Operative & Pathway Variables Stapled LAR
N = 475
1
Hand-sewn ISR
N = 146
1
p-value2
Operative Time (min) 211 (167, 258) 259 (224, 288) <0.001
Blood Loss (mL) 262 (154, 373) 231 (167, 288) 0.002
Length of Stay (days) 6 (5, 7) 8 (7, 9) <0.001
Anastomotic Leak Grade

0.020
    No Leak 430 (91%) 129 (88%)
    Grade A 7 (1.5%) 9 (6.2%)
    Grade B 14 (2.9%) 4 (2.7%)
    Grade C 24 (5.1%) 4 (2.7%)
Late Complication 63 (13%) 16 (11%) 0.5
Any Anastomotic Failure Pathway 87 (18%) 22 (15%) 0.4
Local Recurrence 30 (6.3%) 8 (5.5%) 0.7
1 Median (Q1, Q3); n (%)
2 Wilcoxon rank sum test; Fisher’s exact test; Pearson’s Chi-squared test