Case-control Analysis for Risk Factors of Childhood Blood Level

Author

ICMR

Part 3. Multivariable analysis for adjusted associations with risk factors

The causal graph of risk factors for high blood lead levels is complex with multiple interrelated factors (shown below). We will build a multivariable model to identify the risk factors for blood lead levels, while adjusting for potential confounders.

A. Household construction characteristics

Characteristic N Adjusted OR1 95% CI p-value % exposed cases PAF (%)
Years of construction of current house 174




    Less than 10 years



    More than 10 years
1.52 0.81, 2.88 0.2 57.1 19.7
PSU Rural/Urban 174




    Rural



    Urban
3.96 1.78, 9.33 0.001

Wealth Index 174




    Highest



    Higher
0.58 0.16, 2.08 0.4

    Middle
0.46 0.13, 1.58 0.2

    Lower
0.72 0.22, 2.37 0.6

    Lowest
0.87 0.29, 2.56 0.8

1 Adjusted for rural/urban and wealth index
Abbreviations: CI = Confidence Interval, OR = Odds Ratio
Characteristic N Adjusted OR1 95% CI p-value % exposed cases PAF (%)
Visible peeling paint in current house 173




    No



    Yes
0.98 0.48, 1.97
0.9
40.5 -1
PSU Rural/Urban 173




    Rural



    Urban
4.35 1.90, 10.6 <0.001

Wealth Index 173




    Highest



    Higher
0.46 0.12, 1.65 0.2

    Middle
0.45 0.13, 1.56 0.2

    Lower
0.81 0.24, 2.65 0.7

    Lowest
0.89 0.29, 2.66 0.8

1 Adjusted for rural/urban and wealth index
Abbreviations: CI = Confidence Interval, OR = Odds Ratio
Characteristic N Adjusted OR1 95% CI p-value % exposed cases PAF (%)
paint_type_current_hh 175




    No paint/Cement paint



    Distemper
1.26 0.46, 3.53 0.7 29.8 6.2
    Chuna or similar
1.55 0.63, 4.00 0.4 39.3 13.9
    Emulsion
4.88 1.17, 23.4 0.036 16.7 13.2
PSU Rural/Urban 175




    Rural



    Urban
3.89 1.66, 9.66 0.002

Wealth Index 175




    Highest



    Higher
0.57 0.15, 2.15 0.4

    Middle
0.53 0.14, 1.95 0.3

    Lower
1.00 0.29, 3.44
0.9


    Lowest
1.20 0.38, 3.84 0.8

1 Adjusted for rural/urban and wealth index
Abbreviations: CI = Confidence Interval, OR = Odds Ratio
Characteristic N Adjusted OR1 95% CI p-value % exposed cases PAF (%)
Primary flooring type in household 93




    Non-soil-contact



    Soil-contact
3.91 1.61, 10.1 0.003 35.7 26.6
PSU Rural/Urban 93




    Rural



    Urban
3.16 0.85, 13.3 0.10

Wealth Index 93




    Highest



    Higher
0.91 0.05, 15.1
0.9


    Middle
0.93 0.11, 9.27
0.9


    Lower
1.71 0.19, 18.0 0.6

    Lowest
1.06 0.14, 9.85
0.9


1 Adjusted for rural/urban and wealth index
Abbreviations: CI = Confidence Interval, OR = Odds Ratio
Characteristic N Adjusted OR1 95% CI p-value % exposed cases PAF (%)
Smoking inside household 176




    No



    Yes
1.79 0.95, 3.45 0.076 56 24.7
PSU Rural/Urban 176




    Rural



    Urban
4.25 1.91, 10.1 <0.001

Wealth Index 176




    Highest



    Higher
0.52 0.14, 1.84 0.3

    Middle
0.40 0.11, 1.42 0.2

    Lower
0.76 0.23, 2.49 0.7

    Lowest
0.78 0.26, 2.33 0.7

1 Adjusted for rural/urban and wealth index
Abbreviations: CI = Confidence Interval, OR = Odds Ratio
Characteristic N Adjusted OR1 95% CI p-value % exposed cases PAF (%)
Car/machine repair activity near household 173




    No



    Yes
1.62 0.36, 7.60 0.5 6 2.3
PSU Rural/Urban 173




    Rural



    Urban
4.53 2.01, 11.0 <0.001

Wealth Index 173




    Highest



    Higher
0.44 0.12, 1.58 0.2

    Middle
0.35 0.09, 1.25 0.11

    Lower
0.78 0.22, 2.61 0.7

    Lowest
0.78 0.25, 2.39 0.7

1 Adjusted for rural/urban and wealth index
Abbreviations: CI = Confidence Interval, OR = Odds Ratio
Characteristic N Adjusted OR1 95% CI p-value % exposed cases PAF (%)
Presence of old metal pipes 174




    No



    Yes
4.03 1.41, 13.5 0.014 19 14.3
PSU Rural/Urban 174




    Rural



    Urban
3.70 1.65, 8.76 0.002

Wealth Index 174




    Highest



    Higher
0.36 0.09, 1.35 0.14

    Middle
0.39 0.11, 1.39 0.2

    Lower
0.76 0.23, 2.49 0.6

    Lowest
0.83 0.27, 2.47 0.7

1 Adjusted for rural/urban and wealth index
Abbreviations: CI = Confidence Interval, OR = Odds Ratio