Updated Exclusion Criteria:
- 5-responses required
- No requirement for number of exams
Updated Sample Sizes:
- Exploratory: N = 75 (previous: N = 44)
- Confirmatory: N = 81 (previous: N = 51)
New Gammas Fit to Full Exploratory Data Frame:
Random Effects Structure I
Affect ~ outcome + PE + ( 1 + outcome + PE | cohort / exam_num / id)

| Exploratory |
Positive |
outcome |
0.2939259 |
0.3063250 |
0.6827217 |
0.9595230 |
0.5654511 |
| Exploratory |
Positive |
PE |
3.8793119 |
0.8978651 |
1.4873555 |
4.3205954 |
0.0816432 |
| Exploratory |
Negative |
outcome |
-0.6148613 |
0.4108051 |
0.9684240 |
-1.4967225 |
0.3805886 |
| Exploratory |
Negative |
PE |
-2.7892094 |
0.9311117 |
1.8078796 |
-2.9955689 |
0.1079370 |
| Confirmatory |
Positive |
outcome |
0.2112718 |
0.3194255 |
1.2488045 |
0.6614118 |
0.6091468 |
| Confirmatory |
Positive |
PE |
3.1232271 |
0.5349815 |
5.2264938 |
5.8380096 |
0.0017962 |
| Confirmatory |
Negative |
outcome |
-0.4587680 |
0.3329608 |
1.1294713 |
-1.3778440 |
0.3799484 |
| Confirmatory |
Negative |
PE |
-1.9634029 |
0.7033203 |
1.0581823 |
-2.7916200 |
0.2077783 |
Random Effects Structure II
Affect ~ outcome + PE + ( 1 + outcome + PE | cohort / id / exam_num)

With new structure, PE is trending in exploratory dataset, and significant in confirmatory
| Exploratory |
Positive |
outcome |
0.2771896 |
0.3069613 |
0.8026184 |
0.9030116 |
0.5602445 |
| Exploratory |
Positive |
PE |
3.7160393 |
0.7761725 |
0.7760435 |
4.7876460 |
0.1826861 |
| Exploratory |
Negative |
outcome |
-0.6695420 |
0.3669981 |
1.1837480 |
-1.8243748 |
0.2885669 |
| Exploratory |
Negative |
PE |
-2.7806832 |
0.8487211 |
1.0146715 |
-3.2763215 |
0.1857015 |
| Confirmatory |
Positive |
outcome |
0.4429418 |
0.2648576 |
0.9732648 |
1.6723774 |
0.3480611 |
| Confirmatory |
Positive |
PE |
3.4788673 |
0.5003967 |
64.1829506 |
6.9522184 |
0.0000000 |
| Confirmatory |
Negative |
outcome |
-0.5392715 |
0.2896359 |
1.0839537 |
-1.8618945 |
0.2987380 |
| Confirmatory |
Negative |
PE |
-2.1903448 |
0.6272350 |
1.4375740 |
-3.4920642 |
0.1147359 |