Comparing Nested Random Effects Structures

Updated Exclusion Criteria:

• 5-responses required
• No requirement for number of exams

Updated Sample Sizes:

• Exploratory: N = 75 (previous: N = 44)
• Confirmatory: N = 81 (previous: N = 51)

New Gammas Fit to Full Exploratory Data Frame:

• PA: 0.85
• NA: 0.91

Affect ~ outcome + PE + ( 1 + outcome + PE | cohort / exam_num / id)

• 2nd exam within cohort 3 is removed
• 4th exams for cohorts 5 and 6 are removed

Dataset	Affect	predictor	Estimate	SE	df	t_stat	p_Val
Exploratory	Positive	outcome	0.2683329	0.3062027	0.7721575	0.8763245	0.5739787
Exploratory	Positive	PE	3.6120281	0.7869309	3.7013053	4.5900193	0.0121156
Exploratory	Negative	outcome	-0.6520026	0.3776380	1.5165497	-1.7265279	0.2643527
Exploratory	Negative	PE	-2.5508725	0.8544520	4.7264693	-2.9853899	0.0328365
Confirmatory	Positive	outcome	0.3709480	0.1720507	5.2171812	2.1560385	0.0813225
Confirmatory	Positive	PE	3.1715136	0.6254922	2.2663061	5.0704288	0.0282184
Confirmatory	Negative	outcome	-0.6316818	0.2279122	22.3706362	-2.7716018	0.0110244
Confirmatory	Negative	PE	-2.3437053	0.6119888	1.8590463	-3.8296537	0.0694108

Affect ~ outcome + PE + ( 1 + outcome + PE | cohort / id / exam_num)

• 2nd exam within cohort 3 is removed
• 4th exams for cohorts 5 and 6 are removed

With new structure, PE is trending in exploratory dataset, and significant in confirmatory

Dataset	Affect	predictor	Estimate	SE	df	t_stat	p_Val
Exploratory	Positive	outcome	0.2571840	0.2973863	0.8681295	0.8648145	0.5630301
Exploratory	Positive	PE	3.5544008	0.6333976	1.1342790	5.6116426	0.0916340
Exploratory	Negative	outcome	-0.6884614	0.3520062	1.0254519	-1.9558220	0.2960804
Exploratory	Negative	PE	-2.6397819	0.7314900	2.5560499	-3.6087738	0.0472890
Confirmatory	Positive	outcome	0.4322902	0.1491801	59.7317552	2.8977741	0.0052473
Confirmatory	Positive	PE	3.4119439	0.5522137	43.9067564	6.1786659	0.0000002
Confirmatory	Negative	outcome	-0.6411406	0.2280482	24.8462890	-2.8114258	0.0094847
Confirmatory	Negative	PE	-2.3927946	0.6130528	2.3465342	-3.9030807	0.0459199

Affect ~ outcome + PE + ( 1 + outcome + PE | cohort / id) (i.e., no control for exam)

• 2nd exam within cohort 3 is removed
• 4th exams for cohorts 5 and 6 are removed

With new structure, PE is trending in exploratory dataset, and significant in confirmatory

Dataset	Affect	predictor	Estimate	SE	df	t_stat	p_Val
Exploratory	Positive	outcome	0.3559716	0.2607265	1.2430801	1.365307	0.3681100
Exploratory	Positive	PE	4.6291992	1.1327617	0.8700013	4.086649	0.1808906
Exploratory	Negative	outcome	-0.6713500	0.4152040	0.9455647	-1.616916	0.3628114
Exploratory	Negative	PE	-3.4036853	1.0165023	1.2503509	-3.348428	0.1436016
Confirmatory	Positive	outcome	0.4748991	0.1667799	32.2275032	2.847460	0.0076100
Confirmatory	Positive	PE	4.1616008	0.6863282	21.9004468	6.063572	0.0000043
Confirmatory	Negative	outcome	-0.6609985	0.3116713	18.0193044	-2.120819	0.0480693
Confirmatory	Negative	PE	-3.2627133	1.2444769	0.9888679	-2.621755	0.2342361

Affect ~ outcome + PE + ( 1 + outcome + PE | cohort / id) (i.e., no control for exam)

With new structure, PE is trending in exploratory dataset, and significant in confirmatory

Dataset	Affect	predictor	Estimate	SE	df	t_stat	p_Val
Exploratory	Positive	outcome	0.3459594	0.2682903	1.1879684	1.289496	0.3934047
Exploratory	Positive	PE	4.8071986	1.2471445	0.8845628	3.854564	0.1864750
Exploratory	Negative	outcome	-0.5742322	0.4853631	0.9277345	-1.183098	0.4582044
Exploratory	Negative	PE	-3.4359540	1.0724036	1.1675024	-3.203975	0.1631683
Confirmatory	Positive	outcome	0.4433729	0.1764300	47.0908035	2.513025	0.0154508
Confirmatory	Positive	PE	4.1496153	0.7766343	34.4634508	5.343075	0.0000059
Confirmatory	Negative	outcome	-0.4953469	0.2691990	3.7233333	-1.840077	0.1448847
Confirmatory	Negative	PE	-2.4340578	1.5383256	0.9745021	-1.582277	0.3634433