Follow-up analyses for RPubs - Extracellular vesicle concentration by diabetes.

Adding BMI to the analysis: there is a significant 3-way interaction between age, diabetes status, and BMI (model 3):

Analysis of variance for model  3 
Analysis of Variance Table of type III  with  Kenward-Roger 
approximation for degrees of freedom
                            Sum Sq     Mean Sq NumDF     DenDF   F.value    Pr(>F)
cenBMI                 61334706421 61334706421     1 104.71194 7.4800045 0.0073282
Age0                    3733801731  3733801731     1 105.96027 0.4553516 0.5012742
dxDiabetes              2590471519  1295235759     2 105.67592 0.1579590 0.8540860
cenBMI:Age0            30819330289 30819330289     1 105.01385 3.7585365 0.0552227
cenBMI:dxDiabetes      85277757728 42638878864     2 104.89494 5.1999761 0.0070265
Age0:dxDiabetes         1658721747   829360873     2 105.64715 0.1011438 0.9038905
cenBMI:Age0:dxDiabetes 63551804258 31775902129     2 105.04015 3.8751941 0.0237804

This plot shows that the interaction is based on differences associated with the pre-diabetics.

2016-12-21: /prj/hnd/git/dataMgr/Projects/MKElab/2015-02-extracellularVesicles/R/2016-12-21-exomeConcAddData.Rmd