1 Multilevel classes results (2by2)

Means, percentages, and 95% CIs of the characteristics by latent class memberships in the UK adults (NDNS RP 2008/09-2015/16, sample size = 6155).
Variables Latent class = 1 Latent class = 2 P value *
Total (%) 66.4 (64.8 , 68.1) 33.6 (31.9 , 35.2)
Countries (%)
England 83.1 (80.9 , 85.1) 85.4 (83.0 , 87.5) 0.203
Northern Ireland 3.0 (2.3 , 3.9) 2.3 (1.7 , 3.1)
Scotland 8.9 (7.2 , 11.0) 7.7 (5.9 , 9.9)
Wales 5.0 (4.1 , 6.0) 4.6 (3.6 , 6.0)
Age (years) 47.3 (46.4, 48.2) 50.1 (49.1, 51.1) < 0.001
Sex (%)
Men 47.3 (45.2 , 49.5) 51.0 (48.1 , 53.9) 0.048
Women 52.7 (50.5 , 54.8) 49.0 (46.1 , 51.9)
Survey years (%)
1 13.1 (10.8, 15.8) 15.0 (12.1, 18.5) 0.365
2 12.3 (10.1, 14.9) 11.9 (9.4, 14.2)
3 12.0 (9.8, 14.8) 10.4 (8.2, 13.1)
4 13.2 (10.9, 16.0) 11.4 (9.0, 14.2)
5 13.0 (10.8, 15.7) 13.9 (11.1, 17.3)
6 12.0 (9.9, 14.4) 11.1 (8.8, 13.9)
7 12.3 (10.1,14.9) 13.5 (10.9, 16.7)
8 12.0 (9.9, 14.5) 12.8 (10.3, 15.8)
BMI (kg/m^2) 27.2 (26.9, 27.5) 27.7 (27.5, 28.1) 0.007
WC (cm) 92.6 (91.9, 93.3) 94.2 (93.1, 95.2) 0.013
Smoking status (%)
Current 19.8 (18.2 , 21.4) 23.8 (21.3 , 26.5) < 0.001
Ex-smoker 22.5 (20.8 , 24.2) 28.0 (25.4 , 30.7)
Never 57.8 (55.7 , 59.8) 48.2 (45.3 , 51.1)
Current drinking status (%)
Yes 23.1 (21.3 , 25.1) 11.1 (9.5 , 13.0) < 0.001
Hypertension (%)
Yes 27.4 (25.0 , 29.9) 32.6 (29.3 , 36.1) 0.012
Total energy intake (KJ) 7425.7 (7323.7, 7527.8) 8149.9 (7997.3, 8302.7) < 0.001
Carbohydrate intake (g) 226.0 (222.8, 229.3) 210 (206.1, 213.9) < 0.001
Carbohydrate percent (%) 48.3 (48.0, 48.6) 40.9 (40.6, 41.3) < 0.001
Glucose (mmol/l) 5.13 (5.09, 5.17) 5.17 (5.11, 5.22) 0.292
A1C (%) 5.49 (5.47, 5.52) 5.47 (5.44,5.51) 0.264
DM § 4.1 (3.1 , 5.3 ) 5.9 (4.3 , 8.0 ) 0.061
Physical activity (hours/day) 1.51 (1.39, 1.63) 1.64 (1.45, 1.82) 0.244
* For continuous variables, the F test was used to determine differences between latent classes. For categorical variables, differences between latent classes were assessed using the adjusted Pearson Chi-2 test for survey data.
Hypertension was defined as either systolic blood pressure >= 140 mmHg or diastolic blood pressure >= 90 mmHg, or under treatment for hypertension.
Carbohydrate percent indicates the percentage of energy from carbohydrate in total energy intake
§ DM was defined by A1C > 6.5%.
Physical activity was calculated as mean time spent at moderate or vigorous physical activity during the survey.
Note:
Abbreviations: CI, confidence intervals; NDNS RP, national dietary and nutrition survey rolling programme; BMI body mass index; WC, waist circumference; A1C, haemoglobin A1c; DM, diabetes mellitus.
Variables from the blood tests (glucose and A1C) are weighted by blood sample weights, the others are weighted by individual weights.
Glucose and A1C levels are estimated in subgroups of people without diabetes.

2 Multilevel classes results (3by2)

Means, percentages, and 95% CIs of the characteristics by latent class memberships in the UK adults (NDNS RP 2008/09-2015/16, sample size = 6155).
Variables Latent class = 1 Latent class = 2 P value *
Total (%) 59.3 (57.6, 61.0) 40.7 (39.0, 42.4)
Countries (%)
England 83.0 (80.7, 85.0) 85.2 (82.8, 87.3) 0.171
Northern Ireland 3.1 (2.4, 4.1) 2.2 (1.7, 3.0)
Scotland 8.8 (7.1, 10.9) 8.1 (6.3, 10.3)
Wales 5.1 (4.2, 6.3) 4.5 (3.5, 5.7)
Age (years) 46.9 (46.0, 47.9) 50.2 (49.2, 51.1) < 0.001
Sex (%)
Men 47.2 (45.0, 49.4) 50.6 (48.0, 53.2) 0.044
Women 52.8 (50.6, 55.0) 49.4 (46.8, 52.0)
Survey years (%)
1 12.8 (10.5, 15.5) 15.2 (12.3, 18.5) 0.192
2 12.1 (9.9, 14.7) 12.2 (9.7, 15.3)
3 12.4 (10.0, 15.2) 10.2 (8.1, 12.7)
4 13.3 (10.9, 16.1) 11.6 (9.3, 14.3)
5 12.8 (10.5, 15.5) 14.1 (11.4, 17.3)
6 11.9 (9.8, 14.3) 11.4 (9.2, 14.1)
7 12.7 (10.4, 15.4) 12.8 (10.3 15.7)
8 12.0 (10.0, 14.5) 12.6 (10.2, 15.5)
BMI (kg/m^2) 27.2 (26.9, 27.5) 27.7 (27.4, 27.9) 0.034
WC (cm) 92.6 (91.9, 93.3) 93.9 (92.9, 94.8) 0.033
Smoking status (%)
Current 20.5 (18.8, 22.2) 22.1 (19.9, 22.5) < 0.001
Ex-smoker 22.4 (20.6, 24.3) 27.2 (24.9, 29.5)
Never 57.2 (55.0, 59.4) 50.8 (48.2, 53.4)
Current drinking status (%)
Yes 24.6 (22.6, 26.6) 11.1 (9.7, 12.7) < 0.001
Hypertension (%)
Yes 27.7 (25.2, 30.3) 31.3 (28.4, 34.4) 0.065
Total energy intake (KJ) 7371.5 (7273.2, 7469.8) 8102.9 (7958.6, 8247.2) < 0.001
Carbohydrate intake (g) 226.9 (223.6, 230.2) 211.6 (207.7, 215.4) < 0.001
Carbohydrate percent (%) 48.8 (48.5, 49.1) 41.4 (41.0, 41.8) < 0.001
Glucose (mmol/l) 5.14 (5.09, 5.18) 5.15 (5.11, 5.20) 0.706
A1C (%) 5.49 (5.47, 5.52) 5.48 (5.44, 5.50) 0.29
DM § 4.2 (3.1, 5.5) 5.5 (4.1, 7.3) 0.158
Physical activity (hours/day) 1.49 (1.36, 1.62) 1.64 (1.48, 1.81) 0.163
* For continuous variables, the F test was used to determine differences between latent classes. For categorical variables, differences between latent classes were assessed using the adjusted Pearson Chi-2 test for survey data.
Hypertension was defined as either systolic blood pressure >= 140 mmHg or diastolic blood pressure >= 90 mmHg, or under treatment for hypertension.
Carbohydrate percent indicates the percentage of energy from carbohydrate in total energy intake
§ DM was defined by A1C > 6.5%.
Physical activity was calculated as mean time spent at moderate or vigorous physical activity during the survey.
Note:
Abbreviations: CI, confidence intervals; NDNS RP, national dietary and nutrition survey rolling programme; BMI body mass index; WC, waist circumference; A1C, haemoglobin A1c; DM, diabetes mellitus.
Variables from the blood tests (glucose and A1C) are weighted by blood sample weights, the others are weighted by individual weights.
Glucose and A1C levels are estimated in subgroups of people without diabetes.

3 LCGA 2 classes results

Means, percentages, and 95% CIs of the characteristics by latent class memberships in the UK adults (NDNS RP 2008/09-2015/16, sample size = 6155).
Variables Latent class = 1 Latent class = 2 P value *
Total (%) 68.0 (66.4, 69.9) 32.0 (30.4, 33.6)
Countries (%)
England 82.0 (79.7, 84.1) 87.9 (85.6, 89.9) < 0.001
Northern Ireland 3.3 (2.6, 4.3) 1.6 (1.1, 2.2)
Scotland 9.6 (7.7, 11.8) 6.2 (4.7, 8.3)
Wales 5.1 (4.2, 6.2) 4.3 (3.3, 5.6)
Age (years) 47.2 (46.4, 48.1) 50.4 (49.4, 51.4) < 0.001
Sex (%)
Men 47.6 (45.5, 49.8) 50.6 (47.8, 53.3) 0.098
Women 52.4 (50.2, 54.5) 49.4 (46.7, 52.2)
Survey years (%)
1 12.7 (10.4, 15.4) 16.0 (13.0, 19.5) 0.188
2 11.8 (9.6, 14.4) 12.9 (10.3, 16.1)
3 11.5 (9.3, 14.1) 11.5 (9.0, 14.6)
4 12.6 (10.4, 15.3) 12.6 (10.0, 15.7)
5 13.8 (11.4, 16.6) 12.3 (9.7, 15.4)
6 12.3 (10.2, 14.8) 10.3 (8.1, 12.9)
7 12.9 (10.7, 15.4) 12.4 (9.9, 15.6)
8 12.4 (10.2, 15.0) 12.0 (9.6, 14.9)
BMI (kg/m^2) 27.6 (27.3, 27.8) 27.1 (26.7, 27.3) 0.006
WC (cm) 93.4 (92.6, 94.1) 92.7 (91.8, 93.7) 0.309
Smoking status (%)
Current 20.7 (19.2, 22.4) 21.9 (19.5, 24.5) 0.016
Ex-smoker 23.1 (21.5, 24.9) 26.8 (24.4, 29.4)
Never 56.1 (54.1, 58.1) 51.3 (48.3, 54.2)
Current drinking status (%)
Yes 20.3 (18.5, 22.1) 16.6 (14.5, 18.9) 0.013
Hypertension (%)
Yes 28.1 (25.7, 30.6) 31.5 (28.1, 35.0) 0.111
Total energy intake (KJ) 7240.4 (7143.9, 7336.9) 8580.6 (8431.3, 8729.9) < 0.001
Carbohydrate intake (g) 207.4 (204.6, 210.3) 248.9 (244.3, 253.4) < 0.001
Carbohydrate percent (%) 45.7 (45.3, 46.0) 46.2 (45.7, 46.6) 0.071
Glucose (mmol/l) 5.14 (5.09, 5.18) 5.16 (5.10, 5.20) 0.603
A1C (%) 5.48 (5.46, 5.51) 5.50 (5.46, 5.53) 0.614
DM § 5.2 (4.1, 6.6) 3.8 (2.6, 5.6) 0.178
Physical activity (hours/day) 1.42 (1.30, 1.53) 1.85 (1.64, 2.06) < 0.001
* For continuous variables, the F test was used to determine differences between latent classes. For categorical variables, differences between latent classes were assessed using the adjusted Pearson Chi-2 test for survey data.
Hypertension was defined as either systolic blood pressure >= 140 mmHg or diastolic blood pressure >= 90 mmHg, or under treatment for hypertension.
Carbohydrate percent indicates the percentage of energy from carbohydrate in total energy intake
§ DM was defined by A1C > 6.5%.
Physical activity was calculated as mean time spent at moderate or vigorous physical activity during the survey.
Note:
Abbreviations: CI, confidence intervals; NDNS RP, national dietary and nutrition survey rolling programme; BMI body mass index; WC, waist circumference; A1C, haemoglobin A1c; DM, diabetes mellitus.
Variables from the blood tests (glucose and A1C) are weighted by blood sample weights, the others are weighted by individual weights.
Glucose and A1C levels are estimated in subgroups of people without diabetes.

4 LCGA 3 classes results

Means, percentages, and 95% CIs of the characteristics by latent class memberships in the UK adults (NDNS RP 2008/09-2015/16, sample size = 6155).
Variables Latent class = 1 Latent class = 2 Latent class = 3 P value *
Total (%) 28.4 (26.8, 30.1) 7.0 (6.2, 7.9) 64.6 (62.9, 66.2)
Countries (%)
England 81.4 (78.5, 84.0) 87.5 (82.9, 91.0) 84.6 (82.5, 86.4) 0.004
Northern Ireland 3.9 (2.9, 5.1) 0.6 (0.3, 1.2) 2.5 (2.0, 3.2)
Scotland 9.5 (7.4, 12.3) 6.2 (3.5, 10.6) 8.3 (6.7, 10.3)
Wales 5.2 (4.1, 6.6) 5.7 (3.8, 8.5) 4.6 (3.8, 5.6)
Age (years) 43.8 (42.4, 45.1) 49.1 (47.2, 50.9) 50.1 (49.3, 50.9) < 0.001
Sex (%)
Men 50.6 (47.3, 53.9) 49.6 (43.7, 55.4) 47.6 (45.4, 49.7) 0.273
Women 49.4 (46.1, 52.7) 50.4 (44.6, 56.3) 52.4 (50.3, 54.6)
Survey years (%)
1 11.4 (8.8, 14.7) 17.1 (12.4, 23.3) 14.4 (11.9, 17.4) 0.002
2 10.1 (7.8, 13.1) 18.3 (13.3, 24.7) 12.4 (10.2, 15.0)
3 13.9 (10.8, 17.7) 9.1 (5.7, 14.1) 10.7 (8.6, 13.1)
4 10.9 (8.5, 13.9) 13.8 (9.7, 19.4) 13.2 (10.9, 16.0)
5 13.5 (10.6, 17.0) 12.8 (8.4, 19.1) 13.3 (11.0, 16.1)
6 12.8 (10.1, 16.1) 8.7 (5.7, 12.9) 11.5 (9.5, 13.9)
7 14.3 (11.5, 17.6) 9.5 (6.5, 13.8) 12.4 (10.2, 15.0)
8 13.2 (10.5, 16.4) 10.5 (7.4, 14.8) 12.1 (9.9, 14.6)
BMI (kg/m^2) 27.5 (27.1, 27.9) 27.0 (26.4, 27.6) 27.4 (27.2, 27.6) 0.433
WC (cm) 93.3 (92.1, 94.5) 92.9 (90.9, 95.0) 93.1 (92.3, 93.8) 0.928
Smoking status (%)
Current 24.1 (21.5, 27.0) 30.0 (24.8, 35.8) 18.8 (17.2, 20.6) < 0.001
Ex-smoker 20.0 (17.6, 22.6) 27.5 (22.4, 33.2) 25.9 (24.1, 27.7)
Never 55.9 (52.7, 59.0) 42.5 (36.6, 48.7) 55.3 (53.2, 57.4)
Current drinking status (%)
Yes 24.6 (21.7, 27.7) 18.3 (14.0, 23.6) 16.8 (15.3, 18.4) < 0.001
Hypertension (%)
Yes 25.9 (22.3, 29.9) 31.8 (25.3, 39.1) 30.4 (27.9 32.8) 0.111
Total energy intake (KJ) 6713.8 (6575.7, 6851.8) 9256.0 (8850.8, 9661.2) 7916.9 (7814.0, 8019.9) < 0.001
Carbohydrate intake (g) 192.9 (188.5, 197.3) 275.6 (263.4, 287.8) 226.9 (223.9, 229.9) < 0.001
Carbohydrate percent (%) 45.8 (45.3, 46.4) 47.4 (46.5, 48.3) 45.6 (45.3, 45.9) 0.001
Glucose (mmol/l) 5.16 (5.08, 5.23) 5.09 (5.00, 5.18) 5.14 (5.10, 5.19) 0.537
A1C (%) 5.47 (5.42, 5.51) 5.48 (5.42, 5.54) 5.49 (5.47. 5.52) 0.403
DM § 5.9 (4.2, 8.2) 1.1 (0.2, 5.2) 4.7 (3.6, 6.0) 0.053
Physical activity (hours/day) 1.31 (1.14, 1.49) 1.82 (1.44, 2.19) 1.62 (1.49, 1.76) 0.018
* For continuous variables, the F test was used to determine differences between latent classes with Bonferroni correction to account for multiple testing across >2 classes. For categorical variables, differences between latent classes were assessed using the adjusted Pearson Chi-2 test for survey data.
Hypertension was defined as either systolic blood pressure >= 140 mmHg or diastolic blood pressure >= 90 mmHg, or under treatment for hypertension.
Carbohydrate percent indicates the percentage of energy from carbohydrate in total energy intake
§ DM was defined by A1C > 6.5%.
Physical activity was calculated as mean time spent at moderate or vigorous physical activity during the survey.
Note:
Abbreviations: CI, confidence intervals; NDNS RP, national dietary and nutrition survey rolling programme; BMI body mass index; WC, waist circumference; A1C, haemoglobin A1c; DM, diabetes mellitus.
Variables from the blood tests (glucose and A1C) are weighted by blood sample weights, the others are weighted by individual weights.
Glucose and A1C levels are estimated in subgroups of people without diabetes.