data<-read.csv("C:/R_work/ECMO903.csv")
head(data)
Unit.number Name Sex Age Date Year Holiday Insertion.time
1 `08243022 이영순 1 49 20090511 2009 1 1
2 13034861 윤기정 1 77 20090518 2009 1 NA
3 14186610 임지현 1 33 20090722 2009 1 1
4 14340394 이수맹 0 67 20091007 2009 1 1
5 10870744 김창길 0 56 20100212 2010 1 0
6 11071670 이영익 0 67 20100217 2010 1 0
ECMO.duration Death Height Weight BMI Diagnosis Smoking CAD CVA PAD
1 8 1 NA NA NA Myocarditis 2 1 1 1
2 24 0 NA NA NA ACS 2 1 1 1
3 8 2 NA NA NA ARDS 2 1 1 1
4 15 0 NA NA NA ACS 0 0 1 1
5 5 0 1.65 68 29.76 ACS 2 1 1 1
6 2 0 1.70 65 26.37 ARDS 2 1 1 1
DM HBP Indication Mode CA OHCA CPR.duration CA.ECMO.Time EKG Weaning
1 1 1 0 0 1 NA NA NA 2 0
2 1 0 0 0 1 NA NA NA 2 0
3 1 1 1 1 1 NA NA NA 2 0
4 0 0 0 0 0 1 37 37 0 0
5 1 0 0 0 0 1 25 25 0 1
6 1 1 1 1 0 1 210 210 2 1
Vent Intu.day HD ICU.stay CRRT CRRT.duration CAG PCI GCS Bleeding
1 0 8 30 11 0 8 1 1 15 1
2 0 27 31 31 1 NA 0 1 5 1
3 0 27 28 28 1 NA 1 1 15 0
4 0 17 17 17 0 13 0 0 3 1
5 0 5 5 5 0 3 0 0 3 1
6 0 3 43 3 1 NA 1 1 12 1
Tamponade Pulmo AKI Liver.failure MOF Sepsis Stroke Leg.ischemia WBC
1 1 1 0 1 1 1 1 1 16400
2 1 1 0 1 1 1 1 1 5230
3 1 0 1 1 0 0 1 1 18030
4 1 0 0 1 0 1 1 1 9670
5 1 1 0 1 1 1 1 1 10930
6 1 1 0 1 1 0 1 1 17950
Hct PLT Sodium K HCO3 BUN Cr Glucose Albumin Total..bilirubin CRP
1 43.0 248 143.2 3.9 15.9 20.1 2.3 184 4.7 1.1 0.31
2 30.1 154 143.2 3.1 18.0 6.3 1.0 153 4.2 0.5 1.03
3 37.8 55 148.9 3.4 23.3 22.3 1.3 150 3.1 1.1 8.22
4 36.0 54 144.8 3.4 9.0 20.1 1.5 56 2.2 0.5 13.34
5 44.8 293 136.8 3.2 13.4 15.9 1.5 200 2.5 0.6 0.07
6 22.3 70 143.2 6.5 10.9 48.9 2.5 488 1.6 0.3 23.27
D.dimer CK.MB Troponin PRC FFP PC Cryo
1 2.29 30.95 3.050 5 3 72 0
2 NA 3.97 0.298 22 7 61 0
3 11.28 219.50 1.300 4 19 40 0
4 1.03 8.91 0.088 35 9 136 0
5 NA 3.47 0.020 10 0 18 0
6 0.44 4.38 0.036 24 5 42 0
str(data)
'data.frame': 78 obs. of 65 variables:
$ Unit.number : Factor w/ 78 levels "`08243022","10279578",..: 1 9 14 15 3 4 68 5 11 17 ...
$ Name : Factor w/ 76 levels "강신윤","강신훈",..: 44 37 56 42 13 45 38 30 17 62 ...
$ Sex : int 1 1 1 0 0 0 0 0 0 1 ...
$ Age : int 49 77 33 67 56 67 76 48 67 69 ...
$ Date : int 20090511 20090518 20090722 20091007 20100212 20100217 20100223 20100317 20100323 20100408 ...
$ Year : int 2009 2009 2009 2009 2010 2010 2010 2010 2010 2010 ...
$ Holiday : int 1 1 1 1 1 1 1 1 1 1 ...
$ Insertion.time : int 1 NA 1 1 0 0 0 1 1 0 ...
$ ECMO.duration : num 8 24 8 15 5 2 5 1 14 6 ...
$ Death : int 1 0 2 0 0 0 0 0 0 0 ...
$ Height : num NA NA NA NA 1.65 1.7 1.64 1.75 1.65 1.55 ...
$ Weight : num NA NA NA NA 68 65 68 75 60 53 ...
$ BMI : num NA NA NA NA 29.8 ...
$ Diagnosis : Factor w/ 9 levels "ACS","ARDS","Drug Intoxication",..: 5 1 2 1 1 2 1 1 1 1 ...
$ Smoking : int 2 2 2 0 2 2 1 0 2 2 ...
$ CAD : int 1 1 1 0 1 1 1 1 1 1 ...
$ CVA : int 1 1 1 1 1 1 1 1 1 1 ...
$ PAD : int 1 1 1 1 1 1 1 1 1 1 ...
$ DM : int 1 1 1 0 1 1 0 0 0 0 ...
$ HBP : int 1 0 1 0 0 1 0 0 0 1 ...
$ Indication : int 0 0 1 0 0 1 0 0 0 0 ...
$ Mode : int 0 0 1 0 0 1 0 0 0 0 ...
$ CA : int 1 1 1 0 0 0 1 0 1 0 ...
$ OHCA : int NA NA NA 1 1 1 NA 0 NA 0 ...
$ CPR.duration : int NA NA NA 37 25 210 NA 30 NA 20 ...
$ CA.ECMO.Time : int NA NA NA 37 25 210 NA 240 NA 540 ...
$ EKG : int 2 2 2 0 0 2 2 2 2 2 ...
$ Weaning : int 0 0 0 0 1 1 0 1 0 1 ...
$ Vent : int 0 0 0 0 0 0 0 0 0 0 ...
$ Intu.day : Factor w/ 29 levels "","0","1","10",..: 27 17 17 10 24 19 28 12 11 25 ...
$ HD : int 30 31 28 17 5 43 12 2 20 6 ...
$ ICU.stay : int 11 31 28 17 5 3 12 2 20 6 ...
$ CRRT : int 0 1 1 0 0 1 1 1 1 0 ...
$ CRRT.duration : int 8 NA NA 13 3 NA NA NA NA 5 ...
$ CAG : int 1 0 1 0 0 1 0 1 0 1 ...
$ PCI : int 1 1 1 0 0 1 0 1 1 1 ...
$ GCS : int 15 5 15 3 3 12 4 3 3 3 ...
$ Bleeding : int 1 1 0 1 1 1 1 0 0 1 ...
$ Tamponade : int 1 1 1 1 1 1 1 1 1 1 ...
$ Pulmo : int 1 1 0 0 1 1 1 1 1 1 ...
$ AKI : int 0 0 1 0 0 0 1 1 1 0 ...
$ Liver.failure : int 1 1 1 1 1 1 1 1 1 1 ...
$ MOF : int 1 1 0 0 1 1 0 0 0 1 ...
$ Sepsis : int 1 1 0 1 1 0 1 1 0 1 ...
$ Stroke : int 1 1 1 1 1 1 1 1 1 1 ...
$ Leg.ischemia : int 1 1 1 1 1 1 1 1 1 1 ...
$ WBC : int 16400 5230 18030 9670 10930 17950 6790 20410 18230 21500 ...
$ Hct : num 43 30.1 37.8 36 44.8 22.3 40.1 32.1 26.5 30.2 ...
$ PLT : int 248 154 55 54 293 70 173 203 334 235 ...
$ Sodium : num 143 143 149 145 137 ...
$ K : num 3.9 3.1 3.4 3.4 3.2 6.5 3.8 6.6 4.1 5.4 ...
$ HCO3 : num 15.9 18 23.3 9 13.4 10.9 14.9 10.5 12.7 12.5 ...
$ BUN : num 20.1 6.3 22.3 20.1 15.9 48.9 15.8 54.6 49.9 40.7 ...
$ Cr : num 2.3 1 1.3 1.5 1.5 2.5 0.9 3.9 1.3 1.6 ...
$ Glucose : int 184 153 150 56 200 488 178 256 230 208 ...
$ Albumin : num 4.7 4.2 3.1 2.2 2.5 1.6 3.8 3 4.1 2.8 ...
$ Total..bilirubin: num 1.1 0.5 1.1 0.5 0.6 0.3 1.1 0.6 0.5 1 ...
$ CRP : num 0.31 1.03 8.22 13.34 0.07 ...
$ D.dimer : num 2.29 NA 11.28 1.03 NA ...
$ CK.MB : num 30.95 3.97 219.5 8.91 3.47 ...
$ Troponin : num 3.05 0.298 1.3 0.088 0.02 ...
$ PRC : int 5 22 4 35 10 24 14 9 42 10 ...
$ FFP : int 3 7 19 9 0 5 0 0 5 0 ...
$ PC : int 72 61 40 136 18 42 46 0 170 54 ...
$ Cryo : int 0 0 0 0 0 0 0 0 0 0 ...
summary(data)
Unit.number Name Sex Age
`08243022: 1 이영순 : 2 Min. :0.00 Min. : 2.0
10279578 : 1 이영화 : 2 1st Qu.:0.00 1st Qu.:49.2
10870744 : 1 강신윤 : 1 Median :0.00 Median :63.0
11071670 : 1 강신훈 : 1 Mean :0.41 Mean :59.6
11144868 : 1 강정애 : 1 3rd Qu.:1.00 3rd Qu.:72.8
11620651 : 1 김기수 : 1 Max. :1.00 Max. :86.0
(Other) :72 (Other):70
Date Year Holiday Insertion.time
Min. :20090511 Min. :2009 Min. :0.000 Min. :0.000
1st Qu.:20110644 1st Qu.:2011 1st Qu.:1.000 1st Qu.:0.000
Median :20121022 Median :2012 Median :1.000 Median :0.000
Mean :20120930 Mean :2012 Mean :0.859 Mean :0.416
3rd Qu.:20131028 3rd Qu.:2013 3rd Qu.:1.000 3rd Qu.:1.000
Max. :20140804 Max. :2014 Max. :1.000 Max. :1.000
NA's :1
ECMO.duration Death Height Weight
Min. : 0.2 Min. :0.000 Min. :0.91 Min. :11.5
1st Qu.: 2.0 1st Qu.:0.000 1st Qu.:1.60 1st Qu.:55.0
Median : 6.0 Median :0.000 Median :1.65 Median :60.0
Mean : 7.4 Mean :0.372 Mean :1.64 Mean :60.8
3rd Qu.:10.8 3rd Qu.:1.000 3rd Qu.:1.70 3rd Qu.:68.0
Max. :24.0 Max. :2.000 Max. :1.83 Max. :80.0
NA's :11 NA's :9
BMI Diagnosis Smoking CAD
Min. :12.5 ACS :34 Min. :0.00 Min. :0.000
1st Qu.:24.6 ARDS :14 1st Qu.:0.00 1st Qu.:1.000
Median :27.1 PTE : 8 Median :2.00 Median :1.000
Mean :26.8 Myocarditis : 7 Mean :1.32 Mean :0.795
3rd Qu.:29.1 Pump failure: 7 3rd Qu.:2.00 3rd Qu.:1.000
Max. :33.5 VF, VT : 4 Max. :2.00 Max. :1.000
NA's :11 (Other) : 4
CVA PAD DM HBP
Min. :0.000 Min. :1 Min. :0.000 Min. :0.00
1st Qu.:1.000 1st Qu.:1 1st Qu.:1.000 1st Qu.:0.00
Median :1.000 Median :1 Median :1.000 Median :1.00
Mean :0.949 Mean :1 Mean :0.756 Mean :0.59
3rd Qu.:1.000 3rd Qu.:1 3rd Qu.:1.000 3rd Qu.:1.00
Max. :1.000 Max. :1 Max. :1.000 Max. :1.00
Indication Mode CA OHCA
Min. :0.000 Min. :0.000 Min. :0.000 Min. :0.00
1st Qu.:0.000 1st Qu.:0.000 1st Qu.:0.000 1st Qu.:1.00
Median :0.000 Median :0.000 Median :0.000 Median :1.00
Mean :0.192 Mean :0.192 Mean :0.487 Mean :0.88
3rd Qu.:0.000 3rd Qu.:0.000 3rd Qu.:1.000 3rd Qu.:1.00
Max. :1.000 Max. :1.000 Max. :1.000 Max. :1.00
NA's :38
CPR.duration CA.ECMO.Time EKG Weaning
Min. : 2.0 Min. : 0.0 Min. :0.00 Min. :0.000
1st Qu.: 10.8 1st Qu.: 19.5 1st Qu.:1.00 1st Qu.:0.000
Median : 25.0 Median : 39.0 Median :2.00 Median :1.000
Mean : 30.6 Mean : 92.3 Mean :1.53 Mean :0.603
3rd Qu.: 40.2 3rd Qu.: 48.5 3rd Qu.:2.00 3rd Qu.:1.000
Max. :210.0 Max. :1080.0 Max. :2.00 Max. :2.000
NA's :38 NA's :38
Vent Intu.day HD ICU.stay
Min. :0.0000 2 : 7 Min. : 0.00 Min. : 0.0
1st Qu.:0.0000 1 : 6 1st Qu.: 4.25 1st Qu.: 4.0
Median :0.0000 3 : 6 Median :18.50 Median :10.0
Mean :0.0385 4 : 6 Mean :22.59 Mean :12.9
3rd Qu.:0.0000 6 : 6 3rd Qu.:34.00 3rd Qu.:19.0
Max. :1.0000 10 : 4 Max. :86.00 Max. :44.0
(Other):43
CRRT CRRT.duration CAG PCI
Min. :0.000 Min. : 1.00 Min. :0.0 Min. :0.000
1st Qu.:0.000 1st Qu.: 3.00 1st Qu.:0.0 1st Qu.:0.000
Median :1.000 Median : 5.00 Median :0.5 Median :1.000
Mean :0.603 Mean : 6.39 Mean :0.5 Mean :0.718
3rd Qu.:1.000 3rd Qu.: 8.00 3rd Qu.:1.0 3rd Qu.:1.000
Max. :1.000 Max. :20.00 Max. :1.0 Max. :1.000
NA's :47
GCS Bleeding Tamponade Pulmo
Min. : 3.00 Min. :0.000 Min. :0.000 Min. :0.000
1st Qu.: 4.00 1st Qu.:0.000 1st Qu.:1.000 1st Qu.:1.000
Median : 7.00 Median :1.000 Median :1.000 Median :1.000
Mean : 8.26 Mean :0.667 Mean :0.949 Mean :0.872
3rd Qu.:13.00 3rd Qu.:1.000 3rd Qu.:1.000 3rd Qu.:1.000
Max. :15.00 Max. :1.000 Max. :1.000 Max. :1.000
AKI Liver.failure MOF Sepsis
Min. :0.000 Min. :0.000 Min. :0.000 Min. :0.000
1st Qu.:0.000 1st Qu.:1.000 1st Qu.:1.000 1st Qu.:1.000
Median :1.000 Median :1.000 Median :1.000 Median :1.000
Mean :0.577 Mean :0.949 Mean :0.769 Mean :0.859
3rd Qu.:1.000 3rd Qu.:1.000 3rd Qu.:1.000 3rd Qu.:1.000
Max. :1.000 Max. :1.000 Max. :1.000 Max. :1.000
Stroke Leg.ischemia WBC Hct
Min. :0.000 Min. :0.000 Min. : 610 Min. :18.1
1st Qu.:1.000 1st Qu.:1.000 1st Qu.: 8808 1st Qu.:30.7
Median :1.000 Median :1.000 Median :12330 Median :35.1
Mean :0.962 Mean :0.949 Mean :13493 Mean :34.8
3rd Qu.:1.000 3rd Qu.:1.000 3rd Qu.:16602 3rd Qu.:40.0
Max. :1.000 Max. :1.000 Max. :48290 Max. :53.8
PLT Sodium K HCO3
Min. : 17.0 Min. :128 Min. :2.40 Min. : 5.9
1st Qu.: 97.5 1st Qu.:139 1st Qu.:3.62 1st Qu.:10.9
Median :144.5 Median :141 Median :4.00 Median :13.9
Mean :162.1 Mean :141 Mean :4.20 Mean :14.8
3rd Qu.:215.5 3rd Qu.:144 3rd Qu.:4.50 3rd Qu.:18.1
Max. :414.0 Max. :157 Max. :7.60 Max. :32.3
NA's :2
BUN Cr Glucose Albumin
Min. : 6.3 Min. :0.40 Min. : 50 Min. :1.40
1st Qu.:15.6 1st Qu.:0.90 1st Qu.:136 1st Qu.:2.40
Median :20.4 Median :1.20 Median :182 Median :2.95
Mean :25.7 Mean :1.44 Mean :203 Mean :3.03
3rd Qu.:32.2 3rd Qu.:1.50 3rd Qu.:247 3rd Qu.:3.77
Max. :88.9 Max. :8.30 Max. :488 Max. :4.70
NA's :2
Total..bilirubin CRP D.dimer CK.MB
Min. :0.30 Min. : 0.02 Min. : 0.05 Min. : 0.70
1st Qu.:0.50 1st Qu.: 0.43 1st Qu.: 1.21 1st Qu.: 3.01
Median :0.90 Median : 2.52 Median : 4.84 Median : 16.52
Mean :1.24 Mean : 7.05 Mean : 9.84 Mean : 42.42
3rd Qu.:1.40 3rd Qu.:13.34 3rd Qu.:15.34 3rd Qu.: 40.55
Max. :7.10 Max. :30.25 Max. :45.00 Max. :300.00
NA's :1 NA's :1 NA's :26 NA's :9
Troponin PRC FFP PC
Min. : 0.010 Min. : 0.0 Min. : 0 Min. : 0.0
1st Qu.: 0.034 1st Qu.: 8.0 1st Qu.: 0 1st Qu.: 10.0
Median : 0.232 Median : 18.0 Median : 7 Median : 32.0
Mean : 1.430 Mean : 23.9 Mean :11 Mean : 47.1
3rd Qu.: 1.225 3rd Qu.: 31.0 3rd Qu.:17 3rd Qu.: 60.0
Max. :17.190 Max. :150.0 Max. :72 Max. :240.0
NA's :12 NA's :1 NA's :1 NA's :1
Cryo
Min. : 0.0
1st Qu.: 0.0
Median : 0.0
Mean : 1.7
3rd Qu.: 0.0
Max. :20.0
NA's :1
data1=data[data$Death<2,-c(1,2,5)]
data1$Survive=ifelse(data1$Death==0,0,1)
table(data1$Death)
0 1
52 23
library(compareGroups)
data1$Sex=ifelse(data1$Sex==1,"Female","Male")
data1$Holiday=ifelse(data1$Holiday==1,"Not Holiday","Holiday")
data1$Insertion.time=ifelse(data1$Insertion.time==1,"Emergency","Elective")
data1$Death=ifelse(data1$Death==1,"Survivor","Non-survivor")
data1$Smoking=ifelse(data1$Smoking==1,"No","Yes")
data1$CAD=ifelse(data1$CAD==1,"No","Yes")
data1$CVA=ifelse(data1$CVA==1,"No","Yes")
data1$PAD=ifelse(data1$PAD==1,"No","Yes")
data1$DM=ifelse(data1$DM==1,"No","Yes")
data1$HBP=ifelse(data1$HBP==1,"No","Yes")
data1$Indication=ifelse(data1$Indication==1,"Respiratory","Cardiology")
data1$Mode=ifelse(data1$Mode==1,"VV","VA")
data1$CA=ifelse(data1$CA==1,"No","Yes")
data1$OHCA=ifelse(data1$OHCA==1,"IHCA","OHCA")
data1$EKG=ifelse(data1$EKG==0,"Asystole",
ifelse(data1$EKG==1,"PEA","ETC"))
data1$Weaning=ifelse(data1$Weaning==1,"Fail","Success")
data1$Vent=ifelse(data1$Vent==1,"No","Yes")
data1$CRRT=ifelse(data1$CRRT==1,"No","Yes")
data1$CAG=ifelse(data1$CAG==1,"No","Yes")
data1$PCI=ifelse(data1$PCI==1,"No","Yes")
data1$Bleeding=ifelse(data1$Bleeding==1,"No","Yes")
data1$Tamponade=ifelse(data1$Tamponade==1,"No","Yes")
data1$Pulmo=ifelse(data1$Pulmo==1,"No","Yes")
data1$AKI=ifelse(data1$AKI==1,"No","Yes")
data1$Liver.failure=ifelse(data1$Liver.failure==1,"No","Yes")
data1$MOF=ifelse(data1$MOF==1,"No","Yes")
data1$Sepsis=ifelse(data1$Sepsis==1,"No","Yes")
data1$Stroke=ifelse(data1$Stroke==1,"No","Yes")
data1$Leg.ischemia=ifelse(data1$Leg.ischemia==1,"No","Yes")
mosaicplot(~Year+Death,data=data1,color=TRUE,xlab="Year",ylab="Survival",main="Distribution of ECMO")
res=compareGroups(Survive~.,data=data1)
res
-------- Summary of results by groups of 'Survive'---------
var N p.value method selection
1 Sex 75 0.878 categorical ALL
2 Age 75 0.018** continuous normal ALL
3 Year 75 0.015** continuous normal ALL
4 Holiday 75 1.000 categorical ALL
5 Insertion.time 74 0.673 categorical ALL
6 ECMO.duration 75 0.241 continuous normal ALL
7 Death 75 <0.001** categorical ALL
8 Height 65 0.708 continuous normal ALL
9 Weight 67 0.980 continuous normal ALL
10 BMI 65 0.694 continuous normal ALL
11 Diagnosis 75 0.237 categorical ALL
12 Smoking 75 0.728 categorical ALL
13 CAD 75 0.369 categorical ALL
14 CVA 75 1.000 categorical ALL
15 PAD 75 . categorical ALL
16 DM 75 0.180 categorical ALL
17 HBP 75 0.126 categorical ALL
18 Indication 75 0.750 categorical ALL
19 Mode 75 0.750 categorical ALL
20 CA 75 0.083* categorical ALL
21 OHCA 39 1.000 categorical ALL
22 CPR.duration 39 0.055* continuous normal ALL
23 CA.ECMO.Time 39 0.076* continuous normal ALL
24 EKG 75 0.026** categorical ALL
25 Weaning 75 <0.001** categorical ALL
26 Vent 75 0.026** categorical ALL
27 HD 75 <0.001** continuous normal ALL
28 ICU.stay 75 0.001** continuous normal ALL
29 CRRT 75 0.218 categorical ALL
30 CRRT.duration 29 0.175 continuous normal ALL
31 CAG 75 0.281 categorical ALL
32 PCI 75 0.600 categorical ALL
33 GCS 75 0.001** continuous normal ALL
34 Bleeding 75 0.535 categorical ALL
35 Tamponade 75 1.000 categorical ALL
36 Pulmo 75 0.713 categorical ALL
37 AKI 75 0.308 categorical ALL
38 Liver.failure 75 0.306 categorical ALL
39 MOF 75 0.026** categorical ALL
40 Sepsis 75 1.000 categorical ALL
41 Stroke 75 0.091* categorical ALL
42 Leg.ischemia 75 0.582 categorical ALL
43 WBC 75 0.558 continuous normal ALL
44 Hct 75 0.583 continuous normal ALL
45 PLT 75 0.432 continuous normal ALL
46 Sodium 75 0.404 continuous normal ALL
47 K 75 0.015** continuous normal ALL
48 HCO3 73 0.042** continuous normal ALL
49 BUN 75 0.014** continuous normal ALL
50 Cr 75 0.003** continuous normal ALL
51 Glucose 73 0.437 continuous normal ALL
52 Albumin 75 0.668 continuous normal ALL
53 Total..bilirubin 74 0.499 continuous normal ALL
54 CRP 74 0.187 continuous normal ALL
55 D.dimer 49 0.796 continuous normal ALL
56 CK.MB 66 0.784 continuous normal ALL
57 Troponin 64 0.522 continuous normal ALL
58 PRC 74 0.187 continuous normal ALL
59 FFP 74 0.338 continuous normal ALL
60 PC 74 0.074* continuous normal ALL
61 Cryo 74 0.753 continuous normal ALL
-----
Signif. codes: 0 '**' 0.05 '*' 0.1 ' ' 1
createTable(res)
--------Summary descriptives table by 'Survive'---------
_________________________________________________________
0 1 p.overall
N=52 N=23
<U+00AF><U+00AF><U+00AF><U+00AF><U+00AF><U+00AF><U+00AF><U+00AF><U+00AF><U+00AF><U+00AF><U+00AF><U+00AF><U+00AF><U+00AF><U+00AF><U+00AF><U+00AF><U+00AF><U+00AF><U+00AF><U+00AF><U+00AF><U+00AF><U+00AF><U+00AF><U+00AF><U+00AF><U+00AF><U+00AF><U+00AF><U+00AF><U+00AF><U+00AF><U+00AF><U+00AF><U+00AF><U+00AF><U+00AF><U+00AF><U+00AF><U+00AF><U+00AF><U+00AF><U+00AF><U+00AF><U+00AF><U+00AF><U+00AF><U+00AF><U+00AF><U+00AF><U+00AF><U+00AF><U+00AF><U+00AF><U+00AF>
Sex: 0.878
Female 20 (38.5%) 10 (43.5%)
Male 32 (61.5%) 13 (56.5%)
Age 63.8 (13.6) 52.5 (19.6) 0.018
Year 2012 (1.40) 2013 (1.43) 0.015
Holiday: 1.000
Holiday 8 (15.4%) 3 (13.0%)
Not Holiday 44 (84.6%) 20 (87.0%)
Insertion.time: 0.673
Elective 29 (56.9%) 15 (65.2%)
Emergency 22 (43.1%) 8 (34.8%)
ECMO.duration 6.75 (6.51) 8.36 (4.84) 0.241
Death: <0.001
Non-survivor 52 (100%) 0 (0.00%)
Survivor 0 (0.00%) 23 (100%)
Height 1.64 (0.08) 1.63 (0.19) 0.708
Weight 60.6 (8.69) 60.5 (14.3) 0.980
BMI 26.7 (3.50) 26.3 (3.96) 0.694
Diagnosis: 0.237
ACS 27 (51.9%) 6 (26.1%)
ARDS 8 (15.4%) 5 (21.7%)
Drug Intoxication 1 (1.92%) 0 (0.00%)
LA myxoma 1 (1.92%) 0 (0.00%)
Myocarditis 2 (3.85%) 4 (17.4%)
PTE 4 (7.69%) 4 (17.4%)
Pump failure 5 (9.62%) 2 (8.70%)
Trauma 1 (1.92%) 1 (4.35%)
VF, VT 3 (5.77%) 1 (4.35%)
Smoking: 0.728
No 7 (13.5%) 4 (17.4%)
Yes 45 (86.5%) 19 (82.6%)
CAD: 0.369
No 40 (76.9%) 20 (87.0%)
Yes 12 (23.1%) 3 (13.0%)
CVA: 1.000
No 49 (94.2%) 22 (95.7%)
Yes 3 (5.77%) 1 (4.35%)
PAD: No 52 (100%) 23 (100%) .
DM: 0.180
No 36 (69.2%) 20 (87.0%)
Yes 16 (30.8%) 3 (13.0%)
HBP: 0.126
No 27 (51.9%) 17 (73.9%)
Yes 25 (48.1%) 6 (26.1%)
Indication: 0.750
Cardiology 43 (82.7%) 18 (78.3%)
Respiratory 9 (17.3%) 5 (21.7%)
Mode: 0.750
VA 43 (82.7%) 18 (78.3%)
VV 9 (17.3%) 5 (21.7%)
CA: 0.083
No 21 (40.4%) 15 (65.2%)
Yes 31 (59.6%) 8 (34.8%)
OHCA: 1.000
IHCA 27 (87.1%) 7 (87.5%)
OHCA 4 (12.9%) 1 (12.5%)
CPR.duration 33.8 (36.7) 16.9 (15.0) 0.055
CA.ECMO.Time 109 (221) 35.2 (16.3) 0.076
EKG: 0.026
Asystole 15 (28.8%) 1 (4.35%)
ETC 33 (63.5%) 21 (91.3%)
PEA 4 (7.69%) 1 (4.35%)
Weaning: <0.001
Fail 44 (84.6%) 0 (0.00%)
Success 8 (15.4%) 23 (100%)
Vent: 0.026
No 0 (0.00%) 3 (13.0%)
Yes 52 (100%) 20 (87.0%)
HD 14.7 (15.6) 40.4 (18.1) <0.001
ICU.stay 9.75 (9.43) 18.9 (10.1) 0.001
CRRT: 0.218
No 29 (55.8%) 17 (73.9%)
Yes 23 (44.2%) 6 (26.1%)
CRRT.duration 5.78 (4.65) 9.17 (5.00) 0.175
CAG: 0.281
No 23 (44.2%) 14 (60.9%)
Yes 29 (55.8%) 9 (39.1%)
PCI: 0.600
No 36 (69.2%) 18 (78.3%)
Yes 16 (30.8%) 5 (21.7%)
GCS 6.81 (4.24) 10.9 (4.50) 0.001
Bleeding: 0.535
No 33 (63.5%) 17 (73.9%)
Yes 19 (36.5%) 6 (26.1%)
Tamponade: 1.000
No 49 (94.2%) 22 (95.7%)
Yes 3 (5.77%) 1 (4.35%)
Pulmo: 0.713
No 45 (86.5%) 21 (91.3%)
Yes 7 (13.5%) 2 (8.70%)
AKI: 0.308
No 28 (53.8%) 16 (69.6%)
Yes 24 (46.2%) 7 (30.4%)
Liver.failure: 0.306
No 48 (92.3%) 23 (100%)
Yes 4 (7.69%) 0 (0.00%)
MOF: 0.026
No 36 (69.2%) 22 (95.7%)
Yes 16 (30.8%) 1 (4.35%)
Sepsis: 1.000
No 46 (88.5%) 20 (87.0%)
Yes 6 (11.5%) 3 (13.0%)
Stroke: 0.091
No 52 (100%) 21 (91.3%)
Yes 0 (0.00%) 2 (8.70%)
Leg.ischemia: 0.582
No 50 (96.2%) 21 (91.3%)
Yes 2 (3.85%) 2 (8.70%)
WBC 13751 (8254) 12786 (5610) 0.558
Hct 34.4 (7.31) 35.5 (7.86) 0.583
PLT 167 (100) 151 (77.1) 0.432
Sodium 142 (5.23) 141 (5.78) 0.404
K 4.36 (1.07) 3.93 (0.44) 0.015
HCO3 13.7 (5.02) 17.0 (6.54) 0.042
BUN 28.7 (17.7) 20.4 (10.3) 0.014
Cr 1.62 (1.23) 1.04 (0.41) 0.003
Glucose 207 (108) 192 (59.6) 0.437
Albumin 2.99 (0.88) 3.07 (0.78) 0.668
Total..bilirubin 1.19 (1.36) 1.42 (1.26) 0.499
CRP 6.12 (7.73) 9.41 (10.5) 0.187
D.dimer 9.86 (12.2) 8.94 (11.4) 0.796
CK.MB 36.2 (47.2) 31.4 (71.1) 0.784
Troponin 1.53 (3.48) 1.07 (2.12) 0.522
PRC 26.5 (27.6) 19.2 (18.3) 0.187
FFP 11.9 (14.2) 8.91 (11.3) 0.338
PC 53.6 (62.1) 33.4 (33.3) 0.074
Cryo 1.87 (4.83) 1.55 (3.54) 0.753
<U+00AF><U+00AF><U+00AF><U+00AF><U+00AF><U+00AF><U+00AF><U+00AF><U+00AF><U+00AF><U+00AF><U+00AF><U+00AF><U+00AF><U+00AF><U+00AF><U+00AF><U+00AF><U+00AF><U+00AF><U+00AF><U+00AF><U+00AF><U+00AF><U+00AF><U+00AF><U+00AF><U+00AF><U+00AF><U+00AF><U+00AF><U+00AF><U+00AF><U+00AF><U+00AF><U+00AF><U+00AF><U+00AF><U+00AF><U+00AF><U+00AF><U+00AF><U+00AF><U+00AF><U+00AF><U+00AF><U+00AF><U+00AF><U+00AF><U+00AF><U+00AF><U+00AF><U+00AF><U+00AF><U+00AF><U+00AF><U+00AF>
out=lm(Survive~Age+EKG+GCS+K+HCO3+BUN+Cr,data=data1)
anova(out)
Analysis of Variance Table
Response: Survive
Df Sum Sq Mean Sq F value Pr(>F)
Age 1 1.30 1.303 8.25 0.0055 **
EKG 2 0.95 0.475 3.01 0.0564 .
GCS 1 1.63 1.626 10.29 0.0021 **
K 1 0.86 0.861 5.45 0.0227 *
HCO3 1 0.21 0.213 1.35 0.2500
BUN 1 0.29 0.286 1.81 0.1831
Cr 1 0.02 0.017 0.11 0.7410
Residuals 64 10.11 0.158
---
Signif. codes: 0 '***' 0.001 '**' 0.01 '*' 0.05 '.' 0.1 ' ' 1
confint(out)
2.5 % 97.5 %
(Intercept) -0.09000 1.324465
Age -0.01372 -0.001852
EKGETC -0.06618 0.463505
EKGPEA -0.28030 0.620177
GCS 0.01068 0.052544
K -0.19917 0.067662
HCO3 -0.01018 0.029433
BUN -0.01406 0.002781
Cr -0.11749 0.164317
out2=lm(Survive~Age+GCS+K,data=data1)
anova(out2)
Analysis of Variance Table
Response: Survive
Df Sum Sq Mean Sq F value Pr(>F)
Age 1 1.62 1.619 10.2 0.00205 **
GCS 1 2.31 2.306 14.6 0.00028 ***
K 1 0.81 0.806 5.1 0.02697 *
Residuals 71 11.22 0.158
---
Signif. codes: 0 '***' 0.001 '**' 0.01 '*' 0.05 '.' 0.1 ' ' 1
confint(out2)
2.5 % 97.5 %
(Intercept) 0.41150 1.619705
Age -0.01448 -0.003158
GCS 0.01696 0.056448
K -0.21032 -0.013095
summary(out)
Call:
lm(formula = Survive ~ Age + EKG + GCS + K + HCO3 + BUN + Cr,
data = data1)
Residuals:
Min 1Q Median 3Q Max
-0.6108 -0.3021 -0.0819 0.2735 0.7925
Coefficients:
Estimate Std. Error t value Pr(>|t|)
(Intercept) 0.61723 0.35402 1.74 0.0860 .
Age -0.00778 0.00297 -2.62 0.0109 *
EKGETC 0.19866 0.13257 1.50 0.1389
EKGPEA 0.16994 0.22538 0.75 0.4536
GCS 0.03161 0.01048 3.02 0.0037 **
K -0.06576 0.06678 -0.98 0.3285
HCO3 0.00963 0.00991 0.97 0.3353
BUN -0.00564 0.00421 -1.34 0.1857
Cr 0.02341 0.07053 0.33 0.7410
---
Signif. codes: 0 '***' 0.001 '**' 0.01 '*' 0.05 '.' 0.1 ' ' 1
Residual standard error: 0.397 on 64 degrees of freedom
(2 observations deleted due to missingness)
Multiple R-squared: 0.342, Adjusted R-squared: 0.26
F-statistic: 4.16 on 8 and 64 DF, p-value: 0.000475
summary(out2)
Call:
lm(formula = Survive ~ Age + GCS + K, data = data1)
Residuals:
Min 1Q Median 3Q Max
-0.642 -0.248 -0.122 0.317 0.856
Coefficients:
Estimate Std. Error t value Pr(>|t|)
(Intercept) 1.01560 0.30297 3.35 0.00129 **
Age -0.00882 0.00284 -3.11 0.00272 **
GCS 0.03670 0.00990 3.71 0.00041 ***
K -0.11171 0.04946 -2.26 0.02697 *
---
Signif. codes: 0 '***' 0.001 '**' 0.01 '*' 0.05 '.' 0.1 ' ' 1
Residual standard error: 0.397 on 71 degrees of freedom
Multiple R-squared: 0.297, Adjusted R-squared: 0.267
F-statistic: 9.98 on 3 and 71 DF, p-value: 1.43e-05
out=glm(Survive~Age+EKG+GCS+K+HCO3+BUN+Cr,family=binomial,data=data1)
summary(out)
Call:
glm(formula = Survive ~ Age + EKG + GCS + K + HCO3 + BUN + Cr,
family = binomial, data = data1)
Deviance Residuals:
Min 1Q Median 3Q Max
-1.499 -0.665 -0.168 0.277 2.365
Coefficients:
Estimate Std. Error z value Pr(>|z|)
(Intercept) 3.0202 3.0746 0.98 0.3259
Age -0.0692 0.0277 -2.49 0.0126 *
EKGETC 2.4616 1.3212 1.86 0.0624 .
EKGPEA 1.7998 1.8365 0.98 0.3271
GCS 0.2876 0.0962 2.99 0.0028 **
K -0.5689 0.5481 -1.04 0.2992
HCO3 0.0412 0.0724 0.57 0.5689
BUN -0.0535 0.0369 -1.45 0.1470
Cr -1.1460 0.8622 -1.33 0.1838
---
Signif. codes: 0 '***' 0.001 '**' 0.01 '*' 0.05 '.' 0.1 ' ' 1
(Dispersion parameter for binomial family taken to be 1)
Null deviance: 89.355 on 72 degrees of freedom
Residual deviance: 52.918 on 64 degrees of freedom
(2 observations deleted due to missingness)
AIC: 70.92
Number of Fisher Scoring iterations: 6
exp(coef(out))
(Intercept) Age EKGETC EKGPEA GCS K
20.4957 0.9331 11.7234 6.0484 1.3332 0.5661
HCO3 BUN Cr
1.0421 0.9479 0.3179
confint(out)
2.5 % 97.5 %
(Intercept) -3.0326 9.35893
Age -0.1320 -0.02174
EKGETC 0.2193 5.74244
EKGPEA -2.0306 5.69066
GCS 0.1182 0.50296
K -1.7263 0.46948
HCO3 -0.1025 0.18679
BUN -0.1324 0.01500
Cr -3.0337 0.43597
exp(confint(out))
2.5 % 97.5 %
(Intercept) 0.04819 1.160e+04
Age 0.87638 9.785e-01
EKGETC 1.24516 3.118e+02
EKGPEA 0.13126 2.961e+02
GCS 1.12548 1.654e+00
K 0.17795 1.599e+00
HCO3 0.90259 1.205e+00
BUN 0.87596 1.015e+00
Cr 0.04814 1.546e+00
out2=glm(Survive~Age+GCS,family=binomial,data=data1)
summary(out2)
Call:
glm(formula = Survive ~ Age + GCS, family = binomial, data = data1)
Deviance Residuals:
Min 1Q Median 3Q Max
-1.695 -0.685 -0.435 0.772 1.962
Coefficients:
Estimate Std. Error z value Pr(>|z|)
(Intercept) 0.0160 1.1395 0.01 0.9888
Age -0.0454 0.0179 -2.54 0.0111 *
GCS 0.2071 0.0642 3.23 0.0012 **
---
Signif. codes: 0 '***' 0.001 '**' 0.01 '*' 0.05 '.' 0.1 ' ' 1
(Dispersion parameter for binomial family taken to be 1)
Null deviance: 92.461 on 74 degrees of freedom
Residual deviance: 72.907 on 72 degrees of freedom
AIC: 78.91
Number of Fisher Scoring iterations: 4
exp(coef(out2))
(Intercept) Age GCS
1.0161 0.9556 1.2301
confint(out2)
2.5 % 97.5 %
(Intercept) -2.21905 2.3195
Age -0.08318 -0.0121
GCS 0.08737 0.3418
exp(confint(out2))
2.5 % 97.5 %
(Intercept) 0.1087 10.171
Age 0.9202 0.988
GCS 1.0913 1.408
m<-lm(Survive~K,data=data1)
m
Call:
lm(formula = Survive ~ K, data = data1)
Coefficients:
(Intercept) K
0.754 -0.106
plot(m)
