• Primary Consultant: Carly Hammond
• Secondary Consultant: Hana Sagor
• Faculty Advisor: Katie McLaughlin
• Department: Animal Sciences
• Degree Objective: PhD
• Statistical Background: ST 511

"The aim of this study was to determine LHR expression (percentage of LHR positive cells, LHR staining intensity) in a larger sample set of dogs with known lymphoma phenotypes. We hypothesized that LHR expression would differ with body weight, breed, sex, and lymphoma phenotype."

• Tissues obtained from 47 dogs with lymphoma from a national tissue archive (not random sample)
• One tissue slide per dog analyzed, all by the same individual, for intensity of LHR staining and percentage of LHR positive cells
• Intensity: Visual assessment (0-3)
• % positive: 0-100%, counted

Does body weight, breed, sex, tumor type, spayed/neutered vs intact, have an impact on LHR staining intensity and/or percentage of LHR positive cells?

• No randomization. Client wants to treat this as a pilot study for future work.
• Tumor type is not complete (12 of 47 missing)
• There were only 6 intact dogs, none of which were female.

• What analysis procedures should be used?
• What R packages should be used to implement these procedures?