Executive Summary
Despite a national mandate to improve outcomes, maternal mortality in
the UK has not only failed to decline but has increased over the last
decade. The data for the 2022–24 triennium reveals persistent systemic
challenges, shifting clinical aetiologies, and entrenched socio-economic
and ethnic inequalities.
Overall Trends and Baseline Targets
This investigation, led by Oxford Population Health’s National
Perinatal Epidemiology Unit (NPEU), tracks data on all UK women who died
during pregnancy or within six weeks postpartum. Published as an advance
data brief ahead of the full Saving Lives, Improving Mothers’
Care confidential enquiry report, the data paints a deeply
concerning picture.
In the 2022–24 period, 252 women died from direct or
indirect causes among 1,969,321 recorded maternities,
yielding an overall maternal death rate of 12.80 per 100,000
maternities. This rate is 20% higher than the
2009–11 baseline, representing a significant divergence from the
government’s stated ambition to halve the rate of maternal mortality in
England (Figure A). As Professor Marian Knight,
MBRRACE-UK programme lead, notes: “A 20% increase in maternal deaths
over a 15-year period is very concerning, especially as pressures on
maternity services have not eased.”
Crucially, the exclusion of maternal deaths directly attributable to
COVID-19 has minimal impact on the overall narrative. The number of
deaths due to COVID-19 dropped significantly, with only six women dying
from related complications in 2022–24. When these anomalous deaths are
excluded, rates of overall and indirect maternal deaths remained
statistically significantly elevated compared to the corresponding rates
in 2019–21 (Figure G). This underscores the critical
need for renewed structural efforts to tackle underlying maternal
mortality beyond pandemic-centric explanations.
Primary Clinical Aetiologies
The clinical drivers of maternal mortality remain concentrated in a
few key areas during pregnancy and up to six weeks postpartum
(Figure B):
- Thrombosis and Thromboembolism: Remains the leading
cause of maternal death.
- Cardiac Disease: Represents the second most common
aetiology.
- Psychiatric Causes: Ranks as the third most common
driver in the immediate perinatal period.
Beyond the traditional six-week postpartum window (six weeks to one
year postpartum), maternal suicides remain the leading
singular cause of maternal death. Collectively, deaths from psychiatric
causes accounted for an alarming 33% of all maternal
deaths during this extended period, highlighting a critical gap in
long-term maternal mental health provision.
Persistent Systemic Inequalities
Maternal mortality in the UK continues to disproportionately impact
specific demographic groups. The data confirms that disparities across
age, ethnicity, and socio-economic status are highly persistent
(Figure F).
- Age: Compared to women aged 25–29, women aged 35 or
older were nearly twice as likely to die.
- Ethnicity: Ethnic disparities remain starkly
evident (Figure C). Black women face a nearly
three-fold higher risk of maternal mortality compared
to White women (Figure D). Asian women also demonstrate
a slightly elevated risk of maternal death compared to the White
reference group.
- Deprivation: Socio-economic status heavily dictates
maternal outcomes. Women living in the most deprived areas (IMD Quintile
5) continue to experience a maternal mortality rate twice as
high as those residing in the least deprived areas
(Figure E).
Epidemiological Context: Intersectionality and Clinical
Disparities
The persistence of the disparities visualised above strikes at the
heart of current epidemiological research into maternal mortality.
Addressing these gaps requires examining the concepts of
intersectionality (how overlapping identities affect risk) and
unmeasured confounding variables in clinical outcomes. Based on
MBRRACE-UK enquiries and Office for National Statistics data, two
critical issues emerge:
1. The Intersectional Data Gap: Ethnicity, Deprivation, and
Geography
The Problem of Small Numbers and Deductive
Disclosure Maternal death in the UK is a statistically rare
event (approximately 250–300 deaths over a three-year period). If
researchers divide this cohort into intersectional subsets, for example,
“Black women, living in the most deprived quintile, in the West
Midlands”. The resulting number of deaths in that specific demographic
cell may be zero, one, or two. Because maternal deaths are investigated
confidentially, publishing data at this level of granularity risks
deductive disclosure (inadvertently identifying deceased individuals),
heavily restricting how data can be publicly reported.
Deprivation Does Not Fully Explain Ethnic Risk
Despite these reporting limitations, researchers have conducted
multivariate analyses to determine if ethnic disparities are merely a
proxy for socio-economic poverty. The findings are unequivocal:
deprivation does not fully explain the ethnic gap. Even when controlling
for socio-economic status and area of residence, Black and Asian women
still face a significantly higher baseline risk of mortality than White
women in equivalent income brackets.
Conclusion
The data for 2022–24 clearly defines the current frontier of maternal
medicine. Traditional metrics, which track deaths by isolated
demographic categories, are no longer sufficient to drive the necessary
clinical improvements. To resolve the stark disparities visualised in
this report, the UK healthcare system must transition towards highly
individualised, intersectional risk assessments that account for
specific genetic predispositions, nuanced socio-economic realities, and
the systemic biases embedded within current diagnostic pathways.
National Policy Response: The Maternal Care Bundle
In direct response to the escalating mortality rates and persistent
inequalities outlined in the triennial data, NHS England introduced the
‘Maternal Care Bundle’ (MCB) in 2026. This national policy mandates that
all NHS trusts providing maternity services, along with Integrated Care
Boards (ICBs), fully implement a targeted suite of interventions by
March 2027.
The MCB is designed to establish a baseline of best practice across
five critical clinical areas that directly map onto the leading causes
of maternal mortality and morbidity identified in the data. Crucially,
the interventions are designed with ‘proportionate universalism’ to
actively reduce the stark health inequalities experienced by minority
ethnic women and those from the most deprived areas.
The five mandated clinical elements are as follows:
1. Venous Thromboembolism (VTE)
To combat the leading direct cause of maternal death, the MCB
requires screening for VTE risk at the earliest possible opportunity.
Specifically at the first NHS care contact with a positive pregnancy
test, even prior to formal antenatal booking.
- Women are to be offered a national self-assessment
questionnaire.
- Those identified as high risk must be offered low molecular weight
heparin (LMWH) and receive it within 72 hours.
2. Pre-Hospital and Acute Care
Recognising that unwell pregnant women often present across various
emergency and community settings, this element focuses on the timely
detection and management of maternal deterioration.
- Trusts must implement the national Maternity Early Warning Score
(MEWS) tool across all settings for women who are pregnant or have been
pregnant in the past four weeks.
- Ambulance services and labour wards must implement a standardised
pre-alert communication system and ensure adequate signage to facilitate
the rapid conveyance of obstetric emergencies.
3. Epilepsy in Pregnancy
With neurological conditions representing a leading indirect cause of
death, the NHS now mandates rapid optimisation of epilepsy care.
- Every pregnant woman with epilepsy must have access to a local
epilepsy in pregnancy team, consisting at minimum of an epilepsy nurse
specialist or neurologist, and a maternal medicine obstetrician.
- Complex cases must be seamlessly referred to a Maternal Medicine
Network (MMN) multidisciplinary team.
4. Maternal Mental Health
Addressing the reality that suicide remains the leading cause of
death between six weeks and one year postpartum, this element
standardises emotional wellbeing assessments.
- Women must be invited to self-administer the Whooley questions ahead
of specific antenatal and postnatal appointments.
- Positive screens must trigger further assessment using the Edinburgh
Postnatal Depression Scale (EPDS).
- Clinicians are required to facilitate compassionate conversations
and timely referrals to specialist perinatal mental health services
where clinical concern exists.
5. Obstetric Haemorrhage
To reduce severe morbidity and mortality from significant bleeding,
the MCB standardises identification and escalation protocols.
- Visual estimation of blood loss is to be replaced by cumulative
measured blood loss for all births, utilising scales and under-buttock
collection drapes.
- Clinical escalation is rigidly defined by cumulative volume
thresholds (alerting the multidisciplinary team at 500mL, treating as an
obstetric emergency with senior presence at 1,000mL, and requiring
consultant attendance at 1,500mL).
- Multidisciplinary team case reviews are mandated for all significant
bleeds exceeding two litres.
Conclusion
The NHS Maternal Care Bundle represents a vital systemic shift. By
standardising the clinical response to thrombosis, haemorrhage,
neurological risks, and psychiatric vulnerabilities, and by embedding
early warning scores across the entire acute care footprint, the policy
provides a direct, actionable framework to begin reversing the alarming
mortality trends and entrenched demographic disparities visualised in
this review.
Patient Empowerment and Self-Advocacy
While reversing maternal mortality trends relies heavily on systemic
healthcare reforms, the tragic realities behind the statistics highlight
the vital role of patient empowerment. Women must be supported not
merely as passive recipients of care, but as educated, active partners
in their own health journeys.
The NHS Maternal Care Bundle explicitly states that care must be
tailored around the informed decision of each service user. To achieve
this, pregnant women and their families must be equipped to recognise
clinical red flags and feel empowered to ask direct, challenging
questions of their healthcare providers.
1. Recognising the Red Flags of Venous Thromboembolism (VTE)
Blood clots remain the leading direct cause of maternal death.
Pregnancy naturally increases clotting risks, but certain complications
drastically multiply this danger.
Hyperemesis Gravidarum (HG): Extreme pregnancy
sickness is not simply ‘morning sickness’. The NHS classifies HG that
causes dehydration or immobility as a primary, high-risk factor for
developing a VTE. Dehydration thickens the blood, whilst immobility
allows it to pool, creating a highly dangerous environment for clot
formation.
Asymmetrical Leg Swelling: While general,
symmetrical swelling in the legs and ankles is a normal physiological
symptom of late pregnancy, a noticeable difference in size between the
two legs is a critical warning sign. Recent clinical research confirms
that asymmetric lower limb oedema (where one calf measures significantly
larger than the other) is a highly predictive symptom of Deep Vein
Thrombosis (DVT) in the postpartum period. Women should immediately
report uneven swelling, redness, or localised heat in one leg.
Symptoms of a Pulmonary Embolism (PE): If a clot
travels to the lungs, it becomes a life-threatening emergency. Women
should seek immediate emergency care if they experience:
- Sudden shortness of breath or difficulty breathing.
- Unexplained chest pain, often worse when breathing in.
- A sudden, unexplained spike in resting heart rate
(tachycardia).
- Note on Wearable Technology: While consumer smartwatches
cannot diagnose a blood clot, they can alert women to sudden spikes in
resting heart rate or drops in blood oxygen. This objective data can be
a powerful tool to validate a woman’s symptoms when presenting at triage
or an emergency department.
2. Crucial Questions to Ask Healthcare Providers
Patients should be actively encouraged to advocate for their safety.
If a woman is diagnosed with severe pregnancy sickness, or possesses
other risk factors (such as a high BMI or a family history of clots),
she should ask her clinical team:
- “Have I been formally assessed for my VTE risk?”
The NHS mandates that women must be offered a national self-assessment
questionnaire on VTE risk at their very first care contact with a
positive pregnancy test.
- “Given my severe sickness and dehydration, am I at high risk
for blood clots?”
- “Should I be prescribed blood thinners?” National
guidelines dictate that women identified as high risk for VTE must be
offered low molecular weight heparin (LMWH) within 72 hours.
- “Who do I escalate to if my symptoms worsen?”
3. Advocating for Mental Health
With psychiatric causes accounting for a third of maternal deaths
between six weeks and one year postpartum, mental health requires the
same level of rigorous advocacy as physical health.
- Demand Routine Screening: Women should expect to be
asked the ‘Whooley questions’ (screening for low mood and loss of
interest) at routine antenatal and postnatal appointments.
- Requesting Further Support: If a woman feels her
mental health is deteriorating, she can advocate for a formal assessment
using the Edinburgh Postnatal Depression Scale (EPDS) and request a
direct referral to specialist perinatal mental health services.
Conclusion: A Shared Responsibility
No amount of personal vigilance can replace a timely, accurate
medical diagnosis. However, by equipping women with the knowledge of
clinical red flags and the confidence to question their care plans, we
can build a critical safety net. Healthcare providers have a duty to
ensure women are supported to understand their options and the potential
risks, fostering an environment where a patient stating, “I am worried
about my risk of a blood clot,” is met with immediate clinical
validation rather than dismissal.