Problem 1: ACRN3 Alleles

A sample of 436 people was classified according to weather they had the R or X allele. The were 244 people with the R allele and 192 with the X allele. I am going to determine whether the two alleles are equally likely.

Hypotheses:

Null hypothesis: The R and X alleles are equally likely.

Alternative hypothesis: The R and X alleles are not equally likely.

Entering Observed Data:

ACTN3 <- c(R = 244, X = 192)
ACTN3
##   R   X 
## 244 192

Chi-Square Goodness of Fit Test:

ACTN3_test <- chisq.test( ACTN3, p = c(0.50, 0.50) )
ACTN3_test
## 
##  Chi-squared test for given probabilities
## 
## data:  ACTN3
## X-squared = 6.2018, df = 1, p-value = 0.01276

Conclusion:

P-value = 0.01276

I am using a significance level of alpha = 0.05 this is grader than the p-value so we reject the null hypothesis. There is sufficient evidence that the R and A alleles are not equally likely. The sample contained more R alleles than X alleles.

Problem 2: Vitamin Use and Gender

The Nutrition Study dataset contains information about vitamin use and the sex of the participants. OI will perform a chi-square test of association to determine whether vitamin use is associated with sex.

Reading Data Set:

NutritionStudy <- read.csv("NutritionStudy.csv")
head(NutritionStudy)
##   ID Age Smoke Quetelet Vitamin Calories  Fat Fiber Alcohol Cholesterol
## 1  1  64    No  21.4838       1   1298.8 57.0   6.3     0.0       170.3
## 2  2  76    No  23.8763       1   1032.5 50.1  15.8     0.0        75.8
## 3  3  38    No  20.0108       2   2372.3 83.6  19.1    14.1       257.9
## 4  4  40    No  25.1406       3   2449.5 97.5  26.5     0.5       332.6
## 5  5  72    No  20.9850       1   1952.1 82.6  16.2     0.0       170.8
## 6  6  40    No  27.5214       3   1366.9 56.0   9.6     1.3       154.6
##   BetaDiet RetinolDiet BetaPlasma RetinolPlasma    Sex VitaminUse PriorSmoke
## 1     1945         890        200           915 Female    Regular          2
## 2     2653         451        124           727 Female    Regular          1
## 3     6321         660        328           721 Female Occasional          2
## 4     1061         864        153           615 Female         No          2
## 5     2863        1209         92           799 Female    Regular          1
## 6     1729        1439        148           654 Female         No          2

Hypothesis:

Null Hypothesis: There is no association between sex and vitamin use. The two variables are independent.

Alternative Hypothesis: There is an association between sex and vitamin use. The two variables are not independent.

Contingency Table:

vitamin_table <- table( NutritionStudy$Sex, NutritionStudy$VitaminUse )
vitamin_table
##         
##           No Occasional Regular
##   Female  87         77     109
##   Male    24          5      13

Chi-Square Test of Association:

vitamin_test <- chisq.test(vitamin_table)
vitamin_test
## 
##  Pearson's Chi-squared test
## 
## data:  vitamin_table
## X-squared = 11.071, df = 2, p-value = 0.003944

Conclusion:

The P-value = 0.003944

I am using a significance level of 0.05; in this case, 0.05 is greater than the p-value we go so we will reject the null hypothesis. There is sufficient evidence that there is a significant association between sex and vitamin use. This sample showed that females use vitamins more regularly than men. Vitamin use and sex are not independent in the sample.

Problem 3: Fish Gill Rate Calcium Level

I will use a one-way ANOVA test to determine whether the mean gill rate differs depending on the calcium level of the water.

Importing Data Set

FishGills3 <- read.csv("FishGills3.csv")
head(FishGills3)
##   Calcium GillRate
## 1     Low       55
## 2     Low       63
## 3     Low       78
## 4     Low       85
## 5     Low       65
## 6     Low       98

Hypothesis:

Null Hypothesis: The mean gill rate is the same for all three calcium levels.

Alternative Hypothesis: At least one mean gill rate is different.

ANOVA Test:

gill_anova <- aov(GillRate ~ Calcium, data = FishGills3)
summary(gill_anova)
##             Df Sum Sq Mean Sq F value Pr(>F)  
## Calcium      2   2037  1018.6   4.648 0.0121 *
## Residuals   87  19064   219.1                 
## ---
## Signif. codes:  0 '***' 0.001 '**' 0.01 '*' 0.05 '.' 0.1 ' ' 1

Conclusion:

P-vales = 0.0121

Since the p-value of 0.0121 is less than 0.05, we reject the null hypothesis. There is sufficient evidence to conclude that the mean gill rate differs depending on the calcium level of the water.