M. Drew LaMar
February 15, 2019
Quote: “Models must be derived to carefully represent each of the science hypotheses.”
\[ H_{1} \Leftrightarrow g_{1}, \ H_{2} \Leftrightarrow g_{2}, \ldots, H_{k} \Leftrightarrow g_{k}. \]
Scientific Question: What is the support or empirical evidence for the ith hypothesis (via its corresponding model),
relative to others in the set .
Model Selection: What is the the
evidence for each of the hypotheses (and their associated models),given the data .
“All models are wrong, but some are useful.”
- Box
Example: Population survival \[ n_{t+1} = s\cdot n_{t} \]
Assumptions:
Discuss: What about Hardy-Weinberg equilibrium? What are the assumptions and approximations that go into this model?
Three common approaches have emerged for general parameter estimation:
Definition: The
maximum likelihood estimate (MLE) is the value of the parameter that is most likely, given the data and model.
Quote: “A person new to statistical thinking often finds it difficult to relate data, model, and model parameters that must be estimated. These are hard concepts to understand and the concepts are wound into the issue of parsimony. Let the data be fixed and then realize the information in the data is also fixed, then some of this information is "expended” each time a parameter is estimated. Thus, the data will only “support” a certain number of estimates, as this limit is exceeded parameter estimates become either very uncertain (e.g., large standard errors) or reach the point where they are not estimable.“