R Notebook
Set up
Install packages and load Eunomia and test that it works
library(magrittr)
# library(devtools)
# options(devtools.install.args = "--no-multiarch")
# install_github('OHDSI/DatabaseConnector')
# install_github('OHDSI/SqlRender')
#
# install_github('OHDSI/FeatureExtraction')
# install_github('OHDSI/OhdsiRTools')
# install_github('OHDSI/OhdsiSharing')
# devtools::install_github('OHDSI/Eunomia')
# devtools::install_github('OHDSI/DataQualityDashboard')
# devtools::install_github('OHDSI/PatientLevelPrediction')
#remove.packages('Eunomia')
library(Eunomia)## Loading required package: DatabaseConnectorconnectionDetails <- Eunomia::getEunomiaConnectionDetails()
connection <- connect(connectionDetails)## Connecting using SQLite driverquerySql(connection, "SELECT COUNT(*) FROM person;")## COUNT(*)
## 1 2694DatabaseConnector::disconnect(connection)Run DQD
on Eunomia
library(DataQualityDashboard)
cdmDatabaseSchema<-'main'
resultsDatabaseSchema<-cdmDatabaseSchema
cdmSourceName='eunomia'
outputFolder='c:/temp'
#we can run just one check to make it fast
checkNames=c('plausibleValueLow')
#all checks are here
dashChecks<-read.csv(system.file("csv","OMOP_CDMv5.3.1_Check_Descriptions.csv",package="DataQualityDashboard"),as.is=T)
dashChecks$checkName## [1] "measurePersonCompleteness"
## [2] "cdmField"
## [3] "isRequired"
## [4] "cdmDatatype"
## [5] "isPrimaryKey"
## [6] "isForeignKey"
## [7] "fkDomain"
## [8] "fkClass"
## [9] "isStandardValidConcept"
## [10] "measureValueCompleteness"
## [11] "standardConceptRecordCompleteness"
## [12] "sourceConceptRecordCompleteness"
## [13] "sourceValueCompleteness"
## [14] "plausibleValueLow"
## [15] "plausibleValueHigh"
## [16] "plausibleTemporalAfter"
## [17] "plausibleDuringLife"
## [18] "plausibleValueLow"
## [19] "plausibleValueHigh"
## [20] "plausibleGender"#actual execution
result<-executeDqChecks(connectionDetails,cdmDatabaseSchema
,resultsDatabaseSchema = resultsDatabaseSchema
,cdmSourceName = cdmSourceName
,verboseMode = TRUE
,outputFolder = outputFolder
,checkNames = checkNames)## Connecting using SQLite driver
## Processing check description: plausibleValueLow
## Processing check description: plausibleValueLow
## Connecting using SQLite driver
## Execution Complete
## Connecting using SQLite driverinspecting the results
jsonFile<-file.path(outputFolder,cdmSourceName,paste0('results_',cdmSourceName,'.json'))
#DataQualityDashboard::viewDqDashboard(jsonFile)
jresult<-jsonlite::fromJSON(jsonFile)
overview<-jresult$CheckResults
#value of 1 indicates failed
table(overview$FAILED)##
## 0 1
## 883 26Create Cohorts
library(Eunomia)
cohorts<-Eunomia:::createCohorts(connectionDetails)## Connecting using SQLite driver
## Creating cohort: Celecoxib
##
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## Executing SQL took 0.02 secs
## Creating cohort: Diclofenac
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## Executing SQL took 0.022 secs
## Creating cohort: GiBleed
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## Executing SQL took 0.03 secs
## Creating cohort: NSAIDs
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## Executing SQL took 0.147 secs
## Cohorts created in table main.cohort#list them nicely
knitr::kable(cohorts)| cohortId | name | description | count |
|---|---|---|---|
| 1 | Celecoxib | A simplified cohort definition for new users of celecoxib, designed specifically for Eunomia. | 1844 |
| 2 | Diclofenac | A simplified cohort definition for new users ofdiclofenac, designed specifically for Eunomia. | 850 |
| 3 | GiBleed | A simplified cohort definition for gastrointestinal bleeding, designed specifically for Eunomia. | 479 |
| 4 | NSAIDs | A simplified cohort definition for new users of NSAIDs, designed specifically for Eunomia. | 2694 |
Cohort Characterization
Link https://ohdsi.github.io/TheBookOfOhdsi/Characterization.html#cohort-characterization-in-r
We can use cohorts created earlier.
library(FeatureExtraction)
#basic settings
settings<-createCovariateSettings(useDemographicsGender = TRUE
,useDemographicsAgeGroup = TRUE
,useConditionOccurrenceAnyTimePrior = TRUE)
str(settings)## List of 13
## $ temporal : logi FALSE
## $ DemographicsGender : logi TRUE
## $ DemographicsAgeGroup : logi TRUE
## $ ConditionOccurrenceAnyTimePrior: logi TRUE
## $ longTermStartDays : num -365
## $ mediumTermStartDays : num -180
## $ shortTermStartDays : num -30
## $ endDays : num 0
## $ includedCovariateConceptIds : logi(0)
## $ addDescendantsToInclude : logi FALSE
## $ excludedCovariateConceptIds : logi(0)
## $ addDescendantsToExclude : logi FALSE
## $ includedCovariateIds : logi(0)
## - attr(*, "fun")= chr "getDbDefaultCovariateData"
## - attr(*, "class")= chr "covariateSettings"#default settings
covariateSettings<-createDefaultCovariateSettings()
str(covariateSettings)## List of 34
## $ temporal : logi FALSE
## $ DemographicsGender : logi TRUE
## $ DemographicsAgeGroup : logi TRUE
## $ DemographicsRace : logi TRUE
## $ DemographicsEthnicity : logi TRUE
## $ DemographicsIndexYear : logi TRUE
## $ DemographicsIndexMonth : logi TRUE
## $ ConditionGroupEraLongTerm : logi TRUE
## $ ConditionGroupEraShortTerm : logi TRUE
## $ DrugGroupEraLongTerm : logi TRUE
## $ DrugGroupEraShortTerm : logi TRUE
## $ DrugGroupEraOverlapping : logi TRUE
## $ ProcedureOccurrenceLongTerm : logi TRUE
## $ ProcedureOccurrenceShortTerm : logi TRUE
## $ DeviceExposureLongTerm : logi TRUE
## $ DeviceExposureShortTerm : logi TRUE
## $ MeasurementLongTerm : logi TRUE
## $ MeasurementShortTerm : logi TRUE
## $ MeasurementRangeGroupLongTerm: logi TRUE
## $ ObservationLongTerm : logi TRUE
## $ ObservationShortTerm : logi TRUE
## $ CharlsonIndex : logi TRUE
## $ Dcsi : logi TRUE
## $ Chads2 : logi TRUE
## $ Chads2Vasc : logi TRUE
## $ includedCovariateConceptIds : logi(0)
## $ includedCovariateIds : logi(0)
## $ addDescendantsToInclude : logi FALSE
## $ excludedCovariateConceptIds : logi(0)
## $ addDescendantsToExclude : logi FALSE
## $ shortTermStartDays : int -30
## $ mediumTermStartDays : int -180
## $ endDays : int 0
## $ longTermStartDays : int -365
## - attr(*, "fun")= chr "getDbDefaultCovariateData"
## - attr(*, "class")= chr "covariateSettings"#cohort 1 is celecoxib
covariateData2 <- getDbCovariateData(
connectionDetails = connectionDetails,
cdmDatabaseSchema = cdmDatabaseSchema,
cohortDatabaseSchema = resultsDatabaseSchema,
#cohortTable = "cohorts_of_interest",
cohortId = 1,
covariateSettings = covariateSettings,
aggregated = TRUE) ## Connecting using SQLite driver
## Constructing features on server
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## Executing SQL took 3.17 secs
## Fetching data from server
## Fetching data took 0.339 secssummary(covariateData2)## CovariateData object summary
##
## Number of covariates: 373
## Number of non-zero covariate values: 373Inspecting covariate data
#I think it goes to a temp table, but temp tables are not visible in sqlLite
#DatabaseConnector::getTableNames(connection)
#there are two types of covariates
names(covariateData2)## [1] "covariates" "covariatesContinuous" "covariateRef"
## [4] "analysisRef" "metaData"#reference
#sql fo each analysis is here https://github.com/OHDSI/FeatureExtraction/tree/master/inst/sql/sql_server
ana<-covariateData2$analysisRef %>% as.data.frame()
knitr::kable(ana)| analysisId | analysisName | domainId | startDay | endDay | isBinary | missingMeansZero |
|---|---|---|---|---|---|---|
| 212 | ConditionGroupEraShortTerm | Condition | -30 | 0 | Y | NA |
| 804 | ObservationShortTerm | Observation | -30 | 0 | Y | NA |
| 602 | DeviceExposureLongTerm | Device | -365 | 0 | Y | NA |
| 4 | DemographicsRace | Demographics | NA | NA | Y | NA |
| 901 | CharlsonIndex | Condition | NA | 0 | N | Y |
| 904 | Chads2Vasc | Condition | NA | 0 | N | Y |
| 704 | MeasurementShortTerm | Measurement | -30 | 0 | Y | NA |
| 902 | Dcsi | Condition | NA | 0 | N | Y |
| 410 | DrugGroupEraLongTerm | Drug | -365 | 0 | Y | NA |
| 412 | DrugGroupEraShortTerm | Drug | -30 | 0 | Y | NA |
| 702 | MeasurementLongTerm | Measurement | -365 | 0 | Y | NA |
| 6 | DemographicsIndexYear | Demographics | NA | NA | Y | NA |
| 7 | DemographicsIndexMonth | Demographics | NA | NA | Y | NA |
| 210 | ConditionGroupEraLongTerm | Condition | -365 | 0 | Y | NA |
| 5 | DemographicsEthnicity | Demographics | NA | NA | Y | NA |
| 1 | DemographicsGender | Demographics | NA | NA | Y | NA |
| 604 | DeviceExposureShortTerm | Device | -30 | 0 | Y | NA |
| 802 | ObservationLongTerm | Observation | -365 | 0 | Y | NA |
| 502 | ProcedureOccurrenceLongTerm | Procedure | -365 | 0 | Y | NA |
| 3 | DemographicsAgeGroup | Demographics | NA | NA | Y | NA |
| 710 | MeasurementRangeGroupLongTerm | -365 | 0 | Y | NA | |
| 413 | DrugGroupEraOverlapping | Drug | 0 | 0 | Y | NA |
| 504 | ProcedureOccurrenceShortTerm | Procedure | -30 | 0 | Y | NA |
| 903 | Chads2 | Condition | NA | 0 | N | Y |
#next we look at covariates (listing just few)
cov<-covariateData2$covariateRef %>% as.data.frame()
nrow(cov)## [1] 373knitr::kable(cov %>% head(10))| covariateId | covariateName | analysisId | conceptId |
|---|---|---|---|
| 28060212 | condition_era group during day -30 through 0 days relative to index: Streptococcal sore throat | 212 | 28060 |
| 78272212 | condition_era group during day -30 through 0 days relative to index: Sprain of wrist | 212 | 78272 |
| 80180212 | condition_era group during day -30 through 0 days relative to index: Osteoarthritis | 212 | 80180 |
| 80809212 | condition_era group during day -30 through 0 days relative to index: Rheumatoid arthritis | 212 | 80809 |
| 134438212 | condition_era group during day -30 through 0 days relative to index: Contact dermatitis | 212 | 134438 |
| 195588212 | condition_era group during day -30 through 0 days relative to index: Cystitis | 212 | 195588 |
| 257012212 | condition_era group during day -30 through 0 days relative to index: Chronic sinusitis | 212 | 257012 |
| 260139212 | condition_era group during day -30 through 0 days relative to index: Acute bronchitis | 212 | 260139 |
| 317576212 | condition_era group during day -30 through 0 days relative to index: Coronary arteriosclerosis | 212 | 317576 |
| 372328212 | condition_era group during day -30 through 0 days relative to index: Otitis media | 212 | 372328 |
#each analysis underpins several covariates
table(cov$analysisId)##
## 1 3 6 7 210 212 410 412 413 502 504 702 704 802 901 903 904
## 2 4 78 12 51 31 46 24 11 27 12 48 22 2 1 1 1#we can merget them to both (not done)PLP
library(PatientLevelPrediction)## Loading required package: Cyclops## Registered S3 methods overwritten by 'ffbase':
## method from
## [.ff ff
## [.ffdf ff
## [<-.ff ff
## [<-.ffdf ff##
## Attaching package: 'PatientLevelPrediction'## The following object is masked from 'package:FeatureExtraction':
##
## bySumFfcohorts<-Eunomia:::createCohorts(connectionDetails)## Connecting using SQLite driver
## Creating cohort: Celecoxib
##
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## Executing SQL took 0.015 secs
## Creating cohort: Diclofenac
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## Executing SQL took 0.021 secs
## Creating cohort: GiBleed
##
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## Executing SQL took 0.028 secs
## Creating cohort: NSAIDs
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## Executing SQL took 0.126 secs
## Cohorts created in table main.cohortcovSettings <- createCovariateSettings(
useDemographicsGender = TRUE,
useDemographicsAge = TRUE,
useConditionGroupEraLongTerm = TRUE,
useConditionGroupEraAnyTimePrior = TRUE,
useDrugGroupEraLongTerm = TRUE,
useDrugGroupEraAnyTimePrior = TRUE,
useVisitConceptCountLongTerm = TRUE,
longTermStartDays = -365,
endDays = -1)
plpData <- getPlpData(connectionDetails = connectionDetails,
cdmDatabaseSchema = "main",
cohortDatabaseSchema = "main",
cohortTable = "cohort",
cohortId = 4,
covariateSettings = covSettings,
outcomeDatabaseSchema = "main",
outcomeTable = "cohort",
outcomeIds = 3)## Connecting using SQLite driver
##
## Constructing the at risk cohort
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## Executing SQL took 0.016 secs
## Fetching cohorts from server
## Loading cohorts took 0.057 secs
## Constructing features on server
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## Executing SQL took 1.89 secs
## Fetching data from server
## Fetching data took 0.375 secs
## Fetching outcomes from server
## Loading outcomes took 0.064 secssummary(plpData)## plpData object summary
##
## At risk cohort concept ID: -1
## Outcome concept ID(s): 3
##
## People: 2630
##
## Outcome counts:
## Event count Person count
## 3 479 479
##
## Covariates:
## Number of covariates: 245
## Number of non-zero covariate values: 54079#str(plpData)
#feature extraction does analyses. OVerview of them is here
aref<-as.data.frame(plpData$analysisRef )
knitr::kable(aref)| analysisId | analysisName | domainId | startDay | endDay | isBinary | missingMeansZero |
|---|---|---|---|---|---|---|
| 210 | ConditionGroupEraLongTerm | Condition | -365 | -1 | Y | NA |
| 1 | DemographicsGender | Demographics | NA | NA | Y | NA |
| 923 | VisitConceptCountLongTerm | Visit | NA | NA | N | Y |
| 2 | DemographicsAge | Demographics | NA | NA | N | Y |
| 409 | DrugGroupEraAnyTimePrior | Drug | NA | -1 | Y | NA |
| 410 | DrugGroupEraLongTerm | Drug | -365 | -1 | Y | NA |
| 209 | ConditionGroupEraAnyTimePrior | Condition | NA | -1 | Y | NA |
population <- createStudyPopulation(plpData = plpData,
outcomeId = 3,
washoutPeriod = 364,
firstExposureOnly = FALSE,
removeSubjectsWithPriorOutcome = TRUE,
priorOutcomeLookback = 9999,
riskWindowStart = 1,
riskWindowEnd = 365,
addExposureDaysToStart = FALSE,
addExposureDaysToEnd = FALSE,
minTimeAtRisk = 364,
requireTimeAtRisk = TRUE,
includeAllOutcomes = TRUE)## 2019-11-15 09:17:39 Outcome is 0 or 1nrow(population)## [1] 2578lassoModel <- setLassoLogisticRegression(seed = 0)
lassoResults <- runPlp(population = population,
plpData = plpData,
modelSettings = lassoModel,
testSplit = 'person',
testFraction = 0.25,
nfold = 2,
splitSeed = 0)## 2019-11-15 09:17:39 Patient-Level Prediction Package version 3.0.8
## 2019-11-15 09:17:39 AnalysisID: 20191115091739
## 2019-11-15 09:17:39 CohortID: 4
## 2019-11-15 09:17:39 OutcomeID: 3
## 2019-11-15 09:17:39 Cohort size: 2630
## 2019-11-15 09:17:39 Covariates: 245
## 2019-11-15 09:17:39 Population size: 2578
## 2019-11-15 09:17:39 Cases: 479
## 2019-11-15 09:17:39 Saving plpData to O:/r/sandohdsi/20191115091739/plpData## Warning: 'personSplitter' is deprecated.
## Use 'randomSplitter' instead.
## See help("Deprecated")## 2019-11-15 09:17:40 Creating a 25% test and 75% train (into 2 folds) random stratified split by class
## 2019-11-15 09:17:40 Data split into 645 test cases and 1933 train cases (967, 966)
## 2019-11-15 09:17:40 Training Lasso Logistic Regression model
## Removing redundant covariates
## Removing redundant covariates took 0.02 secs
## Removing infrequent covariates
## Removing infrequent covariates took 0.13 secs
## Normalizing covariates
## Normalizing covariates took 0.266 secs
## 2019-11-15 09:17:41 Running Cyclops
## 2019-11-15 09:17:42 Done.
## 2019-11-15 09:17:42 GLM fit status: OK
## 2019-11-15 09:17:42 Fitting model took 0.638 secs
## 2019-11-15 09:17:42 Creating variable importance data frame
## 2019-11-15 09:17:42 Getting predictions on train set
## 2019-11-15 09:17:42 Prediction took 0.112 secs
## Removing infrequent covariates
## Removing infrequent covariates took 0.078 secs
## Normalizing covariates
## Normalizing covariates took 0.109 secs
## Removing redundant covariates
## Removing redundant covariates took 0.301 secs
## 2019-11-15 09:17:43 Prediction took 0.108 secs
## 2019-11-15 09:17:43 Train set evaluation
## 2019-11-15 09:17:43 AUC: 71.12
## 2019-11-15 09:17:43 95% lower AUC: 68.15
## 2019-11-15 09:17:43 95% upper AUC: 74.09
## 2019-11-15 09:17:43 AUPRC: 36.15
## 2019-11-15 09:17:43 Brier: 0.14
## 2019-11-15 09:17:44 Calibration gradient: 1.14 intercept: -0.03
## 2019-11-15 09:17:44 Average Precision: 0.36
## 2019-11-15 09:17:44 Test set evaluation
## 2019-11-15 09:17:44 AUC: 64.45
## 2019-11-15 09:17:44 95% lower AUC: 58.90
## 2019-11-15 09:17:44 95% upper AUC: 70.01
## 2019-11-15 09:17:44 AUPRC: 28.63
## 2019-11-15 09:17:44 Brier: 0.14
## 2019-11-15 09:17:45 Calibration gradient: 0.79 intercept: 0.04
## 2019-11-15 09:17:45 Average Precision: 0.29
## 2019-11-15 09:17:45 Calculating covariate summary @ 2019-11-15 09:17:45
## 2019-11-15 09:17:45 This can take a while...
## 2019-11-15 09:17:46 Finished covariate summary @ 2019-11-15 09:17:46## Warning: Removed 4 rows containing missing values (geom_point).
## 2019-11-15 09:17:52 Saving PlpResult
## 2019-11-15 09:17:52 plpResult saved to ..\O:/r/sandohdsi/20191115091739\plpResult
## 2019-11-15 09:17:52 Log saved to O:/r/sandohdsi/20191115091739/plplog.txt
## 2019-11-15 09:17:52 Run finished successfully.#viewPlp(lassoResults)
#look at data manually
#str(lassoResults)
names(lassoResults)## [1] "inputSetting" "executionSummary" "model"
## [4] "prediction" "performanceEvaluation" "covariateSummary"
## [7] "analysisRef"#lassoResults$analysisRef
knitr::kable(lassoResults$covariateSummary)| covariateId | analysisId | conceptId | covariateValue | covariateName | CovariateCount | CovariateCountWithOutcome | CovariateMeanWithOutcome | CovariateStDevWithOutcome | CovariateCountWithNoOutcome | CovariateMeanWithNoOutcome | CovariateStDevWithNoOutcome | TrainCovariateCount | TrainCovariateCountWithOutcome | TrainCovariateMeanWithOutcome | TrainCovariateStDevWithOutcome | TrainCovariateCountWithNoOutcome | TrainCovariateMeanWithNoOutcome | TrainCovariateStDevWithNoOutcome | TestCovariateCount | TestCovariateCountWithOutcome | TestCovariateMeanWithOutcome | TestCovariateStDevWithOutcome | TestCovariateCountWithNoOutcome | TestCovariateMeanWithNoOutcome | TestCovariateStDevWithNoOutcome |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1002 | 2 | 0 | 0.0000000 | age in years | 2578 | 479 | 38.7995825 | 3.3042257 | 2099 | 38.5712244 | 3.3074217 | 1933 | 359 | 38.7604457 | 3.2782499 | 1574 | 38.5902160 | 3.2964071 | 645 | 120 | 38.9166667 | 3.3919909 | 525 | 38.5142857 | 3.3427439 |
| 8507001 | 1 | 8507 | 0.0000000 | gender = Unknown concept | 1262 | 237 | 0.4947808 | 0.5004955 | 1025 | 0.4883278 | 0.4999829 | 947 | 176 | 0.4902507 | 0.5006026 | 771 | 0.4898348 | 0.5000555 | 315 | 61 | 0.5083333 | 0.5020267 | 254 | 0.4838095 | 0.5002144 |
| 8532001 | 1 | 8532 | 0.0000000 | gender = Unknown concept | 1316 | 242 | 0.5052192 | 0.5004955 | 1074 | 0.5116722 | 0.4999829 | 986 | 183 | 0.5097493 | 0.5006026 | 803 | 0.5101652 | 0.5000555 | 330 | 59 | 0.4916667 | 0.5020267 | 271 | 0.5161905 | 0.5002144 |
| 9201923 | 923 | 0 | 0.0000000 | visit_occurrence concept count during day -365 through -1 concept_count relative to index: Inpatient Visit | 4 | 0 | 0.0000000 | 0.0000000 | 4 | 0.0019057 | 0.0436228 | 4 | 0 | 0.0000000 | 0.0000000 | 4 | 0.0025413 | 0.0503632 | NA | NA | NA | NA | NA | NA | NA |
| 28060209 | 209 | 28060 | 0.0000000 | condition_era group any time prior through -1 days relative to index: Streptococcal sore throat | 1367 | 265 | 0.5532359 | 0.4976776 | 1102 | 0.5250119 | 0.4994930 | 1020 | 199 | 0.5543175 | 0.4977346 | 821 | 0.5216010 | 0.4996919 | 347 | 66 | 0.5500000 | 0.4995797 | 281 | 0.5352381 | 0.4992324 |
| 28060210 | 210 | 28060 | 0.0000000 | condition_era group during day -365 through -1 days relative to index: Streptococcal sore throat | 22 | 7 | 0.0146138 | 0.1201264 | 15 | 0.0071463 | 0.0842530 | 21 | 7 | 0.0194986 | 0.1384623 | 14 | 0.0088945 | 0.0939203 | 1 | 0 | 0.0000000 | 0.0000000 | 1 | 0.0019048 | 0.0436436 |
| 30753209 | 209 | 30753 | 0.1290896 | condition_era group any time prior through -1 days relative to index: Esophagitis | 397 | 134 | 0.2797495 | 0.4493453 | 263 | 0.1252978 | 0.3311351 | 289 | 110 | 0.3064067 | 0.4616441 | 179 | 0.1137230 | 0.3175754 | 108 | 24 | 0.2000000 | 0.4016772 | 84 | 0.1600000 | 0.3669557 |
| 30753210 | 210 | 30753 | 0.0000000 | condition_era group during day -365 through -1 days relative to index: Esophagitis | 216 | 66 | 0.1377871 | 0.3450367 | 150 | 0.0714626 | 0.2576574 | 153 | 52 | 0.1448468 | 0.3524375 | 101 | 0.0641677 | 0.2451294 | 63 | 14 | 0.1166667 | 0.3223687 | 49 | 0.0933333 | 0.2911764 |
| 78272209 | 209 | 78272 | 0.1126913 | condition_era group any time prior through -1 days relative to index: Sprain of wrist | 502 | 105 | 0.2192067 | 0.4141415 | 397 | 0.1891377 | 0.3917113 | 380 | 84 | 0.2339833 | 0.4239526 | 296 | 0.1880559 | 0.3908810 | 122 | 21 | 0.1750000 | 0.3815603 | 101 | 0.1923810 | 0.3945466 |
| 78272210 | 210 | 78272 | 0.0000000 | condition_era group during day -365 through -1 days relative to index: Sprain of wrist | 14 | 4 | 0.0083507 | 0.0910951 | 10 | 0.0047642 | 0.0688748 | 14 | 4 | 0.0111421 | 0.1051128 | 10 | 0.0063532 | 0.0794789 | NA | NA | NA | NA | NA | NA | NA |
| 80809209 | 209 | 80809 | 0.0000000 | condition_era group any time prior through -1 days relative to index: Rheumatoid arthritis | 6 | 2 | 0.0041754 | 0.0645494 | 4 | 0.0019057 | 0.0436228 | 4 | 1 | 0.0027855 | 0.0527780 | 3 | 0.0019060 | 0.0436297 | 2 | 1 | 0.0083333 | 0.0912871 | 1 | 0.0019048 | 0.0436436 |
| 80809210 | NA | NA | 0.0000000 | condition_era group during day -365 through -1 days relative to index: Rheumatoid arthritis | 1 | 0 | 0.0000000 | 0.0000000 | 1 | 0.0004764 | 0.0218270 | NA | NA | NA | NA | NA | NA | NA | 1 | 0 | 0.0000000 | 0.0000000 | 1 | 0.0019048 | 0.0436436 |
| 81151209 | 209 | 81151 | -0.0107679 | condition_era group any time prior through -1 days relative to index: Sprain of ankle | 1033 | 180 | 0.3757829 | 0.4848307 | 853 | 0.4063840 | 0.4912749 | 777 | 134 | 0.3732591 | 0.4843451 | 643 | 0.4085133 | 0.4917152 | 256 | 46 | 0.3833333 | 0.4882370 | 210 | 0.4000000 | 0.4903652 |
| 81151210 | 210 | 81151 | 0.0000000 | condition_era group during day -365 through -1 days relative to index: Sprain of ankle | 26 | 6 | 0.0125261 | 0.1113331 | 20 | 0.0095283 | 0.0971702 | 20 | 5 | 0.0139276 | 0.1173540 | 15 | 0.0095299 | 0.0971856 | 6 | 1 | 0.0083333 | 0.0912871 | 5 | 0.0095238 | 0.0972168 |
| 81893209 | 209 | 81893 | 0.0000000 | condition_era group any time prior through -1 days relative to index: Ulcerative colitis | 402 | 130 | 0.2713987 | 0.4451462 | 272 | 0.1295855 | 0.3359269 | 299 | 99 | 0.2757660 | 0.4475232 | 200 | 0.1270648 | 0.3331514 | 103 | 31 | 0.2583333 | 0.4395535 | 72 | 0.1371429 | 0.3443262 |
| 81893210 | 210 | 81893 | 0.0000000 | condition_era group during day -365 through -1 days relative to index: Ulcerative colitis | 65 | 20 | 0.0417537 | 0.2002348 | 45 | 0.0214388 | 0.1448764 | 53 | 17 | 0.0473538 | 0.2126908 | 36 | 0.0228717 | 0.1495418 | 12 | 3 | 0.0250000 | 0.1567796 | 9 | 0.0171429 | 0.1299274 |
| 133834209 | 209 | 133834 | 0.0000000 | condition_era group any time prior through -1 days relative to index: Atopic dermatitis | 50 | 5 | 0.0104384 | 0.1017402 | 45 | 0.0214388 | 0.1448764 | 34 | 3 | 0.0083565 | 0.0911584 | 31 | 0.0196950 | 0.1389943 | 16 | 2 | 0.0166667 | 0.1285559 | 14 | 0.0266667 | 0.1612609 |
| 134438209 | 209 | 134438 | 0.0000000 | condition_era group any time prior through -1 days relative to index: Contact dermatitis | 107 | 15 | 0.0313152 | 0.1743504 | 92 | 0.0438304 | 0.2047664 | 74 | 12 | 0.0334262 | 0.1799976 | 62 | 0.0393901 | 0.1945831 | 33 | 3 | 0.0250000 | 0.1567796 | 30 | 0.0571429 | 0.2323368 |
| 134438210 | 210 | 134438 | 0.0000000 | condition_era group during day -365 through -1 days relative to index: Contact dermatitis | 3 | 1 | 0.0020877 | 0.0456912 | 2 | 0.0009528 | 0.0308607 | 2 | 0 | 0.0000000 | 0.0000000 | 2 | 0.0012706 | 0.0356348 | 1 | 1 | 0.0083333 | 0.0912871 | 0 | 0.0000000 | 0.0000000 |
| 195588209 | 209 | 195588 | 0.0000000 | condition_era group any time prior through -1 days relative to index: Cystitis | 169 | 38 | 0.0793319 | 0.2705387 | 131 | 0.0624107 | 0.2419576 | 127 | 31 | 0.0863510 | 0.2812736 | 96 | 0.0609911 | 0.2393901 | 42 | 7 | 0.0583333 | 0.2353554 | 35 | 0.0666667 | 0.2496817 |
| 195588210 | 210 | 195588 | 0.0000000 | condition_era group during day -365 through -1 days relative to index: Cystitis | 13 | 3 | 0.0062630 | 0.0789737 | 10 | 0.0047642 | 0.0688748 | 9 | 2 | 0.0055710 | 0.0745350 | 7 | 0.0044473 | 0.0665605 | 4 | 1 | 0.0083333 | 0.0912871 | 3 | 0.0057143 | 0.0754485 |
| 196456209 | 209 | 196456 | 0.0000000 | condition_era group any time prior through -1 days relative to index: Gallstone | 24 | 5 | 0.0104384 | 0.1017402 | 19 | 0.0090519 | 0.0947326 | 20 | 5 | 0.0139276 | 0.1173540 | 15 | 0.0095299 | 0.0971856 | 4 | 0 | 0.0000000 | 0.0000000 | 4 | 0.0076190 | 0.0870369 |
| 196456210 | NA | NA | 0.0000000 | condition_era group during day -365 through -1 days relative to index: Gallstone | 1 | 0 | 0.0000000 | 0.0000000 | 1 | 0.0004764 | 0.0218270 | 1 | 0 | 0.0000000 | 0.0000000 | 1 | 0.0006353 | 0.0252056 | NA | NA | NA | NA | NA | NA | NA |
| 198199209 | 209 | 198199 | 0.0000000 | condition_era group any time prior through -1 days relative to index: Pyelonephritis | 4 | 2 | 0.0041754 | 0.0645494 | 2 | 0.0009528 | 0.0308607 | 3 | 2 | 0.0055710 | 0.0745350 | 1 | 0.0006353 | 0.0252056 | 1 | 0 | 0.0000000 | 0.0000000 | 1 | 0.0019048 | 0.0436436 |
| 198199210 | NA | NA | 0.0000000 | condition_era group during day -365 through -1 days relative to index: Pyelonephritis | 1 | 1 | 0.0020877 | 0.0456912 | 0 | 0.0000000 | 0.0000000 | 1 | 1 | 0.0027855 | 0.0527780 | 0 | 0.0000000 | 0.0000000 | NA | NA | NA | NA | NA | NA | NA |
| 198809209 | 209 | 198809 | 0.0000000 | condition_era group any time prior through -1 days relative to index: Acute cholecystitis | 24 | 5 | 0.0104384 | 0.1017402 | 19 | 0.0090519 | 0.0947326 | 20 | 5 | 0.0139276 | 0.1173540 | 15 | 0.0095299 | 0.0971856 | 4 | 0 | 0.0000000 | 0.0000000 | 4 | 0.0076190 | 0.0870369 |
| 198809210 | NA | NA | 0.0000000 | condition_era group during day -365 through -1 days relative to index: Acute cholecystitis | 1 | 0 | 0.0000000 | 0.0000000 | 1 | 0.0004764 | 0.0218270 | 1 | 0 | 0.0000000 | 0.0000000 | 1 | 0.0006353 | 0.0252056 | NA | NA | NA | NA | NA | NA | NA |
| 257012209 | 209 | 257012 | 0.0000000 | condition_era group any time prior through -1 days relative to index: Chronic sinusitis | 540 | 101 | 0.2108559 | 0.4083428 | 439 | 0.2091472 | 0.4067966 | 415 | 76 | 0.2116992 | 0.4090829 | 339 | 0.2153748 | 0.4112128 | 125 | 25 | 0.2083333 | 0.4078192 | 100 | 0.1904762 | 0.3930512 |
| 257012210 | 210 | 257012 | 0.0000000 | condition_era group during day -365 through -1 days relative to index: Chronic sinusitis | 23 | 2 | 0.0041754 | 0.0645494 | 21 | 0.0100048 | 0.0995459 | 18 | 2 | 0.0055710 | 0.0745350 | 16 | 0.0101652 | 0.1003407 | 5 | 0 | 0.0000000 | 0.0000000 | 5 | 0.0095238 | 0.0972168 |
| 258780209 | 209 | 258780 | 0.0000000 | condition_era group any time prior through -1 days relative to index: Emphysematous bronchitis | 22 | 3 | 0.0062630 | 0.0789737 | 19 | 0.0090519 | 0.0947326 | 16 | 2 | 0.0055710 | 0.0745350 | 14 | 0.0088945 | 0.0939203 | 6 | 1 | 0.0083333 | 0.0912871 | 5 | 0.0095238 | 0.0972168 |
| 258780210 | NA | NA | 0.0000000 | condition_era group during day -365 through -1 days relative to index: Emphysematous bronchitis | 1 | 1 | 0.0020877 | 0.0456912 | 0 | 0.0000000 | 0.0000000 | 1 | 1 | 0.0027855 | 0.0527780 | 0 | 0.0000000 | 0.0000000 | NA | NA | NA | NA | NA | NA | NA |
| 260139209 | 209 | 260139 | 0.0000000 | condition_era group any time prior through -1 days relative to index: Acute bronchitis | 2248 | 411 | 0.8580376 | 0.3493765 | 1837 | 0.8751787 | 0.3305950 | 1689 | 308 | 0.8579387 | 0.3496002 | 1381 | 0.8773825 | 0.3281019 | 559 | 103 | 0.8583333 | 0.3501700 | 456 | 0.8685714 | 0.3381907 |
| 260139210 | 210 | 260139 | 0.0000000 | condition_era group during day -365 through -1 days relative to index: Acute bronchitis | 122 | 17 | 0.0354906 | 0.1852097 | 105 | 0.0500238 | 0.2180461 | 86 | 11 | 0.0306407 | 0.1725827 | 75 | 0.0476493 | 0.2130908 | 36 | 6 | 0.0500000 | 0.2188588 | 30 | 0.0571429 | 0.2323368 |
| 261325209 | 209 | 261325 | 0.0000000 | condition_era group any time prior through -1 days relative to index: Pulmonary emphysema | 33 | 9 | 0.0187891 | 0.1359216 | 24 | 0.0114340 | 0.1063422 | 26 | 7 | 0.0194986 | 0.1384623 | 19 | 0.0120712 | 0.1092384 | 7 | 2 | 0.0166667 | 0.1285559 | 5 | 0.0095238 | 0.0972168 |
| 261325210 | NA | NA | 0.0000000 | condition_era group during day -365 through -1 days relative to index: Pulmonary emphysema | 1 | 0 | 0.0000000 | 0.0000000 | 1 | 0.0004764 | 0.0218270 | 1 | 0 | 0.0000000 | 0.0000000 | 1 | 0.0006353 | 0.0252056 | NA | NA | NA | NA | NA | NA | NA |
| 317009209 | 209 | 317009 | 0.0000000 | condition_era group any time prior through -1 days relative to index: Asthma | 93 | 13 | 0.0271399 | 0.1626608 | 80 | 0.0381134 | 0.1915156 | 66 | 11 | 0.0306407 | 0.1725827 | 55 | 0.0349428 | 0.1836934 | 27 | 2 | 0.0166667 | 0.1285559 | 25 | 0.0476190 | 0.2131620 |
| 317576209 | 209 | 317576 | 0.0000000 | condition_era group any time prior through -1 days relative to index: Coronary arteriosclerosis | 55 | 10 | 0.0208768 | 0.1431214 | 45 | 0.0214388 | 0.1448764 | 44 | 8 | 0.0222841 | 0.1478120 | 36 | 0.0228717 | 0.1495418 | 11 | 2 | 0.0166667 | 0.1285559 | 9 | 0.0171429 | 0.1299274 |
| 317576210 | 210 | 317576 | 0.0000000 | condition_era group during day -365 through -1 days relative to index: Coronary arteriosclerosis | 4 | 0 | 0.0000000 | 0.0000000 | 4 | 0.0019057 | 0.0436228 | 3 | 0 | 0.0000000 | 0.0000000 | 3 | 0.0019060 | 0.0436297 | 1 | 0 | 0.0000000 | 0.0000000 | 1 | 0.0019048 | 0.0436436 |
| 321042209 | 209 | 321042 | 0.0000000 | condition_era group any time prior through -1 days relative to index: Cardiac arrest | 66 | 11 | 0.0229645 | 0.1499469 | 55 | 0.0262030 | 0.1597765 | 51 | 11 | 0.0306407 | 0.1725827 | 40 | 0.0254130 | 0.1574258 | 15 | 0 | 0.0000000 | 0.0000000 | 15 | 0.0285714 | 0.1667575 |
| 321042210 | 210 | 321042 | 0.0000000 | condition_era group during day -365 through -1 days relative to index: Cardiac arrest | 2 | 0 | 0.0000000 | 0.0000000 | 2 | 0.0009528 | 0.0308607 | 2 | 0 | 0.0000000 | 0.0000000 | 2 | 0.0012706 | 0.0356348 | NA | NA | NA | NA | NA | NA | NA |
| 372328209 | 209 | 372328 | 0.0000000 | condition_era group any time prior through -1 days relative to index: Otitis media | 1897 | 342 | 0.7139875 | 0.4523677 | 1555 | 0.7408290 | 0.4382841 | 1429 | 257 | 0.7158774 | 0.4516249 | 1172 | 0.7445997 | 0.4362246 | 468 | 85 | 0.7083333 | 0.4564355 | 383 | 0.7295238 | 0.4446295 |
| 372328210 | 210 | 372328 | 0.0000000 | condition_era group during day -365 through -1 days relative to index: Otitis media | 12 | 1 | 0.0020877 | 0.0456912 | 11 | 0.0052406 | 0.0722192 | 7 | 0 | 0.0000000 | 0.0000000 | 7 | 0.0044473 | 0.0665605 | 5 | 1 | 0.0083333 | 0.0912871 | 4 | 0.0076190 | 0.0870369 |
| 375671209 | 209 | 375671 | 0.0000000 | condition_era group any time prior through -1 days relative to index: Concussion with loss of consciousness | 166 | 37 | 0.0772443 | 0.2672577 | 129 | 0.0614578 | 0.2402254 | 116 | 27 | 0.0752089 | 0.2640962 | 89 | 0.0565438 | 0.2310423 | 50 | 10 | 0.0833333 | 0.2775443 | 40 | 0.0761905 | 0.2655557 |
| 375671210 | 210 | 375671 | 0.0000000 | condition_era group during day -365 through -1 days relative to index: Concussion with loss of consciousness | 6 | 0 | 0.0000000 | 0.0000000 | 6 | 0.0028585 | 0.0534012 | 5 | 0 | 0.0000000 | 0.0000000 | 5 | 0.0031766 | 0.0562898 | 1 | 0 | 0.0000000 | 0.0000000 | 1 | 0.0019048 | 0.0436436 |
| 378001209 | 209 | 378001 | -0.0280880 | condition_era group any time prior through -1 days relative to index: Concussion with no loss of consciousness | 617 | 103 | 0.2150313 | 0.4112736 | 514 | 0.2448785 | 0.4301176 | 482 | 82 | 0.2284123 | 0.4203955 | 400 | 0.2541296 | 0.4355092 | 135 | 21 | 0.1750000 | 0.3815603 | 114 | 0.2171429 | 0.4126939 |
| 378001210 | 210 | 378001 | 0.0000000 | condition_era group during day -365 through -1 days relative to index: Concussion with no loss of consciousness | 20 | 3 | 0.0062630 | 0.0789737 | 17 | 0.0080991 | 0.0896511 | 13 | 1 | 0.0027855 | 0.0527780 | 12 | 0.0076239 | 0.0870090 | 7 | 2 | 0.0166667 | 0.1285559 | 5 | 0.0095238 | 0.0972168 |
| 380378209 | 209 | 380378 | 0.0000000 | condition_era group any time prior through -1 days relative to index: Epilepsy | 23 | 3 | 0.0062630 | 0.0789737 | 20 | 0.0095283 | 0.0971702 | 17 | 3 | 0.0083565 | 0.0911584 | 14 | 0.0088945 | 0.0939203 | 6 | 0 | 0.0000000 | 0.0000000 | 6 | 0.0114286 | 0.1063932 |
| 381316209 | 209 | 381316 | 0.0000000 | condition_era group any time prior through -1 days relative to index: Cerebrovascular accident | 21 | 9 | 0.0187891 | 0.1359216 | 12 | 0.0057170 | 0.0754124 | 12 | 5 | 0.0139276 | 0.1173540 | 7 | 0.0044473 | 0.0665605 | 9 | 4 | 0.0333333 | 0.1802581 | 5 | 0.0095238 | 0.0972168 |
| 381316210 | 210 | 381316 | 0.0000000 | condition_era group during day -365 through -1 days relative to index: Cerebrovascular accident | 3 | 1 | 0.0020877 | 0.0456912 | 2 | 0.0009528 | 0.0308607 | 3 | 1 | 0.0027855 | 0.0527780 | 2 | 0.0012706 | 0.0356348 | NA | NA | NA | NA | NA | NA | NA |
| 439777209 | 209 | 439777 | 0.0000000 | condition_era group any time prior through -1 days relative to index: Anemia | 59 | 15 | 0.0313152 | 0.1743504 | 44 | 0.0209624 | 0.1432924 | 40 | 9 | 0.0250696 | 0.1565549 | 31 | 0.0196950 | 0.1389943 | 19 | 6 | 0.0500000 | 0.2188588 | 13 | 0.0247619 | 0.1555469 |
| 439777210 | 210 | 439777 | 0.0000000 | condition_era group during day -365 through -1 days relative to index: Anemia | 5 | 2 | 0.0041754 | 0.0645494 | 3 | 0.0014293 | 0.0377874 | 3 | 1 | 0.0027855 | 0.0527780 | 2 | 0.0012706 | 0.0356348 | 2 | 1 | 0.0083333 | 0.0912871 | 1 | 0.0019048 | 0.0436436 |
| 440086209 | 209 | 440086 | 0.0000000 | condition_era group any time prior through -1 days relative to index: Child attention deficit disorder | 241 | 48 | 0.1002088 | 0.3005921 | 193 | 0.0919485 | 0.2890222 | 190 | 39 | 0.1086351 | 0.3116151 | 151 | 0.0959339 | 0.2945942 | 51 | 9 | 0.0750000 | 0.2644957 | 42 | 0.0800000 | 0.2715519 |
| 440448209 | 209 | 440448 | 0.0000000 | condition_era group any time prior through -1 days relative to index: Appendicitis | 116 | 23 | 0.0480167 | 0.2140251 | 93 | 0.0443068 | 0.2058249 | 83 | 12 | 0.0334262 | 0.1799976 | 71 | 0.0451080 | 0.2076070 | 33 | 11 | 0.0916667 | 0.2897647 | 22 | 0.0419048 | 0.2005626 |
| 705944409 | 409 | 705944 | 0.0000000 | drug_era group any time prior through -1 days relative to index: Methylphenidate | 62 | 12 | 0.0250522 | 0.1564470 | 50 | 0.0238209 | 0.1525271 | 52 | 9 | 0.0250696 | 0.1565549 | 43 | 0.0273189 | 0.1630629 | 10 | 3 | 0.0250000 | 0.1567796 | 7 | 0.0133333 | 0.1148071 |
| 708298409 | 409 | 708298 | 0.0000000 | drug_era group any time prior through -1 days relative to index: Midazolam | 23 | 5 | 0.0104384 | 0.1017402 | 18 | 0.0085755 | 0.0922281 | 20 | 5 | 0.0139276 | 0.1173540 | 15 | 0.0095299 | 0.0971856 | 3 | 0 | 0.0000000 | 0.0000000 | 3 | 0.0057143 | 0.0754485 |
| 708298410 | NA | NA | 0.0000000 | drug_era group during day -365 through -1 days relative to index: Midazolam | 1 | 0 | 0.0000000 | 0.0000000 | 1 | 0.0004764 | 0.0218270 | 1 | 0 | 0.0000000 | 0.0000000 | 1 | 0.0006353 | 0.0252056 | NA | NA | NA | NA | NA | NA | NA |
| 723013409 | 409 | 723013 | 0.0000000 | drug_era group any time prior through -1 days relative to index: Diazepam | 49 | 6 | 0.0125261 | 0.1113331 | 43 | 0.0204859 | 0.1416892 | 38 | 6 | 0.0167131 | 0.1283732 | 32 | 0.0203304 | 0.1411726 | 11 | 0 | 0.0000000 | 0.0000000 | 11 | 0.0209524 | 0.1433615 |
| 723013410 | NA | NA | 0.0000000 | drug_era group during day -365 through -1 days relative to index: Diazepam | 1 | 0 | 0.0000000 | 0.0000000 | 1 | 0.0004764 | 0.0218270 | 1 | 0 | 0.0000000 | 0.0000000 | 1 | 0.0006353 | 0.0252056 | NA | NA | NA | NA | NA | NA | NA |
| 738818409 | 409 | 738818 | 0.0000000 | drug_era group any time prior through -1 days relative to index: Doxylamine | 998 | 182 | 0.3799582 | 0.4858836 | 816 | 0.3887566 | 0.4875840 | 758 | 141 | 0.3927577 | 0.4890453 | 617 | 0.3919949 | 0.4883507 | 240 | 41 | 0.3416667 | 0.4762570 | 199 | 0.3790476 | 0.4856127 |
| 738818410 | 410 | 738818 | 0.0000000 | drug_era group during day -365 through -1 days relative to index: Doxylamine | 23 | 5 | 0.0104384 | 0.1017402 | 18 | 0.0085755 | 0.0922281 | 14 | 3 | 0.0083565 | 0.0911584 | 11 | 0.0069886 | 0.0833315 | 9 | 2 | 0.0166667 | 0.1285559 | 7 | 0.0133333 | 0.1148071 |
| 740275409 | 409 | 740275 | 0.0000000 | drug_era group any time prior through -1 days relative to index: Carbamazepine | 39 | 8 | 0.0167015 | 0.1282844 | 31 | 0.0147689 | 0.1206555 | 31 | 8 | 0.0222841 | 0.1478120 | 23 | 0.0146125 | 0.1200337 | 8 | 0 | 0.0000000 | 0.0000000 | 8 | 0.0152381 | 0.1226154 |
| 740275410 | 410 | 740275 | 0.0000000 | drug_era group during day -365 through -1 days relative to index: Carbamazepine | 2 | 1 | 0.0020877 | 0.0456912 | 1 | 0.0004764 | 0.0218270 | 2 | 1 | 0.0027855 | 0.0527780 | 1 | 0.0006353 | 0.0252056 | NA | NA | NA | NA | NA | NA | NA |
| 753626409 | 409 | 753626 | 0.0000000 | drug_era group any time prior through -1 days relative to index: Propofol | 24 | 5 | 0.0104384 | 0.1017402 | 19 | 0.0090519 | 0.0947326 | 20 | 5 | 0.0139276 | 0.1173540 | 15 | 0.0095299 | 0.0971856 | 4 | 0 | 0.0000000 | 0.0000000 | 4 | 0.0076190 | 0.0870369 |
| 753626410 | NA | NA | 0.0000000 | drug_era group during day -365 through -1 days relative to index: Propofol | 1 | 0 | 0.0000000 | 0.0000000 | 1 | 0.0004764 | 0.0218270 | 1 | 0 | 0.0000000 | 0.0000000 | 1 | 0.0006353 | 0.0252056 | NA | NA | NA | NA | NA | NA | NA |
| 782043409 | 409 | 782043 | 0.0000000 | drug_era group any time prior through -1 days relative to index: Isoflurane | 17 | 4 | 0.0083507 | 0.0910951 | 13 | 0.0061934 | 0.0784729 | 14 | 4 | 0.0111421 | 0.1051128 | 10 | 0.0063532 | 0.0794789 | 3 | 0 | 0.0000000 | 0.0000000 | 3 | 0.0057143 | 0.0754485 |
| 782043410 | NA | NA | 0.0000000 | drug_era group during day -365 through -1 days relative to index: Isoflurane | 1 | 0 | 0.0000000 | 0.0000000 | 1 | 0.0004764 | 0.0218270 | 1 | 0 | 0.0000000 | 0.0000000 | 1 | 0.0006353 | 0.0252056 | NA | NA | NA | NA | NA | NA | NA |
| 791967409 | NA | NA | 0.0000000 | drug_era group any time prior through -1 days relative to index: Lorazepam | 1 | 0 | 0.0000000 | 0.0000000 | 1 | 0.0004764 | 0.0218270 | NA | NA | NA | NA | NA | NA | NA | 1 | 0 | 0.0000000 | 0.0000000 | 1 | 0.0019048 | 0.0436436 |
| 914335409 | 409 | 914335 | 0.0000000 | drug_era group any time prior through -1 days relative to index: Atropine | 66 | 11 | 0.0229645 | 0.1499469 | 55 | 0.0262030 | 0.1597765 | 51 | 11 | 0.0306407 | 0.1725827 | 40 | 0.0254130 | 0.1574258 | 15 | 0 | 0.0000000 | 0.0000000 | 15 | 0.0285714 | 0.1667575 |
| 914335410 | 410 | 914335 | 0.0000000 | drug_era group during day -365 through -1 days relative to index: Atropine | 2 | 0 | 0.0000000 | 0.0000000 | 2 | 0.0009528 | 0.0308607 | 2 | 0 | 0.0000000 | 0.0000000 | 2 | 0.0012706 | 0.0356348 | NA | NA | NA | NA | NA | NA | NA |
| 920293409 | 409 | 920293 | 0.0000000 | drug_era group any time prior through -1 days relative to index: Nitrofurantoin | 361 | 74 | 0.1544885 | 0.3617943 | 287 | 0.1367318 | 0.3436458 | 267 | 57 | 0.1587744 | 0.3659756 | 210 | 0.1334180 | 0.3401340 | 94 | 17 | 0.1416667 | 0.3501700 | 77 | 0.1466667 | 0.3541107 |
| 920293410 | 410 | 920293 | 0.0000000 | drug_era group during day -365 through -1 days relative to index: Nitrofurantoin | 21 | 7 | 0.0146138 | 0.1201264 | 14 | 0.0066698 | 0.0814157 | 17 | 6 | 0.0167131 | 0.1283732 | 11 | 0.0069886 | 0.0833315 | 4 | 1 | 0.0083333 | 0.0912871 | 3 | 0.0057143 | 0.0754485 |
| 933724409 | 409 | 933724 | 0.0000000 | drug_era group any time prior through -1 days relative to index: Phenazopyridine | 361 | 74 | 0.1544885 | 0.3617943 | 287 | 0.1367318 | 0.3436458 | 267 | 57 | 0.1587744 | 0.3659756 | 210 | 0.1334180 | 0.3401340 | 94 | 17 | 0.1416667 | 0.3501700 | 77 | 0.1466667 | 0.3541107 |
| 933724410 | 410 | 933724 | 0.0000000 | drug_era group during day -365 through -1 days relative to index: Phenazopyridine | 21 | 7 | 0.0146138 | 0.1201264 | 14 | 0.0066698 | 0.0814157 | 17 | 6 | 0.0167131 | 0.1283732 | 11 | 0.0069886 | 0.0833315 | 4 | 1 | 0.0083333 | 0.0912871 | 3 | 0.0057143 | 0.0754485 |
| 967823409 | 409 | 967823 | 0.0000000 | drug_era group any time prior through -1 days relative to index: Sodium Chloride | 24 | 5 | 0.0104384 | 0.1017402 | 19 | 0.0090519 | 0.0947326 | 20 | 5 | 0.0139276 | 0.1173540 | 15 | 0.0095299 | 0.0971856 | 4 | 0 | 0.0000000 | 0.0000000 | 4 | 0.0076190 | 0.0870369 |
| 967823410 | NA | NA | 0.0000000 | drug_era group during day -365 through -1 days relative to index: Sodium Chloride | 1 | 0 | 0.0000000 | 0.0000000 | 1 | 0.0004764 | 0.0218270 | 1 | 0 | 0.0000000 | 0.0000000 | 1 | 0.0006353 | 0.0252056 | NA | NA | NA | NA | NA | NA | NA |
| 975125409 | 409 | 975125 | 0.0000000 | drug_era group any time prior through -1 days relative to index: Hydrocortisone | 98 | 11 | 0.0229645 | 0.1499469 | 87 | 0.0414483 | 0.1993722 | 69 | 6 | 0.0167131 | 0.1283732 | 63 | 0.0400254 | 0.1960811 | 29 | 5 | 0.0416667 | 0.2006642 | 24 | 0.0457143 | 0.2090640 |
| 975125410 | 410 | 975125 | 0.0000000 | drug_era group during day -365 through -1 days relative to index: Hydrocortisone | 3 | 1 | 0.0020877 | 0.0456912 | 2 | 0.0009528 | 0.0308607 | 2 | 0 | 0.0000000 | 0.0000000 | 2 | 0.0012706 | 0.0356348 | 1 | 1 | 0.0083333 | 0.0912871 | 0 | 0.0000000 | 0.0000000 |
| 1000560409 | 409 | 1000560 | 0.0000000 | drug_era group any time prior through -1 days relative to index: Ondansetron | 24 | 5 | 0.0104384 | 0.1017402 | 19 | 0.0090519 | 0.0947326 | 20 | 5 | 0.0139276 | 0.1173540 | 15 | 0.0095299 | 0.0971856 | 4 | 0 | 0.0000000 | 0.0000000 | 4 | 0.0076190 | 0.0870369 |
| 1000560410 | NA | NA | 0.0000000 | drug_era group during day -365 through -1 days relative to index: Ondansetron | 1 | 0 | 0.0000000 | 0.0000000 | 1 | 0.0004764 | 0.0218270 | 1 | 0 | 0.0000000 | 0.0000000 | 1 | 0.0006353 | 0.0252056 | NA | NA | NA | NA | NA | NA | NA |
| 1102527409 | 409 | 1102527 | 0.0000000 | drug_era group any time prior through -1 days relative to index: Meperidine | 198 | 40 | 0.0835073 | 0.2769367 | 158 | 0.0752739 | 0.2638957 | 145 | 29 | 0.0807799 | 0.2728772 | 116 | 0.0736976 | 0.2613611 | 53 | 11 | 0.0916667 | 0.2897647 | 42 | 0.0800000 | 0.2715519 |
| 1102527410 | 410 | 1102527 | 0.0000000 | drug_era group during day -365 through -1 days relative to index: Meperidine | 11 | 0 | 0.0000000 | 0.0000000 | 11 | 0.0052406 | 0.0722192 | 10 | 0 | 0.0000000 | 0.0000000 | 10 | 0.0063532 | 0.0794789 | 1 | 0 | 0.0000000 | 0.0000000 | 1 | 0.0019048 | 0.0436436 |
| 1107830409 | 409 | 1107830 | 0.0000000 | drug_era group any time prior through -1 days relative to index: Loratadine | 8 | 1 | 0.0020877 | 0.0456912 | 7 | 0.0033349 | 0.0576661 | 4 | 0 | 0.0000000 | 0.0000000 | 4 | 0.0025413 | 0.0503632 | 4 | 1 | 0.0083333 | 0.0912871 | 3 | 0.0057143 | 0.0754485 |
| 1110410409 | 409 | 1110410 | 0.0000000 | drug_era group any time prior through -1 days relative to index: Morphine | 24 | 5 | 0.0104384 | 0.1017402 | 19 | 0.0090519 | 0.0947326 | 20 | 5 | 0.0139276 | 0.1173540 | 15 | 0.0095299 | 0.0971856 | 4 | 0 | 0.0000000 | 0.0000000 | 4 | 0.0076190 | 0.0870369 |
| 1110410410 | NA | NA | 0.0000000 | drug_era group during day -365 through -1 days relative to index: Morphine | 1 | 0 | 0.0000000 | 0.0000000 | 1 | 0.0004764 | 0.0218270 | 1 | 0 | 0.0000000 | 0.0000000 | 1 | 0.0006353 | 0.0252056 | NA | NA | NA | NA | NA | NA | NA |
| 1112807409 | 409 | 1112807 | -0.0382128 | drug_era group any time prior through -1 days relative to index: Aspirin | 1878 | 328 | 0.6847599 | 0.4650972 | 1550 | 0.7384469 | 0.4395852 | 1414 | 250 | 0.6963788 | 0.4604628 | 1164 | 0.7395172 | 0.4390376 | 464 | 78 | 0.6500000 | 0.4789695 | 386 | 0.7352381 | 0.4416271 |
| 1112807410 | 410 | 1112807 | 0.0000000 | drug_era group during day -365 through -1 days relative to index: Aspirin | 9 | 0 | 0.0000000 | 0.0000000 | 9 | 0.0042878 | 0.0653560 | 8 | 0 | 0.0000000 | 0.0000000 | 8 | 0.0050826 | 0.0711335 | 1 | 0 | 0.0000000 | 0.0000000 | 1 | 0.0019048 | 0.0436436 |
| 1115008409 | 409 | 1115008 | 0.0000000 | drug_era group any time prior through -1 days relative to index: Naproxen | 286 | 59 | 0.1231733 | 0.3289796 | 227 | 0.1081467 | 0.3106397 | 205 | 39 | 0.1086351 | 0.3116151 | 166 | 0.1054638 | 0.3072477 | 81 | 20 | 0.1666667 | 0.3742406 | 61 | 0.1161905 | 0.3207588 |
| 1115008410 | 410 | 1115008 | 0.0000000 | drug_era group during day -365 through -1 days relative to index: Naproxen | 27 | 4 | 0.0083507 | 0.0910951 | 23 | 0.0109576 | 0.1041283 | 22 | 3 | 0.0083565 | 0.0911584 | 19 | 0.0120712 | 0.1092384 | 5 | 1 | 0.0083333 | 0.0912871 | 4 | 0.0076190 | 0.0870369 |
| 1119510409 | 409 | 1119510 | 0.0000000 | drug_era group any time prior through -1 days relative to index: Dextromethorphan | 998 | 182 | 0.3799582 | 0.4858836 | 816 | 0.3887566 | 0.4875840 | 758 | 141 | 0.3927577 | 0.4890453 | 617 | 0.3919949 | 0.4883507 | 240 | 41 | 0.3416667 | 0.4762570 | 199 | 0.3790476 | 0.4856127 |
| 1119510410 | 410 | 1119510 | 0.0000000 | drug_era group during day -365 through -1 days relative to index: Dextromethorphan | 23 | 5 | 0.0104384 | 0.1017402 | 18 | 0.0085755 | 0.0922281 | 14 | 3 | 0.0083565 | 0.0911584 | 11 | 0.0069886 | 0.0833315 | 9 | 2 | 0.0166667 | 0.1285559 | 7 | 0.0133333 | 0.1148071 |
| 1124957409 | 409 | 1124957 | 0.0000000 | drug_era group any time prior through -1 days relative to index: Oxycodone | 193 | 38 | 0.0793319 | 0.2705387 | 155 | 0.0738447 | 0.2615803 | 142 | 32 | 0.0891365 | 0.2853383 | 110 | 0.0698856 | 0.2550352 | 51 | 6 | 0.0500000 | 0.2188588 | 45 | 0.0857143 | 0.2802087 |
| 1124957410 | 410 | 1124957 | 0.0000000 | drug_era group during day -365 through -1 days relative to index: Oxycodone | 5 | 0 | 0.0000000 | 0.0000000 | 5 | 0.0023821 | 0.0487601 | 3 | 0 | 0.0000000 | 0.0000000 | 3 | 0.0019060 | 0.0436297 | 2 | 0 | 0.0000000 | 0.0000000 | 2 | 0.0038095 | 0.0616624 |
| 1125315409 | 409 | 1125315 | 0.0000000 | drug_era group any time prior through -1 days relative to index: Acetaminophen | 2512 | 467 | 0.9749478 | 0.1564470 | 2045 | 0.9742735 | 0.1583560 | 1887 | 348 | 0.9693593 | 0.1725827 | 1539 | 0.9777637 | 0.1474982 | 625 | 119 | 0.9916667 | 0.0912871 | 506 | 0.9638095 | 0.1869419 |
| 1125315410 | 410 | 1125315 | 0.0000000 | drug_era group during day -365 through -1 days relative to index: Acetaminophen | 187 | 28 | 0.0584551 | 0.2348473 | 159 | 0.0757504 | 0.2646613 | 134 | 20 | 0.0557103 | 0.2296815 | 114 | 0.0724269 | 0.2592759 | 53 | 8 | 0.0666667 | 0.2504897 | 45 | 0.0857143 | 0.2802087 |
| 1129625409 | 409 | 1129625 | 0.0000000 | drug_era group any time prior through -1 days relative to index: Diphenhydramine | 102 | 16 | 0.0334029 | 0.1798742 | 86 | 0.0409719 | 0.1982723 | 72 | 13 | 0.0362117 | 0.1870773 | 59 | 0.0374841 | 0.1900052 | 30 | 3 | 0.0250000 | 0.1567796 | 27 | 0.0514286 | 0.2210809 |
| 1137529409 | 409 | 1137529 | 0.0000000 | drug_era group any time prior through -1 days relative to index: salmeterol | 45 | 11 | 0.0229645 | 0.1499469 | 34 | 0.0161982 | 0.1262672 | 33 | 8 | 0.0222841 | 0.1478120 | 25 | 0.0158831 | 0.1250630 | 12 | 3 | 0.0250000 | 0.1567796 | 9 | 0.0171429 | 0.1299274 |
| 1137529410 | 410 | 1137529 | 0.0000000 | drug_era group during day -365 through -1 days relative to index: salmeterol | 3 | 0 | 0.0000000 | 0.0000000 | 3 | 0.0014293 | 0.0377874 | 2 | 0 | 0.0000000 | 0.0000000 | 2 | 0.0012706 | 0.0356348 | 1 | 0 | 0.0000000 | 0.0000000 | 1 | 0.0019048 | 0.0436436 |
| 1149196409 | 409 | 1149196 | 0.0000000 | drug_era group any time prior through -1 days relative to index: Cetirizine | 3 | 1 | 0.0020877 | 0.0456912 | 2 | 0.0009528 | 0.0308607 | 3 | 1 | 0.0027855 | 0.0527780 | 2 | 0.0012706 | 0.0356348 | NA | NA | NA | NA | NA | NA | NA |
| 1149380409 | 409 | 1149380 | 0.0000000 | drug_era group any time prior through -1 days relative to index: fluticasone | 138 | 24 | 0.0501044 | 0.2183884 | 114 | 0.0543116 | 0.2266855 | 99 | 19 | 0.0529248 | 0.2241958 | 80 | 0.0508259 | 0.2197119 | 39 | 5 | 0.0416667 | 0.2006642 | 34 | 0.0647619 | 0.2463400 |
| 1149380410 | 410 | 1149380 | 0.0000000 | drug_era group during day -365 through -1 days relative to index: fluticasone | 3 | 0 | 0.0000000 | 0.0000000 | 3 | 0.0014293 | 0.0377874 | 2 | 0 | 0.0000000 | 0.0000000 | 2 | 0.0012706 | 0.0356348 | 1 | 0 | 0.0000000 | 0.0000000 | 1 | 0.0019048 | 0.0436436 |
| 1150770409 | 409 | 1150770 | 0.0000000 | drug_era group any time prior through -1 days relative to index: Astemizole | 21 | 2 | 0.0041754 | 0.0645494 | 19 | 0.0090519 | 0.0947326 | 13 | 0 | 0.0000000 | 0.0000000 | 13 | 0.0082592 | 0.0905329 | 8 | 2 | 0.0166667 | 0.1285559 | 6 | 0.0114286 | 0.1063932 |
| 1150770410 | NA | NA | 0.0000000 | drug_era group during day -365 through -1 days relative to index: Astemizole | 1 | 1 | 0.0020877 | 0.0456912 | 0 | 0.0000000 | 0.0000000 | NA | NA | NA | NA | NA | NA | NA | 1 | 1 | 0.0083333 | 0.0912871 | 0 | 0.0000000 | 0.0000000 |
| 1150836409 | 409 | 1150836 | 0.0000000 | drug_era group any time prior through -1 days relative to index: Terfenadine | 7 | 1 | 0.0020877 | 0.0456912 | 6 | 0.0028585 | 0.0534012 | 6 | 1 | 0.0027855 | 0.0527780 | 5 | 0.0031766 | 0.0562898 | 1 | 0 | 0.0000000 | 0.0000000 | 1 | 0.0019048 | 0.0436436 |
| 1153428409 | 409 | 1153428 | 0.0000000 | drug_era group any time prior through -1 days relative to index: fexofenadine | 7 | 0 | 0.0000000 | 0.0000000 | 7 | 0.0033349 | 0.0576661 | 6 | 0 | 0.0000000 | 0.0000000 | 6 | 0.0038119 | 0.0616427 | 1 | 0 | 0.0000000 | 0.0000000 | 1 | 0.0019048 | 0.0436436 |
| 1154029409 | 409 | 1154029 | 0.0000000 | drug_era group any time prior through -1 days relative to index: Fentanyl | 4 | 1 | 0.0020877 | 0.0456912 | 3 | 0.0014293 | 0.0377874 | 3 | 1 | 0.0027855 | 0.0527780 | 2 | 0.0012706 | 0.0356348 | 1 | 0 | 0.0000000 | 0.0000000 | 1 | 0.0019048 | 0.0436436 |
| 1154029410 | NA | NA | 0.0000000 | drug_era group during day -365 through -1 days relative to index: Fentanyl | 1 | 0 | 0.0000000 | 0.0000000 | 1 | 0.0004764 | 0.0218270 | 1 | 0 | 0.0000000 | 0.0000000 | 1 | 0.0006353 | 0.0252056 | NA | NA | NA | NA | NA | NA | NA |
| 1154343409 | 409 | 1154343 | 0.0000000 | drug_era group any time prior through -1 days relative to index: Albuterol | 93 | 13 | 0.0271399 | 0.1626608 | 80 | 0.0381134 | 0.1915156 | 66 | 11 | 0.0306407 | 0.1725827 | 55 | 0.0349428 | 0.1836934 | 27 | 2 | 0.0166667 | 0.1285559 | 25 | 0.0476190 | 0.2131620 |
| 1174888409 | 409 | 1174888 | 0.0000000 | drug_era group any time prior through -1 days relative to index: Hydrocodone | 175 | 26 | 0.0542797 | 0.2268058 | 149 | 0.0709862 | 0.2568630 | 138 | 21 | 0.0584958 | 0.2350062 | 117 | 0.0743329 | 0.2623953 | 37 | 5 | 0.0416667 | 0.2006642 | 32 | 0.0609524 | 0.2394711 |
| 1174888410 | 410 | 1174888 | 0.0000000 | drug_era group during day -365 through -1 days relative to index: Hydrocodone | 3 | 1 | 0.0020877 | 0.0456912 | 2 | 0.0009528 | 0.0308607 | 2 | 1 | 0.0027855 | 0.0527780 | 1 | 0.0006353 | 0.0252056 | 1 | 0 | 0.0000000 | 0.0000000 | 1 | 0.0019048 | 0.0436436 |
| 1177480409 | 409 | 1177480 | 0.0000000 | drug_era group any time prior through -1 days relative to index: Ibuprofen | 780 | 140 | 0.2922756 | 0.4552838 | 640 | 0.3049071 | 0.4604778 | 595 | 110 | 0.3064067 | 0.4616441 | 485 | 0.3081321 | 0.4618682 | 185 | 30 | 0.2500000 | 0.4348283 | 155 | 0.2952381 | 0.4565848 |
| 1177480410 | 410 | 1177480 | 0.0000000 | drug_era group during day -365 through -1 days relative to index: Ibuprofen | 35 | 7 | 0.0146138 | 0.1201264 | 28 | 0.0133397 | 0.1147520 | 24 | 4 | 0.0111421 | 0.1051128 | 20 | 0.0127065 | 0.1120402 | 11 | 3 | 0.0250000 | 0.1567796 | 8 | 0.0152381 | 0.1226154 |
| 1192710409 | 409 | 1192710 | 0.0000000 | drug_era group any time prior through -1 days relative to index: Chlorpheniramine | 67 | 12 | 0.0250522 | 0.1564470 | 55 | 0.0262030 | 0.1597765 | 53 | 9 | 0.0250696 | 0.1565549 | 44 | 0.0279543 | 0.1648942 | 14 | 3 | 0.0250000 | 0.1567796 | 11 | 0.0209524 | 0.1433615 |
| 1305058409 | 409 | 1305058 | 0.0000000 | drug_era group any time prior through -1 days relative to index: Methotrexate | 3 | 1 | 0.0020877 | 0.0456912 | 2 | 0.0009528 | 0.0308607 | 1 | 0 | 0.0000000 | 0.0000000 | 1 | 0.0006353 | 0.0252056 | 2 | 1 | 0.0083333 | 0.0912871 | 1 | 0.0019048 | 0.0436436 |
| 1305058410 | NA | NA | 0.0000000 | drug_era group during day -365 through -1 days relative to index: Methotrexate | 1 | 0 | 0.0000000 | 0.0000000 | 1 | 0.0004764 | 0.0218270 | NA | NA | NA | NA | NA | NA | NA | 1 | 0 | 0.0000000 | 0.0000000 | 1 | 0.0019048 | 0.0436436 |
| 1308738409 | 409 | 1308738 | 0.0000000 | drug_era group any time prior through -1 days relative to index: Vitamin B 12 | 10 | 1 | 0.0020877 | 0.0456912 | 9 | 0.0042878 | 0.0653560 | 6 | 0 | 0.0000000 | 0.0000000 | 6 | 0.0038119 | 0.0616427 | 4 | 1 | 0.0083333 | 0.0912871 | 3 | 0.0057143 | 0.0754485 |
| 1309944409 | 409 | 1309944 | 0.0000000 | drug_era group any time prior through -1 days relative to index: Amiodarone | 54 | 11 | 0.0229645 | 0.1499469 | 43 | 0.0204859 | 0.1416892 | 44 | 11 | 0.0306407 | 0.1725827 | 33 | 0.0209657 | 0.1433150 | 10 | 0 | 0.0000000 | 0.0000000 | 10 | 0.0190476 | 0.1368228 |
| 1309944410 | 410 | 1309944 | 0.0000000 | drug_era group during day -365 through -1 days relative to index: Amiodarone | 2 | 0 | 0.0000000 | 0.0000000 | 2 | 0.0009528 | 0.0308607 | 2 | 0 | 0.0000000 | 0.0000000 | 2 | 0.0012706 | 0.0356348 | NA | NA | NA | NA | NA | NA | NA |
| 1322184409 | 409 | 1322184 | 0.0000000 | drug_era group any time prior through -1 days relative to index: clopidogrel | 33 | 6 | 0.0125261 | 0.1113331 | 27 | 0.0128633 | 0.1127114 | 26 | 4 | 0.0111421 | 0.1051128 | 22 | 0.0139771 | 0.1174331 | 7 | 2 | 0.0166667 | 0.1285559 | 5 | 0.0095238 | 0.0972168 |
| 1322184410 | 410 | 1322184 | 0.0000000 | drug_era group during day -365 through -1 days relative to index: clopidogrel | 13 | 2 | 0.0041754 | 0.0645494 | 11 | 0.0052406 | 0.0722192 | 11 | 2 | 0.0055710 | 0.0745350 | 9 | 0.0057179 | 0.0754244 | 2 | 0 | 0.0000000 | 0.0000000 | 2 | 0.0038095 | 0.0616624 |
| 1332418409 | 409 | 1332418 | 0.0000000 | drug_era group any time prior through -1 days relative to index: Amlodipine | 29 | 6 | 0.0125261 | 0.1113331 | 23 | 0.0109576 | 0.1041283 | 25 | 5 | 0.0139276 | 0.1173540 | 20 | 0.0127065 | 0.1120402 | 4 | 1 | 0.0083333 | 0.0912871 | 3 | 0.0057143 | 0.0754485 |
| 1332418410 | 410 | 1332418 | 0.0000000 | drug_era group during day -365 through -1 days relative to index: Amlodipine | 5 | 1 | 0.0020877 | 0.0456912 | 4 | 0.0019057 | 0.0436228 | 4 | 1 | 0.0027855 | 0.0527780 | 3 | 0.0019060 | 0.0436297 | 1 | 0 | 0.0000000 | 0.0000000 | 1 | 0.0019048 | 0.0436436 |
| 1343916409 | 409 | 1343916 | 0.0000000 | drug_era group any time prior through -1 days relative to index: Epinephrine | 90 | 14 | 0.0292276 | 0.1686199 | 76 | 0.0362077 | 0.1868512 | 69 | 13 | 0.0362117 | 0.1870773 | 56 | 0.0355781 | 0.1852948 | 21 | 1 | 0.0083333 | 0.0912871 | 20 | 0.0380952 | 0.1916088 |
| 1343916410 | 410 | 1343916 | 0.0000000 | drug_era group during day -365 through -1 days relative to index: Epinephrine | 2 | 0 | 0.0000000 | 0.0000000 | 2 | 0.0009528 | 0.0308607 | 2 | 0 | 0.0000000 | 0.0000000 | 2 | 0.0012706 | 0.0356348 | NA | NA | NA | NA | NA | NA | NA |
| 1347450409 | 409 | 1347450 | 0.0000000 | drug_era group any time prior through -1 days relative to index: alteplase | 13 | 6 | 0.0125261 | 0.1113331 | 7 | 0.0033349 | 0.0576661 | 7 | 2 | 0.0055710 | 0.0745350 | 5 | 0.0031766 | 0.0562898 | 6 | 4 | 0.0333333 | 0.1802581 | 2 | 0.0038095 | 0.0616624 |
| 1347450410 | 410 | 1347450 | 0.0000000 | drug_era group during day -365 through -1 days relative to index: alteplase | 2 | 0 | 0.0000000 | 0.0000000 | 2 | 0.0009528 | 0.0308607 | 2 | 0 | 0.0000000 | 0.0000000 | 2 | 0.0012706 | 0.0356348 | NA | NA | NA | NA | NA | NA | NA |
| 1361711409 | 409 | 1361711 | 0.0000000 | drug_era group any time prior through -1 days relative to index: Nitroglycerin | 55 | 10 | 0.0208768 | 0.1431214 | 45 | 0.0214388 | 0.1448764 | 44 | 8 | 0.0222841 | 0.1478120 | 36 | 0.0228717 | 0.1495418 | 11 | 2 | 0.0166667 | 0.1285559 | 9 | 0.0171429 | 0.1299274 |
| 1361711410 | 410 | 1361711 | 0.0000000 | drug_era group during day -365 through -1 days relative to index: Nitroglycerin | 20 | 3 | 0.0062630 | 0.0789737 | 17 | 0.0080991 | 0.0896511 | 14 | 2 | 0.0055710 | 0.0745350 | 12 | 0.0076239 | 0.0870090 | 6 | 1 | 0.0083333 | 0.0912871 | 5 | 0.0095238 | 0.0972168 |
| 1367571409 | 409 | 1367571 | 0.0000000 | drug_era group any time prior through -1 days relative to index: heparin | 24 | 5 | 0.0104384 | 0.1017402 | 19 | 0.0090519 | 0.0947326 | 20 | 5 | 0.0139276 | 0.1173540 | 15 | 0.0095299 | 0.0971856 | 4 | 0 | 0.0000000 | 0.0000000 | 4 | 0.0076190 | 0.0870369 |
| 1367571410 | NA | NA | 0.0000000 | drug_era group during day -365 through -1 days relative to index: heparin | 1 | 0 | 0.0000000 | 0.0000000 | 1 | 0.0004764 | 0.0218270 | 1 | 0 | 0.0000000 | 0.0000000 | 1 | 0.0006353 | 0.0252056 | NA | NA | NA | NA | NA | NA | NA |
| 1396131409 | 409 | 1396131 | 0.0000000 | drug_era group any time prior through -1 days relative to index: ferrous sulfate | 2 | 0 | 0.0000000 | 0.0000000 | 2 | 0.0009528 | 0.0308607 | 2 | 0 | 0.0000000 | 0.0000000 | 2 | 0.0012706 | 0.0356348 | NA | NA | NA | NA | NA | NA | NA |
| 1500211409 | 409 | 1500211 | 0.0000000 | drug_era group any time prior through -1 days relative to index: Medroxyprogesterone | 38 | 5 | 0.0104384 | 0.1017402 | 33 | 0.0157218 | 0.1244266 | 30 | 3 | 0.0083565 | 0.0911584 | 27 | 0.0171537 | 0.1298854 | 8 | 2 | 0.0166667 | 0.1285559 | 6 | 0.0114286 | 0.1063932 |
| 1503184409 | 409 | 1503184 | 0.0000000 | drug_era group any time prior through -1 days relative to index: Mestranol | 571 | 100 | 0.2087683 | 0.4068534 | 471 | 0.2243926 | 0.4172811 | 426 | 72 | 0.2005571 | 0.4009761 | 354 | 0.2249047 | 0.4176522 | 145 | 28 | 0.2333333 | 0.4247260 | 117 | 0.2228571 | 0.4165601 |
| 1512674409 | 409 | 1512674 | 0.0000000 | drug_era group any time prior through -1 days relative to index: drospirenone | 5 | 4 | 0.0083507 | 0.0910951 | 1 | 0.0004764 | 0.0218270 | 5 | 4 | 0.0111421 | 0.1051128 | 1 | 0.0006353 | 0.0252056 | NA | NA | NA | NA | NA | NA | NA |
| 1515774409 | 409 | 1515774 | 0.0000000 | drug_era group any time prior through -1 days relative to index: norgestimate | 227 | 39 | 0.0814196 | 0.2737644 | 188 | 0.0895665 | 0.2856277 | 171 | 29 | 0.0807799 | 0.2728772 | 142 | 0.0902160 | 0.2865820 | 56 | 10 | 0.0833333 | 0.2775443 | 46 | 0.0876190 | 0.2830097 |
| 1519936409 | 409 | 1519936 | 0.0000000 | drug_era group any time prior through -1 days relative to index: Etonogestrel | 2 | 0 | 0.0000000 | 0.0000000 | 2 | 0.0009528 | 0.0308607 | 1 | 0 | 0.0000000 | 0.0000000 | 1 | 0.0006353 | 0.0252056 | 1 | 0 | 0.0000000 | 0.0000000 | 1 | 0.0019048 | 0.0436436 |
| 1521369409 | 409 | 1521369 | 0.0000000 | drug_era group any time prior through -1 days relative to index: Norethindrone | 585 | 105 | 0.2192067 | 0.4141415 | 480 | 0.2286803 | 0.4200830 | 435 | 75 | 0.2089136 | 0.4071000 | 360 | 0.2287166 | 0.4201398 | 150 | 30 | 0.2500000 | 0.4348283 | 120 | 0.2285714 | 0.4203130 |
| 1521369410 | NA | NA | 0.0000000 | drug_era group during day -365 through -1 days relative to index: Norethindrone | 1 | 0 | 0.0000000 | 0.0000000 | 1 | 0.0004764 | 0.0218270 | 1 | 0 | 0.0000000 | 0.0000000 | 1 | 0.0006353 | 0.0252056 | NA | NA | NA | NA | NA | NA | NA |
| 1539403409 | 409 | 1539403 | 0.0000000 | drug_era group any time prior through -1 days relative to index: Simvastatin | 37 | 7 | 0.0146138 | 0.1201264 | 30 | 0.0142925 | 0.1187222 | 30 | 6 | 0.0167131 | 0.1283732 | 24 | 0.0152478 | 0.1225758 | 7 | 1 | 0.0083333 | 0.0912871 | 6 | 0.0114286 | 0.1063932 |
| 1539403410 | 410 | 1539403 | 0.0000000 | drug_era group during day -365 through -1 days relative to index: Simvastatin | 5 | 1 | 0.0020877 | 0.0456912 | 4 | 0.0019057 | 0.0436228 | 4 | 1 | 0.0027855 | 0.0527780 | 3 | 0.0019060 | 0.0436297 | 1 | 0 | 0.0000000 | 0.0000000 | 1 | 0.0019048 | 0.0436436 |
| 1545958409 | 409 | 1545958 | 0.0000000 | drug_era group any time prior through -1 days relative to index: atorvastatin | 2 | 1 | 0.0020877 | 0.0456912 | 1 | 0.0004764 | 0.0218270 | 2 | 1 | 0.0027855 | 0.0527780 | 1 | 0.0006353 | 0.0252056 | NA | NA | NA | NA | NA | NA | NA |
| 1549786409 | 409 | 1549786 | 0.0000000 | drug_era group any time prior through -1 days relative to index: Ethinyl Estradiol | 236 | 42 | 0.0876827 | 0.2831285 | 194 | 0.0924250 | 0.2896939 | 178 | 31 | 0.0863510 | 0.2812736 | 147 | 0.0933926 | 0.2910743 | 58 | 11 | 0.0916667 | 0.2897647 | 47 | 0.0895238 | 0.2857706 |
| 1551099409 | 409 | 1551099 | 0.0000000 | drug_era group any time prior through -1 days relative to index: Prednisone | 110 | 16 | 0.0334029 | 0.1798742 | 94 | 0.0447832 | 0.2068770 | 84 | 13 | 0.0362117 | 0.1870773 | 71 | 0.0451080 | 0.2076070 | 26 | 3 | 0.0250000 | 0.1567796 | 23 | 0.0438095 | 0.2048663 |
| 1551099410 | NA | NA | 0.0000000 | drug_era group during day -365 through -1 days relative to index: Prednisone | 1 | 0 | 0.0000000 | 0.0000000 | 1 | 0.0004764 | 0.0218270 | 1 | 0 | 0.0000000 | 0.0000000 | 1 | 0.0006353 | 0.0252056 | NA | NA | NA | NA | NA | NA | NA |
| 1589505409 | 409 | 1589505 | 0.0000000 | drug_era group any time prior through -1 days relative to index: Levonorgestrel | 28 | 7 | 0.0146138 | 0.1201264 | 21 | 0.0100048 | 0.0995459 | 18 | 4 | 0.0111421 | 0.1051128 | 14 | 0.0088945 | 0.0939203 | 10 | 3 | 0.0250000 | 0.1567796 | 7 | 0.0133333 | 0.1148071 |
| 1595799409 | 409 | 1595799 | 0.0000000 | drug_era group any time prior through -1 days relative to index: Ferrous fumarate | 43 | 15 | 0.0313152 | 0.1743504 | 28 | 0.0133397 | 0.1147520 | 31 | 11 | 0.0306407 | 0.1725827 | 20 | 0.0127065 | 0.1120402 | 12 | 4 | 0.0333333 | 0.1802581 | 8 | 0.0152381 | 0.1226154 |
| 1713332409 | 409 | 1713332 | 0.0000000 | drug_era group any time prior through -1 days relative to index: Amoxicillin | 1673 | 308 | 0.6430063 | 0.4796138 | 1365 | 0.6503097 | 0.4769857 | 1240 | 229 | 0.6378830 | 0.4812832 | 1011 | 0.6423126 | 0.4794718 | 433 | 79 | 0.6583333 | 0.4762570 | 354 | 0.6742857 | 0.4690881 |
| 1713332410 | 410 | 1713332 | 0.0000000 | drug_era group during day -365 through -1 days relative to index: Amoxicillin | 66 | 13 | 0.0271399 | 0.1626608 | 53 | 0.0252501 | 0.1569213 | 48 | 11 | 0.0306407 | 0.1725827 | 37 | 0.0235070 | 0.1515553 | 18 | 2 | 0.0166667 | 0.1285559 | 16 | 0.0304762 | 0.1720575 |
| 1717327409 | 409 | 1717327 | -0.0484324 | drug_era group any time prior through -1 days relative to index: Ampicillin | 419 | 74 | 0.1544885 | 0.3617943 | 345 | 0.1643640 | 0.3706938 | 328 | 53 | 0.1476323 | 0.3552302 | 275 | 0.1747141 | 0.3798431 | 91 | 21 | 0.1750000 | 0.3815603 | 70 | 0.1333333 | 0.3402588 |
| 1728416409 | 409 | 1728416 | -0.2160582 | drug_era group any time prior through -1 days relative to index: Penicillin G | 823 | 127 | 0.2651357 | 0.4418669 | 696 | 0.3315865 | 0.4708954 | 619 | 97 | 0.2701950 | 0.4446802 | 522 | 0.3316391 | 0.4709517 | 204 | 30 | 0.2500000 | 0.4348283 | 174 | 0.3314286 | 0.4711757 |
| 1728416410 | NA | NA | 0.0000000 | drug_era group during day -365 through -1 days relative to index: Penicillin G | 1 | 0 | 0.0000000 | 0.0000000 | 1 | 0.0004764 | 0.0218270 | 1 | 0 | 0.0000000 | 0.0000000 | 1 | 0.0006353 | 0.0252056 | NA | NA | NA | NA | NA | NA | NA |
| 1729720409 | 409 | 1729720 | 0.0000000 | drug_era group any time prior through -1 days relative to index: Penicillin V | 1465 | 281 | 0.5866388 | 0.4929513 | 1184 | 0.5640781 | 0.4959952 | 1099 | 211 | 0.5877437 | 0.4929278 | 888 | 0.5641677 | 0.4960230 | 366 | 70 | 0.5833333 | 0.4950738 | 296 | 0.5638095 | 0.4963846 |
| 1729720410 | 410 | 1729720 | 0.0000000 | drug_era group during day -365 through -1 days relative to index: Penicillin V | 22 | 7 | 0.0146138 | 0.1201264 | 15 | 0.0071463 | 0.0842530 | 21 | 7 | 0.0194986 | 0.1384623 | 14 | 0.0088945 | 0.0939203 | 1 | 0 | 0.0000000 | 0.0000000 | 1 | 0.0019048 | 0.0436436 |
| 1738521409 | 409 | 1738521 | 0.0000000 | drug_era group any time prior through -1 days relative to index: Doxycycline | 433 | 84 | 0.1753653 | 0.3806769 | 349 | 0.1662697 | 0.3724112 | 327 | 60 | 0.1671309 | 0.3736134 | 267 | 0.1696315 | 0.3754280 | 106 | 24 | 0.2000000 | 0.4016772 | 82 | 0.1561905 | 0.3633821 |
| 1738521410 | 410 | 1738521 | 0.0000000 | drug_era group during day -365 through -1 days relative to index: Doxycycline | 2 | 0 | 0.0000000 | 0.0000000 | 2 | 0.0009528 | 0.0308607 | 2 | 0 | 0.0000000 | 0.0000000 | 2 | 0.0012706 | 0.0356348 | NA | NA | NA | NA | NA | NA | NA |
| 1741122409 | 409 | 1741122 | 0.0000000 | drug_era group any time prior through -1 days relative to index: tazobactam | 24 | 5 | 0.0104384 | 0.1017402 | 19 | 0.0090519 | 0.0947326 | 20 | 5 | 0.0139276 | 0.1173540 | 15 | 0.0095299 | 0.0971856 | 4 | 0 | 0.0000000 | 0.0000000 | 4 | 0.0076190 | 0.0870369 |
| 1741122410 | NA | NA | 0.0000000 | drug_era group during day -365 through -1 days relative to index: tazobactam | 1 | 0 | 0.0000000 | 0.0000000 | 1 | 0.0004764 | 0.0218270 | 1 | 0 | 0.0000000 | 0.0000000 | 1 | 0.0006353 | 0.0252056 | NA | NA | NA | NA | NA | NA | NA |
| 1746114409 | 409 | 1746114 | 0.0000000 | drug_era group any time prior through -1 days relative to index: Piperacillin | 24 | 5 | 0.0104384 | 0.1017402 | 19 | 0.0090519 | 0.0947326 | 20 | 5 | 0.0139276 | 0.1173540 | 15 | 0.0095299 | 0.0971856 | 4 | 0 | 0.0000000 | 0.0000000 | 4 | 0.0076190 | 0.0870369 |
| 1746114410 | NA | NA | 0.0000000 | drug_era group during day -365 through -1 days relative to index: Piperacillin | 1 | 0 | 0.0000000 | 0.0000000 | 1 | 0.0004764 | 0.0218270 | 1 | 0 | 0.0000000 | 0.0000000 | 1 | 0.0006353 | 0.0252056 | NA | NA | NA | NA | NA | NA | NA |
| 1759842409 | 409 | 1759842 | 0.0000000 | drug_era group any time prior through -1 days relative to index: Clavulanate | 1592 | 291 | 0.6075157 | 0.4888141 | 1301 | 0.6198190 | 0.4855468 | 1181 | 215 | 0.5988858 | 0.4908081 | 966 | 0.6137230 | 0.4870501 | 411 | 76 | 0.6333333 | 0.4839149 | 335 | 0.6380952 | 0.4810098 |
| 1759842410 | 410 | 1759842 | 0.0000000 | drug_era group during day -365 through -1 days relative to index: Clavulanate | 58 | 13 | 0.0271399 | 0.1626608 | 45 | 0.0214388 | 0.1448764 | 42 | 11 | 0.0306407 | 0.1725827 | 31 | 0.0196950 | 0.1389943 | 16 | 2 | 0.0166667 | 0.1285559 | 14 | 0.0266667 | 0.1612609 |
| 1768849409 | 409 | 1768849 | 0.0085804 | drug_era group any time prior through -1 days relative to index: Cefaclor | 105 | 28 | 0.0584551 | 0.2348473 | 77 | 0.0366841 | 0.1880299 | 82 | 24 | 0.0668524 | 0.2501147 | 58 | 0.0368488 | 0.1884503 | 23 | 4 | 0.0333333 | 0.1802581 | 19 | 0.0361905 | 0.1869419 |
| 1768849410 | NA | NA | 0.0000000 | drug_era group during day -365 through -1 days relative to index: Cefaclor | 1 | 0 | 0.0000000 | 0.0000000 | 1 | 0.0004764 | 0.0218270 | 1 | 0 | 0.0000000 | 0.0000000 | 1 | 0.0006353 | 0.0252056 | NA | NA | NA | NA | NA | NA | NA |
| 1778162409 | 409 | 1778162 | 0.0000000 | drug_era group any time prior through -1 days relative to index: Cefuroxime | 55 | 12 | 0.0250522 | 0.1564470 | 43 | 0.0204859 | 0.1416892 | 38 | 9 | 0.0250696 | 0.1565549 | 29 | 0.0184244 | 0.1345230 | 17 | 3 | 0.0250000 | 0.1567796 | 14 | 0.0266667 | 0.1612609 |
| 1778162410 | 410 | 1778162 | 0.0000000 | drug_era group during day -365 through -1 days relative to index: Cefuroxime | 1 | 0 | 0.0000000 | 0.0000000 | 1 | 0.0004764 | 0.0218270 | 1 | 0 | 0.0000000 | 0.0000000 | 1 | 0.0006353 | 0.0252056 | NA | NA | NA | NA | NA | NA | NA |
| 4001336209 | 209 | 4001336 | 0.0000000 | condition_era group any time prior through -1 days relative to index: Concussion injury of brain | 776 | 145 | 0.3027140 | 0.4599128 | 631 | 0.3006193 | 0.4586366 | 600 | 115 | 0.3203343 | 0.4672562 | 485 | 0.3081321 | 0.4618682 | 176 | 30 | 0.2500000 | 0.4348283 | 146 | 0.2780952 | 0.4484879 |
| 4001336210 | 210 | 4001336 | 0.0000000 | condition_era group during day -365 through -1 days relative to index: Concussion injury of brain | 27 | 4 | 0.0083507 | 0.0910951 | 23 | 0.0109576 | 0.1041283 | 19 | 2 | 0.0055710 | 0.0745350 | 17 | 0.0108005 | 0.1033956 | 8 | 2 | 0.0166667 | 0.1285559 | 6 | 0.0114286 | 0.1063932 |
| 4027663209 | 209 | 4027663 | 1.2459687 | condition_era group any time prior through -1 days relative to index: Peptic ulcer | 780 | 266 | 0.5553236 | 0.4974494 | 514 | 0.2448785 | 0.4301176 | 576 | 202 | 0.5626741 | 0.4967487 | 374 | 0.2376112 | 0.4257549 | 204 | 64 | 0.5333333 | 0.5009794 | 140 | 0.2666667 | 0.4426384 |
| 4029498209 | 209 | 4029498 | 0.0000000 | condition_era group any time prior through -1 days relative to index: Seizure disorder | 65 | 13 | 0.0271399 | 0.1626608 | 52 | 0.0247737 | 0.1554718 | 54 | 13 | 0.0362117 | 0.1870773 | 41 | 0.0260483 | 0.1593295 | 11 | 0 | 0.0000000 | 0.0000000 | 11 | 0.0209524 | 0.1433615 |
| 4029498210 | 210 | 4029498 | 0.0000000 | condition_era group during day -365 through -1 days relative to index: Seizure disorder | 2 | 0 | 0.0000000 | 0.0000000 | 2 | 0.0009528 | 0.0308607 | 2 | 0 | 0.0000000 | 0.0000000 | 2 | 0.0012706 | 0.0356348 | NA | NA | NA | NA | NA | NA | NA |
| 4035415209 | 209 | 4035415 | 0.0000000 | condition_era group any time prior through -1 days relative to index: Tear of meniscus of knee | 54 | 8 | 0.0167015 | 0.1282844 | 46 | 0.0219152 | 0.1464416 | 41 | 6 | 0.0167131 | 0.1283732 | 35 | 0.0222363 | 0.1474982 | 13 | 2 | 0.0166667 | 0.1285559 | 11 | 0.0209524 | 0.1433615 |
| 4035415210 | 210 | 4035415 | 0.0000000 | condition_era group during day -365 through -1 days relative to index: Tear of meniscus of knee | 4 | 0 | 0.0000000 | 0.0000000 | 4 | 0.0019057 | 0.0436228 | 2 | 0 | 0.0000000 | 0.0000000 | 2 | 0.0012706 | 0.0356348 | 2 | 0 | 0.0000000 | 0.0000000 | 2 | 0.0038095 | 0.0616624 |
| 4048171209 | 209 | 4048171 | 0.0000000 | condition_era group any time prior through -1 days relative to index: Perennial allergic rhinitis with seasonal variation | 75 | 14 | 0.0292276 | 0.1686199 | 61 | 0.0290615 | 0.1680189 | 57 | 11 | 0.0306407 | 0.1725827 | 46 | 0.0292249 | 0.1684899 | 18 | 3 | 0.0250000 | 0.1567796 | 15 | 0.0285714 | 0.1667575 |
| 4048171210 | 210 | 4048171 | 0.0000000 | condition_era group during day -365 through -1 days relative to index: Perennial allergic rhinitis with seasonal variation | 3 | 1 | 0.0020877 | 0.0456912 | 2 | 0.0009528 | 0.0308607 | 3 | 1 | 0.0027855 | 0.0527780 | 2 | 0.0012706 | 0.0356348 | NA | NA | NA | NA | NA | NA | NA |
| 4048695209 | 209 | 4048695 | 0.0000000 | condition_era group any time prior through -1 days relative to index: Fracture of vertebral column without spinal cord injury | 11 | 3 | 0.0062630 | 0.0789737 | 8 | 0.0038113 | 0.0616330 | 9 | 3 | 0.0083565 | 0.0911584 | 6 | 0.0038119 | 0.0616427 | 2 | 0 | 0.0000000 | 0.0000000 | 2 | 0.0038095 | 0.0616624 |
| 4051466209 | 209 | 4051466 | 0.0000000 | condition_era group any time prior through -1 days relative to index: Childhood asthma | 88 | 13 | 0.0271399 | 0.1626608 | 75 | 0.0357313 | 0.1856637 | 61 | 11 | 0.0306407 | 0.1725827 | 50 | 0.0317662 | 0.1754328 | 27 | 2 | 0.0166667 | 0.1285559 | 25 | 0.0476190 | 0.2131620 |
| 4056621209 | 209 | 4056621 | 0.0000000 | condition_era group any time prior through -1 days relative to index: Recurrent urinary tract infection | 20 | 6 | 0.0125261 | 0.1113331 | 14 | 0.0066698 | 0.0814157 | 16 | 5 | 0.0139276 | 0.1173540 | 11 | 0.0069886 | 0.0833315 | 4 | 1 | 0.0083333 | 0.0912871 | 3 | 0.0057143 | 0.0754485 |
| 4056621210 | 210 | 4056621 | 0.0000000 | condition_era group during day -365 through -1 days relative to index: Recurrent urinary tract infection | 2 | 0 | 0.0000000 | 0.0000000 | 2 | 0.0009528 | 0.0308607 | 2 | 0 | 0.0000000 | 0.0000000 | 2 | 0.0012706 | 0.0356348 | NA | NA | NA | NA | NA | NA | NA |
| 4059173209 | 209 | 4059173 | 0.0000000 | condition_era group any time prior through -1 days relative to index: Fracture of ankle | 296 | 52 | 0.1085595 | 0.3114110 | 244 | 0.1162458 | 0.3205959 | 222 | 40 | 0.1114206 | 0.3150914 | 182 | 0.1156290 | 0.3198811 | 74 | 12 | 0.1000000 | 0.3012579 | 62 | 0.1180952 | 0.3230287 |
| 4059173210 | 210 | 4059173 | 0.0000000 | condition_era group during day -365 through -1 days relative to index: Fracture of ankle | 2 | 0 | 0.0000000 | 0.0000000 | 2 | 0.0009528 | 0.0308607 | 1 | 0 | 0.0000000 | 0.0000000 | 1 | 0.0006353 | 0.0252056 | 1 | 0 | 0.0000000 | 0.0000000 | 1 | 0.0019048 | 0.0436436 |
| 4066995209 | 209 | 4066995 | 0.0000000 | condition_era group any time prior through -1 days relative to index: Fracture of vertebral column with spinal cord injury | 3 | 0 | 0.0000000 | 0.0000000 | 3 | 0.0014293 | 0.0377874 | 2 | 0 | 0.0000000 | 0.0000000 | 2 | 0.0012706 | 0.0356348 | 1 | 0 | 0.0000000 | 0.0000000 | 1 | 0.0019048 | 0.0436436 |
| 4084167209 | 209 | 4084167 | 0.0000000 | condition_era group any time prior through -1 days relative to index: Acute allergic reaction | 107 | 15 | 0.0313152 | 0.1743504 | 92 | 0.0438304 | 0.2047664 | 81 | 12 | 0.0334262 | 0.1799976 | 69 | 0.0438374 | 0.2047982 | 26 | 3 | 0.0250000 | 0.1567796 | 23 | 0.0438095 | 0.2048663 |
| 4084167210 | NA | NA | 0.0000000 | condition_era group during day -365 through -1 days relative to index: Acute allergic reaction | 1 | 0 | 0.0000000 | 0.0000000 | 1 | 0.0004764 | 0.0218270 | 1 | 0 | 0.0000000 | 0.0000000 | 1 | 0.0006353 | 0.0252056 | NA | NA | NA | NA | NA | NA | NA |
| 4094814209 | 209 | 4094814 | 0.0000000 | condition_era group any time prior through -1 days relative to index: Bullet wound | 26 | 6 | 0.0125261 | 0.1113331 | 20 | 0.0095283 | 0.0971702 | 14 | 3 | 0.0083565 | 0.0911584 | 11 | 0.0069886 | 0.0833315 | 12 | 3 | 0.0250000 | 0.1567796 | 9 | 0.0171429 | 0.1299274 |
| 4109685209 | 209 | 4109685 | 0.0000000 | condition_era group any time prior through -1 days relative to index: Laceration of foot | 311 | 59 | 0.1231733 | 0.3289796 | 252 | 0.1200572 | 0.3251058 | 236 | 44 | 0.1225627 | 0.3283922 | 192 | 0.1219822 | 0.3273693 | 75 | 15 | 0.1250000 | 0.3321056 | 60 | 0.1142857 | 0.3184614 |
| 4109685210 | 210 | 4109685 | 0.0000000 | condition_era group during day -365 through -1 days relative to index: Laceration of foot | 2 | 1 | 0.0020877 | 0.0456912 | 1 | 0.0004764 | 0.0218270 | 1 | 1 | 0.0027855 | 0.0527780 | 0 | 0.0000000 | 0.0000000 | 1 | 0 | 0.0000000 | 0.0000000 | 1 | 0.0019048 | 0.0436436 |
| 4112343209 | 209 | 4112343 | 0.0000000 | condition_era group any time prior through -1 days relative to index: Acute viral pharyngitis | 2359 | 443 | 0.9248434 | 0.2639195 | 1916 | 0.9128156 | 0.2821723 | 1756 | 329 | 0.9164345 | 0.2771213 | 1427 | 0.9066074 | 0.2910743 | 603 | 114 | 0.9500000 | 0.2188588 | 489 | 0.9314286 | 0.2529650 |
| 4112343210 | 210 | 4112343 | 0.0000000 | condition_era group during day -365 through -1 days relative to index: Acute viral pharyngitis | 173 | 31 | 0.0647182 | 0.2462851 | 142 | 0.0676513 | 0.2512064 | 130 | 21 | 0.0584958 | 0.2350062 | 109 | 0.0692503 | 0.2539600 | 43 | 10 | 0.0833333 | 0.2775443 | 33 | 0.0628571 | 0.2429373 |
| 4113008209 | 209 | 4113008 | 0.1200263 | condition_era group any time prior through -1 days relative to index: Laceration of hand | 287 | 63 | 0.1315240 | 0.3383259 | 224 | 0.1067175 | 0.3088273 | 224 | 53 | 0.1476323 | 0.3552302 | 171 | 0.1086404 | 0.3112864 | 63 | 10 | 0.0833333 | 0.2775443 | 53 | 0.1009524 | 0.3015530 |
| 4113008210 | 210 | 4113008 | 0.0000000 | condition_era group during day -365 through -1 days relative to index: Laceration of hand | 6 | 2 | 0.0041754 | 0.0645494 | 4 | 0.0019057 | 0.0436228 | 3 | 1 | 0.0027855 | 0.0527780 | 2 | 0.0012706 | 0.0356348 | 3 | 1 | 0.0083333 | 0.0912871 | 2 | 0.0038095 | 0.0616624 |
| 4116491209 | 209 | 4116491 | 0.0000000 | condition_era group any time prior through -1 days relative to index: Escherichia coli urinary tract infection | 231 | 45 | 0.0939457 | 0.2920582 | 186 | 0.0886136 | 0.2842530 | 170 | 34 | 0.0947075 | 0.2932192 | 136 | 0.0864041 | 0.2810491 | 61 | 11 | 0.0916667 | 0.2897647 | 50 | 0.0952381 | 0.2938235 |
| 4116491210 | 210 | 4116491 | 0.0000000 | condition_era group during day -365 through -1 days relative to index: Escherichia coli urinary tract infection | 11 | 3 | 0.0062630 | 0.0789737 | 8 | 0.0038113 | 0.0616330 | 10 | 3 | 0.0083565 | 0.0911584 | 7 | 0.0044473 | 0.0665605 | 1 | 0 | 0.0000000 | 0.0000000 | 1 | 0.0019048 | 0.0436436 |
| 4132546209 | 209 | 4132546 | 0.0000000 | condition_era group any time prior through -1 days relative to index: Traumatic brain injury | 776 | 145 | 0.3027140 | 0.4599128 | 631 | 0.3006193 | 0.4586366 | 600 | 115 | 0.3203343 | 0.4672562 | 485 | 0.3081321 | 0.4618682 | 176 | 30 | 0.2500000 | 0.4348283 | 146 | 0.2780952 | 0.4484879 |
| 4132546210 | 210 | 4132546 | 0.0000000 | condition_era group during day -365 through -1 days relative to index: Traumatic brain injury | 27 | 4 | 0.0083507 | 0.0910951 | 23 | 0.0109576 | 0.1041283 | 19 | 2 | 0.0055710 | 0.0745350 | 17 | 0.0108005 | 0.1033956 | 8 | 2 | 0.0166667 | 0.1285559 | 6 | 0.0114286 | 0.1063932 |
| 4134304209 | 209 | 4134304 | 0.0000000 | condition_era group any time prior through -1 days relative to index: Fracture subluxation of wrist | 315 | 59 | 0.1231733 | 0.3289796 | 256 | 0.1219628 | 0.3273209 | 241 | 48 | 0.1337047 | 0.3408098 | 193 | 0.1226175 | 0.3281019 | 74 | 11 | 0.0916667 | 0.2897647 | 63 | 0.1200000 | 0.3252715 |
| 4134304210 | 210 | 4134304 | 0.0000000 | condition_era group during day -365 through -1 days relative to index: Fracture subluxation of wrist | 6 | 1 | 0.0020877 | 0.0456912 | 5 | 0.0023821 | 0.0487601 | 5 | 1 | 0.0027855 | 0.0527780 | 4 | 0.0025413 | 0.0503632 | 1 | 0 | 0.0000000 | 0.0000000 | 1 | 0.0019048 | 0.0436436 |
| 4142905209 | 209 | 4142905 | 0.0000000 | condition_era group any time prior through -1 days relative to index: Fracture of rib | 168 | 40 | 0.0835073 | 0.2769367 | 128 | 0.0609814 | 0.2393533 | 136 | 33 | 0.0919220 | 0.2893191 | 103 | 0.0654384 | 0.2473764 | 32 | 7 | 0.0583333 | 0.2353554 | 25 | 0.0476190 | 0.2131620 |
| 4142905210 | NA | NA | 0.0000000 | condition_era group during day -365 through -1 days relative to index: Fracture of rib | 1 | 0 | 0.0000000 | 0.0000000 | 1 | 0.0004764 | 0.0218270 | 1 | 0 | 0.0000000 | 0.0000000 | 1 | 0.0006353 | 0.0252056 | NA | NA | NA | NA | NA | NA | NA |
| 4149245209 | 209 | 4149245 | 0.0000000 | condition_era group any time prior through -1 days relative to index: Rupture of patellar tendon | 41 | 7 | 0.0146138 | 0.1201264 | 34 | 0.0161982 | 0.1262672 | 31 | 6 | 0.0167131 | 0.1283732 | 25 | 0.0158831 | 0.1250630 | 10 | 1 | 0.0083333 | 0.0912871 | 9 | 0.0171429 | 0.1299274 |
| 4149245210 | 210 | 4149245 | 0.0000000 | condition_era group during day -365 through -1 days relative to index: Rupture of patellar tendon | 2 | 0 | 0.0000000 | 0.0000000 | 2 | 0.0009528 | 0.0308607 | 2 | 0 | 0.0000000 | 0.0000000 | 2 | 0.0012706 | 0.0356348 | NA | NA | NA | NA | NA | NA | NA |
| 4152936209 | 209 | 4152936 | -0.0292760 | condition_era group any time prior through -1 days relative to index: Laceration of thigh | 296 | 43 | 0.0897704 | 0.2861513 | 253 | 0.1205336 | 0.3256620 | 221 | 33 | 0.0919220 | 0.2893191 | 188 | 0.1194409 | 0.3244097 | 75 | 10 | 0.0833333 | 0.2775443 | 65 | 0.1238095 | 0.3296783 |
| 4152936210 | 210 | 4152936 | 0.0000000 | condition_era group during day -365 through -1 days relative to index: Laceration of thigh | 6 | 1 | 0.0020877 | 0.0456912 | 5 | 0.0023821 | 0.0487601 | 4 | 0 | 0.0000000 | 0.0000000 | 4 | 0.0025413 | 0.0503632 | 2 | 1 | 0.0083333 | 0.0912871 | 1 | 0.0019048 | 0.0436436 |
| 4155034209 | 209 | 4155034 | 0.0000000 | condition_era group any time prior through -1 days relative to index: Laceration of forearm | 297 | 50 | 0.1043841 | 0.3060779 | 247 | 0.1176751 | 0.3222998 | 225 | 38 | 0.1058496 | 0.3080744 | 187 | 0.1188056 | 0.3236624 | 72 | 12 | 0.1000000 | 0.3012579 | 60 | 0.1142857 | 0.3184614 |
| 4155034210 | 210 | 4155034 | 0.0000000 | condition_era group during day -365 through -1 days relative to index: Laceration of forearm | 7 | 3 | 0.0062630 | 0.0789737 | 4 | 0.0019057 | 0.0436228 | 4 | 1 | 0.0027855 | 0.0527780 | 3 | 0.0019060 | 0.0436297 | 3 | 2 | 0.0166667 | 0.1285559 | 1 | 0.0019048 | 0.0436436 |
| 4156265209 | 209 | 4156265 | -0.0733670 | condition_era group any time prior through -1 days relative to index: Facial laceration | 303 | 43 | 0.0897704 | 0.2861513 | 260 | 0.1238685 | 0.3295100 | 216 | 29 | 0.0807799 | 0.2728772 | 187 | 0.1188056 | 0.3236624 | 87 | 14 | 0.1166667 | 0.3223687 | 73 | 0.1390476 | 0.3463262 |
| 4156265210 | 210 | 4156265 | 0.0000000 | condition_era group during day -365 through -1 days relative to index: Facial laceration | 7 | 1 | 0.0020877 | 0.0456912 | 6 | 0.0028585 | 0.0534012 | 6 | 1 | 0.0027855 | 0.0527780 | 5 | 0.0031766 | 0.0562898 | 1 | 0 | 0.0000000 | 0.0000000 | 1 | 0.0019048 | 0.0436436 |
| 4166224209 | 209 | 4166224 | 0.0000000 | condition_era group any time prior through -1 days relative to index: Rupture of appendix | 29 | 4 | 0.0083507 | 0.0910951 | 25 | 0.0119104 | 0.1085089 | 20 | 2 | 0.0055710 | 0.0745350 | 18 | 0.0114358 | 0.1063590 | 9 | 2 | 0.0166667 | 0.1285559 | 7 | 0.0133333 | 0.1148071 |
| 4218389209 | 209 | 4218389 | 0.0000000 | condition_era group any time prior through -1 days relative to index: Whiplash injury to neck | 459 | 91 | 0.1899791 | 0.3926945 | 368 | 0.1753216 | 0.3803325 | 351 | 70 | 0.1949861 | 0.3967429 | 281 | 0.1785260 | 0.3830767 | 108 | 21 | 0.1750000 | 0.3815603 | 87 | 0.1657143 | 0.3721786 |
| 4218389210 | 210 | 4218389 | 0.0000000 | condition_era group during day -365 through -1 days relative to index: Whiplash injury to neck | 14 | 2 | 0.0041754 | 0.0645494 | 12 | 0.0057170 | 0.0754124 | 11 | 1 | 0.0027855 | 0.0527780 | 10 | 0.0063532 | 0.0794789 | 3 | 1 | 0.0083333 | 0.0912871 | 2 | 0.0038095 | 0.0616624 |
| 4230399209 | 209 | 4230399 | 0.0000000 | condition_era group any time prior through -1 days relative to index: Closed fracture of hip | 61 | 12 | 0.0250522 | 0.1564470 | 49 | 0.0233444 | 0.1510310 | 43 | 9 | 0.0250696 | 0.1565549 | 34 | 0.0216010 | 0.1454230 | 18 | 3 | 0.0250000 | 0.1567796 | 15 | 0.0285714 | 0.1667575 |
| 4237458209 | 209 | 4237458 | 0.0000000 | condition_era group any time prior through -1 days relative to index: Fracture of clavicle | 310 | 52 | 0.1085595 | 0.3114110 | 258 | 0.1229157 | 0.3284186 | 235 | 40 | 0.1114206 | 0.3150914 | 195 | 0.1238882 | 0.3295586 | 75 | 12 | 0.1000000 | 0.3012579 | 63 | 0.1200000 | 0.3252715 |
| 4237458210 | 210 | 4237458 | 0.0000000 | condition_era group during day -365 through -1 days relative to index: Fracture of clavicle | 8 | 0 | 0.0000000 | 0.0000000 | 8 | 0.0038113 | 0.0616330 | 7 | 0 | 0.0000000 | 0.0000000 | 7 | 0.0044473 | 0.0665605 | 1 | 0 | 0.0000000 | 0.0000000 | 1 | 0.0019048 | 0.0436436 |
| 4278672209 | 209 | 4278672 | 0.0000000 | condition_era group any time prior through -1 days relative to index: Fracture of forearm | 356 | 59 | 0.1231733 | 0.3289796 | 297 | 0.1414960 | 0.3486155 | 268 | 48 | 0.1337047 | 0.3408098 | 220 | 0.1397713 | 0.3468598 | 88 | 11 | 0.0916667 | 0.2897647 | 77 | 0.1466667 | 0.3541107 |
| 4278672210 | 210 | 4278672 | 0.0000000 | condition_era group during day -365 through -1 days relative to index: Fracture of forearm | 6 | 0 | 0.0000000 | 0.0000000 | 6 | 0.0028585 | 0.0534012 | 3 | 0 | 0.0000000 | 0.0000000 | 3 | 0.0019060 | 0.0436297 | 3 | 0 | 0.0000000 | 0.0000000 | 3 | 0.0057143 | 0.0754485 |
| 4280726209 | 209 | 4280726 | 0.0000000 | condition_era group any time prior through -1 days relative to index: Seasonal allergic rhinitis | 23 | 2 | 0.0041754 | 0.0645494 | 21 | 0.0100048 | 0.0995459 | 17 | 2 | 0.0055710 | 0.0745350 | 15 | 0.0095299 | 0.0971856 | 6 | 0 | 0.0000000 | 0.0000000 | 6 | 0.0114286 | 0.1063932 |
| 4280726210 | 210 | 4280726 | 0.0000000 | condition_era group during day -365 through -1 days relative to index: Seasonal allergic rhinitis | 3 | 0 | 0.0000000 | 0.0000000 | 3 | 0.0014293 | 0.0377874 | 1 | 0 | 0.0000000 | 0.0000000 | 1 | 0.0006353 | 0.0252056 | 2 | 0 | 0.0000000 | 0.0000000 | 2 | 0.0038095 | 0.0616624 |
| 4283893209 | 209 | 4283893 | 0.0000000 | condition_era group any time prior through -1 days relative to index: Sinusitis | 2554 | 475 | 0.9916493 | 0.0910951 | 2079 | 0.9904717 | 0.0971702 | 1914 | 356 | 0.9916435 | 0.0911584 | 1558 | 0.9898348 | 0.1003407 | 640 | 119 | 0.9916667 | 0.0912871 | 521 | 0.9923810 | 0.0870369 |
| 4283893210 | 210 | 4283893 | 0.0000000 | condition_era group during day -365 through -1 days relative to index: Sinusitis | 319 | 65 | 0.1356994 | 0.3428271 | 254 | 0.1210100 | 0.3262166 | 239 | 49 | 0.1364903 | 0.3437876 | 190 | 0.1207116 | 0.3258953 | 80 | 16 | 0.1333333 | 0.3413599 | 64 | 0.1219048 | 0.3274878 |
| 4285898209 | 209 | 4285898 | -0.0025791 | condition_era group any time prior through -1 days relative to index: Polyp of colon | 371 | 113 | 0.2359081 | 0.4250089 | 258 | 0.1229157 | 0.3284186 | 281 | 86 | 0.2395543 | 0.4274072 | 195 | 0.1238882 | 0.3295586 | 90 | 27 | 0.2250000 | 0.4193332 | 63 | 0.1200000 | 0.3252715 |
| 4285898210 | 210 | 4285898 | -0.0000447 | condition_era group during day -365 through -1 days relative to index: Polyp of colon | 371 | 113 | 0.2359081 | 0.4250089 | 258 | 0.1229157 | 0.3284186 | 281 | 86 | 0.2395543 | 0.4274072 | 195 | 0.1238882 | 0.3295586 | 90 | 27 | 0.2250000 | 0.4193332 | 63 | 0.1200000 | 0.3252715 |
| 4294548209 | 209 | 4294548 | -0.0823952 | condition_era group any time prior through -1 days relative to index: Acute bacterial sinusitis | 512 | 89 | 0.1858038 | 0.3893549 | 423 | 0.2015245 | 0.4012345 | 392 | 63 | 0.1754875 | 0.3809144 | 329 | 0.2090216 | 0.4067391 | 120 | 26 | 0.2166667 | 0.4137009 | 94 | 0.1790476 | 0.3837578 |
| 4294548210 | 210 | 4294548 | 0.0000000 | condition_era group during day -365 through -1 days relative to index: Acute bacterial sinusitis | 19 | 3 | 0.0062630 | 0.0789737 | 16 | 0.0076227 | 0.0869953 | 15 | 2 | 0.0055710 | 0.0745350 | 13 | 0.0082592 | 0.0905329 | 4 | 1 | 0.0083333 | 0.0912871 | 3 | 0.0057143 | 0.0754485 |
| 4296204209 | 209 | 4296204 | 0.0000000 | condition_era group any time prior through -1 days relative to index: First degree burn | 224 | 45 | 0.0939457 | 0.2920582 | 179 | 0.0852787 | 0.2793625 | 159 | 31 | 0.0863510 | 0.2812736 | 128 | 0.0813215 | 0.2734150 | 65 | 14 | 0.1166667 | 0.3223687 | 51 | 0.0971429 | 0.2964346 |
| 4296204210 | 210 | 4296204 | 0.0000000 | condition_era group during day -365 through -1 days relative to index: First degree burn | 4 | 0 | 0.0000000 | 0.0000000 | 4 | 0.0019057 | 0.0436228 | 2 | 0 | 0.0000000 | 0.0000000 | 2 | 0.0012706 | 0.0356348 | 2 | 0 | 0.0000000 | 0.0000000 | 2 | 0.0038095 | 0.0616624 |
| 4296205209 | 209 | 4296205 | 0.0000000 | condition_era group any time prior through -1 days relative to index: Second degree burn | 135 | 27 | 0.0563674 | 0.2308710 | 108 | 0.0514531 | 0.2209727 | 100 | 20 | 0.0557103 | 0.2296815 | 80 | 0.0508259 | 0.2197119 | 35 | 7 | 0.0583333 | 0.2353554 | 28 | 0.0533333 | 0.2249116 |
| 4296205210 | 210 | 4296205 | 0.0000000 | condition_era group during day -365 through -1 days relative to index: Second degree burn | 8 | 0 | 0.0000000 | 0.0000000 | 8 | 0.0038113 | 0.0616330 | 7 | 0 | 0.0000000 | 0.0000000 | 7 | 0.0044473 | 0.0665605 | 1 | 0 | 0.0000000 | 0.0000000 | 1 | 0.0019048 | 0.0436436 |
| 4299128209 | 209 | 4299128 | 0.0000000 | condition_era group any time prior through -1 days relative to index: Third degree burn | 14 | 2 | 0.0041754 | 0.0645494 | 12 | 0.0057170 | 0.0754124 | 12 | 2 | 0.0055710 | 0.0745350 | 10 | 0.0063532 | 0.0794789 | 2 | 0 | 0.0000000 | 0.0000000 | 2 | 0.0038095 | 0.0616624 |
| 4310024209 | 209 | 4310024 | 0.0000000 | condition_era group any time prior through -1 days relative to index: Angiodysplasia of stomach | 377 | 128 | 0.2672234 | 0.4429726 | 249 | 0.1186279 | 0.3234272 | 282 | 95 | 0.2646240 | 0.4417484 | 187 | 0.1188056 | 0.3236624 | 95 | 33 | 0.2750000 | 0.4483865 | 62 | 0.1180952 | 0.3230287 |
| 4310024210 | 210 | 4310024 | 0.0000000 | condition_era group during day -365 through -1 days relative to index: Angiodysplasia of stomach | 8 | 1 | 0.0020877 | 0.0456912 | 7 | 0.0033349 | 0.0576661 | 6 | 0 | 0.0000000 | 0.0000000 | 6 | 0.0038119 | 0.0616427 | 2 | 1 | 0.0083333 | 0.0912871 | 1 | 0.0019048 | 0.0436436 |
| 4329847209 | 209 | 4329847 | 0.0000000 | condition_era group any time prior through -1 days relative to index: Myocardial infarction | 5 | 2 | 0.0041754 | 0.0645494 | 3 | 0.0014293 | 0.0377874 | 5 | 2 | 0.0055710 | 0.0745350 | 3 | 0.0019060 | 0.0436297 | NA | NA | NA | NA | NA | NA | NA |
| 19002770409 | 409 | 19002770 | 0.0000000 | drug_era group any time prior through -1 days relative to index: desflurane | 5 | 1 | 0.0020877 | 0.0456912 | 4 | 0.0019057 | 0.0436228 | 4 | 1 | 0.0027855 | 0.0527780 | 3 | 0.0019060 | 0.0436297 | 1 | 0 | 0.0000000 | 0.0000000 | 1 | 0.0019048 | 0.0436436 |
| 19003953409 | 409 | 19003953 | 0.0000000 | drug_era group any time prior through -1 days relative to index: Rocuronium | 24 | 5 | 0.0104384 | 0.1017402 | 19 | 0.0090519 | 0.0947326 | 20 | 5 | 0.0139276 | 0.1173540 | 15 | 0.0095299 | 0.0971856 | 4 | 0 | 0.0000000 | 0.0000000 | 4 | 0.0076190 | 0.0870369 |
| 19003953410 | NA | NA | 0.0000000 | drug_era group during day -365 through -1 days relative to index: Rocuronium | 1 | 0 | 0.0000000 | 0.0000000 | 1 | 0.0004764 | 0.0218270 | 1 | 0 | 0.0000000 | 0.0000000 | 1 | 0.0006353 | 0.0252056 | NA | NA | NA | NA | NA | NA | NA |
| 19010482409 | 409 | 19010482 | 0.0000000 | drug_era group any time prior through -1 days relative to index: Cyclosporine | 5 | 0 | 0.0000000 | 0.0000000 | 5 | 0.0023821 | 0.0487601 | 4 | 0 | 0.0000000 | 0.0000000 | 4 | 0.0025413 | 0.0503632 | 1 | 0 | 0.0000000 | 0.0000000 | 1 | 0.0019048 | 0.0436436 |
| 19010482410 | 410 | 19010482 | 0.0000000 | drug_era group during day -365 through -1 days relative to index: Cyclosporine | 2 | 0 | 0.0000000 | 0.0000000 | 2 | 0.0009528 | 0.0308607 | 2 | 0 | 0.0000000 | 0.0000000 | 2 | 0.0012706 | 0.0356348 | NA | NA | NA | NA | NA | NA | NA |
| 19016749409 | 409 | 19016749 | 0.0000000 | drug_era group any time prior through -1 days relative to index: remifentanil | 12 | 2 | 0.0041754 | 0.0645494 | 10 | 0.0047642 | 0.0688748 | 11 | 2 | 0.0055710 | 0.0745350 | 9 | 0.0057179 | 0.0754244 | 1 | 0 | 0.0000000 | 0.0000000 | 1 | 0.0019048 | 0.0436436 |
| 19039298409 | 409 | 19039298 | 0.0000000 | drug_era group any time prior through -1 days relative to index: sevoflurane | 2 | 0 | 0.0000000 | 0.0000000 | 2 | 0.0009528 | 0.0308607 | 2 | 0 | 0.0000000 | 0.0000000 | 2 | 0.0012706 | 0.0356348 | NA | NA | NA | NA | NA | NA | NA |
| 19059528409 | 409 | 19059528 | 0.0000000 | drug_era group any time prior through -1 days relative to index: Alfentanil | 4 | 1 | 0.0020877 | 0.0456912 | 3 | 0.0014293 | 0.0377874 | 3 | 1 | 0.0027855 | 0.0527780 | 2 | 0.0012706 | 0.0356348 | 1 | 0 | 0.0000000 | 0.0000000 | 1 | 0.0019048 | 0.0436436 |
| 19078219409 | 409 | 19078219 | 0.0000000 | drug_era group any time prior through -1 days relative to index: Sufentanil | 4 | 1 | 0.0020877 | 0.0456912 | 3 | 0.0014293 | 0.0377874 | 3 | 1 | 0.0027855 | 0.0527780 | 2 | 0.0012706 | 0.0356348 | 1 | 0 | 0.0000000 | 0.0000000 | 1 | 0.0019048 | 0.0436436 |
| 19127890409 | 409 | 19127890 | 0.0000000 | drug_era group any time prior through -1 days relative to index: Inert Ingredients | 636 | 112 | 0.2338205 | 0.4237018 | 524 | 0.2496427 | 0.4329093 | 472 | 81 | 0.2256267 | 0.4185778 | 391 | 0.2484117 | 0.4322291 | 164 | 31 | 0.2583333 | 0.4395535 | 133 | 0.2533333 | 0.4353350 |
| 40481087209 | 209 | 40481087 | 0.0000000 | condition_era group any time prior through -1 days relative to index: Viral sinusitis | 2544 | 472 | 0.9853862 | 0.1201264 | 2072 | 0.9871367 | 0.1127114 | 1905 | 353 | 0.9832869 | 0.1283732 | 1552 | 0.9860229 | 0.1174331 | 639 | 119 | 0.9916667 | 0.0912871 | 520 | 0.9904762 | 0.0972168 |
| 40481087210 | 210 | 40481087 | 0.0000000 | condition_era group during day -365 through -1 days relative to index: Viral sinusitis | 276 | 58 | 0.1210856 | 0.3265678 | 218 | 0.1038590 | 0.3051502 | 204 | 43 | 0.1197772 | 0.3251539 | 161 | 0.1022872 | 0.3031219 | 72 | 15 | 0.1250000 | 0.3321056 | 57 | 0.1085714 | 0.3113975 |
| 40486433209 | 209 | 40486433 | 0.0000000 | condition_era group any time prior through -1 days relative to index: Perennial allergic rhinitis | 135 | 23 | 0.0480167 | 0.2140251 | 112 | 0.0533587 | 0.2248014 | 103 | 17 | 0.0473538 | 0.2126908 | 86 | 0.0546379 | 0.2273442 | 32 | 6 | 0.0500000 | 0.2188588 | 26 | 0.0495238 | 0.2171659 |
| 40486433210 | 210 | 40486433 | 0.0000000 | condition_era group during day -365 through -1 days relative to index: Perennial allergic rhinitis | 4 | 1 | 0.0020877 | 0.0456912 | 3 | 0.0014293 | 0.0377874 | 4 | 1 | 0.0027855 | 0.0527780 | 3 | 0.0019060 | 0.0436297 | NA | NA | NA | NA | NA | NA | NA |
| 44782520209 | 209 | 44782520 | 0.0000000 | condition_era group any time prior through -1 days relative to index: Chronic paralysis due to lesion of spinal cord | 3 | 0 | 0.0000000 | 0.0000000 | 3 | 0.0014293 | 0.0377874 | 2 | 0 | 0.0000000 | 0.0000000 | 2 | 0.0012706 | 0.0356348 | 1 | 0 | 0.0000000 | 0.0000000 | 1 | 0.0019048 | 0.0436436 |