Fully combined Cox model
Stage- and age-group-stratified model with affordability and accessibility separated
Characteristic	HR (95% CI)	p-value
Immune class: B_Quiet vs B_Adaptive	1.66 (1.25, 2.2)	<0.001
Immune class: B_Innate vs B_Adaptive	1.75 (1.3, 2.36)	<0.001
Neighborhood advantage: low vs high	1.13 (0.76, 1.67)	0.552
Neighborhood disadvantage: high vs low	1.07 (0.75, 1.5)	0.718
Affordability: low vs high	0.89 (0.65, 1.22)	0.474
Accessibility: low vs high	1.26 (0.98, 1.62)	0.071
Model includes immune class, neighborhood advantage, neighborhood disadvantage, healthcare affordability, and healthcare accessibility. Baseline hazards were stratified by stage and age group.