data pulled: 2019-08-26
written: 2019-08-26
last ran: 2019-08-26
website: http://rpubs.com/navona/RISH_matching_MRP

General description

This code is used to identify matched controls, as required to test an implementation of the RISH harmonization method described in Karayumak et al., 2019. We use data from the SPINS study, and match 5 target sites (CMP, MRC, MRP, ZHH, ZHP) to the reference site (CMH).

In all cases, we aim to identify the gold-standard of n=20 matched ‘healthy control’ participants (or at least, the recommended n=16-18), on the basis of sex, age,IQ (here, established by WTAR), and handedness.

Data count

	reference	targets
	CMH	CMP	MRC	MRP	ZHH	ZHP
female	16	6	9	10	5	17
male	23	3	13	11	7	17

Before matching

	CMH	MRP	p
n	39	21
age (mean (SD))	27.08 (8.34)	34.29 (11.79)	0.008
sex = male (%)	23 (59.0)	11 (52.4)	0.827
wtar_std (mean (SD))	115.33 (9.39)	109.19 (11.28)	0.028

males
	CMH	MRP	p
n	23	11
age (mean (SD))	26.78 (8.23)	31.73 (11.95)	0.167
wtar_std (mean (SD))	115.35 (9.20)	107.27 (13.20)	0.046

females
	CMH	MRP	p
n	16	10
age (mean (SD))	27.50 (8.75)	37.10 (11.54)	0.024
wtar_std (mean (SD))	115.31 (9.95)	111.30 (8.92)	0.309

After matching

	CMH	MRP	p
n	20	20
age (mean (SD))	29.85 (9.24)	34.75 (11.89)	0.154
sex = male (%)	10 (50.0)	10 (50.0)	1.000
wtar_std (mean (SD))	112.35 (9.49)	110.30 (10.33)	0.517
distance (mean (SD))	0.37 (0.18)	0.46 (0.22)	0.179

List of matched pairs

males

SPN01_CMH_0044	SPN01_MRP_0088
SPN01_CMH_0008	SPN01_MRP_0162
SPN01_CMH_0040	SPN01_MRP_0100
SPN01_CMH_0152	SPN01_MRP_0152
SPN01_CMH_0113	SPN01_MRP_0144
SPN01_CMH_0030	SPN01_MRP_0095
SPN01_CMH_0073	SPN01_MRP_0136
SPN01_CMH_0123	SPN01_MRP_0125
SPN01_CMH_0065	SPN01_MRP_0157
SPN01_CMH_0031	SPN01_MRP_0102

females

SPN01_CMH_0066	SPN01_MRP_0122
SPN01_CMH_0007	SPN01_MRP_0139
SPN01_CMH_0023	SPN01_MRP_0082
SPN01_CMH_0134	SPN01_MRP_0101
SPN01_CMH_0005	SPN01_MRP_0081
SPN01_CMH_0026	SPN01_MRP_0123
SPN01_CMH_0016	SPN01_MRP_0076
SPN01_CMH_0194	SPN01_MRP_0156
SPN01_CMH_0020	SPN01_MRP_0128
SPN01_CMH_0125	SPN01_MRP_0127

Special notes

Because we could not match on the basis of handedness (established by EHI ≥ .5) for another site, we did not attempt to match on the basis of handedness here (nor will we for any other target site).

SPINS participant matching CMH & MRP