library(readxl)
library(readr)
library(tableone)
library(knitr)
library(kableExtra)
library(dplyr)
##
## Adjuntando el paquete: 'dplyr'
## The following object is masked from 'package:kableExtra':
##
## group_rows
## The following objects are masked from 'package:stats':
##
## filter, lag
## The following objects are masked from 'package:base':
##
## intersect, setdiff, setequal, union
library(tibble)
library(survival)
library(ggplot2)
library(broom)
library(mice)
##
## Adjuntando el paquete: 'mice'
## The following object is masked from 'package:stats':
##
## filter
## The following objects are masked from 'package:base':
##
## cbind, rbind
Base de datos
Basecom = read_excel("C:\\Users\\gio73\\Documents\\Tesis\\Data\\tesis\\Base de mahalanobis\\Sin pacientes con datos erroneos\\base_completa1.xlsx")
Baseline_original = read_excel("C:\\Users\\gio73\\Documents\\Tesis\\Data\\tesis\\YLab_T2DM_Clinical Baseline Information.xlsx")
Metabolomics_original = read_excel("C:\\Users\\gio73\\Documents\\Tesis\\Data\\tesis\\Base de mahalanobis\\Metabolomics_2.xlsx")
Baseline_sin_errores = read_excel("C:\\Users\\gio73\\Documents\\Tesis\\Data\\tesis\\Base de mahalanobis\\Baseline_sin_errores.xlsx")
Outliers
Baseline
# Diccionario de nombres
diccionario = c(
Gender = "Sexo",
Group = "Grupo",
Age = "Edad",
Height = "Altura",
Weight = "Peso",
BMI = "Índice de masa corporal (kg/m²)",
`Waistline (cm)` = "Circunferencia de cintura (cm)",
`SBP (mmHg)` = "Presión sistólica (mm Hg)",
`DBP (mmHg)` = "Presión diastólica (mm Hg)",
`HBA (%)` = "Hemoglobina A1c (%)",
`FBG (mM)` = "Glucosa en ayunas (mM)",
`ALT (U/L)` = "Alanina aminotransferasa (U/L)",
`AST (U/L)` = "Aspartato aminotransferasa (U/L)",
`Urea (mM)` = "Urea (mM)",
`Cre (uM)` = "Creatinina (µM)",
`UA (uM)` = "Ácido úrico (µM)",
`ALB (g/L)` = "Albúmina (g/L)",
`TC (mM)` = "Colesterol total (mM)",
`TG (mM)` = "Triglicéridos (mM)",
`HDL-C (mM)` = "Colesterol HDL (mM)",
`LDL-C (mM)` = "Colesterol LDL (mM)",
`ALP (U/L)` = "Fosfatasa alcalina (U/L)",
#`Υ-GT (U/L)` = "Gamma-GT (U/L)",
`T-BIL (uM)` = "Bilirrubina total (µM)",
`D-BIL (uM)` = "Bilirrubina directa (µM)",
`TBA (uM)` = "Ácidos biliares totales (µM)",
`CHE (U/L)` = "Colinesterasa (U/L)",
`WBC (10^9/L)` = "Leucocitos (10^9/L)",
`NEUT (%)` = "Neutrófilos (%)",
`LYMPH (%)` = "Linfocitos (%)",
`EO (%)` = "Eosinófilos (%)",
`BASO (%)` = "Basófilos (%)"
)
# Renombrar variables usando el diccionario
nombres_originales = names(Baseline_original)
nombres_nuevos = sapply(nombres_originales, function(nombre) {
if (nombre %in% names(diccionario)) {
diccionario[[nombre]]
} else {
nombre # conservar si no está en el diccionario
}
})
names(Baseline_original) = nombres_nuevos
# variables continuas y categóricas
vars_continuas <- c("Edad", "Altura", "Peso", "Índice de masa corporal (kg/m²)",
"Circunferencia de cintura (cm)", "Presión sistólica (mm Hg)",
"Presión diastólica (mm Hg)", "Glucosa en ayunas (mM)",
"Colesterol total (mM)", "Triglicéridos (mM)",
"Colesterol HDL (mM)", "Colesterol LDL (mM)",
"Alanina aminotransferasa (U/L)", "Aspartato aminotransferasa (U/L)",
"Urea (mM)", "Creatinina (µM)", "Ácido úrico (µM)", "Albúmina (g/L)",
"Fosfatasa alcalina (U/L)", "Bilirrubina total (µM)",
"Bilirrubina directa (µM)", "Ácidos biliares totales (µM)",
"Colinesterasa (U/L)", "Leucocitos (10^9/L)", "Υ-GT (U/L)")
vars_categoricas <- c("Sexo")
vars_edad <- "Edad categorizada"
vars_porcentuales <- c("Neutrófilos (%)","Linfocitos (%)","Eosinófilos (%)","Basófilos (%)", "Hemoglobina A1c (%)")
vars_explorar <- c(vars_continuas, vars_porcentuales)
# Recorrer cada variable continua
for (var in vars_explorar) {
# Asegurarse de que los datos sean numéricos y sin NA
b <- suppressWarnings(as.numeric(Baseline_original[[var]]))
b <- na.omit(b)
if (length(b) > 0) {
cat("\n=============================\n")
cat("Variable:", var, "\n")
cat("-----------------------------\n")
# 5 valores más bajos
cat("5 valores más bajos:\n")
print(head(sort(b), 5))
# 5 valores más altos
cat("5 valores más altos:\n")
print(tail(sort(b), 5))
cat("=============================\n")
} else {
cat("\nVariable:", var, "no tiene datos numéricos válidos.\n")
}
}
##
## =============================
## Variable: Edad
## -----------------------------
## 5 valores más bajos:
## [1] 20 25 26 27 27
## 5 valores más altos:
## [1] 69 69 72 72 74
## =============================
##
## =============================
## Variable: Altura
## -----------------------------
## 5 valores más bajos:
## [1] 145 147 153 153 153
## 5 valores más altos:
## [1] 188.0 189.0 190.0 192.0 196.5
## =============================
##
## =============================
## Variable: Peso
## -----------------------------
## 5 valores más bajos:
## [1] 41.1 43.5 44.0 44.3 44.6
## 5 valores más altos:
## [1] 109.3 111.7 112.2 113.4 128.9
## =============================
##
## =============================
## Variable: Índice de masa corporal (kg/m²)
## -----------------------------
## 5 valores más bajos:
## [1] 15.50457 16.34429 16.67410 17.04986 17.09975
## 5 valores más altos:
## [1] 36.22159 36.29226 39.78999 39.95244 40.33929
## =============================
##
## =============================
## Variable: Circunferencia de cintura (cm)
## -----------------------------
## 5 valores más bajos:
## [1] 59 59 59 59 60
## 5 valores más altos:
## [1] 109 110 111 117 123
## =============================
##
## =============================
## Variable: Presión sistólica (mm Hg)
## -----------------------------
## 5 valores más bajos:
## [1] 84 90 92 95 95
## 5 valores más altos:
## [1] 172 174 176 179 208
## =============================
##
## =============================
## Variable: Presión diastólica (mm Hg)
## -----------------------------
## 5 valores más bajos:
## [1] 45 51 53 54 55
## 5 valores más altos:
## [1] 108 109 110 115 125
## =============================
##
## =============================
## Variable: Glucosa en ayunas (mM)
## -----------------------------
## 5 valores más bajos:
## [1] 3.91 4.15 4.24 4.26 4.27
## 5 valores más altos:
## [1] 17.29 18.22 18.56 21.15 30.00
## =============================
##
## =============================
## Variable: Colesterol total (mM)
## -----------------------------
## 5 valores más bajos:
## [1] 2.20 2.75 3.04 3.05 3.23
## 5 valores más altos:
## [1] 8.02 8.05 8.19 8.72 29.10
## =============================
##
## =============================
## Variable: Triglicéridos (mM)
## -----------------------------
## 5 valores más bajos:
## [1] 0.38 0.40 0.42 0.45 0.49
## 5 valores más altos:
## [1] 6.69 7.82 10.79 11.34 13.14
## =============================
##
## =============================
## Variable: Colesterol HDL (mM)
## -----------------------------
## 5 valores más bajos:
## [1] 0.66 0.67 0.76 0.81 0.82
## 5 valores más altos:
## [1] 2.21 2.23 2.24 2.33 2.40
## =============================
##
## =============================
## Variable: Colesterol LDL (mM)
## -----------------------------
## 5 valores más bajos:
## [1] 1.25 1.35 1.41 1.44 1.45
## 5 valores más altos:
## [1] 4.75 4.90 5.27 5.36 6.09
## =============================
##
## =============================
## Variable: Alanina aminotransferasa (U/L)
## -----------------------------
## 5 valores más bajos:
## [1] 5 6 6 7 7
## 5 valores más altos:
## [1] 104 107 181 302 703
## =============================
##
## =============================
## Variable: Aspartato aminotransferasa (U/L)
## -----------------------------
## 5 valores más bajos:
## [1] 0.85 11.00 11.00 11.00 12.00
## 5 valores más altos:
## [1] 81 90 168 275 292
## =============================
##
## =============================
## Variable: Urea (mM)
## -----------------------------
## 5 valores más bajos:
## [1] 2.43 2.50 2.61 2.65 2.66
## 5 valores más altos:
## [1] 8.72 8.83 8.98 9.38 397.00
## =============================
##
## =============================
## Variable: Creatinina (µM)
## -----------------------------
## 5 valores más bajos:
## [1] 34 34 37 38 39
## 5 valores más altos:
## [1] 102 108 114 125 855
## =============================
##
## =============================
## Variable: Ácido úrico (µM)
## -----------------------------
## 5 valores más bajos:
## [1] 5.07 6.13 45.70 133.00 152.00
## 5 valores más altos:
## [1] 618 636 640 658 677
## =============================
##
## =============================
## Variable: Albúmina (g/L)
## -----------------------------
## 5 valores más bajos:
## [1] 18.4 38.0 38.2 39.5 39.7
## 5 valores más altos:
## [1] 51.7 52.9 68.8 4401.0 4701.0
## =============================
##
## =============================
## Variable: Fosfatasa alcalina (U/L)
## -----------------------------
## 5 valores más bajos:
## [1] 2.05 38.00 40.00 40.00 41.00
## 5 valores más altos:
## [1] 135 139 152 164 186
## =============================
##
## =============================
## Variable: Bilirrubina total (µM)
## -----------------------------
## 5 valores más bajos:
## [1] 5.6 6.8 7.0 7.0 7.2
## 5 valores más altos:
## [1] 34.3 34.7 38.8 47.0 52.0
## =============================
##
## =============================
## Variable: Bilirrubina directa (µM)
## -----------------------------
## 5 valores más bajos:
## [1] 1.1 1.4 1.5 1.6 1.8
## 5 valores más altos:
## [1] 8.3 9.0 9.6 11.9 14.5
## =============================
##
## =============================
## Variable: Ácidos biliares totales (µM)
## -----------------------------
## 5 valores más bajos:
## [1] 0.1 0.4 0.6 0.6 0.6
## 5 valores más altos:
## [1] 9.1 10.8 12.0 12.1 16.6
## =============================
##
## =============================
## Variable: Colinesterasa (U/L)
## -----------------------------
## 5 valores más bajos:
## [1] 144 178 187 209 219
## 5 valores más altos:
## [1] 605 624 629 650 870
## =============================
##
## =============================
## Variable: Leucocitos (10^9/L)
## -----------------------------
## 5 valores más bajos:
## [1] 2.70 2.93 2.98 3.15 3.29
## 5 valores más altos:
## [1] 10.68 11.18 11.23 11.52 628.00
## =============================
##
## =============================
## Variable: Υ-GT (U/L)
## -----------------------------
## 5 valores más bajos:
## [1] 8 8 8 9 10
## 5 valores más altos:
## [1] 140 143 195 261 271
## =============================
##
## =============================
## Variable: Neutrófilos (%)
## -----------------------------
## 5 valores más bajos:
## [1] 33.3 34.9 35.5 37.6 40.2
## 5 valores más altos:
## [1] 73.0 73.4 74.1 74.7 75.0
## =============================
##
## =============================
## Variable: Linfocitos (%)
## -----------------------------
## 5 valores más bajos:
## [1] 16.0 16.1 16.3 16.8 18.6
## 5 valores más altos:
## [1] 54.4 54.6 57.9 60.0 3401.0
## =============================
##
## =============================
## Variable: Eosinófilos (%)
## -----------------------------
## 5 valores más bajos:
## [1] 0.06 0.06 0.07 0.11 0.16
## 5 valores más altos:
## [1] 6.9 7.0 9.4 10.5 11.4
## =============================
##
## =============================
## Variable: Basófilos (%)
## -----------------------------
## 5 valores más bajos:
## [1] 0.00 0.00 0.00 0.01 0.02
## 5 valores más altos:
## [1] 1.5 1.7 1.8 1.8 2.1
## =============================
##
## =============================
## Variable: Hemoglobina A1c (%)
## -----------------------------
## 5 valores más bajos:
## [1] 4.9 5.0 5.0 5.0 5.0
## 5 valores más altos:
## [1] 12.5 13.5 13.6 14.3 14.8
## =============================
# Variables con datos anormales
vars_continuas3 <- c( "Colesterol total (mM)",
"Alanina aminotransferasa (U/L)", "Urea (mM)", "Creatinina (µM)",
"Albúmina (g/L)", "Leucocitos (10^9/L)", "Linfocitos (%)")
# Límites usando media ± 3SD
limites <- lapply(vars_continuas3, function(var) {
# Convertir a numérico
x <- suppressWarnings(
as.numeric(Baseline_original[[var]])
)
# Calcular media y SD
media <- mean(x, na.rm = TRUE)
sdv <- sd(x, na.rm = TRUE)
# Límites
c(
inf = media - 3 * sdv,
sup = media + 3 * sdv
)
})
# Asignar nombres
names(limites) <- vars_continuas3
# Encontrar filas con outliers
outlier_rows <- unique(unlist(
lapply(vars_continuas3, function(var) {
# Convertir a numérico
x <- suppressWarnings(
as.numeric(Baseline_original[[var]])
)
# Buscar índices fuera de límites
which(
x < limites[[var]]["inf"] |
x > limites[[var]]["sup"]
)
})
))
# Extraer filas con outliers
filas_outliers <- Baseline_original[outlier_rows, ]
# Seleccionar columnas numéricas
numeric_cols <- names(Baseline_original)[
sapply(Baseline_original, is.numeric)
]
# Calcular promedios
promedios <- sapply(
Baseline_original[numeric_cols],
function(x) mean(x, na.rm = TRUE)
)
# Comparar outliers vs promedio
comparaciones <- lapply(
1:nrow(filas_outliers),
function(i) {
fila <- filas_outliers[i, numeric_cols]
data.frame(
Fila = outlier_rows[i],
Variable = numeric_cols,
Valor = as.numeric(fila),
Promedio = promedios[numeric_cols],
Diferencia = as.numeric(fila) - promedios[numeric_cols],
row.names = NULL
)
}
)
# Unir resultados
comparaciones_df <- do.call(rbind, comparaciones)
# Mostrar tabla final
print(comparaciones_df)
## Fila Variable Valor Promedio Diferencia
## 1 138 Grupo 2.00000 1.6666667 3.333333e-01
## 2 138 Edad 29.00000 48.1033333 -1.910333e+01
## 3 138 Altura 160.50000 168.9810000 -8.481000e+00
## 4 138 Peso 64.90000 72.0360000 -7.136000e+00
## 5 138 Índice de masa corporal (kg/m²) 25.19385 25.1264947 6.736020e-02
## 6 138 Circunferencia de cintura (cm) 77.00000 84.4100000 -7.410000e+00
## 7 138 Presión sistólica (mm Hg) 125.00000 126.9833333 -1.983333e+00
## 8 138 Presión diastólica (mm Hg) 77.00000 78.7066667 -1.706667e+00
## 9 138 Hemoglobina A1c (%) 5.30000 6.4475000 -1.147500e+00
## 10 138 Glucosa en ayunas (mM) 5.42000 6.6941667 -1.274167e+00
## 11 138 Alanina aminotransferasa (U/L) 40.00000 29.8800000 1.012000e+01
## 12 138 Aspartato aminotransferasa (U/L) 24.00000 24.9828333 -9.828333e-01
## 13 138 Urea (mM) 5.54000 6.4457000 -9.057000e-01
## 14 138 Creatinina (µM) 55.00000 67.9600000 -1.296000e+01
## 15 138 Ácido úrico (µM) 334.00000 343.1596667 -9.159667e+00
## 16 138 Albúmina (g/L) 45.60000 75.9840000 -3.038400e+01
## 17 138 Colesterol total (mM) 29.10000 5.2225000 2.387750e+01
## 18 138 Triglicéridos (mM) 1.28000 1.7142333 -4.342333e-01
## 19 138 Colesterol LDL (mM) 2.35000 2.7575333 -4.075333e-01
## 20 138 Fosfatasa alcalina (U/L) 69.00000 75.6668333 -6.666833e+00
## 21 138 Υ-GT (U/L) 33.00000 34.9866667 -1.986667e+00
## 22 138 Bilirrubina total (µM) 12.80000 14.6566667 -1.856667e+00
## 23 138 Ácidos biliares totales (µM) 2.90000 2.8940000 6.000000e-03
## 24 138 Colinesterasa (U/L) 308.00000 391.9466667 -8.394667e+01
## 25 138 Leucocitos (10^9/L) 6.23000 8.0054000 -1.775400e+00
## 26 138 Neutrófilos (%) 54.50000 56.6200000 -2.120000e+00
## 27 138 Linfocitos (%) 37.90000 45.4336667 -7.533667e+00
## 28 138 Eosinófilos (%) 0.30000 2.1063667 -1.806367e+00
## 29 138 Basófilos (%) 0.20000 0.4947667 -2.947667e-01
## 30 4 Grupo 1.00000 1.6666667 -6.666667e-01
## 31 4 Edad 34.00000 48.1033333 -1.410333e+01
## 32 4 Altura 178.00000 168.9810000 9.019000e+00
## 33 4 Peso 68.00000 72.0360000 -4.036000e+00
## 34 4 Índice de masa corporal (kg/m²) 21.46000 25.1264947 -3.666495e+00
## 35 4 Circunferencia de cintura (cm) 96.00000 84.4100000 1.159000e+01
## 36 4 Presión sistólica (mm Hg) 126.00000 126.9833333 -9.833333e-01
## 37 4 Presión diastólica (mm Hg) 94.00000 78.7066667 1.529333e+01
## 38 4 Hemoglobina A1c (%) 11.50000 6.4475000 5.052500e+00
## 39 4 Glucosa en ayunas (mM) 12.35000 6.6941667 5.655833e+00
## 40 4 Alanina aminotransferasa (U/L) 703.00000 29.8800000 6.731200e+02
## 41 4 Aspartato aminotransferasa (U/L) 292.00000 24.9828333 2.670172e+02
## 42 4 Urea (mM) 3.58000 6.4457000 -2.865700e+00
## 43 4 Creatinina (µM) 52.00000 67.9600000 -1.596000e+01
## 44 4 Ácido úrico (µM) 337.00000 343.1596667 -6.159667e+00
## 45 4 Albúmina (g/L) 44.60000 75.9840000 -3.138400e+01
## 46 4 Colesterol total (mM) 4.45000 5.2225000 -7.725000e-01
## 47 4 Triglicéridos (mM) 1.39000 1.7142333 -3.242333e-01
## 48 4 Colesterol LDL (mM) 2.63000 2.7575333 -1.275333e-01
## 49 4 Fosfatasa alcalina (U/L) 89.00000 75.6668333 1.333317e+01
## 50 4 Υ-GT (U/L) 195.00000 34.9866667 1.600133e+02
## 51 4 Bilirrubina total (µM) 16.70000 14.6566667 2.043333e+00
## 52 4 Ácidos biliares totales (µM) 3.70000 2.8940000 8.060000e-01
## 53 4 Colinesterasa (U/L) 450.00000 391.9466667 5.805333e+01
## 54 4 Leucocitos (10^9/L) 6.36000 8.0054000 -1.645400e+00
## 55 4 Neutrófilos (%) 37.60000 56.6200000 -1.902000e+01
## 56 4 Linfocitos (%) 54.60000 45.4336667 9.166333e+00
## 57 4 Eosinófilos (%) 1.30000 2.1063667 -8.063667e-01
## 58 4 Basófilos (%) 0.50000 0.4947667 5.233333e-03
## 59 23 Grupo 1.00000 1.6666667 -6.666667e-01
## 60 23 Edad 35.00000 48.1033333 -1.310333e+01
## 61 23 Altura 180.00000 168.9810000 1.101900e+01
## 62 23 Peso 113.40000 72.0360000 4.136400e+01
## 63 23 Índice de masa corporal (kg/m²) 35.00000 25.1264947 9.873505e+00
## 64 23 Circunferencia de cintura (cm) 117.00000 84.4100000 3.259000e+01
## 65 23 Presión sistólica (mm Hg) 152.00000 126.9833333 2.501667e+01
## 66 23 Presión diastólica (mm Hg) 86.00000 78.7066667 7.293333e+00
## 67 23 Hemoglobina A1c (%) 8.90000 6.4475000 2.452500e+00
## 68 23 Glucosa en ayunas (mM) 10.39000 6.6941667 3.695833e+00
## 69 23 Alanina aminotransferasa (U/L) 302.00000 29.8800000 2.721200e+02
## 70 23 Aspartato aminotransferasa (U/L) 275.00000 24.9828333 2.500172e+02
## 71 23 Urea (mM) 3.60000 6.4457000 -2.845700e+00
## 72 23 Creatinina (µM) 55.00000 67.9600000 -1.296000e+01
## 73 23 Ácido úrico (µM) 402.00000 343.1596667 5.884033e+01
## 74 23 Albúmina (g/L) 42.90000 75.9840000 -3.308400e+01
## 75 23 Colesterol total (mM) 8.72000 5.2225000 3.497500e+00
## 76 23 Triglicéridos (mM) 4.10000 1.7142333 2.385767e+00
## 77 23 Colesterol LDL (mM) 5.36000 2.7575333 2.602467e+00
## 78 23 Fosfatasa alcalina (U/L) 110.00000 75.6668333 3.433317e+01
## 79 23 Υ-GT (U/L) 261.00000 34.9866667 2.260133e+02
## 80 23 Bilirrubina total (µM) 19.40000 14.6566667 4.743333e+00
## 81 23 Ácidos biliares totales (µM) 3.90000 2.8940000 1.006000e+00
## 82 23 Colinesterasa (U/L) 530.00000 391.9466667 1.380533e+02
## 83 23 Leucocitos (10^9/L) 5.83000 8.0054000 -2.175400e+00
## 84 23 Neutrófilos (%) 51.50000 56.6200000 -5.120000e+00
## 85 23 Linfocitos (%) 34.10000 45.4336667 -1.133367e+01
## 86 23 Eosinófilos (%) 5.50000 2.1063667 3.393633e+00
## 87 23 Basófilos (%) 1.20000 0.4947667 7.052333e-01
## 88 43 Grupo 1.00000 1.6666667 -6.666667e-01
## 89 43 Edad 36.00000 48.1033333 -1.210333e+01
## 90 43 Altura 165.00000 168.9810000 -3.981000e+00
## 91 43 Peso 70.00000 72.0360000 -2.036000e+00
## 92 43 Índice de masa corporal (kg/m²) 25.71166 25.1264947 5.851674e-01
## 93 43 Circunferencia de cintura (cm) 83.00000 84.4100000 -1.410000e+00
## 94 43 Presión sistólica (mm Hg) 137.00000 126.9833333 1.001667e+01
## 95 43 Presión diastólica (mm Hg) 80.00000 78.7066667 1.293333e+00
## 96 43 Hemoglobina A1c (%) 6.51000 6.4475000 6.250000e-02
## 97 43 Glucosa en ayunas (mM) 8.52000 6.6941667 1.825833e+00
## 98 43 Alanina aminotransferasa (U/L) 181.00000 29.8800000 1.511200e+02
## 99 43 Aspartato aminotransferasa (U/L) 168.00000 24.9828333 1.430172e+02
## 100 43 Urea (mM) 2.82000 6.4457000 -3.625700e+00
## 101 43 Creatinina (µM) 51.00000 67.9600000 -1.696000e+01
## 102 43 Ácido úrico (µM) 372.00000 343.1596667 2.884033e+01
## 103 43 Albúmina (g/L) 50.30000 75.9840000 -2.568400e+01
## 104 43 Colesterol total (mM) 6.19000 5.2225000 9.675000e-01
## 105 43 Triglicéridos (mM) 6.51000 1.7142333 4.795767e+00
## 106 43 Colesterol LDL (mM) 3.65000 2.7575333 8.924667e-01
## 107 43 Fosfatasa alcalina (U/L) 72.00000 75.6668333 -3.666833e+00
## 108 43 Υ-GT (U/L) 120.00000 34.9866667 8.501333e+01
## 109 43 Bilirrubina total (µM) 18.00000 14.6566667 3.343333e+00
## 110 43 Ácidos biliares totales (µM) 12.10000 2.8940000 9.206000e+00
## 111 43 Colinesterasa (U/L) 425.00000 391.9466667 3.305333e+01
## 112 43 Leucocitos (10^9/L) 10.50000 8.0054000 2.494600e+00
## 113 43 Neutrófilos (%) 53.00000 56.6200000 -3.620000e+00
## 114 43 Linfocitos (%) 37.30000 45.4336667 -8.133667e+00
## 115 43 Eosinófilos (%) 3.20000 2.1063667 1.093633e+00
## 116 43 Basófilos (%) 0.90000 0.4947667 4.052333e-01
## 117 153 Grupo 2.00000 1.6666667 3.333333e-01
## 118 153 Edad 54.00000 48.1033333 5.896667e+00
## 119 153 Altura 157.00000 168.9810000 -1.198100e+01
## 120 153 Peso 41.10000 72.0360000 -3.093600e+01
## 121 153 Índice de masa corporal (kg/m²) 16.67410 25.1264947 -8.452390e+00
## 122 153 Circunferencia de cintura (cm) 59.00000 84.4100000 -2.541000e+01
## 123 153 Presión sistólica (mm Hg) 108.00000 126.9833333 -1.898333e+01
## 124 153 Presión diastólica (mm Hg) 77.00000 78.7066667 -1.706667e+00
## 125 153 Hemoglobina A1c (%) 5.80000 6.4475000 -6.475000e-01
## 126 153 Glucosa en ayunas (mM) 4.49000 6.6941667 -2.204167e+00
## 127 153 Alanina aminotransferasa (U/L) 13.00000 29.8800000 -1.688000e+01
## 128 153 Aspartato aminotransferasa (U/L) 23.00000 24.9828333 -1.982833e+00
## 129 153 Urea (mM) 397.00000 6.4457000 3.905543e+02
## 130 153 Creatinina (µM) 64.00000 67.9600000 -3.960000e+00
## 131 153 Ácido úrico (µM) 234.00000 343.1596667 -1.091597e+02
## 132 153 Albúmina (g/L) 48.30000 75.9840000 -2.768400e+01
## 133 153 Colesterol total (mM) 6.15000 5.2225000 9.275000e-01
## 134 153 Triglicéridos (mM) 1.12000 1.7142333 -5.942333e-01
## 135 153 Colesterol LDL (mM) 3.12000 2.7575333 3.624667e-01
## 136 153 Fosfatasa alcalina (U/L) 130.00000 75.6668333 5.433317e+01
## 137 153 Υ-GT (U/L) 15.00000 34.9866667 -1.998667e+01
## 138 153 Bilirrubina total (µM) 12.80000 14.6566667 -1.856667e+00
## 139 153 Ácidos biliares totales (µM) 2.10000 2.8940000 -7.940000e-01
## 140 153 Colinesterasa (U/L) 300.00000 391.9466667 -9.194667e+01
## 141 153 Leucocitos (10^9/L) 5.47000 8.0054000 -2.535400e+00
## 142 153 Neutrófilos (%) 60.80000 56.6200000 4.180000e+00
## 143 153 Linfocitos (%) 34.00000 45.4336667 -1.143367e+01
## 144 153 Eosinófilos (%) 0.70000 2.1063667 -1.406367e+00
## 145 153 Basófilos (%) 0.50000 0.4947667 5.233333e-03
## 146 187 Grupo 2.00000 1.6666667 3.333333e-01
## 147 187 Edad 42.00000 48.1033333 -6.103333e+00
## 148 187 Altura 185.00000 168.9810000 1.601900e+01
## 149 187 Peso 102.00000 72.0360000 2.996400e+01
## 150 187 Índice de masa corporal (kg/m²) 29.80278 25.1264947 4.676281e+00
## 151 187 Circunferencia de cintura (cm) 99.00000 84.4100000 1.459000e+01
## 152 187 Presión sistólica (mm Hg) 126.00000 126.9833333 -9.833333e-01
## 153 187 Presión diastólica (mm Hg) 79.00000 78.7066667 2.933333e-01
## 154 187 Hemoglobina A1c (%) 5.60000 6.4475000 -8.475000e-01
## 155 187 Glucosa en ayunas (mM) 30.00000 6.6941667 2.330583e+01
## 156 187 Alanina aminotransferasa (U/L) 25.00000 29.8800000 -4.880000e+00
## 157 187 Aspartato aminotransferasa (U/L) 0.85000 24.9828333 -2.413283e+01
## 158 187 Urea (mM) 5.50000 6.4457000 -9.457000e-01
## 159 187 Creatinina (µM) 855.00000 67.9600000 7.870400e+02
## 160 187 Ácido úrico (µM) 401.00000 343.1596667 5.784033e+01
## 161 187 Albúmina (g/L) 47.00000 75.9840000 -2.898400e+01
## 162 187 Colesterol total (mM) 5.11000 5.2225000 -1.125000e-01
## 163 187 Triglicéridos (mM) 3.23000 1.7142333 1.515767e+00
## 164 187 Colesterol LDL (mM) 2.76000 2.7575333 2.466667e-03
## 165 187 Fosfatasa alcalina (U/L) 67.00000 75.6668333 -8.666833e+00
## 166 187 Υ-GT (U/L) 18.00000 34.9866667 -1.698667e+01
## 167 187 Bilirrubina total (µM) 12.90000 14.6566667 -1.756667e+00
## 168 187 Ácidos biliares totales (µM) 2.10000 2.8940000 -7.940000e-01
## 169 187 Colinesterasa (U/L) 468.00000 391.9466667 7.605333e+01
## 170 187 Leucocitos (10^9/L) 6.23000 8.0054000 -1.775400e+00
## 171 187 Neutrófilos (%) 63.50000 56.6200000 6.880000e+00
## 172 187 Linfocitos (%) 27.80000 45.4336667 -1.763367e+01
## 173 187 Eosinófilos (%) 1.60000 2.1063667 -5.063667e-01
## 174 187 Basófilos (%) 0.20000 0.4947667 -2.947667e-01
## 175 230 Grupo 2.00000 1.6666667 3.333333e-01
## 176 230 Edad 47.00000 48.1033333 -1.103333e+00
## 177 230 Altura 172.00000 168.9810000 3.019000e+00
## 178 230 Peso 58.80000 72.0360000 -1.323600e+01
## 179 230 Índice de masa corporal (kg/m²) 19.87561 25.1264947 -5.250886e+00
## 180 230 Circunferencia de cintura (cm) 75.00000 84.4100000 -9.410000e+00
## 181 230 Presión sistólica (mm Hg) 131.00000 126.9833333 4.016667e+00
## 182 230 Presión diastólica (mm Hg) 74.00000 78.7066667 -4.706667e+00
## 183 230 Hemoglobina A1c (%) 5.40000 6.4475000 -1.047500e+00
## 184 230 Glucosa en ayunas (mM) 5.20000 6.6941667 -1.494167e+00
## 185 230 Alanina aminotransferasa (U/L) 11.00000 29.8800000 -1.888000e+01
## 186 230 Aspartato aminotransferasa (U/L) 11.00000 24.9828333 -1.398283e+01
## 187 230 Urea (mM) 3.21000 6.4457000 -3.235700e+00
## 188 230 Creatinina (µM) 43.00000 67.9600000 -2.496000e+01
## 189 230 Ácido úrico (µM) 203.00000 343.1596667 -1.401597e+02
## 190 230 Albúmina (g/L) 4401.00000 75.9840000 4.325016e+03
## 191 230 Colesterol total (mM) 4.80000 5.2225000 -4.225000e-01
## 192 230 Triglicéridos (mM) 0.96000 1.7142333 -7.542333e-01
## 193 230 Colesterol LDL (mM) 2.26000 2.7575333 -4.975333e-01
## 194 230 Fosfatasa alcalina (U/L) 44.00000 75.6668333 -3.166683e+01
## 195 230 Υ-GT (U/L) 17.00000 34.9866667 -1.798667e+01
## 196 230 Bilirrubina total (µM) 8.20000 14.6566667 -6.456667e+00
## 197 230 Ácidos biliares totales (µM) 4.80000 2.8940000 1.906000e+00
## 198 230 Colinesterasa (U/L) 284.00000 391.9466667 -1.079467e+02
## 199 230 Leucocitos (10^9/L) 4.55000 8.0054000 -3.455400e+00
## 200 230 Neutrófilos (%) 53.10000 56.6200000 -3.520000e+00
## 201 230 Linfocitos (%) 37.80000 45.4336667 -7.633667e+00
## 202 230 Eosinófilos (%) 0.40000 2.1063667 -1.706367e+00
## 203 230 Basófilos (%) 0.40000 0.4947667 -9.476667e-02
## 204 298 Grupo 2.00000 1.6666667 3.333333e-01
## 205 298 Edad 44.00000 48.1033333 -4.103333e+00
## 206 298 Altura 177.00000 168.9810000 8.019000e+00
## 207 298 Peso 83.60000 72.0360000 1.156400e+01
## 208 298 Índice de masa corporal (kg/m²) 26.68454 25.1264947 1.558047e+00
## 209 298 Circunferencia de cintura (cm) 90.00000 84.4100000 5.590000e+00
## 210 298 Presión sistólica (mm Hg) 130.00000 126.9833333 3.016667e+00
## 211 298 Presión diastólica (mm Hg) 88.00000 78.7066667 9.293333e+00
## 212 298 Hemoglobina A1c (%) 5.70000 6.4475000 -7.475000e-01
## 213 298 Glucosa en ayunas (mM) 5.03000 6.6941667 -1.664167e+00
## 214 298 Alanina aminotransferasa (U/L) 43.00000 29.8800000 1.312000e+01
## 215 298 Aspartato aminotransferasa (U/L) 29.00000 24.9828333 4.017167e+00
## 216 298 Urea (mM) 5.33000 6.4457000 -1.115700e+00
## 217 298 Creatinina (µM) 77.00000 67.9600000 9.040000e+00
## 218 298 Ácido úrico (µM) 392.00000 343.1596667 4.884033e+01
## 219 298 Albúmina (g/L) 4701.00000 75.9840000 4.625016e+03
## 220 298 Colesterol total (mM) 7.01000 5.2225000 1.787500e+00
## 221 298 Triglicéridos (mM) 1.75000 1.7142333 3.576667e-02
## 222 298 Colesterol LDL (mM) 4.30000 2.7575333 1.542467e+00
## 223 298 Fosfatasa alcalina (U/L) 54.00000 75.6668333 -2.166683e+01
## 224 298 Υ-GT (U/L) 19.00000 34.9866667 -1.598667e+01
## 225 298 Bilirrubina total (µM) 12.50000 14.6566667 -2.156667e+00
## 226 298 Ácidos biliares totales (µM) 2.00000 2.8940000 -8.940000e-01
## 227 298 Colinesterasa (U/L) 449.00000 391.9466667 5.705333e+01
## 228 298 Leucocitos (10^9/L) 4.69000 8.0054000 -3.315400e+00
## 229 298 Neutrófilos (%) 54.70000 56.6200000 -1.920000e+00
## 230 298 Linfocitos (%) 39.00000 45.4336667 -6.433667e+00
## 231 298 Eosinófilos (%) 0.60000 2.1063667 -1.506367e+00
## 232 298 Basófilos (%) 0.60000 0.4947667 1.052333e-01
## 233 225 Grupo 2.00000 1.6666667 3.333333e-01
## 234 225 Edad 63.00000 48.1033333 1.489667e+01
## 235 225 Altura 168.50000 168.9810000 -4.810000e-01
## 236 225 Peso 73.80000 72.0360000 1.764000e+00
## 237 225 Índice de masa corporal (kg/m²) 25.99301 25.1264947 8.665140e-01
## 238 225 Circunferencia de cintura (cm) 90.00000 84.4100000 5.590000e+00
## 239 225 Presión sistólica (mm Hg) 132.00000 126.9833333 5.016667e+00
## 240 225 Presión diastólica (mm Hg) 85.00000 78.7066667 6.293333e+00
## 241 225 Hemoglobina A1c (%) 5.30000 6.4475000 -1.147500e+00
## 242 225 Glucosa en ayunas (mM) 5.08000 6.6941667 -1.614167e+00
## 243 225 Alanina aminotransferasa (U/L) 17.00000 29.8800000 -1.288000e+01
## 244 225 Aspartato aminotransferasa (U/L) 16.00000 24.9828333 -8.982833e+00
## 245 225 Urea (mM) 3.50000 6.4457000 -2.945700e+00
## 246 225 Creatinina (µM) 76.00000 67.9600000 8.040000e+00
## 247 225 Ácido úrico (µM) 372.00000 343.1596667 2.884033e+01
## 248 225 Albúmina (g/L) 42.50000 75.9840000 -3.348400e+01
## 249 225 Colesterol total (mM) 3.83000 5.2225000 -1.392500e+00
## 250 225 Triglicéridos (mM) 1.05000 1.7142333 -6.642333e-01
## 251 225 Colesterol LDL (mM) 2.04000 2.7575333 -7.175333e-01
## 252 225 Fosfatasa alcalina (U/L) 84.00000 75.6668333 8.333167e+00
## 253 225 Υ-GT (U/L) 28.00000 34.9866667 -6.986667e+00
## 254 225 Bilirrubina total (µM) 34.10000 14.6566667 1.944333e+01
## 255 225 Ácidos biliares totales (µM) 1.70000 2.8940000 -1.194000e+00
## 256 225 Colinesterasa (U/L) 288.00000 391.9466667 -1.039467e+02
## 257 225 Leucocitos (10^9/L) 628.00000 8.0054000 6.199946e+02
## 258 225 Neutrófilos (%) 60.00000 56.6200000 3.380000e+00
## 259 225 Linfocitos (%) 30.50000 45.4336667 -1.493367e+01
## 260 225 Eosinófilos (%) 1.10000 2.1063667 -1.006367e+00
## 261 225 Basófilos (%) 0.50000 0.4947667 5.233333e-03
## 262 276 Grupo 2.00000 1.6666667 3.333333e-01
## 263 276 Edad 43.00000 48.1033333 -5.103333e+00
## 264 276 Altura 174.50000 168.9810000 5.519000e+00
## 265 276 Peso 79.40000 72.0360000 7.364000e+00
## 266 276 Índice de masa corporal (kg/m²) 26.07532 25.1264947 9.488249e-01
## 267 276 Circunferencia de cintura (cm) 90.00000 84.4100000 5.590000e+00
## 268 276 Presión sistólica (mm Hg) 124.00000 126.9833333 -2.983333e+00
## 269 276 Presión diastólica (mm Hg) 77.00000 78.7066667 -1.706667e+00
## 270 276 Hemoglobina A1c (%) 5.30000 6.4475000 -1.147500e+00
## 271 276 Glucosa en ayunas (mM) 4.94000 6.6941667 -1.754167e+00
## 272 276 Alanina aminotransferasa (U/L) 31.00000 29.8800000 1.120000e+00
## 273 276 Aspartato aminotransferasa (U/L) 25.00000 24.9828333 1.716667e-02
## 274 276 Urea (mM) 6.68000 6.4457000 2.343000e-01
## 275 276 Creatinina (µM) 85.00000 67.9600000 1.704000e+01
## 276 276 Ácido úrico (µM) 402.00000 343.1596667 5.884033e+01
## 277 276 Albúmina (g/L) 48.00000 75.9840000 -2.798400e+01
## 278 276 Colesterol total (mM) 5.87000 5.2225000 6.475000e-01
## 279 276 Triglicéridos (mM) 1.57000 1.7142333 -1.442333e-01
## 280 276 Colesterol LDL (mM) 3.56000 2.7575333 8.024667e-01
## 281 276 Fosfatasa alcalina (U/L) 85.00000 75.6668333 9.333167e+00
## 282 276 Υ-GT (U/L) 37.00000 34.9866667 2.013333e+00
## 283 276 Bilirrubina total (µM) 16.90000 14.6566667 2.243333e+00
## 284 276 Ácidos biliares totales (µM) 2.80000 2.8940000 -9.400000e-02
## 285 276 Colinesterasa (U/L) 435.00000 391.9466667 4.305333e+01
## 286 276 Leucocitos (10^9/L) 5.48000 8.0054000 -2.525400e+00
## 287 276 Neutrófilos (%) 52.40000 56.6200000 -4.220000e+00
## 288 276 Linfocitos (%) 3401.00000 45.4336667 3.355566e+03
## 289 276 Eosinófilos (%) 6.20000 2.1063667 4.093633e+00
## 290 276 Basófilos (%) 0.50000 0.4947667 5.233333e-03
Imputación de datos con MICE
#crear copia baseline1
baseline1_filtrada <- Baseline_sin_errores %>%
filter(`WBC (10^9/L)` != 628.00)
#crear una fila con NA
nueva_fila <- baseline1_filtrada[1, ]
nueva_fila$`WBC (10^9/L)` <- NA
baseline_temp <- bind_rows(baseline1_filtrada, nueva_fila)
#Mice
metodos <- make.method(baseline_temp)
metodos[] <- ""
metodos["WBC (10^9/L)"] <- "pmm"
imp <- mice(baseline_temp, method = metodos, m = 5, maxit = 10, seed = 123)
##
## iter imp variable
## 1 1 WBC (10^9/L)
## 1 2 WBC (10^9/L)
## 1 3 WBC (10^9/L)
## 1 4 WBC (10^9/L)
## 1 5 WBC (10^9/L)
## 2 1 WBC (10^9/L)
## 2 2 WBC (10^9/L)
## 2 3 WBC (10^9/L)
## 2 4 WBC (10^9/L)
## 2 5 WBC (10^9/L)
## 3 1 WBC (10^9/L)
## 3 2 WBC (10^9/L)
## 3 3 WBC (10^9/L)
## 3 4 WBC (10^9/L)
## 3 5 WBC (10^9/L)
## 4 1 WBC (10^9/L)
## 4 2 WBC (10^9/L)
## 4 3 WBC (10^9/L)
## 4 4 WBC (10^9/L)
## 4 5 WBC (10^9/L)
## 5 1 WBC (10^9/L)
## 5 2 WBC (10^9/L)
## 5 3 WBC (10^9/L)
## 5 4 WBC (10^9/L)
## 5 5 WBC (10^9/L)
## 6 1 WBC (10^9/L)
## 6 2 WBC (10^9/L)
## 6 3 WBC (10^9/L)
## 6 4 WBC (10^9/L)
## 6 5 WBC (10^9/L)
## 7 1 WBC (10^9/L)
## 7 2 WBC (10^9/L)
## 7 3 WBC (10^9/L)
## 7 4 WBC (10^9/L)
## 7 5 WBC (10^9/L)
## 8 1 WBC (10^9/L)
## 8 2 WBC (10^9/L)
## 8 3 WBC (10^9/L)
## 8 4 WBC (10^9/L)
## 8 5 WBC (10^9/L)
## 9 1 WBC (10^9/L)
## 9 2 WBC (10^9/L)
## 9 3 WBC (10^9/L)
## 9 4 WBC (10^9/L)
## 9 5 WBC (10^9/L)
## 10 1 WBC (10^9/L)
## 10 2 WBC (10^9/L)
## 10 3 WBC (10^9/L)
## 10 4 WBC (10^9/L)
## 10 5 WBC (10^9/L)
## Warning: Number of logged events: 4
#imprimir los valores imputados
imp$imp$`WBC (10^9/L)`
#crear copia baseline2
baseline2_filtrada <- Baseline_sin_errores %>%
filter(`LYMPH (%)` != 3401.00)
#crear una fila con NA
nueva_fila <- baseline2_filtrada[1, ]
nueva_fila$`LYMPH (%)` <- NA
baseline_temp <- bind_rows(baseline2_filtrada, nueva_fila)
#Mice
metodos <- make.method(baseline_temp)
metodos[] <- ""
metodos["LYMPH (%)"] <- "pmm"
imp <- mice(baseline_temp, method = metodos, m = 5, maxit = 10, seed = 123)
##
## iter imp variable
## 1 1 LYMPH (%)
## 1 2 LYMPH (%)
## 1 3 LYMPH (%)
## 1 4 LYMPH (%)
## 1 5 LYMPH (%)
## 2 1 LYMPH (%)
## 2 2 LYMPH (%)
## 2 3 LYMPH (%)
## 2 4 LYMPH (%)
## 2 5 LYMPH (%)
## 3 1 LYMPH (%)
## 3 2 LYMPH (%)
## 3 3 LYMPH (%)
## 3 4 LYMPH (%)
## 3 5 LYMPH (%)
## 4 1 LYMPH (%)
## 4 2 LYMPH (%)
## 4 3 LYMPH (%)
## 4 4 LYMPH (%)
## 4 5 LYMPH (%)
## 5 1 LYMPH (%)
## 5 2 LYMPH (%)
## 5 3 LYMPH (%)
## 5 4 LYMPH (%)
## 5 5 LYMPH (%)
## 6 1 LYMPH (%)
## 6 2 LYMPH (%)
## 6 3 LYMPH (%)
## 6 4 LYMPH (%)
## 6 5 LYMPH (%)
## 7 1 LYMPH (%)
## 7 2 LYMPH (%)
## 7 3 LYMPH (%)
## 7 4 LYMPH (%)
## 7 5 LYMPH (%)
## 8 1 LYMPH (%)
## 8 2 LYMPH (%)
## 8 3 LYMPH (%)
## 8 4 LYMPH (%)
## 8 5 LYMPH (%)
## 9 1 LYMPH (%)
## 9 2 LYMPH (%)
## 9 3 LYMPH (%)
## 9 4 LYMPH (%)
## 9 5 LYMPH (%)
## 10 1 LYMPH (%)
## 10 2 LYMPH (%)
## 10 3 LYMPH (%)
## 10 4 LYMPH (%)
## 10 5 LYMPH (%)
## Warning: Number of logged events: 4
#imprimir los valores imputados
imp$imp$`LYMPH (%)`
Tabla 1
Baseline
baseline <- Basecom %>% select(3:34)
# Diccionario de nombres
diccionario = c(
Gender = "Sexo",
Group = "Grupo",
Age = "Edad",
Height = "Altura",
Weight = "Peso",
BMI = "Índice de masa corporal (kg/m²)",
`Waistline (cm)` = "Circunferencia de cintura (cm)",
`SBP (mmHg)` = "Presión sistólica (mm Hg)",
`DBP (mmHg)` = "Presión diastólica (mm Hg)",
`HBA (%)` = "Hemoglobina A1c (%)",
`FBG (mM)` = "Glucosa en ayunas (mM)",
`ALT (U/L)` = "Alanina aminotransferasa (U/L)",
`AST (U/L)` = "Aspartato aminotransferasa (U/L)",
`Urea (mM)` = "Urea (mM)",
`Cre (uM)` = "Creatinina (µM)",
`UA (uM)` = "Ácido úrico (µM)",
`ALB (g/L)` = "Albúmina (g/L)",
`TC (mM)` = "Colesterol total (mM)",
`TG (mM)` = "Triglicéridos (mM)",
`HDL-C (mM)` = "Colesterol HDL (mM)",
`LDL-C (mM)` = "Colesterol LDL (mM)",
`ALP (U/L)` = "Fosfatasa alcalina (U/L)",
#`Υ-GT (U/L)` = "Gamma-GT (U/L)",
`T-BIL (uM)` = "Bilirrubina total (µM)",
`D-BIL (uM)` = "Bilirrubina directa (µM)",
`TBA (uM)` = "Ácidos biliares totales (µM)",
`CHE (U/L)` = "Colinesterasa (U/L)",
`WBC (10^9/L)` = "Leucocitos (10^9/L)",
`NEUT (%)` = "Neutrófilos (%)",
`LYMPH (%)` = "Linfocitos (%)",
`EO (%)` = "Eosinófilos (%)",
`BASO (%)` = "Basófilos (%)"
)
# Renombrar variables usando el diccionario
nombres_originales = names(baseline)
nombres_nuevos = sapply(nombres_originales, function(nombre) {
if (nombre %in% names(diccionario)) {
diccionario[[nombre]]
} else {
nombre # conservar si no está en el diccionario
}
})
names(baseline) = nombres_nuevos
baseline$`Edad categorizada` <- cut(
baseline$Edad,
breaks = c(18, 40, 60, 80, 100),
right = TRUE, # para incluir el límite de rango
labels = c("18–40", "41–60", "61–80", "81–100")
)
# Traduce la variable "Grupo" a etiquetas legibles
baseline <- baseline %>%
mutate(Grupo = case_when(
Grupo == 1 ~ "T2D",
Grupo == 2 ~ "sin T2D",
TRUE ~ as.character(Grupo)
))
# variables continuas y categóricas
vars_continuas <- c("Edad", "Altura", "Peso", "Índice de masa corporal (kg/m²)",
"Circunferencia de cintura (cm)", "Presión sistólica (mm Hg)",
"Presión diastólica (mm Hg)", "Glucosa en ayunas (mM)",
"Colesterol total (mM)", "Triglicéridos (mM)",
"Colesterol HDL (mM)", "Colesterol LDL (mM)",
"Alanina aminotransferasa (U/L)", "Aspartato aminotransferasa (U/L)",
"Urea (mM)", "Creatinina (µM)", "Ácido úrico (µM)", "Albúmina (g/L)",
"Fosfatasa alcalina (U/L)", "Bilirrubina total (µM)",
"Bilirrubina directa (µM)", "Ácidos biliares totales (µM)",
"Colinesterasa (U/L)", "Leucocitos (10^9/L)", "Υ-GT (U/L)")
vars_categoricas <- c("Sexo")
vars_edad <- "Edad categorizada"
vars_porcentuales <- c("Neutrófilos (%)","Linfocitos (%)","Eosinófilos (%)","Basófilos (%)", "Hemoglobina A1c (%)")
# Crear tabla 1 estratificada por Grupo (1 y 2)
tabla1 <- CreateTableOne(vars = c(vars_categoricas, vars_edad, vars_continuas,
vars_porcentuales), strata = "Grupo",
data = baseline, factorVars = vars_categoricas)
# Imprimir tabla SIN columnas p ni test
tabla1_df <- print(tabla1,
showAllLevels = TRUE,
printToggle = FALSE,
noSpaces = TRUE)
# Eliminar columnas p y test si existen
cols_quitar <- c("p", "test")
cols_presentes <- intersect(cols_quitar, colnames(tabla1_df))
if (length(cols_presentes) > 0) {
tabla1_df <- tabla1_df[, !(colnames(tabla1_df) %in% cols_presentes)]
}
#Imprimir tabla
kable(tabla1_df,
format = "html",
caption = "Tabla 1: Biomarcadores estratificados por grupo") %>%
kable_styling(bootstrap_options = c("striped", "hover", "condensed"),
full_width = FALSE,
position = "center")
Tabla 1: Biomarcadores estratificados por grupo
|
|
level
|
sin T2D
|
T2D
|
|
n
|
|
196
|
97
|
|
Sexo (%)
|
Female
|
97 (49.5)
|
28 (28.9)
|
|
|
Male
|
99 (50.5)
|
69 (71.1)
|
|
Edad categorizada (%)
|
18–40
|
67 (34.2)
|
20 (20.6)
|
|
|
41–60
|
91 (46.4)
|
59 (60.8)
|
|
|
61–80
|
38 (19.4)
|
18 (18.6)
|
|
|
81–100
|
0 (0.0)
|
0 (0.0)
|
|
Edad (mean (SD))
|
|
47.24 (11.64)
|
50.30 (11.74)
|
|
Altura (mean (SD))
|
|
167.90 (8.10)
|
170.84 (8.62)
|
|
Peso (mean (SD))
|
|
67.71 (13.45)
|
80.44 (14.64)
|
|
Índice de masa corporal (kg/m²) (mean (SD))
|
|
23.89 (3.72)
|
27.62 (4.01)
|
|
Circunferencia de cintura (cm) (mean (SD))
|
|
79.97 (10.62)
|
93.09 (9.92)
|
|
Presión sistólica (mm Hg) (mean (SD))
|
|
121.39 (15.68)
|
138.06 (18.57)
|
|
Presión diastólica (mm Hg) (mean (SD))
|
|
74.65 (11.22)
|
86.63 (13.19)
|
|
Glucosa en ayunas (mM) (mean (SD))
|
|
5.01 (0.41)
|
9.79 (3.22)
|
|
Colesterol total (mM) (mean (SD))
|
|
5.16 (1.93)
|
5.30 (1.05)
|
|
Triglicéridos (mM) (mean (SD))
|
|
1.35 (0.76)
|
2.39 (2.12)
|
|
Colesterol HDL (mM) (mean (SD))
|
|
1.47 (0.30)
|
1.34 (0.35)
|
|
Colesterol LDL (mM) (mean (SD))
|
|
2.66 (0.62)
|
2.91 (0.79)
|
|
Alanina aminotransferasa (U/L) (mean (SD))
|
|
20.86 (14.87)
|
37.09 (22.09)
|
|
Aspartato aminotransferasa (U/L) (mean (SD))
|
|
20.75 (6.31)
|
27.10 (15.28)
|
|
Urea (mM) (mean (SD))
|
|
5.06 (1.30)
|
5.37 (1.25)
|
|
Creatinina (µM) (mean (SD))
|
|
65.17 (15.20)
|
66.15 (14.78)
|
|
Ácido úrico (µM) (mean (SD))
|
|
338.93 (99.64)
|
352.33 (116.06)
|
|
Albúmina (g/L) (mean (SD))
|
|
45.63 (3.28)
|
46.57 (3.22)
|
|
Fosfatasa alcalina (U/L) (mean (SD))
|
|
70.39 (19.86)
|
85.96 (24.78)
|
|
Bilirrubina total (µM) (mean (SD))
|
|
14.74 (6.83)
|
14.52 (5.02)
|
|
Bilirrubina directa (µM) (mean (SD))
|
|
3.96 (1.80)
|
3.86 (1.50)
|
|
Ácidos biliares totales (µM) (mean (SD))
|
|
2.75 (2.06)
|
3.08 (1.55)
|
|
Colinesterasa (U/L) (mean (SD))
|
|
361.87 (92.26)
|
451.05 (75.54)
|
|
Leucocitos (10^9/L) (mean (SD))
|
|
5.57 (1.20)
|
6.64 (1.94)
|
|
Υ-GT (U/L) (mean (SD))
|
|
27.92 (26.19)
|
45.13 (24.04)
|
|
Neutrófilos (%) (mean (SD))
|
|
56.27 (7.15)
|
57.56 (6.95)
|
|
Linfocitos (%) (mean (SD))
|
|
35.08 (7.07)
|
32.22 (7.14)
|
|
Eosinófilos (%) (mean (SD))
|
|
2.22 (1.82)
|
1.89 (1.29)
|
|
Basófilos (%) (mean (SD))
|
|
0.49 (0.34)
|
0.50 (0.28)
|
|
Hemoglobina A1c (%) (mean (SD))
|
|
5.46 (0.25)
|
8.39 (2.02)
|
Distancias de mahalanobis - Baseline
##Excluir variables de texto y biomarcadores de diabetes
baseline1 <- Basecom %>% select(14:34)
# vector de medias
center <- colMeans(baseline1)
# matriz de covarianza
cov_matrix <- cov(baseline1)
#distancia de mahalanobis
dist_mahal_bline <- mahalanobis(baseline1, center, cov_matrix)
# Distancias
boxplot(dist_mahal_bline,
main = "Distancia de Mahalanobis",
ylab = "D² (desviaciones multivariadas)",
col = "lightblue")
#95IC
umbral <- qchisq(0.95, df = ncol(baseline1))
#outliers
outliers <- which(dist_mahal_bline > umbral)
outliers
## [1] 11 24 26 27 30 31 32 42 43 44 49 55 57 58 66 67 84 94 97
## [20] 109 112 131 135 145 146 147 163 168 169 196 197 199 239 255 260 265 278
#Grafico
plot(dist_mahal_bline, pch = 19, col = "steelblue",
main = "Distancia de Mahalanobis, primer grupo",
ylab = "D²", xlab = "Observación")
abline(h = umbral, col = "red", lwd = 2, lty = 2)
#Etiquetas para los outliers
text(outliers, dist_mahal_bline[outliers], labels = outliers, pos = 3, col = "red")
Distancias de mahalanobis - M4
M4 <- Basecom %>% select(35:ncol(Basecom))
# vector de medias
center <- colMeans(M4)
# matriz de covarianza
cov_matrix <- cov(M4)
#distancia de mahalanobis
dist_mahal_M4 <- mahalanobis(M4, center, cov_matrix)
# Distancias
boxplot(dist_mahal_M4,
main = "Distancia de Mahalanobis",
ylab = "D² (desviaciones multivariadas)",
col = "lightblue")
#95IC
umbral <- qchisq(0.95, df = ncol(M4))
#outliers
outliers <- which(dist_mahal_M4 > umbral)
outliers
## [1] 2 4 5 7 13 15 17 23 24 26 30 41 43 44 49 51 61 64 66
## [20] 86 88 101 102 103 114 116 118 128 137 138 145 161 165 170 175 185 188 191
## [39] 196 199 216 221 239 250 253 255 257 272 275 279
#Gráfico
plot(dist_mahal_M4, pch = 19, col = "steelblue",
main = "Distancia de Mahalanobis, segundo grupo",
ylab = "D²", xlab = "Observación")
abline(h = umbral, col = "red", lwd = 2, lty = 2)
#Etiquetas para los outliers
text(outliers, dist_mahal_M4[outliers], labels = outliers, pos = 3, col = "red")
Distancias de mahalanobis - Baseline + M4
Bcom <- Basecom %>% select(14:ncol(Basecom))
# vector de medias
center <- colMeans(Bcom)
# matriz de covarianza
cov_matrix <- cov(Bcom)
#distancia de mahalanobis
dist_mahal_Bcom <- mahalanobis(Bcom, center, cov_matrix)
# Distancias
boxplot(dist_mahal_Bcom,
main = "Distancia de Mahalanobis",
ylab = "D² (desviaciones multivariadas)",
col = "lightblue")
#95IC
umbral <- qchisq(0.95, df = ncol(Bcom))
#outliers
outliers <- which(dist_mahal_Bcom > umbral)
outliers
## [1] 2 4 5 7 11 13 15 17 21 24 26 27 30 31 41 43 44 49 51
## [20] 57 64 66 67 101 102 103 116 118 128 131 135 137 141 145 146 147 161 165
## [39] 185 188 191 196 199 221 239 253 255 257 265 272 279
#Gráfico
plot(dist_mahal_Bcom, pch = 19, col = "steelblue",
main = "Distancia de Mahalanobis, tercer grupo",
ylab = "D²", xlab = "Observación")
abline(h = umbral, col = "red", lwd = 2, lty = 2)
#Etiquetas para los outliers
text(outliers, dist_mahal_Bcom[outliers], labels = outliers, pos = 3, col = "red")
Distancias de mahalanobis - Base unida - Both
#Se deben quitar espacios y caracteres especiales de los nombres de cada var
Bcom2 <- Basecom %>% select(13:ncol(Basecom))
names(Bcom2)
## [1] "FBG (mM)"
## [2] "ALT (U/L)"
## [3] "AST (U/L)"
## [4] "Urea (mM)"
## [5] "Cre (uM)"
## [6] "UA (uM)"
## [7] "ALB (g/L)"
## [8] "TC (mM)"
## [9] "TG (mM)"
## [10] "HDL-C (mM)"
## [11] "LDL-C (mM)"
## [12] "ALP (U/L)"
## [13] "Υ-GT (U/L)"
## [14] "T-BIL (uM)"
## [15] "D-BIL (uM)"
## [16] "TBA (uM)"
## [17] "CHE (U/L)"
## [18] "WBC (10^9/L)"
## [19] "NEUT (%)"
## [20] "LYMPH (%)"
## [21] "EO (%)"
## [22] "BASO (%)"
## [23] "Phenylethylamine"
## [24] "Octadecanamide"
## [25] "Urocanic acid"
## [26] "Imidazolepropionic acid"
## [27] "Indole-3-carboxaldehyde"
## [28] "3-Hydroxyanthranilic acid"
## [29] "Dopamine"
## [30] "Oleamide"
## [31] "Oleoylethanolamide"
## [32] "Palmitic amide"
## [33] "Palmitoylethanolamide"
## [34] "Stearoylethanolamide"
## [35] "Bilirubin...47"
## [36] "Biliverdin"
## [37] "Indole-3-acrylic acid"
## [38] "Kynurenic acid"
## [39] "Indole-3-propionic acid"
## [40] "Indole-3-methyl acetate"
## [41] "Dopa"
## [42] "Sphinganine"
## [43] "Sphinganine-1-phosphate"
## [44] "Sphingosine"
## [45] "3-Indolebutyric acid"
## [46] "Sphingosine-1-phosphate"
## [47] "5-Methoxyindoleacetate"
## [48] "Phenylacetylglutamine(PAGln)"
## [49] "Pantothenol"
## [50] "Putrescine"
## [51] "Gamma-aminobutyric acid"
## [52] "5-Aminopentanoic acid"
## [53] "N-Acetylcadaverine"
## [54] "Acetylcholine"
## [55] "Spermidine"
## [56] "N-acetyl-aspartic acid"
## [57] "N8-Acetylspermidine"
## [58] "Spermine"
## [59] "Phenol"
## [60] "p-Cresol"
## [61] "1,5-Anhydrosorbitol"
## [62] "Benzoic acid"
## [63] "Phenylacetic acid"
## [64] "3-Hydroxybenzoic acid"
## [65] "4-Hydroxybenzoic acid"
## [66] "Salicylic acid"
## [67] "3-Hydroxyphenylacetic acid"
## [68] "Phenyllactate"
## [69] "4-Hydroxyphenylpropionate"
## [70] "Bilirubin...82"
## [71] "3-(3-Hydroxyphenyl)-3-hydroxypropanoic acid"
## [72] "4-Hydroxyphenyllactate"
## [73] "p-Cresol sulfate"
## [74] "2-Hydroxy Hippuric Acid"
## [75] "3-Hydroxyhippuric acid"
## [76] "Sphinganine 1-phosphate"
## [77] "Sphingosine 1-phosphate"
## [78] "Cholesterol sulfate"
## [79] "Xanthurenic acid"
## [80] "Cinnamoylglycine"
## [81] "Indoxyl sulfate"
## [82] "Ascorbic acid"
## [83] "p-Cresol glucuronide"
## [84] "Homovanillic acid sulfate"
## [85] "Iodide"
## [86] "Phenyl sulfate"
## [87] "4-Ethylphenyl sulfate"
## [88] "4-Hydroxybenzoic acid-4-O-sulphate"
## [89] "3-Hydroxypropionic acid"
## [90] "Acetylglycine"
## [91] "Hippuric acid"
## [92] "Enterolactone"
names(Bcom2) <- make.names(names(Bcom2))
#Como se repiten nombres y no funciona make.unique
names(Bcom2)[names(Bcom2) == "Sphinganine.1.phosphate"][2] <- "S.ganine.1.phosphate_b"
names(Bcom2)[names(Bcom2) == "Sphingosine.1.phosphate"][2] <- "S.gosine.1.phosphate_b"
#S.ganine = Sphinganine
#S.gosine = Sphingosine
#Modelo
modelo_completo <- lm(FBG..mM. ~ ., data = Bcom2)
#Backward
modelo_both <- step(modelo_completo, direction = "both")
## Start: AIC=336.78
## FBG..mM. ~ ALT..U.L. + AST..U.L. + Urea..mM. + Cre..uM. + UA..uM. +
## ALB..g.L. + TC..mM. + TG..mM. + HDL.C..mM. + LDL.C..mM. +
## ALP..U.L. + Υ.GT..U.L. + T.BIL..uM. + D.BIL..uM. + TBA..uM. +
## CHE..U.L. + WBC..10.9.L. + NEUT.... + LYMPH.... + EO.... +
## BASO.... + Phenylethylamine + Octadecanamide + Urocanic.acid +
## Imidazolepropionic.acid + Indole.3.carboxaldehyde + X3.Hydroxyanthranilic.acid +
## Dopamine + Oleamide + Oleoylethanolamide + Palmitic.amide +
## Palmitoylethanolamide + Stearoylethanolamide + Bilirubin...47 +
## Biliverdin + Indole.3.acrylic.acid + Kynurenic.acid + Indole.3.propionic.acid +
## Indole.3.methyl.acetate + Dopa + Sphinganine + Sphinganine.1.phosphate +
## Sphingosine + X3.Indolebutyric.acid + Sphingosine.1.phosphate +
## X5.Methoxyindoleacetate + Phenylacetylglutamine.PAGln. +
## Pantothenol + Putrescine + Gamma.aminobutyric.acid + X5.Aminopentanoic.acid +
## N.Acetylcadaverine + Acetylcholine + Spermidine + N.acetyl.aspartic.acid +
## N8.Acetylspermidine + Spermine + Phenol + p.Cresol + X1.5.Anhydrosorbitol +
## Benzoic.acid + Phenylacetic.acid + X3.Hydroxybenzoic.acid +
## X4.Hydroxybenzoic.acid + Salicylic.acid + X3.Hydroxyphenylacetic.acid +
## Phenyllactate + X4.Hydroxyphenylpropionate + Bilirubin...82 +
## X3..3.Hydroxyphenyl..3.hydroxypropanoic.acid + X4.Hydroxyphenyllactate +
## p.Cresol.sulfate + X2.Hydroxy.Hippuric.Acid + X3.Hydroxyhippuric.acid +
## S.ganine.1.phosphate_b + S.gosine.1.phosphate_b + Cholesterol.sulfate +
## Xanthurenic.acid + Cinnamoylglycine + Indoxyl.sulfate + Ascorbic.acid +
## p.Cresol.glucuronide + Homovanillic.acid.sulfate + Iodide +
## Phenyl.sulfate + X4.Ethylphenyl.sulfate + X4.Hydroxybenzoic.acid.4.O.sulphate +
## X3.Hydroxypropionic.acid + Acetylglycine + Hippuric.acid +
## Enterolactone
##
## Df Sum of Sq RSS AIC
## - Biliverdin 1 0.000 493.53 334.78
## - Enterolactone 1 0.001 493.54 334.78
## - LDL.C..mM. 1 0.006 493.54 334.78
## - X3.Hydroxyphenylacetic.acid 1 0.009 493.54 334.78
## - Urea..mM. 1 0.010 493.54 334.78
## - Dopamine 1 0.013 493.55 334.78
## - p.Cresol.glucuronide 1 0.017 493.55 334.79
## - BASO.... 1 0.024 493.56 334.79
## - S.gosine.1.phosphate_b 1 0.029 493.56 334.79
## - X4.Hydroxyphenylpropionate 1 0.042 493.58 334.80
## - Dopa 1 0.048 493.58 334.80
## - X4.Ethylphenyl.sulfate 1 0.055 493.59 334.81
## - Oleoylethanolamide 1 0.083 493.62 334.83
## - WBC..10.9.L. 1 0.088 493.62 334.83
## - Phenylacetic.acid 1 0.097 493.63 334.83
## - Υ.GT..U.L. 1 0.098 493.63 334.83
## - Putrescine 1 0.102 493.64 334.84
## - UA..uM. 1 0.105 493.64 334.84
## - TC..mM. 1 0.155 493.69 334.87
## - Sphingosine 1 0.160 493.69 334.87
## - X4.Hydroxybenzoic.acid 1 0.182 493.72 334.88
## - Palmitic.amide 1 0.189 493.72 334.89
## - Sphingosine.1.phosphate 1 0.231 493.77 334.91
## - p.Cresol.sulfate 1 0.249 493.78 334.92
## - CHE..U.L. 1 0.251 493.79 334.93
## - p.Cresol 1 0.302 493.84 334.96
## - Stearoylethanolamide 1 0.328 493.86 334.97
## - Benzoic.acid 1 0.330 493.86 334.97
## - Indole.3.propionic.acid 1 0.424 493.96 335.03
## - X5.Methoxyindoleacetate 1 0.598 494.13 335.13
## - X3.Hydroxybenzoic.acid 1 0.657 494.19 335.17
## - Spermidine 1 0.696 494.23 335.19
## - Spermine 1 0.752 494.29 335.22
## - X4.Hydroxyphenyllactate 1 0.814 494.35 335.26
## - Iodide 1 0.963 494.50 335.35
## - Salicylic.acid 1 1.030 494.56 335.39
## - Hippuric.acid 1 1.248 494.78 335.52
## - Cre..uM. 1 1.408 494.94 335.61
## - Phenol 1 1.586 495.12 335.72
## - X4.Hydroxybenzoic.acid.4.O.sulphate 1 1.653 495.19 335.76
## - Bilirubin...47 1 1.988 495.52 335.95
## - Urocanic.acid 1 2.044 495.58 335.99
## - Bilirubin...82 1 2.204 495.74 336.08
## - ALB..g.L. 1 2.255 495.79 336.11
## - ALP..U.L. 1 2.286 495.82 336.13
## - Indole.3.methyl.acetate 1 2.311 495.84 336.14
## - Acetylcholine 1 2.392 495.93 336.19
## - N8.Acetylspermidine 1 2.455 495.99 336.23
## - Sphinganine.1.phosphate 1 2.507 496.04 336.26
## - N.Acetylcadaverine 1 2.915 496.45 336.50
## - TBA..uM. 1 3.265 496.80 336.71
## - Homovanillic.acid.sulfate 1 3.322 496.86 336.74
## - T.BIL..uM. 1 3.363 496.90 336.77
## <none> 493.53 336.78
## - D.BIL..uM. 1 3.645 497.18 336.93
## - Phenyllactate 1 3.950 497.48 337.11
## - EO.... 1 3.976 497.51 337.13
## - Imidazolepropionic.acid 1 4.082 497.62 337.19
## - Cinnamoylglycine 1 4.382 497.92 337.37
## - X2.Hydroxy.Hippuric.Acid 1 4.470 498.00 337.42
## - Indoxyl.sulfate 1 4.664 498.20 337.53
## - N.acetyl.aspartic.acid 1 5.086 498.62 337.78
## - Phenylacetylglutamine.PAGln. 1 5.114 498.65 337.80
## - Phenylethylamine 1 5.634 499.17 338.10
## - Cholesterol.sulfate 1 5.836 499.37 338.22
## - X3.Hydroxyhippuric.acid 1 6.976 500.51 338.89
## - X3.Hydroxyanthranilic.acid 1 7.176 500.71 339.01
## - Xanthurenic.acid 1 7.379 500.91 339.12
## - Kynurenic.acid 1 7.695 501.23 339.31
## - Oleamide 1 7.730 501.26 339.33
## - Octadecanamide 1 7.757 501.29 339.35
## - Gamma.aminobutyric.acid 1 7.981 501.52 339.48
## - Indole.3.carboxaldehyde 1 8.247 501.78 339.63
## - S.ganine.1.phosphate_b 1 9.563 503.10 340.40
## - Ascorbic.acid 1 10.035 503.57 340.67
## - Sphinganine 1 10.059 503.59 340.69
## - LYMPH.... 1 10.543 504.08 340.97
## - NEUT.... 1 10.825 504.36 341.13
## - AST..U.L. 1 13.051 506.59 342.42
## - X5.Aminopentanoic.acid 1 13.999 507.53 342.97
## - Acetylglycine 1 14.004 507.54 342.97
## - Phenyl.sulfate 1 15.553 509.09 343.87
## - Pantothenol 1 16.617 510.15 344.48
## - ALT..U.L. 1 20.293 513.83 346.58
## - X3.Hydroxypropionic.acid 1 21.420 514.95 347.22
## - X3..3.Hydroxyphenyl..3.hydroxypropanoic.acid 1 22.386 515.92 347.77
## - X1.5.Anhydrosorbitol 1 23.123 516.66 348.19
## - Palmitoylethanolamide 1 23.564 517.10 348.44
## - Indole.3.acrylic.acid 1 23.799 517.33 348.57
## - HDL.C..mM. 1 24.055 517.59 348.72
## - X3.Indolebutyric.acid 1 47.988 541.52 361.96
## - TG..mM. 1 61.771 555.31 369.33
##
## Step: AIC=334.78
## FBG..mM. ~ ALT..U.L. + AST..U.L. + Urea..mM. + Cre..uM. + UA..uM. +
## ALB..g.L. + TC..mM. + TG..mM. + HDL.C..mM. + LDL.C..mM. +
## ALP..U.L. + Υ.GT..U.L. + T.BIL..uM. + D.BIL..uM. + TBA..uM. +
## CHE..U.L. + WBC..10.9.L. + NEUT.... + LYMPH.... + EO.... +
## BASO.... + Phenylethylamine + Octadecanamide + Urocanic.acid +
## Imidazolepropionic.acid + Indole.3.carboxaldehyde + X3.Hydroxyanthranilic.acid +
## Dopamine + Oleamide + Oleoylethanolamide + Palmitic.amide +
## Palmitoylethanolamide + Stearoylethanolamide + Bilirubin...47 +
## Indole.3.acrylic.acid + Kynurenic.acid + Indole.3.propionic.acid +
## Indole.3.methyl.acetate + Dopa + Sphinganine + Sphinganine.1.phosphate +
## Sphingosine + X3.Indolebutyric.acid + Sphingosine.1.phosphate +
## X5.Methoxyindoleacetate + Phenylacetylglutamine.PAGln. +
## Pantothenol + Putrescine + Gamma.aminobutyric.acid + X5.Aminopentanoic.acid +
## N.Acetylcadaverine + Acetylcholine + Spermidine + N.acetyl.aspartic.acid +
## N8.Acetylspermidine + Spermine + Phenol + p.Cresol + X1.5.Anhydrosorbitol +
## Benzoic.acid + Phenylacetic.acid + X3.Hydroxybenzoic.acid +
## X4.Hydroxybenzoic.acid + Salicylic.acid + X3.Hydroxyphenylacetic.acid +
## Phenyllactate + X4.Hydroxyphenylpropionate + Bilirubin...82 +
## X3..3.Hydroxyphenyl..3.hydroxypropanoic.acid + X4.Hydroxyphenyllactate +
## p.Cresol.sulfate + X2.Hydroxy.Hippuric.Acid + X3.Hydroxyhippuric.acid +
## S.ganine.1.phosphate_b + S.gosine.1.phosphate_b + Cholesterol.sulfate +
## Xanthurenic.acid + Cinnamoylglycine + Indoxyl.sulfate + Ascorbic.acid +
## p.Cresol.glucuronide + Homovanillic.acid.sulfate + Iodide +
## Phenyl.sulfate + X4.Ethylphenyl.sulfate + X4.Hydroxybenzoic.acid.4.O.sulphate +
## X3.Hydroxypropionic.acid + Acetylglycine + Hippuric.acid +
## Enterolactone
##
## Df Sum of Sq RSS AIC
## - Enterolactone 1 0.001 493.54 332.78
## - LDL.C..mM. 1 0.006 493.54 332.78
## - X3.Hydroxyphenylacetic.acid 1 0.009 493.54 332.78
## - Urea..mM. 1 0.011 493.55 332.78
## - Dopamine 1 0.013 493.55 332.78
## - p.Cresol.glucuronide 1 0.017 493.55 332.79
## - BASO.... 1 0.024 493.56 332.79
## - S.gosine.1.phosphate_b 1 0.029 493.56 332.79
## - X4.Hydroxyphenylpropionate 1 0.042 493.58 332.80
## - Dopa 1 0.050 493.58 332.81
## - X4.Ethylphenyl.sulfate 1 0.054 493.59 332.81
## - Oleoylethanolamide 1 0.086 493.62 332.83
## - WBC..10.9.L. 1 0.088 493.62 332.83
## - Υ.GT..U.L. 1 0.098 493.63 332.83
## - Phenylacetic.acid 1 0.099 493.63 332.83
## - Putrescine 1 0.102 493.64 332.84
## - UA..uM. 1 0.105 493.64 332.84
## - TC..mM. 1 0.156 493.69 332.87
## - Sphingosine 1 0.160 493.69 332.87
## - X4.Hydroxybenzoic.acid 1 0.182 493.72 332.88
## - Palmitic.amide 1 0.190 493.72 332.89
## - Sphingosine.1.phosphate 1 0.231 493.77 332.91
## - p.Cresol.sulfate 1 0.251 493.78 332.92
## - CHE..U.L. 1 0.251 493.79 332.93
## - p.Cresol 1 0.306 493.84 332.96
## - Benzoic.acid 1 0.332 493.87 332.97
## - Stearoylethanolamide 1 0.333 493.87 332.97
## - Indole.3.propionic.acid 1 0.429 493.96 333.03
## - X5.Methoxyindoleacetate 1 0.604 494.14 333.13
## - X3.Hydroxybenzoic.acid 1 0.660 494.19 333.17
## - Spermidine 1 0.736 494.27 333.21
## - Spermine 1 0.753 494.29 333.22
## - X4.Hydroxyphenyllactate 1 0.818 494.35 333.26
## - Iodide 1 0.963 494.50 333.35
## - Salicylic.acid 1 1.030 494.56 333.39
## - Hippuric.acid 1 1.252 494.79 333.52
## - Cre..uM. 1 1.408 494.94 333.61
## - Phenol 1 1.596 495.13 333.72
## - X4.Hydroxybenzoic.acid.4.O.sulphate 1 1.763 495.30 333.82
## - Bilirubin...47 1 2.016 495.55 333.97
## - Urocanic.acid 1 2.053 495.59 333.99
## - ALP..U.L. 1 2.295 495.83 334.14
## - Indole.3.methyl.acetate 1 2.351 495.89 334.17
## - ALB..g.L. 1 2.393 495.93 334.19
## - Acetylcholine 1 2.393 495.93 334.19
## - N8.Acetylspermidine 1 2.456 495.99 334.23
## - Sphinganine.1.phosphate 1 2.526 496.06 334.27
## - N.Acetylcadaverine 1 2.930 496.46 334.51
## - Bilirubin...82 1 3.160 496.69 334.65
## - TBA..uM. 1 3.267 496.80 334.71
## - Homovanillic.acid.sulfate 1 3.325 496.86 334.74
## <none> 493.53 334.78
## - T.BIL..uM. 1 3.534 497.07 334.87
## - D.BIL..uM. 1 3.650 497.18 334.94
## - EO.... 1 3.980 497.51 335.13
## - Phenyllactate 1 4.072 497.61 335.18
## - Imidazolepropionic.acid 1 4.108 497.64 335.20
## - Cinnamoylglycine 1 4.407 497.94 335.38
## - X2.Hydroxy.Hippuric.Acid 1 4.476 498.01 335.42
## - Indoxyl.sulfate 1 4.785 498.32 335.60
## - N.acetyl.aspartic.acid 1 5.089 498.62 335.78
## - Phenylacetylglutamine.PAGln. 1 5.119 498.65 335.80
## - Phenylethylamine 1 5.643 499.18 336.11
## - Cholesterol.sulfate 1 5.850 499.38 336.23
## + Biliverdin 1 0.000 493.53 336.78
## - X3.Hydroxyhippuric.acid 1 7.153 500.69 336.99
## - X3.Hydroxyanthranilic.acid 1 7.177 500.71 337.01
## - Xanthurenic.acid 1 7.422 500.96 337.15
## - Kynurenic.acid 1 7.778 501.31 337.36
## - Octadecanamide 1 7.834 501.37 337.39
## - Oleamide 1 7.902 501.44 337.43
## - Gamma.aminobutyric.acid 1 7.982 501.52 337.48
## - Indole.3.carboxaldehyde 1 8.260 501.79 337.64
## - S.ganine.1.phosphate_b 1 9.619 503.15 338.43
## - Sphinganine 1 10.283 503.82 338.82
## - Ascorbic.acid 1 10.286 503.82 338.82
## - LYMPH.... 1 10.640 504.17 339.03
## - NEUT.... 1 10.906 504.44 339.18
## - AST..U.L. 1 13.115 506.65 340.46
## - X5.Aminopentanoic.acid 1 14.153 507.69 341.06
## - Acetylglycine 1 14.331 507.86 341.16
## - Phenyl.sulfate 1 15.611 509.15 341.90
## - Pantothenol 1 16.637 510.17 342.49
## - ALT..U.L. 1 20.304 513.84 344.59
## - X3.Hydroxypropionic.acid 1 21.434 514.97 345.23
## - X3..3.Hydroxyphenyl..3.hydroxypropanoic.acid 1 22.478 516.01 345.83
## - X1.5.Anhydrosorbitol 1 23.186 516.72 346.23
## - Indole.3.acrylic.acid 1 23.799 517.33 346.57
## - HDL.C..mM. 1 24.055 517.59 346.72
## - Palmitoylethanolamide 1 24.371 517.91 346.90
## - X3.Indolebutyric.acid 1 48.151 541.69 360.05
## - TG..mM. 1 61.797 555.33 367.34
##
## Step: AIC=332.78
## FBG..mM. ~ ALT..U.L. + AST..U.L. + Urea..mM. + Cre..uM. + UA..uM. +
## ALB..g.L. + TC..mM. + TG..mM. + HDL.C..mM. + LDL.C..mM. +
## ALP..U.L. + Υ.GT..U.L. + T.BIL..uM. + D.BIL..uM. + TBA..uM. +
## CHE..U.L. + WBC..10.9.L. + NEUT.... + LYMPH.... + EO.... +
## BASO.... + Phenylethylamine + Octadecanamide + Urocanic.acid +
## Imidazolepropionic.acid + Indole.3.carboxaldehyde + X3.Hydroxyanthranilic.acid +
## Dopamine + Oleamide + Oleoylethanolamide + Palmitic.amide +
## Palmitoylethanolamide + Stearoylethanolamide + Bilirubin...47 +
## Indole.3.acrylic.acid + Kynurenic.acid + Indole.3.propionic.acid +
## Indole.3.methyl.acetate + Dopa + Sphinganine + Sphinganine.1.phosphate +
## Sphingosine + X3.Indolebutyric.acid + Sphingosine.1.phosphate +
## X5.Methoxyindoleacetate + Phenylacetylglutamine.PAGln. +
## Pantothenol + Putrescine + Gamma.aminobutyric.acid + X5.Aminopentanoic.acid +
## N.Acetylcadaverine + Acetylcholine + Spermidine + N.acetyl.aspartic.acid +
## N8.Acetylspermidine + Spermine + Phenol + p.Cresol + X1.5.Anhydrosorbitol +
## Benzoic.acid + Phenylacetic.acid + X3.Hydroxybenzoic.acid +
## X4.Hydroxybenzoic.acid + Salicylic.acid + X3.Hydroxyphenylacetic.acid +
## Phenyllactate + X4.Hydroxyphenylpropionate + Bilirubin...82 +
## X3..3.Hydroxyphenyl..3.hydroxypropanoic.acid + X4.Hydroxyphenyllactate +
## p.Cresol.sulfate + X2.Hydroxy.Hippuric.Acid + X3.Hydroxyhippuric.acid +
## S.ganine.1.phosphate_b + S.gosine.1.phosphate_b + Cholesterol.sulfate +
## Xanthurenic.acid + Cinnamoylglycine + Indoxyl.sulfate + Ascorbic.acid +
## p.Cresol.glucuronide + Homovanillic.acid.sulfate + Iodide +
## Phenyl.sulfate + X4.Ethylphenyl.sulfate + X4.Hydroxybenzoic.acid.4.O.sulphate +
## X3.Hydroxypropionic.acid + Acetylglycine + Hippuric.acid
##
## Df Sum of Sq RSS AIC
## - LDL.C..mM. 1 0.006 493.54 330.78
## - X3.Hydroxyphenylacetic.acid 1 0.009 493.54 330.78
## - Urea..mM. 1 0.011 493.55 330.78
## - Dopamine 1 0.012 493.55 330.78
## - p.Cresol.glucuronide 1 0.017 493.55 330.79
## - BASO.... 1 0.024 493.56 330.79
## - S.gosine.1.phosphate_b 1 0.028 493.56 330.79
## - X4.Hydroxyphenylpropionate 1 0.041 493.58 330.80
## - Dopa 1 0.050 493.59 330.81
## - X4.Ethylphenyl.sulfate 1 0.055 493.59 330.81
## - Oleoylethanolamide 1 0.086 493.62 330.83
## - WBC..10.9.L. 1 0.089 493.62 330.83
## - Υ.GT..U.L. 1 0.098 493.63 330.84
## - Phenylacetic.acid 1 0.100 493.64 330.84
## - Putrescine 1 0.104 493.64 330.84
## - UA..uM. 1 0.104 493.64 330.84
## - TC..mM. 1 0.156 493.69 330.87
## - Sphingosine 1 0.160 493.70 330.87
## - X4.Hydroxybenzoic.acid 1 0.181 493.72 330.88
## - Palmitic.amide 1 0.194 493.73 330.89
## - Sphingosine.1.phosphate 1 0.231 493.77 330.91
## - p.Cresol.sulfate 1 0.250 493.79 330.93
## - CHE..U.L. 1 0.255 493.79 330.93
## - p.Cresol 1 0.305 493.84 330.96
## - Benzoic.acid 1 0.331 493.87 330.97
## - Stearoylethanolamide 1 0.334 493.87 330.98
## - Indole.3.propionic.acid 1 0.435 493.97 331.03
## - X5.Methoxyindoleacetate 1 0.610 494.15 331.14
## - X3.Hydroxybenzoic.acid 1 0.667 494.20 331.17
## - Spermidine 1 0.739 494.27 331.22
## - Spermine 1 0.753 494.29 331.22
## - X4.Hydroxyphenyllactate 1 0.825 494.36 331.27
## - Iodide 1 0.966 494.50 331.35
## - Salicylic.acid 1 1.030 494.57 331.39
## - Hippuric.acid 1 1.251 494.79 331.52
## - Cre..uM. 1 1.413 494.95 331.61
## - Phenol 1 1.607 495.14 331.73
## - X4.Hydroxybenzoic.acid.4.O.sulphate 1 1.772 495.31 331.83
## - Bilirubin...47 1 2.015 495.55 331.97
## - Urocanic.acid 1 2.052 495.59 331.99
## - ALP..U.L. 1 2.308 495.84 332.14
## - Indole.3.methyl.acetate 1 2.368 495.90 332.18
## - Acetylcholine 1 2.396 495.93 332.20
## - ALB..g.L. 1 2.418 495.95 332.21
## - N8.Acetylspermidine 1 2.456 495.99 332.23
## - Sphinganine.1.phosphate 1 2.533 496.07 332.28
## - N.Acetylcadaverine 1 2.950 496.49 332.52
## - Bilirubin...82 1 3.160 496.70 332.65
## - TBA..uM. 1 3.283 496.82 332.72
## - Homovanillic.acid.sulfate 1 3.323 496.86 332.74
## <none> 493.54 332.78
## - T.BIL..uM. 1 3.541 497.08 332.87
## - D.BIL..uM. 1 3.652 497.19 332.94
## - EO.... 1 3.979 497.51 333.13
## - Phenyllactate 1 4.091 497.63 333.20
## - Imidazolepropionic.acid 1 4.111 497.65 333.21
## - Cinnamoylglycine 1 4.408 497.94 333.38
## - X2.Hydroxy.Hippuric.Acid 1 4.483 498.02 333.43
## - Indoxyl.sulfate 1 4.820 498.36 333.62
## - Phenylacetylglutamine.PAGln. 1 5.118 498.65 333.80
## - N.acetyl.aspartic.acid 1 5.118 498.65 333.80
## - Phenylethylamine 1 5.641 499.18 334.11
## - Cholesterol.sulfate 1 5.848 499.38 334.23
## + Enterolactone 1 0.001 493.53 334.78
## + Biliverdin 1 0.000 493.54 334.78
## - X3.Hydroxyhippuric.acid 1 7.164 500.70 335.00
## - X3.Hydroxyanthranilic.acid 1 7.209 500.74 335.03
## - Xanthurenic.acid 1 7.440 500.98 335.16
## - Kynurenic.acid 1 7.781 501.32 335.36
## - Octadecanamide 1 7.893 501.43 335.43
## - Oleamide 1 7.901 501.44 335.43
## - Gamma.aminobutyric.acid 1 7.983 501.52 335.48
## - Indole.3.carboxaldehyde 1 8.260 501.80 335.64
## - S.ganine.1.phosphate_b 1 9.679 503.22 336.47
## - Sphinganine 1 10.282 503.82 336.82
## - Ascorbic.acid 1 10.359 503.89 336.86
## - LYMPH.... 1 10.642 504.18 337.03
## - NEUT.... 1 10.909 504.44 337.18
## - AST..U.L. 1 13.117 506.65 338.46
## - X5.Aminopentanoic.acid 1 14.154 507.69 339.06
## - Acetylglycine 1 14.392 507.93 339.20
## - Phenyl.sulfate 1 15.645 509.18 339.92
## - Pantothenol 1 16.850 510.39 340.61
## - ALT..U.L. 1 20.303 513.84 342.59
## - X3.Hydroxypropionic.acid 1 21.439 514.97 343.24
## - X3..3.Hydroxyphenyl..3.hydroxypropanoic.acid 1 22.477 516.01 343.83
## - X1.5.Anhydrosorbitol 1 23.331 516.87 344.31
## - Indole.3.acrylic.acid 1 23.846 517.38 344.60
## - HDL.C..mM. 1 24.120 517.66 344.76
## - Palmitoylethanolamide 1 24.369 517.91 344.90
## - X3.Indolebutyric.acid 1 48.150 541.69 358.05
## - TG..mM. 1 61.892 555.43 365.39
##
## Step: AIC=330.78
## FBG..mM. ~ ALT..U.L. + AST..U.L. + Urea..mM. + Cre..uM. + UA..uM. +
## ALB..g.L. + TC..mM. + TG..mM. + HDL.C..mM. + ALP..U.L. +
## Υ.GT..U.L. + T.BIL..uM. + D.BIL..uM. + TBA..uM. + CHE..U.L. +
## WBC..10.9.L. + NEUT.... + LYMPH.... + EO.... + BASO.... +
## Phenylethylamine + Octadecanamide + Urocanic.acid + Imidazolepropionic.acid +
## Indole.3.carboxaldehyde + X3.Hydroxyanthranilic.acid + Dopamine +
## Oleamide + Oleoylethanolamide + Palmitic.amide + Palmitoylethanolamide +
## Stearoylethanolamide + Bilirubin...47 + Indole.3.acrylic.acid +
## Kynurenic.acid + Indole.3.propionic.acid + Indole.3.methyl.acetate +
## Dopa + Sphinganine + Sphinganine.1.phosphate + Sphingosine +
## X3.Indolebutyric.acid + Sphingosine.1.phosphate + X5.Methoxyindoleacetate +
## Phenylacetylglutamine.PAGln. + Pantothenol + Putrescine +
## Gamma.aminobutyric.acid + X5.Aminopentanoic.acid + N.Acetylcadaverine +
## Acetylcholine + Spermidine + N.acetyl.aspartic.acid + N8.Acetylspermidine +
## Spermine + Phenol + p.Cresol + X1.5.Anhydrosorbitol + Benzoic.acid +
## Phenylacetic.acid + X3.Hydroxybenzoic.acid + X4.Hydroxybenzoic.acid +
## Salicylic.acid + X3.Hydroxyphenylacetic.acid + Phenyllactate +
## X4.Hydroxyphenylpropionate + Bilirubin...82 + X3..3.Hydroxyphenyl..3.hydroxypropanoic.acid +
## X4.Hydroxyphenyllactate + p.Cresol.sulfate + X2.Hydroxy.Hippuric.Acid +
## X3.Hydroxyhippuric.acid + S.ganine.1.phosphate_b + S.gosine.1.phosphate_b +
## Cholesterol.sulfate + Xanthurenic.acid + Cinnamoylglycine +
## Indoxyl.sulfate + Ascorbic.acid + p.Cresol.glucuronide +
## Homovanillic.acid.sulfate + Iodide + Phenyl.sulfate + X4.Ethylphenyl.sulfate +
## X4.Hydroxybenzoic.acid.4.O.sulphate + X3.Hydroxypropionic.acid +
## Acetylglycine + Hippuric.acid
##
## Df Sum of Sq RSS AIC
## - Urea..mM. 1 0.009 493.55 328.79
## - X3.Hydroxyphenylacetic.acid 1 0.009 493.55 328.79
## - Dopamine 1 0.011 493.55 328.79
## - p.Cresol.glucuronide 1 0.017 493.56 328.79
## - BASO.... 1 0.025 493.57 328.80
## - S.gosine.1.phosphate_b 1 0.029 493.57 328.80
## - X4.Hydroxyphenylpropionate 1 0.044 493.59 328.81
## - Dopa 1 0.049 493.59 328.81
## - X4.Ethylphenyl.sulfate 1 0.058 493.60 328.82
## - WBC..10.9.L. 1 0.088 493.63 328.83
## - Oleoylethanolamide 1 0.089 493.63 328.83
## - Υ.GT..U.L. 1 0.097 493.64 328.84
## - Phenylacetic.acid 1 0.102 493.64 328.84
## - Putrescine 1 0.102 493.64 328.84
## - UA..uM. 1 0.102 493.64 328.84
## - TC..mM. 1 0.152 493.69 328.87
## - Sphingosine 1 0.170 493.71 328.88
## - X4.Hydroxybenzoic.acid 1 0.183 493.72 328.89
## - Palmitic.amide 1 0.190 493.73 328.89
## - Sphingosine.1.phosphate 1 0.231 493.77 328.92
## - p.Cresol.sulfate 1 0.253 493.80 328.93
## - p.Cresol 1 0.303 493.84 328.96
## - CHE..U.L. 1 0.308 493.85 328.96
## - Stearoylethanolamide 1 0.335 493.88 328.98
## - Benzoic.acid 1 0.353 493.89 328.99
## - Indole.3.propionic.acid 1 0.431 493.97 329.04
## - X5.Methoxyindoleacetate 1 0.620 494.16 329.15
## - X3.Hydroxybenzoic.acid 1 0.668 494.21 329.18
## - Spermidine 1 0.755 494.30 329.23
## - Spermine 1 0.769 494.31 329.24
## - X4.Hydroxyphenyllactate 1 0.822 494.36 329.27
## - Iodide 1 0.982 494.52 329.36
## - Salicylic.acid 1 1.031 494.57 329.39
## - Hippuric.acid 1 1.246 494.79 329.52
## - Cre..uM. 1 1.418 494.96 329.62
## - Phenol 1 1.603 495.14 329.73
## - X4.Hydroxybenzoic.acid.4.O.sulphate 1 1.766 495.31 329.83
## - Bilirubin...47 1 2.016 495.56 329.97
## - Urocanic.acid 1 2.095 495.64 330.02
## - Indole.3.methyl.acetate 1 2.364 495.91 330.18
## - ALP..U.L. 1 2.394 495.94 330.20
## - ALB..g.L. 1 2.412 495.95 330.21
## - Acetylcholine 1 2.422 495.96 330.21
## - N8.Acetylspermidine 1 2.451 495.99 330.23
## - Sphinganine.1.phosphate 1 2.531 496.07 330.28
## - N.Acetylcadaverine 1 2.947 496.49 330.53
## - Bilirubin...82 1 3.190 496.73 330.67
## - TBA..uM. 1 3.312 496.85 330.74
## - Homovanillic.acid.sulfate 1 3.320 496.86 330.75
## <none> 493.54 330.78
## - EO.... 1 3.977 497.52 331.13
## - Imidazolepropionic.acid 1 4.105 497.65 331.21
## - Phenyllactate 1 4.168 497.71 331.24
## - Cinnamoylglycine 1 4.402 497.94 331.38
## - X2.Hydroxy.Hippuric.Acid 1 4.489 498.03 331.43
## - T.BIL..uM. 1 4.688 498.23 331.55
## - D.BIL..uM. 1 4.834 498.38 331.64
## - Indoxyl.sulfate 1 4.849 498.39 331.65
## - N.acetyl.aspartic.acid 1 5.112 498.65 331.80
## - Phenylacetylglutamine.PAGln. 1 5.154 498.70 331.82
## - Phenylethylamine 1 5.845 499.39 332.23
## - Cholesterol.sulfate 1 6.084 499.63 332.37
## + LDL.C..mM. 1 0.006 493.54 332.78
## + Enterolactone 1 0.001 493.54 332.78
## + Biliverdin 1 0.000 493.54 332.78
## - X3.Hydroxyanthranilic.acid 1 7.208 500.75 333.03
## - X3.Hydroxyhippuric.acid 1 7.211 500.75 333.03
## - Xanthurenic.acid 1 7.520 501.06 333.21
## - Kynurenic.acid 1 7.777 501.32 333.36
## - Oleamide 1 7.895 501.44 333.43
## - Octadecanamide 1 7.908 501.45 333.44
## - Gamma.aminobutyric.acid 1 8.001 501.54 333.49
## - Indole.3.carboxaldehyde 1 8.389 501.93 333.72
## - S.ganine.1.phosphate_b 1 9.673 503.22 334.47
## - Ascorbic.acid 1 10.400 503.94 334.89
## - Sphinganine 1 10.833 504.38 335.14
## - LYMPH.... 1 11.197 504.74 335.35
## - NEUT.... 1 11.568 505.11 335.57
## - AST..U.L. 1 13.129 506.67 336.47
## - X5.Aminopentanoic.acid 1 14.161 507.70 337.07
## - Acetylglycine 1 14.650 508.19 337.35
## - Phenyl.sulfate 1 15.650 509.19 337.93
## - Pantothenol 1 17.113 510.66 338.77
## - ALT..U.L. 1 20.697 514.24 340.82
## - X3.Hydroxypropionic.acid 1 21.567 515.11 341.31
## - X3..3.Hydroxyphenyl..3.hydroxypropanoic.acid 1 22.473 516.02 341.83
## - X1.5.Anhydrosorbitol 1 23.346 516.89 342.32
## - Indole.3.acrylic.acid 1 23.986 517.53 342.69
## - Palmitoylethanolamide 1 24.432 517.97 342.94
## - HDL.C..mM. 1 25.151 518.69 343.34
## - X3.Indolebutyric.acid 1 48.235 541.78 356.10
## - TG..mM. 1 69.103 562.65 367.18
##
## Step: AIC=328.79
## FBG..mM. ~ ALT..U.L. + AST..U.L. + Cre..uM. + UA..uM. + ALB..g.L. +
## TC..mM. + TG..mM. + HDL.C..mM. + ALP..U.L. + Υ.GT..U.L. +
## T.BIL..uM. + D.BIL..uM. + TBA..uM. + CHE..U.L. + WBC..10.9.L. +
## NEUT.... + LYMPH.... + EO.... + BASO.... + Phenylethylamine +
## Octadecanamide + Urocanic.acid + Imidazolepropionic.acid +
## Indole.3.carboxaldehyde + X3.Hydroxyanthranilic.acid + Dopamine +
## Oleamide + Oleoylethanolamide + Palmitic.amide + Palmitoylethanolamide +
## Stearoylethanolamide + Bilirubin...47 + Indole.3.acrylic.acid +
## Kynurenic.acid + Indole.3.propionic.acid + Indole.3.methyl.acetate +
## Dopa + Sphinganine + Sphinganine.1.phosphate + Sphingosine +
## X3.Indolebutyric.acid + Sphingosine.1.phosphate + X5.Methoxyindoleacetate +
## Phenylacetylglutamine.PAGln. + Pantothenol + Putrescine +
## Gamma.aminobutyric.acid + X5.Aminopentanoic.acid + N.Acetylcadaverine +
## Acetylcholine + Spermidine + N.acetyl.aspartic.acid + N8.Acetylspermidine +
## Spermine + Phenol + p.Cresol + X1.5.Anhydrosorbitol + Benzoic.acid +
## Phenylacetic.acid + X3.Hydroxybenzoic.acid + X4.Hydroxybenzoic.acid +
## Salicylic.acid + X3.Hydroxyphenylacetic.acid + Phenyllactate +
## X4.Hydroxyphenylpropionate + Bilirubin...82 + X3..3.Hydroxyphenyl..3.hydroxypropanoic.acid +
## X4.Hydroxyphenyllactate + p.Cresol.sulfate + X2.Hydroxy.Hippuric.Acid +
## X3.Hydroxyhippuric.acid + S.ganine.1.phosphate_b + S.gosine.1.phosphate_b +
## Cholesterol.sulfate + Xanthurenic.acid + Cinnamoylglycine +
## Indoxyl.sulfate + Ascorbic.acid + p.Cresol.glucuronide +
## Homovanillic.acid.sulfate + Iodide + Phenyl.sulfate + X4.Ethylphenyl.sulfate +
## X4.Hydroxybenzoic.acid.4.O.sulphate + X3.Hydroxypropionic.acid +
## Acetylglycine + Hippuric.acid
##
## Df Sum of Sq RSS AIC
## - X3.Hydroxyphenylacetic.acid 1 0.008 493.56 326.79
## - Dopamine 1 0.012 493.56 326.79
## - p.Cresol.glucuronide 1 0.020 493.57 326.80
## - BASO.... 1 0.022 493.57 326.80
## - S.gosine.1.phosphate_b 1 0.030 493.58 326.80
## - X4.Hydroxyphenylpropionate 1 0.041 493.59 326.81
## - Dopa 1 0.052 493.60 326.82
## - X4.Ethylphenyl.sulfate 1 0.059 493.61 326.82
## - WBC..10.9.L. 1 0.086 493.64 326.84
## - Oleoylethanolamide 1 0.087 493.64 326.84
## - Υ.GT..U.L. 1 0.100 493.65 326.85
## - Phenylacetic.acid 1 0.101 493.65 326.85
## - Putrescine 1 0.102 493.65 326.85
## - UA..uM. 1 0.104 493.66 326.85
## - Sphingosine 1 0.162 493.71 326.88
## - TC..mM. 1 0.162 493.71 326.88
## - X4.Hydroxybenzoic.acid 1 0.183 493.73 326.89
## - Palmitic.amide 1 0.196 493.75 326.90
## - Sphingosine.1.phosphate 1 0.230 493.78 326.92
## - p.Cresol.sulfate 1 0.256 493.81 326.94
## - p.Cresol 1 0.300 493.85 326.96
## - CHE..U.L. 1 0.307 493.86 326.97
## - Stearoylethanolamide 1 0.345 493.90 326.99
## - Benzoic.acid 1 0.357 493.91 327.00
## - Indole.3.propionic.acid 1 0.448 494.00 327.05
## - X5.Methoxyindoleacetate 1 0.616 494.17 327.15
## - X3.Hydroxybenzoic.acid 1 0.697 494.25 327.20
## - Spermidine 1 0.746 494.30 327.23
## - Spermine 1 0.804 494.36 327.26
## - X4.Hydroxyphenyllactate 1 0.814 494.37 327.27
## - Salicylic.acid 1 1.031 494.58 327.40
## - Iodide 1 1.032 494.58 327.40
## - Hippuric.acid 1 1.239 494.79 327.52
## - Cre..uM. 1 1.504 495.06 327.68
## - Phenol 1 1.601 495.15 327.74
## - X4.Hydroxybenzoic.acid.4.O.sulphate 1 1.780 495.33 327.84
## - Bilirubin...47 1 2.009 495.56 327.98
## - Urocanic.acid 1 2.091 495.64 328.03
## - Indole.3.methyl.acetate 1 2.408 495.96 328.21
## - Acetylcholine 1 2.413 495.96 328.22
## - ALB..g.L. 1 2.419 495.97 328.22
## - ALP..U.L. 1 2.423 495.97 328.22
## - N8.Acetylspermidine 1 2.444 496.00 328.23
## - Sphinganine.1.phosphate 1 2.531 496.08 328.28
## - N.Acetylcadaverine 1 3.011 496.56 328.57
## - Bilirubin...82 1 3.181 496.73 328.67
## - TBA..uM. 1 3.305 496.86 328.74
## - Homovanillic.acid.sulfate 1 3.311 496.86 328.75
## <none> 493.55 328.79
## - EO.... 1 4.018 497.57 329.16
## - Imidazolepropionic.acid 1 4.100 497.65 329.21
## - Phenyllactate 1 4.172 497.72 329.25
## - Cinnamoylglycine 1 4.404 497.96 329.39
## - X2.Hydroxy.Hippuric.Acid 1 4.480 498.03 329.43
## - T.BIL..uM. 1 4.694 498.25 329.56
## - D.BIL..uM. 1 4.834 498.39 329.64
## - Indoxyl.sulfate 1 4.866 498.42 329.66
## - N.acetyl.aspartic.acid 1 5.107 498.66 329.80
## - Phenylacetylglutamine.PAGln. 1 5.240 498.79 329.88
## - Phenylethylamine 1 5.843 499.39 330.23
## - Cholesterol.sulfate 1 6.091 499.64 330.38
## + Urea..mM. 1 0.009 493.54 330.78
## + LDL.C..mM. 1 0.005 493.55 330.78
## + Enterolactone 1 0.001 493.55 330.79
## + Biliverdin 1 0.001 493.55 330.79
## - X3.Hydroxyanthranilic.acid 1 7.204 500.76 331.03
## - X3.Hydroxyhippuric.acid 1 7.222 500.77 331.04
## - Xanthurenic.acid 1 7.526 501.08 331.22
## - Oleamide 1 7.891 501.44 331.43
## - Kynurenic.acid 1 7.923 501.47 331.45
## - Octadecanamide 1 7.926 501.48 331.45
## - Gamma.aminobutyric.acid 1 7.995 501.55 331.49
## - Indole.3.carboxaldehyde 1 8.387 501.94 331.72
## - S.ganine.1.phosphate_b 1 9.664 503.22 332.47
## - Ascorbic.acid 1 10.477 504.03 332.94
## - Sphinganine 1 11.043 504.59 333.27
## - LYMPH.... 1 11.228 504.78 333.38
## - NEUT.... 1 11.559 505.11 333.57
## - AST..U.L. 1 13.124 506.68 334.48
## - X5.Aminopentanoic.acid 1 14.193 507.74 335.09
## - Acetylglycine 1 14.655 508.21 335.36
## - Phenyl.sulfate 1 15.645 509.20 335.93
## - Pantothenol 1 17.104 510.66 336.77
## - ALT..U.L. 1 20.720 514.27 338.84
## - X3.Hydroxypropionic.acid 1 21.658 515.21 339.37
## - X3..3.Hydroxyphenyl..3.hydroxypropanoic.acid 1 22.789 516.34 340.01
## - X1.5.Anhydrosorbitol 1 23.474 517.03 340.40
## - Indole.3.acrylic.acid 1 24.004 517.56 340.70
## - Palmitoylethanolamide 1 24.423 517.97 340.94
## - HDL.C..mM. 1 25.600 519.15 341.60
## - X3.Indolebutyric.acid 1 48.238 541.79 354.11
## - TG..mM. 1 69.615 563.17 365.45
##
## Step: AIC=326.79
## FBG..mM. ~ ALT..U.L. + AST..U.L. + Cre..uM. + UA..uM. + ALB..g.L. +
## TC..mM. + TG..mM. + HDL.C..mM. + ALP..U.L. + Υ.GT..U.L. +
## T.BIL..uM. + D.BIL..uM. + TBA..uM. + CHE..U.L. + WBC..10.9.L. +
## NEUT.... + LYMPH.... + EO.... + BASO.... + Phenylethylamine +
## Octadecanamide + Urocanic.acid + Imidazolepropionic.acid +
## Indole.3.carboxaldehyde + X3.Hydroxyanthranilic.acid + Dopamine +
## Oleamide + Oleoylethanolamide + Palmitic.amide + Palmitoylethanolamide +
## Stearoylethanolamide + Bilirubin...47 + Indole.3.acrylic.acid +
## Kynurenic.acid + Indole.3.propionic.acid + Indole.3.methyl.acetate +
## Dopa + Sphinganine + Sphinganine.1.phosphate + Sphingosine +
## X3.Indolebutyric.acid + Sphingosine.1.phosphate + X5.Methoxyindoleacetate +
## Phenylacetylglutamine.PAGln. + Pantothenol + Putrescine +
## Gamma.aminobutyric.acid + X5.Aminopentanoic.acid + N.Acetylcadaverine +
## Acetylcholine + Spermidine + N.acetyl.aspartic.acid + N8.Acetylspermidine +
## Spermine + Phenol + p.Cresol + X1.5.Anhydrosorbitol + Benzoic.acid +
## Phenylacetic.acid + X3.Hydroxybenzoic.acid + X4.Hydroxybenzoic.acid +
## Salicylic.acid + Phenyllactate + X4.Hydroxyphenylpropionate +
## Bilirubin...82 + X3..3.Hydroxyphenyl..3.hydroxypropanoic.acid +
## X4.Hydroxyphenyllactate + p.Cresol.sulfate + X2.Hydroxy.Hippuric.Acid +
## X3.Hydroxyhippuric.acid + S.ganine.1.phosphate_b + S.gosine.1.phosphate_b +
## Cholesterol.sulfate + Xanthurenic.acid + Cinnamoylglycine +
## Indoxyl.sulfate + Ascorbic.acid + p.Cresol.glucuronide +
## Homovanillic.acid.sulfate + Iodide + Phenyl.sulfate + X4.Ethylphenyl.sulfate +
## X4.Hydroxybenzoic.acid.4.O.sulphate + X3.Hydroxypropionic.acid +
## Acetylglycine + Hippuric.acid
##
## Df Sum of Sq RSS AIC
## - Dopamine 1 0.012 493.57 324.80
## - p.Cresol.glucuronide 1 0.023 493.58 324.80
## - BASO.... 1 0.025 493.58 324.81
## - S.gosine.1.phosphate_b 1 0.030 493.59 324.81
## - X4.Hydroxyphenylpropionate 1 0.039 493.60 324.81
## - Dopa 1 0.054 493.61 324.82
## - X4.Ethylphenyl.sulfate 1 0.067 493.63 324.83
## - Oleoylethanolamide 1 0.086 493.65 324.84
## - WBC..10.9.L. 1 0.094 493.65 324.85
## - Putrescine 1 0.099 493.66 324.85
## - Υ.GT..U.L. 1 0.105 493.66 324.85
## - UA..uM. 1 0.108 493.67 324.85
## - Phenylacetic.acid 1 0.112 493.67 324.86
## - TC..mM. 1 0.157 493.72 324.88
## - Sphingosine 1 0.158 493.72 324.88
## - X4.Hydroxybenzoic.acid 1 0.183 493.74 324.90
## - Palmitic.amide 1 0.203 493.76 324.91
## - Sphingosine.1.phosphate 1 0.237 493.80 324.93
## - p.Cresol.sulfate 1 0.248 493.81 324.94
## - CHE..U.L. 1 0.317 493.88 324.98
## - p.Cresol 1 0.320 493.88 324.98
## - Stearoylethanolamide 1 0.342 493.90 324.99
## - Benzoic.acid 1 0.373 493.93 325.01
## - Indole.3.propionic.acid 1 0.480 494.04 325.08
## - X5.Methoxyindoleacetate 1 0.632 494.19 325.17
## - Spermidine 1 0.768 494.33 325.25
## - X3.Hydroxybenzoic.acid 1 0.795 494.35 325.26
## - Spermine 1 0.796 494.36 325.26
## - X4.Hydroxyphenyllactate 1 0.806 494.37 325.27
## - Salicylic.acid 1 1.031 494.59 325.40
## - Iodide 1 1.039 494.60 325.41
## - Hippuric.acid 1 1.249 494.81 325.53
## - Cre..uM. 1 1.496 495.06 325.68
## - Phenol 1 1.601 495.16 325.74
## - X4.Hydroxybenzoic.acid.4.O.sulphate 1 1.816 495.38 325.87
## - Bilirubin...47 1 2.001 495.56 325.98
## - Urocanic.acid 1 2.109 495.67 326.04
## - ALB..g.L. 1 2.414 495.97 326.22
## - Acetylcholine 1 2.418 495.98 326.22
## - N8.Acetylspermidine 1 2.439 496.00 326.24
## - ALP..U.L. 1 2.447 496.01 326.24
## - Indole.3.methyl.acetate 1 2.506 496.07 326.27
## - Sphinganine.1.phosphate 1 2.526 496.09 326.29
## - N.Acetylcadaverine 1 3.010 496.57 326.57
## - Bilirubin...82 1 3.193 496.75 326.68
## - Homovanillic.acid.sulfate 1 3.342 496.90 326.77
## - TBA..uM. 1 3.351 496.91 326.77
## <none> 493.56 326.79
## - Imidazolepropionic.acid 1 4.113 497.67 327.22
## - EO.... 1 4.157 497.72 327.25
## - Phenyllactate 1 4.165 497.72 327.25
## - Cinnamoylglycine 1 4.417 497.98 327.40
## - X2.Hydroxy.Hippuric.Acid 1 4.476 498.04 327.44
## - T.BIL..uM. 1 4.688 498.25 327.56
## - D.BIL..uM. 1 4.862 498.42 327.66
## - Indoxyl.sulfate 1 4.890 498.45 327.68
## - Phenylacetylglutamine.PAGln. 1 5.232 498.79 327.88
## - N.acetyl.aspartic.acid 1 5.269 498.83 327.90
## - Phenylethylamine 1 5.845 499.40 328.24
## - Cholesterol.sulfate 1 6.097 499.66 328.39
## + X3.Hydroxyphenylacetic.acid 1 0.008 493.55 328.79
## + Urea..mM. 1 0.008 493.55 328.79
## + LDL.C..mM. 1 0.006 493.55 328.79
## + Enterolactone 1 0.001 493.56 328.79
## + Biliverdin 1 0.001 493.56 328.79
## - X3.Hydroxyhippuric.acid 1 7.224 500.78 329.05
## - X3.Hydroxyanthranilic.acid 1 7.269 500.83 329.07
## - Xanthurenic.acid 1 7.519 501.08 329.22
## - Kynurenic.acid 1 7.962 501.52 329.48
## - Oleamide 1 8.002 501.56 329.50
## - Gamma.aminobutyric.acid 1 8.012 501.57 329.51
## - Octadecanamide 1 8.111 501.67 329.57
## - Indole.3.carboxaldehyde 1 8.404 501.96 329.74
## - S.ganine.1.phosphate_b 1 9.656 503.22 330.47
## - Ascorbic.acid 1 10.623 504.18 331.03
## - Sphinganine 1 11.035 504.59 331.27
## - LYMPH.... 1 11.546 505.11 331.57
## - NEUT.... 1 11.857 505.42 331.75
## - AST..U.L. 1 13.149 506.71 332.49
## - X5.Aminopentanoic.acid 1 14.211 507.77 333.11
## - Acetylglycine 1 14.772 508.33 333.43
## - Phenyl.sulfate 1 15.647 509.21 333.94
## - Pantothenol 1 17.187 510.75 334.82
## - ALT..U.L. 1 20.772 514.33 336.87
## - X3.Hydroxypropionic.acid 1 21.719 515.28 337.41
## - X3..3.Hydroxyphenyl..3.hydroxypropanoic.acid 1 22.822 516.38 338.04
## - X1.5.Anhydrosorbitol 1 23.744 517.30 338.56
## - Indole.3.acrylic.acid 1 24.116 517.68 338.77
## - Palmitoylethanolamide 1 24.445 518.00 338.95
## - HDL.C..mM. 1 25.926 519.49 339.79
## - X3.Indolebutyric.acid 1 48.346 541.91 352.17
## - TG..mM. 1 69.630 563.19 363.46
##
## Step: AIC=324.8
## FBG..mM. ~ ALT..U.L. + AST..U.L. + Cre..uM. + UA..uM. + ALB..g.L. +
## TC..mM. + TG..mM. + HDL.C..mM. + ALP..U.L. + Υ.GT..U.L. +
## T.BIL..uM. + D.BIL..uM. + TBA..uM. + CHE..U.L. + WBC..10.9.L. +
## NEUT.... + LYMPH.... + EO.... + BASO.... + Phenylethylamine +
## Octadecanamide + Urocanic.acid + Imidazolepropionic.acid +
## Indole.3.carboxaldehyde + X3.Hydroxyanthranilic.acid + Oleamide +
## Oleoylethanolamide + Palmitic.amide + Palmitoylethanolamide +
## Stearoylethanolamide + Bilirubin...47 + Indole.3.acrylic.acid +
## Kynurenic.acid + Indole.3.propionic.acid + Indole.3.methyl.acetate +
## Dopa + Sphinganine + Sphinganine.1.phosphate + Sphingosine +
## X3.Indolebutyric.acid + Sphingosine.1.phosphate + X5.Methoxyindoleacetate +
## Phenylacetylglutamine.PAGln. + Pantothenol + Putrescine +
## Gamma.aminobutyric.acid + X5.Aminopentanoic.acid + N.Acetylcadaverine +
## Acetylcholine + Spermidine + N.acetyl.aspartic.acid + N8.Acetylspermidine +
## Spermine + Phenol + p.Cresol + X1.5.Anhydrosorbitol + Benzoic.acid +
## Phenylacetic.acid + X3.Hydroxybenzoic.acid + X4.Hydroxybenzoic.acid +
## Salicylic.acid + Phenyllactate + X4.Hydroxyphenylpropionate +
## Bilirubin...82 + X3..3.Hydroxyphenyl..3.hydroxypropanoic.acid +
## X4.Hydroxyphenyllactate + p.Cresol.sulfate + X2.Hydroxy.Hippuric.Acid +
## X3.Hydroxyhippuric.acid + S.ganine.1.phosphate_b + S.gosine.1.phosphate_b +
## Cholesterol.sulfate + Xanthurenic.acid + Cinnamoylglycine +
## Indoxyl.sulfate + Ascorbic.acid + p.Cresol.glucuronide +
## Homovanillic.acid.sulfate + Iodide + Phenyl.sulfate + X4.Ethylphenyl.sulfate +
## X4.Hydroxybenzoic.acid.4.O.sulphate + X3.Hydroxypropionic.acid +
## Acetylglycine + Hippuric.acid
##
## Df Sum of Sq RSS AIC
## - p.Cresol.glucuronide 1 0.021 493.59 322.81
## - BASO.... 1 0.024 493.60 322.81
## - S.gosine.1.phosphate_b 1 0.038 493.61 322.82
## - X4.Hydroxyphenylpropionate 1 0.038 493.61 322.82
## - Dopa 1 0.059 493.63 322.83
## - X4.Ethylphenyl.sulfate 1 0.075 493.65 322.84
## - Oleoylethanolamide 1 0.080 493.65 322.85
## - WBC..10.9.L. 1 0.089 493.66 322.85
## - UA..uM. 1 0.103 493.67 322.86
## - Υ.GT..U.L. 1 0.103 493.67 322.86
## - Putrescine 1 0.108 493.68 322.86
## - Phenylacetic.acid 1 0.147 493.72 322.89
## - TC..mM. 1 0.149 493.72 322.89
## - Sphingosine 1 0.154 493.73 322.89
## - X4.Hydroxybenzoic.acid 1 0.177 493.75 322.90
## - Palmitic.amide 1 0.223 493.79 322.93
## - Sphingosine.1.phosphate 1 0.225 493.80 322.93
## - p.Cresol.sulfate 1 0.246 493.82 322.94
## - p.Cresol 1 0.321 493.89 322.99
## - CHE..U.L. 1 0.342 493.91 323.00
## - Stearoylethanolamide 1 0.357 493.93 323.01
## - Benzoic.acid 1 0.388 493.96 323.03
## - Indole.3.propionic.acid 1 0.487 494.06 323.09
## - X5.Methoxyindoleacetate 1 0.646 494.22 323.18
## - Spermidine 1 0.773 494.34 323.26
## - X3.Hydroxybenzoic.acid 1 0.784 494.36 323.26
## - Spermine 1 0.794 494.37 323.27
## - X4.Hydroxyphenyllactate 1 0.797 494.37 323.27
## - Salicylic.acid 1 1.020 494.59 323.40
## - Iodide 1 1.049 494.62 323.42
## - Hippuric.acid 1 1.273 494.84 323.55
## - Cre..uM. 1 1.523 495.09 323.70
## - Phenol 1 1.612 495.18 323.75
## - X4.Hydroxybenzoic.acid.4.O.sulphate 1 1.839 495.41 323.89
## - Bilirubin...47 1 1.998 495.57 323.98
## - Urocanic.acid 1 2.105 495.68 324.04
## - ALB..g.L. 1 2.403 495.97 324.22
## - ALP..U.L. 1 2.460 496.03 324.25
## - N8.Acetylspermidine 1 2.497 496.07 324.28
## - Indole.3.methyl.acetate 1 2.514 496.09 324.29
## - Sphinganine.1.phosphate 1 2.530 496.10 324.30
## - Acetylcholine 1 2.549 496.12 324.31
## - N.Acetylcadaverine 1 3.022 496.59 324.59
## - Bilirubin...82 1 3.209 496.78 324.70
## - Homovanillic.acid.sulfate 1 3.333 496.90 324.77
## - TBA..uM. 1 3.341 496.91 324.77
## <none> 493.57 324.80
## - Phenyllactate 1 4.182 497.75 325.27
## - EO.... 1 4.254 497.83 325.31
## - Cinnamoylglycine 1 4.440 498.01 325.42
## - X2.Hydroxy.Hippuric.Acid 1 4.471 498.04 325.44
## - T.BIL..uM. 1 4.680 498.25 325.56
## - D.BIL..uM. 1 4.866 498.44 325.67
## - Indoxyl.sulfate 1 4.885 498.46 325.68
## - Imidazolepropionic.acid 1 4.965 498.54 325.73
## - Phenylacetylglutamine.PAGln. 1 5.353 498.92 325.96
## - N.acetyl.aspartic.acid 1 5.455 499.03 326.02
## - Phenylethylamine 1 5.853 499.42 326.25
## - Cholesterol.sulfate 1 6.092 499.66 326.39
## + Dopamine 1 0.012 493.56 326.79
## + Urea..mM. 1 0.009 493.56 326.79
## + X3.Hydroxyphenylacetic.acid 1 0.008 493.56 326.79
## + LDL.C..mM. 1 0.005 493.57 326.80
## + Enterolactone 1 0.001 493.57 326.80
## + Biliverdin 1 0.000 493.57 326.80
## - X3.Hydroxyhippuric.acid 1 7.295 500.87 327.10
## - X3.Hydroxyanthranilic.acid 1 7.497 501.07 327.21
## - Xanthurenic.acid 1 7.508 501.08 327.22
## - Kynurenic.acid 1 7.951 501.52 327.48
## - Gamma.aminobutyric.acid 1 8.098 501.67 327.57
## - Octadecanamide 1 8.222 501.79 327.64
## - Oleamide 1 8.260 501.83 327.66
## - Indole.3.carboxaldehyde 1 8.422 501.99 327.76
## - S.ganine.1.phosphate_b 1 9.649 503.22 328.47
## - Ascorbic.acid 1 10.617 504.19 329.03
## - Sphinganine 1 11.088 504.66 329.31
## - LYMPH.... 1 11.731 505.30 329.68
## - NEUT.... 1 11.897 505.47 329.78
## - AST..U.L. 1 13.139 506.71 330.50
## - X5.Aminopentanoic.acid 1 14.202 507.77 331.11
## - Acetylglycine 1 14.766 508.34 331.44
## - Phenyl.sulfate 1 15.985 509.56 332.14
## - Pantothenol 1 17.422 510.99 332.96
## - ALT..U.L. 1 20.787 514.36 334.88
## - X3.Hydroxypropionic.acid 1 21.806 515.38 335.47
## - X3..3.Hydroxyphenyl..3.hydroxypropanoic.acid 1 22.834 516.41 336.05
## - X1.5.Anhydrosorbitol 1 23.847 517.42 336.62
## - Indole.3.acrylic.acid 1 24.313 517.88 336.89
## - Palmitoylethanolamide 1 24.808 518.38 337.17
## - HDL.C..mM. 1 25.914 519.49 337.79
## - X3.Indolebutyric.acid 1 48.356 541.93 350.18
## - TG..mM. 1 69.619 563.19 361.46
##
## Step: AIC=322.81
## FBG..mM. ~ ALT..U.L. + AST..U.L. + Cre..uM. + UA..uM. + ALB..g.L. +
## TC..mM. + TG..mM. + HDL.C..mM. + ALP..U.L. + Υ.GT..U.L. +
## T.BIL..uM. + D.BIL..uM. + TBA..uM. + CHE..U.L. + WBC..10.9.L. +
## NEUT.... + LYMPH.... + EO.... + BASO.... + Phenylethylamine +
## Octadecanamide + Urocanic.acid + Imidazolepropionic.acid +
## Indole.3.carboxaldehyde + X3.Hydroxyanthranilic.acid + Oleamide +
## Oleoylethanolamide + Palmitic.amide + Palmitoylethanolamide +
## Stearoylethanolamide + Bilirubin...47 + Indole.3.acrylic.acid +
## Kynurenic.acid + Indole.3.propionic.acid + Indole.3.methyl.acetate +
## Dopa + Sphinganine + Sphinganine.1.phosphate + Sphingosine +
## X3.Indolebutyric.acid + Sphingosine.1.phosphate + X5.Methoxyindoleacetate +
## Phenylacetylglutamine.PAGln. + Pantothenol + Putrescine +
## Gamma.aminobutyric.acid + X5.Aminopentanoic.acid + N.Acetylcadaverine +
## Acetylcholine + Spermidine + N.acetyl.aspartic.acid + N8.Acetylspermidine +
## Spermine + Phenol + p.Cresol + X1.5.Anhydrosorbitol + Benzoic.acid +
## Phenylacetic.acid + X3.Hydroxybenzoic.acid + X4.Hydroxybenzoic.acid +
## Salicylic.acid + Phenyllactate + X4.Hydroxyphenylpropionate +
## Bilirubin...82 + X3..3.Hydroxyphenyl..3.hydroxypropanoic.acid +
## X4.Hydroxyphenyllactate + p.Cresol.sulfate + X2.Hydroxy.Hippuric.Acid +
## X3.Hydroxyhippuric.acid + S.ganine.1.phosphate_b + S.gosine.1.phosphate_b +
## Cholesterol.sulfate + Xanthurenic.acid + Cinnamoylglycine +
## Indoxyl.sulfate + Ascorbic.acid + Homovanillic.acid.sulfate +
## Iodide + Phenyl.sulfate + X4.Ethylphenyl.sulfate + X4.Hydroxybenzoic.acid.4.O.sulphate +
## X3.Hydroxypropionic.acid + Acetylglycine + Hippuric.acid
##
## Df Sum of Sq RSS AIC
## - BASO.... 1 0.026 493.62 320.83
## - X4.Hydroxyphenylpropionate 1 0.038 493.63 320.83
## - S.gosine.1.phosphate_b 1 0.044 493.64 320.84
## - Dopa 1 0.070 493.66 320.85
## - Oleoylethanolamide 1 0.074 493.67 320.85
## - X4.Ethylphenyl.sulfate 1 0.081 493.67 320.86
## - WBC..10.9.L. 1 0.094 493.69 320.87
## - Υ.GT..U.L. 1 0.097 493.69 320.87
## - Putrescine 1 0.100 493.69 320.87
## - UA..uM. 1 0.106 493.70 320.87
## - TC..mM. 1 0.145 493.74 320.90
## - Phenylacetic.acid 1 0.164 493.76 320.91
## - Sphingosine 1 0.177 493.77 320.92
## - X4.Hydroxybenzoic.acid 1 0.178 493.77 320.92
## - Sphingosine.1.phosphate 1 0.229 493.82 320.95
## - Palmitic.amide 1 0.236 493.83 320.95
## - p.Cresol.sulfate 1 0.238 493.83 320.95
## - p.Cresol 1 0.304 493.90 320.99
## - CHE..U.L. 1 0.336 493.93 321.01
## - Stearoylethanolamide 1 0.361 493.95 321.02
## - Benzoic.acid 1 0.376 493.97 321.03
## - Indole.3.propionic.acid 1 0.493 494.09 321.10
## - X5.Methoxyindoleacetate 1 0.651 494.24 321.20
## - Spermidine 1 0.752 494.34 321.26
## - X3.Hydroxybenzoic.acid 1 0.763 494.36 321.26
## - X4.Hydroxyphenyllactate 1 0.780 494.37 321.27
## - Spermine 1 0.801 494.39 321.29
## - Salicylic.acid 1 1.026 494.62 321.42
## - Iodide 1 1.036 494.63 321.42
## - Hippuric.acid 1 1.294 494.89 321.58
## - Cre..uM. 1 1.530 495.12 321.72
## - Phenol 1 1.652 495.24 321.79
## - X4.Hydroxybenzoic.acid.4.O.sulphate 1 1.877 495.47 321.92
## - Bilirubin...47 1 2.008 495.60 322.00
## - Urocanic.acid 1 2.104 495.70 322.06
## - ALB..g.L. 1 2.387 495.98 322.22
## - ALP..U.L. 1 2.449 496.04 322.26
## - Indole.3.methyl.acetate 1 2.521 496.11 322.30
## - N8.Acetylspermidine 1 2.526 496.12 322.31
## - Sphinganine.1.phosphate 1 2.535 496.13 322.31
## - Acetylcholine 1 2.542 496.13 322.32
## - N.Acetylcadaverine 1 3.129 496.72 322.66
## - Bilirubin...82 1 3.240 496.83 322.73
## - Homovanillic.acid.sulfate 1 3.314 496.91 322.77
## - TBA..uM. 1 3.331 496.92 322.78
## <none> 493.59 322.81
## - Phenyllactate 1 4.164 497.76 323.27
## - EO.... 1 4.252 497.84 323.32
## - Cinnamoylglycine 1 4.430 498.02 323.43
## - X2.Hydroxy.Hippuric.Acid 1 4.515 498.11 323.48
## - T.BIL..uM. 1 4.717 498.31 323.60
## - D.BIL..uM. 1 4.867 498.46 323.68
## - Imidazolepropionic.acid 1 4.962 498.55 323.74
## - Indoxyl.sulfate 1 5.437 499.03 324.02
## - N.acetyl.aspartic.acid 1 5.510 499.10 324.06
## - Phenylethylamine 1 5.834 499.43 324.25
## - Cholesterol.sulfate 1 6.091 499.68 324.40
## - Phenylacetylglutamine.PAGln. 1 6.563 500.16 324.68
## + p.Cresol.glucuronide 1 0.021 493.57 324.80
## + Urea..mM. 1 0.012 493.58 324.80
## + Dopamine 1 0.010 493.58 324.80
## + X3.Hydroxyphenylacetic.acid 1 0.010 493.58 324.80
## + LDL.C..mM. 1 0.006 493.59 324.81
## + Biliverdin 1 0.000 493.59 324.81
## + Enterolactone 1 0.000 493.59 324.81
## - X3.Hydroxyhippuric.acid 1 7.276 500.87 325.10
## - Xanthurenic.acid 1 7.503 501.09 325.23
## - X3.Hydroxyanthranilic.acid 1 7.510 501.10 325.23
## - Kynurenic.acid 1 8.063 501.66 325.56
## - Octadecanamide 1 8.213 501.81 325.65
## - Gamma.aminobutyric.acid 1 8.214 501.81 325.65
## - Oleamide 1 8.256 501.85 325.67
## - Indole.3.carboxaldehyde 1 8.490 502.08 325.81
## - S.ganine.1.phosphate_b 1 9.735 503.33 326.53
## - Ascorbic.acid 1 10.638 504.23 327.06
## - Sphinganine 1 11.340 504.93 327.47
## - LYMPH.... 1 11.728 505.32 327.69
## - NEUT.... 1 11.919 505.51 327.80
## - AST..U.L. 1 13.129 506.72 328.50
## - X5.Aminopentanoic.acid 1 14.341 507.93 329.20
## - Acetylglycine 1 14.910 508.50 329.53
## - Phenyl.sulfate 1 16.337 509.93 330.35
## - Pantothenol 1 17.451 511.04 330.99
## - ALT..U.L. 1 20.829 514.42 332.92
## - X3.Hydroxypropionic.acid 1 22.692 516.28 333.98
## - X3..3.Hydroxyphenyl..3.hydroxypropanoic.acid 1 22.820 516.41 334.05
## - X1.5.Anhydrosorbitol 1 24.259 517.85 334.87
## - Indole.3.acrylic.acid 1 24.419 518.01 334.96
## - Palmitoylethanolamide 1 25.061 518.65 335.32
## - HDL.C..mM. 1 25.958 519.55 335.83
## - X3.Indolebutyric.acid 1 48.739 542.33 348.40
## - TG..mM. 1 69.626 563.22 359.47
##
## Step: AIC=320.83
## FBG..mM. ~ ALT..U.L. + AST..U.L. + Cre..uM. + UA..uM. + ALB..g.L. +
## TC..mM. + TG..mM. + HDL.C..mM. + ALP..U.L. + Υ.GT..U.L. +
## T.BIL..uM. + D.BIL..uM. + TBA..uM. + CHE..U.L. + WBC..10.9.L. +
## NEUT.... + LYMPH.... + EO.... + Phenylethylamine + Octadecanamide +
## Urocanic.acid + Imidazolepropionic.acid + Indole.3.carboxaldehyde +
## X3.Hydroxyanthranilic.acid + Oleamide + Oleoylethanolamide +
## Palmitic.amide + Palmitoylethanolamide + Stearoylethanolamide +
## Bilirubin...47 + Indole.3.acrylic.acid + Kynurenic.acid +
## Indole.3.propionic.acid + Indole.3.methyl.acetate + Dopa +
## Sphinganine + Sphinganine.1.phosphate + Sphingosine + X3.Indolebutyric.acid +
## Sphingosine.1.phosphate + X5.Methoxyindoleacetate + Phenylacetylglutamine.PAGln. +
## Pantothenol + Putrescine + Gamma.aminobutyric.acid + X5.Aminopentanoic.acid +
## N.Acetylcadaverine + Acetylcholine + Spermidine + N.acetyl.aspartic.acid +
## N8.Acetylspermidine + Spermine + Phenol + p.Cresol + X1.5.Anhydrosorbitol +
## Benzoic.acid + Phenylacetic.acid + X3.Hydroxybenzoic.acid +
## X4.Hydroxybenzoic.acid + Salicylic.acid + Phenyllactate +
## X4.Hydroxyphenylpropionate + Bilirubin...82 + X3..3.Hydroxyphenyl..3.hydroxypropanoic.acid +
## X4.Hydroxyphenyllactate + p.Cresol.sulfate + X2.Hydroxy.Hippuric.Acid +
## X3.Hydroxyhippuric.acid + S.ganine.1.phosphate_b + S.gosine.1.phosphate_b +
## Cholesterol.sulfate + Xanthurenic.acid + Cinnamoylglycine +
## Indoxyl.sulfate + Ascorbic.acid + Homovanillic.acid.sulfate +
## Iodide + Phenyl.sulfate + X4.Ethylphenyl.sulfate + X4.Hydroxybenzoic.acid.4.O.sulphate +
## X3.Hydroxypropionic.acid + Acetylglycine + Hippuric.acid
##
## Df Sum of Sq RSS AIC
## - S.gosine.1.phosphate_b 1 0.037 493.66 318.85
## - X4.Hydroxyphenylpropionate 1 0.041 493.66 318.85
## - Dopa 1 0.077 493.70 318.87
## - Oleoylethanolamide 1 0.081 493.70 318.87
## - X4.Ethylphenyl.sulfate 1 0.088 493.71 318.88
## - WBC..10.9.L. 1 0.098 493.72 318.88
## - Putrescine 1 0.102 493.72 318.89
## - Υ.GT..U.L. 1 0.102 493.72 318.89
## - UA..uM. 1 0.113 493.73 318.89
## - TC..mM. 1 0.138 493.76 318.91
## - Sphingosine 1 0.164 493.78 318.92
## - Phenylacetic.acid 1 0.166 493.78 318.92
## - X4.Hydroxybenzoic.acid 1 0.168 493.79 318.93
## - Sphingosine.1.phosphate 1 0.230 493.85 318.96
## - p.Cresol.sulfate 1 0.230 493.85 318.96
## - Palmitic.amide 1 0.259 493.88 318.98
## - p.Cresol 1 0.318 493.94 319.01
## - CHE..U.L. 1 0.336 493.95 319.02
## - Stearoylethanolamide 1 0.362 493.98 319.04
## - Benzoic.acid 1 0.369 493.99 319.04
## - Indole.3.propionic.acid 1 0.497 494.11 319.12
## - X5.Methoxyindoleacetate 1 0.649 494.27 319.21
## - X4.Hydroxyphenyllactate 1 0.757 494.37 319.27
## - Spermidine 1 0.760 494.38 319.28
## - X3.Hydroxybenzoic.acid 1 0.790 494.41 319.29
## - Spermine 1 0.798 494.42 319.30
## - Salicylic.acid 1 1.005 494.62 319.42
## - Iodide 1 1.053 494.67 319.45
## - Hippuric.acid 1 1.306 494.92 319.60
## - Cre..uM. 1 1.523 495.14 319.73
## - Phenol 1 1.629 495.25 319.79
## - X4.Hydroxybenzoic.acid.4.O.sulphate 1 1.895 495.51 319.95
## - Bilirubin...47 1 2.036 495.65 320.03
## - Urocanic.acid 1 2.081 495.70 320.06
## - ALB..g.L. 1 2.406 496.02 320.25
## - ALP..U.L. 1 2.453 496.07 320.28
## - N8.Acetylspermidine 1 2.514 496.13 320.31
## - Indole.3.methyl.acetate 1 2.528 496.15 320.32
## - Acetylcholine 1 2.537 496.16 320.33
## - Sphinganine.1.phosphate 1 2.578 496.20 320.35
## - N.Acetylcadaverine 1 3.106 496.72 320.66
## - Bilirubin...82 1 3.295 496.91 320.77
## - TBA..uM. 1 3.318 496.94 320.79
## - Homovanillic.acid.sulfate 1 3.330 496.95 320.80
## <none> 493.62 320.83
## - Phenyllactate 1 4.140 497.76 321.27
## - Cinnamoylglycine 1 4.435 498.05 321.45
## - X2.Hydroxy.Hippuric.Acid 1 4.490 498.11 321.48
## - T.BIL..uM. 1 4.745 498.36 321.63
## - EO.... 1 4.804 498.42 321.66
## - D.BIL..uM. 1 4.896 498.51 321.72
## - Imidazolepropionic.acid 1 4.962 498.58 321.76
## - Indoxyl.sulfate 1 5.462 499.08 322.05
## - N.acetyl.aspartic.acid 1 5.484 499.10 322.06
## - Phenylethylamine 1 5.813 499.43 322.26
## - Cholesterol.sulfate 1 6.066 499.68 322.40
## + BASO.... 1 0.026 493.59 322.81
## + p.Cresol.glucuronide 1 0.022 493.60 322.81
## + X3.Hydroxyphenylacetic.acid 1 0.013 493.61 322.82
## + Dopamine 1 0.009 493.61 322.82
## + Urea..mM. 1 0.009 493.61 322.82
## + LDL.C..mM. 1 0.007 493.61 322.82
## - Phenylacetylglutamine.PAGln. 1 6.779 500.40 322.82
## + Enterolactone 1 0.000 493.62 322.83
## + Biliverdin 1 0.000 493.62 322.83
## - X3.Hydroxyhippuric.acid 1 7.319 500.94 323.14
## - X3.Hydroxyanthranilic.acid 1 7.486 501.10 323.24
## - Xanthurenic.acid 1 7.575 501.19 323.29
## - Kynurenic.acid 1 8.140 501.76 323.62
## - Gamma.aminobutyric.acid 1 8.210 501.83 323.66
## - Oleamide 1 8.234 501.85 323.67
## - Octadecanamide 1 8.324 501.94 323.73
## - Indole.3.carboxaldehyde 1 8.476 502.09 323.81
## - S.ganine.1.phosphate_b 1 9.747 503.37 324.55
## - Ascorbic.acid 1 10.671 504.29 325.09
## - Sphinganine 1 11.324 504.94 325.47
## - LYMPH.... 1 11.911 505.53 325.81
## - NEUT.... 1 12.140 505.76 325.94
## - AST..U.L. 1 13.107 506.72 326.50
## - X5.Aminopentanoic.acid 1 14.323 507.94 327.21
## - Acetylglycine 1 15.313 508.93 327.78
## - Phenyl.sulfate 1 16.361 509.98 328.38
## - Pantothenol 1 17.442 511.06 329.00
## - ALT..U.L. 1 20.809 514.43 330.92
## - X3.Hydroxypropionic.acid 1 22.782 516.40 332.05
## - X3..3.Hydroxyphenyl..3.hydroxypropanoic.acid 1 23.147 516.76 332.25
## - X1.5.Anhydrosorbitol 1 24.267 517.88 332.89
## - Indole.3.acrylic.acid 1 24.531 518.15 333.04
## - Palmitoylethanolamide 1 25.038 518.66 333.32
## - HDL.C..mM. 1 25.956 519.57 333.84
## - X3.Indolebutyric.acid 1 49.649 543.27 346.91
## - TG..mM. 1 69.606 563.22 357.48
##
## Step: AIC=318.85
## FBG..mM. ~ ALT..U.L. + AST..U.L. + Cre..uM. + UA..uM. + ALB..g.L. +
## TC..mM. + TG..mM. + HDL.C..mM. + ALP..U.L. + Υ.GT..U.L. +
## T.BIL..uM. + D.BIL..uM. + TBA..uM. + CHE..U.L. + WBC..10.9.L. +
## NEUT.... + LYMPH.... + EO.... + Phenylethylamine + Octadecanamide +
## Urocanic.acid + Imidazolepropionic.acid + Indole.3.carboxaldehyde +
## X3.Hydroxyanthranilic.acid + Oleamide + Oleoylethanolamide +
## Palmitic.amide + Palmitoylethanolamide + Stearoylethanolamide +
## Bilirubin...47 + Indole.3.acrylic.acid + Kynurenic.acid +
## Indole.3.propionic.acid + Indole.3.methyl.acetate + Dopa +
## Sphinganine + Sphinganine.1.phosphate + Sphingosine + X3.Indolebutyric.acid +
## Sphingosine.1.phosphate + X5.Methoxyindoleacetate + Phenylacetylglutamine.PAGln. +
## Pantothenol + Putrescine + Gamma.aminobutyric.acid + X5.Aminopentanoic.acid +
## N.Acetylcadaverine + Acetylcholine + Spermidine + N.acetyl.aspartic.acid +
## N8.Acetylspermidine + Spermine + Phenol + p.Cresol + X1.5.Anhydrosorbitol +
## Benzoic.acid + Phenylacetic.acid + X3.Hydroxybenzoic.acid +
## X4.Hydroxybenzoic.acid + Salicylic.acid + Phenyllactate +
## X4.Hydroxyphenylpropionate + Bilirubin...82 + X3..3.Hydroxyphenyl..3.hydroxypropanoic.acid +
## X4.Hydroxyphenyllactate + p.Cresol.sulfate + X2.Hydroxy.Hippuric.Acid +
## X3.Hydroxyhippuric.acid + S.ganine.1.phosphate_b + Cholesterol.sulfate +
## Xanthurenic.acid + Cinnamoylglycine + Indoxyl.sulfate + Ascorbic.acid +
## Homovanillic.acid.sulfate + Iodide + Phenyl.sulfate + X4.Ethylphenyl.sulfate +
## X4.Hydroxybenzoic.acid.4.O.sulphate + X3.Hydroxypropionic.acid +
## Acetylglycine + Hippuric.acid
##
## Df Sum of Sq RSS AIC
## - X4.Hydroxyphenylpropionate 1 0.054 493.71 316.88
## - Dopa 1 0.074 493.73 316.89
## - X4.Ethylphenyl.sulfate 1 0.084 493.74 316.90
## - Oleoylethanolamide 1 0.084 493.74 316.90
## - Υ.GT..U.L. 1 0.094 493.75 316.90
## - WBC..10.9.L. 1 0.107 493.76 316.91
## - UA..uM. 1 0.114 493.77 316.92
## - TC..mM. 1 0.138 493.79 316.93
## - Sphingosine 1 0.152 493.81 316.94
## - Phenylacetic.acid 1 0.155 493.81 316.94
## - Putrescine 1 0.183 493.84 316.96
## - X4.Hydroxybenzoic.acid 1 0.187 493.84 316.96
## - p.Cresol.sulfate 1 0.237 493.89 316.99
## - Palmitic.amide 1 0.247 493.90 316.99
## - p.Cresol 1 0.312 493.97 317.03
## - CHE..U.L. 1 0.338 493.99 317.05
## - Stearoylethanolamide 1 0.346 494.00 317.05
## - Benzoic.acid 1 0.352 494.01 317.06
## - Sphingosine.1.phosphate 1 0.451 494.11 317.12
## - Indole.3.propionic.acid 1 0.485 494.14 317.14
## - X5.Methoxyindoleacetate 1 0.653 494.31 317.24
## - Spermidine 1 0.734 494.39 317.28
## - X4.Hydroxyphenyllactate 1 0.754 494.41 317.29
## - X3.Hydroxybenzoic.acid 1 0.799 494.45 317.32
## - Spermine 1 0.814 494.47 317.33
## - Iodide 1 1.060 494.72 317.48
## - Salicylic.acid 1 1.066 494.72 317.48
## - Hippuric.acid 1 1.321 494.98 317.63
## - Cre..uM. 1 1.486 495.14 317.73
## - Phenol 1 1.636 495.29 317.82
## - X4.Hydroxybenzoic.acid.4.O.sulphate 1 1.872 495.53 317.96
## - Urocanic.acid 1 2.101 495.76 318.09
## - Bilirubin...47 1 2.298 495.95 318.21
## - ALB..g.L. 1 2.401 496.06 318.27
## - ALP..U.L. 1 2.435 496.09 318.29
## - Indole.3.methyl.acetate 1 2.511 496.17 318.33
## - N8.Acetylspermidine 1 2.546 496.20 318.36
## - Acetylcholine 1 2.613 496.27 318.39
## - Sphinganine.1.phosphate 1 2.910 496.56 318.57
## - N.Acetylcadaverine 1 3.145 496.80 318.71
## - Homovanillic.acid.sulfate 1 3.303 496.96 318.80
## - TBA..uM. 1 3.354 497.01 318.83
## <none> 493.66 318.85
## - Bilirubin...82 1 3.413 497.07 318.87
## - Phenyllactate 1 4.107 497.76 319.28
## - X2.Hydroxy.Hippuric.Acid 1 4.591 498.25 319.56
## - Cinnamoylglycine 1 4.697 498.35 319.62
## - T.BIL..uM. 1 4.709 498.36 319.63
## - EO.... 1 4.841 498.50 319.71
## - D.BIL..uM. 1 4.879 498.53 319.73
## - Imidazolepropionic.acid 1 4.936 498.59 319.76
## - N.acetyl.aspartic.acid 1 5.465 499.12 320.07
## - Indoxyl.sulfate 1 5.590 499.25 320.15
## - Phenylethylamine 1 6.041 499.70 320.41
## - Cholesterol.sulfate 1 6.095 499.75 320.44
## + S.gosine.1.phosphate_b 1 0.037 493.62 320.83
## + p.Cresol.glucuronide 1 0.028 493.63 320.83
## + BASO.... 1 0.019 493.64 320.84
## + Dopamine 1 0.016 493.64 320.84
## + X3.Hydroxyphenylacetic.acid 1 0.012 493.64 320.84
## + Urea..mM. 1 0.010 493.65 320.84
## + LDL.C..mM. 1 0.007 493.65 320.84
## + Enterolactone 1 0.000 493.66 320.85
## + Biliverdin 1 0.000 493.66 320.85
## - Phenylacetylglutamine.PAGln. 1 6.829 500.48 320.87
## - X3.Hydroxyhippuric.acid 1 7.329 500.98 321.17
## - X3.Hydroxyanthranilic.acid 1 7.669 501.32 321.36
## - Xanthurenic.acid 1 7.738 501.39 321.41
## - Gamma.aminobutyric.acid 1 8.317 501.97 321.74
## - Kynurenic.acid 1 8.321 501.98 321.75
## - Oleamide 1 8.506 502.16 321.85
## - Octadecanamide 1 8.743 502.40 321.99
## - Indole.3.carboxaldehyde 1 8.856 502.51 322.06
## - S.ganine.1.phosphate_b 1 9.827 503.48 322.62
## - Ascorbic.acid 1 10.946 504.60 323.27
## - Sphinganine 1 11.346 505.00 323.51
## - LYMPH.... 1 12.042 505.70 323.91
## - NEUT.... 1 12.232 505.89 324.02
## - AST..U.L. 1 13.253 506.91 324.61
## - X5.Aminopentanoic.acid 1 14.293 507.95 325.21
## - Acetylglycine 1 15.927 509.58 326.15
## - Phenyl.sulfate 1 16.513 510.17 326.49
## - Pantothenol 1 17.578 511.23 327.10
## - ALT..U.L. 1 20.903 514.56 329.00
## - X3.Hydroxypropionic.acid 1 22.845 516.50 330.10
## - X3..3.Hydroxyphenyl..3.hydroxypropanoic.acid 1 23.117 516.77 330.26
## - X1.5.Anhydrosorbitol 1 24.975 518.63 331.31
## - Palmitoylethanolamide 1 25.118 518.77 331.39
## - Indole.3.acrylic.acid 1 25.707 519.36 331.72
## - HDL.C..mM. 1 26.341 520.00 332.08
## - X3.Indolebutyric.acid 1 53.276 546.93 346.88
## - TG..mM. 1 70.009 563.66 355.71
##
## Step: AIC=316.88
## FBG..mM. ~ ALT..U.L. + AST..U.L. + Cre..uM. + UA..uM. + ALB..g.L. +
## TC..mM. + TG..mM. + HDL.C..mM. + ALP..U.L. + Υ.GT..U.L. +
## T.BIL..uM. + D.BIL..uM. + TBA..uM. + CHE..U.L. + WBC..10.9.L. +
## NEUT.... + LYMPH.... + EO.... + Phenylethylamine + Octadecanamide +
## Urocanic.acid + Imidazolepropionic.acid + Indole.3.carboxaldehyde +
## X3.Hydroxyanthranilic.acid + Oleamide + Oleoylethanolamide +
## Palmitic.amide + Palmitoylethanolamide + Stearoylethanolamide +
## Bilirubin...47 + Indole.3.acrylic.acid + Kynurenic.acid +
## Indole.3.propionic.acid + Indole.3.methyl.acetate + Dopa +
## Sphinganine + Sphinganine.1.phosphate + Sphingosine + X3.Indolebutyric.acid +
## Sphingosine.1.phosphate + X5.Methoxyindoleacetate + Phenylacetylglutamine.PAGln. +
## Pantothenol + Putrescine + Gamma.aminobutyric.acid + X5.Aminopentanoic.acid +
## N.Acetylcadaverine + Acetylcholine + Spermidine + N.acetyl.aspartic.acid +
## N8.Acetylspermidine + Spermine + Phenol + p.Cresol + X1.5.Anhydrosorbitol +
## Benzoic.acid + Phenylacetic.acid + X3.Hydroxybenzoic.acid +
## X4.Hydroxybenzoic.acid + Salicylic.acid + Phenyllactate +
## Bilirubin...82 + X3..3.Hydroxyphenyl..3.hydroxypropanoic.acid +
## X4.Hydroxyphenyllactate + p.Cresol.sulfate + X2.Hydroxy.Hippuric.Acid +
## X3.Hydroxyhippuric.acid + S.ganine.1.phosphate_b + Cholesterol.sulfate +
## Xanthurenic.acid + Cinnamoylglycine + Indoxyl.sulfate + Ascorbic.acid +
## Homovanillic.acid.sulfate + Iodide + Phenyl.sulfate + X4.Ethylphenyl.sulfate +
## X4.Hydroxybenzoic.acid.4.O.sulphate + X3.Hydroxypropionic.acid +
## Acetylglycine + Hippuric.acid
##
## Df Sum of Sq RSS AIC
## - X4.Ethylphenyl.sulfate 1 0.090 493.80 314.93
## - Υ.GT..U.L. 1 0.101 493.81 314.94
## - UA..uM. 1 0.101 493.81 314.94
## - Oleoylethanolamide 1 0.102 493.81 314.94
## - Dopa 1 0.106 493.82 314.94
## - WBC..10.9.L. 1 0.107 493.82 314.94
## - Sphingosine 1 0.127 493.84 314.96
## - TC..mM. 1 0.132 493.84 314.96
## - Phenylacetic.acid 1 0.155 493.86 314.97
## - Putrescine 1 0.166 493.88 314.98
## - X4.Hydroxybenzoic.acid 1 0.178 493.89 314.99
## - p.Cresol.sulfate 1 0.209 493.92 315.00
## - Palmitic.amide 1 0.265 493.97 315.04
## - Stearoylethanolamide 1 0.331 494.04 315.08
## - CHE..U.L. 1 0.339 494.05 315.08
## - Benzoic.acid 1 0.345 494.05 315.08
## - p.Cresol 1 0.345 494.05 315.08
## - Sphingosine.1.phosphate 1 0.442 494.15 315.14
## - Indole.3.propionic.acid 1 0.617 494.33 315.25
## - X5.Methoxyindoleacetate 1 0.657 494.37 315.27
## - Spermidine 1 0.747 494.46 315.32
## - X3.Hydroxybenzoic.acid 1 0.772 494.48 315.34
## - X4.Hydroxyphenyllactate 1 0.781 494.49 315.34
## - Spermine 1 0.799 494.51 315.35
## - Salicylic.acid 1 1.042 494.75 315.50
## - Iodide 1 1.084 494.79 315.52
## - Cre..uM. 1 1.453 495.16 315.74
## - Hippuric.acid 1 1.502 495.21 315.77
## - Phenol 1 1.596 495.31 315.83
## - X4.Hydroxybenzoic.acid.4.O.sulphate 1 1.953 495.66 316.04
## - Urocanic.acid 1 2.113 495.82 316.13
## - Bilirubin...47 1 2.323 496.03 316.26
## - ALB..g.L. 1 2.379 496.09 316.29
## - ALP..U.L. 1 2.439 496.15 316.32
## - N8.Acetylspermidine 1 2.562 496.27 316.40
## - Acetylcholine 1 2.568 496.28 316.40
## - Indole.3.methyl.acetate 1 2.823 496.53 316.55
## - Sphinganine.1.phosphate 1 2.890 496.60 316.59
## - N.Acetylcadaverine 1 3.092 496.80 316.71
## - Homovanillic.acid.sulfate 1 3.288 497.00 316.82
## <none> 493.71 316.88
## - TBA..uM. 1 3.452 497.16 316.92
## - Bilirubin...82 1 3.499 497.21 316.95
## - Phenyllactate 1 4.110 497.82 317.31
## - X2.Hydroxy.Hippuric.Acid 1 4.556 498.27 317.57
## - T.BIL..uM. 1 4.705 498.41 317.66
## - Cinnamoylglycine 1 4.727 498.44 317.67
## - D.BIL..uM. 1 4.852 498.56 317.75
## - EO.... 1 4.918 498.63 317.78
## - Imidazolepropionic.acid 1 4.974 498.68 317.82
## - N.acetyl.aspartic.acid 1 5.413 499.12 318.08
## - Indoxyl.sulfate 1 5.538 499.25 318.15
## - Phenylethylamine 1 5.987 499.70 318.41
## - Cholesterol.sulfate 1 6.059 499.77 318.45
## + X4.Hydroxyphenylpropionate 1 0.054 493.66 318.85
## + S.gosine.1.phosphate_b 1 0.050 493.66 318.85
## + p.Cresol.glucuronide 1 0.029 493.68 318.86
## + BASO.... 1 0.021 493.69 318.87
## + Dopamine 1 0.017 493.69 318.87
## + LDL.C..mM. 1 0.010 493.70 318.87
## - Phenylacetylglutamine.PAGln. 1 6.776 500.49 318.87
## + X3.Hydroxyphenylacetic.acid 1 0.009 493.70 318.87
## + Urea..mM. 1 0.008 493.70 318.88
## + Biliverdin 1 0.000 493.71 318.88
## + Enterolactone 1 0.000 493.71 318.88
## - X3.Hydroxyhippuric.acid 1 7.504 501.21 319.30
## - X3.Hydroxyanthranilic.acid 1 7.678 501.39 319.40
## - Xanthurenic.acid 1 7.864 501.57 319.51
## - Gamma.aminobutyric.acid 1 8.267 501.98 319.75
## - Kynurenic.acid 1 8.277 501.99 319.75
## - Oleamide 1 8.476 502.19 319.87
## - Octadecanamide 1 8.700 502.41 320.00
## - Indole.3.carboxaldehyde 1 8.812 502.52 320.06
## - S.ganine.1.phosphate_b 1 9.801 503.51 320.64
## - Ascorbic.acid 1 11.019 504.73 321.35
## - Sphinganine 1 11.308 505.02 321.52
## - LYMPH.... 1 12.027 505.74 321.93
## - NEUT.... 1 12.257 505.97 322.07
## - AST..U.L. 1 13.300 507.01 322.67
## - X5.Aminopentanoic.acid 1 14.252 507.96 323.22
## - Acetylglycine 1 16.418 510.13 324.47
## - Phenyl.sulfate 1 16.477 510.19 324.50
## - Pantothenol 1 17.645 511.35 325.17
## - ALT..U.L. 1 20.866 514.58 327.01
## - X3.Hydroxypropionic.acid 1 23.352 517.06 328.42
## - X3..3.Hydroxyphenyl..3.hydroxypropanoic.acid 1 23.440 517.15 328.47
## - Palmitoylethanolamide 1 25.070 518.78 329.39
## - X1.5.Anhydrosorbitol 1 25.214 518.92 329.47
## - HDL.C..mM. 1 26.328 520.04 330.10
## - Indole.3.acrylic.acid 1 38.218 531.93 336.73
## - X3.Indolebutyric.acid 1 54.001 547.71 345.29
## - TG..mM. 1 69.957 563.67 353.71
##
## Step: AIC=314.93
## FBG..mM. ~ ALT..U.L. + AST..U.L. + Cre..uM. + UA..uM. + ALB..g.L. +
## TC..mM. + TG..mM. + HDL.C..mM. + ALP..U.L. + Υ.GT..U.L. +
## T.BIL..uM. + D.BIL..uM. + TBA..uM. + CHE..U.L. + WBC..10.9.L. +
## NEUT.... + LYMPH.... + EO.... + Phenylethylamine + Octadecanamide +
## Urocanic.acid + Imidazolepropionic.acid + Indole.3.carboxaldehyde +
## X3.Hydroxyanthranilic.acid + Oleamide + Oleoylethanolamide +
## Palmitic.amide + Palmitoylethanolamide + Stearoylethanolamide +
## Bilirubin...47 + Indole.3.acrylic.acid + Kynurenic.acid +
## Indole.3.propionic.acid + Indole.3.methyl.acetate + Dopa +
## Sphinganine + Sphinganine.1.phosphate + Sphingosine + X3.Indolebutyric.acid +
## Sphingosine.1.phosphate + X5.Methoxyindoleacetate + Phenylacetylglutamine.PAGln. +
## Pantothenol + Putrescine + Gamma.aminobutyric.acid + X5.Aminopentanoic.acid +
## N.Acetylcadaverine + Acetylcholine + Spermidine + N.acetyl.aspartic.acid +
## N8.Acetylspermidine + Spermine + Phenol + p.Cresol + X1.5.Anhydrosorbitol +
## Benzoic.acid + Phenylacetic.acid + X3.Hydroxybenzoic.acid +
## X4.Hydroxybenzoic.acid + Salicylic.acid + Phenyllactate +
## Bilirubin...82 + X3..3.Hydroxyphenyl..3.hydroxypropanoic.acid +
## X4.Hydroxyphenyllactate + p.Cresol.sulfate + X2.Hydroxy.Hippuric.Acid +
## X3.Hydroxyhippuric.acid + S.ganine.1.phosphate_b + Cholesterol.sulfate +
## Xanthurenic.acid + Cinnamoylglycine + Indoxyl.sulfate + Ascorbic.acid +
## Homovanillic.acid.sulfate + Iodide + Phenyl.sulfate + X4.Hydroxybenzoic.acid.4.O.sulphate +
## X3.Hydroxypropionic.acid + Acetylglycine + Hippuric.acid
##
## Df Sum of Sq RSS AIC
## - Oleoylethanolamide 1 0.066 493.87 312.97
## - WBC..10.9.L. 1 0.078 493.88 312.98
## - UA..uM. 1 0.092 493.89 312.99
## - Υ.GT..U.L. 1 0.098 493.90 312.99
## - Dopa 1 0.113 493.91 313.00
## - Sphingosine 1 0.140 493.94 313.02
## - TC..mM. 1 0.145 493.94 313.02
## - Phenylacetic.acid 1 0.153 493.95 313.02
## - Putrescine 1 0.174 493.97 313.04
## - X4.Hydroxybenzoic.acid 1 0.203 494.00 313.05
## - Palmitic.amide 1 0.260 494.06 313.09
## - p.Cresol.sulfate 1 0.270 494.07 313.09
## - Benzoic.acid 1 0.295 494.09 313.11
## - p.Cresol 1 0.299 494.10 313.11
## - CHE..U.L. 1 0.339 494.14 313.13
## - Stearoylethanolamide 1 0.376 494.18 313.16
## - Sphingosine.1.phosphate 1 0.480 494.28 313.22
## - Indole.3.propionic.acid 1 0.621 494.42 313.30
## - X5.Methoxyindoleacetate 1 0.720 494.52 313.36
## - Spermidine 1 0.759 494.56 313.38
## - X3.Hydroxybenzoic.acid 1 0.798 494.60 313.41
## - Spermine 1 0.802 494.60 313.41
## - X4.Hydroxyphenyllactate 1 0.867 494.67 313.45
## - Iodide 1 1.012 494.81 313.53
## - Salicylic.acid 1 1.109 494.91 313.59
## - Cre..uM. 1 1.462 495.26 313.80
## - Hippuric.acid 1 1.533 495.33 313.84
## - Phenol 1 1.586 495.39 313.87
## - X4.Hydroxybenzoic.acid.4.O.sulphate 1 2.043 495.84 314.14
## - Urocanic.acid 1 2.053 495.85 314.15
## - Bilirubin...47 1 2.281 496.08 314.28
## - ALB..g.L. 1 2.298 496.10 314.29
## - ALP..U.L. 1 2.572 496.37 314.46
## - Acetylcholine 1 2.578 496.38 314.46
## - N8.Acetylspermidine 1 2.604 496.40 314.47
## - Indole.3.methyl.acetate 1 2.837 496.64 314.61
## - Sphinganine.1.phosphate 1 2.853 496.65 314.62
## - N.Acetylcadaverine 1 3.071 496.87 314.75
## - TBA..uM. 1 3.363 497.16 314.92
## <none> 493.80 314.93
## - Homovanillic.acid.sulfate 1 3.442 497.24 314.97
## - Bilirubin...82 1 3.496 497.30 315.00
## - Phenyllactate 1 4.491 498.29 315.59
## - X2.Hydroxy.Hippuric.Acid 1 4.630 498.43 315.67
## - Cinnamoylglycine 1 4.641 498.44 315.67
## - T.BIL..uM. 1 4.682 498.48 315.70
## - D.BIL..uM. 1 4.812 498.61 315.77
## - EO.... 1 4.884 498.68 315.82
## - Imidazolepropionic.acid 1 4.885 498.68 315.82
## - N.acetyl.aspartic.acid 1 5.325 499.12 316.08
## - Indoxyl.sulfate 1 5.491 499.29 316.17
## - Cholesterol.sulfate 1 5.977 499.78 316.46
## - Phenylethylamine 1 5.996 499.80 316.47
## - Phenylacetylglutamine.PAGln. 1 6.689 500.49 316.88
## + X4.Ethylphenyl.sulfate 1 0.090 493.71 316.88
## + X4.Hydroxyphenylpropionate 1 0.060 493.74 316.90
## + S.gosine.1.phosphate_b 1 0.047 493.75 316.91
## + p.Cresol.glucuronide 1 0.037 493.76 316.91
## + BASO.... 1 0.028 493.77 316.92
## + Dopamine 1 0.025 493.77 316.92
## + X3.Hydroxyphenylacetic.acid 1 0.020 493.78 316.92
## + LDL.C..mM. 1 0.015 493.78 316.92
## + Urea..mM. 1 0.008 493.79 316.93
## + Biliverdin 1 0.001 493.80 316.93
## + Enterolactone 1 0.000 493.80 316.93
## - X3.Hydroxyhippuric.acid 1 7.562 501.36 317.39
## - X3.Hydroxyanthranilic.acid 1 7.651 501.45 317.44
## - Xanthurenic.acid 1 7.774 501.57 317.51
## - Gamma.aminobutyric.acid 1 8.214 502.01 317.77
## - Octadecanamide 1 8.624 502.42 318.01
## - Kynurenic.acid 1 8.684 502.48 318.04
## - Indole.3.carboxaldehyde 1 8.743 502.54 318.08
## - Oleamide 1 8.787 502.59 318.10
## - S.ganine.1.phosphate_b 1 9.851 503.65 318.72
## - Ascorbic.acid 1 10.934 504.73 319.35
## - Sphinganine 1 11.307 505.11 319.57
## - LYMPH.... 1 11.980 505.78 319.96
## - NEUT.... 1 12.195 505.99 320.08
## - AST..U.L. 1 13.902 507.70 321.07
## - X5.Aminopentanoic.acid 1 14.217 508.02 321.25
## - Acetylglycine 1 16.412 510.21 322.51
## - Phenyl.sulfate 1 16.726 510.53 322.69
## - Pantothenol 1 17.568 511.37 323.18
## - ALT..U.L. 1 21.815 515.61 325.60
## - X3.Hydroxypropionic.acid 1 23.262 517.06 326.42
## - X3..3.Hydroxyphenyl..3.hydroxypropanoic.acid 1 23.534 517.33 326.58
## - X1.5.Anhydrosorbitol 1 26.019 519.82 327.98
## - Palmitoylethanolamide 1 26.069 519.87 328.01
## - HDL.C..mM. 1 27.711 521.51 328.93
## - Indole.3.acrylic.acid 1 38.353 532.15 334.85
## - X3.Indolebutyric.acid 1 54.264 548.06 343.48
## - TG..mM. 1 72.229 566.03 352.93
##
## Step: AIC=312.97
## FBG..mM. ~ ALT..U.L. + AST..U.L. + Cre..uM. + UA..uM. + ALB..g.L. +
## TC..mM. + TG..mM. + HDL.C..mM. + ALP..U.L. + Υ.GT..U.L. +
## T.BIL..uM. + D.BIL..uM. + TBA..uM. + CHE..U.L. + WBC..10.9.L. +
## NEUT.... + LYMPH.... + EO.... + Phenylethylamine + Octadecanamide +
## Urocanic.acid + Imidazolepropionic.acid + Indole.3.carboxaldehyde +
## X3.Hydroxyanthranilic.acid + Oleamide + Palmitic.amide +
## Palmitoylethanolamide + Stearoylethanolamide + Bilirubin...47 +
## Indole.3.acrylic.acid + Kynurenic.acid + Indole.3.propionic.acid +
## Indole.3.methyl.acetate + Dopa + Sphinganine + Sphinganine.1.phosphate +
## Sphingosine + X3.Indolebutyric.acid + Sphingosine.1.phosphate +
## X5.Methoxyindoleacetate + Phenylacetylglutamine.PAGln. +
## Pantothenol + Putrescine + Gamma.aminobutyric.acid + X5.Aminopentanoic.acid +
## N.Acetylcadaverine + Acetylcholine + Spermidine + N.acetyl.aspartic.acid +
## N8.Acetylspermidine + Spermine + Phenol + p.Cresol + X1.5.Anhydrosorbitol +
## Benzoic.acid + Phenylacetic.acid + X3.Hydroxybenzoic.acid +
## X4.Hydroxybenzoic.acid + Salicylic.acid + Phenyllactate +
## Bilirubin...82 + X3..3.Hydroxyphenyl..3.hydroxypropanoic.acid +
## X4.Hydroxyphenyllactate + p.Cresol.sulfate + X2.Hydroxy.Hippuric.Acid +
## X3.Hydroxyhippuric.acid + S.ganine.1.phosphate_b + Cholesterol.sulfate +
## Xanthurenic.acid + Cinnamoylglycine + Indoxyl.sulfate + Ascorbic.acid +
## Homovanillic.acid.sulfate + Iodide + Phenyl.sulfate + X4.Hydroxybenzoic.acid.4.O.sulphate +
## X3.Hydroxypropionic.acid + Acetylglycine + Hippuric.acid
##
## Df Sum of Sq RSS AIC
## - WBC..10.9.L. 1 0.083 493.95 311.02
## - Dopa 1 0.097 493.96 311.03
## - Υ.GT..U.L. 1 0.101 493.97 311.03
## - UA..uM. 1 0.105 493.97 311.03
## - Sphingosine 1 0.159 494.02 311.07
## - Phenylacetic.acid 1 0.160 494.03 311.07
## - TC..mM. 1 0.168 494.03 311.07
## - X4.Hydroxybenzoic.acid 1 0.197 494.06 311.09
## - Putrescine 1 0.206 494.07 311.09
## - Palmitic.amide 1 0.265 494.13 311.13
## - Benzoic.acid 1 0.269 494.13 311.13
## - p.Cresol 1 0.275 494.14 311.14
## - p.Cresol.sulfate 1 0.292 494.16 311.15
## - CHE..U.L. 1 0.325 494.19 311.17
## - Stearoylethanolamide 1 0.490 494.36 311.26
## - Sphingosine.1.phosphate 1 0.511 494.38 311.28
## - Indole.3.propionic.acid 1 0.618 494.48 311.34
## - Spermidine 1 0.771 494.64 311.43
## - Spermine 1 0.828 494.69 311.46
## - X4.Hydroxyphenyllactate 1 0.854 494.72 311.48
## - X3.Hydroxybenzoic.acid 1 0.857 494.72 311.48
## - X5.Methoxyindoleacetate 1 0.905 494.77 311.51
## - Iodide 1 0.965 494.83 311.54
## - Salicylic.acid 1 1.101 494.97 311.63
## - Hippuric.acid 1 1.511 495.38 311.87
## - Phenol 1 1.572 495.44 311.90
## - Cre..uM. 1 1.573 495.44 311.90
## - Urocanic.acid 1 2.043 495.91 312.18
## - X4.Hydroxybenzoic.acid.4.O.sulphate 1 2.061 495.93 312.19
## - ALB..g.L. 1 2.256 496.12 312.31
## - Bilirubin...47 1 2.258 496.12 312.31
## - Acetylcholine 1 2.574 496.44 312.50
## - ALP..U.L. 1 2.601 496.47 312.51
## - N8.Acetylspermidine 1 2.606 496.47 312.51
## - Sphinganine.1.phosphate 1 2.817 496.68 312.64
## - Indole.3.methyl.acetate 1 2.826 496.69 312.64
## - N.Acetylcadaverine 1 3.033 496.90 312.77
## - TBA..uM. 1 3.304 497.17 312.93
## <none> 493.87 312.97
## - Homovanillic.acid.sulfate 1 3.412 497.28 312.99
## - Bilirubin...82 1 3.433 497.30 313.00
## - Phenyllactate 1 4.501 498.37 313.63
## - Cinnamoylglycine 1 4.578 498.44 313.68
## - T.BIL..uM. 1 4.620 498.49 313.70
## - X2.Hydroxy.Hippuric.Acid 1 4.666 498.53 313.73
## - D.BIL..uM. 1 4.757 498.62 313.78
## - EO.... 1 4.838 498.70 313.83
## - Imidazolepropionic.acid 1 4.875 498.74 313.85
## - N.acetyl.aspartic.acid 1 5.364 499.23 314.14
## - Indoxyl.sulfate 1 5.427 499.29 314.17
## - Phenylethylamine 1 6.002 499.87 314.51
## - Cholesterol.sulfate 1 6.094 499.96 314.57
## - Phenylacetylglutamine.PAGln. 1 6.641 500.51 314.89
## + X4.Hydroxyphenylpropionate 1 0.074 493.79 314.93
## + Oleoylethanolamide 1 0.066 493.80 314.93
## + X4.Ethylphenyl.sulfate 1 0.054 493.81 314.94
## + S.gosine.1.phosphate_b 1 0.052 493.81 314.94
## + BASO.... 1 0.033 493.83 314.95
## + p.Cresol.glucuronide 1 0.027 493.84 314.96
## + LDL.C..mM. 1 0.020 493.85 314.96
## + Dopamine 1 0.017 493.85 314.96
## + X3.Hydroxyphenylacetic.acid 1 0.016 493.85 314.96
## + Urea..mM. 1 0.005 493.86 314.97
## + Biliverdin 1 0.000 493.87 314.97
## + Enterolactone 1 0.000 493.87 314.97
## - X3.Hydroxyhippuric.acid 1 7.629 501.49 315.46
## - X3.Hydroxyanthranilic.acid 1 7.706 501.57 315.51
## - Xanthurenic.acid 1 7.781 501.65 315.55
## - Gamma.aminobutyric.acid 1 8.166 502.03 315.78
## - Octadecanamide 1 8.564 502.43 316.01
## - Kynurenic.acid 1 8.650 502.52 316.06
## - Oleamide 1 8.785 502.65 316.14
## - Indole.3.carboxaldehyde 1 9.142 503.01 316.35
## - S.ganine.1.phosphate_b 1 9.903 503.77 316.79
## - Ascorbic.acid 1 11.065 504.93 317.46
## - Sphinganine 1 11.322 505.19 317.61
## - LYMPH.... 1 11.921 505.79 317.96
## - NEUT.... 1 12.141 506.01 318.09
## - AST..U.L. 1 14.041 507.91 319.19
## - X5.Aminopentanoic.acid 1 14.280 508.15 319.32
## - Acetylglycine 1 16.499 510.36 320.60
## - Phenyl.sulfate 1 16.683 510.55 320.71
## - Pantothenol 1 17.734 511.60 321.31
## - ALT..U.L. 1 22.350 516.22 323.94
## - X3.Hydroxypropionic.acid 1 23.210 517.08 324.43
## - X3..3.Hydroxyphenyl..3.hydroxypropanoic.acid 1 23.542 517.41 324.62
## - X1.5.Anhydrosorbitol 1 26.259 520.12 326.15
## - HDL.C..mM. 1 27.957 521.82 327.11
## - Indole.3.acrylic.acid 1 38.305 532.17 332.86
## - Palmitoylethanolamide 1 40.011 533.88 333.80
## - X3.Indolebutyric.acid 1 54.297 548.16 341.54
## - TG..mM. 1 72.712 566.58 351.22
##
## Step: AIC=311.02
## FBG..mM. ~ ALT..U.L. + AST..U.L. + Cre..uM. + UA..uM. + ALB..g.L. +
## TC..mM. + TG..mM. + HDL.C..mM. + ALP..U.L. + Υ.GT..U.L. +
## T.BIL..uM. + D.BIL..uM. + TBA..uM. + CHE..U.L. + NEUT.... +
## LYMPH.... + EO.... + Phenylethylamine + Octadecanamide +
## Urocanic.acid + Imidazolepropionic.acid + Indole.3.carboxaldehyde +
## X3.Hydroxyanthranilic.acid + Oleamide + Palmitic.amide +
## Palmitoylethanolamide + Stearoylethanolamide + Bilirubin...47 +
## Indole.3.acrylic.acid + Kynurenic.acid + Indole.3.propionic.acid +
## Indole.3.methyl.acetate + Dopa + Sphinganine + Sphinganine.1.phosphate +
## Sphingosine + X3.Indolebutyric.acid + Sphingosine.1.phosphate +
## X5.Methoxyindoleacetate + Phenylacetylglutamine.PAGln. +
## Pantothenol + Putrescine + Gamma.aminobutyric.acid + X5.Aminopentanoic.acid +
## N.Acetylcadaverine + Acetylcholine + Spermidine + N.acetyl.aspartic.acid +
## N8.Acetylspermidine + Spermine + Phenol + p.Cresol + X1.5.Anhydrosorbitol +
## Benzoic.acid + Phenylacetic.acid + X3.Hydroxybenzoic.acid +
## X4.Hydroxybenzoic.acid + Salicylic.acid + Phenyllactate +
## Bilirubin...82 + X3..3.Hydroxyphenyl..3.hydroxypropanoic.acid +
## X4.Hydroxyphenyllactate + p.Cresol.sulfate + X2.Hydroxy.Hippuric.Acid +
## X3.Hydroxyhippuric.acid + S.ganine.1.phosphate_b + Cholesterol.sulfate +
## Xanthurenic.acid + Cinnamoylglycine + Indoxyl.sulfate + Ascorbic.acid +
## Homovanillic.acid.sulfate + Iodide + Phenyl.sulfate + X4.Hydroxybenzoic.acid.4.O.sulphate +
## X3.Hydroxypropionic.acid + Acetylglycine + Hippuric.acid
##
## Df Sum of Sq RSS AIC
## - UA..uM. 1 0.093 494.04 309.08
## - Dopa 1 0.097 494.05 309.08
## - Υ.GT..U.L. 1 0.100 494.05 309.08
## - Sphingosine 1 0.147 494.10 309.11
## - Phenylacetic.acid 1 0.155 494.10 309.11
## - TC..mM. 1 0.172 494.12 309.12
## - Putrescine 1 0.182 494.13 309.13
## - X4.Hydroxybenzoic.acid 1 0.219 494.17 309.15
## - Benzoic.acid 1 0.260 494.21 309.18
## - p.Cresol 1 0.261 494.21 309.18
## - Palmitic.amide 1 0.272 494.22 309.18
## - p.Cresol.sulfate 1 0.331 494.28 309.22
## - CHE..U.L. 1 0.353 494.30 309.23
## - Stearoylethanolamide 1 0.449 494.40 309.29
## - Sphingosine.1.phosphate 1 0.559 494.51 309.35
## - Indole.3.propionic.acid 1 0.643 494.59 309.40
## - Spermine 1 0.767 494.72 309.48
## - Spermidine 1 0.777 494.73 309.48
## - X3.Hydroxybenzoic.acid 1 0.850 494.80 309.53
## - X4.Hydroxyphenyllactate 1 0.856 494.80 309.53
## - X5.Methoxyindoleacetate 1 0.890 494.84 309.55
## - Iodide 1 0.974 494.92 309.60
## - Salicylic.acid 1 1.157 495.11 309.71
## - Hippuric.acid 1 1.479 495.43 309.90
## - Cre..uM. 1 1.504 495.45 309.91
## - Phenol 1 1.671 495.62 310.01
## - Urocanic.acid 1 2.046 495.99 310.23
## - X4.Hydroxybenzoic.acid.4.O.sulphate 1 2.142 496.09 310.29
## - ALB..g.L. 1 2.244 496.19 310.35
## - Bilirubin...47 1 2.325 496.27 310.40
## - Acetylcholine 1 2.503 496.45 310.50
## - N8.Acetylspermidine 1 2.663 496.61 310.60
## - ALP..U.L. 1 2.670 496.62 310.60
## - Sphinganine.1.phosphate 1 2.841 496.79 310.70
## - Indole.3.methyl.acetate 1 2.845 496.79 310.70
## - N.Acetylcadaverine 1 2.979 496.93 310.78
## - TBA..uM. 1 3.222 497.17 310.93
## <none> 493.95 311.02
## - Homovanillic.acid.sulfate 1 3.395 497.34 311.03
## - Bilirubin...82 1 3.473 497.42 311.07
## - Cinnamoylglycine 1 4.529 498.48 311.70
## - Phenyllactate 1 4.557 498.51 311.71
## - X2.Hydroxy.Hippuric.Acid 1 4.733 498.68 311.82
## - EO.... 1 4.759 498.71 311.83
## - Imidazolepropionic.acid 1 4.796 498.74 311.85
## - T.BIL..uM. 1 4.855 498.80 311.89
## - D.BIL..uM. 1 5.009 498.96 311.98
## - N.acetyl.aspartic.acid 1 5.309 499.26 312.15
## - Indoxyl.sulfate 1 5.347 499.30 312.18
## - Cholesterol.sulfate 1 6.011 499.96 312.57
## - Phenylethylamine 1 6.172 500.12 312.66
## + WBC..10.9.L. 1 0.083 493.87 312.97
## + X4.Hydroxyphenylpropionate 1 0.073 493.87 312.98
## + Oleoylethanolamide 1 0.071 493.88 312.98
## + S.gosine.1.phosphate_b 1 0.063 493.89 312.98
## + BASO.... 1 0.036 493.91 313.00
## + X4.Ethylphenyl.sulfate 1 0.032 493.92 313.00
## + p.Cresol.glucuronide 1 0.031 493.92 313.00
## + X3.Hydroxyphenylacetic.acid 1 0.023 493.92 313.01
## + LDL.C..mM. 1 0.019 493.93 313.01
## + Dopamine 1 0.010 493.94 313.02
## + Urea..mM. 1 0.003 493.95 313.02
## + Biliverdin 1 0.000 493.95 313.02
## + Enterolactone 1 0.000 493.95 313.02
## - Phenylacetylglutamine.PAGln. 1 6.833 500.78 313.05
## - X3.Hydroxyanthranilic.acid 1 7.894 501.84 313.67
## - Gamma.aminobutyric.acid 1 8.084 502.03 313.78
## - Xanthurenic.acid 1 8.193 502.14 313.84
## - X3.Hydroxyhippuric.acid 1 8.203 502.15 313.85
## - Octadecanamide 1 8.499 502.45 314.02
## - Oleamide 1 8.707 502.66 314.14
## - Kynurenic.acid 1 8.874 502.82 314.24
## - Indole.3.carboxaldehyde 1 9.105 503.05 314.37
## - S.ganine.1.phosphate_b 1 10.237 504.19 315.03
## - Ascorbic.acid 1 11.077 505.02 315.52
## - Sphinganine 1 11.281 505.23 315.64
## - LYMPH.... 1 11.865 505.81 315.98
## - NEUT.... 1 12.161 506.11 316.15
## - X5.Aminopentanoic.acid 1 14.277 508.23 317.37
## - AST..U.L. 1 14.462 508.41 317.48
## - Acetylglycine 1 16.499 510.45 318.65
## - Phenyl.sulfate 1 16.693 510.64 318.76
## - Pantothenol 1 17.693 511.64 319.33
## - ALT..U.L. 1 23.056 517.00 322.39
## - X3.Hydroxypropionic.acid 1 23.177 517.13 322.46
## - X3..3.Hydroxyphenyl..3.hydroxypropanoic.acid 1 24.310 518.26 323.10
## - X1.5.Anhydrosorbitol 1 26.194 520.14 324.16
## - HDL.C..mM. 1 27.880 521.83 325.11
## - Indole.3.acrylic.acid 1 38.889 532.84 331.23
## - Palmitoylethanolamide 1 40.010 533.96 331.84
## - X3.Indolebutyric.acid 1 54.216 548.16 339.54
## - TG..mM. 1 73.429 567.38 349.63
##
## Step: AIC=309.08
## FBG..mM. ~ ALT..U.L. + AST..U.L. + Cre..uM. + ALB..g.L. + TC..mM. +
## TG..mM. + HDL.C..mM. + ALP..U.L. + Υ.GT..U.L. + T.BIL..uM. +
## D.BIL..uM. + TBA..uM. + CHE..U.L. + NEUT.... + LYMPH.... +
## EO.... + Phenylethylamine + Octadecanamide + Urocanic.acid +
## Imidazolepropionic.acid + Indole.3.carboxaldehyde + X3.Hydroxyanthranilic.acid +
## Oleamide + Palmitic.amide + Palmitoylethanolamide + Stearoylethanolamide +
## Bilirubin...47 + Indole.3.acrylic.acid + Kynurenic.acid +
## Indole.3.propionic.acid + Indole.3.methyl.acetate + Dopa +
## Sphinganine + Sphinganine.1.phosphate + Sphingosine + X3.Indolebutyric.acid +
## Sphingosine.1.phosphate + X5.Methoxyindoleacetate + Phenylacetylglutamine.PAGln. +
## Pantothenol + Putrescine + Gamma.aminobutyric.acid + X5.Aminopentanoic.acid +
## N.Acetylcadaverine + Acetylcholine + Spermidine + N.acetyl.aspartic.acid +
## N8.Acetylspermidine + Spermine + Phenol + p.Cresol + X1.5.Anhydrosorbitol +
## Benzoic.acid + Phenylacetic.acid + X3.Hydroxybenzoic.acid +
## X4.Hydroxybenzoic.acid + Salicylic.acid + Phenyllactate +
## Bilirubin...82 + X3..3.Hydroxyphenyl..3.hydroxypropanoic.acid +
## X4.Hydroxyphenyllactate + p.Cresol.sulfate + X2.Hydroxy.Hippuric.Acid +
## X3.Hydroxyhippuric.acid + S.ganine.1.phosphate_b + Cholesterol.sulfate +
## Xanthurenic.acid + Cinnamoylglycine + Indoxyl.sulfate + Ascorbic.acid +
## Homovanillic.acid.sulfate + Iodide + Phenyl.sulfate + X4.Hydroxybenzoic.acid.4.O.sulphate +
## X3.Hydroxypropionic.acid + Acetylglycine + Hippuric.acid
##
## Df Sum of Sq RSS AIC
## - Υ.GT..U.L. 1 0.100 494.14 307.14
## - Dopa 1 0.108 494.15 307.14
## - TC..mM. 1 0.151 494.19 307.17
## - Phenylacetic.acid 1 0.157 494.20 307.17
## - Sphingosine 1 0.166 494.21 307.18
## - Putrescine 1 0.190 494.23 307.19
## - X4.Hydroxybenzoic.acid 1 0.217 494.26 307.21
## - Palmitic.amide 1 0.255 494.30 307.23
## - p.Cresol 1 0.280 494.32 307.24
## - Benzoic.acid 1 0.300 494.34 307.25
## - p.Cresol.sulfate 1 0.306 494.35 307.26
## - CHE..U.L. 1 0.382 494.42 307.30
## - Stearoylethanolamide 1 0.451 494.49 307.34
## - Sphingosine.1.phosphate 1 0.603 494.64 307.43
## - Indole.3.propionic.acid 1 0.672 494.71 307.48
## - Spermidine 1 0.746 494.79 307.52
## - Spermine 1 0.775 494.82 307.54
## - X4.Hydroxyphenyllactate 1 0.820 494.86 307.56
## - X3.Hydroxybenzoic.acid 1 0.844 494.89 307.58
## - X5.Methoxyindoleacetate 1 0.866 494.91 307.59
## - Iodide 1 0.939 494.98 307.63
## - Salicylic.acid 1 1.148 495.19 307.76
## - Cre..uM. 1 1.419 495.46 307.92
## - Hippuric.acid 1 1.538 495.58 307.99
## - Phenol 1 1.695 495.74 308.08
## - Urocanic.acid 1 2.128 496.17 308.34
## - X4.Hydroxybenzoic.acid.4.O.sulphate 1 2.220 496.26 308.39
## - ALB..g.L. 1 2.247 496.29 308.41
## - Bilirubin...47 1 2.429 496.47 308.51
## - Acetylcholine 1 2.466 496.51 308.54
## - ALP..U.L. 1 2.634 496.68 308.63
## - Sphinganine.1.phosphate 1 2.749 496.79 308.70
## - N8.Acetylspermidine 1 2.750 496.79 308.70
## - N.Acetylcadaverine 1 2.890 496.93 308.79
## - Indole.3.methyl.acetate 1 2.915 496.96 308.80
## - TBA..uM. 1 3.247 497.29 309.00
## - Homovanillic.acid.sulfate 1 3.359 497.40 309.06
## <none> 494.04 309.08
## - Bilirubin...82 1 3.569 497.61 309.19
## - Cinnamoylglycine 1 4.494 498.54 309.73
## - Phenyllactate 1 4.657 498.70 309.83
## - X2.Hydroxy.Hippuric.Acid 1 4.687 498.73 309.84
## - EO.... 1 4.693 498.73 309.85
## - Imidazolepropionic.acid 1 4.915 498.96 309.98
## - T.BIL..uM. 1 5.171 499.21 310.13
## - Indoxyl.sulfate 1 5.254 499.30 310.18
## - N.acetyl.aspartic.acid 1 5.259 499.30 310.18
## - D.BIL..uM. 1 5.330 499.37 310.22
## - Cholesterol.sulfate 1 5.956 500.00 310.59
## - Phenylethylamine 1 6.204 500.25 310.73
## + UA..uM. 1 0.093 493.95 311.02
## + Oleoylethanolamide 1 0.083 493.96 311.03
## + WBC..10.9.L. 1 0.071 493.97 311.03
## + S.gosine.1.phosphate_b 1 0.062 493.98 311.04
## + X4.Hydroxyphenylpropionate 1 0.059 493.98 311.04
## + BASO.... 1 0.042 494.00 311.05
## + p.Cresol.glucuronide 1 0.033 494.01 311.06
## + X3.Hydroxyphenylacetic.acid 1 0.029 494.01 311.06
## + X4.Ethylphenyl.sulfate 1 0.026 494.01 311.06
## - Phenylacetylglutamine.PAGln. 1 6.765 500.81 311.06
## + LDL.C..mM. 1 0.016 494.02 311.07
## + Dopamine 1 0.006 494.04 311.07
## + Urea..mM. 1 0.004 494.04 311.07
## + Biliverdin 1 0.000 494.04 311.08
## + Enterolactone 1 0.000 494.04 311.08
## - X3.Hydroxyanthranilic.acid 1 7.889 501.93 311.72
## - Xanthurenic.acid 1 8.159 502.20 311.88
## - Gamma.aminobutyric.acid 1 8.174 502.21 311.88
## - Octadecanamide 1 8.518 502.56 312.09
## - X3.Hydroxyhippuric.acid 1 8.569 502.61 312.12
## - Oleamide 1 8.614 502.66 312.14
## - Kynurenic.acid 1 8.805 502.85 312.25
## - Indole.3.carboxaldehyde 1 9.018 503.06 312.38
## - S.ganine.1.phosphate_b 1 10.144 504.19 313.03
## - Ascorbic.acid 1 11.067 505.11 313.57
## - Sphinganine 1 11.444 505.49 313.79
## - LYMPH.... 1 11.854 505.89 314.02
## - NEUT.... 1 12.157 506.20 314.20
## - X5.Aminopentanoic.acid 1 14.732 508.77 315.69
## - AST..U.L. 1 14.784 508.83 315.72
## - Acetylglycine 1 16.522 510.56 316.72
## - Phenyl.sulfate 1 16.601 510.64 316.76
## - Pantothenol 1 17.744 511.79 317.42
## - X3.Hydroxypropionic.acid 1 23.086 517.13 320.46
## - ALT..U.L. 1 24.242 518.28 321.11
## - X3..3.Hydroxyphenyl..3.hydroxypropanoic.acid 1 24.593 518.63 321.31
## - X1.5.Anhydrosorbitol 1 26.286 520.33 322.27
## - HDL.C..mM. 1 27.798 521.84 323.12
## - Indole.3.acrylic.acid 1 38.839 532.88 329.25
## - Palmitoylethanolamide 1 40.171 534.21 329.98
## - X3.Indolebutyric.acid 1 54.765 548.81 337.88
## - TG..mM. 1 80.108 574.15 351.11
##
## Step: AIC=307.14
## FBG..mM. ~ ALT..U.L. + AST..U.L. + Cre..uM. + ALB..g.L. + TC..mM. +
## TG..mM. + HDL.C..mM. + ALP..U.L. + T.BIL..uM. + D.BIL..uM. +
## TBA..uM. + CHE..U.L. + NEUT.... + LYMPH.... + EO.... + Phenylethylamine +
## Octadecanamide + Urocanic.acid + Imidazolepropionic.acid +
## Indole.3.carboxaldehyde + X3.Hydroxyanthranilic.acid + Oleamide +
## Palmitic.amide + Palmitoylethanolamide + Stearoylethanolamide +
## Bilirubin...47 + Indole.3.acrylic.acid + Kynurenic.acid +
## Indole.3.propionic.acid + Indole.3.methyl.acetate + Dopa +
## Sphinganine + Sphinganine.1.phosphate + Sphingosine + X3.Indolebutyric.acid +
## Sphingosine.1.phosphate + X5.Methoxyindoleacetate + Phenylacetylglutamine.PAGln. +
## Pantothenol + Putrescine + Gamma.aminobutyric.acid + X5.Aminopentanoic.acid +
## N.Acetylcadaverine + Acetylcholine + Spermidine + N.acetyl.aspartic.acid +
## N8.Acetylspermidine + Spermine + Phenol + p.Cresol + X1.5.Anhydrosorbitol +
## Benzoic.acid + Phenylacetic.acid + X3.Hydroxybenzoic.acid +
## X4.Hydroxybenzoic.acid + Salicylic.acid + Phenyllactate +
## Bilirubin...82 + X3..3.Hydroxyphenyl..3.hydroxypropanoic.acid +
## X4.Hydroxyphenyllactate + p.Cresol.sulfate + X2.Hydroxy.Hippuric.Acid +
## X3.Hydroxyhippuric.acid + S.ganine.1.phosphate_b + Cholesterol.sulfate +
## Xanthurenic.acid + Cinnamoylglycine + Indoxyl.sulfate + Ascorbic.acid +
## Homovanillic.acid.sulfate + Iodide + Phenyl.sulfate + X4.Hydroxybenzoic.acid.4.O.sulphate +
## X3.Hydroxypropionic.acid + Acetylglycine + Hippuric.acid
##
## Df Sum of Sq RSS AIC
## - Dopa 1 0.142 494.28 305.22
## - TC..mM. 1 0.153 494.29 305.23
## - Phenylacetic.acid 1 0.154 494.29 305.23
## - Sphingosine 1 0.164 494.30 305.23
## - Putrescine 1 0.203 494.34 305.26
## - X4.Hydroxybenzoic.acid 1 0.203 494.34 305.26
## - Benzoic.acid 1 0.275 494.42 305.30
## - p.Cresol.sulfate 1 0.291 494.43 305.31
## - Palmitic.amide 1 0.299 494.44 305.31
## - p.Cresol 1 0.303 494.44 305.32
## - CHE..U.L. 1 0.344 494.49 305.34
## - Stearoylethanolamide 1 0.452 494.59 305.40
## - Sphingosine.1.phosphate 1 0.607 494.75 305.50
## - Indole.3.propionic.acid 1 0.613 494.75 305.50
## - Spermidine 1 0.698 494.84 305.55
## - Spermine 1 0.776 494.92 305.60
## - X4.Hydroxyphenyllactate 1 0.832 494.97 305.63
## - X5.Methoxyindoleacetate 1 0.843 494.98 305.64
## - X3.Hydroxybenzoic.acid 1 0.891 495.03 305.66
## - Iodide 1 0.961 495.10 305.71
## - Salicylic.acid 1 1.109 495.25 305.79
## - Cre..uM. 1 1.374 495.51 305.95
## - Hippuric.acid 1 1.537 495.68 306.05
## - Phenol 1 1.693 495.83 306.14
## - Urocanic.acid 1 2.150 496.29 306.41
## - X4.Hydroxybenzoic.acid.4.O.sulphate 1 2.175 496.32 306.42
## - ALB..g.L. 1 2.243 496.38 306.46
## - Acetylcholine 1 2.413 496.55 306.56
## - Bilirubin...47 1 2.508 496.65 306.62
## - ALP..U.L. 1 2.550 496.69 306.64
## - N8.Acetylspermidine 1 2.735 496.88 306.75
## - Sphinganine.1.phosphate 1 2.813 496.95 306.80
## - Indole.3.methyl.acetate 1 2.822 496.96 306.80
## - N.Acetylcadaverine 1 3.134 497.28 306.99
## - TBA..uM. 1 3.283 497.42 307.08
## - Homovanillic.acid.sulfate 1 3.356 497.50 307.12
## <none> 494.14 307.14
## - Bilirubin...82 1 3.663 497.80 307.30
## - Phenyllactate 1 4.567 498.71 307.83
## - X2.Hydroxy.Hippuric.Acid 1 4.613 498.75 307.86
## - Cinnamoylglycine 1 4.647 498.79 307.88
## - EO.... 1 4.693 498.83 307.91
## - Imidazolepropionic.acid 1 4.844 498.98 307.99
## - N.acetyl.aspartic.acid 1 5.175 499.32 308.19
## - T.BIL..uM. 1 5.253 499.39 308.23
## - D.BIL..uM. 1 5.405 499.55 308.32
## - Indoxyl.sulfate 1 5.414 499.56 308.33
## - Cholesterol.sulfate 1 5.991 500.13 308.67
## - Phenylethylamine 1 6.173 500.31 308.77
## + Υ.GT..U.L. 1 0.100 494.04 309.08
## + UA..uM. 1 0.093 494.05 309.08
## + Oleoylethanolamide 1 0.086 494.06 309.09
## + WBC..10.9.L. 1 0.070 494.07 309.09
## + X4.Hydroxyphenylpropionate 1 0.067 494.07 309.10
## + S.gosine.1.phosphate_b 1 0.052 494.09 309.11
## + BASO.... 1 0.049 494.09 309.11
## + X3.Hydroxyphenylacetic.acid 1 0.036 494.10 309.11
## + X4.Ethylphenyl.sulfate 1 0.025 494.12 309.12
## + p.Cresol.glucuronide 1 0.025 494.12 309.12
## + LDL.C..mM. 1 0.014 494.13 309.13
## + Urea..mM. 1 0.005 494.14 309.13
## + Dopamine 1 0.004 494.14 309.13
## + Biliverdin 1 0.001 494.14 309.14
## + Enterolactone 1 0.000 494.14 309.14
## - Phenylacetylglutamine.PAGln. 1 6.967 501.11 309.24
## - X3.Hydroxyanthranilic.acid 1 7.882 502.02 309.77
## - Xanthurenic.acid 1 8.097 502.24 309.90
## - Gamma.aminobutyric.acid 1 8.348 502.49 310.04
## - X3.Hydroxyhippuric.acid 1 8.469 502.61 310.12
## - Octadecanamide 1 8.590 502.73 310.19
## - Oleamide 1 8.605 502.75 310.19
## - Kynurenic.acid 1 8.820 502.96 310.32
## - Indole.3.carboxaldehyde 1 9.066 503.21 310.46
## - S.ganine.1.phosphate_b 1 10.168 504.31 311.10
## - Ascorbic.acid 1 11.324 505.46 311.77
## - Sphinganine 1 11.495 505.64 311.87
## - LYMPH.... 1 11.916 506.06 312.12
## - NEUT.... 1 12.232 506.37 312.30
## - X5.Aminopentanoic.acid 1 14.652 508.79 313.70
## - AST..U.L. 1 14.765 508.91 313.76
## - Acetylglycine 1 16.465 510.61 314.74
## - Phenyl.sulfate 1 16.617 510.76 314.83
## - Pantothenol 1 17.963 512.10 315.60
## - X3.Hydroxypropionic.acid 1 23.072 517.21 318.51
## - X3..3.Hydroxyphenyl..3.hydroxypropanoic.acid 1 24.509 518.65 319.32
## - ALT..U.L. 1 24.991 519.13 319.59
## - X1.5.Anhydrosorbitol 1 26.340 520.48 320.35
## - HDL.C..mM. 1 27.706 521.85 321.12
## - Indole.3.acrylic.acid 1 38.846 532.99 327.31
## - Palmitoylethanolamide 1 40.195 534.34 328.05
## - X3.Indolebutyric.acid 1 55.016 549.16 336.07
## - TG..mM. 1 80.339 574.48 349.27
##
## Step: AIC=305.22
## FBG..mM. ~ ALT..U.L. + AST..U.L. + Cre..uM. + ALB..g.L. + TC..mM. +
## TG..mM. + HDL.C..mM. + ALP..U.L. + T.BIL..uM. + D.BIL..uM. +
## TBA..uM. + CHE..U.L. + NEUT.... + LYMPH.... + EO.... + Phenylethylamine +
## Octadecanamide + Urocanic.acid + Imidazolepropionic.acid +
## Indole.3.carboxaldehyde + X3.Hydroxyanthranilic.acid + Oleamide +
## Palmitic.amide + Palmitoylethanolamide + Stearoylethanolamide +
## Bilirubin...47 + Indole.3.acrylic.acid + Kynurenic.acid +
## Indole.3.propionic.acid + Indole.3.methyl.acetate + Sphinganine +
## Sphinganine.1.phosphate + Sphingosine + X3.Indolebutyric.acid +
## Sphingosine.1.phosphate + X5.Methoxyindoleacetate + Phenylacetylglutamine.PAGln. +
## Pantothenol + Putrescine + Gamma.aminobutyric.acid + X5.Aminopentanoic.acid +
## N.Acetylcadaverine + Acetylcholine + Spermidine + N.acetyl.aspartic.acid +
## N8.Acetylspermidine + Spermine + Phenol + p.Cresol + X1.5.Anhydrosorbitol +
## Benzoic.acid + Phenylacetic.acid + X3.Hydroxybenzoic.acid +
## X4.Hydroxybenzoic.acid + Salicylic.acid + Phenyllactate +
## Bilirubin...82 + X3..3.Hydroxyphenyl..3.hydroxypropanoic.acid +
## X4.Hydroxyphenyllactate + p.Cresol.sulfate + X2.Hydroxy.Hippuric.Acid +
## X3.Hydroxyhippuric.acid + S.ganine.1.phosphate_b + Cholesterol.sulfate +
## Xanthurenic.acid + Cinnamoylglycine + Indoxyl.sulfate + Ascorbic.acid +
## Homovanillic.acid.sulfate + Iodide + Phenyl.sulfate + X4.Hydroxybenzoic.acid.4.O.sulphate +
## X3.Hydroxypropionic.acid + Acetylglycine + Hippuric.acid
##
## Df Sum of Sq RSS AIC
## - Phenylacetic.acid 1 0.130 494.41 303.30
## - TC..mM. 1 0.148 494.43 303.31
## - Sphingosine 1 0.159 494.44 303.31
## - X4.Hydroxybenzoic.acid 1 0.229 494.51 303.36
## - Putrescine 1 0.234 494.52 303.36
## - Palmitic.amide 1 0.249 494.53 303.37
## - p.Cresol 1 0.273 494.56 303.38
## - Benzoic.acid 1 0.315 494.60 303.41
## - CHE..U.L. 1 0.351 494.63 303.43
## - p.Cresol.sulfate 1 0.357 494.64 303.43
## - Stearoylethanolamide 1 0.475 494.76 303.50
## - Indole.3.propionic.acid 1 0.610 494.89 303.58
## - Sphingosine.1.phosphate 1 0.648 494.93 303.60
## - Spermine 1 0.702 494.98 303.64
## - X5.Methoxyindoleacetate 1 0.757 495.04 303.67
## - Spermidine 1 0.776 495.06 303.68
## - X4.Hydroxyphenyllactate 1 0.813 495.10 303.70
## - Iodide 1 0.926 495.21 303.77
## - X3.Hydroxybenzoic.acid 1 0.948 495.23 303.78
## - Salicylic.acid 1 1.180 495.46 303.92
## - Hippuric.acid 1 1.426 495.71 304.06
## - Cre..uM. 1 1.537 495.82 304.13
## - Phenol 1 1.733 496.02 304.25
## - X4.Hydroxybenzoic.acid.4.O.sulphate 1 2.122 496.40 304.48
## - ALB..g.L. 1 2.165 496.45 304.50
## - Urocanic.acid 1 2.335 496.62 304.60
## - Bilirubin...47 1 2.415 496.70 304.65
## - ALP..U.L. 1 2.681 496.96 304.80
## - N8.Acetylspermidine 1 2.685 496.97 304.81
## - Indole.3.methyl.acetate 1 2.820 497.10 304.89
## - Sphinganine.1.phosphate 1 2.838 497.12 304.90
## - Acetylcholine 1 3.045 497.33 305.02
## - TBA..uM. 1 3.256 497.54 305.14
## - N.Acetylcadaverine 1 3.373 497.66 305.21
## <none> 494.28 305.22
## - Homovanillic.acid.sulfate 1 3.534 497.82 305.31
## - Bilirubin...82 1 3.607 497.89 305.35
## - Phenyllactate 1 4.561 498.84 305.91
## - Cinnamoylglycine 1 4.599 498.88 305.93
## - EO.... 1 4.607 498.89 305.94
## - X2.Hydroxy.Hippuric.Acid 1 4.772 499.05 306.03
## - N.acetyl.aspartic.acid 1 5.059 499.34 306.20
## - T.BIL..uM. 1 5.131 499.41 306.25
## - D.BIL..uM. 1 5.324 499.61 306.36
## - Indoxyl.sulfate 1 5.494 499.78 306.46
## - Imidazolepropionic.acid 1 5.553 499.84 306.49
## - Cholesterol.sulfate 1 6.041 500.32 306.78
## - Phenylethylamine 1 6.121 500.40 306.83
## + Dopa 1 0.142 494.14 307.14
## + Υ.GT..U.L. 1 0.133 494.15 307.14
## + X4.Hydroxyphenylpropionate 1 0.107 494.18 307.16
## + UA..uM. 1 0.106 494.18 307.16
## + WBC..10.9.L. 1 0.070 494.21 307.18
## + BASO.... 1 0.067 494.22 307.18
## + Oleoylethanolamide 1 0.065 494.22 307.18
## + X3.Hydroxyphenylacetic.acid 1 0.049 494.23 307.19
## + S.gosine.1.phosphate_b 1 0.048 494.24 307.19
## + p.Cresol.glucuronide 1 0.044 494.24 307.19
## + X4.Ethylphenyl.sulfate 1 0.031 494.25 307.20
## + Urea..mM. 1 0.010 494.27 307.21
## + LDL.C..mM. 1 0.010 494.27 307.21
## + Dopamine 1 0.008 494.27 307.22
## + Biliverdin 1 0.000 494.28 307.22
## + Enterolactone 1 0.000 494.28 307.22
## - Phenylacetylglutamine.PAGln. 1 6.870 501.15 307.26
## - Xanthurenic.acid 1 8.081 502.36 307.97
## - X3.Hydroxyanthranilic.acid 1 8.253 502.54 308.07
## - Gamma.aminobutyric.acid 1 8.427 502.71 308.17
## - Octadecanamide 1 8.526 502.81 308.23
## - X3.Hydroxyhippuric.acid 1 8.587 502.87 308.27
## - Kynurenic.acid 1 8.682 502.96 308.32
## - Oleamide 1 8.763 503.05 308.37
## - Indole.3.carboxaldehyde 1 9.183 503.47 308.61
## - S.ganine.1.phosphate_b 1 10.200 504.48 309.20
## - Ascorbic.acid 1 11.216 505.50 309.79
## - Sphinganine 1 11.433 505.72 309.92
## - LYMPH.... 1 11.869 506.15 310.17
## - NEUT.... 1 12.288 506.57 310.42
## - AST..U.L. 1 14.807 509.09 311.87
## - Acetylglycine 1 16.337 510.62 312.75
## - Phenyl.sulfate 1 16.589 510.87 312.89
## - X5.Aminopentanoic.acid 1 16.591 510.87 312.89
## - Pantothenol 1 17.856 512.14 313.62
## - X3.Hydroxypropionic.acid 1 23.242 517.52 316.68
## - X3..3.Hydroxyphenyl..3.hydroxypropanoic.acid 1 24.656 518.94 317.48
## - ALT..U.L. 1 25.188 519.47 317.78
## - X1.5.Anhydrosorbitol 1 26.629 520.91 318.59
## - HDL.C..mM. 1 27.699 521.98 319.20
## - Indole.3.acrylic.acid 1 39.233 533.52 325.60
## - Palmitoylethanolamide 1 40.721 535.00 326.42
## - X3.Indolebutyric.acid 1 54.881 549.16 334.07
## - TG..mM. 1 80.313 574.60 347.33
##
## Step: AIC=303.3
## FBG..mM. ~ ALT..U.L. + AST..U.L. + Cre..uM. + ALB..g.L. + TC..mM. +
## TG..mM. + HDL.C..mM. + ALP..U.L. + T.BIL..uM. + D.BIL..uM. +
## TBA..uM. + CHE..U.L. + NEUT.... + LYMPH.... + EO.... + Phenylethylamine +
## Octadecanamide + Urocanic.acid + Imidazolepropionic.acid +
## Indole.3.carboxaldehyde + X3.Hydroxyanthranilic.acid + Oleamide +
## Palmitic.amide + Palmitoylethanolamide + Stearoylethanolamide +
## Bilirubin...47 + Indole.3.acrylic.acid + Kynurenic.acid +
## Indole.3.propionic.acid + Indole.3.methyl.acetate + Sphinganine +
## Sphinganine.1.phosphate + Sphingosine + X3.Indolebutyric.acid +
## Sphingosine.1.phosphate + X5.Methoxyindoleacetate + Phenylacetylglutamine.PAGln. +
## Pantothenol + Putrescine + Gamma.aminobutyric.acid + X5.Aminopentanoic.acid +
## N.Acetylcadaverine + Acetylcholine + Spermidine + N.acetyl.aspartic.acid +
## N8.Acetylspermidine + Spermine + Phenol + p.Cresol + X1.5.Anhydrosorbitol +
## Benzoic.acid + X3.Hydroxybenzoic.acid + X4.Hydroxybenzoic.acid +
## Salicylic.acid + Phenyllactate + Bilirubin...82 + X3..3.Hydroxyphenyl..3.hydroxypropanoic.acid +
## X4.Hydroxyphenyllactate + p.Cresol.sulfate + X2.Hydroxy.Hippuric.Acid +
## X3.Hydroxyhippuric.acid + S.ganine.1.phosphate_b + Cholesterol.sulfate +
## Xanthurenic.acid + Cinnamoylglycine + Indoxyl.sulfate + Ascorbic.acid +
## Homovanillic.acid.sulfate + Iodide + Phenyl.sulfate + X4.Hydroxybenzoic.acid.4.O.sulphate +
## X3.Hydroxypropionic.acid + Acetylglycine + Hippuric.acid
##
## Df Sum of Sq RSS AIC
## - TC..mM. 1 0.177 494.59 301.40
## - Sphingosine 1 0.186 494.60 301.41
## - X4.Hydroxybenzoic.acid 1 0.213 494.63 301.42
## - Palmitic.amide 1 0.230 494.64 301.43
## - p.Cresol 1 0.243 494.66 301.44
## - Putrescine 1 0.257 494.67 301.45
## - Benzoic.acid 1 0.289 494.70 301.47
## - CHE..U.L. 1 0.358 494.77 301.51
## - p.Cresol.sulfate 1 0.424 494.84 301.55
## - Stearoylethanolamide 1 0.466 494.88 301.57
## - Indole.3.propionic.acid 1 0.618 495.03 301.66
## - Spermine 1 0.663 495.08 301.69
## - Sphingosine.1.phosphate 1 0.667 495.08 301.69
## - X5.Methoxyindoleacetate 1 0.751 495.16 301.74
## - Spermidine 1 0.765 495.18 301.75
## - X4.Hydroxyphenyllactate 1 0.777 495.19 301.76
## - X3.Hydroxybenzoic.acid 1 0.905 495.32 301.83
## - Iodide 1 0.940 495.35 301.85
## - Salicylic.acid 1 1.146 495.56 301.98
## - Hippuric.acid 1 1.393 495.81 302.12
## - Cre..uM. 1 1.478 495.89 302.17
## - Phenol 1 1.750 496.16 302.33
## - ALB..g.L. 1 2.189 496.60 302.59
## - X4.Hydroxybenzoic.acid.4.O.sulphate 1 2.225 496.64 302.61
## - Urocanic.acid 1 2.354 496.77 302.69
## - Bilirubin...47 1 2.498 496.91 302.77
## - ALP..U.L. 1 2.636 497.05 302.86
## - N8.Acetylspermidine 1 2.717 497.13 302.90
## - Indole.3.methyl.acetate 1 2.814 497.23 302.96
## - Sphinganine.1.phosphate 1 2.892 497.31 303.01
## - Acetylcholine 1 3.115 497.53 303.14
## - TBA..uM. 1 3.220 497.63 303.20
## <none> 494.41 303.30
## - N.Acetylcadaverine 1 3.391 497.80 303.30
## - Homovanillic.acid.sulfate 1 3.496 497.91 303.36
## - Bilirubin...82 1 3.641 498.05 303.45
## - EO.... 1 4.488 498.90 303.94
## - Phenyllactate 1 4.493 498.91 303.95
## - Cinnamoylglycine 1 4.729 499.14 304.09
## - X2.Hydroxy.Hippuric.Acid 1 4.757 499.17 304.10
## - N.acetyl.aspartic.acid 1 5.046 499.46 304.27
## - T.BIL..uM. 1 5.075 499.49 304.29
## - D.BIL..uM. 1 5.317 499.73 304.43
## - Imidazolepropionic.acid 1 5.600 500.01 304.60
## - Indoxyl.sulfate 1 5.660 500.07 304.63
## - Cholesterol.sulfate 1 5.913 500.33 304.78
## - Phenylethylamine 1 6.231 500.64 304.97
## + Phenylacetic.acid 1 0.130 494.28 305.22
## + Υ.GT..U.L. 1 0.127 494.29 305.22
## + Dopa 1 0.118 494.29 305.23
## + UA..uM. 1 0.106 494.31 305.23
## + X4.Hydroxyphenylpropionate 1 0.104 494.31 305.24
## + X3.Hydroxyphenylacetic.acid 1 0.074 494.34 305.25
## + Oleoylethanolamide 1 0.073 494.34 305.25
## + BASO.... 1 0.071 494.34 305.26
## + WBC..10.9.L. 1 0.065 494.35 305.26
## + p.Cresol.glucuronide 1 0.060 494.35 305.26
## + S.gosine.1.phosphate_b 1 0.036 494.38 305.28
## + Dopamine 1 0.033 494.38 305.28
## + X4.Ethylphenyl.sulfate 1 0.029 494.38 305.28
## + LDL.C..mM. 1 0.012 494.40 305.29
## + Urea..mM. 1 0.009 494.40 305.29
## + Biliverdin 1 0.001 494.41 305.30
## + Enterolactone 1 0.000 494.41 305.30
## - Phenylacetylglutamine.PAGln. 1 6.820 501.23 305.31
## - X3.Hydroxyanthranilic.acid 1 8.168 502.58 306.10
## - Xanthurenic.acid 1 8.177 502.59 306.10
## - Octadecanamide 1 8.411 502.82 306.24
## - X3.Hydroxyhippuric.acid 1 8.476 502.89 306.28
## - Kynurenic.acid 1 8.597 503.01 306.35
## - Gamma.aminobutyric.acid 1 8.623 503.04 306.36
## - Oleamide 1 8.646 503.06 306.38
## - Indole.3.carboxaldehyde 1 9.125 503.54 306.66
## - S.ganine.1.phosphate_b 1 10.397 504.81 307.39
## - Ascorbic.acid 1 11.391 505.80 307.97
## - Sphinganine 1 11.671 506.08 308.13
## - LYMPH.... 1 11.751 506.16 308.18
## - NEUT.... 1 12.194 506.61 308.44
## - AST..U.L. 1 14.792 509.21 309.93
## - Phenyl.sulfate 1 16.538 510.95 310.94
## - X5.Aminopentanoic.acid 1 16.755 511.17 311.06
## - Acetylglycine 1 17.021 511.43 311.21
## - Pantothenol 1 18.749 513.16 312.20
## - X3.Hydroxypropionic.acid 1 23.351 517.76 314.82
## - X3..3.Hydroxyphenyl..3.hydroxypropanoic.acid 1 24.651 519.06 315.55
## - ALT..U.L. 1 25.258 519.67 315.90
## - X1.5.Anhydrosorbitol 1 26.929 521.34 316.84
## - HDL.C..mM. 1 27.577 521.99 317.20
## - Indole.3.acrylic.acid 1 39.246 533.66 323.68
## - Palmitoylethanolamide 1 40.655 535.07 324.45
## - X3.Indolebutyric.acid 1 55.413 549.83 332.42
## - TG..mM. 1 80.189 574.60 345.34
##
## Step: AIC=301.4
## FBG..mM. ~ ALT..U.L. + AST..U.L. + Cre..uM. + ALB..g.L. + TG..mM. +
## HDL.C..mM. + ALP..U.L. + T.BIL..uM. + D.BIL..uM. + TBA..uM. +
## CHE..U.L. + NEUT.... + LYMPH.... + EO.... + Phenylethylamine +
## Octadecanamide + Urocanic.acid + Imidazolepropionic.acid +
## Indole.3.carboxaldehyde + X3.Hydroxyanthranilic.acid + Oleamide +
## Palmitic.amide + Palmitoylethanolamide + Stearoylethanolamide +
## Bilirubin...47 + Indole.3.acrylic.acid + Kynurenic.acid +
## Indole.3.propionic.acid + Indole.3.methyl.acetate + Sphinganine +
## Sphinganine.1.phosphate + Sphingosine + X3.Indolebutyric.acid +
## Sphingosine.1.phosphate + X5.Methoxyindoleacetate + Phenylacetylglutamine.PAGln. +
## Pantothenol + Putrescine + Gamma.aminobutyric.acid + X5.Aminopentanoic.acid +
## N.Acetylcadaverine + Acetylcholine + Spermidine + N.acetyl.aspartic.acid +
## N8.Acetylspermidine + Spermine + Phenol + p.Cresol + X1.5.Anhydrosorbitol +
## Benzoic.acid + X3.Hydroxybenzoic.acid + X4.Hydroxybenzoic.acid +
## Salicylic.acid + Phenyllactate + Bilirubin...82 + X3..3.Hydroxyphenyl..3.hydroxypropanoic.acid +
## X4.Hydroxyphenyllactate + p.Cresol.sulfate + X2.Hydroxy.Hippuric.Acid +
## X3.Hydroxyhippuric.acid + S.ganine.1.phosphate_b + Cholesterol.sulfate +
## Xanthurenic.acid + Cinnamoylglycine + Indoxyl.sulfate + Ascorbic.acid +
## Homovanillic.acid.sulfate + Iodide + Phenyl.sulfate + X4.Hydroxybenzoic.acid.4.O.sulphate +
## X3.Hydroxypropionic.acid + Acetylglycine + Hippuric.acid
##
## Df Sum of Sq RSS AIC
## - Sphingosine 1 0.158 494.75 299.50
## - X4.Hydroxybenzoic.acid 1 0.197 494.79 299.52
## - Palmitic.amide 1 0.215 494.80 299.53
## - p.Cresol 1 0.236 494.83 299.54
## - Putrescine 1 0.262 494.85 299.56
## - Benzoic.acid 1 0.343 494.93 299.60
## - CHE..U.L. 1 0.379 494.97 299.63
## - p.Cresol.sulfate 1 0.432 495.02 299.66
## - Stearoylethanolamide 1 0.500 495.09 299.70
## - Sphingosine.1.phosphate 1 0.620 495.21 299.77
## - Indole.3.propionic.acid 1 0.623 495.21 299.77
## - Spermine 1 0.640 495.23 299.78
## - X5.Methoxyindoleacetate 1 0.741 495.33 299.84
## - X4.Hydroxyphenyllactate 1 0.762 495.35 299.85
## - Spermidine 1 0.793 495.38 299.87
## - X3.Hydroxybenzoic.acid 1 0.853 495.44 299.91
## - Iodide 1 0.890 495.48 299.93
## - Salicylic.acid 1 1.125 495.71 300.07
## - Hippuric.acid 1 1.426 496.02 300.25
## - Cre..uM. 1 1.543 496.13 300.31
## - Phenol 1 1.745 496.33 300.43
## - X4.Hydroxybenzoic.acid.4.O.sulphate 1 2.211 496.80 300.71
## - ALB..g.L. 1 2.212 496.80 300.71
## - Urocanic.acid 1 2.368 496.96 300.80
## - Bilirubin...47 1 2.477 497.07 300.87
## - ALP..U.L. 1 2.517 497.11 300.89
## - N8.Acetylspermidine 1 2.697 497.29 300.99
## - Indole.3.methyl.acetate 1 2.827 497.42 301.07
## - Sphinganine.1.phosphate 1 2.856 497.45 301.09
## - TBA..uM. 1 3.270 497.86 301.33
## - Acetylcholine 1 3.281 497.87 301.34
## - N.Acetylcadaverine 1 3.384 497.97 301.40
## <none> 494.59 301.40
## - Homovanillic.acid.sulfate 1 3.513 498.10 301.48
## - Bilirubin...82 1 3.615 498.20 301.54
## - EO.... 1 4.432 499.02 302.02
## - Phenyllactate 1 4.553 499.14 302.09
## - X2.Hydroxy.Hippuric.Acid 1 4.886 499.47 302.28
## - Cinnamoylglycine 1 4.966 499.56 302.33
## - N.acetyl.aspartic.acid 1 5.176 499.77 302.45
## - T.BIL..uM. 1 5.449 500.04 302.61
## - Indoxyl.sulfate 1 5.616 500.21 302.71
## - Imidazolepropionic.acid 1 5.665 500.25 302.74
## - D.BIL..uM. 1 5.800 500.39 302.82
## - Cholesterol.sulfate 1 5.967 500.56 302.92
## - Phenylethylamine 1 6.246 500.84 303.08
## + TC..mM. 1 0.177 494.41 303.30
## + Phenylacetic.acid 1 0.158 494.43 303.31
## + Υ.GT..U.L. 1 0.128 494.46 303.33
## + Dopa 1 0.111 494.48 303.34
## + X4.Hydroxyphenylpropionate 1 0.100 494.49 303.34
## + Oleoylethanolamide 1 0.097 494.49 303.34
## + UA..uM. 1 0.081 494.51 303.35
## + WBC..10.9.L. 1 0.070 494.52 303.36
## + BASO.... 1 0.057 494.53 303.37
## + X3.Hydroxyphenylacetic.acid 1 0.056 494.53 303.37
## + p.Cresol.glucuronide 1 0.052 494.54 303.37
## + S.gosine.1.phosphate_b 1 0.035 494.55 303.38
## + X4.Ethylphenyl.sulfate 1 0.034 494.56 303.38
## + Dopamine 1 0.020 494.57 303.39
## + Urea..mM. 1 0.018 494.57 303.39
## + Biliverdin 1 0.006 494.58 303.40
## + LDL.C..mM. 1 0.001 494.59 303.40
## + Enterolactone 1 0.000 494.59 303.40
## - Phenylacetylglutamine.PAGln. 1 6.828 501.42 303.42
## - X3.Hydroxyanthranilic.acid 1 8.062 502.65 304.14
## - Xanthurenic.acid 1 8.130 502.72 304.18
## - X3.Hydroxyhippuric.acid 1 8.348 502.94 304.31
## - Kynurenic.acid 1 8.499 503.09 304.39
## - Gamma.aminobutyric.acid 1 8.529 503.12 304.41
## - Octadecanamide 1 8.596 503.18 304.45
## - Oleamide 1 8.751 503.34 304.54
## - Indole.3.carboxaldehyde 1 9.400 503.99 304.92
## - S.ganine.1.phosphate_b 1 10.249 504.84 305.41
## - Ascorbic.acid 1 11.411 506.00 306.08
## - Sphinganine 1 11.502 506.09 306.14
## - LYMPH.... 1 11.678 506.27 306.24
## - NEUT.... 1 12.099 506.69 306.48
## - AST..U.L. 1 14.621 509.21 307.94
## - Phenyl.sulfate 1 16.543 511.13 309.04
## - X5.Aminopentanoic.acid 1 17.304 511.89 309.48
## - Acetylglycine 1 17.588 512.18 309.64
## - Pantothenol 1 19.124 513.71 310.52
## - X3.Hydroxypropionic.acid 1 23.273 517.86 312.87
## - X3..3.Hydroxyphenyl..3.hydroxypropanoic.acid 1 24.544 519.13 313.59
## - ALT..U.L. 1 25.193 519.78 313.96
## - X1.5.Anhydrosorbitol 1 27.196 521.78 315.09
## - HDL.C..mM. 1 27.637 522.23 315.33
## - Indole.3.acrylic.acid 1 39.443 534.03 321.88
## - Palmitoylethanolamide 1 40.582 535.17 322.51
## - X3.Indolebutyric.acid 1 55.256 549.85 330.43
## - TG..mM. 1 80.103 574.69 343.38
##
## Step: AIC=299.5
## FBG..mM. ~ ALT..U.L. + AST..U.L. + Cre..uM. + ALB..g.L. + TG..mM. +
## HDL.C..mM. + ALP..U.L. + T.BIL..uM. + D.BIL..uM. + TBA..uM. +
## CHE..U.L. + NEUT.... + LYMPH.... + EO.... + Phenylethylamine +
## Octadecanamide + Urocanic.acid + Imidazolepropionic.acid +
## Indole.3.carboxaldehyde + X3.Hydroxyanthranilic.acid + Oleamide +
## Palmitic.amide + Palmitoylethanolamide + Stearoylethanolamide +
## Bilirubin...47 + Indole.3.acrylic.acid + Kynurenic.acid +
## Indole.3.propionic.acid + Indole.3.methyl.acetate + Sphinganine +
## Sphinganine.1.phosphate + X3.Indolebutyric.acid + Sphingosine.1.phosphate +
## X5.Methoxyindoleacetate + Phenylacetylglutamine.PAGln. +
## Pantothenol + Putrescine + Gamma.aminobutyric.acid + X5.Aminopentanoic.acid +
## N.Acetylcadaverine + Acetylcholine + Spermidine + N.acetyl.aspartic.acid +
## N8.Acetylspermidine + Spermine + Phenol + p.Cresol + X1.5.Anhydrosorbitol +
## Benzoic.acid + X3.Hydroxybenzoic.acid + X4.Hydroxybenzoic.acid +
## Salicylic.acid + Phenyllactate + Bilirubin...82 + X3..3.Hydroxyphenyl..3.hydroxypropanoic.acid +
## X4.Hydroxyphenyllactate + p.Cresol.sulfate + X2.Hydroxy.Hippuric.Acid +
## X3.Hydroxyhippuric.acid + S.ganine.1.phosphate_b + Cholesterol.sulfate +
## Xanthurenic.acid + Cinnamoylglycine + Indoxyl.sulfate + Ascorbic.acid +
## Homovanillic.acid.sulfate + Iodide + Phenyl.sulfate + X4.Hydroxybenzoic.acid.4.O.sulphate +
## X3.Hydroxypropionic.acid + Acetylglycine + Hippuric.acid
##
## Df Sum of Sq RSS AIC
## - X4.Hydroxybenzoic.acid 1 0.169 494.92 297.60
## - p.Cresol 1 0.196 494.94 297.61
## - Palmitic.amide 1 0.254 495.00 297.65
## - Putrescine 1 0.258 495.00 297.65
## - Benzoic.acid 1 0.397 495.14 297.73
## - CHE..U.L. 1 0.404 495.15 297.73
## - p.Cresol.sulfate 1 0.478 495.22 297.78
## - Sphingosine.1.phosphate 1 0.508 495.26 297.80
## - Stearoylethanolamide 1 0.523 495.27 297.80
## - Indole.3.propionic.acid 1 0.664 495.41 297.89
## - Spermine 1 0.715 495.46 297.92
## - X5.Methoxyindoleacetate 1 0.753 495.50 297.94
## - X4.Hydroxyphenyllactate 1 0.820 495.57 297.98
## - Spermidine 1 0.847 495.59 298.00
## - Iodide 1 0.876 495.62 298.01
## - X3.Hydroxybenzoic.acid 1 0.942 495.69 298.05
## - Salicylic.acid 1 1.060 495.81 298.12
## - Hippuric.acid 1 1.430 496.18 298.34
## - Cre..uM. 1 1.453 496.20 298.35
## - Phenol 1 1.745 496.49 298.53
## - ALB..g.L. 1 2.188 496.93 298.79
## - X4.Hydroxybenzoic.acid.4.O.sulphate 1 2.228 496.97 298.81
## - Urocanic.acid 1 2.315 497.06 298.86
## - ALP..U.L. 1 2.400 497.15 298.91
## - Bilirubin...47 1 2.466 497.21 298.95
## - N8.Acetylspermidine 1 2.622 497.37 299.04
## - Sphinganine.1.phosphate 1 2.765 497.51 299.13
## - Indole.3.methyl.acetate 1 2.938 497.69 299.23
## - TBA..uM. 1 3.327 498.07 299.46
## - Acetylcholine 1 3.344 498.09 299.47
## <none> 494.75 299.50
## - N.Acetylcadaverine 1 3.458 498.21 299.54
## - Bilirubin...82 1 3.610 498.36 299.63
## - Homovanillic.acid.sulfate 1 3.617 498.36 299.63
## - Phenyllactate 1 4.527 499.27 300.16
## - EO.... 1 4.532 499.28 300.17
## - X2.Hydroxy.Hippuric.Acid 1 4.794 499.54 300.32
## - Cinnamoylglycine 1 4.929 499.68 300.40
## - N.acetyl.aspartic.acid 1 5.028 499.78 300.46
## - T.BIL..uM. 1 5.308 500.05 300.62
## - D.BIL..uM. 1 5.652 500.40 300.82
## - Indoxyl.sulfate 1 5.790 500.54 300.90
## - Imidazolepropionic.acid 1 5.901 500.65 300.97
## - Cholesterol.sulfate 1 6.015 500.76 301.04
## - Phenylethylamine 1 6.093 500.84 301.08
## + Phenylacetic.acid 1 0.183 494.56 301.39
## + Sphingosine 1 0.158 494.59 301.40
## + TC..mM. 1 0.149 494.60 301.41
## + Υ.GT..U.L. 1 0.124 494.62 301.42
## + Oleoylethanolamide 1 0.119 494.63 301.42
## + Dopa 1 0.106 494.64 301.43
## + UA..uM. 1 0.100 494.65 301.44
## + p.Cresol.glucuronide 1 0.082 494.67 301.45
## + X4.Hydroxyphenylpropionate 1 0.063 494.68 301.46
## + WBC..10.9.L. 1 0.058 494.69 301.46
## + X3.Hydroxyphenylacetic.acid 1 0.051 494.70 301.47
## - Phenylacetylglutamine.PAGln. 1 6.758 501.51 301.47
## + BASO.... 1 0.040 494.71 301.47
## + X4.Ethylphenyl.sulfate 1 0.039 494.71 301.47
## + S.gosine.1.phosphate_b 1 0.019 494.73 301.48
## + Dopamine 1 0.015 494.73 301.49
## + Urea..mM. 1 0.007 494.74 301.49
## + Biliverdin 1 0.006 494.74 301.49
## + LDL.C..mM. 1 0.001 494.75 301.49
## + Enterolactone 1 0.000 494.75 301.50
## - X3.Hydroxyanthranilic.acid 1 7.950 502.70 302.17
## - Xanthurenic.acid 1 8.077 502.82 302.24
## - X3.Hydroxyhippuric.acid 1 8.371 503.12 302.41
## - Gamma.aminobutyric.acid 1 8.372 503.12 302.41
## - Kynurenic.acid 1 8.515 503.26 302.50
## - Octadecanamide 1 8.841 503.59 302.68
## - Oleamide 1 8.893 503.64 302.71
## - Indole.3.carboxaldehyde 1 9.326 504.07 302.97
## - S.ganine.1.phosphate_b 1 10.220 504.97 303.49
## - Ascorbic.acid 1 11.356 506.10 304.14
## - LYMPH.... 1 11.520 506.27 304.24
## - NEUT.... 1 11.952 506.70 304.49
## - AST..U.L. 1 14.479 509.23 305.95
## - Phenyl.sulfate 1 16.487 511.23 307.10
## - Acetylglycine 1 17.451 512.20 307.65
## - X5.Aminopentanoic.acid 1 17.784 512.53 307.84
## - Pantothenol 1 19.280 514.03 308.70
## - X3.Hydroxypropionic.acid 1 23.152 517.90 310.89
## - X3..3.Hydroxyphenyl..3.hydroxypropanoic.acid 1 24.815 519.56 311.83
## - ALT..U.L. 1 25.430 520.18 312.18
## - Sphinganine 1 26.639 521.39 312.86
## - X1.5.Anhydrosorbitol 1 27.215 521.96 313.18
## - HDL.C..mM. 1 28.938 523.69 314.15
## - Indole.3.acrylic.acid 1 40.280 535.03 320.43
## - Palmitoylethanolamide 1 40.766 535.51 320.69
## - X3.Indolebutyric.acid 1 55.201 549.95 328.49
## - TG..mM. 1 80.547 575.29 341.69
##
## Step: AIC=297.6
## FBG..mM. ~ ALT..U.L. + AST..U.L. + Cre..uM. + ALB..g.L. + TG..mM. +
## HDL.C..mM. + ALP..U.L. + T.BIL..uM. + D.BIL..uM. + TBA..uM. +
## CHE..U.L. + NEUT.... + LYMPH.... + EO.... + Phenylethylamine +
## Octadecanamide + Urocanic.acid + Imidazolepropionic.acid +
## Indole.3.carboxaldehyde + X3.Hydroxyanthranilic.acid + Oleamide +
## Palmitic.amide + Palmitoylethanolamide + Stearoylethanolamide +
## Bilirubin...47 + Indole.3.acrylic.acid + Kynurenic.acid +
## Indole.3.propionic.acid + Indole.3.methyl.acetate + Sphinganine +
## Sphinganine.1.phosphate + X3.Indolebutyric.acid + Sphingosine.1.phosphate +
## X5.Methoxyindoleacetate + Phenylacetylglutamine.PAGln. +
## Pantothenol + Putrescine + Gamma.aminobutyric.acid + X5.Aminopentanoic.acid +
## N.Acetylcadaverine + Acetylcholine + Spermidine + N.acetyl.aspartic.acid +
## N8.Acetylspermidine + Spermine + Phenol + p.Cresol + X1.5.Anhydrosorbitol +
## Benzoic.acid + X3.Hydroxybenzoic.acid + Salicylic.acid +
## Phenyllactate + Bilirubin...82 + X3..3.Hydroxyphenyl..3.hydroxypropanoic.acid +
## X4.Hydroxyphenyllactate + p.Cresol.sulfate + X2.Hydroxy.Hippuric.Acid +
## X3.Hydroxyhippuric.acid + S.ganine.1.phosphate_b + Cholesterol.sulfate +
## Xanthurenic.acid + Cinnamoylglycine + Indoxyl.sulfate + Ascorbic.acid +
## Homovanillic.acid.sulfate + Iodide + Phenyl.sulfate + X4.Hydroxybenzoic.acid.4.O.sulphate +
## X3.Hydroxypropionic.acid + Acetylglycine + Hippuric.acid
##
## Df Sum of Sq RSS AIC
## - p.Cresol 1 0.201 495.12 295.71
## - Palmitic.amide 1 0.224 495.14 295.73
## - Putrescine 1 0.259 495.17 295.75
## - Benzoic.acid 1 0.358 495.27 295.81
## - p.Cresol.sulfate 1 0.454 495.37 295.86
## - Sphingosine.1.phosphate 1 0.473 495.39 295.87
## - CHE..U.L. 1 0.487 495.40 295.88
## - Stearoylethanolamide 1 0.522 495.44 295.90
## - Indole.3.propionic.acid 1 0.670 495.59 295.99
## - Spermine 1 0.692 495.61 296.00
## - X5.Methoxyindoleacetate 1 0.724 495.64 296.02
## - X4.Hydroxyphenyllactate 1 0.803 495.72 296.07
## - Iodide 1 0.919 495.84 296.14
## - Spermidine 1 0.941 495.86 296.15
## - X3.Hydroxybenzoic.acid 1 0.964 495.88 296.17
## - Hippuric.acid 1 1.489 496.41 296.48
## - Cre..uM. 1 1.630 496.55 296.56
## - Phenol 1 1.709 496.63 296.61
## - X4.Hydroxybenzoic.acid.4.O.sulphate 1 2.229 497.15 296.91
## - ALB..g.L. 1 2.247 497.16 296.92
## - ALP..U.L. 1 2.304 497.22 296.96
## - Urocanic.acid 1 2.349 497.27 296.98
## - N8.Acetylspermidine 1 2.562 497.48 297.11
## - Bilirubin...47 1 2.612 497.53 297.14
## - Sphinganine.1.phosphate 1 2.827 497.74 297.26
## - Indole.3.methyl.acetate 1 2.954 497.87 297.34
## - Acetylcholine 1 3.322 498.24 297.56
## - N.Acetylcadaverine 1 3.351 498.27 297.57
## - TBA..uM. 1 3.351 498.27 297.57
## <none> 494.92 297.60
## - Homovanillic.acid.sulfate 1 3.783 498.70 297.83
## - Bilirubin...82 1 3.794 498.71 297.83
## - EO.... 1 4.374 499.29 298.17
## - Phenyllactate 1 4.618 499.53 298.32
## - X2.Hydroxy.Hippuric.Acid 1 4.738 499.65 298.39
## - Cinnamoylglycine 1 4.857 499.77 298.46
## - N.acetyl.aspartic.acid 1 5.188 500.10 298.65
## - T.BIL..uM. 1 5.337 500.25 298.74
## - D.BIL..uM. 1 5.675 500.59 298.94
## - Imidazolepropionic.acid 1 5.826 500.74 299.02
## - Indoxyl.sulfate 1 5.830 500.75 299.03
## - Phenylethylamine 1 5.971 500.89 299.11
## - Cholesterol.sulfate 1 6.121 501.04 299.20
## + X4.Hydroxybenzoic.acid 1 0.169 494.75 299.50
## + Phenylacetic.acid 1 0.161 494.76 299.50
## - Phenylacetylglutamine.PAGln. 1 6.648 501.56 299.50
## + TC..mM. 1 0.137 494.78 299.51
## + Sphingosine 1 0.130 494.79 299.52
## + Dopa 1 0.127 494.79 299.52
## + Υ.GT..U.L. 1 0.113 494.80 299.53
## + Oleoylethanolamide 1 0.106 494.81 299.53
## + UA..uM. 1 0.099 494.82 299.54
## + p.Cresol.glucuronide 1 0.088 494.83 299.54
## + WBC..10.9.L. 1 0.075 494.84 299.55
## + X4.Hydroxyphenylpropionate 1 0.059 494.86 299.56
## + X3.Hydroxyphenylacetic.acid 1 0.057 494.86 299.56
## + X4.Ethylphenyl.sulfate 1 0.053 494.86 299.56
## + S.gosine.1.phosphate_b 1 0.033 494.88 299.58
## + BASO.... 1 0.029 494.89 299.58
## + Dopamine 1 0.010 494.91 299.59
## + Urea..mM. 1 0.008 494.91 299.59
## + Biliverdin 1 0.006 494.91 299.59
## + LDL.C..mM. 1 0.002 494.91 299.59
## + Enterolactone 1 0.000 494.92 299.59
## - Salicylic.acid 1 7.147 502.06 299.80
## - X3.Hydroxyanthranilic.acid 1 7.838 502.75 300.20
## - Xanthurenic.acid 1 7.908 502.82 300.24
## - X3.Hydroxyhippuric.acid 1 8.278 503.19 300.46
## - Kynurenic.acid 1 8.356 503.27 300.50
## - Gamma.aminobutyric.acid 1 8.527 503.44 300.60
## - Octadecanamide 1 8.936 503.85 300.84
## - Indole.3.carboxaldehyde 1 9.165 504.08 300.97
## - Oleamide 1 9.281 504.20 301.04
## - S.ganine.1.phosphate_b 1 10.304 505.22 301.63
## - LYMPH.... 1 11.433 506.35 302.29
## - NEUT.... 1 11.967 506.88 302.60
## - Ascorbic.acid 1 13.286 508.20 303.36
## - AST..U.L. 1 14.340 509.26 303.96
## - Phenyl.sulfate 1 16.501 511.42 305.20
## - X5.Aminopentanoic.acid 1 17.831 512.75 305.97
## - Acetylglycine 1 18.143 513.06 306.14
## - Pantothenol 1 19.214 514.13 306.75
## - X3.Hydroxypropionic.acid 1 22.983 517.90 308.90
## - X3..3.Hydroxyphenyl..3.hydroxypropanoic.acid 1 24.787 519.70 309.91
## - ALT..U.L. 1 25.318 520.23 310.21
## - Sphinganine 1 26.685 521.60 310.98
## - X1.5.Anhydrosorbitol 1 27.155 522.07 311.25
## - HDL.C..mM. 1 28.797 523.71 312.17
## - Indole.3.acrylic.acid 1 40.370 535.29 318.57
## - Palmitoylethanolamide 1 40.778 535.69 318.79
## - X3.Indolebutyric.acid 1 55.055 549.97 326.50
## - TG..mM. 1 81.026 575.94 340.02
##
## Step: AIC=295.71
## FBG..mM. ~ ALT..U.L. + AST..U.L. + Cre..uM. + ALB..g.L. + TG..mM. +
## HDL.C..mM. + ALP..U.L. + T.BIL..uM. + D.BIL..uM. + TBA..uM. +
## CHE..U.L. + NEUT.... + LYMPH.... + EO.... + Phenylethylamine +
## Octadecanamide + Urocanic.acid + Imidazolepropionic.acid +
## Indole.3.carboxaldehyde + X3.Hydroxyanthranilic.acid + Oleamide +
## Palmitic.amide + Palmitoylethanolamide + Stearoylethanolamide +
## Bilirubin...47 + Indole.3.acrylic.acid + Kynurenic.acid +
## Indole.3.propionic.acid + Indole.3.methyl.acetate + Sphinganine +
## Sphinganine.1.phosphate + X3.Indolebutyric.acid + Sphingosine.1.phosphate +
## X5.Methoxyindoleacetate + Phenylacetylglutamine.PAGln. +
## Pantothenol + Putrescine + Gamma.aminobutyric.acid + X5.Aminopentanoic.acid +
## N.Acetylcadaverine + Acetylcholine + Spermidine + N.acetyl.aspartic.acid +
## N8.Acetylspermidine + Spermine + Phenol + X1.5.Anhydrosorbitol +
## Benzoic.acid + X3.Hydroxybenzoic.acid + Salicylic.acid +
## Phenyllactate + Bilirubin...82 + X3..3.Hydroxyphenyl..3.hydroxypropanoic.acid +
## X4.Hydroxyphenyllactate + p.Cresol.sulfate + X2.Hydroxy.Hippuric.Acid +
## X3.Hydroxyhippuric.acid + S.ganine.1.phosphate_b + Cholesterol.sulfate +
## Xanthurenic.acid + Cinnamoylglycine + Indoxyl.sulfate + Ascorbic.acid +
## Homovanillic.acid.sulfate + Iodide + Phenyl.sulfate + X4.Hydroxybenzoic.acid.4.O.sulphate +
## X3.Hydroxypropionic.acid + Acetylglycine + Hippuric.acid
##
## Df Sum of Sq RSS AIC
## - Palmitic.amide 1 0.225 495.34 293.85
## - Putrescine 1 0.318 495.44 293.90
## - Benzoic.acid 1 0.390 495.51 293.95
## - Sphingosine.1.phosphate 1 0.467 495.59 293.99
## - Stearoylethanolamide 1 0.534 495.65 294.03
## - CHE..U.L. 1 0.615 495.73 294.08
## - Indole.3.propionic.acid 1 0.648 495.77 294.10
## - Spermine 1 0.712 495.83 294.14
## - X5.Methoxyindoleacetate 1 0.814 495.93 294.20
## - Spermidine 1 0.915 496.03 294.26
## - Iodide 1 0.935 496.05 294.27
## - X3.Hydroxybenzoic.acid 1 0.997 496.11 294.30
## - X4.Hydroxyphenyllactate 1 1.010 496.13 294.31
## - Hippuric.acid 1 1.360 496.48 294.52
## - Cre..uM. 1 1.640 496.76 294.68
## - Phenol 1 1.842 496.96 294.80
## - X4.Hydroxybenzoic.acid.4.O.sulphate 1 2.033 497.15 294.92
## - ALB..g.L. 1 2.183 497.30 295.00
## - ALP..U.L. 1 2.283 497.40 295.06
## - Urocanic.acid 1 2.373 497.49 295.12
## - N8.Acetylspermidine 1 2.416 497.53 295.14
## - Bilirubin...47 1 2.670 497.79 295.29
## - Sphinganine.1.phosphate 1 2.702 497.82 295.31
## - Indole.3.methyl.acetate 1 2.915 498.03 295.43
## <none> 495.12 295.71
## - TBA..uM. 1 3.418 498.54 295.73
## - N.Acetylcadaverine 1 3.496 498.61 295.78
## - Homovanillic.acid.sulfate 1 3.700 498.82 295.90
## - Acetylcholine 1 3.731 498.85 295.91
## - Bilirubin...82 1 3.920 499.04 296.03
## - EO.... 1 4.380 499.50 296.30
## - Cinnamoylglycine 1 4.742 499.86 296.51
## - X2.Hydroxy.Hippuric.Acid 1 4.869 499.99 296.58
## - N.acetyl.aspartic.acid 1 5.180 500.30 296.76
## - Phenyllactate 1 5.279 500.40 296.82
## - T.BIL..uM. 1 5.535 500.65 296.97
## - Imidazolepropionic.acid 1 5.693 500.81 297.06
## - Indoxyl.sulfate 1 5.759 500.88 297.10
## - D.BIL..uM. 1 5.864 500.98 297.16
## - Phenylethylamine 1 5.875 500.99 297.17
## - Phenylacetylglutamine.PAGln. 1 6.472 501.59 297.52
## + p.Cresol 1 0.201 494.92 297.60
## + X4.Hydroxybenzoic.acid 1 0.175 494.94 297.61
## + TC..mM. 1 0.134 494.98 297.64
## + Υ.GT..U.L. 1 0.131 494.99 297.64
## + Phenylacetic.acid 1 0.127 494.99 297.64
## + UA..uM. 1 0.111 495.01 297.65
## + Dopa 1 0.106 495.01 297.65
## + Sphingosine 1 0.093 495.02 297.66
## + X4.Hydroxyphenylpropionate 1 0.080 495.04 297.67
## + X3.Hydroxyphenylacetic.acid 1 0.079 495.04 297.67
## + Oleoylethanolamide 1 0.077 495.04 297.67
## + WBC..10.9.L. 1 0.065 495.05 297.68
## + p.Cresol.glucuronide 1 0.043 495.08 297.69
## + BASO.... 1 0.040 495.08 297.69
## + S.gosine.1.phosphate_b 1 0.034 495.08 297.69
## + X4.Ethylphenyl.sulfate 1 0.028 495.09 297.70
## + Biliverdin 1 0.009 495.11 297.71
## + Dopamine 1 0.008 495.11 297.71
## + Urea..mM. 1 0.004 495.11 297.71
## + Enterolactone 1 0.003 495.11 297.71
## + LDL.C..mM. 1 0.000 495.12 297.71
## - Cholesterol.sulfate 1 6.903 502.02 297.77
## - Salicylic.acid 1 7.316 502.43 298.01
## - Xanthurenic.acid 1 7.832 502.95 298.31
## - X3.Hydroxyanthranilic.acid 1 8.085 503.20 298.46
## - X3.Hydroxyhippuric.acid 1 8.110 503.23 298.47
## - Gamma.aminobutyric.acid 1 8.409 503.53 298.65
## - p.Cresol.sulfate 1 8.497 503.61 298.70
## - Kynurenic.acid 1 8.652 503.77 298.79
## - Indole.3.carboxaldehyde 1 9.101 504.22 299.05
## - Octadecanamide 1 9.139 504.26 299.07
## - Oleamide 1 9.209 504.33 299.11
## - S.ganine.1.phosphate_b 1 10.195 505.31 299.69
## - LYMPH.... 1 11.327 506.44 300.34
## - NEUT.... 1 11.873 506.99 300.66
## - Ascorbic.acid 1 13.154 508.27 301.40
## - AST..U.L. 1 14.403 509.52 302.12
## - Phenyl.sulfate 1 16.962 512.08 303.58
## - X5.Aminopentanoic.acid 1 17.781 512.90 304.05
## - Acetylglycine 1 18.256 513.37 304.32
## - Pantothenol 1 19.238 514.36 304.88
## - X3.Hydroxypropionic.acid 1 22.816 517.93 306.91
## - X3..3.Hydroxyphenyl..3.hydroxypropanoic.acid 1 24.593 519.71 307.92
## - ALT..U.L. 1 25.138 520.26 308.23
## - X1.5.Anhydrosorbitol 1 27.054 522.17 309.30
## - Sphinganine 1 27.259 522.38 309.42
## - HDL.C..mM. 1 29.447 524.56 310.64
## - Indole.3.acrylic.acid 1 40.784 535.90 316.91
## - Palmitoylethanolamide 1 41.090 536.21 317.07
## - X3.Indolebutyric.acid 1 54.915 550.03 324.53
## - TG..mM. 1 81.283 576.40 338.25
##
## Step: AIC=293.85
## FBG..mM. ~ ALT..U.L. + AST..U.L. + Cre..uM. + ALB..g.L. + TG..mM. +
## HDL.C..mM. + ALP..U.L. + T.BIL..uM. + D.BIL..uM. + TBA..uM. +
## CHE..U.L. + NEUT.... + LYMPH.... + EO.... + Phenylethylamine +
## Octadecanamide + Urocanic.acid + Imidazolepropionic.acid +
## Indole.3.carboxaldehyde + X3.Hydroxyanthranilic.acid + Oleamide +
## Palmitoylethanolamide + Stearoylethanolamide + Bilirubin...47 +
## Indole.3.acrylic.acid + Kynurenic.acid + Indole.3.propionic.acid +
## Indole.3.methyl.acetate + Sphinganine + Sphinganine.1.phosphate +
## X3.Indolebutyric.acid + Sphingosine.1.phosphate + X5.Methoxyindoleacetate +
## Phenylacetylglutamine.PAGln. + Pantothenol + Putrescine +
## Gamma.aminobutyric.acid + X5.Aminopentanoic.acid + N.Acetylcadaverine +
## Acetylcholine + Spermidine + N.acetyl.aspartic.acid + N8.Acetylspermidine +
## Spermine + Phenol + X1.5.Anhydrosorbitol + Benzoic.acid +
## X3.Hydroxybenzoic.acid + Salicylic.acid + Phenyllactate +
## Bilirubin...82 + X3..3.Hydroxyphenyl..3.hydroxypropanoic.acid +
## X4.Hydroxyphenyllactate + p.Cresol.sulfate + X2.Hydroxy.Hippuric.Acid +
## X3.Hydroxyhippuric.acid + S.ganine.1.phosphate_b + Cholesterol.sulfate +
## Xanthurenic.acid + Cinnamoylglycine + Indoxyl.sulfate + Ascorbic.acid +
## Homovanillic.acid.sulfate + Iodide + Phenyl.sulfate + X4.Hydroxybenzoic.acid.4.O.sulphate +
## X3.Hydroxypropionic.acid + Acetylglycine + Hippuric.acid
##
## Df Sum of Sq RSS AIC
## - Putrescine 1 0.261 495.60 292.00
## - Benzoic.acid 1 0.380 495.72 292.07
## - Sphingosine.1.phosphate 1 0.532 495.87 292.16
## - Stearoylethanolamide 1 0.547 495.89 292.17
## - CHE..U.L. 1 0.569 495.91 292.18
## - Indole.3.propionic.acid 1 0.614 495.96 292.21
## - Spermine 1 0.684 496.03 292.25
## - X5.Methoxyindoleacetate 1 0.821 496.16 292.33
## - Iodide 1 0.883 496.23 292.37
## - X4.Hydroxyphenyllactate 1 0.949 496.29 292.41
## - Spermidine 1 0.979 496.32 292.43
## - X3.Hydroxybenzoic.acid 1 0.986 496.33 292.43
## - Hippuric.acid 1 1.321 496.66 292.63
## - Cre..uM. 1 1.723 497.07 292.86
## - Phenol 1 1.818 497.16 292.92
## - X4.Hydroxybenzoic.acid.4.O.sulphate 1 1.951 497.29 293.00
## - ALP..U.L. 1 2.249 497.59 293.17
## - ALB..g.L. 1 2.378 497.72 293.25
## - Sphinganine.1.phosphate 1 2.508 497.85 293.33
## - N8.Acetylspermidine 1 2.512 497.85 293.33
## - Urocanic.acid 1 2.584 497.93 293.37
## - Bilirubin...47 1 2.829 498.17 293.52
## - Indole.3.methyl.acetate 1 2.871 498.21 293.54
## - TBA..uM. 1 3.340 498.68 293.82
## <none> 495.34 293.85
## - N.Acetylcadaverine 1 3.421 498.76 293.86
## - Acetylcholine 1 3.685 499.03 294.02
## - Homovanillic.acid.sulfate 1 3.771 499.11 294.07
## - Bilirubin...82 1 4.207 499.55 294.33
## - EO.... 1 4.346 499.69 294.41
## - Cinnamoylglycine 1 4.673 500.02 294.60
## - X2.Hydroxy.Hippuric.Acid 1 5.058 500.40 294.82
## - N.acetyl.aspartic.acid 1 5.110 500.45 294.85
## - Phenyllactate 1 5.141 500.48 294.87
## - T.BIL..uM. 1 5.661 501.00 295.18
## - Indoxyl.sulfate 1 5.771 501.11 295.24
## - Phenylethylamine 1 5.866 501.21 295.30
## - Imidazolepropionic.acid 1 5.973 501.32 295.36
## - D.BIL..uM. 1 6.017 501.36 295.39
## - Phenylacetylglutamine.PAGln. 1 6.297 501.64 295.55
## + Palmitic.amide 1 0.225 495.12 295.71
## + p.Cresol 1 0.203 495.14 295.73
## + Υ.GT..U.L. 1 0.168 495.17 295.75
## + X4.Hydroxybenzoic.acid 1 0.144 495.20 295.76
## + Sphingosine 1 0.124 495.22 295.77
## + TC..mM. 1 0.120 495.22 295.78
## + Phenylacetic.acid 1 0.110 495.23 295.78
## + X3.Hydroxyphenylacetic.acid 1 0.096 495.25 295.79
## + UA..uM. 1 0.094 495.25 295.79
## + X4.Hydroxyphenylpropionate 1 0.091 495.25 295.79
## + Oleoylethanolamide 1 0.087 495.26 295.80
## + WBC..10.9.L. 1 0.069 495.27 295.81
## + Dopa 1 0.065 495.28 295.81
## + BASO.... 1 0.065 495.28 295.81
## + p.Cresol.glucuronide 1 0.054 495.29 295.82
## + X4.Ethylphenyl.sulfate 1 0.023 495.32 295.83
## + S.gosine.1.phosphate_b 1 0.023 495.32 295.83
## + Dopamine 1 0.019 495.32 295.84
## + Biliverdin 1 0.010 495.33 295.84
## + Urea..mM. 1 0.006 495.34 295.84
## + Enterolactone 1 0.001 495.34 295.85
## + LDL.C..mM. 1 0.000 495.34 295.85
## - Cholesterol.sulfate 1 6.832 502.17 295.86
## - Salicylic.acid 1 7.497 502.84 296.25
## - Xanthurenic.acid 1 7.752 503.09 296.40
## - X3.Hydroxyanthranilic.acid 1 7.981 503.32 296.53
## - X3.Hydroxyhippuric.acid 1 8.114 503.46 296.61
## - p.Cresol.sulfate 1 8.320 503.66 296.73
## - Gamma.aminobutyric.acid 1 8.366 503.71 296.75
## - Kynurenic.acid 1 8.599 503.94 296.89
## - Octadecanamide 1 9.019 504.36 297.13
## - Indole.3.carboxaldehyde 1 9.200 504.54 297.24
## - S.ganine.1.phosphate_b 1 9.983 505.33 297.69
## - Oleamide 1 10.942 506.28 298.25
## - LYMPH.... 1 11.309 506.65 298.46
## - NEUT.... 1 12.037 507.38 298.88
## - Ascorbic.acid 1 13.392 508.73 299.66
## - AST..U.L. 1 14.285 509.63 300.18
## - Phenyl.sulfate 1 16.815 512.16 301.63
## - Acetylglycine 1 18.200 513.54 302.42
## - Pantothenol 1 19.596 514.94 303.22
## - X5.Aminopentanoic.acid 1 20.092 515.43 303.50
## - X3.Hydroxypropionic.acid 1 22.627 517.97 304.94
## - X3..3.Hydroxyphenyl..3.hydroxypropanoic.acid 1 24.369 519.71 305.92
## - ALT..U.L. 1 25.295 520.64 306.44
## - X1.5.Anhydrosorbitol 1 27.216 522.56 307.52
## - Sphinganine 1 28.520 523.86 308.25
## - HDL.C..mM. 1 29.515 524.86 308.81
## - Palmitoylethanolamide 1 40.866 536.21 315.07
## - Indole.3.acrylic.acid 1 42.024 537.37 315.71
## - X3.Indolebutyric.acid 1 54.695 550.04 322.54
## - TG..mM. 1 81.062 576.40 336.25
##
## Step: AIC=292
## FBG..mM. ~ ALT..U.L. + AST..U.L. + Cre..uM. + ALB..g.L. + TG..mM. +
## HDL.C..mM. + ALP..U.L. + T.BIL..uM. + D.BIL..uM. + TBA..uM. +
## CHE..U.L. + NEUT.... + LYMPH.... + EO.... + Phenylethylamine +
## Octadecanamide + Urocanic.acid + Imidazolepropionic.acid +
## Indole.3.carboxaldehyde + X3.Hydroxyanthranilic.acid + Oleamide +
## Palmitoylethanolamide + Stearoylethanolamide + Bilirubin...47 +
## Indole.3.acrylic.acid + Kynurenic.acid + Indole.3.propionic.acid +
## Indole.3.methyl.acetate + Sphinganine + Sphinganine.1.phosphate +
## X3.Indolebutyric.acid + Sphingosine.1.phosphate + X5.Methoxyindoleacetate +
## Phenylacetylglutamine.PAGln. + Pantothenol + Gamma.aminobutyric.acid +
## X5.Aminopentanoic.acid + N.Acetylcadaverine + Acetylcholine +
## Spermidine + N.acetyl.aspartic.acid + N8.Acetylspermidine +
## Spermine + Phenol + X1.5.Anhydrosorbitol + Benzoic.acid +
## X3.Hydroxybenzoic.acid + Salicylic.acid + Phenyllactate +
## Bilirubin...82 + X3..3.Hydroxyphenyl..3.hydroxypropanoic.acid +
## X4.Hydroxyphenyllactate + p.Cresol.sulfate + X2.Hydroxy.Hippuric.Acid +
## X3.Hydroxyhippuric.acid + S.ganine.1.phosphate_b + Cholesterol.sulfate +
## Xanthurenic.acid + Cinnamoylglycine + Indoxyl.sulfate + Ascorbic.acid +
## Homovanillic.acid.sulfate + Iodide + Phenyl.sulfate + X4.Hydroxybenzoic.acid.4.O.sulphate +
## X3.Hydroxypropionic.acid + Acetylglycine + Hippuric.acid
##
## Df Sum of Sq RSS AIC
## - Benzoic.acid 1 0.324 495.93 290.19
## - Stearoylethanolamide 1 0.519 496.12 290.31
## - Indole.3.propionic.acid 1 0.597 496.20 290.35
## - CHE..U.L. 1 0.622 496.23 290.37
## - X5.Methoxyindoleacetate 1 0.708 496.31 290.42
## - Spermine 1 0.712 496.32 290.42
## - Sphingosine.1.phosphate 1 0.753 496.36 290.45
## - Iodide 1 0.943 496.55 290.56
## - X4.Hydroxyphenyllactate 1 0.995 496.60 290.59
## - Spermidine 1 1.009 496.61 290.60
## - X3.Hydroxybenzoic.acid 1 1.049 496.65 290.62
## - Hippuric.acid 1 1.221 496.82 290.72
## - Cre..uM. 1 1.581 497.18 290.94
## - X4.Hydroxybenzoic.acid.4.O.sulphate 1 1.769 497.37 291.05
## - Phenol 1 1.876 497.48 291.11
## - ALB..g.L. 1 2.388 497.99 291.41
## - ALP..U.L. 1 2.451 498.05 291.45
## - Sphinganine.1.phosphate 1 2.581 498.18 291.52
## - Urocanic.acid 1 2.594 498.20 291.53
## - N8.Acetylspermidine 1 2.759 498.36 291.63
## - Indole.3.methyl.acetate 1 2.816 498.42 291.66
## - Bilirubin...47 1 3.105 498.71 291.83
## - TBA..uM. 1 3.290 498.89 291.94
## - N.Acetylcadaverine 1 3.319 498.92 291.96
## <none> 495.60 292.00
## - Acetylcholine 1 3.439 499.04 292.03
## - Homovanillic.acid.sulfate 1 3.938 499.54 292.32
## - EO.... 1 4.202 499.81 292.48
## - Bilirubin...82 1 4.316 499.92 292.54
## - Cinnamoylglycine 1 4.706 500.31 292.77
## - N.acetyl.aspartic.acid 1 4.859 500.46 292.86
## - Phenyllactate 1 5.116 500.72 293.01
## - X2.Hydroxy.Hippuric.Acid 1 5.135 500.74 293.02
## - T.BIL..uM. 1 5.778 501.38 293.40
## - Phenylethylamine 1 5.988 501.59 293.52
## - Indoxyl.sulfate 1 6.182 501.79 293.63
## - D.BIL..uM. 1 6.311 501.91 293.71
## - Phenylacetylglutamine.PAGln. 1 6.480 502.08 293.81
## - Imidazolepropionic.acid 1 6.546 502.15 293.85
## + Putrescine 1 0.261 495.34 293.85
## + p.Cresol 1 0.256 495.35 293.85
## + Υ.GT..U.L. 1 0.187 495.42 293.89
## + Palmitic.amide 1 0.168 495.44 293.90
## + X4.Hydroxybenzoic.acid 1 0.149 495.45 293.91
## + Phenylacetic.acid 1 0.130 495.47 293.93
## + TC..mM. 1 0.125 495.48 293.93
## + Oleoylethanolamide 1 0.122 495.48 293.93
## + Sphingosine 1 0.111 495.49 293.94
## + S.gosine.1.phosphate_b 1 0.111 495.49 293.94
## + UA..uM. 1 0.109 495.49 293.94
## + Dopa 1 0.090 495.51 293.95
## + X3.Hydroxyphenylacetic.acid 1 0.079 495.52 293.96
## + X4.Hydroxyphenylpropionate 1 0.074 495.53 293.96
## + BASO.... 1 0.059 495.54 293.97
## + Dopamine 1 0.055 495.55 293.97
## + WBC..10.9.L. 1 0.041 495.56 293.98
## + p.Cresol.glucuronide 1 0.032 495.57 293.98
## + X4.Ethylphenyl.sulfate 1 0.024 495.58 293.99
## + Biliverdin 1 0.011 495.59 294.00
## + Urea..mM. 1 0.008 495.60 294.00
## + LDL.C..mM. 1 0.000 495.60 294.00
## + Enterolactone 1 0.000 495.60 294.00
## - Cholesterol.sulfate 1 6.888 502.49 294.05
## - Salicylic.acid 1 7.585 503.19 294.45
## - X3.Hydroxyanthranilic.acid 1 7.820 503.42 294.59
## - Xanthurenic.acid 1 7.931 503.53 294.65
## - X3.Hydroxyhippuric.acid 1 8.260 503.86 294.84
## - p.Cresol.sulfate 1 8.461 504.07 294.96
## - Kynurenic.acid 1 8.551 504.15 295.01
## - Gamma.aminobutyric.acid 1 8.656 504.26 295.08
## - Octadecanamide 1 8.948 504.55 295.24
## - Indole.3.carboxaldehyde 1 9.910 505.51 295.80
## - S.ganine.1.phosphate_b 1 10.266 505.87 296.01
## - Oleamide 1 10.757 506.36 296.29
## - LYMPH.... 1 11.175 506.78 296.54
## - NEUT.... 1 11.923 507.53 296.97
## - Ascorbic.acid 1 13.222 508.83 297.72
## - AST..U.L. 1 14.230 509.83 298.30
## - Phenyl.sulfate 1 16.566 512.17 299.64
## - Acetylglycine 1 18.760 514.36 300.89
## - Pantothenol 1 19.458 515.06 301.29
## - X5.Aminopentanoic.acid 1 20.721 516.33 302.00
## - X3.Hydroxypropionic.acid 1 22.478 518.08 303.00
## - X3..3.Hydroxyphenyl..3.hydroxypropanoic.acid 1 24.674 520.28 304.24
## - ALT..U.L. 1 25.226 520.83 304.55
## - X1.5.Anhydrosorbitol 1 27.377 522.98 305.76
## - Sphinganine 1 28.325 523.93 306.29
## - HDL.C..mM. 1 29.365 524.97 306.87
## - Palmitoylethanolamide 1 41.081 536.68 313.33
## - Indole.3.acrylic.acid 1 41.807 537.41 313.73
## - X3.Indolebutyric.acid 1 54.470 550.07 320.56
## - TG..mM. 1 81.128 576.73 334.42
##
## Step: AIC=290.19
## FBG..mM. ~ ALT..U.L. + AST..U.L. + Cre..uM. + ALB..g.L. + TG..mM. +
## HDL.C..mM. + ALP..U.L. + T.BIL..uM. + D.BIL..uM. + TBA..uM. +
## CHE..U.L. + NEUT.... + LYMPH.... + EO.... + Phenylethylamine +
## Octadecanamide + Urocanic.acid + Imidazolepropionic.acid +
## Indole.3.carboxaldehyde + X3.Hydroxyanthranilic.acid + Oleamide +
## Palmitoylethanolamide + Stearoylethanolamide + Bilirubin...47 +
## Indole.3.acrylic.acid + Kynurenic.acid + Indole.3.propionic.acid +
## Indole.3.methyl.acetate + Sphinganine + Sphinganine.1.phosphate +
## X3.Indolebutyric.acid + Sphingosine.1.phosphate + X5.Methoxyindoleacetate +
## Phenylacetylglutamine.PAGln. + Pantothenol + Gamma.aminobutyric.acid +
## X5.Aminopentanoic.acid + N.Acetylcadaverine + Acetylcholine +
## Spermidine + N.acetyl.aspartic.acid + N8.Acetylspermidine +
## Spermine + Phenol + X1.5.Anhydrosorbitol + X3.Hydroxybenzoic.acid +
## Salicylic.acid + Phenyllactate + Bilirubin...82 + X3..3.Hydroxyphenyl..3.hydroxypropanoic.acid +
## X4.Hydroxyphenyllactate + p.Cresol.sulfate + X2.Hydroxy.Hippuric.Acid +
## X3.Hydroxyhippuric.acid + S.ganine.1.phosphate_b + Cholesterol.sulfate +
## Xanthurenic.acid + Cinnamoylglycine + Indoxyl.sulfate + Ascorbic.acid +
## Homovanillic.acid.sulfate + Iodide + Phenyl.sulfate + X4.Hydroxybenzoic.acid.4.O.sulphate +
## X3.Hydroxypropionic.acid + Acetylglycine + Hippuric.acid
##
## Df Sum of Sq RSS AIC
## - Stearoylethanolamide 1 0.424 496.35 288.44
## - Indole.3.propionic.acid 1 0.562 496.49 288.53
## - CHE..U.L. 1 0.613 496.54 288.56
## - Sphingosine.1.phosphate 1 0.641 496.57 288.57
## - Spermine 1 0.697 496.62 288.60
## - X5.Methoxyindoleacetate 1 0.699 496.63 288.61
## - Iodide 1 0.933 496.86 288.74
## - X4.Hydroxyphenyllactate 1 0.962 496.89 288.76
## - Spermidine 1 1.127 497.05 288.86
## - X3.Hydroxybenzoic.acid 1 1.192 497.12 288.90
## - Hippuric.acid 1 1.215 497.14 288.91
## - Cre..uM. 1 1.555 497.48 289.11
## - X4.Hydroxybenzoic.acid.4.O.sulphate 1 1.736 497.66 289.22
## - Phenol 1 1.810 497.74 289.26
## - ALP..U.L. 1 2.355 498.28 289.58
## - ALB..g.L. 1 2.411 498.34 289.61
## - Urocanic.acid 1 2.433 498.36 289.63
## - Sphinganine.1.phosphate 1 2.585 498.51 289.72
## - Indole.3.methyl.acetate 1 2.722 498.65 289.80
## - N8.Acetylspermidine 1 2.873 498.80 289.89
## - Bilirubin...47 1 2.893 498.82 289.90
## - TBA..uM. 1 3.163 499.09 290.06
## - N.Acetylcadaverine 1 3.260 499.19 290.11
## <none> 495.93 290.19
## - Acetylcholine 1 3.510 499.44 290.26
## - Bilirubin...82 1 4.055 499.98 290.58
## - Homovanillic.acid.sulfate 1 4.271 500.20 290.71
## - EO.... 1 4.293 500.22 290.72
## - Cinnamoylglycine 1 4.504 500.43 290.84
## - X2.Hydroxy.Hippuric.Acid 1 4.936 500.86 291.10
## - N.acetyl.aspartic.acid 1 4.997 500.92 291.13
## - Phenyllactate 1 5.205 501.13 291.25
## - T.BIL..uM. 1 5.625 501.55 291.50
## - Phenylethylamine 1 5.975 501.90 291.70
## - D.BIL..uM. 1 6.138 502.07 291.80
## - Indoxyl.sulfate 1 6.222 502.15 291.85
## - Imidazolepropionic.acid 1 6.367 502.29 291.93
## + Benzoic.acid 1 0.324 495.60 292.00
## - Phenylacetylglutamine.PAGln. 1 6.512 502.44 292.02
## + p.Cresol 1 0.282 495.65 292.03
## + Putrescine 1 0.205 495.72 292.07
## + TC..mM. 1 0.167 495.76 292.09
## + Palmitic.amide 1 0.166 495.76 292.10
## + UA..uM. 1 0.156 495.77 292.10
## + Υ.GT..U.L. 1 0.154 495.77 292.10
## + Sphingosine 1 0.153 495.77 292.10
## + Dopa 1 0.117 495.81 292.12
## + X4.Hydroxybenzoic.acid 1 0.114 495.81 292.13
## + Phenylacetic.acid 1 0.107 495.82 292.13
## + X3.Hydroxyphenylacetic.acid 1 0.101 495.83 292.13
## + Oleoylethanolamide 1 0.083 495.84 292.14
## + S.gosine.1.phosphate_b 1 0.064 495.86 292.16
## + Dopamine 1 0.062 495.87 292.16
## + X4.Hydroxyphenylpropionate 1 0.061 495.87 292.16
## + BASO.... 1 0.046 495.88 292.17
## - Cholesterol.sulfate 1 6.779 502.71 292.17
## + WBC..10.9.L. 1 0.032 495.90 292.17
## + Biliverdin 1 0.026 495.90 292.18
## + p.Cresol.glucuronide 1 0.020 495.91 292.18
## + Urea..mM. 1 0.011 495.92 292.19
## + X4.Ethylphenyl.sulfate 1 0.005 495.92 292.19
## + Enterolactone 1 0.003 495.93 292.19
## + LDL.C..mM. 1 0.001 495.93 292.19
## - Salicylic.acid 1 7.359 503.29 292.51
## - Xanthurenic.acid 1 7.769 503.70 292.75
## - X3.Hydroxyanthranilic.acid 1 8.184 504.11 292.99
## - X3.Hydroxyhippuric.acid 1 8.443 504.37 293.14
## - p.Cresol.sulfate 1 8.613 504.54 293.24
## - Gamma.aminobutyric.acid 1 8.785 504.71 293.34
## - Kynurenic.acid 1 8.910 504.84 293.41
## - Octadecanamide 1 9.001 504.93 293.46
## - Indole.3.carboxaldehyde 1 9.925 505.85 294.00
## - S.ganine.1.phosphate_b 1 10.190 506.12 294.15
## - Oleamide 1 10.949 506.88 294.59
## - LYMPH.... 1 11.352 507.28 294.82
## - NEUT.... 1 12.041 507.97 295.22
## - Ascorbic.acid 1 13.297 509.22 295.95
## - AST..U.L. 1 14.542 510.47 296.66
## - Phenyl.sulfate 1 16.784 512.71 297.95
## - Acetylglycine 1 18.843 514.77 299.12
## - Pantothenol 1 19.190 515.12 299.32
## - X5.Aminopentanoic.acid 1 20.559 516.49 300.09
## - X3.Hydroxypropionic.acid 1 22.353 518.28 301.11
## - X3..3.Hydroxyphenyl..3.hydroxypropanoic.acid 1 24.808 520.74 302.50
## - ALT..U.L. 1 25.401 521.33 302.83
## - X1.5.Anhydrosorbitol 1 27.337 523.26 303.91
## - Sphinganine 1 28.246 524.17 304.42
## - HDL.C..mM. 1 29.744 525.67 305.26
## - Palmitoylethanolamide 1 40.765 536.69 311.34
## - Indole.3.acrylic.acid 1 41.511 537.44 311.75
## - X3.Indolebutyric.acid 1 54.694 550.62 318.85
## - TG..mM. 1 82.091 578.02 333.07
##
## Step: AIC=288.44
## FBG..mM. ~ ALT..U.L. + AST..U.L. + Cre..uM. + ALB..g.L. + TG..mM. +
## HDL.C..mM. + ALP..U.L. + T.BIL..uM. + D.BIL..uM. + TBA..uM. +
## CHE..U.L. + NEUT.... + LYMPH.... + EO.... + Phenylethylamine +
## Octadecanamide + Urocanic.acid + Imidazolepropionic.acid +
## Indole.3.carboxaldehyde + X3.Hydroxyanthranilic.acid + Oleamide +
## Palmitoylethanolamide + Bilirubin...47 + Indole.3.acrylic.acid +
## Kynurenic.acid + Indole.3.propionic.acid + Indole.3.methyl.acetate +
## Sphinganine + Sphinganine.1.phosphate + X3.Indolebutyric.acid +
## Sphingosine.1.phosphate + X5.Methoxyindoleacetate + Phenylacetylglutamine.PAGln. +
## Pantothenol + Gamma.aminobutyric.acid + X5.Aminopentanoic.acid +
## N.Acetylcadaverine + Acetylcholine + Spermidine + N.acetyl.aspartic.acid +
## N8.Acetylspermidine + Spermine + Phenol + X1.5.Anhydrosorbitol +
## X3.Hydroxybenzoic.acid + Salicylic.acid + Phenyllactate +
## Bilirubin...82 + X3..3.Hydroxyphenyl..3.hydroxypropanoic.acid +
## X4.Hydroxyphenyllactate + p.Cresol.sulfate + X2.Hydroxy.Hippuric.Acid +
## X3.Hydroxyhippuric.acid + S.ganine.1.phosphate_b + Cholesterol.sulfate +
## Xanthurenic.acid + Cinnamoylglycine + Indoxyl.sulfate + Ascorbic.acid +
## Homovanillic.acid.sulfate + Iodide + Phenyl.sulfate + X4.Hydroxybenzoic.acid.4.O.sulphate +
## X3.Hydroxypropionic.acid + Acetylglycine + Hippuric.acid
##
## Df Sum of Sq RSS AIC
## - X5.Methoxyindoleacetate 1 0.487 496.84 286.73
## - Indole.3.propionic.acid 1 0.603 496.95 286.80
## - Sphingosine.1.phosphate 1 0.615 496.97 286.81
## - CHE..U.L. 1 0.615 496.97 286.81
## - Spermine 1 0.721 497.07 286.87
## - Spermidine 1 0.951 497.30 287.00
## - Iodide 1 0.975 497.33 287.02
## - Hippuric.acid 1 1.186 497.54 287.14
## - X4.Hydroxyphenyllactate 1 1.227 497.58 287.17
## - X3.Hydroxybenzoic.acid 1 1.324 497.67 287.22
## - Cre..uM. 1 1.429 497.78 287.29
## - Phenol 1 1.845 498.20 287.53
## - X4.Hydroxybenzoic.acid.4.O.sulphate 1 2.013 498.36 287.63
## - ALP..U.L. 1 2.365 498.72 287.84
## - Urocanic.acid 1 2.424 498.78 287.87
## - Sphinganine.1.phosphate 1 2.630 498.98 287.99
## - ALB..g.L. 1 2.774 499.13 288.08
## - Indole.3.methyl.acetate 1 2.788 499.14 288.08
## - TBA..uM. 1 2.972 499.32 288.19
## - Bilirubin...47 1 2.974 499.33 288.19
## - N8.Acetylspermidine 1 3.003 499.35 288.21
## - N.Acetylcadaverine 1 3.212 499.56 288.33
## - Acetylcholine 1 3.306 499.66 288.39
## <none> 496.35 288.44
## - EO.... 1 4.051 500.40 288.83
## - Homovanillic.acid.sulfate 1 4.193 500.54 288.91
## - Bilirubin...82 1 4.213 500.56 288.92
## - Cinnamoylglycine 1 4.551 500.90 289.12
## - N.acetyl.aspartic.acid 1 4.733 501.08 289.22
## - X2.Hydroxy.Hippuric.Acid 1 5.262 501.61 289.53
## - Phenyllactate 1 5.809 502.16 289.85
## - Imidazolepropionic.acid 1 5.962 502.31 289.94
## - T.BIL..uM. 1 6.328 502.68 290.16
## - Phenylethylamine 1 6.370 502.72 290.18
## + Stearoylethanolamide 1 0.424 495.93 290.19
## + p.Cresol 1 0.288 496.06 290.27
## + Benzoic.acid 1 0.229 496.12 290.31
## + Oleoylethanolamide 1 0.198 496.15 290.33
## + Putrescine 1 0.190 496.16 290.33
## + TC..mM. 1 0.188 496.16 290.33
## + Palmitic.amide 1 0.178 496.17 290.34
## + Sphingosine 1 0.166 496.18 290.35
## + Υ.GT..U.L. 1 0.164 496.19 290.35
## - Indoxyl.sulfate 1 6.667 503.02 290.35
## + UA..uM. 1 0.150 496.20 290.36
## + Dopa 1 0.129 496.22 290.37
## - Phenylacetylglutamine.PAGln. 1 6.696 503.05 290.37
## + X4.Hydroxybenzoic.acid 1 0.118 496.23 290.37
## + Phenylacetic.acid 1 0.103 496.25 290.38
## + X3.Hydroxyphenylacetic.acid 1 0.083 496.27 290.39
## + Dopamine 1 0.078 496.27 290.40
## + Biliverdin 1 0.069 496.28 290.40
## + BASO.... 1 0.058 496.29 290.41
## + X4.Hydroxyphenylpropionate 1 0.055 496.30 290.41
## + S.gosine.1.phosphate_b 1 0.040 496.31 290.42
## + Urea..mM. 1 0.023 496.33 290.43
## + p.Cresol.glucuronide 1 0.022 496.33 290.43
## + X4.Ethylphenyl.sulfate 1 0.017 496.33 290.43
## + WBC..10.9.L. 1 0.011 496.34 290.44
## + LDL.C..mM. 1 0.001 496.35 290.44
## + Enterolactone 1 0.001 496.35 290.44
## - Cholesterol.sulfate 1 6.871 503.22 290.47
## - D.BIL..uM. 1 6.972 503.32 290.53
## - Salicylic.acid 1 7.800 504.15 291.01
## - Xanthurenic.acid 1 7.852 504.20 291.04
## - X3.Hydroxyhippuric.acid 1 8.090 504.44 291.18
## - Gamma.aminobutyric.acid 1 8.547 504.90 291.45
## - p.Cresol.sulfate 1 8.849 505.20 291.62
## - Octadecanamide 1 9.018 505.37 291.72
## - Kynurenic.acid 1 9.527 505.88 292.01
## - S.ganine.1.phosphate_b 1 10.670 507.02 292.68
## - Oleamide 1 10.695 507.05 292.69
## - LYMPH.... 1 11.026 507.38 292.88
## - Indole.3.carboxaldehyde 1 11.081 507.43 292.91
## - NEUT.... 1 11.683 508.03 293.26
## - X3.Hydroxyanthranilic.acid 1 12.863 509.21 293.94
## - Ascorbic.acid 1 13.330 509.68 294.21
## - AST..U.L. 1 15.098 511.45 295.22
## - Phenyl.sulfate 1 16.729 513.08 296.16
## - Pantothenol 1 18.848 515.20 297.36
## - Acetylglycine 1 18.877 515.23 297.38
## - X5.Aminopentanoic.acid 1 20.160 516.51 298.11
## - X3.Hydroxypropionic.acid 1 23.690 520.04 300.10
## - X3..3.Hydroxyphenyl..3.hydroxypropanoic.acid 1 24.393 520.74 300.50
## - ALT..U.L. 1 26.449 522.80 301.66
## - Sphinganine 1 27.879 524.23 302.46
## - X1.5.Anhydrosorbitol 1 28.586 524.94 302.85
## - HDL.C..mM. 1 30.124 526.48 303.71
## - Indole.3.acrylic.acid 1 41.118 537.47 309.76
## - X3.Indolebutyric.acid 1 54.280 550.63 316.85
## - Palmitoylethanolamide 1 57.074 553.43 318.33
## - TG..mM. 1 81.935 578.29 331.21
##
## Step: AIC=286.73
## FBG..mM. ~ ALT..U.L. + AST..U.L. + Cre..uM. + ALB..g.L. + TG..mM. +
## HDL.C..mM. + ALP..U.L. + T.BIL..uM. + D.BIL..uM. + TBA..uM. +
## CHE..U.L. + NEUT.... + LYMPH.... + EO.... + Phenylethylamine +
## Octadecanamide + Urocanic.acid + Imidazolepropionic.acid +
## Indole.3.carboxaldehyde + X3.Hydroxyanthranilic.acid + Oleamide +
## Palmitoylethanolamide + Bilirubin...47 + Indole.3.acrylic.acid +
## Kynurenic.acid + Indole.3.propionic.acid + Indole.3.methyl.acetate +
## Sphinganine + Sphinganine.1.phosphate + X3.Indolebutyric.acid +
## Sphingosine.1.phosphate + Phenylacetylglutamine.PAGln. +
## Pantothenol + Gamma.aminobutyric.acid + X5.Aminopentanoic.acid +
## N.Acetylcadaverine + Acetylcholine + Spermidine + N.acetyl.aspartic.acid +
## N8.Acetylspermidine + Spermine + Phenol + X1.5.Anhydrosorbitol +
## X3.Hydroxybenzoic.acid + Salicylic.acid + Phenyllactate +
## Bilirubin...82 + X3..3.Hydroxyphenyl..3.hydroxypropanoic.acid +
## X4.Hydroxyphenyllactate + p.Cresol.sulfate + X2.Hydroxy.Hippuric.Acid +
## X3.Hydroxyhippuric.acid + S.ganine.1.phosphate_b + Cholesterol.sulfate +
## Xanthurenic.acid + Cinnamoylglycine + Indoxyl.sulfate + Ascorbic.acid +
## Homovanillic.acid.sulfate + Iodide + Phenyl.sulfate + X4.Hydroxybenzoic.acid.4.O.sulphate +
## X3.Hydroxypropionic.acid + Acetylglycine + Hippuric.acid
##
## Df Sum of Sq RSS AIC
## - Sphingosine.1.phosphate 1 0.484 497.32 285.02
## - CHE..U.L. 1 0.619 497.46 285.10
## - Indole.3.propionic.acid 1 0.619 497.46 285.10
## - Spermine 1 0.795 497.63 285.20
## - Spermidine 1 0.854 497.69 285.23
## - Iodide 1 0.883 497.72 285.25
## - X4.Hydroxyphenyllactate 1 1.123 497.96 285.39
## - Cre..uM. 1 1.227 498.07 285.45
## - Hippuric.acid 1 1.356 498.19 285.53
## - X3.Hydroxybenzoic.acid 1 1.377 498.22 285.54
## - Phenol 1 1.987 498.83 285.90
## - X4.Hydroxybenzoic.acid.4.O.sulphate 1 2.255 499.09 286.06
## - Sphinganine.1.phosphate 1 2.481 499.32 286.19
## - Urocanic.acid 1 2.590 499.43 286.25
## - ALP..U.L. 1 2.597 499.44 286.26
## - ALB..g.L. 1 2.772 499.61 286.36
## - Indole.3.methyl.acetate 1 2.827 499.67 286.39
## - TBA..uM. 1 2.966 499.80 286.47
## - Acetylcholine 1 3.032 499.87 286.51
## - N8.Acetylspermidine 1 3.302 500.14 286.67
## - N.Acetylcadaverine 1 3.360 500.20 286.71
## - Bilirubin...47 1 3.362 500.20 286.71
## <none> 496.84 286.73
## - EO.... 1 3.902 500.74 287.02
## - Homovanillic.acid.sulfate 1 4.270 501.11 287.24
## - N.acetyl.aspartic.acid 1 4.486 501.32 287.37
## - Cinnamoylglycine 1 4.807 501.65 287.55
## - Bilirubin...82 1 4.893 501.73 287.60
## - X2.Hydroxy.Hippuric.Acid 1 5.091 501.93 287.72
## - Phenyllactate 1 5.624 502.46 288.03
## - Imidazolepropionic.acid 1 5.654 502.49 288.05
## - T.BIL..uM. 1 6.223 503.06 288.38
## + X5.Methoxyindoleacetate 1 0.487 496.35 288.44
## + p.Cresol 1 0.354 496.48 288.52
## + Oleoylethanolamide 1 0.326 496.51 288.54
## - Phenylacetylglutamine.PAGln. 1 6.511 503.35 288.55
## - Indoxyl.sulfate 1 6.540 503.38 288.56
## + Benzoic.acid 1 0.245 496.59 288.59
## + Stearoylethanolamide 1 0.212 496.63 288.61
## + Palmitic.amide 1 0.190 496.65 288.62
## + TC..mM. 1 0.171 496.67 288.63
## - D.BIL..uM. 1 6.656 503.49 288.63
## + Sphingosine 1 0.170 496.67 288.63
## + Υ.GT..U.L. 1 0.127 496.71 288.66
## + X3.Hydroxyphenylacetic.acid 1 0.125 496.71 288.66
## + UA..uM. 1 0.122 496.72 288.66
## + Putrescine 1 0.112 496.73 288.67
## + X4.Hydroxybenzoic.acid 1 0.096 496.74 288.67
## + Phenylacetic.acid 1 0.093 496.75 288.68
## + Dopamine 1 0.078 496.76 288.69
## + X4.Hydroxyphenylpropionate 1 0.067 496.77 288.69
## + BASO.... 1 0.059 496.78 288.70
## + Dopa 1 0.048 496.79 288.70
## + S.gosine.1.phosphate_b 1 0.037 496.80 288.71
## + Biliverdin 1 0.027 496.81 288.72
## + X4.Ethylphenyl.sulfate 1 0.019 496.82 288.72
## + p.Cresol.glucuronide 1 0.017 496.82 288.72
## + LDL.C..mM. 1 0.013 496.83 288.72
## + WBC..10.9.L. 1 0.012 496.83 288.72
## + Urea..mM. 1 0.006 496.83 288.73
## + Enterolactone 1 0.000 496.84 288.73
## - Phenylethylamine 1 6.851 503.69 288.74
## - Cholesterol.sulfate 1 7.117 503.96 288.90
## - Salicylic.acid 1 7.616 504.45 289.19
## - Octadecanamide 1 8.704 505.54 289.82
## - X3.Hydroxyhippuric.acid 1 8.748 505.59 289.85
## - Xanthurenic.acid 1 8.751 505.59 289.85
## - Gamma.aminobutyric.acid 1 8.830 505.67 289.89
## - p.Cresol.sulfate 1 9.067 505.91 290.03
## - Kynurenic.acid 1 9.543 506.38 290.31
## - S.ganine.1.phosphate_b 1 10.293 507.13 290.74
## - Oleamide 1 10.371 507.21 290.78
## - Indole.3.carboxaldehyde 1 10.853 507.69 291.06
## - LYMPH.... 1 10.891 507.73 291.08
## - NEUT.... 1 11.556 508.40 291.47
## - Ascorbic.acid 1 14.269 511.11 293.03
## - X3.Hydroxyanthranilic.acid 1 14.286 511.12 293.04
## - AST..U.L. 1 15.620 512.46 293.80
## - Phenyl.sulfate 1 16.682 513.52 294.41
## - Pantothenol 1 18.802 515.64 295.61
## - Acetylglycine 1 18.859 515.70 295.65
## - X5.Aminopentanoic.acid 1 19.837 516.68 296.20
## - X3.Hydroxypropionic.acid 1 24.147 520.99 298.64
## - X3..3.Hydroxyphenyl..3.hydroxypropanoic.acid 1 25.024 521.86 299.13
## - Sphinganine 1 27.492 524.33 300.51
## - ALT..U.L. 1 28.638 525.48 301.15
## - X1.5.Anhydrosorbitol 1 29.562 526.40 301.67
## - HDL.C..mM. 1 30.454 527.29 302.16
## - Indole.3.acrylic.acid 1 41.335 538.17 308.15
## - Palmitoylethanolamide 1 57.526 554.36 316.83
## - X3.Indolebutyric.acid 1 57.742 554.58 316.95
## - TG..mM. 1 82.006 578.84 329.49
##
## Step: AIC=285.02
## FBG..mM. ~ ALT..U.L. + AST..U.L. + Cre..uM. + ALB..g.L. + TG..mM. +
## HDL.C..mM. + ALP..U.L. + T.BIL..uM. + D.BIL..uM. + TBA..uM. +
## CHE..U.L. + NEUT.... + LYMPH.... + EO.... + Phenylethylamine +
## Octadecanamide + Urocanic.acid + Imidazolepropionic.acid +
## Indole.3.carboxaldehyde + X3.Hydroxyanthranilic.acid + Oleamide +
## Palmitoylethanolamide + Bilirubin...47 + Indole.3.acrylic.acid +
## Kynurenic.acid + Indole.3.propionic.acid + Indole.3.methyl.acetate +
## Sphinganine + Sphinganine.1.phosphate + X3.Indolebutyric.acid +
## Phenylacetylglutamine.PAGln. + Pantothenol + Gamma.aminobutyric.acid +
## X5.Aminopentanoic.acid + N.Acetylcadaverine + Acetylcholine +
## Spermidine + N.acetyl.aspartic.acid + N8.Acetylspermidine +
## Spermine + Phenol + X1.5.Anhydrosorbitol + X3.Hydroxybenzoic.acid +
## Salicylic.acid + Phenyllactate + Bilirubin...82 + X3..3.Hydroxyphenyl..3.hydroxypropanoic.acid +
## X4.Hydroxyphenyllactate + p.Cresol.sulfate + X2.Hydroxy.Hippuric.Acid +
## X3.Hydroxyhippuric.acid + S.ganine.1.phosphate_b + Cholesterol.sulfate +
## Xanthurenic.acid + Cinnamoylglycine + Indoxyl.sulfate + Ascorbic.acid +
## Homovanillic.acid.sulfate + Iodide + Phenyl.sulfate + X4.Hydroxybenzoic.acid.4.O.sulphate +
## X3.Hydroxypropionic.acid + Acetylglycine + Hippuric.acid
##
## Df Sum of Sq RSS AIC
## - Indole.3.propionic.acid 1 0.490 497.81 283.31
## - CHE..U.L. 1 0.713 498.04 283.44
## - Spermidine 1 0.827 498.15 283.50
## - Spermine 1 0.877 498.20 283.53
## - Iodide 1 0.939 498.26 283.57
## - X4.Hydroxyphenyllactate 1 0.997 498.32 283.60
## - Cre..uM. 1 1.173 498.50 283.71
## - Hippuric.acid 1 1.323 498.65 283.80
## - X3.Hydroxybenzoic.acid 1 1.372 498.70 283.82
## - X4.Hydroxybenzoic.acid.4.O.sulphate 1 2.016 499.34 284.20
## - Phenol 1 2.162 499.48 284.29
## - Urocanic.acid 1 2.338 499.66 284.39
## - ALP..U.L. 1 2.344 499.67 284.39
## - Indole.3.methyl.acetate 1 2.584 499.91 284.54
## - TBA..uM. 1 2.743 500.07 284.63
## - ALB..g.L. 1 2.803 500.13 284.66
## - Acetylcholine 1 2.828 500.15 284.68
## - Sphinganine.1.phosphate 1 2.971 500.29 284.76
## - Bilirubin...47 1 3.292 500.61 284.95
## - N8.Acetylspermidine 1 3.329 500.65 284.97
## - N.Acetylcadaverine 1 3.335 500.66 284.98
## <none> 497.32 285.02
## - EO.... 1 3.689 501.01 285.18
## - Homovanillic.acid.sulfate 1 4.129 501.45 285.44
## - N.acetyl.aspartic.acid 1 4.276 501.60 285.52
## - Cinnamoylglycine 1 4.749 502.07 285.80
## - Bilirubin...82 1 4.860 502.18 285.87
## - X2.Hydroxy.Hippuric.Acid 1 4.927 502.25 285.90
## - Phenyllactate 1 5.587 502.91 286.29
## - T.BIL..uM. 1 5.941 503.26 286.50
## - D.BIL..uM. 1 6.290 503.61 286.70
## + Sphingosine.1.phosphate 1 0.484 496.84 286.73
## + Oleoylethanolamide 1 0.378 496.95 286.79
## + X5.Methoxyindoleacetate 1 0.356 496.97 286.81
## + p.Cresol 1 0.355 496.97 286.81
## + S.gosine.1.phosphate_b 1 0.310 497.01 286.83
## + Putrescine 1 0.252 497.07 286.87
## + Palmitic.amide 1 0.230 497.09 286.88
## + Stearoylethanolamide 1 0.218 497.10 286.89
## - Indoxyl.sulfate 1 6.640 503.96 286.90
## - Phenylacetylglutamine.PAGln. 1 6.643 503.97 286.90
## + X3.Hydroxyphenylacetic.acid 1 0.180 497.14 286.91
## + UA..uM. 1 0.163 497.16 286.92
## + Benzoic.acid 1 0.160 497.16 286.92
## + Υ.GT..U.L. 1 0.159 497.16 286.92
## + TC..mM. 1 0.134 497.19 286.94
## - Imidazolepropionic.acid 1 6.726 504.05 286.95
## + Phenylacetic.acid 1 0.106 497.22 286.95
## + Dopa 1 0.078 497.24 286.97
## + X4.Hydroxyphenylpropionate 1 0.074 497.25 286.97
## + X4.Hydroxybenzoic.acid 1 0.074 497.25 286.97
## + BASO.... 1 0.060 497.26 286.98
## + Dopamine 1 0.054 497.27 286.98
## + Sphingosine 1 0.050 497.27 286.99
## + p.Cresol.glucuronide 1 0.031 497.29 287.00
## + WBC..10.9.L. 1 0.030 497.29 287.00
## + X4.Ethylphenyl.sulfate 1 0.029 497.29 287.00
## + Biliverdin 1 0.016 497.31 287.01
## + Urea..mM. 1 0.010 497.31 287.01
## + LDL.C..mM. 1 0.009 497.31 287.01
## + Enterolactone 1 0.000 497.32 287.02
## - Phenylethylamine 1 7.035 504.36 287.13
## - Cholesterol.sulfate 1 7.082 504.40 287.16
## - Salicylic.acid 1 7.532 504.85 287.42
## - Octadecanamide 1 8.541 505.86 288.01
## - Gamma.aminobutyric.acid 1 8.658 505.98 288.07
## - X3.Hydroxyhippuric.acid 1 8.912 506.23 288.22
## - Kynurenic.acid 1 9.394 506.72 288.50
## - p.Cresol.sulfate 1 9.417 506.74 288.51
## - Xanthurenic.acid 1 9.536 506.86 288.58
## - S.ganine.1.phosphate_b 1 9.834 507.16 288.75
## - Oleamide 1 10.213 507.54 288.97
## - LYMPH.... 1 11.087 508.41 289.48
## - NEUT.... 1 11.641 508.96 289.80
## - Indole.3.carboxaldehyde 1 11.996 509.32 290.00
## - Ascorbic.acid 1 14.101 511.42 291.21
## - X3.Hydroxyanthranilic.acid 1 14.277 511.60 291.31
## - AST..U.L. 1 16.552 513.87 292.61
## - Phenyl.sulfate 1 16.904 514.23 292.81
## - Pantothenol 1 18.557 515.88 293.75
## - Acetylglycine 1 19.072 516.39 294.04
## - X5.Aminopentanoic.acid 1 20.802 518.13 295.02
## - X3.Hydroxypropionic.acid 1 24.834 522.16 297.29
## - X3..3.Hydroxyphenyl..3.hydroxypropanoic.acid 1 25.032 522.36 297.41
## - Sphinganine 1 27.660 524.98 298.88
## - X1.5.Anhydrosorbitol 1 29.337 526.66 299.81
## - ALT..U.L. 1 29.690 527.01 300.01
## - HDL.C..mM. 1 30.411 527.73 300.41
## - Indole.3.acrylic.acid 1 43.274 540.60 307.46
## - Palmitoylethanolamide 1 57.068 554.39 314.85
## - X3.Indolebutyric.acid 1 57.908 555.23 315.29
## - TG..mM. 1 82.027 579.35 327.75
##
## Step: AIC=283.31
## FBG..mM. ~ ALT..U.L. + AST..U.L. + Cre..uM. + ALB..g.L. + TG..mM. +
## HDL.C..mM. + ALP..U.L. + T.BIL..uM. + D.BIL..uM. + TBA..uM. +
## CHE..U.L. + NEUT.... + LYMPH.... + EO.... + Phenylethylamine +
## Octadecanamide + Urocanic.acid + Imidazolepropionic.acid +
## Indole.3.carboxaldehyde + X3.Hydroxyanthranilic.acid + Oleamide +
## Palmitoylethanolamide + Bilirubin...47 + Indole.3.acrylic.acid +
## Kynurenic.acid + Indole.3.methyl.acetate + Sphinganine +
## Sphinganine.1.phosphate + X3.Indolebutyric.acid + Phenylacetylglutamine.PAGln. +
## Pantothenol + Gamma.aminobutyric.acid + X5.Aminopentanoic.acid +
## N.Acetylcadaverine + Acetylcholine + Spermidine + N.acetyl.aspartic.acid +
## N8.Acetylspermidine + Spermine + Phenol + X1.5.Anhydrosorbitol +
## X3.Hydroxybenzoic.acid + Salicylic.acid + Phenyllactate +
## Bilirubin...82 + X3..3.Hydroxyphenyl..3.hydroxypropanoic.acid +
## X4.Hydroxyphenyllactate + p.Cresol.sulfate + X2.Hydroxy.Hippuric.Acid +
## X3.Hydroxyhippuric.acid + S.ganine.1.phosphate_b + Cholesterol.sulfate +
## Xanthurenic.acid + Cinnamoylglycine + Indoxyl.sulfate + Ascorbic.acid +
## Homovanillic.acid.sulfate + Iodide + Phenyl.sulfate + X4.Hydroxybenzoic.acid.4.O.sulphate +
## X3.Hydroxypropionic.acid + Acetylglycine + Hippuric.acid
##
## Df Sum of Sq RSS AIC
## - CHE..U.L. 1 0.646 498.46 281.68
## - Spermidine 1 0.797 498.61 281.77
## - Spermine 1 0.886 498.70 281.83
## - Iodide 1 0.992 498.81 281.89
## - X4.Hydroxyphenyllactate 1 1.023 498.84 281.91
## - Cre..uM. 1 1.165 498.98 281.99
## - Hippuric.acid 1 1.279 499.09 282.06
## - X3.Hydroxybenzoic.acid 1 1.321 499.13 282.08
## - X4.Hydroxybenzoic.acid.4.O.sulphate 1 1.846 499.66 282.39
## - Phenol 1 2.149 499.96 282.57
## - Urocanic.acid 1 2.319 500.13 282.67
## - ALP..U.L. 1 2.339 500.15 282.68
## - TBA..uM. 1 2.679 500.49 282.88
## - Acetylcholine 1 2.853 500.67 282.98
## - Sphinganine.1.phosphate 1 3.010 500.82 283.07
## - ALB..g.L. 1 3.182 501.00 283.17
## - N8.Acetylspermidine 1 3.397 501.21 283.30
## <none> 497.81 283.31
## - EO.... 1 3.530 501.34 283.38
## - Bilirubin...47 1 3.601 501.41 283.42
## - N.Acetylcadaverine 1 3.841 501.65 283.56
## - Homovanillic.acid.sulfate 1 4.055 501.87 283.68
## - N.acetyl.aspartic.acid 1 4.434 502.25 283.90
## - Cinnamoylglycine 1 4.684 502.50 284.05
## - X2.Hydroxy.Hippuric.Acid 1 4.769 502.58 284.10
## - Bilirubin...82 1 5.002 502.82 284.23
## - Phenyllactate 1 5.448 503.26 284.49
## - T.BIL..uM. 1 6.097 503.91 284.87
## + Indole.3.propionic.acid 1 0.490 497.32 285.02
## + Oleoylethanolamide 1 0.387 497.43 285.08
## + X5.Methoxyindoleacetate 1 0.384 497.43 285.08
## - D.BIL..uM. 1 6.480 504.29 285.09
## + Sphingosine.1.phosphate 1 0.355 497.46 285.10
## + p.Cresol 1 0.327 497.49 285.11
## + X3.Hydroxyphenylacetic.acid 1 0.256 497.56 285.15
## + S.gosine.1.phosphate_b 1 0.246 497.57 285.16
## + Stearoylethanolamide 1 0.241 497.57 285.16
## + Putrescine 1 0.214 497.60 285.18
## + Palmitic.amide 1 0.197 497.62 285.19
## + UA..uM. 1 0.187 497.63 285.20
## + X4.Hydroxyphenylpropionate 1 0.183 497.63 285.20
## + Benzoic.acid 1 0.144 497.67 285.22
## + TC..mM. 1 0.139 497.67 285.22
## + Phenylacetic.acid 1 0.116 497.70 285.24
## - Phenylacetylglutamine.PAGln. 1 6.753 504.57 285.25
## + X4.Hydroxybenzoic.acid 1 0.082 497.73 285.26
## + Υ.GT..U.L. 1 0.081 497.73 285.26
## + Sphingosine 1 0.080 497.73 285.26
## + Dopa 1 0.072 497.74 285.26
## + BASO.... 1 0.066 497.75 285.27
## + Dopamine 1 0.065 497.75 285.27
## + p.Cresol.glucuronide 1 0.045 497.77 285.28
## + WBC..10.9.L. 1 0.039 497.77 285.28
## + X4.Ethylphenyl.sulfate 1 0.032 497.78 285.29
## + Biliverdin 1 0.031 497.78 285.29
## + Urea..mM. 1 0.020 497.79 285.29
## + LDL.C..mM. 1 0.008 497.81 285.30
## + Enterolactone 1 0.001 497.81 285.30
## - Imidazolepropionic.acid 1 6.935 504.75 285.36
## - Phenylethylamine 1 6.961 504.77 285.37
## - Cholesterol.sulfate 1 7.025 504.84 285.41
## - Indoxyl.sulfate 1 7.170 504.98 285.50
## - Salicylic.acid 1 7.316 505.13 285.58
## - Octadecanamide 1 8.446 506.26 286.23
## - Gamma.aminobutyric.acid 1 8.844 506.66 286.47
## - X3.Hydroxyhippuric.acid 1 8.905 506.72 286.50
## - Kynurenic.acid 1 9.503 507.32 286.85
## - Xanthurenic.acid 1 9.528 507.34 286.86
## - p.Cresol.sulfate 1 9.623 507.44 286.92
## - S.ganine.1.phosphate_b 1 10.016 507.83 287.14
## - Oleamide 1 10.020 507.83 287.14
## - LYMPH.... 1 10.743 508.56 287.56
## - NEUT.... 1 11.387 509.20 287.93
## - Indole.3.carboxaldehyde 1 12.402 510.21 288.52
## - Ascorbic.acid 1 14.055 511.87 289.46
## - X3.Hydroxyanthranilic.acid 1 14.249 512.06 289.57
## - AST..U.L. 1 16.719 514.53 290.98
## - Phenyl.sulfate 1 16.785 514.60 291.02
## - Pantothenol 1 18.606 516.42 292.06
## - Acetylglycine 1 18.813 516.63 292.17
## - X5.Aminopentanoic.acid 1 21.274 519.09 293.57
## - X3.Hydroxypropionic.acid 1 24.607 522.42 295.44
## - X3..3.Hydroxyphenyl..3.hydroxypropanoic.acid 1 24.948 522.76 295.63
## - Indole.3.methyl.acetate 1 25.480 523.29 295.93
## - Sphinganine 1 27.977 525.79 297.33
## - X1.5.Anhydrosorbitol 1 29.361 527.17 298.10
## - HDL.C..mM. 1 29.949 527.76 298.42
## - ALT..U.L. 1 30.231 528.04 298.58
## - Indole.3.acrylic.acid 1 46.188 544.00 307.30
## - Palmitoylethanolamide 1 56.649 554.46 312.88
## - X3.Indolebutyric.acid 1 57.850 555.66 313.52
## - TG..mM. 1 81.537 579.35 325.75
##
## Step: AIC=281.68
## FBG..mM. ~ ALT..U.L. + AST..U.L. + Cre..uM. + ALB..g.L. + TG..mM. +
## HDL.C..mM. + ALP..U.L. + T.BIL..uM. + D.BIL..uM. + TBA..uM. +
## NEUT.... + LYMPH.... + EO.... + Phenylethylamine + Octadecanamide +
## Urocanic.acid + Imidazolepropionic.acid + Indole.3.carboxaldehyde +
## X3.Hydroxyanthranilic.acid + Oleamide + Palmitoylethanolamide +
## Bilirubin...47 + Indole.3.acrylic.acid + Kynurenic.acid +
## Indole.3.methyl.acetate + Sphinganine + Sphinganine.1.phosphate +
## X3.Indolebutyric.acid + Phenylacetylglutamine.PAGln. + Pantothenol +
## Gamma.aminobutyric.acid + X5.Aminopentanoic.acid + N.Acetylcadaverine +
## Acetylcholine + Spermidine + N.acetyl.aspartic.acid + N8.Acetylspermidine +
## Spermine + Phenol + X1.5.Anhydrosorbitol + X3.Hydroxybenzoic.acid +
## Salicylic.acid + Phenyllactate + Bilirubin...82 + X3..3.Hydroxyphenyl..3.hydroxypropanoic.acid +
## X4.Hydroxyphenyllactate + p.Cresol.sulfate + X2.Hydroxy.Hippuric.Acid +
## X3.Hydroxyhippuric.acid + S.ganine.1.phosphate_b + Cholesterol.sulfate +
## Xanthurenic.acid + Cinnamoylglycine + Indoxyl.sulfate + Ascorbic.acid +
## Homovanillic.acid.sulfate + Iodide + Phenyl.sulfate + X4.Hydroxybenzoic.acid.4.O.sulphate +
## X3.Hydroxypropionic.acid + Acetylglycine + Hippuric.acid
##
## Df Sum of Sq RSS AIC
## - Spermidine 1 0.623 499.08 280.05
## - Iodide 1 1.015 499.47 280.28
## - Cre..uM. 1 1.022 499.48 280.29
## - X3.Hydroxybenzoic.acid 1 1.031 499.49 280.29
## - X4.Hydroxyphenyllactate 1 1.070 499.53 280.31
## - Spermine 1 1.116 499.58 280.34
## - Hippuric.acid 1 1.276 499.73 280.43
## - X4.Hydroxybenzoic.acid.4.O.sulphate 1 1.727 500.19 280.70
## - Phenol 1 2.041 500.50 280.88
## - Urocanic.acid 1 2.340 500.80 281.06
## - TBA..uM. 1 2.546 501.00 281.18
## - Acetylcholine 1 2.566 501.02 281.19
## - ALP..U.L. 1 2.572 501.03 281.19
## - Sphinganine.1.phosphate 1 3.172 501.63 281.54
## <none> 498.46 281.68
## - ALB..g.L. 1 3.433 501.89 281.70
## - EO.... 1 3.634 502.09 281.81
## - N8.Acetylspermidine 1 3.645 502.10 281.82
## - Bilirubin...47 1 3.783 502.24 281.90
## - N.Acetylcadaverine 1 3.998 502.46 282.03
## - Homovanillic.acid.sulfate 1 4.107 502.57 282.09
## - N.acetyl.aspartic.acid 1 4.315 502.77 282.21
## - Cinnamoylglycine 1 4.654 503.11 282.41
## - X2.Hydroxy.Hippuric.Acid 1 4.965 503.42 282.59
## - Bilirubin...82 1 5.082 503.54 282.66
## - Phenyllactate 1 5.759 504.22 283.05
## - T.BIL..uM. 1 5.925 504.38 283.15
## - D.BIL..uM. 1 6.171 504.63 283.29
## + CHE..U.L. 1 0.646 497.81 283.31
## + p.Cresol 1 0.495 497.96 283.39
## - Phenylacetylglutamine.PAGln. 1 6.381 504.84 283.41
## + Sphingosine.1.phosphate 1 0.439 498.02 283.43
## + Indole.3.propionic.acid 1 0.423 498.04 283.44
## + X5.Methoxyindoleacetate 1 0.374 498.08 283.46
## - Cholesterol.sulfate 1 6.483 504.94 283.47
## + Oleoylethanolamide 1 0.340 498.12 283.48
## + X3.Hydroxyphenylacetic.acid 1 0.335 498.12 283.49
## + S.gosine.1.phosphate_b 1 0.327 498.13 283.49
## + Putrescine 1 0.280 498.18 283.52
## + UA..uM. 1 0.253 498.21 283.54
## + Stearoylethanolamide 1 0.241 498.22 283.54
## + X4.Hydroxyphenylpropionate 1 0.165 498.29 283.59
## + X4.Hydroxybenzoic.acid 1 0.158 498.30 283.59
## + TC..mM. 1 0.157 498.30 283.59
## + Palmitic.amide 1 0.152 498.31 283.60
## + Benzoic.acid 1 0.133 498.33 283.61
## + Dopamine 1 0.122 498.34 283.61
## + Phenylacetic.acid 1 0.119 498.34 283.61
## + LDL.C..mM. 1 0.093 498.37 283.63
## + Dopa 1 0.087 498.37 283.63
## + Sphingosine 1 0.072 498.39 283.64
## + WBC..10.9.L. 1 0.065 498.39 283.65
## + BASO.... 1 0.058 498.40 283.65
## + Υ.GT..U.L. 1 0.043 498.42 283.66
## + p.Cresol.glucuronide 1 0.033 498.43 283.67
## + X4.Ethylphenyl.sulfate 1 0.031 498.43 283.67
## + Biliverdin 1 0.020 498.44 283.67
## + Urea..mM. 1 0.016 498.44 283.68
## + Enterolactone 1 0.004 498.45 283.68
## - Indoxyl.sulfate 1 6.878 505.34 283.70
## - Phenylethylamine 1 7.082 505.54 283.82
## - Imidazolepropionic.acid 1 7.204 505.66 283.89
## - Salicylic.acid 1 7.587 506.05 284.11
## - Octadecanamide 1 8.539 507.00 284.66
## - X3.Hydroxyhippuric.acid 1 9.057 507.52 284.96
## - Kynurenic.acid 1 9.214 507.67 285.05
## - Gamma.aminobutyric.acid 1 9.271 507.73 285.08
## - p.Cresol.sulfate 1 9.617 508.08 285.28
## - Oleamide 1 9.774 508.23 285.37
## - Xanthurenic.acid 1 9.960 508.42 285.48
## - LYMPH.... 1 10.260 508.72 285.65
## - S.ganine.1.phosphate_b 1 10.742 509.20 285.93
## - NEUT.... 1 11.127 509.59 286.15
## - Indole.3.carboxaldehyde 1 12.990 511.45 287.22
## - Ascorbic.acid 1 14.459 512.92 288.06
## - X3.Hydroxyanthranilic.acid 1 14.646 513.10 288.17
## - Phenyl.sulfate 1 16.176 514.63 289.04
## - AST..U.L. 1 17.339 515.80 289.70
## - Acetylglycine 1 18.346 516.80 290.28
## - Pantothenol 1 18.361 516.82 290.28
## - X5.Aminopentanoic.acid 1 21.476 519.93 292.04
## - X3..3.Hydroxyphenyl..3.hydroxypropanoic.acid 1 24.793 523.25 293.91
## - Indole.3.methyl.acetate 1 25.726 524.18 294.43
## - X3.Hydroxypropionic.acid 1 25.888 524.35 294.52
## - X1.5.Anhydrosorbitol 1 29.231 527.69 296.38
## - Sphinganine 1 29.560 528.02 296.57
## - HDL.C..mM. 1 29.728 528.19 296.66
## - ALT..U.L. 1 33.447 531.91 298.71
## - Indole.3.acrylic.acid 1 46.530 544.99 305.83
## - Palmitoylethanolamide 1 56.324 554.78 311.05
## - X3.Indolebutyric.acid 1 60.201 558.66 313.09
## - TG..mM. 1 82.948 581.41 324.79
##
## Step: AIC=280.05
## FBG..mM. ~ ALT..U.L. + AST..U.L. + Cre..uM. + ALB..g.L. + TG..mM. +
## HDL.C..mM. + ALP..U.L. + T.BIL..uM. + D.BIL..uM. + TBA..uM. +
## NEUT.... + LYMPH.... + EO.... + Phenylethylamine + Octadecanamide +
## Urocanic.acid + Imidazolepropionic.acid + Indole.3.carboxaldehyde +
## X3.Hydroxyanthranilic.acid + Oleamide + Palmitoylethanolamide +
## Bilirubin...47 + Indole.3.acrylic.acid + Kynurenic.acid +
## Indole.3.methyl.acetate + Sphinganine + Sphinganine.1.phosphate +
## X3.Indolebutyric.acid + Phenylacetylglutamine.PAGln. + Pantothenol +
## Gamma.aminobutyric.acid + X5.Aminopentanoic.acid + N.Acetylcadaverine +
## Acetylcholine + N.acetyl.aspartic.acid + N8.Acetylspermidine +
## Spermine + Phenol + X1.5.Anhydrosorbitol + X3.Hydroxybenzoic.acid +
## Salicylic.acid + Phenyllactate + Bilirubin...82 + X3..3.Hydroxyphenyl..3.hydroxypropanoic.acid +
## X4.Hydroxyphenyllactate + p.Cresol.sulfate + X2.Hydroxy.Hippuric.Acid +
## X3.Hydroxyhippuric.acid + S.ganine.1.phosphate_b + Cholesterol.sulfate +
## Xanthurenic.acid + Cinnamoylglycine + Indoxyl.sulfate + Ascorbic.acid +
## Homovanillic.acid.sulfate + Iodide + Phenyl.sulfate + X4.Hydroxybenzoic.acid.4.O.sulphate +
## X3.Hydroxypropionic.acid + Acetylglycine + Hippuric.acid
##
## Df Sum of Sq RSS AIC
## - Cre..uM. 1 0.966 500.05 278.62
## - Iodide 1 0.973 500.06 278.62
## - X3.Hydroxybenzoic.acid 1 1.111 500.19 278.70
## - Hippuric.acid 1 1.162 500.24 278.73
## - X4.Hydroxyphenyllactate 1 1.269 500.35 278.80
## - X4.Hydroxybenzoic.acid.4.O.sulphate 1 1.557 500.64 278.96
## - Spermine 1 2.012 501.09 279.23
## - Acetylcholine 1 2.250 501.33 279.37
## - Phenol 1 2.259 501.34 279.37
## - Urocanic.acid 1 2.288 501.37 279.39
## - TBA..uM. 1 2.352 501.43 279.43
## - ALP..U.L. 1 2.524 501.61 279.53
## - Sphinganine.1.phosphate 1 2.919 502.00 279.76
## <none> 499.08 280.05
## - ALB..g.L. 1 3.527 502.61 280.11
## - EO.... 1 3.656 502.74 280.19
## - Homovanillic.acid.sulfate 1 3.846 502.93 280.30
## - N8.Acetylspermidine 1 3.853 502.93 280.30
## - Bilirubin...47 1 4.065 503.15 280.43
## - N.acetyl.aspartic.acid 1 4.096 503.18 280.45
## - N.Acetylcadaverine 1 4.537 503.62 280.70
## - Bilirubin...82 1 4.698 503.78 280.80
## - Cinnamoylglycine 1 4.989 504.07 280.97
## - X2.Hydroxy.Hippuric.Acid 1 5.261 504.34 281.12
## - Phenyllactate 1 5.648 504.73 281.35
## + Spermidine 1 0.623 498.46 281.68
## - Phenylacetylglutamine.PAGln. 1 6.314 505.40 281.73
## + CHE..U.L. 1 0.472 498.61 281.77
## + p.Cresol 1 0.433 498.65 281.80
## - Cholesterol.sulfate 1 6.441 505.52 281.81
## + Sphingosine.1.phosphate 1 0.408 498.67 281.81
## + Indole.3.propionic.acid 1 0.407 498.68 281.81
## + X3.Hydroxyphenylacetic.acid 1 0.394 498.69 281.82
## - T.BIL..uM. 1 6.515 505.60 281.85
## + Oleoylethanolamide 1 0.306 498.78 281.87
## + X5.Methoxyindoleacetate 1 0.305 498.78 281.87
## + Putrescine 1 0.294 498.79 281.88
## + S.gosine.1.phosphate_b 1 0.257 498.82 281.90
## + X4.Hydroxybenzoic.acid 1 0.211 498.87 281.93
## + UA..uM. 1 0.207 498.88 281.93
## + Benzoic.acid 1 0.207 498.88 281.93
## + Palmitic.amide 1 0.195 498.89 281.94
## + X4.Hydroxyphenylpropionate 1 0.187 498.89 281.94
## + TC..mM. 1 0.176 498.91 281.95
## + Dopa 1 0.151 498.93 281.96
## + Stearoylethanolamide 1 0.148 498.93 281.96
## + Dopamine 1 0.125 498.96 281.98
## + LDL.C..mM. 1 0.116 498.97 281.98
## + Phenylacetic.acid 1 0.109 498.97 281.99
## + Sphingosine 1 0.109 498.97 281.99
## + Biliverdin 1 0.095 498.99 282.00
## + WBC..10.9.L. 1 0.075 499.01 282.01
## + BASO.... 1 0.067 499.02 282.01
## + X4.Ethylphenyl.sulfate 1 0.033 499.05 282.03
## + Υ.GT..U.L. 1 0.021 499.06 282.04
## + Enterolactone 1 0.010 499.07 282.05
## + p.Cresol.glucuronide 1 0.005 499.08 282.05
## + Urea..mM. 1 0.002 499.08 282.05
## - Indoxyl.sulfate 1 7.004 506.09 282.13
## - Imidazolepropionic.acid 1 7.156 506.24 282.22
## - Phenylethylamine 1 7.320 506.40 282.32
## - D.BIL..uM. 1 7.389 506.47 282.36
## - Salicylic.acid 1 7.893 506.97 282.65
## - Octadecanamide 1 8.015 507.10 282.72
## - X3.Hydroxyhippuric.acid 1 8.821 507.90 283.18
## - Oleamide 1 9.172 508.25 283.39
## - Xanthurenic.acid 1 9.591 508.67 283.63
## - Gamma.aminobutyric.acid 1 9.809 508.89 283.75
## - Kynurenic.acid 1 9.865 508.95 283.79
## - p.Cresol.sulfate 1 9.930 509.01 283.82
## - LYMPH.... 1 9.966 509.05 283.84
## - S.ganine.1.phosphate_b 1 10.358 509.44 284.07
## - NEUT.... 1 10.766 509.85 284.30
## - Indole.3.carboxaldehyde 1 13.327 512.41 285.77
## - Ascorbic.acid 1 14.361 513.44 286.36
## - X3.Hydroxyanthranilic.acid 1 14.427 513.51 286.40
## - Phenyl.sulfate 1 15.951 515.03 287.27
## - Pantothenol 1 17.940 517.02 288.40
## - Acetylglycine 1 18.160 517.24 288.52
## - AST..U.L. 1 18.254 517.34 288.58
## - X5.Aminopentanoic.acid 1 21.258 520.34 290.27
## - X3..3.Hydroxyphenyl..3.hydroxypropanoic.acid 1 24.195 523.28 291.92
## - Indole.3.methyl.acetate 1 25.380 524.46 292.58
## - X3.Hydroxypropionic.acid 1 25.524 524.61 292.66
## - Sphinganine 1 29.049 528.13 294.63
## - HDL.C..mM. 1 30.044 529.13 295.18
## - X1.5.Anhydrosorbitol 1 30.182 529.26 295.26
## - ALT..U.L. 1 34.680 533.76 297.73
## - Indole.3.acrylic.acid 1 45.935 545.02 303.85
## - Palmitoylethanolamide 1 55.701 554.78 309.05
## - X3.Indolebutyric.acid 1 59.761 558.84 311.19
## - TG..mM. 1 84.146 583.23 323.70
##
## Step: AIC=278.62
## FBG..mM. ~ ALT..U.L. + AST..U.L. + ALB..g.L. + TG..mM. + HDL.C..mM. +
## ALP..U.L. + T.BIL..uM. + D.BIL..uM. + TBA..uM. + NEUT.... +
## LYMPH.... + EO.... + Phenylethylamine + Octadecanamide +
## Urocanic.acid + Imidazolepropionic.acid + Indole.3.carboxaldehyde +
## X3.Hydroxyanthranilic.acid + Oleamide + Palmitoylethanolamide +
## Bilirubin...47 + Indole.3.acrylic.acid + Kynurenic.acid +
## Indole.3.methyl.acetate + Sphinganine + Sphinganine.1.phosphate +
## X3.Indolebutyric.acid + Phenylacetylglutamine.PAGln. + Pantothenol +
## Gamma.aminobutyric.acid + X5.Aminopentanoic.acid + N.Acetylcadaverine +
## Acetylcholine + N.acetyl.aspartic.acid + N8.Acetylspermidine +
## Spermine + Phenol + X1.5.Anhydrosorbitol + X3.Hydroxybenzoic.acid +
## Salicylic.acid + Phenyllactate + Bilirubin...82 + X3..3.Hydroxyphenyl..3.hydroxypropanoic.acid +
## X4.Hydroxyphenyllactate + p.Cresol.sulfate + X2.Hydroxy.Hippuric.Acid +
## X3.Hydroxyhippuric.acid + S.ganine.1.phosphate_b + Cholesterol.sulfate +
## Xanthurenic.acid + Cinnamoylglycine + Indoxyl.sulfate + Ascorbic.acid +
## Homovanillic.acid.sulfate + Iodide + Phenyl.sulfate + X4.Hydroxybenzoic.acid.4.O.sulphate +
## X3.Hydroxypropionic.acid + Acetylglycine + Hippuric.acid
##
## Df Sum of Sq RSS AIC
## - Hippuric.acid 1 1.051 501.10 277.23
## - X3.Hydroxybenzoic.acid 1 1.057 501.11 277.24
## - Iodide 1 1.150 501.20 277.29
## - X4.Hydroxybenzoic.acid.4.O.sulphate 1 1.422 501.47 277.45
## - X4.Hydroxyphenyllactate 1 2.011 502.06 277.79
## - Phenol 1 2.078 502.13 277.83
## - Spermine 1 2.182 502.23 277.89
## - Acetylcholine 1 2.192 502.24 277.90
## - ALP..U.L. 1 2.361 502.41 278.00
## - TBA..uM. 1 2.447 502.50 278.05
## - Urocanic.acid 1 2.688 502.74 278.19
## - Sphinganine.1.phosphate 1 2.738 502.79 278.22
## - N.acetyl.aspartic.acid 1 3.236 503.28 278.51
## - EO.... 1 3.417 503.47 278.61
## <none> 500.05 278.62
## - N8.Acetylspermidine 1 3.514 503.56 278.67
## - ALB..g.L. 1 3.717 503.76 278.79
## - Homovanillic.acid.sulfate 1 4.029 504.08 278.97
## - Bilirubin...47 1 4.325 504.37 279.14
## - X2.Hydroxy.Hippuric.Acid 1 5.079 505.13 279.58
## - Bilirubin...82 1 5.223 505.27 279.66
## - Phenyllactate 1 5.540 505.59 279.85
## - Cinnamoylglycine 1 5.772 505.82 279.98
## + Cre..uM. 1 0.966 499.08 280.05
## - N.Acetylcadaverine 1 6.029 506.08 280.13
## + Spermidine 1 0.567 499.48 280.29
## - Phenylacetylglutamine.PAGln. 1 6.319 506.37 280.30
## + Indole.3.propionic.acid 1 0.408 499.64 280.38
## + p.Cresol 1 0.390 499.66 280.39
## + CHE..U.L. 1 0.362 499.69 280.41
## + Sphingosine.1.phosphate 1 0.356 499.69 280.41
## + X4.Hydroxybenzoic.acid 1 0.340 499.71 280.42
## + Oleoylethanolamide 1 0.333 499.72 280.42
## + Dopa 1 0.288 499.76 280.45
## + Palmitic.amide 1 0.264 499.78 280.46
## + X3.Hydroxyphenylacetic.acid 1 0.258 499.79 280.47
## + TC..mM. 1 0.225 499.82 280.49
## - Cholesterol.sulfate 1 6.657 506.70 280.49
## + X4.Hydroxyphenylpropionate 1 0.200 499.85 280.50
## + Benzoic.acid 1 0.200 499.85 280.50
## + Putrescine 1 0.178 499.87 280.51
## + X5.Methoxyindoleacetate 1 0.174 499.87 280.52
## - Imidazolepropionic.acid 1 6.719 506.77 280.53
## + Biliverdin 1 0.151 499.90 280.53
## + Dopamine 1 0.142 499.91 280.53
## + Stearoylethanolamide 1 0.116 499.93 280.55
## + S.gosine.1.phosphate_b 1 0.106 499.94 280.56
## + Urea..mM. 1 0.071 499.98 280.58
## + BASO.... 1 0.068 499.98 280.58
## + Phenylacetic.acid 1 0.054 499.99 280.59
## + Sphingosine 1 0.049 500.00 280.59
## + X4.Ethylphenyl.sulfate 1 0.046 500.00 280.59
## + WBC..10.9.L. 1 0.033 500.01 280.60
## + Υ.GT..U.L. 1 0.013 500.03 280.61
## + LDL.C..mM. 1 0.009 500.04 280.61
## + UA..uM. 1 0.008 500.04 280.61
## + p.Cresol.glucuronide 1 0.005 500.04 280.61
## + Enterolactone 1 0.001 500.05 280.62
## - Phenylethylamine 1 6.972 507.02 280.67
## - T.BIL..uM. 1 7.059 507.11 280.72
## - D.BIL..uM. 1 7.466 507.51 280.96
## - Salicylic.acid 1 7.734 507.78 281.11
## - Octadecanamide 1 7.924 507.97 281.22
## - Indoxyl.sulfate 1 8.007 508.06 281.27
## - X3.Hydroxyhippuric.acid 1 8.709 508.76 281.68
## - Oleamide 1 8.715 508.76 281.68
## - Xanthurenic.acid 1 9.370 509.42 282.06
## - LYMPH.... 1 9.566 509.61 282.17
## - Gamma.aminobutyric.acid 1 9.799 509.85 282.30
## - p.Cresol.sulfate 1 9.889 509.94 282.36
## - S.ganine.1.phosphate_b 1 9.998 510.05 282.42
## - NEUT.... 1 10.679 510.73 282.81
## - Kynurenic.acid 1 13.316 513.36 284.32
## - Indole.3.carboxaldehyde 1 13.653 513.70 284.51
## - Ascorbic.acid 1 14.444 514.49 284.96
## - X3.Hydroxyanthranilic.acid 1 14.939 514.99 285.24
## - Phenyl.sulfate 1 15.653 515.70 285.65
## - AST..U.L. 1 17.766 517.81 286.85
## - Pantothenol 1 18.212 518.26 287.10
## - Acetylglycine 1 19.232 519.28 287.67
## - X5.Aminopentanoic.acid 1 20.954 521.00 288.65
## - X3..3.Hydroxyphenyl..3.hydroxypropanoic.acid 1 24.295 524.34 290.52
## - X3.Hydroxypropionic.acid 1 25.811 525.86 291.36
## - Indole.3.methyl.acetate 1 26.522 526.57 291.76
## - Sphinganine 1 28.926 528.97 293.09
## - X1.5.Anhydrosorbitol 1 30.057 530.11 293.72
## - HDL.C..mM. 1 30.316 530.36 293.86
## - ALT..U.L. 1 34.963 535.01 296.42
## - Indole.3.acrylic.acid 1 46.886 546.93 302.88
## - Palmitoylethanolamide 1 55.702 555.75 307.56
## - X3.Indolebutyric.acid 1 59.950 560.00 309.79
## - TG..mM. 1 83.835 583.88 322.03
##
## Step: AIC=277.23
## FBG..mM. ~ ALT..U.L. + AST..U.L. + ALB..g.L. + TG..mM. + HDL.C..mM. +
## ALP..U.L. + T.BIL..uM. + D.BIL..uM. + TBA..uM. + NEUT.... +
## LYMPH.... + EO.... + Phenylethylamine + Octadecanamide +
## Urocanic.acid + Imidazolepropionic.acid + Indole.3.carboxaldehyde +
## X3.Hydroxyanthranilic.acid + Oleamide + Palmitoylethanolamide +
## Bilirubin...47 + Indole.3.acrylic.acid + Kynurenic.acid +
## Indole.3.methyl.acetate + Sphinganine + Sphinganine.1.phosphate +
## X3.Indolebutyric.acid + Phenylacetylglutamine.PAGln. + Pantothenol +
## Gamma.aminobutyric.acid + X5.Aminopentanoic.acid + N.Acetylcadaverine +
## Acetylcholine + N.acetyl.aspartic.acid + N8.Acetylspermidine +
## Spermine + Phenol + X1.5.Anhydrosorbitol + X3.Hydroxybenzoic.acid +
## Salicylic.acid + Phenyllactate + Bilirubin...82 + X3..3.Hydroxyphenyl..3.hydroxypropanoic.acid +
## X4.Hydroxyphenyllactate + p.Cresol.sulfate + X2.Hydroxy.Hippuric.Acid +
## X3.Hydroxyhippuric.acid + S.ganine.1.phosphate_b + Cholesterol.sulfate +
## Xanthurenic.acid + Cinnamoylglycine + Indoxyl.sulfate + Ascorbic.acid +
## Homovanillic.acid.sulfate + Iodide + Phenyl.sulfate + X4.Hydroxybenzoic.acid.4.O.sulphate +
## X3.Hydroxypropionic.acid + Acetylglycine
##
## Df Sum of Sq RSS AIC
## - X3.Hydroxybenzoic.acid 1 1.017 502.12 275.83
## - Iodide 1 1.143 502.24 275.90
## - X4.Hydroxybenzoic.acid.4.O.sulphate 1 1.811 502.91 276.29
## - X4.Hydroxyphenyllactate 1 1.928 503.03 276.36
## - Spermine 1 2.113 503.21 276.47
## - Acetylcholine 1 2.248 503.35 276.54
## - Phenol 1 2.298 503.40 276.57
## - ALP..U.L. 1 2.330 503.43 276.59
## - TBA..uM. 1 2.414 503.51 276.64
## - Urocanic.acid 1 2.650 503.75 276.78
## - EO.... 1 3.206 504.30 277.10
## - N.acetyl.aspartic.acid 1 3.269 504.37 277.14
## - Sphinganine.1.phosphate 1 3.403 504.50 277.22
## <none> 501.10 277.23
## - N8.Acetylspermidine 1 3.555 504.65 277.30
## - ALB..g.L. 1 3.763 504.86 277.42
## - Homovanillic.acid.sulfate 1 3.846 504.94 277.47
## - Bilirubin...47 1 4.785 505.88 278.02
## - Cinnamoylglycine 1 4.840 505.94 278.05
## - X2.Hydroxy.Hippuric.Acid 1 5.146 506.24 278.23
## - Bilirubin...82 1 5.672 506.77 278.53
## + Hippuric.acid 1 1.051 500.05 278.62
## - Phenyllactate 1 5.934 507.03 278.68
## + Cre..uM. 1 0.855 500.24 278.73
## - N.Acetylcadaverine 1 6.169 507.27 278.82
## - Phenylacetylglutamine.PAGln. 1 6.378 507.48 278.94
## + Spermidine 1 0.466 500.63 278.96
## + X4.Hydroxybenzoic.acid 1 0.386 500.71 279.01
## + CHE..U.L. 1 0.377 500.72 279.01
## + Indole.3.propionic.acid 1 0.373 500.73 279.01
## + X4.Hydroxyphenylpropionate 1 0.354 500.74 279.03
## + Sphingosine.1.phosphate 1 0.340 500.76 279.03
## + Oleoylethanolamide 1 0.330 500.77 279.04
## + X5.Methoxyindoleacetate 1 0.280 500.82 279.07
## + X3.Hydroxyphenylacetic.acid 1 0.270 500.83 279.07
## + TC..mM. 1 0.248 500.85 279.09
## + Palmitic.amide 1 0.231 500.87 279.10
## + p.Cresol 1 0.221 500.88 279.10
## + Benzoic.acid 1 0.196 500.90 279.12
## + Dopamine 1 0.165 500.93 279.14
## + S.gosine.1.phosphate_b 1 0.125 500.97 279.16
## + Dopa 1 0.118 500.98 279.16
## - Cholesterol.sulfate 1 6.772 507.87 279.17
## + Biliverdin 1 0.108 500.99 279.17
## + Putrescine 1 0.099 501.00 279.17
## + Stearoylethanolamide 1 0.093 501.01 279.18
## + X4.Ethylphenyl.sulfate 1 0.080 501.02 279.19
## + BASO.... 1 0.067 501.03 279.19
## + Sphingosine 1 0.058 501.04 279.20
## + Urea..mM. 1 0.042 501.06 279.21
## + Phenylacetic.acid 1 0.042 501.06 279.21
## + UA..uM. 1 0.023 501.08 279.22
## + WBC..10.9.L. 1 0.023 501.08 279.22
## + p.Cresol.glucuronide 1 0.023 501.08 279.22
## + LDL.C..mM. 1 0.009 501.09 279.23
## + Υ.GT..U.L. 1 0.006 501.09 279.23
## + Enterolactone 1 0.003 501.10 279.23
## - Imidazolepropionic.acid 1 6.900 508.00 279.24
## - Phenylethylamine 1 7.487 508.59 279.58
## - T.BIL..uM. 1 7.520 508.62 279.60
## - Salicylic.acid 1 7.838 508.94 279.78
## - D.BIL..uM. 1 7.969 509.07 279.86
## - Octadecanamide 1 8.040 509.14 279.90
## - Indoxyl.sulfate 1 8.225 509.32 280.00
## - Oleamide 1 8.477 509.58 280.15
## - X3.Hydroxyhippuric.acid 1 9.037 510.14 280.47
## - LYMPH.... 1 9.118 510.22 280.52
## - Gamma.aminobutyric.acid 1 9.716 510.81 280.86
## - Xanthurenic.acid 1 9.810 510.91 280.91
## - NEUT.... 1 10.150 511.25 281.11
## - p.Cresol.sulfate 1 10.810 511.91 281.49
## - S.ganine.1.phosphate_b 1 11.408 512.51 281.83
## - Indole.3.carboxaldehyde 1 13.041 514.14 282.76
## - Kynurenic.acid 1 14.226 515.33 283.44
## - Ascorbic.acid 1 14.691 515.79 283.70
## - Phenyl.sulfate 1 15.309 516.41 284.05
## - X3.Hydroxyanthranilic.acid 1 15.724 516.82 284.29
## - AST..U.L. 1 18.086 519.19 285.62
## - Acetylglycine 1 18.618 519.72 285.92
## - Pantothenol 1 19.542 520.64 286.44
## - X5.Aminopentanoic.acid 1 21.227 522.33 287.39
## - X3..3.Hydroxyphenyl..3.hydroxypropanoic.acid 1 23.467 524.57 288.64
## - X3.Hydroxypropionic.acid 1 25.935 527.03 290.02
## - Indole.3.methyl.acetate 1 26.277 527.38 290.21
## - Sphinganine 1 29.071 530.17 291.76
## - X1.5.Anhydrosorbitol 1 29.908 531.01 292.22
## - HDL.C..mM. 1 30.719 531.82 292.67
## - ALT..U.L. 1 35.258 536.36 295.16
## - Indole.3.acrylic.acid 1 46.344 547.44 301.15
## - Palmitoylethanolamide 1 54.651 555.75 305.56
## - X3.Indolebutyric.acid 1 60.818 561.92 308.80
## - TG..mM. 1 83.136 584.23 320.21
##
## Step: AIC=275.83
## FBG..mM. ~ ALT..U.L. + AST..U.L. + ALB..g.L. + TG..mM. + HDL.C..mM. +
## ALP..U.L. + T.BIL..uM. + D.BIL..uM. + TBA..uM. + NEUT.... +
## LYMPH.... + EO.... + Phenylethylamine + Octadecanamide +
## Urocanic.acid + Imidazolepropionic.acid + Indole.3.carboxaldehyde +
## X3.Hydroxyanthranilic.acid + Oleamide + Palmitoylethanolamide +
## Bilirubin...47 + Indole.3.acrylic.acid + Kynurenic.acid +
## Indole.3.methyl.acetate + Sphinganine + Sphinganine.1.phosphate +
## X3.Indolebutyric.acid + Phenylacetylglutamine.PAGln. + Pantothenol +
## Gamma.aminobutyric.acid + X5.Aminopentanoic.acid + N.Acetylcadaverine +
## Acetylcholine + N.acetyl.aspartic.acid + N8.Acetylspermidine +
## Spermine + Phenol + X1.5.Anhydrosorbitol + Salicylic.acid +
## Phenyllactate + Bilirubin...82 + X3..3.Hydroxyphenyl..3.hydroxypropanoic.acid +
## X4.Hydroxyphenyllactate + p.Cresol.sulfate + X2.Hydroxy.Hippuric.Acid +
## X3.Hydroxyhippuric.acid + S.ganine.1.phosphate_b + Cholesterol.sulfate +
## Xanthurenic.acid + Cinnamoylglycine + Indoxyl.sulfate + Ascorbic.acid +
## Homovanillic.acid.sulfate + Iodide + Phenyl.sulfate + X4.Hydroxybenzoic.acid.4.O.sulphate +
## X3.Hydroxypropionic.acid + Acetylglycine
##
## Df Sum of Sq RSS AIC
## - Iodide 1 1.011 503.13 274.42
## - X4.Hydroxybenzoic.acid.4.O.sulphate 1 1.644 503.76 274.78
## - X4.Hydroxyphenyllactate 1 1.940 504.06 274.96
## - Spermine 1 2.076 504.19 275.04
## - TBA..uM. 1 2.121 504.24 275.06
## - ALP..U.L. 1 2.146 504.26 275.08
## - Phenol 1 2.396 504.51 275.22
## - Acetylcholine 1 2.625 504.74 275.35
## - Urocanic.acid 1 2.717 504.83 275.41
## - EO.... 1 3.351 505.47 275.78
## <none> 502.12 275.83
## - N.acetyl.aspartic.acid 1 3.547 505.66 275.89
## - Sphinganine.1.phosphate 1 3.603 505.72 275.92
## - N8.Acetylspermidine 1 3.719 505.83 275.99
## - Homovanillic.acid.sulfate 1 3.764 505.88 276.02
## - ALB..g.L. 1 4.012 506.13 276.16
## - Bilirubin...47 1 4.651 506.77 276.53
## - X2.Hydroxy.Hippuric.Acid 1 5.328 507.44 276.92
## - Cinnamoylglycine 1 5.612 507.73 277.08
## - Bilirubin...82 1 5.794 507.91 277.19
## + X3.Hydroxybenzoic.acid 1 1.017 501.10 277.23
## + Hippuric.acid 1 1.011 501.11 277.24
## - Phenyllactate 1 6.049 508.16 277.34
## + Cre..uM. 1 0.807 501.31 277.36
## + X3.Hydroxyphenylacetic.acid 1 0.586 501.53 277.48
## + Spermidine 1 0.536 501.58 277.51
## - Phenylacetylglutamine.PAGln. 1 6.404 508.52 277.54
## - Cholesterol.sulfate 1 6.420 508.54 277.55
## + Oleoylethanolamide 1 0.474 501.64 277.55
## + X4.Hydroxybenzoic.acid 1 0.375 501.74 277.61
## + Indole.3.propionic.acid 1 0.347 501.77 277.62
## + Sphingosine.1.phosphate 1 0.323 501.79 277.64
## + X5.Methoxyindoleacetate 1 0.314 501.80 277.64
## + Benzoic.acid 1 0.302 501.81 277.65
## + X4.Hydroxyphenylpropionate 1 0.276 501.84 277.67
## + p.Cresol 1 0.240 501.88 277.69
## + Palmitic.amide 1 0.229 501.89 277.69
## + Biliverdin 1 0.191 501.92 277.72
## + Dopa 1 0.182 501.93 277.72
## + TC..mM. 1 0.178 501.94 277.72
## + CHE..U.L. 1 0.167 501.95 277.73
## + Stearoylethanolamide 1 0.140 501.98 277.75
## + Sphingosine 1 0.124 501.99 277.75
## + BASO.... 1 0.119 502.00 277.76
## + Putrescine 1 0.119 502.00 277.76
## + S.gosine.1.phosphate_b 1 0.118 502.00 277.76
## - Imidazolepropionic.acid 1 6.801 508.92 277.77
## + X4.Ethylphenyl.sulfate 1 0.089 502.03 277.77
## + Urea..mM. 1 0.067 502.05 277.79
## + Dopamine 1 0.063 502.05 277.79
## + Υ.GT..U.L. 1 0.030 502.09 277.81
## + UA..uM. 1 0.027 502.09 277.81
## + Phenylacetic.acid 1 0.016 502.10 277.82
## + LDL.C..mM. 1 0.014 502.10 277.82
## + WBC..10.9.L. 1 0.010 502.11 277.82
## + Enterolactone 1 0.001 502.12 277.83
## + p.Cresol.glucuronide 1 0.000 502.12 277.83
## - N.Acetylcadaverine 1 7.057 509.17 277.92
## - T.BIL..uM. 1 7.267 509.38 278.04
## - Phenylethylamine 1 7.636 509.75 278.25
## - D.BIL..uM. 1 7.643 509.76 278.25
## - Octadecanamide 1 7.728 509.84 278.30
## - Salicylic.acid 1 8.028 510.14 278.47
## - Indoxyl.sulfate 1 8.129 510.24 278.53
## - Oleamide 1 8.334 510.45 278.65
## - Gamma.aminobutyric.acid 1 8.919 511.03 278.99
## - LYMPH.... 1 9.333 511.45 279.22
## - X3.Hydroxyhippuric.acid 1 9.391 511.51 279.26
## - NEUT.... 1 10.037 512.15 279.63
## - Xanthurenic.acid 1 10.057 512.17 279.64
## - p.Cresol.sulfate 1 11.523 513.64 280.48
## - S.ganine.1.phosphate_b 1 12.134 514.25 280.82
## - Indole.3.carboxaldehyde 1 13.209 515.32 281.43
## - Kynurenic.acid 1 14.384 516.50 282.10
## - Ascorbic.acid 1 14.441 516.56 282.13
## - Phenyl.sulfate 1 15.253 517.37 282.60
## - X3.Hydroxyanthranilic.acid 1 16.395 518.51 283.24
## - AST..U.L. 1 17.908 520.02 284.09
## - Pantothenol 1 19.854 521.97 285.19
## - X5.Aminopentanoic.acid 1 20.952 523.07 285.80
## - Acetylglycine 1 21.246 523.36 285.97
## - X3..3.Hydroxyphenyl..3.hydroxypropanoic.acid 1 23.769 525.88 287.38
## - Indole.3.methyl.acetate 1 25.691 527.81 288.45
## - X3.Hydroxypropionic.acid 1 26.796 528.91 289.06
## - Sphinganine 1 28.740 530.86 290.14
## - X1.5.Anhydrosorbitol 1 29.332 531.45 290.46
## - HDL.C..mM. 1 30.481 532.60 291.09
## - ALT..U.L. 1 35.135 537.25 293.64
## - Indole.3.acrylic.acid 1 45.676 547.79 299.34
## - Palmitoylethanolamide 1 55.075 557.19 304.32
## - X3.Indolebutyric.acid 1 60.408 562.52 307.11
## - TG..mM. 1 82.134 584.25 318.22
##
## Step: AIC=274.42
## FBG..mM. ~ ALT..U.L. + AST..U.L. + ALB..g.L. + TG..mM. + HDL.C..mM. +
## ALP..U.L. + T.BIL..uM. + D.BIL..uM. + TBA..uM. + NEUT.... +
## LYMPH.... + EO.... + Phenylethylamine + Octadecanamide +
## Urocanic.acid + Imidazolepropionic.acid + Indole.3.carboxaldehyde +
## X3.Hydroxyanthranilic.acid + Oleamide + Palmitoylethanolamide +
## Bilirubin...47 + Indole.3.acrylic.acid + Kynurenic.acid +
## Indole.3.methyl.acetate + Sphinganine + Sphinganine.1.phosphate +
## X3.Indolebutyric.acid + Phenylacetylglutamine.PAGln. + Pantothenol +
## Gamma.aminobutyric.acid + X5.Aminopentanoic.acid + N.Acetylcadaverine +
## Acetylcholine + N.acetyl.aspartic.acid + N8.Acetylspermidine +
## Spermine + Phenol + X1.5.Anhydrosorbitol + Salicylic.acid +
## Phenyllactate + Bilirubin...82 + X3..3.Hydroxyphenyl..3.hydroxypropanoic.acid +
## X4.Hydroxyphenyllactate + p.Cresol.sulfate + X2.Hydroxy.Hippuric.Acid +
## X3.Hydroxyhippuric.acid + S.ganine.1.phosphate_b + Cholesterol.sulfate +
## Xanthurenic.acid + Cinnamoylglycine + Indoxyl.sulfate + Ascorbic.acid +
## Homovanillic.acid.sulfate + Phenyl.sulfate + X4.Hydroxybenzoic.acid.4.O.sulphate +
## X3.Hydroxypropionic.acid + Acetylglycine
##
## Df Sum of Sq RSS AIC
## - X4.Hydroxybenzoic.acid.4.O.sulphate 1 1.631 504.76 273.36
## - X4.Hydroxyphenyllactate 1 1.841 504.97 273.49
## - Spermine 1 1.861 504.99 273.50
## - ALP..U.L. 1 2.205 505.33 273.70
## - Phenol 1 2.377 505.50 273.80
## - Acetylcholine 1 2.465 505.59 273.85
## - TBA..uM. 1 2.476 505.60 273.85
## - Urocanic.acid 1 2.930 506.06 274.12
## - Sphinganine.1.phosphate 1 3.291 506.42 274.33
## <none> 503.13 274.42
## - EO.... 1 3.488 506.62 274.44
## - N.acetyl.aspartic.acid 1 3.693 506.82 274.56
## - N8.Acetylspermidine 1 4.050 507.18 274.77
## - Homovanillic.acid.sulfate 1 4.143 507.27 274.82
## - Bilirubin...47 1 4.401 507.53 274.97
## - ALB..g.L. 1 4.480 507.61 275.01
## - X2.Hydroxy.Hippuric.Acid 1 5.489 508.62 275.60
## - Bilirubin...82 1 5.773 508.90 275.76
## - Cinnamoylglycine 1 5.855 508.98 275.81
## + Iodide 1 1.011 502.12 275.83
## + Hippuric.acid 1 1.006 502.12 275.83
## + Cre..uM. 1 0.963 502.16 275.86
## + X3.Hydroxybenzoic.acid 1 0.886 502.24 275.90
## - Phenyllactate 1 6.032 509.16 275.91
## + X3.Hydroxyphenylacetic.acid 1 0.557 502.57 276.09
## + Spermidine 1 0.488 502.64 276.13
## - Imidazolepropionic.acid 1 6.425 509.55 276.13
## - Phenylacetylglutamine.PAGln. 1 6.428 509.55 276.14
## + X4.Hydroxybenzoic.acid 1 0.465 502.66 276.15
## + Indole.3.propionic.acid 1 0.395 502.73 276.19
## + Sphingosine.1.phosphate 1 0.363 502.76 276.20
## + X4.Hydroxyphenylpropionate 1 0.309 502.82 276.24
## + Oleoylethanolamide 1 0.309 502.82 276.24
## - N.Acetylcadaverine 1 6.612 509.74 276.24
## + Benzoic.acid 1 0.267 502.86 276.26
## + p.Cresol 1 0.256 502.87 276.27
## + X5.Methoxyindoleacetate 1 0.223 502.90 276.29
## + Biliverdin 1 0.188 502.94 276.31
## + CHE..U.L. 1 0.186 502.94 276.31
## + Stearoylethanolamide 1 0.176 502.95 276.31
## + Urea..mM. 1 0.174 502.95 276.32
## + Dopa 1 0.174 502.95 276.32
## + Palmitic.amide 1 0.171 502.96 276.32
## + Putrescine 1 0.165 502.96 276.32
## + S.gosine.1.phosphate_b 1 0.155 502.97 276.33
## + TC..mM. 1 0.135 502.99 276.34
## + BASO.... 1 0.126 503.00 276.34
## + Dopamine 1 0.100 503.03 276.36
## + Sphingosine 1 0.086 503.04 276.37
## + Υ.GT..U.L. 1 0.035 503.09 276.40
## + X4.Ethylphenyl.sulfate 1 0.032 503.10 276.40
## + LDL.C..mM. 1 0.021 503.11 276.40
## + Phenylacetic.acid 1 0.020 503.11 276.40
## + WBC..10.9.L. 1 0.013 503.11 276.41
## + UA..uM. 1 0.008 503.12 276.41
## + p.Cresol.glucuronide 1 0.003 503.12 276.41
## + Enterolactone 1 0.001 503.13 276.42
## - Cholesterol.sulfate 1 7.048 510.18 276.49
## - T.BIL..uM. 1 7.650 510.78 276.84
## - Phenylethylamine 1 7.914 511.04 276.99
## - D.BIL..uM. 1 8.048 511.18 277.07
## - Salicylic.acid 1 8.437 511.56 277.29
## - Octadecanamide 1 8.518 511.64 277.34
## - Indoxyl.sulfate 1 9.022 512.15 277.62
## - LYMPH.... 1 9.090 512.22 277.66
## - Oleamide 1 9.091 512.22 277.66
## - Gamma.aminobutyric.acid 1 9.216 512.34 277.74
## - X3.Hydroxyhippuric.acid 1 9.367 512.49 277.82
## - Xanthurenic.acid 1 9.551 512.68 277.93
## - NEUT.... 1 9.893 513.02 278.12
## - p.Cresol.sulfate 1 11.265 514.39 278.90
## - S.ganine.1.phosphate_b 1 11.713 514.84 279.16
## - Ascorbic.acid 1 13.859 516.99 280.38
## - Indole.3.carboxaldehyde 1 14.625 517.75 280.81
## - Phenyl.sulfate 1 14.929 518.06 280.98
## - Kynurenic.acid 1 15.157 518.28 281.11
## - X3.Hydroxyanthranilic.acid 1 16.125 519.25 281.66
## - AST..U.L. 1 19.055 522.18 283.31
## - Pantothenol 1 19.543 522.67 283.58
## - X5.Aminopentanoic.acid 1 21.179 524.31 284.50
## - Acetylglycine 1 22.151 525.28 285.04
## - X3..3.Hydroxyphenyl..3.hydroxypropanoic.acid 1 23.214 526.34 285.63
## - X3.Hydroxypropionic.acid 1 25.835 528.96 287.09
## - Indole.3.methyl.acetate 1 26.979 530.11 287.72
## - Sphinganine 1 28.336 531.46 288.47
## - X1.5.Anhydrosorbitol 1 29.269 532.40 288.98
## - HDL.C..mM. 1 33.550 536.68 291.33
## - ALT..U.L. 1 37.612 540.74 293.54
## - Indole.3.acrylic.acid 1 47.984 551.11 299.11
## - Palmitoylethanolamide 1 54.554 557.68 302.58
## - X3.Indolebutyric.acid 1 60.392 563.52 305.63
## - TG..mM. 1 85.954 589.08 318.63
##
## Step: AIC=273.36
## FBG..mM. ~ ALT..U.L. + AST..U.L. + ALB..g.L. + TG..mM. + HDL.C..mM. +
## ALP..U.L. + T.BIL..uM. + D.BIL..uM. + TBA..uM. + NEUT.... +
## LYMPH.... + EO.... + Phenylethylamine + Octadecanamide +
## Urocanic.acid + Imidazolepropionic.acid + Indole.3.carboxaldehyde +
## X3.Hydroxyanthranilic.acid + Oleamide + Palmitoylethanolamide +
## Bilirubin...47 + Indole.3.acrylic.acid + Kynurenic.acid +
## Indole.3.methyl.acetate + Sphinganine + Sphinganine.1.phosphate +
## X3.Indolebutyric.acid + Phenylacetylglutamine.PAGln. + Pantothenol +
## Gamma.aminobutyric.acid + X5.Aminopentanoic.acid + N.Acetylcadaverine +
## Acetylcholine + N.acetyl.aspartic.acid + N8.Acetylspermidine +
## Spermine + Phenol + X1.5.Anhydrosorbitol + Salicylic.acid +
## Phenyllactate + Bilirubin...82 + X3..3.Hydroxyphenyl..3.hydroxypropanoic.acid +
## X4.Hydroxyphenyllactate + p.Cresol.sulfate + X2.Hydroxy.Hippuric.Acid +
## X3.Hydroxyhippuric.acid + S.ganine.1.phosphate_b + Cholesterol.sulfate +
## Xanthurenic.acid + Cinnamoylglycine + Indoxyl.sulfate + Ascorbic.acid +
## Homovanillic.acid.sulfate + Phenyl.sulfate + X3.Hydroxypropionic.acid +
## Acetylglycine
##
## Df Sum of Sq RSS AIC
## - X4.Hydroxyphenyllactate 1 1.190 505.95 272.05
## - Spermine 1 1.533 506.29 272.25
## - ALP..U.L. 1 1.913 506.67 272.47
## - Acetylcholine 1 2.084 506.84 272.57
## - TBA..uM. 1 2.210 506.97 272.64
## - Phenol 1 2.791 507.55 272.98
## - Urocanic.acid 1 2.899 507.66 273.04
## - N.acetyl.aspartic.acid 1 3.336 508.09 273.29
## - EO.... 1 3.358 508.12 273.31
## <none> 504.76 273.36
## - Sphinganine.1.phosphate 1 3.555 508.31 273.42
## - Homovanillic.acid.sulfate 1 3.719 508.48 273.52
## - Bilirubin...47 1 4.205 508.96 273.80
## - N8.Acetylspermidine 1 4.449 509.21 273.94
## - Phenyllactate 1 4.631 509.39 274.04
## - ALB..g.L. 1 5.188 509.95 274.36
## + X4.Hydroxybenzoic.acid.4.O.sulphate 1 1.631 503.13 274.42
## - X2.Hydroxy.Hippuric.Acid 1 5.532 510.29 274.56
## + Hippuric.acid 1 1.370 503.39 274.57
## + Iodide 1 0.998 503.76 274.78
## - Cinnamoylglycine 1 6.047 510.80 274.85
## + Cre..uM. 1 0.802 503.96 274.90
## - Cholesterol.sulfate 1 6.182 510.94 274.93
## + X3.Hydroxybenzoic.acid 1 0.733 504.03 274.94
## + X3.Hydroxyphenylacetic.acid 1 0.615 504.14 275.01
## - Imidazolepropionic.acid 1 6.316 511.07 275.01
## + Oleoylethanolamide 1 0.446 504.31 275.11
## + X4.Hydroxybenzoic.acid 1 0.440 504.32 275.11
## + X5.Methoxyindoleacetate 1 0.433 504.32 275.11
## + X4.Hydroxyphenylpropionate 1 0.406 504.35 275.13
## + Biliverdin 1 0.402 504.36 275.13
## - Bilirubin...82 1 6.587 511.35 275.16
## + Spermidine 1 0.320 504.44 275.18
## + Stearoylethanolamide 1 0.310 504.45 275.18
## + Indole.3.propionic.acid 1 0.253 504.50 275.22
## + Benzoic.acid 1 0.223 504.53 275.23
## + Sphingosine.1.phosphate 1 0.191 504.57 275.25
## + CHE..U.L. 1 0.159 504.60 275.27
## + Dopamine 1 0.156 504.60 275.27
## + BASO.... 1 0.154 504.60 275.28
## + Sphingosine 1 0.143 504.61 275.28
## + Urea..mM. 1 0.143 504.61 275.28
## + TC..mM. 1 0.133 504.63 275.29
## + Palmitic.amide 1 0.113 504.64 275.30
## + X4.Ethylphenyl.sulfate 1 0.105 504.65 275.30
## + p.Cresol.glucuronide 1 0.090 504.67 275.31
## + Phenylacetic.acid 1 0.077 504.68 275.32
## + Dopa 1 0.061 504.70 275.33
## + S.gosine.1.phosphate_b 1 0.045 504.71 275.34
## + WBC..10.9.L. 1 0.044 504.71 275.34
## + UA..uM. 1 0.029 504.73 275.35
## + Enterolactone 1 0.018 504.74 275.35
## + p.Cresol 1 0.015 504.74 275.36
## + Putrescine 1 0.012 504.75 275.36
## + LDL.C..mM. 1 0.012 504.75 275.36
## + Υ.GT..U.L. 1 0.005 504.75 275.36
## - Phenylacetylglutamine.PAGln. 1 7.656 512.41 275.78
## - D.BIL..uM. 1 7.676 512.43 275.79
## - Octadecanamide 1 7.714 512.47 275.81
## - N.Acetylcadaverine 1 7.747 512.50 275.83
## - Oleamide 1 7.956 512.71 275.95
## - T.BIL..uM. 1 8.178 512.94 276.07
## - Salicylic.acid 1 8.582 513.34 276.30
## - Phenylethylamine 1 8.690 513.45 276.37
## - Xanthurenic.acid 1 8.997 513.75 276.54
## - X3.Hydroxyhippuric.acid 1 9.000 513.76 276.54
## - LYMPH.... 1 9.120 513.88 276.61
## - NEUT.... 1 9.843 514.60 277.02
## - Gamma.aminobutyric.acid 1 11.033 515.79 277.70
## - Indoxyl.sulfate 1 11.418 516.18 277.92
## - S.ganine.1.phosphate_b 1 12.348 517.11 278.45
## - p.Cresol.sulfate 1 12.914 517.67 278.77
## - Ascorbic.acid 1 14.995 519.75 279.94
## - Kynurenic.acid 1 15.279 520.04 280.10
## - Phenyl.sulfate 1 15.593 520.35 280.28
## - X3.Hydroxyanthranilic.acid 1 16.764 521.52 280.94
## - Indole.3.carboxaldehyde 1 16.821 521.58 280.97
## - Pantothenol 1 18.837 523.59 282.10
## - AST..U.L. 1 19.078 523.84 282.23
## - X5.Aminopentanoic.acid 1 20.700 525.46 283.14
## - Acetylglycine 1 22.496 527.25 284.14
## - X3..3.Hydroxyphenyl..3.hydroxypropanoic.acid 1 22.764 527.52 284.29
## - X3.Hydroxypropionic.acid 1 26.326 531.08 286.26
## - Indole.3.methyl.acetate 1 27.363 532.12 286.83
## - X1.5.Anhydrosorbitol 1 30.106 534.86 288.34
## - Sphinganine 1 32.106 536.86 289.43
## - HDL.C..mM. 1 33.827 538.58 290.37
## - ALT..U.L. 1 36.974 541.73 292.08
## - Indole.3.acrylic.acid 1 48.917 553.67 298.47
## - Palmitoylethanolamide 1 56.026 560.78 302.20
## - X3.Indolebutyric.acid 1 60.837 565.59 304.71
## - TG..mM. 1 85.139 589.90 317.03
##
## Step: AIC=272.05
## FBG..mM. ~ ALT..U.L. + AST..U.L. + ALB..g.L. + TG..mM. + HDL.C..mM. +
## ALP..U.L. + T.BIL..uM. + D.BIL..uM. + TBA..uM. + NEUT.... +
## LYMPH.... + EO.... + Phenylethylamine + Octadecanamide +
## Urocanic.acid + Imidazolepropionic.acid + Indole.3.carboxaldehyde +
## X3.Hydroxyanthranilic.acid + Oleamide + Palmitoylethanolamide +
## Bilirubin...47 + Indole.3.acrylic.acid + Kynurenic.acid +
## Indole.3.methyl.acetate + Sphinganine + Sphinganine.1.phosphate +
## X3.Indolebutyric.acid + Phenylacetylglutamine.PAGln. + Pantothenol +
## Gamma.aminobutyric.acid + X5.Aminopentanoic.acid + N.Acetylcadaverine +
## Acetylcholine + N.acetyl.aspartic.acid + N8.Acetylspermidine +
## Spermine + Phenol + X1.5.Anhydrosorbitol + Salicylic.acid +
## Phenyllactate + Bilirubin...82 + X3..3.Hydroxyphenyl..3.hydroxypropanoic.acid +
## p.Cresol.sulfate + X2.Hydroxy.Hippuric.Acid + X3.Hydroxyhippuric.acid +
## S.ganine.1.phosphate_b + Cholesterol.sulfate + Xanthurenic.acid +
## Cinnamoylglycine + Indoxyl.sulfate + Ascorbic.acid + Homovanillic.acid.sulfate +
## Phenyl.sulfate + X3.Hydroxypropionic.acid + Acetylglycine
##
## Df Sum of Sq RSS AIC
## - Spermine 1 1.603 507.55 270.98
## - ALP..U.L. 1 1.651 507.60 271.01
## - TBA..uM. 1 1.812 507.76 271.10
## - Acetylcholine 1 1.937 507.88 271.17
## - Phenol 1 2.832 508.78 271.69
## - N.acetyl.aspartic.acid 1 3.116 509.06 271.85
## - Urocanic.acid 1 3.127 509.07 271.86
## <none> 505.95 272.05
## - Phenyllactate 1 3.502 509.45 272.07
## - EO.... 1 3.649 509.60 272.16
## - Bilirubin...47 1 3.825 509.77 272.26
## - Sphinganine.1.phosphate 1 3.950 509.90 272.33
## - Homovanillic.acid.sulfate 1 3.991 509.94 272.36
## - N8.Acetylspermidine 1 4.525 510.47 272.66
## - X2.Hydroxy.Hippuric.Acid 1 5.378 511.33 273.15
## + Cre..uM. 1 1.335 504.61 273.28
## - ALB..g.L. 1 5.728 511.68 273.35
## + Hippuric.acid 1 1.209 504.74 273.35
## + X4.Hydroxyphenyllactate 1 1.190 504.76 273.36
## - Cholesterol.sulfate 1 5.829 511.78 273.41
## + X4.Hydroxybenzoic.acid.4.O.sulphate 1 0.979 504.97 273.49
## - Cinnamoylglycine 1 6.013 511.96 273.52
## + Iodide 1 0.919 505.03 273.52
## - Bilirubin...82 1 6.085 512.03 273.56
## - Imidazolepropionic.acid 1 6.132 512.08 273.58
## + X3.Hydroxybenzoic.acid 1 0.774 505.17 273.61
## + Biliverdin 1 0.537 505.41 273.74
## + X4.Hydroxybenzoic.acid 1 0.506 505.44 273.76
## + Spermidine 1 0.496 505.45 273.77
## + Stearoylethanolamide 1 0.495 505.45 273.77
## + X4.Hydroxyphenylpropionate 1 0.483 505.46 273.77
## + Oleoylethanolamide 1 0.398 505.55 273.82
## + X3.Hydroxyphenylacetic.acid 1 0.363 505.58 273.84
## + Indole.3.propionic.acid 1 0.296 505.65 273.88
## + X5.Methoxyindoleacetate 1 0.251 505.70 273.91
## + X4.Ethylphenyl.sulfate 1 0.205 505.74 273.94
## + Benzoic.acid 1 0.200 505.75 273.94
## + Sphingosine 1 0.179 505.77 273.95
## + p.Cresol.glucuronide 1 0.176 505.77 273.95
## + p.Cresol 1 0.158 505.79 273.96
## + CHE..U.L. 1 0.155 505.79 273.96
## + TC..mM. 1 0.139 505.81 273.97
## + Dopamine 1 0.121 505.83 273.98
## + Sphingosine.1.phosphate 1 0.118 505.83 273.99
## + Urea..mM. 1 0.117 505.83 273.99
## + Dopa 1 0.106 505.84 273.99
## + Palmitic.amide 1 0.083 505.86 274.01
## + BASO.... 1 0.064 505.88 274.02
## + Enterolactone 1 0.031 505.92 274.04
## + Putrescine 1 0.029 505.92 274.04
## + Phenylacetic.acid 1 0.018 505.93 274.04
## + S.gosine.1.phosphate_b 1 0.016 505.93 274.05
## + WBC..10.9.L. 1 0.015 505.93 274.05
## + Υ.GT..U.L. 1 0.010 505.94 274.05
## + LDL.C..mM. 1 0.002 505.95 274.05
## + UA..uM. 1 0.000 505.95 274.05
## - Phenylacetylglutamine.PAGln. 1 7.304 513.25 274.25
## - D.BIL..uM. 1 7.706 513.65 274.48
## - Octadecanamide 1 7.709 513.66 274.49
## - N.Acetylcadaverine 1 7.865 513.81 274.57
## - Oleamide 1 8.131 514.08 274.73
## - T.BIL..uM. 1 8.185 514.13 274.76
## - Salicylic.acid 1 8.366 514.31 274.86
## - Phenylethylamine 1 8.781 514.73 275.10
## - Xanthurenic.acid 1 9.136 515.08 275.30
## - LYMPH.... 1 9.205 515.15 275.34
## - X3.Hydroxyhippuric.acid 1 9.271 515.22 275.38
## - NEUT.... 1 9.733 515.68 275.64
## - Gamma.aminobutyric.acid 1 10.571 516.52 276.11
## - Indoxyl.sulfate 1 10.968 516.92 276.34
## - p.Cresol.sulfate 1 12.819 518.77 277.38
## - S.ganine.1.phosphate_b 1 13.004 518.95 277.49
## - Ascorbic.acid 1 15.006 520.95 278.62
## - Phenyl.sulfate 1 15.444 521.39 278.86
## - X3.Hydroxyanthranilic.acid 1 16.866 522.81 279.66
## - Indole.3.carboxaldehyde 1 17.301 523.25 279.91
## - Kynurenic.acid 1 18.698 524.65 280.69
## - Pantothenol 1 18.993 524.94 280.85
## - AST..U.L. 1 19.047 524.99 280.88
## - X5.Aminopentanoic.acid 1 19.999 525.95 281.41
## - Acetylglycine 1 21.713 527.66 282.37
## - X3..3.Hydroxyphenyl..3.hydroxypropanoic.acid 1 22.658 528.61 282.89
## - X3.Hydroxypropionic.acid 1 26.243 532.19 284.87
## - Indole.3.methyl.acetate 1 27.625 533.57 285.63
## - X1.5.Anhydrosorbitol 1 30.130 536.08 287.00
## - Sphinganine 1 32.106 538.05 288.08
## - HDL.C..mM. 1 33.482 539.43 288.83
## - ALT..U.L. 1 36.501 542.45 290.46
## - Indole.3.acrylic.acid 1 48.904 554.85 297.09
## - Palmitoylethanolamide 1 57.046 562.99 301.36
## - X3.Indolebutyric.acid 1 61.384 567.33 303.61
## - TG..mM. 1 84.292 590.24 315.20
##
## Step: AIC=270.98
## FBG..mM. ~ ALT..U.L. + AST..U.L. + ALB..g.L. + TG..mM. + HDL.C..mM. +
## ALP..U.L. + T.BIL..uM. + D.BIL..uM. + TBA..uM. + NEUT.... +
## LYMPH.... + EO.... + Phenylethylamine + Octadecanamide +
## Urocanic.acid + Imidazolepropionic.acid + Indole.3.carboxaldehyde +
## X3.Hydroxyanthranilic.acid + Oleamide + Palmitoylethanolamide +
## Bilirubin...47 + Indole.3.acrylic.acid + Kynurenic.acid +
## Indole.3.methyl.acetate + Sphinganine + Sphinganine.1.phosphate +
## X3.Indolebutyric.acid + Phenylacetylglutamine.PAGln. + Pantothenol +
## Gamma.aminobutyric.acid + X5.Aminopentanoic.acid + N.Acetylcadaverine +
## Acetylcholine + N.acetyl.aspartic.acid + N8.Acetylspermidine +
## Phenol + X1.5.Anhydrosorbitol + Salicylic.acid + Phenyllactate +
## Bilirubin...82 + X3..3.Hydroxyphenyl..3.hydroxypropanoic.acid +
## p.Cresol.sulfate + X2.Hydroxy.Hippuric.Acid + X3.Hydroxyhippuric.acid +
## S.ganine.1.phosphate_b + Cholesterol.sulfate + Xanthurenic.acid +
## Cinnamoylglycine + Indoxyl.sulfate + Ascorbic.acid + Homovanillic.acid.sulfate +
## Phenyl.sulfate + X3.Hydroxypropionic.acid + Acetylglycine
##
## Df Sum of Sq RSS AIC
## - Acetylcholine 1 1.533 509.08 269.87
## - ALP..U.L. 1 1.636 509.19 269.92
## - TBA..uM. 1 1.879 509.43 270.06
## - Phenol 1 2.606 510.16 270.48
## - Urocanic.acid 1 3.153 510.70 270.80
## - Phenyllactate 1 3.398 510.95 270.94
## <none> 507.55 270.98
## - EO.... 1 3.539 511.09 271.02
## - N.acetyl.aspartic.acid 1 3.648 511.20 271.08
## - Bilirubin...47 1 3.924 511.47 271.24
## - Homovanillic.acid.sulfate 1 3.969 511.52 271.26
## - Sphinganine.1.phosphate 1 4.100 511.65 271.34
## - N8.Acetylspermidine 1 4.676 512.23 271.67
## + Spermine 1 1.603 505.95 272.05
## - X2.Hydroxy.Hippuric.Acid 1 5.394 512.94 272.08
## + Cre..uM. 1 1.521 506.03 272.10
## + X4.Hydroxyphenyllactate 1 1.260 506.29 272.25
## + Spermidine 1 1.231 506.32 272.27
## + Hippuric.acid 1 1.101 506.45 272.35
## - Cinnamoylglycine 1 5.925 513.48 272.38
## - ALB..g.L. 1 5.948 513.50 272.39
## - Imidazolepropionic.acid 1 6.127 513.68 272.50
## + X3.Hydroxybenzoic.acid 1 0.774 506.78 272.53
## - Bilirubin...82 1 6.231 513.78 272.56
## + Iodide 1 0.726 506.82 272.56
## + X4.Hydroxybenzoic.acid.4.O.sulphate 1 0.720 506.83 272.56
## + Biliverdin 1 0.636 506.91 272.61
## - Cholesterol.sulfate 1 6.356 513.91 272.63
## + X4.Hydroxybenzoic.acid 1 0.535 507.02 272.67
## + Oleoylethanolamide 1 0.513 507.04 272.69
## + Stearoylethanolamide 1 0.404 507.15 272.75
## + X4.Hydroxyphenylpropionate 1 0.360 507.19 272.77
## + Sphingosine 1 0.299 507.25 272.81
## + Indole.3.propionic.acid 1 0.298 507.25 272.81
## + X5.Methoxyindoleacetate 1 0.253 507.30 272.83
## + CHE..U.L. 1 0.251 507.30 272.84
## + X3.Hydroxyphenylacetic.acid 1 0.245 507.31 272.84
## + p.Cresol 1 0.236 507.31 272.85
## + X4.Ethylphenyl.sulfate 1 0.234 507.32 272.85
## + Benzoic.acid 1 0.219 507.33 272.85
## + p.Cresol.glucuronide 1 0.214 507.34 272.86
## + Urea..mM. 1 0.191 507.36 272.87
## + Sphingosine.1.phosphate 1 0.188 507.36 272.87
## + TC..mM. 1 0.114 507.44 272.92
## + Dopamine 1 0.106 507.44 272.92
## + Palmitic.amide 1 0.079 507.47 272.94
## + Putrescine 1 0.069 507.48 272.94
## + Dopa 1 0.063 507.49 272.94
## + LDL.C..mM. 1 0.048 507.50 272.95
## + BASO.... 1 0.040 507.51 272.96
## + Enterolactone 1 0.034 507.52 272.96
## + S.gosine.1.phosphate_b 1 0.033 507.52 272.96
## + WBC..10.9.L. 1 0.009 507.54 272.98
## + Υ.GT..U.L. 1 0.001 507.55 272.98
## + UA..uM. 1 0.001 507.55 272.98
## + Phenylacetic.acid 1 0.000 507.55 272.98
## - Phenylacetylglutamine.PAGln. 1 7.143 514.69 273.08
## - Octadecanamide 1 7.250 514.80 273.14
## - Oleamide 1 7.962 515.51 273.54
## - N.Acetylcadaverine 1 8.095 515.65 273.62
## - LYMPH.... 1 8.312 515.86 273.74
## - Salicylic.acid 1 8.376 515.93 273.78
## - D.BIL..uM. 1 8.516 516.07 273.86
## - NEUT.... 1 8.590 516.14 273.90
## - Phenylethylamine 1 8.740 516.29 273.98
## - X3.Hydroxyhippuric.acid 1 9.105 516.66 274.19
## - Xanthurenic.acid 1 9.141 516.69 274.21
## - T.BIL..uM. 1 9.151 516.70 274.22
## - Gamma.aminobutyric.acid 1 10.563 518.11 275.02
## - Indoxyl.sulfate 1 11.135 518.69 275.34
## - p.Cresol.sulfate 1 12.735 520.29 276.24
## - S.ganine.1.phosphate_b 1 13.389 520.94 276.61
## - Phenyl.sulfate 1 15.172 522.72 277.61
## - Ascorbic.acid 1 16.251 523.80 278.21
## - X3.Hydroxyanthranilic.acid 1 16.631 524.18 278.43
## - Indole.3.carboxaldehyde 1 17.484 525.03 278.90
## - Pantothenol 1 19.240 526.79 279.88
## - Kynurenic.acid 1 19.346 526.90 279.94
## - X5.Aminopentanoic.acid 1 19.796 527.35 280.19
## - AST..U.L. 1 20.226 527.78 280.43
## - Acetylglycine 1 21.275 528.83 281.01
## - X3..3.Hydroxyphenyl..3.hydroxypropanoic.acid 1 22.208 529.76 281.53
## - X3.Hydroxypropionic.acid 1 24.858 532.41 282.99
## - Indole.3.methyl.acetate 1 27.658 535.21 284.53
## - Sphinganine 1 30.746 538.30 286.21
## - X1.5.Anhydrosorbitol 1 32.692 540.24 287.27
## - HDL.C..mM. 1 35.427 542.98 288.75
## - ALT..U.L. 1 37.316 544.87 289.77
## - Indole.3.acrylic.acid 1 48.307 555.86 295.62
## - Palmitoylethanolamide 1 58.720 566.27 301.06
## - X3.Indolebutyric.acid 1 60.141 567.69 301.79
## - TG..mM. 1 85.026 592.58 314.36
##
## Step: AIC=269.87
## FBG..mM. ~ ALT..U.L. + AST..U.L. + ALB..g.L. + TG..mM. + HDL.C..mM. +
## ALP..U.L. + T.BIL..uM. + D.BIL..uM. + TBA..uM. + NEUT.... +
## LYMPH.... + EO.... + Phenylethylamine + Octadecanamide +
## Urocanic.acid + Imidazolepropionic.acid + Indole.3.carboxaldehyde +
## X3.Hydroxyanthranilic.acid + Oleamide + Palmitoylethanolamide +
## Bilirubin...47 + Indole.3.acrylic.acid + Kynurenic.acid +
## Indole.3.methyl.acetate + Sphinganine + Sphinganine.1.phosphate +
## X3.Indolebutyric.acid + Phenylacetylglutamine.PAGln. + Pantothenol +
## Gamma.aminobutyric.acid + X5.Aminopentanoic.acid + N.Acetylcadaverine +
## N.acetyl.aspartic.acid + N8.Acetylspermidine + Phenol + X1.5.Anhydrosorbitol +
## Salicylic.acid + Phenyllactate + Bilirubin...82 + X3..3.Hydroxyphenyl..3.hydroxypropanoic.acid +
## p.Cresol.sulfate + X2.Hydroxy.Hippuric.Acid + X3.Hydroxyhippuric.acid +
## S.ganine.1.phosphate_b + Cholesterol.sulfate + Xanthurenic.acid +
## Cinnamoylglycine + Indoxyl.sulfate + Ascorbic.acid + Homovanillic.acid.sulfate +
## Phenyl.sulfate + X3.Hydroxypropionic.acid + Acetylglycine
##
## Df Sum of Sq RSS AIC
## - ALP..U.L. 1 1.547 510.63 268.75
## - TBA..uM. 1 1.823 510.91 268.91
## - Phenol 1 2.731 511.81 269.43
## - Urocanic.acid 1 2.933 512.02 269.55
## - N.acetyl.aspartic.acid 1 3.092 512.18 269.64
## - EO.... 1 3.339 512.42 269.78
## - Bilirubin...47 1 3.451 512.54 269.85
## <none> 509.08 269.87
## - Homovanillic.acid.sulfate 1 3.709 512.79 269.99
## - Sphinganine.1.phosphate 1 4.018 513.10 270.17
## - Phenyllactate 1 4.418 513.50 270.40
## - X2.Hydroxy.Hippuric.Acid 1 4.982 514.07 270.72
## - Cinnamoylglycine 1 5.377 514.46 270.94
## + Acetylcholine 1 1.533 507.55 270.98
## - N8.Acetylspermidine 1 5.507 514.59 271.02
## + Cre..uM. 1 1.391 507.69 271.06
## - Bilirubin...82 1 5.768 514.85 271.17
## + Spermine 1 1.199 507.88 271.17
## + Hippuric.acid 1 1.126 507.96 271.22
## + X4.Hydroxyphenyllactate 1 1.114 507.97 271.22
## + X3.Hydroxybenzoic.acid 1 1.046 508.04 271.26
## - Imidazolepropionic.acid 1 6.013 515.10 271.31
## + Spermidine 1 0.764 508.32 271.43
## + Iodide 1 0.644 508.44 271.49
## + Biliverdin 1 0.597 508.49 271.52
## + X4.Hydroxybenzoic.acid.4.O.sulphate 1 0.562 508.52 271.54
## - Cholesterol.sulfate 1 6.451 515.53 271.56
## + X4.Hydroxybenzoic.acid 1 0.456 508.63 271.60
## + p.Cresol 1 0.416 508.67 271.63
## + Sphingosine 1 0.353 508.73 271.66
## + Dopa 1 0.348 508.74 271.67
## + Indole.3.propionic.acid 1 0.332 508.75 271.67
## + X4.Hydroxyphenylpropionate 1 0.332 508.75 271.67
## + X3.Hydroxyphenylacetic.acid 1 0.326 508.76 271.68
## + Stearoylethanolamide 1 0.325 508.76 271.68
## + Oleoylethanolamide 1 0.324 508.76 271.68
## + Benzoic.acid 1 0.289 508.80 271.70
## + Dopamine 1 0.263 508.82 271.71
## + X4.Ethylphenyl.sulfate 1 0.230 508.85 271.73
## - ALB..g.L. 1 6.768 515.85 271.74
## + TC..mM. 1 0.202 508.88 271.75
## + p.Cresol.glucuronide 1 0.146 508.94 271.78
## + Urea..mM. 1 0.145 508.94 271.78
## + X5.Methoxyindoleacetate 1 0.140 508.94 271.79
## + CHE..U.L. 1 0.111 508.97 271.80
## + Sphingosine.1.phosphate 1 0.093 508.99 271.81
## + Palmitic.amide 1 0.074 509.01 271.82
## + WBC..10.9.L. 1 0.051 509.03 271.84
## + BASO.... 1 0.047 509.04 271.84
## + LDL.C..mM. 1 0.034 509.05 271.85
## + Enterolactone 1 0.026 509.06 271.85
## + S.gosine.1.phosphate_b 1 0.012 509.07 271.86
## + Phenylacetic.acid 1 0.004 509.08 271.86
## + Υ.GT..U.L. 1 0.004 509.08 271.86
## + UA..uM. 1 0.002 509.08 271.86
## + Putrescine 1 0.000 509.08 271.87
## - Phenylacetylglutamine.PAGln. 1 7.122 516.21 271.94
## - Octadecanamide 1 7.192 516.28 271.98
## - Oleamide 1 7.733 516.82 272.28
## - Salicylic.acid 1 7.997 517.08 272.43
## - LYMPH.... 1 8.140 517.22 272.51
## - NEUT.... 1 8.417 517.50 272.67
## - N.Acetylcadaverine 1 8.436 517.52 272.68
## - D.BIL..uM. 1 8.998 518.08 273.00
## - X3.Hydroxyhippuric.acid 1 9.561 518.64 273.32
## - Phenylethylamine 1 9.601 518.68 273.34
## - T.BIL..uM. 1 9.694 518.78 273.39
## - Xanthurenic.acid 1 10.484 519.57 273.84
## - Indoxyl.sulfate 1 11.359 520.44 274.33
## - Gamma.aminobutyric.acid 1 11.655 520.74 274.50
## - p.Cresol.sulfate 1 12.479 521.56 274.96
## - S.ganine.1.phosphate_b 1 13.105 522.19 275.31
## - Phenyl.sulfate 1 14.295 523.38 275.98
## - X3.Hydroxyanthranilic.acid 1 15.459 524.54 276.63
## - Ascorbic.acid 1 16.662 525.75 277.30
## - Indole.3.carboxaldehyde 1 17.855 526.94 277.96
## - Kynurenic.acid 1 18.239 527.32 278.18
## - X5.Aminopentanoic.acid 1 18.473 527.56 278.31
## - Pantothenol 1 18.692 527.78 278.43
## - Acetylglycine 1 19.755 528.84 279.02
## - AST..U.L. 1 20.608 529.69 279.49
## - X3..3.Hydroxyphenyl..3.hydroxypropanoic.acid 1 23.409 532.49 281.04
## - X3.Hydroxypropionic.acid 1 24.341 533.42 281.55
## - Indole.3.methyl.acetate 1 28.698 537.78 283.93
## - Sphinganine 1 29.568 538.65 284.41
## - X1.5.Anhydrosorbitol 1 34.405 543.49 287.03
## - HDL.C..mM. 1 34.462 543.55 287.06
## - ALT..U.L. 1 38.289 547.37 289.11
## - Indole.3.acrylic.acid 1 49.605 558.69 295.11
## - X3.Indolebutyric.acid 1 61.277 570.36 301.17
## - Palmitoylethanolamide 1 63.977 573.06 302.55
## - TG..mM. 1 83.522 592.61 312.38
##
## Step: AIC=268.75
## FBG..mM. ~ ALT..U.L. + AST..U.L. + ALB..g.L. + TG..mM. + HDL.C..mM. +
## T.BIL..uM. + D.BIL..uM. + TBA..uM. + NEUT.... + LYMPH.... +
## EO.... + Phenylethylamine + Octadecanamide + Urocanic.acid +
## Imidazolepropionic.acid + Indole.3.carboxaldehyde + X3.Hydroxyanthranilic.acid +
## Oleamide + Palmitoylethanolamide + Bilirubin...47 + Indole.3.acrylic.acid +
## Kynurenic.acid + Indole.3.methyl.acetate + Sphinganine +
## Sphinganine.1.phosphate + X3.Indolebutyric.acid + Phenylacetylglutamine.PAGln. +
## Pantothenol + Gamma.aminobutyric.acid + X5.Aminopentanoic.acid +
## N.Acetylcadaverine + N.acetyl.aspartic.acid + N8.Acetylspermidine +
## Phenol + X1.5.Anhydrosorbitol + Salicylic.acid + Phenyllactate +
## Bilirubin...82 + X3..3.Hydroxyphenyl..3.hydroxypropanoic.acid +
## p.Cresol.sulfate + X2.Hydroxy.Hippuric.Acid + X3.Hydroxyhippuric.acid +
## S.ganine.1.phosphate_b + Cholesterol.sulfate + Xanthurenic.acid +
## Cinnamoylglycine + Indoxyl.sulfate + Ascorbic.acid + Homovanillic.acid.sulfate +
## Phenyl.sulfate + X3.Hydroxypropionic.acid + Acetylglycine
##
## Df Sum of Sq RSS AIC
## - TBA..uM. 1 1.418 512.05 267.57
## - Urocanic.acid 1 2.854 513.48 268.39
## - Phenol 1 3.122 513.75 268.54
## - EO.... 1 3.293 513.92 268.64
## - N.acetyl.aspartic.acid 1 3.298 513.93 268.64
## - Bilirubin...47 1 3.318 513.95 268.65
## <none> 510.63 268.75
## - Sphinganine.1.phosphate 1 4.179 514.81 269.14
## - Homovanillic.acid.sulfate 1 4.780 515.41 269.48
## - X2.Hydroxy.Hippuric.Acid 1 5.073 515.70 269.65
## - Phenyllactate 1 5.448 516.08 269.86
## + ALP..U.L. 1 1.547 509.08 269.87
## - Cholesterol.sulfate 1 5.466 516.10 269.87
## - N8.Acetylspermidine 1 5.510 516.14 269.90
## + Acetylcholine 1 1.444 509.19 269.92
## - Bilirubin...82 1 5.701 516.33 270.01
## - Imidazolepropionic.acid 1 5.747 516.38 270.03
## + Spermine 1 1.196 509.43 270.07
## + Cre..uM. 1 1.189 509.44 270.07
## - Cinnamoylglycine 1 5.826 516.46 270.08
## + Hippuric.acid 1 1.089 509.54 270.13
## + X3.Hydroxybenzoic.acid 1 0.883 509.75 270.25
## + X4.Hydroxyphenyllactate 1 0.873 509.76 270.25
## + Spermidine 1 0.723 509.91 270.34
## + Iodide 1 0.695 509.94 270.36
## + Biliverdin 1 0.663 509.97 270.37
## + X4.Hydroxybenzoic.acid.4.O.sulphate 1 0.460 510.17 270.49
## + p.Cresol 1 0.439 510.19 270.50
## + Dopa 1 0.424 510.21 270.51
## + X3.Hydroxyphenylacetic.acid 1 0.400 510.23 270.52
## + X4.Hydroxyphenylpropionate 1 0.386 510.24 270.53
## + Oleoylethanolamide 1 0.345 510.29 270.56
## + Indole.3.propionic.acid 1 0.331 510.30 270.56
## + X4.Hydroxybenzoic.acid 1 0.331 510.30 270.56
## + X4.Ethylphenyl.sulfate 1 0.307 510.32 270.58
## + Stearoylethanolamide 1 0.273 510.36 270.60
## + X5.Methoxyindoleacetate 1 0.266 510.36 270.60
## + Benzoic.acid 1 0.229 510.40 270.62
## + CHE..U.L. 1 0.217 510.41 270.63
## + Sphingosine 1 0.214 510.42 270.63
## + LDL.C..mM. 1 0.209 510.42 270.63
## + p.Cresol.glucuronide 1 0.161 510.47 270.66
## + Dopamine 1 0.152 510.48 270.67
## + TC..mM. 1 0.105 510.53 270.69
## - Phenylacetylglutamine.PAGln. 1 6.950 517.58 270.71
## + Palmitic.amide 1 0.045 510.59 270.73
## + Sphingosine.1.phosphate 1 0.032 510.60 270.74
## + WBC..10.9.L. 1 0.022 510.61 270.74
## + Putrescine 1 0.015 510.62 270.75
## + Urea..mM. 1 0.014 510.62 270.75
## + S.gosine.1.phosphate_b 1 0.010 510.62 270.75
## + Υ.GT..U.L. 1 0.007 510.62 270.75
## + Enterolactone 1 0.006 510.62 270.75
## + UA..uM. 1 0.004 510.63 270.75
## + Phenylacetic.acid 1 0.000 510.63 270.75
## + BASO.... 1 0.000 510.63 270.75
## - Octadecanamide 1 7.496 518.13 271.02
## - ALB..g.L. 1 7.657 518.29 271.12
## - Oleamide 1 7.926 518.56 271.27
## - N.Acetylcadaverine 1 8.144 518.77 271.39
## - D.BIL..uM. 1 8.276 518.91 271.46
## - Salicylic.acid 1 8.431 519.06 271.55
## - NEUT.... 1 8.481 519.11 271.58
## - LYMPH.... 1 8.812 519.44 271.77
## - X3.Hydroxyhippuric.acid 1 9.014 519.64 271.88
## - T.BIL..uM. 1 9.156 519.79 271.96
## - Phenylethylamine 1 9.895 520.53 272.38
## - Gamma.aminobutyric.acid 1 11.072 521.70 273.04
## - Xanthurenic.acid 1 11.278 521.91 273.15
## - Indoxyl.sulfate 1 11.874 522.50 273.49
## - p.Cresol.sulfate 1 11.924 522.55 273.52
## - S.ganine.1.phosphate_b 1 14.206 524.84 274.79
## - X3.Hydroxyanthranilic.acid 1 14.354 524.98 274.88
## - Phenyl.sulfate 1 14.964 525.59 275.22
## - X5.Aminopentanoic.acid 1 17.401 528.03 276.57
## - Indole.3.carboxaldehyde 1 18.147 528.78 276.99
## - Ascorbic.acid 1 18.314 528.94 277.08
## - Kynurenic.acid 1 18.985 529.62 277.45
## - Pantothenol 1 19.071 529.70 277.50
## - AST..U.L. 1 21.584 532.21 278.88
## - Acetylglycine 1 21.674 532.30 278.93
## - X3..3.Hydroxyphenyl..3.hydroxypropanoic.acid 1 22.677 533.31 279.49
## - X3.Hydroxypropionic.acid 1 24.640 535.27 280.56
## - Indole.3.methyl.acetate 1 29.274 539.90 283.09
## - Sphinganine 1 30.658 541.29 283.84
## - X1.5.Anhydrosorbitol 1 33.696 544.33 285.48
## - HDL.C..mM. 1 34.198 544.83 285.75
## - ALT..U.L. 1 39.531 550.16 288.60
## - Indole.3.acrylic.acid 1 50.217 560.85 294.24
## - X3.Indolebutyric.acid 1 60.570 571.20 299.60
## - Palmitoylethanolamide 1 62.462 573.09 300.57
## - TG..mM. 1 84.039 594.67 311.39
##
## Step: AIC=267.57
## FBG..mM. ~ ALT..U.L. + AST..U.L. + ALB..g.L. + TG..mM. + HDL.C..mM. +
## T.BIL..uM. + D.BIL..uM. + NEUT.... + LYMPH.... + EO.... +
## Phenylethylamine + Octadecanamide + Urocanic.acid + Imidazolepropionic.acid +
## Indole.3.carboxaldehyde + X3.Hydroxyanthranilic.acid + Oleamide +
## Palmitoylethanolamide + Bilirubin...47 + Indole.3.acrylic.acid +
## Kynurenic.acid + Indole.3.methyl.acetate + Sphinganine +
## Sphinganine.1.phosphate + X3.Indolebutyric.acid + Phenylacetylglutamine.PAGln. +
## Pantothenol + Gamma.aminobutyric.acid + X5.Aminopentanoic.acid +
## N.Acetylcadaverine + N.acetyl.aspartic.acid + N8.Acetylspermidine +
## Phenol + X1.5.Anhydrosorbitol + Salicylic.acid + Phenyllactate +
## Bilirubin...82 + X3..3.Hydroxyphenyl..3.hydroxypropanoic.acid +
## p.Cresol.sulfate + X2.Hydroxy.Hippuric.Acid + X3.Hydroxyhippuric.acid +
## S.ganine.1.phosphate_b + Cholesterol.sulfate + Xanthurenic.acid +
## Cinnamoylglycine + Indoxyl.sulfate + Ascorbic.acid + Homovanillic.acid.sulfate +
## Phenyl.sulfate + X3.Hydroxypropionic.acid + Acetylglycine
##
## Df Sum of Sq RSS AIC
## - Urocanic.acid 1 2.723 514.77 267.12
## - EO.... 1 2.865 514.91 267.20
## - N.acetyl.aspartic.acid 1 2.954 515.00 267.25
## - Phenol 1 3.101 515.15 267.33
## - Bilirubin...47 1 3.466 515.51 267.54
## <none> 512.05 267.57
## - Homovanillic.acid.sulfate 1 4.735 516.78 268.26
## - X2.Hydroxy.Hippuric.Acid 1 4.989 517.04 268.41
## - Sphinganine.1.phosphate 1 5.108 517.16 268.48
## - Imidazolepropionic.acid 1 5.224 517.27 268.54
## + TBA..uM. 1 1.418 510.63 268.75
## + Acetylcholine 1 1.408 510.64 268.76
## - Cholesterol.sulfate 1 5.645 517.69 268.78
## + Spermine 1 1.252 510.80 268.85
## + Cre..uM. 1 1.241 510.81 268.86
## + ALP..U.L. 1 1.141 510.91 268.91
## - N8.Acetylspermidine 1 5.924 517.97 268.94
## + Hippuric.acid 1 1.066 510.98 268.96
## - Phenyllactate 1 6.031 518.08 269.00
## + Iodide 1 0.921 511.13 269.04
## - Bilirubin...82 1 6.171 518.22 269.08
## - Cinnamoylglycine 1 6.213 518.26 269.10
## - Phenylacetylglutamine.PAGln. 1 6.294 518.34 269.15
## + X3.Hydroxybenzoic.acid 1 0.656 511.39 269.19
## + X4.Hydroxyphenyllactate 1 0.600 511.45 269.22
## + Spermidine 1 0.553 511.50 269.25
## + Biliverdin 1 0.466 511.58 269.30
## + X4.Hydroxyphenylpropionate 1 0.456 511.59 269.31
## + p.Cresol 1 0.447 511.60 269.31
## + X4.Hydroxybenzoic.acid.4.O.sulphate 1 0.413 511.64 269.33
## + X4.Hydroxybenzoic.acid 1 0.380 511.67 269.35
## + X3.Hydroxyphenylacetic.acid 1 0.376 511.67 269.35
## + Dopa 1 0.336 511.71 269.37
## + Indole.3.propionic.acid 1 0.308 511.74 269.39
## + X5.Methoxyindoleacetate 1 0.260 511.79 269.42
## + Sphingosine 1 0.235 511.81 269.43
## + LDL.C..mM. 1 0.209 511.84 269.45
## + CHE..U.L. 1 0.184 511.86 269.46
## + Oleoylethanolamide 1 0.173 511.88 269.47
## + Benzoic.acid 1 0.169 511.88 269.47
## + Stearoylethanolamide 1 0.150 511.90 269.48
## + p.Cresol.glucuronide 1 0.147 511.90 269.48
## + X4.Ethylphenyl.sulfate 1 0.139 511.91 269.49
## + Dopamine 1 0.137 511.91 269.49
## + TC..mM. 1 0.135 511.91 269.49
## + WBC..10.9.L. 1 0.101 511.95 269.51
## + Palmitic.amide 1 0.026 512.02 269.55
## + Urea..mM. 1 0.021 512.03 269.55
## + Enterolactone 1 0.013 512.04 269.56
## + S.gosine.1.phosphate_b 1 0.012 512.04 269.56
## + Sphingosine.1.phosphate 1 0.010 512.04 269.56
## + Putrescine 1 0.004 512.04 269.56
## + UA..uM. 1 0.003 512.05 269.56
## + BASO.... 1 0.002 512.05 269.56
## + Υ.GT..U.L. 1 0.001 512.05 269.57
## + Phenylacetic.acid 1 0.000 512.05 269.57
## - ALB..g.L. 1 7.310 519.36 269.72
## - Octadecanamide 1 7.621 519.67 269.89
## - Oleamide 1 7.668 519.72 269.92
## - NEUT.... 1 7.961 520.01 270.09
## - Salicylic.acid 1 8.178 520.23 270.21
## - D.BIL..uM. 1 8.520 520.57 270.40
## - LYMPH.... 1 8.582 520.63 270.44
## - X3.Hydroxyhippuric.acid 1 8.995 521.04 270.67
## - T.BIL..uM. 1 9.385 521.43 270.89
## - Phenylethylamine 1 9.862 521.91 271.16
## - N.Acetylcadaverine 1 9.955 522.00 271.21
## - Gamma.aminobutyric.acid 1 10.269 522.32 271.38
## - Xanthurenic.acid 1 11.018 523.07 271.80
## - Indoxyl.sulfate 1 11.495 523.54 272.07
## - p.Cresol.sulfate 1 12.295 524.34 272.52
## - X3.Hydroxyanthranilic.acid 1 14.824 526.87 273.93
## - Phenyl.sulfate 1 15.029 527.08 274.04
## - S.ganine.1.phosphate_b 1 16.295 528.34 274.75
## - X5.Aminopentanoic.acid 1 16.829 528.88 275.04
## - Indole.3.carboxaldehyde 1 17.501 529.55 275.41
## - Ascorbic.acid 1 18.197 530.25 275.80
## - Pantothenol 1 18.556 530.61 276.00
## - Acetylglycine 1 20.826 532.87 277.25
## - Kynurenic.acid 1 21.854 533.90 277.81
## - AST..U.L. 1 22.940 534.99 278.41
## - X3..3.Hydroxyphenyl..3.hydroxypropanoic.acid 1 23.209 535.26 278.56
## - X3.Hydroxypropionic.acid 1 24.444 536.49 279.23
## - Indole.3.methyl.acetate 1 28.663 540.71 281.52
## - Sphinganine 1 31.083 543.13 282.83
## - X1.5.Anhydrosorbitol 1 32.883 544.93 283.80
## - HDL.C..mM. 1 35.037 547.09 284.96
## - ALT..U.L. 1 39.989 552.04 287.60
## - Indole.3.acrylic.acid 1 49.460 561.51 292.58
## - X3.Indolebutyric.acid 1 59.216 571.26 297.63
## - Palmitoylethanolamide 1 61.511 573.56 298.81
## - TG..mM. 1 83.415 595.46 309.79
##
## Step: AIC=267.12
## FBG..mM. ~ ALT..U.L. + AST..U.L. + ALB..g.L. + TG..mM. + HDL.C..mM. +
## T.BIL..uM. + D.BIL..uM. + NEUT.... + LYMPH.... + EO.... +
## Phenylethylamine + Octadecanamide + Imidazolepropionic.acid +
## Indole.3.carboxaldehyde + X3.Hydroxyanthranilic.acid + Oleamide +
## Palmitoylethanolamide + Bilirubin...47 + Indole.3.acrylic.acid +
## Kynurenic.acid + Indole.3.methyl.acetate + Sphinganine +
## Sphinganine.1.phosphate + X3.Indolebutyric.acid + Phenylacetylglutamine.PAGln. +
## Pantothenol + Gamma.aminobutyric.acid + X5.Aminopentanoic.acid +
## N.Acetylcadaverine + N.acetyl.aspartic.acid + N8.Acetylspermidine +
## Phenol + X1.5.Anhydrosorbitol + Salicylic.acid + Phenyllactate +
## Bilirubin...82 + X3..3.Hydroxyphenyl..3.hydroxypropanoic.acid +
## p.Cresol.sulfate + X2.Hydroxy.Hippuric.Acid + X3.Hydroxyhippuric.acid +
## S.ganine.1.phosphate_b + Cholesterol.sulfate + Xanthurenic.acid +
## Cinnamoylglycine + Indoxyl.sulfate + Ascorbic.acid + Homovanillic.acid.sulfate +
## Phenyl.sulfate + X3.Hydroxypropionic.acid + Acetylglycine
##
## Df Sum of Sq RSS AIC
## - N.acetyl.aspartic.acid 1 2.839 517.61 266.73
## - Phenol 1 2.932 517.70 266.78
## - EO.... 1 3.404 518.18 267.05
## <none> 514.77 267.12
## - Bilirubin...47 1 4.167 518.94 267.48
## + Urocanic.acid 1 2.723 512.05 267.57
## - Sphinganine.1.phosphate 1 5.113 519.89 268.02
## - X2.Hydroxy.Hippuric.Acid 1 5.182 519.95 268.06
## - Homovanillic.acid.sulfate 1 5.195 519.97 268.06
## - Imidazolepropionic.acid 1 5.212 519.98 268.07
## + Cre..uM. 1 1.764 513.01 268.12
## - Cinnamoylglycine 1 5.531 520.30 268.25
## - N8.Acetylspermidine 1 5.718 520.49 268.36
## + Spermine 1 1.297 513.47 268.38
## + TBA..uM. 1 1.288 513.48 268.39
## + Acetylcholine 1 1.208 513.56 268.43
## - Phenyllactate 1 5.957 520.73 268.49
## + Iodide 1 1.101 513.67 268.49
## + ALP..U.L. 1 1.092 513.68 268.50
## - Cholesterol.sulfate 1 5.971 520.74 268.50
## + Hippuric.acid 1 1.010 513.76 268.55
## + X4.Hydroxyphenyllactate 1 0.777 513.99 268.68
## + X3.Hydroxybenzoic.acid 1 0.699 514.07 268.72
## + X4.Hydroxyphenylpropionate 1 0.564 514.21 268.80
## + Spermidine 1 0.548 514.22 268.81
## + p.Cresol 1 0.513 514.26 268.83
## + Dopa 1 0.504 514.27 268.83
## + X4.Hydroxybenzoic.acid 1 0.493 514.28 268.84
## + X3.Hydroxyphenylacetic.acid 1 0.406 514.37 268.89
## + Biliverdin 1 0.384 514.39 268.90
## + X4.Hydroxybenzoic.acid.4.O.sulphate 1 0.382 514.39 268.90
## + X5.Methoxyindoleacetate 1 0.369 514.40 268.91
## - Bilirubin...82 1 6.750 521.52 268.94
## + Indole.3.propionic.acid 1 0.300 514.47 268.95
## + LDL.C..mM. 1 0.264 514.51 268.97
## + CHE..U.L. 1 0.192 514.58 269.01
## + Sphingosine 1 0.191 514.58 269.01
## + Oleoylethanolamide 1 0.175 514.60 269.02
## + p.Cresol.glucuronide 1 0.158 514.61 269.03
## + Dopamine 1 0.146 514.63 269.04
## + Stearoylethanolamide 1 0.141 514.63 269.04
## + TC..mM. 1 0.138 514.63 269.04
## + Palmitic.amide 1 0.122 514.65 269.05
## + WBC..10.9.L. 1 0.113 514.66 269.06
## - Phenylacetylglutamine.PAGln. 1 7.003 521.77 269.08
## + Benzoic.acid 1 0.070 514.70 269.08
## + X4.Ethylphenyl.sulfate 1 0.068 514.70 269.08
## + Urea..mM. 1 0.043 514.73 269.10
## + Sphingosine.1.phosphate 1 0.012 514.76 269.11
## + BASO.... 1 0.012 514.76 269.11
## + Enterolactone 1 0.011 514.76 269.11
## + UA..uM. 1 0.005 514.77 269.12
## + Υ.GT..U.L. 1 0.002 514.77 269.12
## + Putrescine 1 0.001 514.77 269.12
## + S.gosine.1.phosphate_b 1 0.000 514.77 269.12
## + Phenylacetic.acid 1 0.000 514.77 269.12
## - ALB..g.L. 1 7.378 522.15 269.29
## - NEUT.... 1 7.910 522.68 269.59
## - Octadecanamide 1 8.202 522.97 269.75
## - Salicylic.acid 1 8.380 523.15 269.85
## - Oleamide 1 8.645 523.42 270.00
## - D.BIL..uM. 1 8.711 523.48 270.04
## - LYMPH.... 1 8.939 523.71 270.17
## - Phenylethylamine 1 9.193 523.96 270.31
## - X3.Hydroxyhippuric.acid 1 9.560 524.33 270.51
## - N.Acetylcadaverine 1 9.571 524.34 270.52
## - T.BIL..uM. 1 9.747 524.52 270.62
## - Xanthurenic.acid 1 10.460 525.23 271.01
## - Gamma.aminobutyric.acid 1 10.541 525.31 271.06
## - Indoxyl.sulfate 1 11.313 526.08 271.49
## - p.Cresol.sulfate 1 13.303 528.08 272.60
## - X3.Hydroxyanthranilic.acid 1 13.890 528.66 272.92
## - S.ganine.1.phosphate_b 1 15.731 530.50 273.94
## - X5.Aminopentanoic.acid 1 16.220 530.99 274.21
## - Phenyl.sulfate 1 16.384 531.16 274.30
## - Ascorbic.acid 1 17.199 531.97 274.75
## - Indole.3.carboxaldehyde 1 17.661 532.43 275.00
## - Pantothenol 1 18.132 532.90 275.26
## - Acetylglycine 1 21.044 535.82 276.86
## - Kynurenic.acid 1 23.043 537.81 277.95
## - AST..U.L. 1 23.314 538.09 278.10
## - X3..3.Hydroxyphenyl..3.hydroxypropanoic.acid 1 24.361 539.13 278.67
## - X3.Hydroxypropionic.acid 1 24.886 539.66 278.95
## - Indole.3.methyl.acetate 1 30.471 545.24 281.97
## - Sphinganine 1 30.566 545.34 282.02
## - X1.5.Anhydrosorbitol 1 31.201 545.97 282.36
## - HDL.C..mM. 1 35.311 550.08 284.56
## - ALT..U.L. 1 40.450 555.22 287.28
## - Indole.3.acrylic.acid 1 51.849 566.62 293.24
## - X3.Indolebutyric.acid 1 57.187 571.96 295.99
## - Palmitoylethanolamide 1 62.212 576.98 298.55
## - TG..mM. 1 83.685 598.46 309.25
##
## Step: AIC=266.73
## FBG..mM. ~ ALT..U.L. + AST..U.L. + ALB..g.L. + TG..mM. + HDL.C..mM. +
## T.BIL..uM. + D.BIL..uM. + NEUT.... + LYMPH.... + EO.... +
## Phenylethylamine + Octadecanamide + Imidazolepropionic.acid +
## Indole.3.carboxaldehyde + X3.Hydroxyanthranilic.acid + Oleamide +
## Palmitoylethanolamide + Bilirubin...47 + Indole.3.acrylic.acid +
## Kynurenic.acid + Indole.3.methyl.acetate + Sphinganine +
## Sphinganine.1.phosphate + X3.Indolebutyric.acid + Phenylacetylglutamine.PAGln. +
## Pantothenol + Gamma.aminobutyric.acid + X5.Aminopentanoic.acid +
## N.Acetylcadaverine + N8.Acetylspermidine + Phenol + X1.5.Anhydrosorbitol +
## Salicylic.acid + Phenyllactate + Bilirubin...82 + X3..3.Hydroxyphenyl..3.hydroxypropanoic.acid +
## p.Cresol.sulfate + X2.Hydroxy.Hippuric.Acid + X3.Hydroxyhippuric.acid +
## S.ganine.1.phosphate_b + Cholesterol.sulfate + Xanthurenic.acid +
## Cinnamoylglycine + Indoxyl.sulfate + Ascorbic.acid + Homovanillic.acid.sulfate +
## Phenyl.sulfate + X3.Hydroxypropionic.acid + Acetylglycine
##
## Df Sum of Sq RSS AIC
## - Phenol 1 2.762 520.37 266.29
## <none> 517.61 266.73
## - EO.... 1 3.545 521.16 266.73
## - Bilirubin...47 1 3.811 521.42 266.88
## + N.acetyl.aspartic.acid 1 2.839 514.77 267.12
## + Urocanic.acid 1 2.608 515.00 267.25
## - Sphinganine.1.phosphate 1 5.306 522.92 267.72
## + Spermine 1 1.783 515.83 267.72
## - Imidazolepropionic.acid 1 5.399 523.01 267.77
## - X2.Hydroxy.Hippuric.Acid 1 5.517 523.13 267.84
## - Cholesterol.sulfate 1 5.763 523.37 267.98
## + ALP..U.L. 1 1.297 516.31 268.00
## + Iodide 1 1.197 516.41 268.05
## - Cinnamoylglycine 1 5.979 523.59 268.10
## - Homovanillic.acid.sulfate 1 6.101 523.71 268.17
## + Hippuric.acid 1 0.994 516.62 268.17
## + TBA..uM. 1 0.970 516.64 268.18
## - N8.Acetylspermidine 1 6.208 523.82 268.23
## + X3.Hydroxybenzoic.acid 1 0.880 516.73 268.23
## + X3.Hydroxyphenylacetic.acid 1 0.780 516.83 268.29
## + Acetylcholine 1 0.742 516.87 268.31
## + X4.Hydroxyphenyllactate 1 0.651 516.96 268.36
## - Phenyllactate 1 6.457 524.07 268.36
## + Spermidine 1 0.571 517.04 268.41
## + X4.Hydroxybenzoic.acid 1 0.556 517.05 268.42
## + Cre..uM. 1 0.490 517.12 268.45
## + p.Cresol 1 0.446 517.16 268.48
## + Indole.3.propionic.acid 1 0.423 517.19 268.49
## + X4.Hydroxyphenylpropionate 1 0.350 517.26 268.53
## + X5.Methoxyindoleacetate 1 0.331 517.28 268.54
## + LDL.C..mM. 1 0.324 517.29 268.55
## + X4.Hydroxybenzoic.acid.4.O.sulphate 1 0.259 517.35 268.58
## + Biliverdin 1 0.257 517.35 268.59
## + CHE..U.L. 1 0.232 517.38 268.60
## + Dopamine 1 0.198 517.41 268.62
## + TC..mM. 1 0.176 517.43 268.63
## + Dopa 1 0.163 517.45 268.64
## + Benzoic.acid 1 0.159 517.45 268.64
## + Oleoylethanolamide 1 0.138 517.47 268.65
## + p.Cresol.glucuronide 1 0.124 517.49 268.66
## + Sphingosine 1 0.092 517.52 268.68
## + WBC..10.9.L. 1 0.088 517.52 268.68
## + BASO.... 1 0.076 517.53 268.69
## + Stearoylethanolamide 1 0.069 517.54 268.69
## + Palmitic.amide 1 0.066 517.54 268.69
## + Enterolactone 1 0.044 517.57 268.71
## + Sphingosine.1.phosphate 1 0.031 517.58 268.71
## + Υ.GT..U.L. 1 0.021 517.59 268.72
## + Urea..mM. 1 0.017 517.59 268.72
## + Putrescine 1 0.016 517.59 268.72
## - Bilirubin...82 1 7.100 524.71 268.72
## + Phenylacetic.acid 1 0.001 517.61 268.73
## + UA..uM. 1 0.001 517.61 268.73
## + X4.Ethylphenyl.sulfate 1 0.000 517.61 268.73
## + S.gosine.1.phosphate_b 1 0.000 517.61 268.73
## - ALB..g.L. 1 7.314 524.92 268.84
## - Octadecanamide 1 7.621 525.23 269.01
## - Phenylacetylglutamine.PAGln. 1 7.797 525.41 269.11
## - Oleamide 1 8.189 525.80 269.33
## - Salicylic.acid 1 8.495 526.11 269.50
## - Phenylethylamine 1 9.138 526.75 269.86
## - NEUT.... 1 9.272 526.88 269.93
## - X3.Hydroxyhippuric.acid 1 9.602 527.21 270.12
## - N.Acetylcadaverine 1 9.661 527.27 270.15
## - Xanthurenic.acid 1 10.029 527.64 270.36
## - LYMPH.... 1 10.306 527.92 270.51
## - D.BIL..uM. 1 10.596 528.21 270.67
## - Gamma.aminobutyric.acid 1 11.129 528.74 270.96
## - Indoxyl.sulfate 1 11.683 529.29 271.27
## - T.BIL..uM. 1 11.690 529.30 271.27
## - X3.Hydroxyanthranilic.acid 1 13.143 530.75 272.08
## - p.Cresol.sulfate 1 13.730 531.34 272.40
## - X5.Aminopentanoic.acid 1 15.858 533.47 273.57
## - S.ganine.1.phosphate_b 1 16.208 533.82 273.77
## - Ascorbic.acid 1 17.159 534.77 274.29
## - Phenyl.sulfate 1 17.251 534.86 274.34
## - Indole.3.carboxaldehyde 1 17.421 535.03 274.43
## - Pantothenol 1 17.514 535.12 274.48
## - AST..U.L. 1 22.882 540.49 277.41
## - X3.Hydroxypropionic.acid 1 23.494 541.10 277.74
## - Kynurenic.acid 1 24.901 542.51 278.50
## - X3..3.Hydroxyphenyl..3.hydroxypropanoic.acid 1 25.067 542.68 278.59
## - Acetylglycine 1 26.226 543.84 279.21
## - Sphinganine 1 30.602 548.21 281.56
## - Indole.3.methyl.acetate 1 30.919 548.53 281.73
## - X1.5.Anhydrosorbitol 1 34.211 551.82 283.48
## - HDL.C..mM. 1 36.075 553.69 284.47
## - ALT..U.L. 1 39.402 557.01 286.23
## - Indole.3.acrylic.acid 1 52.984 570.59 293.29
## - X3.Indolebutyric.acid 1 59.605 577.22 296.67
## - Palmitoylethanolamide 1 61.870 579.48 297.81
## - TG..mM. 1 85.925 603.54 309.73
##
## Step: AIC=266.29
## FBG..mM. ~ ALT..U.L. + AST..U.L. + ALB..g.L. + TG..mM. + HDL.C..mM. +
## T.BIL..uM. + D.BIL..uM. + NEUT.... + LYMPH.... + EO.... +
## Phenylethylamine + Octadecanamide + Imidazolepropionic.acid +
## Indole.3.carboxaldehyde + X3.Hydroxyanthranilic.acid + Oleamide +
## Palmitoylethanolamide + Bilirubin...47 + Indole.3.acrylic.acid +
## Kynurenic.acid + Indole.3.methyl.acetate + Sphinganine +
## Sphinganine.1.phosphate + X3.Indolebutyric.acid + Phenylacetylglutamine.PAGln. +
## Pantothenol + Gamma.aminobutyric.acid + X5.Aminopentanoic.acid +
## N.Acetylcadaverine + N8.Acetylspermidine + X1.5.Anhydrosorbitol +
## Salicylic.acid + Phenyllactate + Bilirubin...82 + X3..3.Hydroxyphenyl..3.hydroxypropanoic.acid +
## p.Cresol.sulfate + X2.Hydroxy.Hippuric.Acid + X3.Hydroxyhippuric.acid +
## S.ganine.1.phosphate_b + Cholesterol.sulfate + Xanthurenic.acid +
## Cinnamoylglycine + Indoxyl.sulfate + Ascorbic.acid + Homovanillic.acid.sulfate +
## Phenyl.sulfate + X3.Hydroxypropionic.acid + Acetylglycine
##
## Df Sum of Sq RSS AIC
## - EO.... 1 3.165 523.54 266.07
## <none> 520.37 266.29
## - Bilirubin...47 1 4.057 524.43 266.57
## - Cinnamoylglycine 1 4.353 524.73 266.73
## + Phenol 1 2.762 517.61 266.73
## + N.acetyl.aspartic.acid 1 2.669 517.70 266.78
## + Urocanic.acid 1 2.450 517.92 266.91
## - Imidazolepropionic.acid 1 5.111 525.48 267.15
## + ALP..U.L. 1 1.629 518.74 267.37
## + Spermine 1 1.506 518.87 267.44
## - N8.Acetylspermidine 1 5.779 526.15 267.53
## + Hippuric.acid 1 1.279 519.09 267.57
## - X2.Hydroxy.Hippuric.Acid 1 5.881 526.25 267.58
## - Cholesterol.sulfate 1 5.900 526.27 267.59
## + Iodide 1 1.181 519.19 267.62
## + TBA..uM. 1 0.965 519.41 267.75
## + X3.Hydroxyphenylacetic.acid 1 0.951 519.42 267.75
## + X3.Hydroxybenzoic.acid 1 0.947 519.42 267.76
## - Sphinganine.1.phosphate 1 6.301 526.67 267.82
## + Acetylcholine 1 0.840 519.53 267.82
## + Spermidine 1 0.689 519.68 267.90
## + X4.Hydroxyphenyllactate 1 0.651 519.72 267.92
## + p.Cresol 1 0.576 519.80 267.97
## + X5.Methoxyindoleacetate 1 0.510 519.86 268.00
## + X4.Hydroxybenzoic.acid.4.O.sulphate 1 0.432 519.94 268.05
## + X4.Hydroxybenzoic.acid 1 0.427 519.95 268.05
## + Biliverdin 1 0.419 519.95 268.06
## + Indole.3.propionic.acid 1 0.385 519.99 268.07
## - Homovanillic.acid.sulfate 1 6.789 527.16 268.09
## + Cre..uM. 1 0.337 520.04 268.10
## + LDL.C..mM. 1 0.271 520.10 268.14
## - ALB..g.L. 1 6.884 527.26 268.14
## + X4.Hydroxyphenylpropionate 1 0.265 520.11 268.14
## + Dopamine 1 0.223 520.15 268.17
## + Dopa 1 0.190 520.18 268.18
## + BASO.... 1 0.163 520.21 268.20
## + Oleoylethanolamide 1 0.150 520.22 268.21
## + TC..mM. 1 0.146 520.23 268.21
## + CHE..U.L. 1 0.143 520.23 268.21
## + Benzoic.acid 1 0.102 520.27 268.23
## + Enterolactone 1 0.102 520.27 268.23
## + p.Cresol.glucuronide 1 0.079 520.29 268.25
## + Stearoylethanolamide 1 0.075 520.30 268.25
## + Sphingosine 1 0.074 520.30 268.25
## + Palmitic.amide 1 0.045 520.33 268.26
## + Υ.GT..U.L. 1 0.020 520.35 268.28
## + UA..uM. 1 0.015 520.36 268.28
## + WBC..10.9.L. 1 0.010 520.36 268.29
## + Sphingosine.1.phosphate 1 0.008 520.36 268.29
## + Putrescine 1 0.006 520.37 268.29
## + S.gosine.1.phosphate_b 1 0.005 520.37 268.29
## + Urea..mM. 1 0.003 520.37 268.29
## + X4.Ethylphenyl.sulfate 1 0.000 520.37 268.29
## + Phenylacetic.acid 1 0.000 520.37 268.29
## - Phenyllactate 1 7.673 528.05 268.58
## - NEUT.... 1 7.810 528.18 268.66
## - Phenylethylamine 1 8.117 528.49 268.83
## - Bilirubin...82 1 8.175 528.55 268.86
## - LYMPH.... 1 8.328 528.70 268.94
## - Salicylic.acid 1 8.685 529.06 269.14
## - Oleamide 1 8.762 529.13 269.18
## - Xanthurenic.acid 1 8.820 529.19 269.21
## - Octadecanamide 1 8.952 529.32 269.29
## - X3.Hydroxyhippuric.acid 1 9.078 529.45 269.36
## - N.Acetylcadaverine 1 9.134 529.51 269.39
## - Indoxyl.sulfate 1 9.361 529.73 269.51
## - Phenylacetylglutamine.PAGln. 1 9.621 529.99 269.66
## - D.BIL..uM. 1 9.889 530.26 269.81
## - Gamma.aminobutyric.acid 1 10.785 531.16 270.30
## - T.BIL..uM. 1 11.031 531.40 270.44
## - X3.Hydroxyanthranilic.acid 1 13.049 533.42 271.55
## - Phenyl.sulfate 1 14.696 535.07 272.45
## - X5.Aminopentanoic.acid 1 14.810 535.18 272.51
## - Indole.3.carboxaldehyde 1 16.146 536.52 273.24
## - Ascorbic.acid 1 16.523 536.90 273.45
## - p.Cresol.sulfate 1 16.833 537.21 273.62
## - S.ganine.1.phosphate_b 1 17.622 537.99 274.05
## - Pantothenol 1 18.751 539.12 274.66
## - AST..U.L. 1 21.580 541.95 276.20
## - X3.Hydroxypropionic.acid 1 23.109 543.48 277.02
## - X3..3.Hydroxyphenyl..3.hydroxypropanoic.acid 1 25.164 545.54 278.13
## - Acetylglycine 1 25.799 546.17 278.47
## - Kynurenic.acid 1 26.086 546.46 278.62
## - Indole.3.methyl.acetate 1 31.643 552.01 281.59
## - Sphinganine 1 31.992 552.36 281.77
## - X1.5.Anhydrosorbitol 1 35.223 555.60 283.48
## - HDL.C..mM. 1 36.312 556.68 284.06
## - ALT..U.L. 1 37.932 558.30 284.91
## - Indole.3.acrylic.acid 1 52.844 573.22 292.63
## - X3.Indolebutyric.acid 1 57.640 578.01 295.07
## - Palmitoylethanolamide 1 60.910 581.28 296.72
## - TG..mM. 1 86.603 606.98 309.40
##
## Step: AIC=266.07
## FBG..mM. ~ ALT..U.L. + AST..U.L. + ALB..g.L. + TG..mM. + HDL.C..mM. +
## T.BIL..uM. + D.BIL..uM. + NEUT.... + LYMPH.... + Phenylethylamine +
## Octadecanamide + Imidazolepropionic.acid + Indole.3.carboxaldehyde +
## X3.Hydroxyanthranilic.acid + Oleamide + Palmitoylethanolamide +
## Bilirubin...47 + Indole.3.acrylic.acid + Kynurenic.acid +
## Indole.3.methyl.acetate + Sphinganine + Sphinganine.1.phosphate +
## X3.Indolebutyric.acid + Phenylacetylglutamine.PAGln. + Pantothenol +
## Gamma.aminobutyric.acid + X5.Aminopentanoic.acid + N.Acetylcadaverine +
## N8.Acetylspermidine + X1.5.Anhydrosorbitol + Salicylic.acid +
## Phenyllactate + Bilirubin...82 + X3..3.Hydroxyphenyl..3.hydroxypropanoic.acid +
## p.Cresol.sulfate + X2.Hydroxy.Hippuric.Acid + X3.Hydroxyhippuric.acid +
## S.ganine.1.phosphate_b + Cholesterol.sulfate + Xanthurenic.acid +
## Cinnamoylglycine + Indoxyl.sulfate + Ascorbic.acid + Homovanillic.acid.sulfate +
## Phenyl.sulfate + X3.Hydroxypropionic.acid + Acetylglycine
##
## Df Sum of Sq RSS AIC
## <none> 523.54 266.07
## - Cinnamoylglycine 1 3.944 527.48 266.27
## + EO.... 1 3.165 520.37 266.29
## + Urocanic.acid 1 2.953 520.58 266.41
## + N.acetyl.aspartic.acid 1 2.810 520.73 266.49
## + Phenol 1 2.381 521.16 266.73
## - Bilirubin...47 1 4.944 528.48 266.82
## - NEUT.... 1 5.081 528.62 266.90
## - LYMPH.... 1 5.441 528.98 267.10
## + ALP..U.L. 1 1.628 521.91 267.15
## - N8.Acetylspermidine 1 5.572 529.11 267.17
## - X2.Hydroxy.Hippuric.Acid 1 5.590 529.13 267.18
## - Imidazolepropionic.acid 1 5.650 529.19 267.21
## + Spermine 1 1.454 522.08 267.25
## + X3.Hydroxyphenylacetic.acid 1 1.381 522.16 267.29
## + Iodide 1 1.300 522.24 267.34
## - Cholesterol.sulfate 1 5.920 529.46 267.36
## + X3.Hydroxybenzoic.acid 1 1.117 522.42 267.44
## + Hippuric.acid 1 0.992 522.55 267.51
## - Sphinganine.1.phosphate 1 6.205 529.74 267.52
## + X4.Hydroxyphenyllactate 1 0.924 522.61 267.55
## - Homovanillic.acid.sulfate 1 6.345 529.88 267.60
## + Spermidine 1 0.783 522.75 267.63
## + Acetylcholine 1 0.673 522.86 267.69
## + p.Cresol 1 0.641 522.90 267.71
## + TBA..uM. 1 0.592 522.95 267.74
## + X5.Methoxyindoleacetate 1 0.375 523.16 267.86
## + Dopamine 1 0.354 523.18 267.87
## + LDL.C..mM. 1 0.351 523.19 267.87
## + X4.Hydroxybenzoic.acid.4.O.sulphate 1 0.339 523.20 267.88
## + X4.Hydroxyphenylpropionate 1 0.302 523.24 267.90
## + Cre..uM. 1 0.275 523.26 267.91
## + Indole.3.propionic.acid 1 0.266 523.27 267.92
## - ALB..g.L. 1 6.931 530.47 267.92
## + Biliverdin 1 0.226 523.31 267.94
## + CHE..U.L. 1 0.204 523.33 267.95
## + Benzoic.acid 1 0.192 523.35 267.96
## + Sphingosine 1 0.186 523.35 267.96
## + p.Cresol.glucuronide 1 0.120 523.42 268.00
## - Phenylethylamine 1 7.084 530.62 268.01
## + Dopa 1 0.109 523.43 268.01
## + TC..mM. 1 0.098 523.44 268.01
## + Enterolactone 1 0.087 523.45 268.02
## + WBC..10.9.L. 1 0.071 523.47 268.03
## + Sphingosine.1.phosphate 1 0.053 523.48 268.04
## + X4.Hydroxybenzoic.acid 1 0.051 523.49 268.04
## + Oleoylethanolamide 1 0.049 523.49 268.04
## + Phenylacetic.acid 1 0.042 523.50 268.04
## + Palmitic.amide 1 0.040 523.50 268.05
## + Putrescine 1 0.027 523.51 268.05
## + Stearoylethanolamide 1 0.024 523.51 268.05
## + Υ.GT..U.L. 1 0.016 523.52 268.06
## + BASO.... 1 0.007 523.53 268.06
## + Urea..mM. 1 0.005 523.53 268.06
## + X4.Ethylphenyl.sulfate 1 0.002 523.54 268.07
## + UA..uM. 1 0.001 523.54 268.07
## + S.gosine.1.phosphate_b 1 0.000 523.54 268.07
## - Phenyllactate 1 7.639 531.18 268.31
## - Oleamide 1 7.796 531.33 268.40
## - Salicylic.acid 1 8.351 531.89 268.70
## - Octadecanamide 1 8.664 532.20 268.88
## - Xanthurenic.acid 1 8.721 532.26 268.91
## - Bilirubin...82 1 9.743 533.28 269.47
## - N.Acetylcadaverine 1 9.753 533.29 269.48
## - X3.Hydroxyhippuric.acid 1 9.924 533.46 269.57
## - Phenylacetylglutamine.PAGln. 1 10.186 533.72 269.71
## - Indoxyl.sulfate 1 10.380 533.92 269.82
## - Gamma.aminobutyric.acid 1 10.886 534.42 270.10
## - D.BIL..uM. 1 11.261 534.80 270.30
## - T.BIL..uM. 1 12.791 536.33 271.14
## - X3.Hydroxyanthranilic.acid 1 12.807 536.34 271.15
## - Phenyl.sulfate 1 13.206 536.74 271.37
## - X5.Aminopentanoic.acid 1 15.070 538.61 272.38
## - Indole.3.carboxaldehyde 1 15.173 538.71 272.44
## - p.Cresol.sulfate 1 16.917 540.45 273.39
## - Ascorbic.acid 1 16.959 540.50 273.41
## - Pantothenol 1 17.921 541.46 273.93
## - S.ganine.1.phosphate_b 1 18.283 541.82 274.12
## - AST..U.L. 1 20.622 544.16 275.39
## - X3.Hydroxypropionic.acid 1 23.211 546.75 276.78
## - X3..3.Hydroxyphenyl..3.hydroxypropanoic.acid 1 25.864 549.40 278.20
## - Acetylglycine 1 27.548 551.09 279.09
## - Kynurenic.acid 1 28.723 552.26 279.72
## - Sphinganine 1 32.098 555.63 281.50
## - Indole.3.methyl.acetate 1 32.618 556.16 281.78
## - X1.5.Anhydrosorbitol 1 34.945 558.48 283.00
## - ALT..U.L. 1 37.874 561.41 284.53
## - HDL.C..mM. 1 38.095 561.63 284.65
## - Indole.3.acrylic.acid 1 54.346 577.88 293.00
## - Palmitoylethanolamide 1 59.587 583.12 295.65
## - X3.Indolebutyric.acid 1 60.700 584.24 296.21
## - TG..mM. 1 86.843 610.38 309.04
#summary
#summary(modelo_backward)
#Ver proceso
#modelo_backward$anova
#Para mostrar las var seleccionada
names(modelo_both$coefficients)
## [1] "(Intercept)"
## [2] "ALT..U.L."
## [3] "AST..U.L."
## [4] "ALB..g.L."
## [5] "TG..mM."
## [6] "HDL.C..mM."
## [7] "T.BIL..uM."
## [8] "D.BIL..uM."
## [9] "NEUT...."
## [10] "LYMPH...."
## [11] "Phenylethylamine"
## [12] "Octadecanamide"
## [13] "Imidazolepropionic.acid"
## [14] "Indole.3.carboxaldehyde"
## [15] "X3.Hydroxyanthranilic.acid"
## [16] "Oleamide"
## [17] "Palmitoylethanolamide"
## [18] "Bilirubin...47"
## [19] "Indole.3.acrylic.acid"
## [20] "Kynurenic.acid"
## [21] "Indole.3.methyl.acetate"
## [22] "Sphinganine"
## [23] "Sphinganine.1.phosphate"
## [24] "X3.Indolebutyric.acid"
## [25] "Phenylacetylglutamine.PAGln."
## [26] "Pantothenol"
## [27] "Gamma.aminobutyric.acid"
## [28] "X5.Aminopentanoic.acid"
## [29] "N.Acetylcadaverine"
## [30] "N8.Acetylspermidine"
## [31] "X1.5.Anhydrosorbitol"
## [32] "Salicylic.acid"
## [33] "Phenyllactate"
## [34] "Bilirubin...82"
## [35] "X3..3.Hydroxyphenyl..3.hydroxypropanoic.acid"
## [36] "p.Cresol.sulfate"
## [37] "X2.Hydroxy.Hippuric.Acid"
## [38] "X3.Hydroxyhippuric.acid"
## [39] "S.ganine.1.phosphate_b"
## [40] "Cholesterol.sulfate"
## [41] "Xanthurenic.acid"
## [42] "Cinnamoylglycine"
## [43] "Indoxyl.sulfate"
## [44] "Ascorbic.acid"
## [45] "Homovanillic.acid.sulfate"
## [46] "Phenyl.sulfate"
## [47] "X3.Hydroxypropionic.acid"
## [48] "Acetylglycine"
Bboth <- Basecom %>% select(14, 15, 19, 21, 22, 26, 27, 32, 35, 36)
# vector de medias
center <- colMeans(Bboth)
# matriz de covarianza
cov_matrix <- cov(Bboth)
#distancia de mahalanobis
dist_mahal_Bboth <- mahalanobis(Bboth, center, cov_matrix)
# Distancias
boxplot(dist_mahal_Bboth,
main = "Distancia de Mahalanobis",
ylab = "D² (desviaciones multivariadas)",
col = "lightblue")
#95IC
umbral <- qchisq(0.95, df = ncol(Bboth))
#outliers
outliers <- which(dist_mahal_Bboth > umbral)
outliers
## [1] 9 24 26 27 30 32 44 55 57 58 66 67 68 84 86 87 91 94 131
## [20] 139 146 147 163 168 170 196 199 220 232 253 255
#Gráfico
plot(dist_mahal_Bboth, pch = 19, col = "steelblue",
main = "Distancia de Mahalanobis por observación",
ylab = "D²", xlab = "Observación")
abline(h = umbral, col = "red", lwd = 2, lty = 2)
#Etiquetas para los outliers
text(outliers, dist_mahal_Bboth[outliers], labels = outliers, pos = 3, col = "red")
Distancias de mahalanobis - 20 biomarcadores con mayor varianza
# Varianza de cada columna
varianzas <- sapply(M4, function(x) {
if (is.numeric(x)) var(x, na.rm = TRUE) else NA
})
# Convertir a df
varianzas_df <- data.frame(
Variable = names(varianzas),
Varianza = varianzas
) %>%
arrange(desc(Varianza)) %>%
na.omit()
# Mostrar las primeras 20
head(varianzas_df, 21)
M41 <- Basecom %>%
select("Putrescine", "Bilirubin...82", "Gamma-aminobutyric acid",
"4-Ethylphenyl sulfate", "Phenol", "Ascorbic acid", "p-Cresol",
"3-Hydroxyphenylacetic acid", "1,5-Anhydrosorbitol", "Phenyl sulfate",
"5-Aminopentanoic acid", "Indole-3-propionic acid", "p-Cresol sulfate",
"Cholesterol sulfate", "Oleamide", "Hippuric acid", "Indoxyl sulfate",
"3-Hydroxypropionic acid", "4-Hydroxybenzoic acid", "Salicylic acid")
# vector de medias
center <- colMeans(M41)
# matriz de covarianza
cov_matrix <- cov(M41)
#distancia de mahalanobis
dist_mahal_20mvar <- mahalanobis(M41, center, cov_matrix)
# Distancias
boxplot(dist_mahal_20mvar,
main = "Distancia de Mahalanobis",
ylab = "D² (desviaciones multivariadas)",
col = "lightblue")
#95IC
umbral <- qchisq(0.95, df = ncol(M41))
#outliers
outliers <- which(dist_mahal_20mvar > umbral)
outliers
## [1] 2 5 7 15 17 18 20 43 44 48 49 52 61 66 76 80 86 97 101
## [20] 114 116 118 128 130 131 175 217 239 248 249 250 255 257 276 279
#Gráfico
plot(dist_mahal_20mvar, pch = 19, col = "steelblue",
main = "Distancia de Mahalanobis por observación",
ylab = "D²", xlab = "Observación")
abline(h = umbral, col = "red", lwd = 2, lty = 2)
#Etiquetas para los outliers
text(outliers, dist_mahal_20mvar[outliers], labels = outliers, pos = 3, col = "red")
DM escalada por sd
# DM estandarizada usando la desviación estándar
dist_mahal_sd <- dist_mahal_20mvar / sd(dist_mahal_20mvar)
#Distancias
boxplot(dist_mahal_sd,
main = "Distancia de Mahalanobis estandarizada",
ylab = "DM / SD(DM)",
col = "lightblue")
#95IC
umbral <- qchisq(0.95, df = ncol(M41))
#outliers
outliers <- which(dist_mahal_20mvar > umbral)
outliers
## [1] 2 5 7 15 17 18 20 43 44 48 49 52 61 66 76 80 86 97 101
## [20] 114 116 118 128 130 131 175 217 239 248 249 250 255 257 276 279
#Gráfico
plot(dist_mahal_sd,pch = 19, col = "steelblue",
main = "Distancia de Mahalanobis estandarizada por sd",
ylab = "DM / SD(DM)", xlab = "Observación")
abline(h = umbral, col = "red", lwd = 2, lty = 2)
#El umbral no sale en la gráfica pq tiene un valor de 50
#Etiquetas para los outliers
text(outliers, dist_mahal_20mvar[outliers], labels = outliers, pos = 3, col = "red")
Log base 10 de la DM
# Log base 10 de la DM
dist_mahal_log10 <- log10(dist_mahal_20mvar)
boxplot(dist_mahal_log10,
main = "Log10 de la Distancia de Mahalanobis",
ylab = "log10(D²)",
col = "lightblue")
plot(dist_mahal_log10,
pch = 19,
col = "steelblue",
main = "Log10 de la Distancia de Mahalanobis",
ylab = "log10(D²)",
xlab = "Observación")
Log n de la DM
# Log natural de la DM
dist_mahal_log <- log(dist_mahal_20mvar)
boxplot(dist_mahal_log,
main = "Log natural de la Distancia de Mahalanobis",
ylab = "log n(D²)",
col = "lightblue")
plot(dist_mahal_log,
pch = 19,
col = "steelblue",
main = "Log natural de la Distancia de Mahalanobis",
ylab = "log n(D²)",
xlab = "Observación")
Distancias de Mahalanobis - 20 biomarcadores con menor
correlación
# Menor correlación
# matriz correlación
corr_matrix <- cor(M4, use = "pairwise.complete.obs")
#promedio de correlación
prom_corr <- apply(abs(corr_matrix), 2, mean, na.rm = TRUE)
# ordenar
prom_corr_sorted <- sort(prom_corr)
#mostrar las primeras
top20_independientes <- head(prom_corr_sorted, 20)
top20_independientes
## Enterolactone
## 0.04916222
## Phenyl sulfate
## 0.05372274
## Spermine
## 0.07232962
## Urocanic acid
## 0.07260347
## 3-Hydroxybenzoic acid
## 0.07511203
## 3-(3-Hydroxyphenyl)-3-hydroxypropanoic acid
## 0.07633252
## Oleamide
## 0.07898457
## Benzoic acid
## 0.07915423
## 4-Ethylphenyl sulfate
## 0.08005445
## Iodide
## 0.08147291
## 3-Hydroxyphenylacetic acid
## 0.08201009
## N8-Acetylspermidine
## 0.08285117
## Homovanillic acid sulfate
## 0.08321448
## 3-Indolebutyric acid
## 0.08636390
## Palmitic amide
## 0.08667606
## 2-Hydroxy Hippuric Acid
## 0.08732845
## Hippuric acid
## 0.08864545
## Phenylethylamine
## 0.08938010
## Phenol
## 0.08961371
## Salicylic acid
## 0.08963614
# Menor correlación
M41 <- Basecom %>%
select("Enterolactone", "Phenyl sulfate", "Spermine", "Urocanic acid",
"3-Hydroxybenzoic acid", "3-(3-Hydroxyphenyl)-3-hydroxypropanoic acid",
"Oleamide", "Benzoic acid", "4-Ethylphenyl sulfate", "Iodide",
"3-Hydroxyphenylacetic acid", "N8-Acetylspermidine", "Homovanillic acid sulfate",
"3-Indolebutyric acid", "Palmitic amide", "2-Hydroxy Hippuric Acid",
"Hippuric acid", "Phenylethylamine", "Phenol", "Salicylic acid")
# vector de medias
center <- colMeans(M41)
# matriz de covarianza
cov_matrix <- cov(M41)
#distancia de mahalanobis
dist_mahal_20menor_cor <- mahalanobis(M41, center, cov_matrix)
# Distancias
boxplot(dist_mahal_20menor_cor,
main = "Distancia de Mahalanobis",
ylab = "D² (desviaciones multivariadas)",
col = "lightblue")
#95IC
umbral <- qchisq(0.95, df = ncol(M41))
#outliers
outliers <- which(dist_mahal_20menor_cor > umbral)
outliers
## [1] 2 7 8 9 17 19 23 30 41 43 44 48 51 53 61 64 66 75 81
## [20] 86 106 114 116 137 145 155 161 162 164 167 189 199 216 217 221 239 248 249
## [39] 253 257
#Gráfico
plot(dist_mahal_20menor_cor, pch = 19, col = "steelblue",
main = "Distancia de Mahalanobis, sexto grupo (20 con menor correlación)",
ylab = "D²", xlab = "Observación")
abline(h = umbral, col = "red", lwd = 2, lty = 2)
#Etiquetas para los outliers
text(outliers, dist_mahal_20menor_cor[outliers], labels = outliers, pos = 3, col = "red")
Distancias de Mahalanobis - 20 con menor correlación y mayor
varianza
# matriz cor
corr_matrix <- cor(M4, use = "pairwise.complete.obs")
# valor abs de cada cor
prom_corr <- apply(abs(corr_matrix), 1, mean, na.rm = TRUE)
# varianza de cada variable
varianzas <- sapply(M4, function(x) var(as.numeric(x), na.rm = TRUE))
# combinar en un df
summary_df <- data.frame(
Variable = names(prom_corr),
Prom_Corr = prom_corr,
Varianza = varianzas
)
# ordenar con menor correlación promedio y mayor varianza
summary_df <- summary_df[order(summary_df$Prom_Corr, -summary_df$Varianza), ]
#primerqas 20
head(summary_df, 40)
# Menor correlación y mayor varianza
M41 <- Basecom %>%
select("Phenyl sulfate", "Spermine", "Urocanic acid",
"3-(3-Hydroxyphenyl)-3-hydroxypropanoic acid",
"Oleamide", "Benzoic acid", "4-Ethylphenyl sulfate", "Iodide",
"3-Hydroxyphenylacetic acid", "N8-Acetylspermidine", "Homovanillic acid sulfate",
"Palmitic amide", "2-Hydroxy Hippuric Acid",
"Hippuric acid", "Phenol", "Salicylic acid", "Dopamine", "3-Hydroxyhippuric acid",
"4-Hydroxybenzoic acid", "Gamma-aminobutyric acid")
# vector de medias
center <- colMeans(M41)
# matriz de covarianza
cov_matrix <- cov(M41)
#distancia de mahalanobis
dist_mahal_20menorcor_mayorvar <- mahalanobis(M41, center, cov_matrix)
# Distancias
boxplot(dist_mahal_20menorcor_mayorvar,
main = "Distancia de Mahalanobis",
ylab = "D² (desviaciones multivariadas)",
col = "lightblue")
#95IC
umbral <- qchisq(0.95, df = ncol(M41))
#outliers
outliers <- which(dist_mahal_20menorcor_mayorvar > umbral)
outliers
## [1] 2 7 8 17 23 30 41 43 44 48 49 51 53 61 64 66 81 86 102
## [20] 106 114 116 137 155 161 162 191 216 217 239 248 249 253 257 272
#Gráfico
plot(dist_mahal_20menorcor_mayorvar, pch = 19, col = "steelblue",
main = "DM, séptimo grupo (20 con menor correlación y mayor varianza)",
ylab = "D²", xlab = "Observación")
abline(h = umbral, col = "red", lwd = 2, lty = 2)
#Etiquetas para los outliers
text(outliers, dist_mahal_20menorcor_mayorvar[outliers], labels = outliers, pos = 3, col = "red")
Tabla 2
# Convertir variable dependiente en binaria
Basecom <- Basecom %>%
mutate(Group_bin = ifelse(Group == 1, 1, 0))
# Lista de distancias
dist_vars <- list(
DM_Bline = dist_mahal_bline,
DM_M4 = dist_mahal_M4,
DM_Bcom = dist_mahal_Bcom,
DM_Bboth = dist_mahal_Bboth,
DM_20mvar = dist_mahal_20mvar,
DM_SD = dist_mahal_sd,
DM_log10 = dist_mahal_log10,
DM_ln = dist_mahal_log,
DM_20menor_cor = dist_mahal_20menor_cor,
DM_20menorcor_mayorvar = dist_mahal_20menorcor_mayorvar
)
# Guardar resultados
resultados <- list()
#
for (nombre in names(dist_vars)) {
# Extraer vector
dist <- as.numeric(dist_vars[[nombre]])
# Dataframe temporal
datos_modelo <- data.frame(
Group_bin = Basecom$Group_bin,
dist = dist
)
# Modelo
modelo <- glm(Group_bin ~ dist,
data = datos_modelo,
family = binomial())
# Resumen
beta <- coef(modelo)[2]
OR <- exp(beta)
# IC 95%
conf <- exp(confint.default(modelo))
# AIC y BIC
AIC_val <- AIC(modelo)
BIC_val <- BIC(modelo)
# Tabla parcial
resultado <- tibble(
Predictor = nombre,
Beta = round(beta, 4),
OR = round(OR, 4),
`IC 95% Inferior` = round(conf[2, 1], 4),
`IC 95% Superior` = round(conf[2, 2], 4),
`Valor p` = as.character(
ifelse(coef(summary(modelo))[2, 4] < 0.0001,
"<0.0001",
round(coef(summary(modelo))[2, 4], 4))
),
AIC = round(AIC_val, 2),
BIC = round(BIC_val, 2)
)
resultados[[nombre]] <- resultado
}
# Unir resultados
tabla_mahalanobis <- bind_rows(resultados)
# Mostrar tabla
tabla_mahalanobis %>%
kable(
format = "html",
caption = "Tabla 2: Relación entre las distancias de Mahalanobis y diabetes"
) %>%
kable_styling(
bootstrap_options = c("striped", "hover", "condensed"),
full_width = FALSE,
position = "center"
)
Tabla 2: Relación entre las distancias de Mahalanobis y diabetes
|
Predictor
|
Beta
|
OR
|
IC 95% Inferior
|
IC 95% Superior
|
Valor p
|
AIC
|
BIC
|
|
DM_Bline
|
0.0143
|
1.0144
|
1.0005
|
1.0285
|
0.0419
|
370.78
|
378.14
|
|
DM_M4
|
0.0079
|
1.0079
|
1.0018
|
1.0140
|
0.0113
|
369.38
|
376.74
|
|
DM_Bcom
|
0.0102
|
1.0102
|
1.0041
|
1.0163
|
0.001
|
364.45
|
371.81
|
|
DM_Bboth
|
0.0361
|
1.0368
|
1.0126
|
1.0615
|
0.0027
|
363.19
|
370.55
|
|
DM_20mvar
|
0.0110
|
1.0111
|
1.0009
|
1.0214
|
0.0335
|
370.59
|
377.96
|
|
DM_SD
|
0.2971
|
1.3459
|
1.0234
|
1.7700
|
0.0335
|
370.59
|
377.96
|
|
DM_log10
|
1.2040
|
3.3333
|
1.5779
|
7.0416
|
0.0016
|
365.73
|
373.09
|
|
DM_ln
|
0.5229
|
1.6869
|
1.2190
|
2.3342
|
0.0016
|
365.73
|
373.09
|
|
DM_20menor_cor
|
0.0066
|
1.0066
|
0.9994
|
1.0138
|
0.0718
|
372.69
|
380.05
|
|
DM_20menorcor_mayorvar
|
0.0098
|
1.0099
|
1.0020
|
1.0178
|
0.014
|
368.80
|
376.16
|
Tabla 2 ajustada por edad y sexo