library(lme4)
## Loading required package: Matrix
str(Penicillin)
## 'data.frame':    144 obs. of  3 variables:
##  $ diameter: num  27 23 26 23 23 21 27 23 26 23 ...
##  $ plate   : Factor w/ 24 levels "a","b","c","d",..: 1 1 1 1 1 1 2 2 2 2 ...
##  $ sample  : Factor w/ 6 levels "A","B","C","D",..: 1 2 3 4 5 6 1 2 3 4 ...
summary(Penicillin)
##     diameter         plate     sample
##  Min.   :18.00   a      :  6   A:24  
##  1st Qu.:22.00   b      :  6   B:24  
##  Median :23.00   c      :  6   C:24  
##  Mean   :22.97   d      :  6   D:24  
##  3rd Qu.:24.00   e      :  6   E:24  
##  Max.   :27.00   f      :  6   F:24  
##                  (Other):108
xtabs(~ sample + plate, Penicillin)
##       plate
## sample a b c d e f g h i j k l m n o p q r s t u v w x
##      A 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1
##      B 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1
##      C 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1
##      D 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1
##      E 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1
##      F 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1
(model3 <- lmer(diameter ~ 1 + (1|plate) + (1|sample), Penicillin))
## Linear mixed model fit by REML ['lmerMod']
## Formula: diameter ~ 1 + (1 | plate) + (1 | sample)
##    Data: Penicillin
## REML criterion at convergence: 330.8606
## Random effects:
##  Groups   Name        Std.Dev.
##  plate    (Intercept) 0.8467  
##  sample   (Intercept) 1.9316  
##  Residual             0.5499  
## Number of obs: 144, groups:  plate, 24; sample, 6
## Fixed Effects:
## (Intercept)  
##       22.97
pr03 <- profile(model3)
pr03
##          .zeta    .sig01     .sig02    .sigma (Intercept)        .par
## 1  -3.99417206 0.4838555  1.7651456 0.5678654    22.97222      .sig01
## 2  -3.50158054 0.5155906  1.7655672 0.5632325    22.97222      .sig01
## 3  -3.00593303 0.5501255  1.7660303 0.5595740    22.97222      .sig01
## 4  -2.50732514 0.5879316  1.7665514 0.5567042    22.97222      .sig01
## 5  -2.00578109 0.6295624  1.7670055 0.5544754    22.97222      .sig01
## 6  -1.50127323 0.6756760  1.7678301 0.5527710    22.97222      .sig01
## 7  -0.99382080 0.7270530  1.7686329 0.5514916    22.97222      .sig01
## 8  -0.48494129 0.7844551  1.7695784 0.5505596    22.97222      .sig01
## 9   0.00000000 0.8455722  1.7706463 0.5499322    22.97222      .sig01
## 10  0.06301493 0.8540279  1.7707981 0.5498665    22.97222      .sig01
## 11  0.49239137 0.9151450  1.7719311 0.5495005    22.97222      .sig01
## 12  0.90338547 0.9799755  1.7731886 0.5492655    22.97222      .sig01
## 13  1.31372651 1.0518209  1.7746620 0.5491207    22.97222      .sig01
## 14  1.72258001 1.1315669  1.7763709 0.5490462    22.97222      .sig01
## 15  2.12996848 1.2204044  1.7783627 0.5490252    22.97222      .sig01
## 16  2.53587422 1.3197259  1.7806966 0.5490437    22.97222      .sig01
## 17  2.94028323 1.4311740  1.7834198 0.5490897    22.97222      .sig01
## 18  3.34318380 1.5566924  1.7866022 0.5491539    22.97222      .sig01
## 19  3.74456727 1.6985865  1.7903169 0.5492288    22.97222      .sig01
## 20 -3.72328360 0.8420462  0.7932702 0.5510652    22.97222      .sig02
## 21 -3.18524713 0.8426790  0.8683985 0.5506896    22.97222      .sig02
## 22 -2.63903802 0.8432874  0.9584947 0.5504130    22.97222      .sig02
## 23 -2.08300496 0.8438662  1.0684845 0.5502164    22.97222      .sig02
## 24 -1.51545244 0.8444091  1.2055422 0.5500829    22.97222      .sig02
## 25 -0.93793622 0.8449034  1.3793272 0.5499983    22.97222      .sig02
## 26 -0.37640640 0.8453247  1.5935817 0.5499507    22.97222      .sig02
## 27  0.00000000 0.8455722  1.7706463 0.5499322    22.97222      .sig02
## 28  0.03421088 0.8455933  1.7883528 0.5499309    22.97222      .sig02
## 29  0.34806602 0.8457757  1.9654174 0.5499218    22.97222      .sig02
## 30  0.72945369 0.8459706  2.2223728 0.5499158    22.97222      .sig02
## 31  1.10128662 0.8461330  2.5292370 0.5499134    22.97222      .sig02
## 32  1.46980983 0.8462686  2.9051208 0.5499132    22.97222      .sig02
## 33  1.83438070 0.8463785  3.3696830 0.5499142    22.97222      .sig02
## 34  2.19497627 0.8464658  3.9500691 0.5499159    22.97222      .sig02
## 35  2.55155044 0.8465341  4.6831498 0.5499175    22.97222      .sig02
## 36  2.90409347 0.8465860  5.6195405 0.5499190    22.97222      .sig02
## 37  3.25262538 0.8466240  6.8293029 0.5499202    22.97222      .sig02
## 38  3.59719294 0.8466513  8.4102331 0.5499211    22.97222      .sig02
## 39  3.93786393 0.8466696 10.4999789 0.5499219    22.97222      .sig02
## 40 -3.82024577 0.8565824  1.7721660 0.4358855    22.97222      .sigma
## 41 -3.34296821 0.8555540  1.7720237 0.4478394    22.97222      .sigma
## 42 -2.86530975 0.8544441  1.7718692 0.4603758    22.97222      .sigma
## 43 -2.38726013 0.8532446  1.7717031 0.4735338    22.97222      .sigma
## 44 -1.90880877 0.8519462  1.7715238 0.4873559    22.97222      .sigma
## 45 -1.42994498 0.8505386  1.7713295 0.5018880    22.97222      .sigma
## 46 -0.95066377 0.8490102  1.7711190 0.5171800    22.97222      .sigma
## 47 -0.47118486 0.8473485  1.7708901 0.5332783    22.97222      .sigma
## 48  0.00000000 0.8455722  1.7706463 0.5499322    22.97222      .sigma
## 49  0.15040035 0.8449729  1.7705643 0.5554315    22.97222      .sigma
## 50  0.59114324 0.8431186  1.7703101 0.5720854    22.97222      .sigma
## 51  1.02480250 0.8411404  1.7700397 0.5892956    22.97222      .sigma
## 52  1.45830737 0.8389943  1.7697470 0.6073711    22.97222      .sigma
## 53  1.89149050 0.8366635  1.7694299 0.6263624    22.97222      .sigma
## 54  2.32435026 0.8341281  1.7690868 0.6463305    22.97222      .sigma
## 55  2.75688111 0.8313655  1.7687124 0.6673413    22.97222      .sigma
## 56  3.18907760 0.8283504  1.7683060 0.6894663    22.97222      .sigma
## 57  3.62093430 0.8250542  1.7678624 0.7127824    22.97222      .sigma
## 58  4.05244578 0.8214438  1.7673789 0.7373732    22.97222      .sigma
## 59 -3.89862540 0.8471386  6.2829261 0.5499197    16.91670 (Intercept)
## 60 -3.55323116 0.8473352  5.0646474 0.5499181    18.19415 (Intercept)
## 61 -3.20172214 0.8475661  4.1499639 0.5499164    19.18003 (Intercept)
## 62 -2.84310260 0.8477943  3.4591194 0.5499145    19.95628 (Intercept)
## 63 -2.47610405 0.8479510  2.9359657 0.5499133    20.58176 (Intercept)
## 64 -2.09917760 0.8479419  2.5409791 0.5499133    21.09939 (Intercept)
## 65 -1.71055410 0.8476799  2.2463525 0.5499154    21.54105 (Intercept)
## 66 -1.30836273 0.8471463  2.0326343 0.5499196    21.93105 (Intercept)
## 67 -0.89069537 0.8464498  1.8865555 0.5499252    22.28868 (Intercept)
## 68 -0.45541171 0.8458301  1.8000518 0.5499301    22.63047 (Intercept)
## 69  0.00000000 0.8455722  1.7706463 0.5499322    22.97222 (Intercept)
## 70  0.45198446 0.8458264  1.7996069 0.5499302    23.31136 (Intercept)
## 71  0.88743896 0.8464444  1.8856755 0.5499252    23.65311 (Intercept)
## 72  1.30523154 0.8471413  2.0312748 0.5499197    24.01056 (Intercept)
## 73  1.70753392 0.8476768  2.2444327 0.5499154    24.40025 (Intercept)
## 74  2.09625397 0.8479409  2.5383759 0.5499133    24.84143 (Intercept)
## 75  2.47326291 0.8479517  2.9325026 0.5499133    25.35836 (Intercept)
## 76  2.84033113 0.8477959  3.4545440 0.5499145    25.98287 (Intercept)
## 77  3.19900953 0.8475680  4.1439257 0.5499163    26.75777 (Intercept)
## 78  3.55056880 0.8473372  5.0566141 0.5499181    27.74178 (Intercept)
## 79  3.89600661 0.8471399  6.2722013 0.5499197    29.01661 (Intercept)
library(lattice)
xyplot(pr03, aspect = 1.3)

confint(pr03)
##                  2.5 %     97.5 %
## .sig01       0.6335658  1.1821040
## .sig02       1.0957893  3.5562919
## .sigma       0.4858454  0.6294535
## (Intercept) 21.2666274 24.6778176
confint(pr03, level = 0.99)
##                  0.5 %     99.5 %
## .sig01       0.5825413  1.3301551
## .sig02       0.9700367  4.7401291
## .sigma       0.4682700  0.6584123
## (Intercept) 20.4255688 25.5188739
splom(pr03)

ranef(model3)
## $plate
##   (Intercept)
## a  0.80454704
## b  0.80454704
## c  0.18167191
## d  0.33739069
## e  0.02595313
## f -0.44120322
## g -1.37551591
## h  0.80454704
## i -0.75264078
## j -0.75264078
## k  0.96026582
## l  0.49310948
## m  1.42742217
## n  0.49310948
## o  0.96026582
## p  0.02595313
## q -0.28548443
## r -0.28548443
## s -1.37551591
## t  0.96026582
## u -0.90835956
## v -0.28548443
## w -0.59692200
## x -1.21979713
## 
## $sample
##   (Intercept)
## A  2.18705797
## B -1.01047615
## C  1.93789946
## D -0.09689497
## E -0.01384214
## F -3.00374417
str(ranef(model3))
## List of 2
##  $ plate :'data.frame':  24 obs. of  1 variable:
##   ..$ (Intercept): num [1:24] 0.805 0.805 0.182 0.337 0.026 ...
##  $ sample:'data.frame':  6 obs. of  1 variable:
##   ..$ (Intercept): num [1:6] 2.1871 -1.0105 1.9379 -0.0969 -0.0138 ...
##  - attr(*, "class")= chr "ranef.mer"
dotplot(ranef(model3, postVar = TRUE))
## Warning in ranef.merMod(model3, postVar = TRUE): 'postVar' is deprecated:
## please use 'condVar' instead
## $plate

## 
## $sample

qqmath(ranef(model3, postVar=TRUE))
## Warning in ranef.merMod(model3, postVar = TRUE): 'postVar' is deprecated:
## please use 'condVar' instead
## $plate

## 
## $sample

str(Pastes)
## 'data.frame':    60 obs. of  4 variables:
##  $ strength: num  62.8 62.6 60.1 62.3 62.7 63.1 60 61.4 57.5 56.9 ...
##  $ batch   : Factor w/ 10 levels "A","B","C","D",..: 1 1 1 1 1 1 2 2 2 2 ...
##  $ cask    : Factor w/ 3 levels "a","b","c": 1 1 2 2 3 3 1 1 2 2 ...
##  $ sample  : Factor w/ 30 levels "A:a","A:b","A:c",..: 1 1 2 2 3 3 4 4 5 5 ...
summary(Pastes)
##     strength         batch    cask       sample  
##  Min.   :54.20   A      : 6   a:20   A:a    : 2  
##  1st Qu.:57.50   B      : 6   b:20   A:b    : 2  
##  Median :59.30   C      : 6   c:20   A:c    : 2  
##  Mean   :60.05   D      : 6          B:a    : 2  
##  3rd Qu.:62.88   E      : 6          B:b    : 2  
##  Max.   :66.00   F      : 6          B:c    : 2  
##                  (Other):24          (Other):48
xtabs(~ batch + sample, Pastes, drop = TRUE, sparse = TRUE)
## 10 x 30 sparse Matrix of class "dgCMatrix"
##    [[ suppressing 30 column names 'A:a', 'A:b', 'A:c' ... ]]
##                                                              
## A 2 2 2 . . . . . . . . . . . . . . . . . . . . . . . . . . .
## B . . . 2 2 2 . . . . . . . . . . . . . . . . . . . . . . . .
## C . . . . . . 2 2 2 . . . . . . . . . . . . . . . . . . . . .
## D . . . . . . . . . 2 2 2 . . . . . . . . . . . . . . . . . .
## E . . . . . . . . . . . . 2 2 2 . . . . . . . . . . . . . . .
## F . . . . . . . . . . . . . . . 2 2 2 . . . . . . . . . . . .
## G . . . . . . . . . . . . . . . . . . 2 2 2 . . . . . . . . .
## H . . . . . . . . . . . . . . . . . . . . . 2 2 2 . . . . . .
## I . . . . . . . . . . . . . . . . . . . . . . . . 2 2 2 . . .
## J . . . . . . . . . . . . . . . . . . . . . . . . . . . 2 2 2
xtabs(~ cask + batch, Pastes)
##     batch
## cask A B C D E F G H I J
##    a 2 2 2 2 2 2 2 2 2 2
##    b 2 2 2 2 2 2 2 2 2 2
##    c 2 2 2 2 2 2 2 2 2 2
Pastes$sample <- with(Pastes, factor(batch:cask))

(model4 <- lmer(strength ~ 1 + (1|sample) + (1|batch), Pastes, REML=FALSE))
## Linear mixed model fit by maximum likelihood  ['lmerMod']
## Formula: strength ~ 1 + (1 | sample) + (1 | batch)
##    Data: Pastes
##       AIC       BIC    logLik  deviance  df.resid 
##  255.9945  264.3718 -123.9972  247.9945        56 
## Random effects:
##  Groups   Name        Std.Dev.
##  sample   (Intercept) 2.9041  
##  batch    (Intercept) 1.0951  
##  Residual             0.8234  
## Number of obs: 60, groups:  sample, 30; batch, 10
## Fixed Effects:
## (Intercept)  
##       60.05
(model4a <- lmer(strength ~ 1 + (1|sample), Pastes, REML=FALSE))
## Linear mixed model fit by maximum likelihood  ['lmerMod']
## Formula: strength ~ 1 + (1 | sample)
##    Data: Pastes
##       AIC       BIC    logLik  deviance  df.resid 
##  254.4017  260.6847 -124.2008  248.4017        57 
## Random effects:
##  Groups   Name        Std.Dev.
##  sample   (Intercept) 3.1037  
##  Residual             0.8234  
## Number of obs: 60, groups:  sample, 30
## Fixed Effects:
## (Intercept)  
##       60.05
anova(model4a, model4)
## Data: Pastes
## Models:
## model4a: strength ~ 1 + (1 | sample)
## model4: strength ~ 1 + (1 | sample) + (1 | batch)
##         Df    AIC    BIC logLik deviance  Chisq Chi Df Pr(>Chisq)
## model4a  3 254.40 260.69 -124.2   248.40                         
## model4   4 255.99 264.37 -124.0   247.99 0.4072      1     0.5234
pr04 <- profile(model4)
pr04
##          .zeta   .sig01       .sig02    .sigma (Intercept)        .par
## 1  -4.02919334 1.641803 1.757994e+00 0.8977597    60.05333      .sig01
## 2  -3.53448855 1.748506 1.725281e+00 0.8752994    60.05333      .sig01
## 3  -3.03540030 1.865427 1.685340e+00 0.8593031    60.05333      .sig01
## 4  -2.53250465 1.994525 1.636329e+00 0.8476893    60.05333      .sig01
## 5  -2.02604908 2.138075 1.575504e+00 0.8391970    60.05333      .sig01
## 6  -1.51610053 2.298797 1.498746e+00 0.8330053    60.05333      .sig01
## 7  -1.00273559 2.479951 1.399611e+00 0.8285480    60.05333      .sig01
## 8  -0.48787048 2.684729 1.267767e+00 0.8254239    60.05333      .sig01
## 9   0.00000000 2.904078 1.095060e+00 0.8234076    60.05333      .sig01
## 10  0.06030165 2.933118 1.068973e+00 0.8232106    60.05333      .sig01
## 11  0.48747981 3.152467 8.354983e-01 0.8220903    60.05333      .sig01
## 12  0.89469514 3.386340 4.341610e-01 0.8214003    60.05333      .sig01
## 13  1.31900891 3.647924 1.642801e-07 0.8206861    60.05333      .sig01
## 14  1.76895182 3.928712 8.071144e-08 0.8201976    60.05333      .sig01
## 15  2.19306530 4.212947 0.000000e+00 0.8199954    60.05333      .sig01
## 16  2.60941550 4.518193 1.642521e-07 0.8199647    60.05333      .sig01
## 17  3.02216129 4.852116 5.574730e-06 0.8200519    60.05333      .sig01
## 18  3.43255512 5.220600 0.000000e+00 0.8202209    60.05333      .sig01
## 19  3.84110953 5.629553 1.639669e-07 0.8204443    60.05333      .sig01
## 20 -0.63814884 3.103679 0.000000e+00 0.8234076    60.05333      .sig02
## 21 -0.47239338 3.038796 5.433365e-01 0.8234075    60.05333      .sig02
## 22 -0.11278654 2.930001 9.855538e-01 0.8234075    60.05333      .sig02
## 23  0.00000000 2.904078 1.095060e+00 0.8234076    60.05333      .sig02
## 24  0.01165767 2.901600 1.106010e+00 0.8234077    60.05333      .sig02
## 25  0.13136637 2.878217 1.215516e+00 0.8234081    60.05333      .sig02
## 26  0.61459405 2.816115 1.632162e+00 0.8234076    60.05333      .sig02
## 27  1.06372733 2.791920 2.024871e+00 0.8234076    60.05333      .sig02
## 28  1.48108698 2.787499 2.423116e+00 0.8234075    60.05333      .sig02
## 29  1.88409174 2.793391 2.857722e+00 0.8234076    60.05333      .sig02
## 30  2.27809830 2.804811 3.348901e+00 0.8234076    60.05333      .sig02
## 31  2.66547853 2.818808 3.916697e+00 0.8234076    60.05333      .sig02
## 32  3.04746455 2.833440 4.584286e+00 0.8234076    60.05333      .sig02
## 33  3.42476567 2.847437 5.380294e+00 0.8234072    60.05333      .sig02
## 34  3.79783131 2.860005 6.341207e+00 0.8234074    60.05333      .sig02
## 35 -3.98723581 2.938020 1.095060e+00 0.5304859    60.05333      .sigma
## 36 -3.49135556 2.935626 1.095060e+00 0.5563558    60.05333      .sigma
## 37 -2.99400652 2.932880 1.095060e+00 0.5846046    60.05333      .sigma
## 38 -2.49509669 2.929713 1.095060e+00 0.6155479    60.05333      .sigma
## 39 -1.99452698 2.926039 1.095060e+00 0.6495556    60.05333      .sigma
## 40 -1.49219407 2.921753 1.095060e+00 0.6870627    60.05333      .sigma
## 41 -0.98805474 2.916720 1.095059e+00 0.7285780    60.05333      .sigma
## 42 -0.48327976 2.910786 1.095060e+00 0.7745879    60.05333      .sigma
## 43  0.00000000 2.904078 1.095060e+00 0.8234076    60.05333      .sigma
## 44  0.07682017 2.902904 1.095060e+00 0.8316416    60.05333      .sigma
## 45  0.50760409 2.895697 1.095059e+00 0.8804613    60.05333      .sigma
## 46  0.92213889 2.887608 1.095060e+00 0.9320780    60.05333      .sigma
## 47  1.33629036 2.878161 1.095060e+00 0.9887913    60.05333      .sigma
## 48  1.74934993 2.867088 1.095060e+00 1.0511619    60.05333      .sigma
## 49  2.16131960 2.854039 1.095060e+00 1.1199357    60.05333      .sigma
## 50  2.57217092 2.838572 1.095060e+00 1.1959706    60.05333      .sigma
## 51  2.98187781 2.820130 1.095059e+00 1.2802620    60.05333      .sigma
## 52  3.39041533 2.797995 1.095060e+00 1.3739676    60.05333      .sigma
## 53  3.79775995 2.771241 1.095060e+00 1.4784368    60.05333      .sigma
## 54 -3.71631976 2.904078 3.672042e+00 0.8234075    56.54837 (Intercept)
## 55 -3.33599332 2.904078 3.102214e+00 0.8234075    57.15082 (Intercept)
## 56 -2.94953822 2.904078 2.630150e+00 0.8234076    57.66199 (Intercept)
## 57 -2.55625757 2.904078 2.236411e+00 0.8234075    58.10336 (Intercept)
## 58 -2.15536070 2.904078 1.907184e+00 0.8234076    58.49186 (Intercept)
## 59 -1.74594742 2.904078 1.633622e+00 0.8234076    58.84108 (Intercept)
## 60 -1.32698609 2.904078 1.411768e+00 0.8234075    59.16230 (Intercept)
## 61 -0.89728335 2.904078 1.242926e+00 0.8234076    59.46536 (Intercept)
## 62 -0.45544115 2.904078 1.133834e+00 0.8234075    59.75936 (Intercept)
## 63  0.00000000 2.904078 1.095060e+00 0.8234076    60.05333 (Intercept)
## 64  0.45312920 2.904078 1.133444e+00 0.8234075    60.34580 (Intercept)
## 65  0.89504959 2.904078 1.242207e+00 0.8234076    60.63978 (Intercept)
## 66  1.32481060 2.904078 1.410763e+00 0.8234075    60.94277 (Intercept)
## 67  1.74382384 2.904078 1.632354e+00 0.8234076    61.26388 (Intercept)
## 68  2.15328334 2.904078 1.905645e+00 0.8234076    61.61293 (Intercept)
## 69  2.55422149 2.904078 2.234568e+00 0.8234076    62.00119 (Intercept)
## 70  2.94753909 2.904078 2.627945e+00 0.8234076    62.44225 (Intercept)
## 71  3.33402736 2.904078 3.099563e+00 0.8234075    62.95301 (Intercept)
## 72  3.71438360 2.904078 3.668828e+00 0.8234076    63.55493 (Intercept)
library(lattice)
xyplot(pr04, aspect = 1.3)

confint(pr04)
##                  2.5 %    97.5 %
## .sig01       2.1579337  4.053589
## .sig02       0.0000000  2.946591
## .sigma       0.6520234  1.085448
## (Intercept) 58.6636504 61.443016
confint(pr04, level = 0.99)
##                  0.5 %    99.5 %
## .sig01       1.9829151  4.492471
## .sig02       0.0000000  3.776505
## .sigma       0.6103545  1.196684
## (Intercept) 58.0829453 62.023723
splom(pr04)

ranef(model4)
## $sample
##     (Intercept)
## A:a  1.92558677
## A:b  0.48355090
## A:c  2.11785822
## B:a  0.83229519
## B:b -2.53245517
## B:c  0.15934512
## C:a -2.43608072
## C:b  2.75524839
## C:c  3.76467350
## D:a -3.07689823
## D:b -2.11554099
## D:c  4.46975614
## E:a -3.60073081
## E:b -4.22561302
## E:c -0.66859122
## F:a  3.66437104
## F:b -1.57502594
## F:c -0.08492222
## G:a  2.44305764
## G:b -0.15260692
## G:c -2.60406790
## H:a -1.58067150
## H:b  4.47587914
## H:c  3.37031831
## I:a -4.66730442
## I:b  4.17718223
## I:c -2.31197917
## J:a -0.79391737
## J:b -0.40937447
## J:c -1.80334248
## 
## $batch
##   (Intercept)
## A  0.64367893
## B -0.21908349
## C  0.58066819
## D -0.10275597
## E -1.20786739
## F  0.28500242
## G -0.04459222
## H  0.89087491
## I -0.39842175
## J -0.42750363
str(ranef(model4))
## List of 2
##  $ sample:'data.frame':  30 obs. of  1 variable:
##   ..$ (Intercept): num [1:30] 1.926 0.484 2.118 0.832 -2.532 ...
##  $ batch :'data.frame':  10 obs. of  1 variable:
##   ..$ (Intercept): num [1:10] 0.644 -0.219 0.581 -0.103 -1.208 ...
##  - attr(*, "class")= chr "ranef.mer"
dotplot(ranef(model4, postVar = TRUE))
## Warning in ranef.merMod(model4, postVar = TRUE): 'postVar' is deprecated:
## please use 'condVar' instead
## $sample

## 
## $batch

qqmath(ranef(model4, postVar=TRUE))
## Warning in ranef.merMod(model4, postVar = TRUE): 'postVar' is deprecated:
## please use 'condVar' instead
## $sample

## 
## $batch

pr04a <- profile(model4a)
pr04a
##          .zeta   .sig01    .sigma (Intercept)        .par
## 1  -3.64513976 2.015095 0.8710798    60.05333      .sig01
## 2  -3.19290153 2.115684 0.8587105    60.05333      .sig01
## 3  -2.73883044 2.224168 0.8491433    60.05333      .sig01
## 4  -2.28303876 2.341610 0.8416941    60.05333      .sig01
## 5  -1.82557607 2.469215 0.8358877    60.05333      .sig01
## 6  -1.36645284 2.608366 0.8313796    60.05333      .sig01
## 7  -0.90569450 2.760649 0.8279113    60.05333      .sig01
## 8  -0.44419079 2.927572 0.8252865    60.05333      .sig01
## 9   0.00000000 3.103679 0.8234076    60.05333      .sig01
## 10  0.07420110 3.134716 0.8231466    60.05333      .sig01
## 11  0.47437374 3.310822 0.8219653    60.05333      .sig01
## 12  0.86085303 3.496107 0.8211398    60.05333      .sig01
## 13  1.24693170 3.697954 0.8205702    60.05333      .sig01
## 14  1.63207449 3.918072 0.8202099    60.05333      .sig01
## 15  2.01628706 4.158698 0.8200180    60.05333      .sig01
## 16  2.39955258 4.422381 0.8199596    60.05333      .sig01
## 17  2.78185490 4.712043 0.8200046    60.05333      .sig01
## 18  3.16317792 5.031046 0.8201277    60.05333      .sig01
## 19  3.54350595 5.383264 0.8203073    60.05333      .sig01
## 20 -3.66186562 3.134023 0.5472150    60.05333      .sigma
## 21 -3.20598215 3.131785 0.5722652    60.05333      .sigma
## 22 -2.74893711 3.129241 0.5994584    60.05333      .sigma
## 23 -2.29066484 3.126334 0.6290572    60.05333      .sigma
## 24 -1.83109520 3.122999 0.6613657    60.05333      .sigma
## 25 -1.37015548 3.119151 0.6967369    60.05333      .sigma
## 26 -0.90781542 3.114688 0.7355790    60.05333      .sigma
## 27 -0.44496857 3.109496 0.7782792    60.05333      .sigma
## 28  0.00000000 3.103679 0.8234076    60.05333      .sigma
## 29  0.07682014 3.102581 0.8316416    60.05333      .sigma
## 30  0.47642433 3.096362 0.8767700    60.05333      .sigma
## 31  0.86225156 3.089440 0.9243176    60.05333      .sigma
## 32  1.24776053 3.081450 0.9762031    60.05333      .sigma
## 33  1.63239072 3.072200 1.0328690    60.05333      .sigma
## 34  2.01614257 3.061441 1.0948969    60.05333      .sigma
## 35  2.39899396 3.048868 1.1629499    60.05333      .sigma
## 36  2.78092434 3.034100 1.2377886    60.05333      .sigma
## 37  3.16191388 3.016661 1.3202882    60.05333      .sigma
## 38  3.54194361 2.995950 1.4114574    60.05333      .sigma
## 39 -3.66716408 3.908055 0.8234076    57.67845 (Intercept)
## 40 -3.27207835 3.729535 0.8234076    57.98534 (Intercept)
## 41 -2.87418831 3.576871 0.8234076    58.27536 (Intercept)
## 42 -2.47337343 3.447962 0.8234076    58.55146 (Intercept)
## 43 -2.06951050 3.341116 0.8234076    58.81631 (Intercept)
## 44 -1.66247367 3.255019 0.8234076    59.07235 (Intercept)
## 45 -1.25213464 3.188702 0.8234076    59.32190 (Intercept)
## 46 -0.83836269 3.141529 0.8234076    59.56714 (Intercept)
## 47 -0.42102495 3.113184 0.8234076    59.81024 (Intercept)
## 48  0.00000000 3.103679 0.8234076    60.05333 (Intercept)
## 49  0.42040682 3.113157 0.8234076    60.29607 (Intercept)
## 50  0.83775082 3.141473 0.8234075    60.53917 (Intercept)
## 51  1.25152791 3.188619 0.8234076    60.78441 (Intercept)
## 52  1.66187191 3.254907 0.8234076    61.03394 (Intercept)
## 53  2.06891350 3.340974 0.8234076    61.28998 (Intercept)
## 54  2.47278102 3.447788 0.8234076    61.55481 (Intercept)
## 55  2.87360029 3.576664 0.8234076    61.83089 (Intercept)
## 56  3.27149455 3.729291 0.8234076    62.12089 (Intercept)
## 57  3.66658432 3.907772 0.8234076    62.42775 (Intercept)
library(lattice)
xyplot(pr04a, aspect = 1.3)

confint(pr04a)
##                  2.5 %    97.5 %
## .sig01       2.4306377  4.122011
## .sigma       0.6520207  1.085448
## (Intercept) 58.8861831 61.220484
confint(pr04a, level = 0.99)
##                  0.5 %    99.5 %
## .sig01       2.2651645  4.552495
## .sigma       0.6103609  1.196701
## (Intercept) 58.4822254 61.624441
splom(pr04a)

ranef(model4a)
## $sample
##     (Intercept)
## A:a  2.55669114
## A:b  1.10768482
## A:c  2.74989198
## B:a  0.62468272
## B:b -2.75633201
## B:c -0.05152022
## C:a -1.88692822
## C:b  3.32949450
## C:c  4.34379892
## D:a -3.19103390
## D:b -2.22502969
## D:c  4.39209913
## E:a -4.78494084
## E:b -5.41284358
## E:c -1.83862801
## F:a  3.95739724
## F:b -1.30732569
## F:c  0.18998083
## G:a  2.41179050
## G:b -0.19642086
## G:c -2.65973158
## H:a -0.72772317
## H:b  5.35810334
## H:c  4.24719850
## I:a -5.07474210
## I:b  3.81249661
## I:c -2.70803179
## J:a -1.21072527
## J:b -0.82432359
## J:c -2.22502969
str(ranef(model4a))
## List of 1
##  $ sample:'data.frame':  30 obs. of  1 variable:
##   ..$ (Intercept): num [1:30] 2.557 1.108 2.75 0.625 -2.756 ...
##  - attr(*, "class")= chr "ranef.mer"
dotplot(ranef(model4a, postVar = TRUE))
## Warning in ranef.merMod(model4a, postVar = TRUE): 'postVar' is deprecated:
## please use 'condVar' instead
## $sample

qqmath(ranef(model4a, postVar=TRUE))
## Warning in ranef.merMod(model4a, postVar = TRUE): 'postVar' is deprecated:
## please use 'condVar' instead
## $sample

str(InstEval)
## 'data.frame':    73421 obs. of  7 variables:
##  $ s      : Factor w/ 2972 levels "1","2","3","4",..: 1 1 1 1 2 2 3 3 3 3 ...
##  $ d      : Factor w/ 1128 levels "1","6","7","8",..: 525 560 832 1068 62 406 3 6 19 75 ...
##  $ studage: Ord.factor w/ 4 levels "2"<"4"<"6"<"8": 1 1 1 1 1 1 1 1 1 1 ...
##  $ lectage: Ord.factor w/ 6 levels "1"<"2"<"3"<"4"<..: 2 1 2 2 1 1 1 1 1 1 ...
##  $ service: Factor w/ 2 levels "0","1": 1 2 1 2 1 1 2 1 1 1 ...
##  $ dept   : Factor w/ 14 levels "15","5","10",..: 14 5 14 12 2 2 13 3 3 3 ...
##  $ y      : int  5 2 5 3 2 4 4 5 5 4 ...
xtabs(~ y, InstEval)
## y
##     1     2     3     4     5 
## 10186 12951 17609 16921 15754
(model5 <- lmer(y ~ 1 + (1|s) + (1|d)+(1|dept:service), InstEval, REML=FALSE))
## Linear mixed model fit by maximum likelihood  ['lmerMod']
## Formula: y ~ 1 + (1 | s) + (1 | d) + (1 | dept:service)
##    Data: InstEval
##       AIC       BIC    logLik  deviance  df.resid 
##  237663.3  237709.3 -118826.6  237653.3     73416 
## Random effects:
##  Groups       Name        Std.Dev.
##  s            (Intercept) 0.3247  
##  d            (Intercept) 0.5124  
##  dept:service (Intercept) 0.1101  
##  Residual                 1.1768  
## Number of obs: 73421, groups:  s, 2972; d, 1128; dept:service, 28
## Fixed Effects:
## (Intercept)  
##       3.255
ranef(model5)
## $s
##        (Intercept)
## 1     1.479558e-01
## 2    -4.640765e-02
## 3     3.190478e-01
## 4     2.477672e-01
## 5     4.003869e-02
## 6     1.152942e-01
## 7     4.696395e-01
## 8     1.872891e-01
## 9     4.221157e-01
## 10    3.088335e-01
## 11   -3.264982e-02
## 12   -2.378291e-01
## 13    1.119334e-01
## 14    1.538647e-01
## 15    3.173446e-01
## 16    1.317343e-01
## 17   -2.357918e-02
## 18   -4.042113e-02
## 19   -2.160224e-02
## 20    3.218401e-01
## 21   -1.629951e-01
## 22    6.464568e-01
## 23    4.251941e-01
## 24   -1.827652e-01
## 25   -1.248677e-01
## 26    2.748793e-01
## 27    2.533187e-03
## 28    3.984152e-01
## 29    4.834440e-01
## 30    2.546294e-01
## 31    6.371636e-02
## 32   -1.547806e-01
## 33   -2.158216e-01
## 34   -9.950627e-02
## 35   -4.844240e-01
## 36    3.626951e-01
## 37    3.378640e-01
## 38    3.254166e-01
## 39    2.400115e-01
## 40    1.443721e-02
## 41    1.556329e-01
## 42   -4.475789e-01
## 43   -8.485258e-02
## 44   -1.710101e-02
## 45   -8.018243e-02
## 46   -1.641236e-02
## 47    4.837594e-01
## 48    2.194738e-01
## 49    2.752717e-01
## 50   -1.063766e-01
## 51    1.524026e-01
## 52    1.989288e-01
## 53    4.291441e-01
## 54   -2.021065e-01
## 55    3.003342e-01
## 56   -4.207670e-01
## 57   -4.400752e-01
## 58    8.831501e-02
## 59   -2.538611e-01
## 60    3.290818e-02
## 61    2.855285e-01
## 62    3.812364e-01
## 63    6.277453e-02
## 64    2.103735e-01
## 65    3.261628e-01
## 66    6.328381e-02
## 67   -2.116618e-01
## 68   -2.528048e-01
## 69    2.294022e-01
## 70   -2.941338e-01
## 71   -5.699918e-03
## 72    1.027520e-01
## 73   -4.146669e-01
## 74    1.133888e-01
## 75    2.384956e-01
## 76    7.768673e-02
## 77   -2.829046e-01
## 78   -1.708340e-02
## 79    3.671644e-01
## 80   -4.514029e-02
## 81    1.418521e-01
## 82    2.688315e-01
## 83   -1.710763e-02
## 84    5.537982e-02
## 85   -1.395846e-01
## 86   -1.488193e-01
## 87   -1.232709e-01
## 88   -1.073697e-01
## 89   -2.447386e-01
## 90   -2.561890e-02
## 91    1.693184e-01
## 92    4.185995e-01
## 93    1.987764e-01
## 94   -2.148903e-01
## 95    5.790346e-01
## 96    8.759331e-02
## 97   -1.173931e-01
## 98   -2.558076e-01
## 99   -1.426815e-01
## 100   5.878465e-01
## 101   8.347451e-02
## 102  -3.545077e-01
## 103  -8.928818e-03
## 104  -3.671065e-01
## 105  -2.229795e-01
## 106   2.123600e-01
## 107  -2.451628e-01
## 108  -5.330930e-01
## 109  -2.144376e-03
## 110   5.165007e-02
## 111   3.203331e-03
## 112   3.341380e-01
## 113  -2.051154e-01
## 114  -1.214108e-01
## 115   1.529433e-01
## 116  -3.637440e-01
## 117  -2.890014e-01
## 118   2.318498e-01
## 119  -4.535820e-01
## 120  -3.737443e-02
## 121   4.072724e-01
## 122   2.253116e-01
## 123  -4.580437e-01
## 124  -6.643964e-02
## 125   2.269570e-02
## 126   1.069245e-01
## 127  -3.003418e-01
## 128  -2.522871e-01
## 129   5.731324e-02
## 130   1.598125e-01
## 131   8.090485e-02
## 132  -3.103447e-01
## 133  -6.851211e-02
## 134  -2.101207e-01
## 135  -5.406760e-01
## 136  -9.584350e-02
## 137  -4.858965e-01
## 138  -2.592273e-01
## 139   1.373013e-01
## 140   1.846216e-01
## 141  -3.590723e-01
## 142   5.895761e-01
## 143   2.720308e-01
## 144   1.712056e-01
## 145   6.169809e-02
## 146   3.830437e-01
## 147  -3.405520e-01
## 148  -5.286101e-02
## 149  -1.813111e-01
## 150   2.492766e-01
## 151  -1.966040e-01
## 152   6.737356e-02
## 153   4.165016e-02
## 154  -6.846998e-02
## 155   1.380529e-01
## 156   6.992926e-02
## 157   2.676621e-01
## 158  -1.637622e-01
## 159   2.335118e-01
## 160   2.323763e-01
## 161   6.681551e-02
## 162   5.610910e-01
## 163   2.234818e-01
## 164   5.501604e-02
## 165  -2.793003e-02
## 166  -3.390087e-01
## 167   6.073126e-02
## 168   9.331824e-02
## 169   2.208527e-01
## 170   2.041078e-02
## 171  -2.660735e-02
## 172  -3.957298e-01
## 173  -3.884689e-01
## 174  -1.245950e-02
## 175  -1.673689e-01
## 176  -1.843267e-03
## 177   7.807779e-02
## 178  -2.516627e-01
## 179   2.395707e-01
## 180  -4.206796e-01
## 181   2.914109e-01
## 182  -1.134251e-01
## 183   5.503630e-01
## 184   2.086190e-01
## 185  -6.420357e-02
## 186   3.249719e-01
## 187  -3.405153e-02
## 188  -4.849835e-02
## 189   5.225984e-02
## 190  -2.174387e-01
## 191   7.075080e-02
## 192   5.867758e-01
## 193   3.930642e-01
## 194  -1.281085e-01
## 195   2.422439e-01
## 196   7.641826e-02
## 197   1.726378e-03
## 198  -3.078167e-01
## 199  -8.246112e-02
## 200  -4.455327e-02
## 201  -3.301457e-01
## 202  -2.868238e-01
## 203  -1.354910e-02
## 204  -8.157043e-02
## 205   1.497248e-01
## 206   3.749131e-01
## 207  -1.554863e-01
## 208   7.978221e-02
## 209  -2.943852e-01
## 210   5.237852e-02
## 211  -6.672052e-02
## 212   6.937449e-03
## 213   1.987878e-01
## 214  -9.553266e-02
## 215   1.153908e-03
## 216   1.640714e-01
## 217  -1.096124e-01
## 218  -3.129595e-01
## 219   2.903378e-02
## 220  -1.165416e-01
## 221   3.917346e-04
## 222   2.427842e-01
## 223   1.233419e-01
## 224   4.593862e-01
## 225   3.980726e-01
## 226   1.685658e-01
## 227   7.111409e-02
## 228  -2.684762e-01
## 229   6.330965e-02
## 230  -1.408943e-01
## 231   1.497610e-01
## 232   3.389175e-01
## 233  -9.890812e-02
## 234   1.760429e-01
## 235  -1.786171e-01
## 236  -1.539370e-01
## 237   2.675880e-01
## 238  -1.963610e-01
## 239  -8.788019e-03
## 240   2.228847e-01
## 241  -2.822519e-01
## 242  -1.171699e-01
## 243  -4.312884e-01
## 244  -3.261999e-01
## 245   1.995523e-01
## 246  -3.948438e-01
## 247  -5.355347e-01
## 248   3.502045e-01
## 249   4.903693e-02
## 250   1.857616e-01
## 251  -1.429378e-01
## 252   4.238065e-01
## 253  -3.169264e-01
## 254  -3.767641e-01
## 255   4.889459e-01
## 256  -9.452284e-02
## 257  -2.169966e-02
## 258  -1.353318e-01
## 259  -1.698882e-01
## 260   1.763136e-01
## 261   1.266350e-01
## 262   8.300512e-02
## 263   7.986063e-02
## 264   1.243356e-01
## 265  -3.533825e-01
## 266   4.858311e-01
## 267  -2.541894e-01
## 268   4.352971e-01
## 269  -1.554920e-01
## 270   2.875400e-01
## 271   2.570904e-01
## 272  -1.048275e-01
## 273  -1.044908e-01
## 274   3.975559e-02
## 275   6.447665e-01
## 276   2.823281e-01
## 277   1.774360e-01
## 278  -8.562749e-02
## 279  -3.643348e-01
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## 1963  0.4626869629
## 1964 -0.0158244988
## 1965 -0.1134480552
## 1966  0.3460272559
## 1968  0.5522269381
## 1975  0.2324298362
## 1977 -0.7561162108
## 1978  0.2138766543
## 1979  0.3560850560
## 1982  0.6610713137
## 1983 -0.0543169193
## 1984 -0.9368168136
## 1988 -0.2371639175
## 1992 -0.3468164373
## 1993 -0.2202326154
## 1995 -0.6298531318
## 1998  0.1420511009
## 2000  0.3517873244
## 2002  0.1568014079
## 2004 -0.0378217967
## 2006 -0.3437917974
## 2007  0.2040370775
## 2008 -0.4756952241
## 2009 -0.6308516482
## 2013 -1.3661256867
## 2015  0.6456482549
## 2016  0.3358156075
## 2019  0.4851685206
## 2021 -0.8828832328
## 2023 -0.3464028296
## 2025  0.2437990627
## 2026  0.2024829418
## 2029 -0.7816989647
## 2032 -0.0890912078
## 2034  0.0012235615
## 2036 -0.2165347669
## 2037  0.1463723463
## 2043  0.2563951230
## 2045 -0.1836026244
## 2048  0.3726868931
## 2050 -0.1968835763
## 2052 -0.1596322461
## 2053 -0.1041117384
## 2055 -0.0658052115
## 2057  0.2352719479
## 2058 -0.0306085851
## 2059 -0.2069777543
## 2061 -0.2306134232
## 2063  0.4578007294
## 2064 -0.4676986522
## 2067  0.1097701758
## 2068 -0.4028403581
## 2070 -0.1581321598
## 2074  0.6075162547
## 2075  0.0679459692
## 2076  0.8123256074
## 2077 -0.8208190652
## 2079 -0.4504562424
## 2083  0.0875173913
## 2084  0.7657098791
## 2085 -0.3230280961
## 2086  0.3145985898
## 2087  0.1982164484
## 2090  0.4740702157
## 2092  0.2368786943
## 2096  0.3058506822
## 2097 -0.3246366170
## 2098 -0.3217226590
## 2099  0.2301150044
## 2100  0.4510687775
## 2102 -0.4170248890
## 2103  0.6294361048
## 2105 -0.0343452483
## 2108 -0.1473285202
## 2110  0.4284072733
## 2112 -0.8592063821
## 2113 -0.0968451583
## 2114  0.4469678945
## 2115 -0.3506694070
## 2116  0.3251825131
## 2117 -0.3264270086
## 2118  0.1244679196
## 2121  0.1262382025
## 2123 -0.0165813628
## 2125  0.6912409059
## 2128  0.0839049142
## 2129  0.2138710562
## 2132  0.1527100556
## 2138 -0.7027494322
## 2139 -0.1205870079
## 2141 -0.0446897317
## 2143  0.4309140125
## 2145 -0.4995377632
## 2146  0.2068463235
## 2147 -0.6566093011
## 2149 -0.3318309770
## 2152 -0.1013042122
## 2153 -0.3866900387
## 2156 -0.5624424705
## 2157  0.5823814224
## 2160 -0.2910484462
## 
## $`dept:service`
##       (Intercept)
## 15:0 -0.047839371
## 15:1  0.154602219
## 5:0   0.048720782
## 5:1   0.072421837
## 10:0 -0.165662341
## 10:1  0.057190792
## 12:0  0.023753762
## 12:1 -0.007547317
## 6:0   0.038234172
## 6:1  -0.189710197
## 7:0   0.085236770
## 7:1  -0.027862281
## 4:0   0.092246120
## 4:1   0.066657203
## 8:0   0.027147038
## 8:1   0.097782509
## 9:0   0.053327097
## 9:1  -0.164455636
## 14:0  0.056097413
## 14:1 -0.154664430
## 1:0   0.009956489
## 1:1   0.019533672
## 3:0   0.013598001
## 3:1   0.035621174
## 11:0  0.071008802
## 11:1 -0.182675133
## 2:0   0.018398875
## 2:1  -0.101118021
str(ranef(model5))
## List of 3
##  $ s           :'data.frame':    2972 obs. of  1 variable:
##   ..$ (Intercept): num [1:2972] 0.148 -0.0464 0.319 0.2478 0.04 ...
##  $ d           :'data.frame':    1128 obs. of  1 variable:
##   ..$ (Intercept): num [1:1128] 0.419 -0.472 0.742 -0.587 0.305 ...
##  $ dept:service:'data.frame':    28 obs. of  1 variable:
##   ..$ (Intercept): num [1:28] -0.0478 0.1546 0.0487 0.0724 -0.1657 ...
##  - attr(*, "class")= chr "ranef.mer"
dotplot(ranef(model5, postVar = TRUE))
## Warning in ranef.merMod(model5, postVar = TRUE): 'postVar' is deprecated:
## please use 'condVar' instead
## $s

## 
## $d

## 
## $`dept:service`

qqmath(ranef(model5, postVar=TRUE))
## Warning in ranef.merMod(model5, postVar = TRUE): 'postVar' is deprecated:
## please use 'condVar' instead
## $s

## 
## $d

## 
## $`dept:service`

model5a <- lmer(y ~ 1 + (1|s) + (1|d), InstEval, REML=0)
anova(model5a,model5)
## Data: InstEval
## Models:
## model5a: y ~ 1 + (1 | s) + (1 | d)
## model5: y ~ 1 + (1 | s) + (1 | d) + (1 | dept:service)
##         Df    AIC    BIC  logLik deviance  Chisq Chi Df Pr(>Chisq)    
## model5a  4 237786 237823 -118889   237778                             
## model5   5 237663 237709 -118827   237653 124.43      1  < 2.2e-16 ***
## ---
## Signif. codes:  0 '***' 0.001 '**' 0.01 '*' 0.05 '.' 0.1 ' ' 1