Zero conditional mean assumption (MLR.4): \(E(u|x_1,x_2,...,x_k) = 0\)
Alternative assumption(MLR.4'): \(E(u) = 0\) and \(cov(x_j,u) = 0\) for \(j=1,2,...,k\).
That is, zero mean and zero correlation
The first implies the second, but is more general (and harder to check).