https://rpubs.com/alex_istrate/526483

# 1 Methods

Am folosit Microsot Excel 2016 pentru managementul bazei de date. Pentru toate analizele statistice È™i graficele ulterioare am folosit R 3.6.0. Am considerat p < 0.05 ca fiind semnificativ statistic È™i p < 0.1 ca prezentÃ¢nd doar o tendinÈ›Äƒ spre semnificativitate statisticÄƒ.

 Factor Detalis Pre Post Statistics Examination 30 (50.0%) 30 (50.0%) Weight (g) M (min:max) 236 (210:258) 249.5 (193:296) Paired T-test: p=0.010 Î¼ Â±DS 233.38 Â±14.3 246.87 Â±20.2 EDV M (min:max) 5.8 (3.24:7.1) 5.65 (4.52:7.52) Paired T-test: p=0.579 Î¼ Â±DS 5.73 Â±0.746 5.83 Â±0.837 ESV M (min:max) 3.67 (1.11:61.67) 3.7 (2.58:5.95) Wilcoxon paired test: p=0.732 Î¼ Â±DS 7.32 Â±14.0 3.89 Â±0.935 EF(M) M (min:max) 70.83 (45:95.67) 69.67 (43:83) Paired T-test: p=0.547 Î¼ Â±DS 70.04 Â±11.2 68.05 Â±10.3 SF(M) M (min:max) 37.08 (19.38:65.76) 34.66 (18.45:46.79) Wilcoxon paired test: p=0.578 Î¼ Â±DS 36.20 Â±9.44 33.85 Â±7.28 EDV(S) M (min:max) 0.15 (0.07:0.32) 0.18 (0.08:0.28) Paired T-test: p=0.236 Î¼ Â±DS 0.163 Â±0.0678 0.183 Â±0.0462 ESV(S) M (min:max) 0.04 (0.01:0.6) 0.05 (0.03:0.09) Wilcoxon paired test: p=0.135 Î¼ Â±DS 0.0629 Â±0.107 0.0525 Â±0.0167 EF(A2C) M (min:max) 77.53 (47.84:87.62) 72.05 (61.63:84.27) Paired T-test: p=0.183 Î¼ Â±DS 74.15 Â±9.81 71.73 Â±5.19 Î¼ Â±DS = Mean (standard deviation); M (min:max) = Median (min:max);

# 2 Results

## 2.1 NT-proBNP

Table 1: Summary statistics: NT-proBNP (pg/mL).

 NT-proBNP (pg/mL) N (%) Mean Â±SD Median (Min:Max) Grup: NT-proBNP (pg/mL) (Shapiro-Wilk normality test: p=0.130) (total) 39 (100.0%) 435.92 Â±129.9 432.3 (245.1:800.9) Grup: Group (ANOVA: p=0.162) before treatment 14 (35.9%) 407.25 Â±120.7 377.7 (245.1:659.1) control 8 (20.5%) 377.83 Â±114.0 355.1 (258.6:579.5) 50mg DFP 7 (17.9%) 469.05 Â±87.3 488.4 (372.5:586.9) 100mg DFP 10 (25.6%) 499.34 Â±159.5 435.8 (282.9:800.9)

Figure 1: Box & violon plots of NT-proBNP (pg/mL) by group. p-values from planned contrasts comparrisons. Diamonds denote means. Dotted line is the overall mean.