First things first - get a SQL Server driver
Secondly - install the RODBC package for R and activate it
install.packages("RODBC",repos="http://cran.ma.imperial.ac.uk/")
## Installing package into 'C:/Users/OzandSteph/Documents/R/win-library/3.1'
## (as 'lib' is unspecified)
## package 'RODBC' successfully unpacked and MD5 sums checked
##
## The downloaded binary packages are in
## C:\Users\OzandSteph\AppData\Local\Temp\Rtmp8OgVHl\downloaded_packages
# Activate the ODBC package for use
library("RODBC")