalis | 0 | 2 (1.1%) | 2 (1.1%) | ||
Enterococcus faecium | 0 | 2 (1.1%) | 2 (1.1%) | ||
Enterococcus spp | 0 | 2 (1.1%) | 2 (1.1%) | ||
Escherichia coli | 0 | 14 (8.0%) | 14 (8.0%) | ||
Haemophilus influenzae | 0 | 12 (6.9%) | 12 (6.9%) | ||
Haemophilus parainfluenzae | 0 | 5 (2.9%) | 5 (2.9%) | ||
Haemophilus spp | 0 | 3 (1.7%) | 3 (1.7%) | ||
Klebsiella spp | 0 | 36 (20.7%) | 36 (20.6%) | ||
Moraxella spp | 0 | 4 (2.3%) | 4 (2.3%) | ||
Morganella spp | 0 | 1 (0.6%) | 1 (0.6%) | ||
Pasteurella spp | 0 | 1 (0.6%) | 1 (0.6%) | ||
Proteus vulgaris | 0 | 2 (1.1%) | 2 (1.1%) | ||
Pseudomonas aeruginosa | 0 | 21 (12.1%) | 21 (12.0%) | ||
Pseudomonas fluorescens | 0 | 5 (2.9%) | 5 (2.9%) | ||
Serratia spp | 0 | 5 (2.9%) | 5 (2.9%) | ||
Staphylococcus aureus | 0 | 16 (9.2%) | 16 (9.1%) | ||
Staphylococcus epidermidis | 0 | 2 (1.1%) | 2 (1.1%) | ||
Stenotrophomonas maltophilia | 0 | 5 (2.9%) | 5 (2.9%) | ||
Streptococcus pneumoniae | 0 | 0 | 0 | ||
μ ±DS = Media (deviația standard); M (min:max) = Mediana (min:max); MW = Test Mann-Whitney; OR = odds-ratio [cu IC 95%] și p calculat prin testul Fisher); V = Cramér V (p calculat prin testul Chi²); | |||||
Table: Toate variabilele, in functie de Rezultat cultura
Variabila | Detalii | contaminare | multiplu pozitiv | negativ | pozitiv | Total | Teste statistice |
Rezultat cultura | 12 (3.8%) | 102 (32.5%) | 102 (32.5%) | 98 (31.2%) | 314 | ||
Sursa datelor | Ambulator | 12 (100%) | 19 (18.6%) | 3 (2.9%) | 11 (11.2%) | 45 (14.3%) | V=0.52 (p<0.001) |
Spital | 0 | 83 (81.4%) | 99 (97.1%) | 87 (88.8%) | 269 (85.7%) | ||
Sex | F | 7 (58.3%) | 22 (22.0%) | 43 (42.2%) | 34 (40.0%) | 106 (35.5%) | V=0.21 (p=0.004) |
M | 5 (41.7%) | 78 (78.0%) | 59 (57.8%) | 51 (60.0%) | 193 (64.5%) | ||
Varsta | M (min:max) | 65.5 (40:81) | 63 (10:89) | 63 (21:88) | 65.5 (20:86) | 64 (10:89) | |
μ ±DS | 64.08 ±12.0 | 63.51 ±12.3 | 62.18 ±16.1 | 62.83 ±15.0 | 62.94 ±14.4 | ||
Sectie | CHIRURGIE GENERALA I | 0 (NA) | 3 (3.7%) | 1 (1.0%) | 7 (9.2%) | 11 (4.3%) | V=0.27 (p<0.001) |
CHIRURGIE GENERALA II | 0 (NA) | 9 (11.1%) | 5 (5.1%) | 3 (3.9%) | 17 (6.6%) | ||
CHIRURGIE GENERALA III | 0 (NA) | 2 (2.5%) | 4 (4.0%) | 3 (3.9%) | 9 (3.5%) | ||
GASTROENTEROLOGIE I | 0 (NA) | 11 (13.6%) | 10 (10.1%) | 21 (27.6%) | 42 (16.4%) | ||
GASTROENTEROLOGIE II | 0 (NA) | 18 (22.2%) | 18 (18.2%) | 13 (17.1%) | 49 (19.1%) | ||
GASTROENTEROLOGIE III | 0 (NA) | 19 (23.5%) | 44 (44.4%) | 10 (13.2%) | 73 (28.5%) | ||
GASTROENTEROLOGIE IV | 0 (NA) | 19 (23.5%) | 17 (17.2%) | 19 (25.0%) | 55 (21.5%) | ||
Durata internarii | M (min:max) | 16 (1:366) | 9 (1:387) | 17 (2:97) | 12 (1:387) | ||
μ ±DS | 31.12 ±68.2 | 15.54 ±39.4 | 22.29 ±18.3 | 22.47 ±46.8 | |||
Scor Q | M (min:max) | -1.5 (-2:0) | 2 (1:3) | 0 (-2:3) | 1 (-2:3) | 1 (-2:3) | |
μ ±DS | -1.25 ±0.866 | 1.61 ±0.632 | -0.0392 ±1.21 | 1.43 ±0.786 | 0.905 ±1.24 | ||
Scor Q 1-3 | 0 | 102 (100%) | 37 (36.3%) | 97 (99.0%) | 236 (75.2%) | V=0.76 (p<0.001) | |
μ ±DS = Media (deviația standard); M (min:max) = Mediana (min:max); MW = Test Mann-Whitney; OR = odds-ratio [cu IC 95%] și p calculat prin testul Fisher); V = Cramér V (p calculat prin testul Chi²); | |||||||
Variabila | Detalii | contaminare | multiplu pozitiv | negativ | pozitiv | Total | Teste statistice |
Rezultat cultura | 12 (3.8%) | 102 (32.5%) | 102 (32.5%) | 98 (31.2%) | 314 | ||
Frotiu: PMN | <10 PMN | 8 (66.7%) | 7 (7.0%) | 55 (54.5%) | 5 (5.9%) | 75 (25.2%) | V=0.42 (p<0.001) |
>25 PMN | 2 (16.7%) | 75 (75.0%) | 22 (21.8%) | 52 (61.2%) | 151 (50.7%) | ||
10-25 PMN | 2 (16.7%) | 18 (18.0%) | 24 (23.8%) | 28 (32.9%) | 72 (24.2%) | ||
Frotiu: CES | <10 CES | 0 | 8 (8.2%) | 1 (1.0%) | 13 (15.5%) | 22 (7.5%) | V=0.27 (p<0.001) |
10-25 CES | 2 (16.7%) | 57 (58.8%) | 29 (28.4%) | 32 (38.1%) | 120 (40.7%) | ||
>25 CES | 10 (83.3%) | 32 (33.0%) | 72 (70.6%) | 39 (46.4%) | 153 (51.9%) | ||
Frotiu: contaminare | contaminare cu saliva flora bacteriana mixta | 0 | 1 (1.0%) | 5 (4.9%) | 5 (5.1%) | 11 (3.5%) | V=0.13 (p=0.248) |
contaminare cu saliva flora bacteriana polimorfa | 2 (16.7%) | 23 (22.5%) | 31 (30.4%) | 20 (20.4%) | 76 (24.2%) | ||
contamina cu saliva flora bacteriana redusa | 0 | 0 | 1 (1.0%) | 0 | 1 (0.3%) | ||
contaminare cu saliva | 0 | 2 (2.0%) | 4 (3.9%) | 0 | 6 (1.9%) | ||
nu | 10 (83.3%) | 76 (74.5%) | 61 (59.8%) | 73 (74.5%) | 220 (70.1%) | ||
μ ±DS = Media (deviația standard); M (min:max) = Mediana (min:max); MW = Test Mann-Whitney; OR = odds-ratio [cu IC 95%] și p calculat prin testul Fisher); V = Cramér V (p calculat prin testul Chi²); | |||||||
Variabila | Detalii | contaminare | multiplu pozitiv | negativ | pozitiv | Total | Teste statistice |
Rezultat cultura | 12 (3.8%) | 102 (32.5%) | 102 (32.5%) | 98 (31.2%) | 314 | ||
Tulpina | Acinetobacter baumannii | 0 (NA) | 11 (11.6%) | 0 (NA) | 12 (15.0%) | 23 (13.1%) | V=0.41 (p=0.122) |
Acinetobacter lwoffii | 0 (NA) | 1 (1.1%) | 0 (NA) | 1 (1.2%) | 2 (1.1%) | ||
Burkholderia cepacia | 0 (NA) | 0 | 0 (NA) | 2 (2.5%) | 2 (1.1%) | ||
Corynebacterium spp | 0 (NA) | 2 (2.1%) | 0 (NA) | 1 (1.2%) | 3 (1.7%) | ||
Enterobacter spp | 0 (NA) | 3 (3.2%) | 0 (NA) | 4 (5.0%) | 7 (4.0%) | ||
Enterococcus faecalis | 0 (NA) | 1 (1.1%) | 0 (NA) | 1 (1.2%) | 2 (1.1%) | ||
Enterococcus faecium | 0 (NA) | 1 (1.1%) | 0 (NA) | 1 (1.2%) | 2 (1.1%) | ||
Enterococcus spp | 0 (NA) | 0 | 0 (NA) | 2 (2.5%) | 2 (1.1%) | ||
Escherichia coli | 0 (NA) | 7 (7.4%) | 0 (NA) | 7 (8.7%) | 14 (8.0%) | ||
Haemophilus influenzae | 0 (NA) | 6 (6.3%) | 0 (NA) | 6 (7.5%) | 12 (6.9%) | ||
Haemophilus parainfluenzae | 0 (NA) | 2 (2.1%) | 0 (NA) | 3 (3.8%) | 5 (2.9%) | ||
Haemophilus spp | 0 (NA) | 0 | 0 (NA) | 3 (3.8%) | 3 (1.7%) | ||
Klebsiella spp | 0 (NA) | 26 (27.4%) | 0 (NA) | 10 (12.5%) | 36 (20.6%) | ||
Moraxella spp | 0 (NA) | 0 | 0 (NA) | 4 (5.0%) | 4 (2.3%) | ||
Morganella spp | 0 (NA) | 0 | 0 (NA) | 1 (1.2%) | 1 (0.6%) | ||
Pasteurella spp | 0 (NA) | 1 (1.1%) | 0 (NA) | 0 | 1 (0.6%) | ||
Proteus vulgaris | 0 (NA) | 2 (2.1%) | 0 (NA) | 0 | 2 (1.1%) | ||
Pseudomonas aeruginosa | 0 (NA) | 9 (9.5%) | 0 (NA) | 12 (15.0%) | 21 (12.0%) | ||
Pseudomonas fluorescens | 0 (NA) | 5 (5.3%) | 0 (NA) | 0 | 5 (2.9%) | ||
Serratia spp | 0 (NA) | 3 (3.2%) | 0 (NA) | 2 (2.5%) | 5 (2.9%) | ||
Staphylococcus aureus | 0 (NA) | 11 (11.6%) | 0 (NA) | 5 (6.2%) | 16 (9.1%) | ||
Staphylococcus epidermidis | 0 (NA) | 1 (1.1%) | 0 (NA) | 1 (1.2%) | 2 (1.1%) | ||
Stenotrophomonas maltophilia | 0 (NA) | 3 (3.2%) | 0 (NA) | 2 (2.5%) | 5 (2.9%) | ||
Streptococcus pneumoniae | 0 (NA) | 0 | 0 (NA) | 0 | 0 | ||
μ ±DS = Media (deviația standard); M (min:max) = Mediana (min:max); MW = Test Mann-Whitney; OR = odds-ratio [cu IC 95%] și p calculat prin testul Fisher); V = Cramér V (p calculat prin testul Chi²); | |||||||
Variabila | Detalii | contaminare | multiplu pozitiv | negativ | pozitiv | Total | Teste statistice |
Rezultat cultura | 12 (3.8%) | 102 (32.5%) | 102 (32.5%) | 98 (31.2%) | 314 | ||
Ampicilina | R | 0 (NA) | 30 (68.2%) | 0 (NA) | 24 (53.3%) | 54 (60.7%) | V=0.15 (p=0.347) |
I | 0 (NA) | 1 (2.3%) | 0 (NA) | 2 (4.4%) | 3 (3.4%) | ||
S | 0 (NA) | 13 (29.5%) | 0 (NA) | 19 (42.2%) | 32 (36.0%) | ||
Amoxicilina / acid clavulanic | R | 0 (NA) | 19 (42.2%) | 0 (NA) | 16 (51.6%) | 35 (46.1%) | V=0.09 (p=0.420) |
I | 0 (NA) | 0 | 0 (NA) | 0 | 0 | ||
S | 0 (NA) | 26 (57.8%) | 0 (NA) | 15 (48.4%) | 41 (53.9%) | ||
Piperacilina / tazobactam | R | 0 (NA) | 13 (27.1%) | 0 (NA) | 9 (26.5%) | 22 (26.8%) | V=0.04 (p=0.939) |
I | 0 (NA) | 2 (4.2%) | 0 (NA) | 2 (5.9%) | 4 (4.9%) | ||
S | 0 (NA) | 33 (68.8%) | 0 (NA) | 23 (67.6%) | 56 (68.3%) | ||
Ticarcilina / acid clavulanic | R | 0 (NA) | 9 (64.3%) | 0 (NA) | 6 (54.5%) | 15 (60.0%) | V=0.23 (p=0.504) |
I | 0 (NA) | 1 (7.1%) | 0 (NA) | 0 | 1 (4.0%) | ||
S | 0 (NA) | 4 (28.6%) | 0 (NA) | 5 (45.5%) | 9 (36.0%) | ||
Cefazolina | R | 0 (NA) | 4 (26.7%) | 0 (NA) | 4 (30.8%) | 8 (28.6%) | V=0.18 (p=0.633) |
I | 0 (NA) | 1 (6.7%) | 0 (NA) | 0 | 1 (3.6%) | ||
S | 0 (NA) | 10 (66.7%) | 0 (NA) | 9 (69.2%) | 19 (67.9%) | ||
Cefalexin | R | 0 (NA) | 6 (75.0%) | 0 (NA) | 6 (100%) | 12 (85.7%) | V=0.35 (p=0.186) |
I | 0 (NA) | 0 | 0 (NA) | 0 | 0 | ||
S | 0 (NA) | 2 (25.0%) | 0 (NA) | 0 | 2 (14.3%) | ||
Cefoxitin | R | 0 (NA) | 11 (42.3%) | 0 (NA) | 12 (48.0%) | 23 (45.1%) | V=0.06 (p=0.683) |
I | 0 (NA) | 0 | 0 (NA) | 0 | 0 | ||
S | 0 (NA) | 15 (57.7%) | 0 (NA) | 13 (52.0%) | 28 (54.9%) | ||
Cefuroxim | R | 0 (NA) | 12 (33.3%) | 0 (NA) | 12 (42.9%) | 24 (37.5%) | V=0.10 (p=0.435) |
I | 0 (NA) | 0 | 0 (NA) | 0 | 0 | ||
S | 0 (NA) | 24 (66.7%) | 0 (NA) | 16 (57.1%) | 40 (62.5%) | ||
Cefotaxim | R | 0 (NA) | 6 (15.0%) | 0 (NA) | 9 (23.7%) | 15 (19.2%) | V=0.24 (p=0.099) |
I | 0 (NA) | 0 | 0 (NA) | 3 (7.9%) | 3 (3.8%) | ||
S | 0 (NA) | 34 (85.0%) | 0 (NA) | 26 (68.4%) | 60 (76.9%) | ||
Ceftazidim | R | 0 (NA) | 8 (14.0%) | 0 (NA) | 13 (31.0%) | 21 (21.2%) | V=0.20 (p=0.042) |
I | 0 (NA) | 0 | 0 (NA) | 0 | 0 | ||
S | 0 (NA) | 49 (86.0%) | 0 (NA) | 29 (69.0%) | 78 (78.8%) | ||
Cefoperazona / sulbactam | R | 0 (NA) | 8 (100%) | 0 (NA) | 10 (90.9%) | 18 (94.7%) | V=0.20 (p=0.381) |
I | 0 (NA) | 0 | 0 (NA) | 0 | 0 | ||
S | 0 (NA) | 0 | 0 (NA) | 1 (9.1%) | 1 (5.3%) | ||
Ceftriaxona | R | 0 (NA) | 7 (20.0%) | 0 (NA) | 9 (28.1%) | 16 (23.9%) | V=0.26 (p=0.108) |
I | 0 (NA) | 0 | 0 (NA) | 3 (9.4%) | 3 (4.5%) | ||
S | 0 (NA) | 28 (80.0%) | 0 (NA) | 20 (62.5%) | 48 (71.6%) | ||
Cefoperazona | R | 0 (NA) | 13 (100%) | 0 (NA) | 12 (80.0%) | 25 (89.3%) | V=0.32 (p=0.088) |
I | 0 (NA) | 0 | 0 (NA) | 0 | 0 | ||
S | 0 (NA) | 0 | 0 (NA) | 3 (20.0%) | 3 (10.7%) | ||
Cefepim | R | 0 (NA) | 6 (18.8%) | 0 (NA) | 11 (42.3%) | 17 (29.3%) | V=0.26 (p=0.050) |
I | 0 (NA) | 0 | 0 (NA) | 0 | 0 | ||
S | 0 (NA) | 26 (81.2%) | 0 (NA) | 15 (57.7%) | 41 (70.7%) | ||
Ertapenem | R | 0 (NA) | 2 (8.7%) | 0 (NA) | 3 (25.0%) | 5 (14.3%) | V=0.25 (p=0.346) |
I | 0 (NA) | 1 (4.3%) | 0 (NA) | 0 | 1 (2.9%) | ||
S | 0 (NA) | 20 (87.0%) | 0 (NA) | 9 (75.0%) | 29 (82.9%) | ||
Imipenem | R | 0 (NA) | 11 (17.5%) | 0 (NA) | 12 (21.4%) | 23 (19.3%) | V=0.09 (p=0.599) |
I | 0 (NA) | 3 (4.8%) | 0 (NA) | 1 (1.8%) | 4 (3.4%) | ||
S | 0 (NA) | 49 (77.8%) | 0 (NA) | 43 (76.8%) | 92 (77.3%) | ||
Meropenem | R | 0 (NA) | 15 (22.7%) | 0 (NA) | 17 (28.3%) | 32 (25.4%) | V=0.18 (p=0.134) |
I | 0 (NA) | 4 (6.1%) | 0 (NA) | 0 | 4 (3.2%) | ||
S | 0 (NA) | 47 (71.2%) | 0 (NA) | 43 (71.7%) | 90 (71.4%) | ||
Aztreonam | R | 0 (NA) | 3 (20.0%) | 0 (NA) | 4 (26.7%) | 7 (23.3%) | V=0.14 (p=0.753) |
I | 0 (NA) | 5 (33.3%) | 0 (NA) | 6 (40.0%) | 11 (36.7%) | ||
S | 0 (NA) | 7 (46.7%) | 0 (NA) | 5 (33.3%) | 12 (40.0%) | ||
Benzilpenicilina | R | 0 (NA) | 12 (80.0%) | 0 (NA) | 7 (58.3%) | 19 (70.4%) | V=0.58 (p=0.011) |
I | 0 (NA) | 0 | 0 (NA) | 5 (41.7%) | 5 (18.5%) | ||
S | 0 (NA) | 3 (20.0%) | 0 (NA) | 0 | 3 (11.1%) | ||
Ampicilina / sulbactam | R | 0 (NA) | 5 (62.5%) | 0 (NA) | 4 (50.0%) | 9 (56.2%) | V=0.13 (p=0.614) |
I | 0 (NA) | 0 | 0 (NA) | 0 | 0 | ||
S | 0 (NA) | 3 (37.5%) | 0 (NA) | 4 (50.0%) | 7 (43.8%) | ||
Oxacilina | R | 0 (NA) | 6 (37.5%) | 0 (NA) | 3 (50.0%) | 9 (40.9%) | V=0.11 (p=0.595) |
I | 0 (NA) | 0 | 0 (NA) | 0 | 0 | ||
S | 0 (NA) | 10 (62.5%) | 0 (NA) | 3 (50.0%) | 13 (59.1%) | ||
Piperacilina | R | 0 (NA) | 3 (18.8%) | 0 (NA) | 9 (50.0%) | 12 (35.3%) | V=0.39 (p=0.078) |
I | 0 (NA) | 2 (12.5%) | 0 (NA) | 0 | 2 (5.9%) | ||
S | 0 (NA) | 11 (68.8%) | 0 (NA) | 9 (50.0%) | 20 (58.8%) | ||
Penicilina | R | 0 (NA) | 1 (50.0%) | 0 (NA) | 1 (100%) | 2 (66.7%) | V=0.50 (p=0.386) |
I | 0 (NA) | 0 | 0 (NA) | 0 | 0 | ||
S | 0 (NA) | 1 (50.0%) | 0 (NA) | 0 | 1 (33.3%) | ||
Ciprofloxacina | R | 0 (NA) | 18 (21.2%) | 0 (NA) | 21 (30.0%) | 39 (25.2%) | V=0.10 (p=0.441) |
I | 0 (NA) | 1 (1.2%) | 0 (NA) | 1 (1.4%) | 2 (1.3%) | ||
S | 0 (NA) | 66 (77.6%) | 0 (NA) | 48 (68.6%) | 114 (73.5%) | ||
Ofloxacina | R | 0 (NA) | 2 (8.0%) | 0 (NA) | 2 (7.4%) | 4 (7.7%) | V=0.01 (p=0.936) |
I | 0 (NA) | 0 | 0 (NA) | 0 | 0 | ||
S | 0 (NA) | 23 (92.0%) | 0 (NA) | 25 (92.6%) | 48 (92.3%) | ||
Levofloxacina | R | 0 (NA) | 16 (24.2%) | 0 (NA) | 18 (27.7%) | 34 (26.0%) | V=0.04 (p=0.903) |
I | 0 (NA) | 1 (1.5%) | 0 (NA) | 1 (1.5%) | 2 (1.5%) | ||
S | 0 (NA) | 49 (74.2%) | 0 (NA) | 46 (70.8%) | 95 (72.5%) | ||
Moxifloxacina | R | 0 (NA) | 7 (35.0%) | 0 (NA) | 7 (41.2%) | 14 (37.8%) | V=0.16 (p=0.624) |
I | 0 (NA) | 1 (5.0%) | 0 (NA) | 0 | 1 (2.7%) | ||
S | 0 (NA) | 12 (60.0%) | 0 (NA) | 10 (58.8%) | 22 (59.5%) | ||
Norfloxacina | R | 0 (NA) | 13 (48.1%) | 0 (NA) | 8 (66.7%) | 21 (53.8%) | V=0.17 (p=0.284) |
I | 0 (NA) | 0 | 0 (NA) | 0 | 0 | ||
S | 0 (NA) | 14 (51.9%) | 0 (NA) | 4 (33.3%) | 18 (46.2%) | ||
Vancomicina | R | 0 (NA) | 1 (5.0%) | 0 (NA) | 2 (11.8%) | 3 (8.1%) | V=0.12 (p=0.452) |
I | 0 (NA) | 0 | 0 (NA) | 0 | 0 | ||
S | 0 (NA) | 19 (95.0%) | 0 (NA) | 15 (88.2%) | 34 (91.9%) | ||
Teicoplanin | R | 0 (NA) | 1 (9.1%) | 0 (NA) | 2 (14.3%) | 3 (12.0%) | V=0.08 (p=0.692) |
I | 0 (NA) | 0 | 0 (NA) | 0 | 0 | ||
S | 0 (NA) | 10 (90.9%) | 0 (NA) | 12 (85.7%) | 22 (88.0%) | ||
Amikacina | R | 0 (NA) | 4 (9.5%) | 0 (NA) | 12 (34.3%) | 16 (20.8%) | V=0.31 (p=0.023) |
I | 0 (NA) | 3 (7.1%) | 0 (NA) | 3 (8.6%) | 6 (7.8%) | ||
S | 0 (NA) | 35 (83.3%) | 0 (NA) | 20 (57.1%) | 55 (71.4%) | ||
Gentamicina | R | 0 (NA) | 8 (13.1%) | 0 (NA) | 10 (23.8%) | 18 (17.5%) | V=0.14 (p=0.368) |
I | 0 (NA) | 2 (3.3%) | 0 (NA) | 1 (2.4%) | 3 (2.9%) | ||
S | 0 (NA) | 51 (83.6%) | 0 (NA) | 31 (73.8%) | 82 (79.6%) | ||
Tobramicina | R | 0 (NA) | 6 (10.3%) | 0 (NA) | 9 (23.7%) | 15 (15.6%) | V=0.18 (p=0.078) |
I | 0 (NA) | 0 | 0 (NA) | 0 | 0 | ||
S | 0 (NA) | 52 (89.7%) | 0 (NA) | 29 (76.3%) | 81 (84.4%) | ||
Netilmicina | R | 0 (NA) | 2 (14.3%) | 0 (NA) | 1 (33.3%) | 3 (17.6%) | V=0.19 (p=0.432) |
I | 0 (NA) | 0 | 0 (NA) | 0 | 0 | ||
S | 0 (NA) | 12 (85.7%) | 0 (NA) | 2 (66.7%) | 14 (82.4%) | ||
Tetraciclina | R | 0 (NA) | 11 (30.6%) | 0 (NA) | 16 (42.1%) | 27 (36.5%) | V=0.12 (p=0.302) |
I | 0 (NA) | 0 | 0 (NA) | 0 | 0 | ||
S | 0 (NA) | 25 (69.4%) | 0 (NA) | 22 (57.9%) | 47 (63.5%) | ||
Minociclina | R | 0 (NA) | 1 (8.3%) | 0 (NA) | 1 (11.1%) | 2 (9.5%) | V=0.20 (p=0.667) |
I | 0 (NA) | 1 (8.3%) | 0 (NA) | 0 | 1 (4.8%) | ||
S | 0 (NA) | 10 (83.3%) | 0 (NA) | 8 (88.9%) | 18 (85.7%) | ||
Tigeciclina | R | 0 (NA) | 0 | 0 (NA) | 0 | 0 | V=NA (p>0.999) |
I | 0 (NA) | 0 | 0 (NA) | 0 | 0 | ||
S | 0 (NA) | 14 (100%) | 0 (NA) | 8 (100%) | 22 (100%) | ||
Kanamicina | R | 0 (NA) | 2 (66.7%) | 0 (NA) | 0 (NA) | 2 (66.7%) | V=NA (p>0.999) |
I | 0 (NA) | 0 | 0 (NA) | 0 (NA) | 0 | ||
S | 0 (NA) | 1 (33.3%) | 0 (NA) | 0 (NA) | 1 (33.3%) | ||
Eritromicina | R | 0 (NA) | 6 (31.6%) | 0 (NA) | 8 (44.4%) | 14 (37.8%) | V=0.23 (p=0.370) |
I | 0 (NA) | 0 | 0 (NA) | 1 (5.6%) | 1 (2.7%) | ||
S | 0 (NA) | 13 (68.4%) | 0 (NA) | 9 (50.0%) | 22 (59.5%) | ||
Azitromicina | R | 0 (NA) | 3 (20.0%) | 0 (NA) | 3 (16.7%) | 6 (18.2%) | V=0.04 (p=0.805) |
I | 0 (NA) | 0 | 0 (NA) | 0 | 0 | ||
S | 0 (NA) | 12 (80.0%) | 0 (NA) | 15 (83.3%) | 27 (81.8%) | ||
Claritromicina | R | 0 (NA) | 3 (33.3%) | 0 (NA) | 3 (37.5%) | 6 (35.3%) | V=0.04 (p=0.858) |
I | 0 (NA) | 0 | 0 (NA) | 0 | 0 | ||
S | 0 (NA) | 6 (66.7%) | 0 (NA) | 5 (62.5%) | 11 (64.7%) | ||
Clindamicina | R | 0 (NA) | 5 (31.2%) | 0 (NA) | 5 (62.5%) | 10 (41.7%) | V=0.30 (p=0.143) |
I | 0 (NA) | 0 | 0 (NA) | 0 | 0 | ||
S | 0 (NA) | 11 (68.8%) | 0 (NA) | 3 (37.5%) | 14 (58.3%) | ||
Ticarcilina | R | 0 (NA) | 12 (92.3%) | 0 (NA) | 7 (100%) | 19 (95.0%) | V=0.17 (p=0.452) |
I | 0 (NA) | 0 | 0 (NA) | 0 | 0 | ||
S | 0 (NA) | 1 (7.7%) | 0 (NA) | 0 | 1 (5.0%) | ||
Streptomicina | R | 0 (NA) | 1 (100%) | 0 (NA) | 1 (50.0%) | 2 (66.7%) | V=0.50 (p=0.386) |
I | 0 (NA) | 0 | 0 (NA) | 0 | 0 | ||
S | 0 (NA) | 0 | 0 (NA) | 1 (50.0%) | 1 (33.3%) | ||
Quinupristin / dalfopristin | R | 0 (NA) | 2 (100%) | 0 (NA) | 1 (50.0%) | 3 (75.0%) | V=0.58 (p=0.248) |
I | 0 (NA) | 0 | 0 (NA) | 0 | 0 | ||
S | 0 (NA) | 0 | 0 (NA) | 1 (50.0%) | 1 (25.0%) | ||
Fosfomicina | R | 0 (NA) | 2 (10.0%) | 0 (NA) | 2 (16.7%) | 4 (12.5%) | V=0.10 (p=0.581) |
I | 0 (NA) | 0 | 0 (NA) | 0 | 0 | ||
S | 0 (NA) | 18 (90.0%) | 0 (NA) | 10 (83.3%) | 28 (87.5%) | ||
Colistin | R | 0 (NA) | 2 (8.0%) | 0 (NA) | 1 (4.8%) | 3 (6.5%) | V=0.07 (p=0.658) |
I | 0 (NA) | 0 | 0 (NA) | 0 | 0 | ||
S | 0 (NA) | 23 (92.0%) | 0 (NA) | 20 (95.2%) | 43 (93.5%) | ||
Cloramfenicol | R | 0 (NA) | 0 | 0 (NA) | 0 | 0 | V=NA (p>0.999) |
I | 0 (NA) | 0 | 0 (NA) | 0 | 0 | ||
S | 0 (NA) | 26 (100%) | 0 (NA) | 31 (100%) | 57 (100%) | ||
Nitrofurantoin | R | 0 (NA) | 6 (54.5%) | 0 (NA) | 0 | 6 (42.9%) | V=0.45 (p=0.091) |
I | 0 (NA) | 0 | 0 (NA) | 0 | 0 | ||
S | 0 (NA) | 5 (45.5%) | 0 (NA) | 3 (100%) | 8 (57.1%) | ||
Trimetoprim / sulfametoxazol | R | 0 (NA) | 27 (35.1%) | 0 (NA) | 16 (23.5%) | 43 (29.7%) | V=0.13 (p=0.129) |
I | 0 (NA) | 0 | 0 (NA) | 0 | 0 | ||
S | 0 (NA) | 50 (64.9%) | 0 (NA) | 52 (76.5%) | 102 (70.3%) | ||
Linezolid | R | 0 (NA) | 0 | 0 (NA) | 0 | 0 | V=NA (p>0.999) |
I | 0 (NA) | 0 | 0 (NA) | 0 | 0 | ||
S | 0 (NA) | 18 (100%) | 0 (NA) | 16 (100%) | 34 (100%) | ||
Acid fusidic | R | 0 (NA) | 0 | 0 (NA) | 1 (16.7%) | 1 (6.7%) | V=0.33 (p=0.205) |
I | 0 (NA) | 0 | 0 (NA) | 0 | 0 | ||
S | 0 (NA) | 9 (100%) | 0 (NA) | 5 (83.3%) | 14 (93.3%) | ||
Rifampicina | R | 0 (NA) | 3 (25.0%) | 0 (NA) | 1 (11.1%) | 4 (19.0%) | V=0.39 (p=0.198) |
I | 0 (NA) | 0 | 0 (NA) | 2 (22.2%) | 2 (9.5%) | ||
S | 0 (NA) | 9 (75.0%) | 0 (NA) | 6 (66.7%) | 15 (71.4%) | ||
μ ±DS = Media (deviația standard); M (min:max) = Mediana (min:max); MW = Test Mann-Whitney; OR = odds-ratio [cu IC 95%] și p calculat prin testul Fisher); V = Cramér V (p calculat prin testul Chi²); | |||||||
2.3.1 Bacterii
[1] “Acinetobacter baumannii” 
[1] “Acinetobacter lwoffii” 
[1] “Burkholderia cepacia” 
[1] “Corynebacterium spp” 
[1] “Enterobacter spp” 
[1] “Enterococcus faecalis” 
[1] “Enterococcus faecium” 
[1] “Enterococcus spp” 
[1] “Escherichia coli” 
[1] “Haemophilus influenzae” 
[1] “Haemophilus parainfluenzae” 
[1] “Haemophilus spp” 
[1] “Klebsiella spp” 
[1] “Moraxella spp” 
[1] “Morganella spp” 
[1] “Proteus vulgaris” 
[1] “Pseudomonas aeruginosa” 
[1] “Pseudomonas fluorescens” 
[1] “Serratia spp” 
[1] “Staphylococcus aureus” 
[1] “Staphylococcus epidermidis” 
[1] “Stenotrophomonas maltophilia” 
2.3.2 Demografie
2.4 Discuții
2.5 Concluzie
3 Bibliografie
- R Core Team (2020). R: A language and environment for statistical computing. R Foundation for Statistical Computing, Vienna, Austria. URL https://www.R-project.org/.
.