Characteristic African
N = 160
1
Asian
N = 36
1
European
N = 192
1
Other/Admixed
N = 6
1
p-value2
Sex



0.6
    Male 85/160 (53%) 23/36 (64%) 110/192 (57%) 4/6 (67%)
    Female 75/160 (47%) 13/36 (36%) 82/192 (43%) 2/6 (33%)
Age at diagnosis, years 59 (51-66) 62 (51-67) 66 (57-73) 58 (50-64) <0.001
Prior MGUS



0.2
    Yes 48/142 (34%) 8/32 (25%) 72/170 (42%) 2/5 (40%)
    No 94/142 (66%) 24/32 (75%) 98/170 (58%) 3/5 (60%)
Diagnosis



0.14
    Amyloidosis 18/159 (11%) 8/36 (22%) 12/192 (6.3%) 0/6 (0%)
    MGUS 14/159 (8.8%) 4/36 (11%) 21/192 (11%) 1/6 (17%)
    MM 116/159 (73%) 22/36 (61%) 137/192 (71%) 4/6 (67%)
    Other 0/159 (0%) 0/36 (0%) 2/192 (1.0%) 0/6 (0%)
    POEMS 4/159 (2.5%) 1/36 (2.8%) 1/192 (0.5%) 0/6 (0%)
    SMM 7/159 (4.4%) 1/36 (2.8%) 19/192 (9.9%) 1/6 (17%)
Bone marrow plasma cells, % 25 (10-60) 20 (10-45) 30 (10-50) 20 (20-80) 0.7
ISS stage at diagnosis



0.6
    I 88/141 (62%) 19/32 (59%) 96/147 (65%) 2/5 (40%)
    II 32/141 (23%) 6/32 (19%) 35/147 (24%) 2/5 (40%)
    III 21/141 (15%) 7/32 (22%) 16/147 (11%) 1/5 (20%)
R-ISS stage



0.084
    I 121/153 (79%) 26/33 (79%) 155/186 (83%) 3/6 (50%)
    II 9/153 (5.9%) 2/33 (6.1%) 7/186 (3.8%) 2/6 (33%)
    III 23/153 (15%) 5/33 (15%) 24/186 (13%) 1/6 (17%)
1 n/N (%); Median (Q1-Q3)
2 Pearson’s Chi-squared test; Kruskal-Wallis rank sum test