- What is reproducible research?
- Why do we care?
- Why reproducibility questions arise?
- The cost of reproducibility
- Reproducibility and statistics
- Current status of reproducibility
- What can we do?
Science is the systematic enterprise of gathering knowledge about the universe and organizing and condensing that knowledge into testable laws and theories
The success and credibility of science are anchored in the willingness of scientists to expose their ideas and results to independent testing and replication by other scientists.
Reproducible research is the ultimate standard for strengthening scientific evidence by independent:
Two pages from Galilei's Sidereus Nuncius (“The Starry Messenger” or “The Herald of the Stars”), Venice, 1610. http://journals.plos.org/ploscompbiol/article?id=info:doi/10.1371/journal.pcbi.1003542
High-throughput biology generates volumes of data
Data-generating technologies are increasingly used to make clinical recommendations and treatment decisions
A problem may be overlooked .. Published .. Get in clinical trials