Boxplots: A1 versus A2
Summary Statistics
| Group | Variable | N | Mean | SD | Minimum | Q1 | Median | Q3 | IQR | Maximum |
|---|---|---|---|---|---|---|---|---|---|---|
| A1 | CysCeGFR | 60 | 77.57 | 28.04 | 17.65 | 63.44 | 77.20 | 98.40 | 34.95 | 125.18 |
| A1 | Difference | 60 | 9.32 | 4.23 | 3.04 | 6.48 | 7.91 | 10.51 | 4.03 | 19.37 |
| A1 | ScreGFR | 60 | 68.24 | 27.95 | 7.18 | 53.37 | 68.34 | 89.36 | 35.99 | 117.24 |
| A2 | CysCeGFR | 14 | 92.05 | 24.06 | 46.73 | 76.41 | 95.18 | 110.02 | 33.62 | 123.90 |
| A2 | Difference | 14 | 28.97 | 8.32 | 21.79 | 22.93 | 25.06 | 33.69 | 10.77 | 47.64 |
| A2 | ScreGFR | 14 | 63.08 | 19.57 | 23.81 | 51.23 | 69.14 | 75.52 | 24.29 | 97.58 |
Comparison of Characteristics
| Characteristic |
Group
|
p-value2 | |
|---|---|---|---|
| A1 N = 601 |
A2 N = 141 |
||
| Gender | 0.334 | ||
| Female | 7 (11.7%) | 0 (0.0%) | |
| Male | 53 (88.3%) | 14 (100.0%) | |
| Missing / unrecognized | 0 | 0 | |
| Smoking | 0.576 | ||
| Never | 30 (50.0%) | 9 (64.3%) | |
| Former | 23 (38.3%) | 3 (21.4%) | |
| Current | 7 (11.7%) | 2 (14.3%) | |
| Missing / unrecognized | 0 | 0 | |
| BMI, mean (SD) | 35.0 (7.7) | 31.6 (5.1) | 0.055 |
| Missing / unrecognized | 0 | 0 | |
| Steroid | >0.999 | ||
| No | 60 (100.0%) | 14 (100.0%) | |
| Yes | 0 (0.0%) | 0 (0.0%) | |
| Missing / unrecognized | 0 | 0 | |
| Rheum Diseases | >0.999 | ||
| No | 3 (75.0%) | 0 (NA%) | |
| Yes | 1 (25.0%) | 0 (NA%) | |
| Missing / unrecognized | 56 | 14 | |
| Thyroid Disease | 0.482 | ||
| No | 52 (96.3%) | 12 (92.3%) | |
| Yes | 2 (3.7%) | 1 (7.7%) | |
| Missing / unrecognized | 6 | 1 | |
| Malignancy | >0.999 | ||
| No | 46 (85.2%) | 11 (84.6%) | |
| Yes | 8 (14.8%) | 2 (15.4%) | |
| Missing / unrecognized | 6 | 1 | |
| Liver Disease | >0.999 | ||
| No | 59 (98.3%) | 14 (100.0%) | |
| Yes | 1 (1.7%) | 0 (0.0%) | |
| Missing / unrecognized | 0 | 0 | |
| HIV | >0.999 | ||
| No | 60 (100.0%) | 14 (100.0%) | |
| Yes | 0 (0.0%) | 0 (0.0%) | |
| Missing / unrecognized | 0 | 0 | |
| Hyperlipidemia | >0.999 | ||
| No | 20 (33.3%) | 4 (28.6%) | |
| Yes | 40 (66.7%) | 10 (71.4%) | |
| Missing / unrecognized | 0 | 0 | |
| Hypertension | 0.506 | ||
| No | 15 (25.0%) | 5 (35.7%) | |
| Yes | 45 (75.0%) | 9 (64.3%) | |
| Missing / unrecognized | 0 | 0 | |
| DM2 | 0.856 | ||
| No | 37 (61.7%) | 9 (64.3%) | |
| Yes | 23 (38.3%) | 5 (35.7%) | |
| Missing / unrecognized | 0 | 0 | |
| 1 n (%); Mean (SD) | |||
| 2 Fisher’s exact test; Welch Two Sample t-test; Pearson’s Chi-squared test | |||
Logistic Regression
| Predictor | Adjusted OR | 95% CI | p-value |
|---|---|---|---|
| genderMale | 0.000 | 0.000 to Inf | 0.994 |
| SmokingFormer | 7.589 | 0.963 to 59.812 | 0.054 |
| SmokingCurrent | 1.171 | 0.127 to 10.772 | 0.889 |
| BMI | 1.162 | 1.008 to 1.338 | 0.038 |
| Thyroid DiseaseYes | 0.108 | 0.004 to 2.749 | 0.178 |
| MalignancyYes | 1.538 | 0.190 to 12.443 | 0.686 |
| Liver DiseaseYes | 1196728.020 | 0.000 to Inf | 0.998 |
| HyperlipidemiaYes | 0.956 | 0.162 to 5.638 | 0.960 |
| HypertensionYes | 1.727 | 0.288 to 10.362 | 0.550 |
| DM2Yes | 0.632 | 0.122 to 3.283 | 0.585 |
Model N = 67 (A1: 54; A2: 13). Excluded for missing predictors: 7.
Predictors omitted for no variation: Steroid, HIV.
Table notes: Only Group A (CysCeGFR > ScreGFR) is included. Difference = CysCeGFR − ScreGFR, in absolute eGFR units, not percent. A1: 0 < Difference < 20; A2: Difference > 20. Exactly 20 is excluded (0 selected records). Each patient’s latest valid paired laboratory record is selected before restricting to Group A; its date is the later of the two laboratory timestamps. Categorical percentages use nonmissing subgroup denominators. BMI is mean (SD). Comparison p-values use Welch’s t-test for BMI and chi-square or Fisher’s exact tests for categorical characteristics. Logistic outcome: A1 = 1, A2 = 0. Rheum Diseases is excluded from regression and its complete-case check but retained in the comparison table. All other 11 characteristics, including HIV, are candidate predictors. The model uses complete cases for those predictors and omits predictors with no variation in that sample. Reference levels are Female, Never smoking, and No where present. Adjusted odds ratios compare the odds of A1 versus A2; confidence intervals are Wald 95% intervals. Missing/unknown values remain missing. P-values are unadjusted.