data pulled: 2019-08-26
written: 2019-08-26
last ran: 2019-08-26
website: http://rpubs.com/navona/RISH_matching_ZHP


General description

This code is used to identify matched controls, as required to test an implementation of the RISH harmonization method described in Karayumak et al., 2019. We use data from the SPINS study, and match 5 target sites (CMP, MRC, MRP, ZHH, ZHP) to the reference site (CMH).

In all cases, we aim to identify the gold-standard of n=20 matched ‘healthy control’ participants (or at least, the recommended n=16-18), on the basis of sex, age,IQ (here, established by WTAR), and handedness.


Data count

reference
targets
CMH CMP MRC MRP ZHH ZHP
female 16 6 9 10 5 17
male 23 3 13 11 7 17


Before matching


CMH ZHP p test
n 39 34
age (mean (SD)) 27.08 (8.34) 35.26 (11.18) 0.001
sex = male (%) 23 (59.0) 17 (50.0) 0.594
wtar_std (mean (SD)) 115.33 (9.39) 112.79 (12.10) 0.317
males
CMH ZHP p test
n 23 17
age (mean (SD)) 26.78 (8.23) 39.71 (11.08) <0.001
wtar_std (mean (SD)) 115.35 (9.20) 115.35 (11.59) 0.999
females
CMH ZHP p test
n 16 17
age (mean (SD)) 27.50 (8.75) 30.82 (9.65) 0.309
wtar_std (mean (SD)) 115.31 (9.95) 110.24 (12.39) 0.206


After matching


CMH ZHP p test
n 20 20
age (mean (SD)) 28.80 (10.12) 34.95 (10.40) 0.066
sex = male (%) 10 (50.0) 10 (50.0) 1.000
wtar_std (mean (SD)) 115.45 (10.28) 113.15 (13.84) 0.554
distance (mean (SD)) 0.41 (0.25) 0.55 (0.22) 0.084


List of matched pairs


males

SPN01_CMH_0073 SPN01_ZHP_0170
SPN01_CMH_0123 SPN01_ZHP_0138
SPN01_CMH_0135 SPN01_ZHP_0137
SPN01_CMH_0065 SPN01_ZHP_0119
SPN01_CMH_0113 SPN01_ZHP_0166
SPN01_CMH_0171 SPN01_ZHP_0115
SPN01_CMH_0040 SPN01_ZHP_0163
SPN01_CMH_0155 SPN01_ZHP_0107
SPN01_CMH_0149 SPN01_ZHP_0118
SPN01_CMH_0038 SPN01_ZHP_0136

females

SPN01_CMH_0026 SPN01_ZHP_0116
SPN01_CMH_0020 SPN01_ZHP_0122
SPN01_CMH_0125 SPN01_ZHP_0074
SPN01_CMH_0066 SPN01_ZHP_0139
SPN01_CMH_0109 SPN01_ZHP_0145
SPN01_CMH_0194 SPN01_ZHP_0142
SPN01_CMH_0017 SPN01_ZHP_0108
SPN01_CMH_0007 SPN01_ZHP_0168
SPN01_CMH_0014 SPN01_ZHP_0152
SPN01_CMH_0134 SPN01_ZHP_0073

Special notes

Because we could not match on the basis of handedness (established by EHI ≥ .5) for another site, we did not attempt to match on the basis of handedness here (nor will we for any other target site).