Characteristic Community
N = 81		 Farm
N = 5851		 Hospital
N = 651		 Market
N = 5041		 p-value2
gene



<0.001
    aadA1 1 (13%) 0 (0%) 1 (1.5%) 9 (1.8%)
    aadA2 1 (13%) 29 (5.0%) 2 (3.1%) 48 (9.5%)
    arsA 0 (0%) 40 (6.8%) 1 (1.5%) 33 (6.5%)
    arsB 0 (0%) 14 (2.4%) 4 (6.2%) 21 (4.2%)
    arsC 0 (0%) 24 (4.1%) 6 (9.2%) 46 (9.1%)
    arsD 0 (0%) 74 (13%) 1 (1.5%) 35 (6.9%)
    arsH 0 (0%) 37 (6.3%) 0 (0%) 15 (3.0%)
    arsR 0 (0%) 53 (9.1%) 6 (9.2%) 42 (8.3%)
    blaCTX-M-15 0 (0%) 25 (4.3%) 6 (9.2%) 6 (1.2%)
    blaCTX-M-55 1 (13%) 2 (0.3%) 3 (4.6%) 5 (1.0%)
    blaDHA 0 (0%) 0 (0%) 0 (0%) 1 (0.2%)
    blaOXA-1 0 (0%) 11 (1.9%) 0 (0%) 2 (0.4%)
    blaSHV-12 0 (0%) 10 (1.7%) 0 (0%) 20 (4.0%)
    copB 0 (0%) 17 (2.9%) 5 (7.7%) 21 (4.2%)
    copG 0 (0%) 2 (0.3%) 3 (4.6%) 27 (5.4%)
    czcO 1 (13%) 4 (0.7%) 1 (1.5%) 12 (2.4%)
    merA 0 (0%) 22 (3.8%) 3 (4.6%) 8 (1.6%)
    merR 0 (0%) 15 (2.6%) 4 (6.2%) 9 (1.8%)
    merT 0 (0%) 16 (2.7%) 4 (6.2%) 8 (1.6%)
    qacE 0 (0%) 2 (0.3%) 2 (3.1%) 2 (0.4%)
    qacEdelta1 2 (25%) 49 (8.4%) 1 (1.5%) 34 (6.7%)
    qacL 0 (0%) 1 (0.2%) 1 (1.5%) 6 (1.2%)
    silE 0 (0%) 65 (11%) 5 (7.7%) 37 (7.3%)
    silP 0 (0%) 19 (3.2%) 3 (4.6%) 21 (4.2%)
    sul1 2 (25%) 54 (9.2%) 3 (4.6%) 36 (7.1%)
associated_IS_families



<0.001
    IS1 0 (0%) 26 (4.4%) 3 (4.6%) 26 (5.2%)
    IS1 + IS256 + IS6 0 (0%) 0 (0%) 0 (0%) 1 (0.2%)
    IS1 + IS256 + IS6 + IS91 0 (0%) 0 (0%) 0 (0%) 1 (0.2%)
    IS1 + IS3 0 (0%) 16 (2.7%) 0 (0%) 6 (1.2%)
    IS1 + IS3 + IS5 0 (0%) 1 (0.2%) 0 (0%) 0 (0%)
    IS1 + IS3 + IS5 + IS6 0 (0%) 3 (0.5%) 1 (1.5%) 0 (0%)
    IS1 + IS4 + IS6 0 (0%) 2 (0.3%) 0 (0%) 0 (0%)
    IS1 + IS5 0 (0%) 0 (0%) 1 (1.5%) 0 (0%)
    IS1 + IS6 0 (0%) 2 (0.3%) 2 (3.1%) 4 (0.8%)
    IS1 + IS6 + IS1380 + IS91 0 (0%) 1 (0.2%) 0 (0%) 0 (0%)
    IS1 + IS91 + IS6 0 (0%) 0 (0%) 0 (0%) 1 (0.2%)
    IS1 + ISKRA4 0 (0%) 2 (0.3%) 0 (0%) 0 (0%)
    IS1 + ISKRA4 + IS91 0 (0%) 2 (0.3%) 0 (0%) 0 (0%)
    IS1 + ISNCY 0 (0%) 0 (0%) 0 (0%) 4 (0.8%)
    IS1 + new + IS6 + IS3 0 (0%) 2 (0.3%) 0 (0%) 0 (0%)
    IS110 0 (0%) 12 (2.1%) 1 (1.5%) 8 (1.6%)
    IS110 + IS1 + IS6 + new 0 (0%) 1 (0.2%) 0 (0%) 0 (0%)
    IS110 + IS1 + ISNCY + IS5 0 (0%) 0 (0%) 0 (0%) 1 (0.2%)
    IS110 + IS3 0 (0%) 1 (0.2%) 0 (0%) 0 (0%)
    IS110 + IS4 0 (0%) 0 (0%) 0 (0%) 1 (0.2%)
    IS110 + IS5 0 (0%) 1 (0.2%) 0 (0%) 0 (0%)
    IS110 + IS6 0 (0%) 7 (1.2%) 0 (0%) 1 (0.2%)
    IS110 + IS6 + IS3 0 (0%) 2 (0.3%) 0 (0%) 2 (0.4%)
    IS110 + IS6 + IS91 0 (0%) 0 (0%) 0 (0%) 3 (0.6%)
    IS110 + IS66 + IS3 0 (0%) 0 (0%) 0 (0%) 1 (0.2%)
    IS110 + IS66 + IS5 0 (0%) 0 (0%) 1 (1.5%) 0 (0%)
    IS110 + IS91 + IS6 0 (0%) 5 (0.9%) 0 (0%) 0 (0%)
    IS110 + ISNCY 0 (0%) 0 (0%) 0 (0%) 6 (1.2%)
    IS110 + ISNCY + IS4 0 (0%) 3 (0.5%) 0 (0%) 0 (0%)
    IS110 + new + IS6 + IS1380 0 (0%) 1 (0.2%) 0 (0%) 0 (0%)
    IS1380 0 (0%) 10 (1.7%) 1 (1.5%) 3 (0.6%)
    IS1380 + IS3 1 (13%) 0 (0%) 3 (4.6%) 2 (0.4%)
    IS1380 + IS3 + IS6 0 (0%) 1 (0.2%) 0 (0%) 0 (0%)
    IS1380 + IS6 0 (0%) 1 (0.2%) 0 (0%) 1 (0.2%)
    IS1380 + IS6 + IS5 + IS256 0 (0%) 1 (0.2%) 0 (0%) 0 (0%)
    IS200/IS605 0 (0%) 3 (0.5%) 1 (1.5%) 7 (1.4%)
    IS200/IS605 + IS1 + IS3 0 (0%) 1 (0.2%) 0 (0%) 0 (0%)
    IS200/IS605 + IS66 0 (0%) 6 (1.0%) 0 (0%) 0 (0%)
    IS21 0 (0%) 7 (1.2%) 2 (3.1%) 5 (1.0%)
    IS21 + IS1 + IS3 0 (0%) 0 (0%) 0 (0%) 1 (0.2%)
    IS21 + IS3 0 (0%) 2 (0.3%) 0 (0%) 5 (1.0%)
    IS21 + ISNCY 0 (0%) 1 (0.2%) 0 (0%) 0 (0%)
    IS256 0 (0%) 1 (0.2%) 0 (0%) 9 (1.8%)
    IS256 + IS4 0 (0%) 0 (0%) 0 (0%) 1 (0.2%)
    IS256 + IS6 + IS4 0 (0%) 0 (0%) 0 (0%) 2 (0.4%)
    IS256 + IS6 + ISNCY + IS5 0 (0%) 0 (0%) 0 (0%) 2 (0.4%)
    IS3 0 (0%) 50 (8.5%) 10 (15%) 72 (14%)
    IS3 + IS1 0 (0%) 1 (0.2%) 1 (1.5%) 2 (0.4%)
    IS3 + IS110 0 (0%) 0 (0%) 0 (0%) 2 (0.4%)
    IS3 + IS110 + ISNCY 0 (0%) 0 (0%) 0 (0%) 1 (0.2%)
    IS3 + IS1380 0 (0%) 0 (0%) 1 (1.5%) 0 (0%)
    IS3 + IS21 0 (0%) 0 (0%) 0 (0%) 8 (1.6%)
    IS3 + IS256 0 (0%) 0 (0%) 0 (0%) 1 (0.2%)
    IS3 + IS4 + IS6 + IS91 0 (0%) 0 (0%) 0 (0%) 1 (0.2%)
    IS3 + IS5 0 (0%) 1 (0.2%) 0 (0%) 0 (0%)
    IS3 + IS5 + IS6 0 (0%) 1 (0.2%) 0 (0%) 0 (0%)
    IS3 + IS6 0 (0%) 1 (0.2%) 2 (3.1%) 0 (0%)
    IS3 + IS6 + IS4 + IS91 0 (0%) 0 (0%) 0 (0%) 1 (0.2%)
    IS3 + IS6 + IS91 0 (0%) 0 (0%) 2 (3.1%) 0 (0%)
    IS3 + IS91 0 (0%) 8 (1.4%) 0 (0%) 0 (0%)
    IS3 + ISNCY + IS110 0 (0%) 3 (0.5%) 0 (0%) 0 (0%)
    IS3 + new + IS200/IS605 + IS110 + IS66 0 (0%) 0 (0%) 0 (0%) 1 (0.2%)
    IS4 0 (0%) 1 (0.2%) 0 (0%) 1 (0.2%)
    IS4 + IS256 0 (0%) 0 (0%) 0 (0%) 1 (0.2%)
    IS4 + IS6 0 (0%) 1 (0.2%) 0 (0%) 1 (0.2%)
    IS4 + IS6 + IS91 0 (0%) 1 (0.2%) 0 (0%) 6 (1.2%)
    IS4 + ISNCY + IS3 0 (0%) 0 (0%) 0 (0%) 1 (0.2%)
    IS4 + new + IS1380 0 (0%) 0 (0%) 0 (0%) 1 (0.2%)
    IS481 + ISNCY + IS6 0 (0%) 0 (0%) 0 (0%) 1 (0.2%)
    IS5 0 (0%) 15 (2.6%) 3 (4.6%) 28 (5.6%)
    IS5 + IS1 0 (0%) 0 (0%) 0 (0%) 1 (0.2%)
    IS5 + IS110 + IS1 + new 0 (0%) 0 (0%) 0 (0%) 1 (0.2%)
    IS5 + IS110 + IS3 + IS66 + IS256 0 (0%) 0 (0%) 0 (0%) 2 (0.4%)
    IS5 + IS3 1 (13%) 0 (0%) 0 (0%) 2 (0.4%)
    IS5 + IS30 0 (0%) 0 (0%) 0 (0%) 1 (0.2%)
    IS5 + IS6 0 (0%) 4 (0.7%) 0 (0%) 5 (1.0%)
    IS5 + IS6 + IS1 0 (0%) 0 (0%) 0 (0%) 2 (0.4%)
    IS5 + IS66 0 (0%) 0 (0%) 0 (0%) 6 (1.2%)
    IS5 + ISNCY 0 (0%) 0 (0%) 0 (0%) 1 (0.2%)
    IS5 + ISNCY + IS256 + IS66 + IS3 0 (0%) 0 (0%) 0 (0%) 1 (0.2%)
    IS5 + ISNCY + IS6 0 (0%) 0 (0%) 0 (0%) 1 (0.2%)
    IS6 6 (75%) 32 (5.5%) 4 (6.2%) 77 (15%)
    IS6 + IS1 0 (0%) 9 (1.5%) 0 (0%) 5 (1.0%)
    IS6 + IS1 + IS91 0 (0%) 0 (0%) 0 (0%) 1 (0.2%)
    IS6 + IS1 + new 0 (0%) 1 (0.2%) 0 (0%) 0 (0%)
    IS6 + IS110 0 (0%) 3 (0.5%) 3 (4.6%) 1 (0.2%)
    IS6 + IS110 + IS91 0 (0%) 0 (0%) 0 (0%) 1 (0.2%)
    IS6 + IS110 + new + IS3 + IS5 0 (0%) 0 (0%) 0 (0%) 3 (0.6%)
    IS6 + IS1380 0 (0%) 2 (0.3%) 0 (0%) 0 (0%)
    IS6 + IS1380 + IS3 0 (0%) 0 (0%) 0 (0%) 1 (0.2%)
    IS6 + IS21 + IS3 0 (0%) 2 (0.3%) 0 (0%) 0 (0%)
    IS6 + IS256 + ISNCY + IS5 0 (0%) 0 (0%) 0 (0%) 1 (0.2%)
    IS6 + IS3 0 (0%) 8 (1.4%) 2 (3.1%) 4 (0.8%)
    IS6 + IS3 + IS1 0 (0%) 3 (0.5%) 0 (0%) 0 (0%)
    IS6 + IS3 + IS1380 0 (0%) 1 (0.2%) 0 (0%) 0 (0%)
    IS6 + IS3 + IS91 0 (0%) 0 (0%) 0 (0%) 1 (0.2%)
    IS6 + IS4 0 (0%) 2 (0.3%) 0 (0%) 6 (1.2%)
    IS6 + IS4 + IS91 0 (0%) 1 (0.2%) 0 (0%) 4 (0.8%)
    IS6 + IS481 0 (0%) 0 (0%) 0 (0%) 3 (0.6%)
    IS6 + IS5 0 (0%) 0 (0%) 1 (1.5%) 4 (0.8%)
    IS6 + IS66 0 (0%) 3 (0.5%) 0 (0%) 0 (0%)
    IS6 + IS66 + IS91 + IS110 0 (0%) 0 (0%) 0 (0%) 1 (0.2%)
    IS6 + IS91 0 (0%) 3 (0.5%) 2 (3.1%) 7 (1.4%)
    IS6 + IS91 + IS110 0 (0%) 2 (0.3%) 0 (0%) 1 (0.2%)
    IS6 + ISL3 0 (0%) 0 (0%) 2 (3.1%) 0 (0%)
    IS6 + ISNCY 0 (0%) 3 (0.5%) 0 (0%) 2 (0.4%)
    IS6 + ISNCY + IS3 + IS21 + IS110 0 (0%) 0 (0%) 0 (0%) 2 (0.4%)
    IS6 + new 0 (0%) 4 (0.7%) 0 (0%) 0 (0%)
    IS630 0 (0%) 1 (0.2%) 0 (0%) 0 (0%)
    IS630 + IS1 0 (0%) 0 (0%) 0 (0%) 2 (0.4%)
    IS630 + IS5 0 (0%) 1 (0.2%) 0 (0%) 0 (0%)
    IS66 0 (0%) 13 (2.2%) 2 (3.1%) 19 (3.8%)
    IS66 + IS110 + IS3 + IS200/IS605 0 (0%) 0 (0%) 0 (0%) 2 (0.4%)
    IS66 + IS3 0 (0%) 0 (0%) 0 (0%) 1 (0.2%)
    IS66 + IS5 0 (0%) 5 (0.9%) 0 (0%) 2 (0.4%)
    IS66 + IS5 + IS3 + IS1 0 (0%) 0 (0%) 0 (0%) 2 (0.4%)
    IS66 + IS6 0 (0%) 4 (0.7%) 0 (0%) 1 (0.2%)
    IS66 + ISNCY + IS110 0 (0%) 1 (0.2%) 0 (0%) 0 (0%)
    IS91 0 (0%) 90 (15%) 0 (0%) 21 (4.2%)
    IS91 + IS1 + IS3 0 (0%) 5 (0.9%) 0 (0%) 1 (0.2%)
    IS91 + IS1 + IS6 0 (0%) 0 (0%) 0 (0%) 1 (0.2%)
    IS91 + IS110 0 (0%) 1 (0.2%) 0 (0%) 2 (0.4%)
    IS91 + IS6 0 (0%) 27 (4.6%) 7 (11%) 8 (1.6%)
    IS91 + IS6 + IS1 0 (0%) 0 (0%) 0 (0%) 2 (0.4%)
    IS91 + IS6 + IS110 0 (0%) 0 (0%) 0 (0%) 1 (0.2%)
    IS91 + IS6 + IS3 0 (0%) 2 (0.3%) 0 (0%) 0 (0%)
    IS91 + ISL3 0 (0%) 10 (1.7%) 0 (0%) 2 (0.4%)
    IS91 + ISNCY 0 (0%) 9 (1.5%) 0 (0%) 6 (1.2%)
    IS91 + new + IS256 0 (0%) 0 (0%) 1 (1.5%) 0 (0%)
    IS91 + new + IS6 + IS256 0 (0%) 0 (0%) 2 (3.1%) 0 (0%)
    ISAS1 + IS481 0 (0%) 0 (0%) 0 (0%) 1 (0.2%)
    ISKRA4 0 (0%) 1 (0.2%) 0 (0%) 1 (0.2%)
    ISL3 0 (0%) 53 (9.1%) 0 (0%) 5 (1.0%)
    ISL3 + IS1 + IS3 0 (0%) 14 (2.4%) 0 (0%) 3 (0.6%)
    ISL3 + IS1 + IS3 + IS5 0 (0%) 2 (0.3%) 0 (0%) 0 (0%)
    ISL3 + IS3 0 (0%) 1 (0.2%) 0 (0%) 0 (0%)
    ISNCY 0 (0%) 33 (5.6%) 2 (3.1%) 21 (4.2%)
    ISNCY + IS1 + IS3 + IS110 + IS630 + IS5 + IS6 + ISKRA4 0 (0%) 1 (0.2%) 0 (0%) 0 (0%)
    ISNCY + IS1 + IS3 + IS630 + IS5 + IS6 + ISKRA4 0 (0%) 1 (0.2%) 0 (0%) 0 (0%)
    ISNCY + IS110 0 (0%) 4 (0.7%) 0 (0%) 2 (0.4%)
    ISNCY + IS110 + IS6 0 (0%) 0 (0%) 0 (0%) 2 (0.4%)
    ISNCY + IS256 + IS66 + IS3 0 (0%) 0 (0%) 0 (0%) 4 (0.8%)
    ISNCY + IS3 0 (0%) 2 (0.3%) 0 (0%) 2 (0.4%)
    ISNCY + IS3 + IS1 0 (0%) 2 (0.3%) 0 (0%) 0 (0%)
    ISNCY + IS3 + IS21 0 (0%) 2 (0.3%) 0 (0%) 0 (0%)
    ISNCY + IS3 + IS6 0 (0%) 0 (0%) 2 (3.1%) 0 (0%)
    ISNCY + IS6 + IS91 + IS110 0 (0%) 1 (0.2%) 0 (0%) 0 (0%)
    new 0 (0%) 4 (0.7%) 0 (0%) 5 (1.0%)
    new + IS200/IS605 + IS6 + IS91 0 (0%) 0 (0%) 0 (0%) 1 (0.2%)
    new + IS5 0 (0%) 0 (0%) 0 (0%) 3 (0.6%)
    new + IS6 + IS1380 0 (0%) 1 (0.2%) 0 (0%) 0 (0%)
    new + IS6 + IS3 0 (0%) 1 (0.2%) 0 (0%) 0 (0%)
    new + ISNCY 0 (0%) 3 (0.5%) 0 (0%) 0 (0%)
total_flanking_IS 2 (2, 2) 1 (1, 2) 2 (1, 3) 1 (1, 3) 0.081
1 n (%); Median (Q1, Q3)
2 Fisher’s Exact Test for Count Data with simulated p-value (based on 2000 replicates); Kruskal-Wallis rank sum test