Characteristic
Booster Status
p-value2
All Participants (N=843,208)1 Booster
N = 758,118
1
No Booster
N = 85,090
1
Age — yr 68.5 ± 10.6 68.9 ± 10.5 64.8 ± 10.9 <0.001
Female sex — no. (%)


<0.001
    Female 448,272 (53%) 400,300 (53%) 47,972 (56%)
    Male 394,936 (47%) 357,818 (47%) 37,118 (44%)
Diabetes 244,746 (29%) 220,959 (29%) 23,787 (28%) <0.001
Chronic obstructive pulmonary disease 41,449 (4.9%) 37,291 (4.9%) 4,158 (4.9%) 0.7
Asthma 51,360 (6.1%) 46,198 (6.1%) 5,162 (6.1%) 0.8
Chronic kidney failure 51,636 (6.1%) 47,187 (6.2%) 4,449 (5.2%) <0.001
Hypertension 391,654 (46%) 358,517 (47%) 33,137 (39%) <0.001
Ischemic heart disease 142,742 (17%) 131,058 (17%) 11,684 (14%) <0.001
Chronic heart failure 37,297 (4.4%) 33,524 (4.4%) 3,773 (4.4%) 0.9
Obesity 278,097 (33%) 249,152 (33%) 28,945 (34%) <0.001
History of smoking 348,654 (41%) 314,226 (41%) 34,428 (40%) <0.001
1 Mean ± SD; n (%)
2 Wilcoxon rank sum test; Pearson’s Chi-squared test