Variable Stapled LAR
N = 475
1
Hand-sewn ISR
N = 146
1
p-value2
Age 59 (12) 60 (11) 0.2
Sex

0.011
    Male 230 (48%) 89 (61%)
    Female 245 (52%) 57 (39%)
BMI 26.7 (4.7) 25.3 (3.6) <0.001
ASA Class

0.3
    ASA I-II 365 (77%) 106 (73%)
    ASA III-IV 110 (23%) 40 (27%)
Smoking 101 (21%) 28 (19%) 0.7
Diabetes 250 (53%) 21 (14%) <0.001
Cardiovascular Disease 76 (16%) 15 (10%) 0.11
Previous Abdominal Surgery 169 (36%) 22 (15%) <0.001
Preop Hemoglobin 12.96 (1.16) 13.33 (1.00) <0.001
Creatinine 0.88 (0.18) 0.91 (0.17) 0.038
Preop Albumin 4.10 (0.45) 4.15 (0.26) 0.15
Tumor Distance from Anal Verge (cm) 6.83 (2.57) 2.13 (0.74) <0.001
T Stage

0.002
    T1-T2 245 (52%) 53 (36%)
    T3-T4 230 (48%) 93 (64%)
N Stage

<0.001
    Negative 156 (33%) 79 (54%)
    Positive 319 (67%) 67 (46%)
neoadjuvant_therapy

<0.001
    None 54 (11%) 0 (0%)
    Chemotherapy 30 (6.3%) 42 (29%)
    Chemoradiotherapy 391 (82%) 104 (71%)
1 Mean (SD); n (%)
2 Welch Two Sample t-test; Pearson’s Chi-squared test