Table 2. Unadjusted Outcomes by Stage D Group
Characteristic Overall
N = 2,932
1
D1
N = 1,745
1
D2
N = 619
1
D3
N = 568
1
p-value2
All-cause mortality (30-day) 76 (2.6%) 36 (2.1%) 26 (4.2%) 14 (2.5%) 0.020
All-cause mortality (1-year) 171 (5.8%) 88 (5.0%) 54 (8.7%) 29 (5.1%) 0.004
Ischemic stroke (30-day) 12 (0.4%) 6 (0.3%) 4 (0.6%) 2 (0.4%) 0.516
Ischemic stroke (1-year) 14 (0.5%) 11 (0.6%) 2 (0.3%) 1 (0.2%) 0.454
Myocardial infarction (30-day) 12 (0.4%) 3 (0.2%) 8 (1.3%) 1 (0.2%) 0.002
Myocardial infarction (1-year) 22 (0.8%) 10 (0.6%) 5 (0.8%) 7 (1.2%) 0.243
Permanent pacemaker (30-day) 47 (1.6%) 27 (1.5%) 9 (1.5%) 11 (1.9%) 0.770
Permanent pacemaker (1-year) 47 (1.6%) 27 (1.5%) 9 (1.5%) 11 (1.9%) 0.770
Annular rupture 1 (<0.1%) 0 (0%) 1 (0.2%) 0 (0%) 0.405
Paravalvular AR (grade)



0.624
    None 2,489 (89%) 1,484 (88%) 514 (88%) 491 (90%)
    Trace/Mild 303 (11%) 185 (11%) 66 (11%) 52 (9.6%)
    Moderate 14 (0.5%) 8 (0.5%) 5 (0.9%) 1 (0.2%)
    Severe 1 (<0.1%) 1 (<0.1%) 0 (0%) 0 (0%)
Length of stay (days) 2.00 (1.00–3.00) 1.00 (1.00–3.00) 2.00 (1.00–4.00) 2.00 (1.00–3.00) <0.001
1 n (%); Median (Q1–Q3)
2 Fisher’s exact test; Kruskal-Wallis rank sum test