Updated Exclusion Criteria:
- 5-responses required
- No requirement for number of exams
Updated Sample Sizes:
- Exploratory: N = 75 (previous: N = 44)
- Confirmatory: N = 81 (previous: N = 51)
New Gammas Fit to Full Exploratory Data Frame:
Random Effects Structure I
Affect ~ outcome + PE + ( 1 + outcome + PE | cohort / exam_num / id)

| Exploratory |
Positive |
outcome |
0.3381905 |
0.2001976 |
5.608594 |
1.6892832 |
0.1455747 |
| Exploratory |
Positive |
PE |
3.7807479 |
0.7886752 |
4.262214 |
4.7937956 |
0.0074084 |
| Exploratory |
Negative |
outcome |
-0.6068125 |
0.3951412 |
1.215238 |
-1.5356852 |
0.3345566 |
| Exploratory |
Negative |
PE |
-2.6740427 |
0.8646741 |
3.286446 |
-3.0925439 |
0.0474750 |
| Confirmatory |
Positive |
outcome |
0.2158519 |
0.3170549 |
1.235805 |
0.6808031 |
0.6009263 |
| Confirmatory |
Positive |
PE |
3.1369099 |
0.5432564 |
5.822864 |
5.7742710 |
0.0013076 |
| Confirmatory |
Negative |
outcome |
-0.4572960 |
0.3317150 |
1.157256 |
-1.3785809 |
0.3759657 |
| Confirmatory |
Negative |
PE |
-1.9518399 |
0.7137204 |
1.074915 |
-2.7347402 |
0.2089239 |
Random Effects Structure II
Affect ~ outcome + PE + ( 1 + outcome + PE | cohort / id / exam_num)

With new structure, PE is trending in exploratory dataset, and significant in confirmatory
| Exploratory |
Positive |
outcome |
0.3102355 |
0.2160938 |
2.3624013 |
1.435652 |
0.2692764 |
| Exploratory |
Positive |
PE |
3.5752270 |
0.6013576 |
1.3909792 |
5.945259 |
0.0590905 |
| Exploratory |
Negative |
outcome |
-0.6449324 |
0.3796406 |
1.0432242 |
-1.698798 |
0.3309908 |
| Exploratory |
Negative |
PE |
-2.6717013 |
0.7686514 |
1.6284042 |
-3.475830 |
0.0980165 |
| Confirmatory |
Positive |
outcome |
0.4384121 |
0.2576754 |
0.9817883 |
1.701412 |
0.3416694 |
| Confirmatory |
Positive |
PE |
3.4700851 |
0.5053408 |
72.9347299 |
6.866822 |
0.0000000 |
| Confirmatory |
Negative |
outcome |
-0.5384790 |
0.2885021 |
1.1152864 |
-1.866465 |
0.2928893 |
| Confirmatory |
Negative |
PE |
-2.1758658 |
0.6399473 |
1.4356868 |
-3.400070 |
0.1190673 |