Distribution Of tumors

DIAGNOSIS Distribution
SCHWANNOMA 18 (45 % )
MENINGIOMA 10 (25 % )
EPENDYMOMA 5 (12.5 % )
NEUROFIBROMA 4 (10 % )
NEUROENTERIC CYST 2 (5 % )
EPIDERMOID CYST 1 (2.5 % )

SUMMARY TABLE ALL

Dependent: all all
AGE Mean (SD) 38.8 (12.3)
SEX FEMALE 23 (57.5)
MALE 17 (42.5)
SITE Cervical 4 (10.0)
Lumbar 8 (20.0)
Thoracic 18 (45.0)
Thoraco Lumbar 10 (25.0)
AXIAL Anterior 9 (22.5)
Posterior 19 (47.5)
Posterolateral 12 (30.0)
OCCUPANCY Mean (SD) 80.0 (5.4)
VAS0 4 5 (12.5)
6 24 (60.0)
8 9 (22.5)
10 2 (5.0)
VAS6W 2 10 (25.0)
4 20 (50.0)
6 10 (25.0)
VAS12W 1 3 (7.5)
2 9 (22.5)
3 21 (52.5)
4 7 (17.5)
VAS6M 1 10 (25.0)
2 25 (62.5)
3 1 (2.5)
4 4 (10.0)
FC0 2 6 (15.0)
3 14 (35.0)
4 20 (50.0)
FC6W 2 6 (15.0)
3 7 (17.5)
4 19 (47.5)
5 8 (20.0)
FC12W 2 3 (7.5)
3 5 (12.5)
4 21 (52.5)
5 11 (27.5)
FC6M 2 3 (7.5)
3 5 (12.5)
4 20 (50.0)
5 12 (30.0)
DURATION_OF_SYMPTOM Mean (SD) 9.0 (3.0)
deltavas Mean (SD) 4.4 (1.1)
deltaFC 0 15 (37.5)
1 23 (57.5)
2 2 (5.0)
tumor EPENDYMOMA 5 (12.5)
MENINGIOMA 10 (25.0)
NERVE SHEATH TUMOUR 22 (55.0)
OTHER 3 (7.5)
tumorsa EPENDYMOMA 5 (12.5)
MENINGIOMA 10 (25.0)
NEUROFIBROMA 4 (10.0)
SCHWANNOMA 18 (45.0)
Other 3 (7.5)

SUMMARY TABLE BY TYPE OF TUMOUR

label levels EPENDYMOMA MENINGIOMA NERVE SHEATH TUMOUR OTHER p
AGE Mean (SD) 34.8 (8.3) 44.9 (8.6) 39.3 (13.1) 21.7 (2.3) 0.015
SEX FEMALE 4 (80.0) 5 (50.0) 13 (59.1) 1 (33.3) 0.571
MALE 1 (20.0) 5 (50.0) 9 (40.9) 2 (66.7)
SITE Cervical 0 (0.0) 2 (20.0) 1 (4.5) 1 (33.3) 0.004
Lumbar 4 (80.0) 0 (0.0) 4 (18.2) 0 (0.0)
Thoracic 0 (0.0) 8 (80.0) 9 (40.9) 1 (33.3)
Thoraco Lumbar 1 (20.0) 0 (0.0) 8 (36.4) 1 (33.3)
AXIAL Anterior 1 (20.0) 5 (50.0) 0 (0.0) 3 (100.0) <0.001
Posterior 4 (80.0) 0 (0.0) 15 (68.2) 0 (0.0)
Posterolateral 0 (0.0) 5 (50.0) 7 (31.8) 0 (0.0)
OCCUPANCY Mean (SD) 81.5 (3.6) 79.4 (7.2) 79.6 (4.9) 82.8 (6.4) 0.753
VAS0 4 0 (0.0) 3 (30.0) 2 (9.1) 0 (0.0) 0.485
6 2 (40.0) 6 (60.0) 14 (63.6) 2 (66.7)
8 2 (40.0) 1 (10.0) 5 (22.7) 1 (33.3)
10 1 (20.0) 0 (0.0) 1 (4.5) 0 (0.0)
VAS6W 2 0 (0.0) 4 (40.0) 5 (22.7) 1 (33.3) 0.673
4 3 (60.0) 5 (50.0) 11 (50.0) 1 (33.3)
6 2 (40.0) 1 (10.0) 6 (27.3) 1 (33.3)
VAS12W 1 0 (0.0) 1 (10.0) 2 (9.1) 0 (0.0) 0.897
2 0 (0.0) 3 (30.0) 5 (22.7) 1 (33.3)
3 4 (80.0) 4 (40.0) 12 (54.5) 1 (33.3)
4 1 (20.0) 2 (20.0) 3 (13.6) 1 (33.3)
VAS6M 1 0 (0.0) 5 (50.0) 3 (13.6) 2 (66.7) 0.316
2 4 (80.0) 4 (40.0) 16 (72.7) 1 (33.3)
3 0 (0.0) 0 (0.0) 1 (4.5) 0 (0.0)
4 1 (20.0) 1 (10.0) 2 (9.1) 0 (0.0)
FC0 2 1 (20.0) 2 (20.0) 3 (13.6) 0 (0.0) 0.981
3 2 (40.0) 3 (30.0) 8 (36.4) 1 (33.3)
4 2 (40.0) 5 (50.0) 11 (50.0) 2 (66.7)
FC6W 2 1 (20.0) 2 (20.0) 3 (13.6) 0 (0.0) 0.981
3 1 (20.0) 2 (20.0) 4 (18.2) 0 (0.0)
4 2 (40.0) 5 (50.0) 10 (45.5) 2 (66.7)
5 1 (20.0) 1 (10.0) 5 (22.7) 1 (33.3)
FC12W 2 1 (20.0) 1 (10.0) 1 (4.5) 0 (0.0) 0.799
3 1 (20.0) 2 (20.0) 2 (9.1) 0 (0.0)
4 2 (40.0) 5 (50.0) 13 (59.1) 1 (33.3)
5 1 (20.0) 2 (20.0) 6 (27.3) 2 (66.7)
FC6M 2 1 (20.0) 1 (10.0) 1 (4.5) 0 (0.0) 0.827
3 1 (20.0) 2 (20.0) 2 (9.1) 0 (0.0)
4 2 (40.0) 5 (50.0) 12 (54.5) 1 (33.3)
5 1 (20.0) 2 (20.0) 7 (31.8) 2 (66.7)
DURATION_OF_SYMPTOM Mean (SD) 10.4 (3.7) 9.5 (3.5) 8.7 (2.6) 7.0 (3.3) 0.491
deltavas Mean (SD) 5.2 (1.8) 3.9 (0.7) 4.4 (1.0) 5.3 (0.6) 0.067
deltaFC 0 3 (60.0) 5 (50.0) 7 (31.8) 0 (0.0) 0.499
1 2 (40.0) 5 (50.0) 13 (59.1) 3 (100.0)
2 0 (0.0) 0 (0.0) 2 (9.1) 0 (0.0)

SUMMARY TABLE BY TYPE OF TUMOUR (INDIVIDUAL)

label levels EPENDYMOMA MENINGIOMA NEUROFIBROMA Other SCHWANNOMA p
AGE Mean (SD) 34.8 (8.3) 44.9 (8.6) 30.2 (8.9) 21.7 (2.3) 41.3 (13.2) 0.009
SEX FEMALE 4 (80.0) 5 (50.0) 2 (50.0) 1 (33.3) 11 (61.1) 0.704
MALE 1 (20.0) 5 (50.0) 2 (50.0) 2 (66.7) 7 (38.9)
SITE Cervical 0 (0.0) 2 (20.0) 1 (25.0) 1 (33.3) 0 (0.0) 0.002
Lumbar 4 (80.0) 0 (0.0) 2 (50.0) 0 (0.0) 2 (11.1)
Thoracic 0 (0.0) 8 (80.0) 0 (0.0) 1 (33.3) 9 (50.0)
Thoraco Lumbar 1 (20.0) 0 (0.0) 1 (25.0) 1 (33.3) 7 (38.9)
AXIAL Anterior 1 (20.0) 5 (50.0) 0 (0.0) 3 (100.0) 0 (0.0) <0.001
Posterior 4 (80.0) 0 (0.0) 3 (75.0) 0 (0.0) 12 (66.7)
Posterolateral 0 (0.0) 5 (50.0) 1 (25.0) 0 (0.0) 6 (33.3)
OCCUPANCY Mean (SD) 81.5 (3.6) 79.4 (7.2) 81.0 (4.1) 82.8 (6.4) 79.2 (5.1) 0.840
VAS0 4 0 (0.0) 3 (30.0) 1 (25.0) 0 (0.0) 1 (5.6) 0.405
6 2 (40.0) 6 (60.0) 1 (25.0) 2 (66.7) 13 (72.2)
8 2 (40.0) 1 (10.0) 2 (50.0) 1 (33.3) 3 (16.7)
10 1 (20.0) 0 (0.0) 0 (0.0) 0 (0.0) 1 (5.6)
VAS6W 2 0 (0.0) 4 (40.0) 2 (50.0) 1 (33.3) 3 (16.7) 0.636
4 3 (60.0) 5 (50.0) 1 (25.0) 1 (33.3) 10 (55.6)
6 2 (40.0) 1 (10.0) 1 (25.0) 1 (33.3) 5 (27.8)
VAS12W 1 0 (0.0) 1 (10.0) 1 (25.0) 0 (0.0) 1 (5.6) 0.720
2 0 (0.0) 3 (30.0) 2 (50.0) 1 (33.3) 3 (16.7)
3 4 (80.0) 4 (40.0) 1 (25.0) 1 (33.3) 11 (61.1)
4 1 (20.0) 2 (20.0) 0 (0.0) 1 (33.3) 3 (16.7)
VAS6M 1 0 (0.0) 5 (50.0) 1 (25.0) 2 (66.7) 2 (11.1) 0.486
2 4 (80.0) 4 (40.0) 3 (75.0) 1 (33.3) 13 (72.2)
3 0 (0.0) 0 (0.0) 0 (0.0) 0 (0.0) 1 (5.6)
4 1 (20.0) 1 (10.0) 0 (0.0) 0 (0.0) 2 (11.1)
FC0 2 1 (20.0) 2 (20.0) 0 (0.0) 0 (0.0) 3 (16.7) 0.818
3 2 (40.0) 3 (30.0) 3 (75.0) 1 (33.3) 5 (27.8)
4 2 (40.0) 5 (50.0) 1 (25.0) 2 (66.7) 10 (55.6)
FC6W 2 1 (20.0) 2 (20.0) 0 (0.0) 0 (0.0) 3 (16.7) 0.944
3 1 (20.0) 2 (20.0) 1 (25.0) 0 (0.0) 3 (16.7)
4 2 (40.0) 5 (50.0) 3 (75.0) 2 (66.7) 7 (38.9)
5 1 (20.0) 1 (10.0) 0 (0.0) 1 (33.3) 5 (27.8)
FC12W 2 1 (20.0) 1 (10.0) 0 (0.0) 0 (0.0) 1 (5.6) 0.911
3 1 (20.0) 2 (20.0) 0 (0.0) 0 (0.0) 2 (11.1)
4 2 (40.0) 5 (50.0) 3 (75.0) 1 (33.3) 10 (55.6)
5 1 (20.0) 2 (20.0) 1 (25.0) 2 (66.7) 5 (27.8)
FC6M 2 1 (20.0) 1 (10.0) 0 (0.0) 0 (0.0) 1 (5.6) 0.915
3 1 (20.0) 2 (20.0) 0 (0.0) 0 (0.0) 2 (11.1)
4 2 (40.0) 5 (50.0) 3 (75.0) 1 (33.3) 9 (50.0)
5 1 (20.0) 2 (20.0) 1 (25.0) 2 (66.7) 6 (33.3)
DURATION_OF_SYMPTOM Mean (SD) 10.4 (3.7) 9.5 (3.5) 10.3 (2.8) 7.0 (3.3) 8.4 (2.4) 0.360
deltavas Mean (SD) 5.2 (1.8) 3.9 (0.7) 4.8 (1.9) 5.3 (0.6) 4.3 (0.8) 0.073
deltaFC 0 3 (60.0) 5 (50.0) 0 (0.0) 0 (0.0) 7 (38.9) 0.350
1 2 (40.0) 5 (50.0) 4 (100.0) 3 (100.0) 9 (50.0)
2 0 (0.0) 0 (0.0) 0 (0.0) 0 (0.0) 2 (11.1)
tumor EPENDYMOMA 5 (100.0) 0 (0.0) 0 (0.0) 0 (0.0) 0 (0.0) <0.001
MENINGIOMA 0 (0.0) 10 (100.0) 0 (0.0) 0 (0.0) 0 (0.0)
NERVE SHEATH TUMOUR 0 (0.0) 0 (0.0) 4 (100.0) 0 (0.0) 18 (100.0)
OTHER 0 (0.0) 0 (0.0) 0 (0.0) 3 (100.0) 0 (0.0)

SUMMARY TABLE BY LOCATION

label levels Cervical Lumbar Thoracic Thoraco Lumbar p
AGE Mean (SD) 35.0 (17.9) 36.6 (9.0) 40.4 (11.3) 39.1 (15.1) 0.830
SEX FEMALE 1 (25.0) 5 (62.5) 10 (55.6) 7 (70.0) 0.479
MALE 3 (75.0) 3 (37.5) 8 (44.4) 3 (30.0)
AXIAL Anterior 2 (50.0) 0 (0.0) 5 (27.8) 2 (20.0) 0.475
Posterior 1 (25.0) 6 (75.0) 7 (38.9) 5 (50.0)
Posterolateral 1 (25.0) 2 (25.0) 6 (33.3) 3 (30.0)
OCCUPANCY Mean (SD) 81.2 (7.7) 80.8 (3.0) 78.8 (6.0) 81.0 (5.1) 0.728
VAS0 4 1 (25.0) 1 (12.5) 3 (16.7) 0 (0.0) 0.567
6 3 (75.0) 3 (37.5) 12 (66.7) 6 (60.0)
8 0 (0.0) 3 (37.5) 3 (16.7) 3 (30.0)
10 0 (0.0) 1 (12.5) 0 (0.0) 1 (10.0)
VAS6W 2 2 (50.0) 2 (25.0) 5 (27.8) 1 (10.0) 0.516
4 2 (50.0) 3 (37.5) 10 (55.6) 5 (50.0)
6 0 (0.0) 3 (37.5) 3 (16.7) 4 (40.0)
VAS12W 1 1 (25.0) 0 (0.0) 2 (11.1) 0 (0.0) 0.735
2 1 (25.0) 2 (25.0) 3 (16.7) 3 (30.0)
3 2 (50.0) 5 (62.5) 10 (55.6) 4 (40.0)
4 0 (0.0) 1 (12.5) 3 (16.7) 3 (30.0)
VAS6M 1 3 (75.0) 0 (0.0) 6 (33.3) 1 (10.0) 0.194
2 1 (25.0) 7 (87.5) 10 (55.6) 7 (70.0)
3 0 (0.0) 0 (0.0) 1 (5.6) 0 (0.0)
4 0 (0.0) 1 (12.5) 1 (5.6) 2 (20.0)
FC0 2 2 (50.0) 1 (12.5) 1 (5.6) 2 (20.0) 0.435
3 1 (25.0) 3 (37.5) 6 (33.3) 4 (40.0)
4 1 (25.0) 4 (50.0) 11 (61.1) 4 (40.0)
FC6W 2 2 (50.0) 1 (12.5) 1 (5.6) 2 (20.0) 0.610
3 0 (0.0) 2 (25.0) 3 (16.7) 2 (20.0)
4 2 (50.0) 4 (50.0) 9 (50.0) 4 (40.0)
5 0 (0.0) 1 (12.5) 5 (27.8) 2 (20.0)
FC12W 2 1 (25.0) 1 (12.5) 0 (0.0) 1 (10.0) 0.711
3 1 (25.0) 1 (12.5) 1 (5.6) 2 (20.0)
4 1 (25.0) 4 (50.0) 11 (61.1) 5 (50.0)
5 1 (25.0) 2 (25.0) 6 (33.3) 2 (20.0)
FC6M 2 1 (25.0) 1 (12.5) 0 (0.0) 1 (10.0) 0.689
3 1 (25.0) 1 (12.5) 1 (5.6) 2 (20.0)
4 1 (25.0) 4 (50.0) 10 (55.6) 5 (50.0)
5 1 (25.0) 2 (25.0) 7 (38.9) 2 (20.0)
DURATION_OF_SYMPTOM Mean (SD) 9.6 (3.2) 9.7 (3.0) 8.7 (2.7) 8.8 (3.7) 0.924
deltavas Mean (SD) 4.2 (1.0) 4.8 (1.8) 4.2 (0.8) 4.7 (0.9) 0.615
deltaFC 0 1 (25.0) 4 (50.0) 6 (33.3) 4 (40.0) 0.763
1 3 (75.0) 4 (50.0) 10 (55.6) 6 (60.0)
2 0 (0.0) 0 (0.0) 2 (11.1) 0 (0.0)
tumor EPENDYMOMA 0 (0.0) 4 (50.0) 0 (0.0) 1 (10.0) 0.004
MENINGIOMA 2 (50.0) 0 (0.0) 8 (44.4) 0 (0.0)
NERVE SHEATH TUMOUR 1 (25.0) 4 (50.0) 9 (50.0) 8 (80.0)
OTHER 1 (25.0) 0 (0.0) 1 (5.6) 1 (10.0)
tumorsa EPENDYMOMA 0 (0.0) 4 (50.0) 0 (0.0) 1 (10.0) 0.002
MENINGIOMA 2 (50.0) 0 (0.0) 8 (44.4) 0 (0.0)
NEUROFIBROMA 1 (25.0) 2 (25.0) 0 (0.0) 1 (10.0)
SCHWANNOMA 0 (0.0) 2 (25.0) 9 (50.0) 7 (70.0)
Other 1 (25.0) 0 (0.0) 1 (5.6) 1 (10.0)

Gender Distribution

The Flipped Bar- plot above shows Counts(X axis) and percentages(annotated within bar) of various categories. The top 2 sub-groups are as follows : 23/40(57.5 %) patients are in sub-group FEMALE 17/40(42.5 %) patients are in sub-group MALE The Full details of distribution is in table below.

Group n total percentage Confidence_Interval
FEMALE 23 40 57.5 42.1% - 71.85%
MALE 17 40 42.5 28.15% - 57.9%

AGE DISTRIBUTION

we found a Significant association between age_grp and tumor frequency. The chi-square statistic was 34.56 . The degree of freedom was 18 and P value was 0.01 .Contingency and Proportion table are shown below

EPENDYMOMA MENINGIOMA NEUROFIBROMA SCHWANNOMA Other
10-20 0 0 0 0 1
20-30 2 0 2 4 2
30-40 1 4 1 6 0
40-50 2 3 1 3 0
50-60 0 3 0 3 0
60-70 0 0 0 2 0
tumorsa age_grp n value 95 % Confidence Interval
EPENDYMOMA 20-30 2 2/5 ( 40 %) 9.44% - 79.06%
EPENDYMOMA 30-40 1 1/5 ( 20 %) 2.25% - 62.86%
EPENDYMOMA 40-50 2 2/5 ( 40 %) 9.44% - 79.06%
MENINGIOMA 30-40 4 4/10 ( 40 %) 15.31% - 69.63%
MENINGIOMA 40-50 3 3/10 ( 30 %) 9.27% - 60.58%
MENINGIOMA 50-60 3 3/10 ( 30 %) 9.27% - 60.58%
NEUROFIBROMA 20-30 2 2/4 ( 50 %) 12.28% - 87.72%
NEUROFIBROMA 30-40 1 1/4 ( 25 %) 2.85% - 71.62%
NEUROFIBROMA 40-50 1 1/4 ( 25 %) 2.85% - 71.62%
SCHWANNOMA 20-30 4 4/18 ( 22.22 %) 8% - 44.58%
SCHWANNOMA 30-40 6 6/18 ( 33.33 %) 15.28% - 56.28%
SCHWANNOMA 40-50 3 3/18 ( 16.67 %) 4.93% - 38.14%
SCHWANNOMA 50-60 3 3/18 ( 16.67 %) 4.93% - 38.14%
SCHWANNOMA 60-70 2 2/18 ( 11.11 %) 2.38% - 31.12%
Other 10-20 1 1/3 ( 33.33 %) 3.87% - 82.33%
Other 20-30 2 2/3 ( 66.67 %) 17.67% - 96.13%

DURATION OF SYMPTOMS

SITE <6 >6
Cervical NA 4
Lumbar NA 8
Thoracic 3 15
Thoraco Lumbar 3 7

PRE-OP FRENKEL SCORES

SITE 2 3 4
Cervical 2 1 1
Lumbar 1 3 4
Thoracic 1 6 11
Thoraco Lumbar 2 4 4
DIAGNOSIS 2 3 4
EPENDYMOMA 1 2 2
EPIDERMOID CYST 1
MENINGIOMA 2 3 5
NEUROENTERIC CYST 1 1
NEUROFIBROMA 3 1
SCHWANNOMA 3 5 10

PREOP_PAIN - VISUAL ANALOG SCALE

DIAGNOSIS 4 6 8 10
EPENDYMOMA 2 2 1
EPIDERMOID CYST 1
MENINGIOMA 3 6 1
NEUROENTERIC CYST 2
NEUROFIBROMA 1 1 2
SCHWANNOMA 1 13 3 1
SITE 4 6 8 10
Cervical 1 3
Lumbar 1 3 3 1
Thoracic 3 12 3
Thoraco Lumbar 6 3 1

DISTRIBUTION OF TUMOUR SITE

DIAGNOSIS Cervical Lumbar Thoracic Thoraco Lumbar
EPENDYMOMA 4 1
EPIDERMOID CYST 1
MENINGIOMA 2 8
NEUROENTERIC CYST 1 1
NEUROFIBROMA 1 2 1
SCHWANNOMA 2 9 7
DIAGNOSIS Anterior Posterior Posterolateral
EPENDYMOMA 1 4
EPIDERMOID CYST 1
MENINGIOMA 5 5
NEUROENTERIC CYST 2
NEUROFIBROMA 3 1
SCHWANNOMA 12 6

GENDER DISTRIBUTION BY DIAGNOSIS

DIAGNOSIS FEMALE MALE
EPENDYMOMA 4 1
EPIDERMOID CYST 1
MENINGIOMA 5 5
NEUROENTERIC CYST 1 1
NEUROFIBROMA 2 2
SCHWANNOMA 11 7

POST OP FRENKEL GRADE DISTRIBUTION

value FC0 FC6W FC12W FC6M
2 6 6 3 3
3 14 7 5 5
4 20 19 21 20
5 8 11 12

improvement by type of tumour

tumorsa variable n mean sd
EPENDYMOMA deltaFC 5 0.400 0.548
MENINGIOMA deltaFC 10 0.500 0.527
NEUROFIBROMA deltaFC 4 1.000 0.000
SCHWANNOMA deltaFC 18 0.722 0.669
Other deltaFC 3 1.000 0.000

We find that One-way ANOVA was non-significant for Group effect of tumorsa on deltaFC. In statistical notation it is expressed as F(4,35)=0.36. The  Effect size(Omega -Squared) of this One-way ANOVA  test was 0.115 .

POST OP PAIN SCALE DISTRIBUTION

value VAS0 VAS6W VAS12W VAS6M
1 3 10
2 10 9 25
3 21 1
4 5 20 7 4
6 24 10
8 9
10 2

improvement in Pain by type of tumour

tumorsa variable n mean sd
EPENDYMOMA deltavas 5 5.200 1.789
MENINGIOMA deltavas 10 3.900 0.738
NEUROFIBROMA deltavas 4 4.750 1.893
SCHWANNOMA deltavas 18 4.278 0.752
Other deltavas 3 5.333 0.577

We find that One-way ANOVA was non-significant for Group effect of tumorsa on deltavas. In statistical notation it is expressed as F(4,35)=0.11. The  Effect size(Omega -Squared) of this One-way ANOVA  test was 0.189 .

CORRELATION BETWEEN DURATION OF SYMPTOMS AND IMPROVEMENT IN FRENKEL GRADE

The scatter plot above shows relationship between DURATION_OF_SYMPTOM on X axis and improvement in Frenkel Grade(FC6M - FC0) on Y axis. Graphically, we see that as DURATION_OF_SYMPTOM increases, improvement in Frenkel Grade decreases . On a formal statistical linear regression analysis, we that line of best fit (blue line signifying line with least square difference) also has a negative slope implying a negative correlation. The gray shaded error around blue line signifies 95% confidence interval of linear regression line of best fit. The correlation between two variables is Significant . The Pearson’s correlation between DURATION_OF_SYMPTOM and improvement in Frenkel Grade is -0.45 with 95% Confidence Interval of -0.67 to -0.16. the t statistic is -3.08 The p value is <0.001 .The degree of freedom is 38. In formal statistical notation this expressed as t(38)= -3.11, P= <0.001. r(Pearson) = -0.45 95% C.I. [-0.67–0.16]. n= 40. The correlation is summmarised in table below

Group 1 Group 2 Degree of Freedom T statistic Correlation 95 % C.I. P value
DURATION_OF_SYMPTOM deltaFC 38 -3.11 -0.45 -0.67–0.16 <0.001
variable n Mean SD Median Minimum Maximum
deltaFC 40 0.675 0.572 1.000 0.000 2.000
DURATION_OF_SYMPTOM 40 9.000 3.000 9.208 2.384 14.712

CORRELATION BETWEEN TUMOR OCCUPANCY AND IMPROVEMENT IN FRENKEL GRADE

The scatter plots above show relationship between OCCUPANCY on X axis and deltaFC on Y axis. Graphically, we see that as OCCUPANCY increases, deltaFC decreases . On a formal statistical linear regression analysis, we that line of best fit (blue line signifying line with least square difference) also has a negative slope implying a negative correlation. The gray shaded error around blue line signifies 95% confidence interval of linear regression line of best fit. The correlation between two variables is Significant . The Pearson’s correlation between OCCUPANCY and deltaFC is -0.34 with 95% Confidence Interval of -0.59 to -0.03. the t statistic is -2.23 The p value is 0.03 .The degree of freedom is 38. In formal statistical notation this expressed as t(38)= -2.23, P= 0.03. r(Pearson) = -0.34 95% C.I. [-0.59–0.03]. n= 40. The correlation is summmarised in table below

The scatter plots above show relationship between OCCUPANCY on X axis and deltaFC on Y axis. Graphically, we see that as OCCUPANCY increases, deltaFC decreases .
On a formal statistical linear regression analysis, we that line of best fit (blue line signifying line with least square difference) also has a negative slope implying a negative correlation.
The gray shaded error around blue line signifies 95% confidence interval of linear regression line of best fit.
The correlation between two variables is Significant . The Pearson's correlation between OCCUPANCY and deltaFC is -0.34 with 95% Confidence Interval of -0.59 to -0.03. the t statistic is -2.23 The p value is 0.03 .The degree of freedom is 38.
In formal statistical notation this expressed as t(38)= -2.23, P= 0.03. r(Pearson) = -0.34 95% C.I. [-0.59--0.03]. n= 40. The correlation is summmarised in table below
Group 1 Group 2 Degree of Freedom T statistic Correlation 95 % C.I. P value
OCCUPANCY deltaFC 38 -2.23 -0.34 -0.59–0.03 0.03
variable n Mean SD Median Minimum Maximum
deltaFC 40 0.675 0.572 1.000 0.000 2.000
OCCUPANCY 40 80.000 5.400 79.869 65.962 90.122

Variation Of VAS with time

This is a trace-plot of variation in Pain Scale (on Y axis) with passage of of time on X-axis , Pain Ratings across various stages are connected by distinct colored trace-line . Individual readings have been plotted on graph and points have been jittered for better clarity . The raw data points representing two groups have different shapes as indicated in the legend. The points across the trace represent the mean readings in two groups and whiskers represent Standard error of measurements.

we can clearly see a negative trend/slope indicating a fall in Pain with passage of Time.we decided to explore this intuitive graphical relationship with formal statistical tests.

key n mean sd
VAS0 40 6.400 1.446
VAS6W 40 4.000 1.432
VAS12W 40 2.800 0.823
VAS6M 40 1.975 0.832
Effect df MSE F ges p.value
key 2.27, 88.65 0.67 291.67 *** .67 <.0001
contrast estimate SE df t.ratio p.value
VAS0 - VAS6W 2.400 0.1595014 117 15.046887 <0.001
VAS0 - VAS12W 3.600 0.1595014 117 22.570331 <0.001
VAS0 - VAS6M 4.425 0.1595014 117 27.742698 <0.001
VAS6W - VAS12W 1.200 0.1595014 117 7.523444 <0.001
VAS6W - VAS6M 2.025 0.1595014 117 12.695811 <0.001
VAS12W - VAS6M 0.825 0.1595014 117 5.172368 <0.001

Change in Frenkel Grade with Time

This is a trace-plot of variation in Frenkel Grade (on Y axis) with passage of of time on X-axis , Frenkel Grade across various stages are connected by distinct colored trace-line . Individual readings have been plotted on graph and points have been jittered for better clarity . The raw data points representing two groups have different shapes as indicated in the legend. The points across the trace represent the mean readings in two groups and whiskers represent Standard error of measurements.

we can clearly see a negative trend/slope indicating a rise / improvement in Frenkel with passage of Time.we decided to explore this intuitive graphical relationship with formal statistical tests.

Effect df MSE F ges p.value
key 1.92, 75.07 0.19 32.66 *** .09 <.0001
contrast estimate SE df t.ratio p.value
FC0 - FC6W -0.375 0.0777625 117 -4.8223750 <0.001
FC0 - FC12W -0.650 0.0777625 117 -8.3587833 <0.001
FC0 - FC6M -0.675 0.0777625 117 -8.6802749 <0.001
FC6W - FC12W -0.275 0.0777625 117 -3.5364083 0.003
FC6W - FC6M -0.300 0.0777625 117 -3.8579000 0.001
FC12W - FC6M -0.025 0.0777625 117 -0.3214917 0.988