Note: I will finish everything by Sunday
GWAS or Genome-Wide Association Study is a dataset contains genetic data from individuals is used to identify associations between genetic variants (SNPs) and traits (e.g., height, disease risk).
This Data set is yseful because it is used in disease research, personalized medicine, and genetics.
Genome, Chromosome, Gene, and Nucleotide are all related to DNA.
While Genome is a complete set of DNA in an organism, Gene is a segment of DNA that codes the protein. Chromosome is a long DNA molecule containing genes and Nucleotide is the fundamental building block of nucleic acids, such as DNA and RNA
Allele is a specific version of a gene or SNP.
SNP stands for Signle Nucleotide Polymorphism which is a single base variation in DNA. A SNP (rs12345) at a position in the genome may have two possible alleles and each person inherits two copies of each SNP (one from each parent which can ether be Homozygous or Heterozygous
The association between SNPs and traits is typically tested using a linear or logistic regression mode: Y = beta0 + Beta1*X1
The null hyppothesys is when beta equal to 0 to show that SNPs have no effect.The hypothesis is when bta is not equal to 0, showing that SNP have the effect with the trait
Because GWAS dataset is too big that p = 0.05 is not significant anymore. It would show the false discovery
FWER is more conservative and also having a strict threshold which make it to be a strong control of false positive and widely accepted in GWAS publications compare to the FDR method.
Dissecting the genetics of complex traits using summary association statistics
Complex traits which traits influenced by many genetic variants and environmental factors
Review recent progress on statistical methods that leverage summary association data to gain insights into the genetic basis of complex traits and diseases.
# Built-in GWAS demo dataset (gwasResults) — loads instantly
data(gwasResults)
snp_clean <- gwasResults %>%
rename(SNP = SNP, CHR = CHR, BP = BP, P = P) %>%
filter(!is.na(P), P > 0) %>%
arrange(P)
# Step 3: Histogram
ggplot(snp_clean, aes(x = P)) +
geom_histogram(bins = 50, fill = "#2196F3", color = "white") +
labs(title = "P-value Distribution — GWAS Demo Data",
x = "P-value", y = "Count") +
theme_minimal()
#### FDER and FDR
# Step 4: Apply FWER & FDR
snp_clean <- snp_clean %>%
mutate(
p_bonferroni = p.adjust(P, method = "bonferroni"),
p_BH = p.adjust(P, method = "BH"),
sig_bonferroni = p_bonferroni < 0.05,
sig_FDR = p_BH < 0.05,
sig_GWAS = P < 5e-8
)
print (snp_clean)
## SNP CHR BP P p_bonferroni p_BH sig_bonferroni
## 1 rs3057 3 366 4.438922e-09 7.310904e-05 4.286281e-05 TRUE
## 2 rs3050 3 359 7.803872e-09 1.285298e-04 4.286281e-05 TRUE
## 3 rs3056 3 365 7.807433e-09 1.285884e-04 4.286281e-05 TRUE
## 4 rs3060 3 369 2.488724e-08 4.098929e-04 8.804538e-05 TRUE
## 5 rs3040 3 349 2.672902e-08 4.402269e-04 8.804538e-05 TRUE
## 6 rs3054 3 363 3.892246e-08 6.410528e-04 1.068421e-04 TRUE
## 7 rs3051 3 360 6.459032e-08 1.063803e-03 1.519718e-04 TRUE
## 8 rs3052 3 361 1.018498e-07 1.677467e-03 1.925831e-04 TRUE
## 9 rs3055 3 364 1.173634e-07 1.932976e-03 1.925831e-04 TRUE
## 10 rs3047 3 356 1.237451e-07 2.038082e-03 1.925831e-04 TRUE
## 11 rs3039 3 348 1.291335e-07 2.126829e-03 1.925831e-04 TRUE
## 12 rs3049 3 358 1.575144e-07 2.594263e-03 1.925831e-04 TRUE
## 13 rs3048 3 357 1.578447e-07 2.599702e-03 1.925831e-04 TRUE
## 14 rs3053 3 362 1.637015e-07 2.696164e-03 1.925831e-04 TRUE
## 15 rs3044 3 353 2.182527e-07 3.594623e-03 2.396415e-04 TRUE
## 16 rs3045 3 354 2.715654e-07 4.472682e-03 2.777781e-04 TRUE
## 17 rs3041 3 350 2.946537e-07 4.852947e-03 2.777781e-04 TRUE
## 18 rs3046 3 355 3.035826e-07 5.000005e-03 2.777781e-04 TRUE
## 19 rs3061 3 370 3.759351e-07 6.191651e-03 3.258764e-04 TRUE
## 20 rs3058 3 367 4.739185e-07 7.805437e-03 3.902719e-04 TRUE
## 21 rs3059 3 368 5.101074e-07 8.401470e-03 4.000700e-04 TRUE
## 22 rs3042 3 351 5.475278e-07 9.017782e-03 4.067937e-04 TRUE
## 23 rs3035 3 344 5.743707e-07 9.459885e-03 4.067937e-04 TRUE
## 24 rs3043 3 352 5.927777e-07 9.763049e-03 4.067937e-04 TRUE
## 25 rs3063 3 372 6.195479e-07 1.020395e-02 4.081581e-04 TRUE
## 26 rs3064 3 373 1.081160e-06 1.780671e-02 6.614120e-04 TRUE
## 27 rs3038 3 347 1.084282e-06 1.785812e-02 6.614120e-04 TRUE
## 28 rs3062 3 371 1.542880e-06 2.541123e-02 9.075441e-04 TRUE
## 29 rs3066 3 375 1.658165e-06 2.730998e-02 9.417234e-04 TRUE
## 30 rs3065 3 374 2.140884e-06 3.526036e-02 1.175345e-03 TRUE
## 31 rs3070 3 379 2.310487e-06 3.805372e-02 1.227539e-03 TRUE
## 32 rs3037 3 346 2.537116e-06 4.178631e-02 1.305822e-03 TRUE
## 33 rs3068 3 377 2.755368e-06 4.538090e-02 1.375179e-03 TRUE
## 34 rs3036 3 345 3.702689e-06 6.098329e-02 1.793626e-03 FALSE
## 35 rs3034 3 343 6.093931e-06 1.003670e-01 2.867630e-03 FALSE
## 36 rs3067 3 376 8.671423e-06 1.428183e-01 3.967176e-03 FALSE
## 37 rs3033 3 342 1.320982e-05 2.175658e-01 5.880156e-03 FALSE
## 38 rs3032 3 341 1.593872e-05 2.625108e-01 6.773669e-03 FALSE
## 39 rs3069 3 378 1.603965e-05 2.641731e-01 6.773669e-03 FALSE
## 40 rs3030 3 339 1.798130e-05 2.961521e-01 7.403802e-03 FALSE
## 41 rs13895 18 191 2.635363e-05 4.340444e-01 1.058645e-02 FALSE
## 42 rs3031 3 340 2.976909e-05 4.902970e-01 1.167374e-02 FALSE
## 43 rs11846 14 550 4.936848e-05 8.130988e-01 1.890928e-02 FALSE
## 44 rs3029 3 338 7.079979e-05 1.000000e+00 2.650165e-02 FALSE
## 45 rs3071 3 380 8.000464e-05 1.000000e+00 2.928170e-02 FALSE
## 46 rs3072 3 381 1.615214e-04 1.000000e+00 5.783169e-02 FALSE
## 47 rs3074 3 383 1.699519e-04 1.000000e+00 5.955550e-02 FALSE
## 48 rs92 1 92 2.388966e-04 1.000000e+00 8.197139e-02 FALSE
## 49 rs15860 21 469 3.301252e-04 1.000000e+00 1.109625e-01 FALSE
## 50 rs1959 2 459 3.734785e-04 1.000000e+00 1.230238e-01 FALSE
## 51 rs4064 4 333 3.825743e-04 1.000000e+00 1.235490e-01 FALSE
## 52 rs574 1 574 4.050434e-04 1.000000e+00 1.282897e-01 FALSE
## 53 rs9901 11 572 4.330799e-04 1.000000e+00 1.345816e-01 FALSE
## 54 rs9820 11 491 4.848987e-04 1.000000e+00 1.478941e-01 FALSE
## 55 rs3073 3 382 5.673970e-04 1.000000e+00 1.699096e-01 FALSE
## 56 rs3028 3 337 5.787863e-04 1.000000e+00 1.702252e-01 FALSE
## 57 rs6636 7 258 5.970318e-04 1.000000e+00 1.725108e-01 FALSE
## 58 rs5287 5 611 6.881878e-04 1.000000e+00 1.954216e-01 FALSE
## 59 rs5847 6 294 7.331292e-04 1.000000e+00 2.046549e-01 FALSE
## 60 rs15234 20 396 7.607634e-04 1.000000e+00 2.088296e-01 FALSE
## 61 rs7641 8 479 8.476523e-04 1.000000e+00 2.288661e-01 FALSE
## 62 rs14370 19 94 8.689296e-04 1.000000e+00 2.308269e-01 FALSE
## 63 rs7698 8 536 8.979898e-04 1.000000e+00 2.322708e-01 FALSE
## 64 rs14423 19 147 9.025703e-04 1.000000e+00 2.322708e-01 FALSE
## 65 rs15761 21 370 1.031227e-03 1.000000e+00 2.612972e-01 FALSE
## 66 rs12653 16 127 1.193328e-03 1.000000e+00 2.977897e-01 FALSE
## 67 rs6896 7 518 1.231863e-03 1.000000e+00 3.028177e-01 FALSE
## 68 rs4962 5 286 1.256448e-03 1.000000e+00 3.037469e-01 FALSE
## 69 rs1293 1 1293 1.272528e-03 1.000000e+00 3.037469e-01 FALSE
## 70 rs8349 9 437 1.345361e-03 1.000000e+00 3.165442e-01 FALSE
## 71 rs117 1 117 1.380844e-03 1.000000e+00 3.198040e-01 FALSE
## 72 rs12180 15 262 1.399034e-03 1.000000e+00 3.198040e-01 FALSE
## 73 rs472 1 472 1.433898e-03 1.000000e+00 3.198040e-01 FALSE
## 74 rs8682 10 49 1.458429e-03 1.000000e+00 3.198040e-01 FALSE
## 75 rs5875 6 322 1.497587e-03 1.000000e+00 3.198040e-01 FALSE
## 76 rs10628 12 625 1.529471e-03 1.000000e+00 3.198040e-01 FALSE
## 77 rs1398 1 1398 1.533849e-03 1.000000e+00 3.198040e-01 FALSE
## 78 rs1811 2 311 1.544297e-03 1.000000e+00 3.198040e-01 FALSE
## 79 rs10131 12 128 1.562949e-03 1.000000e+00 3.198040e-01 FALSE
## 80 rs80 1 80 1.570554e-03 1.000000e+00 3.198040e-01 FALSE
## 81 rs6203 6 650 1.572807e-03 1.000000e+00 3.198040e-01 FALSE
## 82 rs12463 15 545 1.640321e-03 1.000000e+00 3.294644e-01 FALSE
## 83 rs2015 2 515 1.703130e-03 1.000000e+00 3.345552e-01 FALSE
## 84 rs10818 13 160 1.706292e-03 1.000000e+00 3.345552e-01 FALSE
## 85 rs10606 12 603 1.885627e-03 1.000000e+00 3.653679e-01 FALSE
## 86 rs16074 22 139 1.978708e-03 1.000000e+00 3.789456e-01 FALSE
## 87 rs11234 13 576 2.232639e-03 1.000000e+00 4.226616e-01 FALSE
## 88 rs110 1 110 2.272966e-03 1.000000e+00 4.244612e-01 FALSE
## 89 rs5067 5 391 2.335115e-03 1.000000e+00 4.244612e-01 FALSE
## 90 rs4371 4 640 2.338519e-03 1.000000e+00 4.244612e-01 FALSE
## 91 rs13077 16 551 2.355907e-03 1.000000e+00 4.244612e-01 FALSE
## 92 rs332 1 332 2.378107e-03 1.000000e+00 4.244612e-01 FALSE
## 93 rs12826 16 300 2.396776e-03 1.000000e+00 4.244612e-01 FALSE
## 94 rs9486 11 157 2.561032e-03 1.000000e+00 4.471632e-01 FALSE
## 95 rs10699 13 41 2.579266e-03 1.000000e+00 4.471632e-01 FALSE
## 96 rs11110 13 452 2.679336e-03 1.000000e+00 4.558482e-01 FALSE
## 97 rs7701 8 539 2.684716e-03 1.000000e+00 4.558482e-01 FALSE
## 98 rs5386 5 710 2.800816e-03 1.000000e+00 4.690449e-01 FALSE
## 99 rs4129 4 398 2.819396e-03 1.000000e+00 4.690449e-01 FALSE
## 100 rs8219 9 307 3.109833e-03 1.000000e+00 5.075905e-01 FALSE
## 101 rs14108 18 404 3.112729e-03 1.000000e+00 5.075905e-01 FALSE
## 102 rs14397 19 121 3.173696e-03 1.000000e+00 5.121093e-01 FALSE
## 103 rs3027 3 336 3.202626e-03 1.000000e+00 5.121093e-01 FALSE
## 104 rs8449 9 537 3.279057e-03 1.000000e+00 5.192891e-01 FALSE
## 105 rs10768 13 110 3.322501e-03 1.000000e+00 5.211580e-01 FALSE
## 106 rs5553 5 877 3.415338e-03 1.000000e+00 5.236168e-01 FALSE
## 107 rs9589 11 260 3.462046e-03 1.000000e+00 5.236168e-01 FALSE
## 108 rs537 1 537 3.467704e-03 1.000000e+00 5.236168e-01 FALSE
## 109 rs11148 13 490 3.472484e-03 1.000000e+00 5.236168e-01 FALSE
## 110 rs10501 12 498 3.498503e-03 1.000000e+00 5.236168e-01 FALSE
## 111 rs12590 16 64 3.528929e-03 1.000000e+00 5.236168e-01 FALSE
## 112 rs840 1 840 3.591406e-03 1.000000e+00 5.281291e-01 FALSE
## 113 rs1678 2 178 3.642740e-03 1.000000e+00 5.304070e-01 FALSE
## 114 rs9349 11 20 3.671305e-03 1.000000e+00 5.304070e-01 FALSE
## 115 rs6529 7 151 3.712363e-03 1.000000e+00 5.316749e-01 FALSE
## 116 rs15216 20 378 3.901060e-03 1.000000e+00 5.508062e-01 FALSE
## 117 rs7128 7 750 3.937200e-03 1.000000e+00 5.508062e-01 FALSE
## 118 rs35 1 35 3.948339e-03 1.000000e+00 5.508062e-01 FALSE
## 119 rs15125 20 287 3.979717e-03 1.000000e+00 5.508062e-01 FALSE
## 120 rs15112 20 274 4.142612e-03 1.000000e+00 5.651741e-01 FALSE
## 121 rs4532 4 801 4.152159e-03 1.000000e+00 5.651741e-01 FALSE
## 122 rs6578 7 200 4.231033e-03 1.000000e+00 5.697808e-01 FALSE
## 123 rs11464 14 168 4.255194e-03 1.000000e+00 5.697808e-01 FALSE
## 124 rs2087 2 587 4.321658e-03 1.000000e+00 5.711933e-01 FALSE
## 125 rs4456 4 725 4.361042e-03 1.000000e+00 5.711933e-01 FALSE
## 126 rs14707 19 431 4.369785e-03 1.000000e+00 5.711933e-01 FALSE
## 127 rs9115 10 482 4.421746e-03 1.000000e+00 5.734343e-01 FALSE
## 128 rs3099 3 408 4.479119e-03 1.000000e+00 5.759510e-01 FALSE
## 129 rs5732 6 179 4.511091e-03 1.000000e+00 5.759510e-01 FALSE
## 130 rs7086 7 708 4.554378e-03 1.000000e+00 5.770046e-01 FALSE
## 131 rs6870 7 492 4.639999e-03 1.000000e+00 5.833648e-01 FALSE
## 132 rs2891 3 200 4.739877e-03 1.000000e+00 5.844849e-01 FALSE
## 133 rs3426 3 735 4.740768e-03 1.000000e+00 5.844849e-01 FALSE
## 134 rs1512 2 12 4.755372e-03 1.000000e+00 5.844849e-01 FALSE
## 135 rs9610 11 281 4.988990e-03 1.000000e+00 6.080379e-01 FALSE
## 136 rs8166 9 254 5.029139e-03 1.000000e+00 6.080379e-01 FALSE
## 137 rs10730 13 72 5.057753e-03 1.000000e+00 6.080379e-01 FALSE
## 138 rs13584 17 463 5.181407e-03 1.000000e+00 6.158942e-01 FALSE
## 139 rs6359 6 806 5.197893e-03 1.000000e+00 6.158942e-01 FALSE
## 140 rs1641 2 141 5.327342e-03 1.000000e+00 6.223104e-01 FALSE
## 141 rs2129 2 629 5.327612e-03 1.000000e+00 6.223104e-01 FALSE
## 142 rs2693 3 2 5.621029e-03 1.000000e+00 6.416801e-01 FALSE
## 143 rs11166 13 508 5.634653e-03 1.000000e+00 6.416801e-01 FALSE
## 144 rs16234 22 299 5.641565e-03 1.000000e+00 6.416801e-01 FALSE
## 145 rs6990 7 612 5.696127e-03 1.000000e+00 6.416801e-01 FALSE
## 146 rs1134 1 1134 5.706670e-03 1.000000e+00 6.416801e-01 FALSE
## 147 rs7580 8 418 5.747615e-03 1.000000e+00 6.416801e-01 FALSE
## 148 rs16145 22 210 5.766160e-03 1.000000e+00 6.416801e-01 FALSE
## 149 rs7408 8 246 5.828218e-03 1.000000e+00 6.442332e-01 FALSE
## 150 rs2176 2 676 5.896285e-03 1.000000e+00 6.458266e-01 FALSE
## 151 rs13562 17 441 5.921057e-03 1.000000e+00 6.458266e-01 FALSE
## 152 rs8861 10 228 6.000759e-03 1.000000e+00 6.477157e-01 FALSE
## 153 rs15717 21 326 6.017031e-03 1.000000e+00 6.477157e-01 FALSE
## 154 rs14503 19 227 6.225460e-03 1.000000e+00 6.617471e-01 FALSE
## 155 rs7411 8 249 6.227735e-03 1.000000e+00 6.617471e-01 FALSE
## 156 rs5609 6 56 6.283026e-03 1.000000e+00 6.633425e-01 FALSE
## 157 rs2848 3 157 6.331014e-03 1.000000e+00 6.641516e-01 FALSE
## 158 rs4281 4 550 6.411641e-03 1.000000e+00 6.683527e-01 FALSE
## 159 rs6773 7 395 6.634794e-03 1.000000e+00 6.841532e-01 FALSE
## 160 rs5133 5 457 6.646297e-03 1.000000e+00 6.841532e-01 FALSE
## 161 rs14394 19 118 6.697866e-03 1.000000e+00 6.851792e-01 FALSE
## 162 rs947 1 947 6.921040e-03 1.000000e+00 6.931906e-01 FALSE
## 163 rs15537 21 146 6.937977e-03 1.000000e+00 6.931906e-01 FALSE
## 164 rs8948 10 315 6.996104e-03 1.000000e+00 6.931906e-01 FALSE
## 165 rs8108 9 196 7.022564e-03 1.000000e+00 6.931906e-01 FALSE
## 166 rs7522 8 360 7.030402e-03 1.000000e+00 6.931906e-01 FALSE
## 167 rs2449 2 949 7.058411e-03 1.000000e+00 6.931906e-01 FALSE
## 168 rs8777 10 144 7.235138e-03 1.000000e+00 6.931906e-01 FALSE
## 169 rs11337 14 41 7.251478e-03 1.000000e+00 6.931906e-01 FALSE
## 170 rs7506 8 344 7.261852e-03 1.000000e+00 6.931906e-01 FALSE
## 171 rs9125 10 492 7.265578e-03 1.000000e+00 6.931906e-01 FALSE
## 172 rs11526 14 230 7.268763e-03 1.000000e+00 6.931906e-01 FALSE
## 173 rs37 1 37 7.334147e-03 1.000000e+00 6.931906e-01 FALSE
## 174 rs1000 1 1000 7.417523e-03 1.000000e+00 6.931906e-01 FALSE
## 175 rs4666 4 935 7.446842e-03 1.000000e+00 6.931906e-01 FALSE
## 176 rs9184 10 551 7.514782e-03 1.000000e+00 6.931906e-01 FALSE
## 177 rs7067 7 689 7.551896e-03 1.000000e+00 6.931906e-01 FALSE
## 178 rs2413 2 913 7.574288e-03 1.000000e+00 6.931906e-01 FALSE
## 179 rs7183 8 21 7.591723e-03 1.000000e+00 6.931906e-01 FALSE
## 180 rs3260 3 569 7.698255e-03 1.000000e+00 6.931906e-01 FALSE
## 181 rs9174 10 541 7.731027e-03 1.000000e+00 6.931906e-01 FALSE
## 182 rs4689 5 13 7.833919e-03 1.000000e+00 6.931906e-01 FALSE
## 183 rs6859 7 481 7.845372e-03 1.000000e+00 6.931906e-01 FALSE
## 184 rs10557 12 554 7.867837e-03 1.000000e+00 6.931906e-01 FALSE
## 185 rs77 1 77 7.884739e-03 1.000000e+00 6.931906e-01 FALSE
## 186 rs6959 7 581 7.885663e-03 1.000000e+00 6.931906e-01 FALSE
## 187 rs2540 2 1040 7.975502e-03 1.000000e+00 6.931906e-01 FALSE
## 188 rs4917 5 241 7.990277e-03 1.000000e+00 6.931906e-01 FALSE
## 189 rs9567 11 238 8.001621e-03 1.000000e+00 6.931906e-01 FALSE
## 190 rs1634 2 134 8.029784e-03 1.000000e+00 6.931906e-01 FALSE
## 191 rs13658 17 537 8.107562e-03 1.000000e+00 6.931906e-01 FALSE
## 192 rs7545 8 383 8.173051e-03 1.000000e+00 6.931906e-01 FALSE
## 193 rs15584 21 193 8.191611e-03 1.000000e+00 6.931906e-01 FALSE
## 194 rs2604 2 1104 8.231374e-03 1.000000e+00 6.931906e-01 FALSE
## 195 rs2992 3 301 8.304643e-03 1.000000e+00 6.931906e-01 FALSE
## 196 rs9069 10 436 8.313354e-03 1.000000e+00 6.931906e-01 FALSE
## 197 rs15151 20 313 8.357261e-03 1.000000e+00 6.931906e-01 FALSE
## 198 rs12019 15 101 8.378597e-03 1.000000e+00 6.931906e-01 FALSE
## 199 rs8679 10 46 8.455582e-03 1.000000e+00 6.931906e-01 FALSE
## 200 rs10554 12 551 8.555726e-03 1.000000e+00 6.931906e-01 FALSE
## 201 rs9084 10 451 8.555729e-03 1.000000e+00 6.931906e-01 FALSE
## 202 rs5554 6 1 8.559862e-03 1.000000e+00 6.931906e-01 FALSE
## 203 rs4141 4 410 8.585181e-03 1.000000e+00 6.931906e-01 FALSE
## 204 rs10105 12 102 8.585967e-03 1.000000e+00 6.931906e-01 FALSE
## 205 rs10423 12 420 8.703583e-03 1.000000e+00 6.933992e-01 FALSE
## 206 rs10592 12 589 8.711643e-03 1.000000e+00 6.933992e-01 FALSE
## 207 rs9689 11 360 8.714854e-03 1.000000e+00 6.933992e-01 FALSE
## 208 rs12596 16 70 8.829885e-03 1.000000e+00 6.991741e-01 FALSE
## 209 rs7592 8 430 8.946207e-03 1.000000e+00 7.005502e-01 FALSE
## 210 rs764 1 764 8.982624e-03 1.000000e+00 7.005502e-01 FALSE
## 211 rs10229 12 226 8.995099e-03 1.000000e+00 7.005502e-01 FALSE
## 212 rs16289 22 354 9.047898e-03 1.000000e+00 7.005502e-01 FALSE
## 213 rs1152 1 1152 9.059939e-03 1.000000e+00 7.005502e-01 FALSE
## 214 rs5202 5 526 9.108286e-03 1.000000e+00 7.009975e-01 FALSE
## 215 rs6488 7 110 9.287180e-03 1.000000e+00 7.087777e-01 FALSE
## 216 rs8125 9 213 9.295445e-03 1.000000e+00 7.087777e-01 FALSE
## 217 rs3967 4 236 9.375227e-03 1.000000e+00 7.098770e-01 FALSE
## 218 rs11312 14 16 9.396065e-03 1.000000e+00 7.098770e-01 FALSE
## 219 rs2042 2 542 9.629518e-03 1.000000e+00 7.217785e-01 FALSE
## 220 rs5061 5 385 9.641242e-03 1.000000e+00 7.217785e-01 FALSE
## 221 rs13640 17 519 9.769497e-03 1.000000e+00 7.250098e-01 FALSE
## 222 rs6847 7 469 9.772446e-03 1.000000e+00 7.250098e-01 FALSE
## 223 rs15142 20 304 9.819743e-03 1.000000e+00 7.252519e-01 FALSE
## 224 rs13588 17 467 9.975806e-03 1.000000e+00 7.276867e-01 FALSE
## 225 rs5323 5 647 9.980008e-03 1.000000e+00 7.276867e-01 FALSE
## 226 rs8175 9 263 9.985258e-03 1.000000e+00 7.276867e-01 FALSE
## 227 rs6982 7 604 1.005813e-02 1.000000e+00 7.287733e-01 FALSE
## 228 rs13164 17 43 1.009828e-02 1.000000e+00 7.287733e-01 FALSE
## 229 rs14959 20 121 1.013291e-02 1.000000e+00 7.287733e-01 FALSE
## 230 rs10211 12 208 1.033935e-02 1.000000e+00 7.334691e-01 FALSE
## 231 rs4173 4 442 1.037076e-02 1.000000e+00 7.334691e-01 FALSE
## 232 rs3026 3 335 1.050925e-02 1.000000e+00 7.334691e-01 FALSE
## 233 rs4682 5 6 1.052211e-02 1.000000e+00 7.334691e-01 FALSE
## 234 rs8595 9 683 1.053015e-02 1.000000e+00 7.334691e-01 FALSE
## 235 rs14533 19 257 1.057508e-02 1.000000e+00 7.334691e-01 FALSE
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## 1595 rs1175 1 1175 8.908186e-02 1.000000e+00 9.198610e-01 FALSE
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## 1652 rs7844 8 682 9.302733e-02 1.000000e+00 9.268811e-01 FALSE
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## 1708 rs13048 16 522 9.669104e-02 1.000000e+00 9.268811e-01 FALSE
## 1709 rs7684 8 522 9.679680e-02 1.000000e+00 9.268811e-01 FALSE
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## 1715 rs9704 11 375 9.725695e-02 1.000000e+00 9.268811e-01 FALSE
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## 1720 rs12893 16 367 9.764779e-02 1.000000e+00 9.268811e-01 FALSE
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## 1744 rs12440 15 522 9.918838e-02 1.000000e+00 9.268811e-01 FALSE
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## 1749 rs3899 4 168 9.927718e-02 1.000000e+00 9.268811e-01 FALSE
## 1750 rs4322 4 591 9.927862e-02 1.000000e+00 9.268811e-01 FALSE
## 1751 rs8805 10 172 9.929410e-02 1.000000e+00 9.268811e-01 FALSE
## 1752 rs16368 22 433 9.936380e-02 1.000000e+00 9.268811e-01 FALSE
## 1753 rs8709 10 76 9.951495e-02 1.000000e+00 9.268811e-01 FALSE
## 1754 rs14424 19 148 9.951613e-02 1.000000e+00 9.268811e-01 FALSE
## 1755 rs5850 6 297 9.961318e-02 1.000000e+00 9.268811e-01 FALSE
## 1756 rs439 1 439 9.964059e-02 1.000000e+00 9.268811e-01 FALSE
## 1757 rs2975 3 284 9.983246e-02 1.000000e+00 9.268811e-01 FALSE
## 1758 rs13183 17 62 9.985686e-02 1.000000e+00 9.268811e-01 FALSE
## 1759 rs13088 16 562 9.991800e-02 1.000000e+00 9.268811e-01 FALSE
## 1760 rs10325 12 322 1.001187e-01 1.000000e+00 9.268811e-01 FALSE
## 1761 rs4118 4 387 1.001247e-01 1.000000e+00 9.268811e-01 FALSE
## 1762 rs10904 13 246 1.001273e-01 1.000000e+00 9.268811e-01 FALSE
## 1763 rs658 1 658 1.002294e-01 1.000000e+00 9.268811e-01 FALSE
## 1764 rs13014 16 488 1.002425e-01 1.000000e+00 9.268811e-01 FALSE
## 1765 rs3120 3 429 1.002996e-01 1.000000e+00 9.268811e-01 FALSE
## 1766 rs16446 22 511 1.003002e-01 1.000000e+00 9.268811e-01 FALSE
## 1767 rs14846 20 8 1.003416e-01 1.000000e+00 9.268811e-01 FALSE
## 1768 rs1080 1 1080 1.003542e-01 1.000000e+00 9.268811e-01 FALSE
## 1769 rs7804 8 642 1.003643e-01 1.000000e+00 9.268811e-01 FALSE
## 1770 rs1240 1 1240 1.003700e-01 1.000000e+00 9.268811e-01 FALSE
## 1771 rs11097 13 439 1.004441e-01 1.000000e+00 9.268811e-01 FALSE
## 1772 rs2880 3 189 1.004616e-01 1.000000e+00 9.268811e-01 FALSE
## 1773 rs12503 15 585 1.006209e-01 1.000000e+00 9.268811e-01 FALSE
## 1774 rs14627 19 351 1.006652e-01 1.000000e+00 9.268811e-01 FALSE
## 1775 rs12458 15 540 1.006723e-01 1.000000e+00 9.268811e-01 FALSE
## 1776 rs15395 21 4 1.006991e-01 1.000000e+00 9.268811e-01 FALSE
## 1777 rs3635 3 944 1.007126e-01 1.000000e+00 9.268811e-01 FALSE
## 1778 rs7528 8 366 1.007748e-01 1.000000e+00 9.268811e-01 FALSE
## 1779 rs9342 11 13 1.009128e-01 1.000000e+00 9.268811e-01 FALSE
## 1780 rs4287 4 556 1.009254e-01 1.000000e+00 9.268811e-01 FALSE
## 1781 rs13434 17 313 1.009443e-01 1.000000e+00 9.268811e-01 FALSE
## 1782 rs4239 4 508 1.009832e-01 1.000000e+00 9.268811e-01 FALSE
## 1783 rs1516 2 16 1.009988e-01 1.000000e+00 9.268811e-01 FALSE
## 1784 rs16395 22 460 1.010761e-01 1.000000e+00 9.268811e-01 FALSE
## 1785 rs13962 18 258 1.011701e-01 1.000000e+00 9.268811e-01 FALSE
## 1786 rs10759 13 101 1.012714e-01 1.000000e+00 9.268811e-01 FALSE
## 1787 rs13350 17 229 1.013350e-01 1.000000e+00 9.268811e-01 FALSE
## 1788 rs3587 3 896 1.013499e-01 1.000000e+00 9.268811e-01 FALSE
## 1789 rs8093 9 181 1.014480e-01 1.000000e+00 9.268811e-01 FALSE
## 1790 rs12346 15 428 1.014556e-01 1.000000e+00 9.268811e-01 FALSE
## 1791 rs12003 15 85 1.015155e-01 1.000000e+00 9.268811e-01 FALSE
## 1792 rs16126 22 191 1.017636e-01 1.000000e+00 9.268811e-01 FALSE
## 1793 rs14043 18 339 1.018020e-01 1.000000e+00 9.268811e-01 FALSE
## 1794 rs13847 18 143 1.018183e-01 1.000000e+00 9.268811e-01 FALSE
## 1795 rs6710 7 332 1.018589e-01 1.000000e+00 9.268811e-01 FALSE
## 1796 rs5828 6 275 1.019795e-01 1.000000e+00 9.268811e-01 FALSE
## 1797 rs6034 6 481 1.020876e-01 1.000000e+00 9.268811e-01 FALSE
## 1798 rs9678 11 349 1.021958e-01 1.000000e+00 9.268811e-01 FALSE
## 1799 rs13292 17 171 1.022020e-01 1.000000e+00 9.268811e-01 FALSE
## 1800 rs3977 4 246 1.022160e-01 1.000000e+00 9.268811e-01 FALSE
## 1801 rs12141 15 223 1.022640e-01 1.000000e+00 9.268811e-01 FALSE
## 1802 rs11246 13 588 1.023688e-01 1.000000e+00 9.268811e-01 FALSE
## 1803 rs8641 10 8 1.023743e-01 1.000000e+00 9.268811e-01 FALSE
## 1804 rs10481 12 478 1.023885e-01 1.000000e+00 9.268811e-01 FALSE
## 1805 rs5786 6 233 1.025809e-01 1.000000e+00 9.268811e-01 FALSE
## 1806 rs8238 9 326 1.027634e-01 1.000000e+00 9.268811e-01 FALSE
## 1807 rs15805 21 414 1.027994e-01 1.000000e+00 9.268811e-01 FALSE
## 1808 rs4333 4 602 1.028156e-01 1.000000e+00 9.268811e-01 FALSE
## 1809 rs2224 2 724 1.028790e-01 1.000000e+00 9.268811e-01 FALSE
## 1810 rs1808 2 308 1.029216e-01 1.000000e+00 9.268811e-01 FALSE
## 1811 rs3814 4 83 1.029811e-01 1.000000e+00 9.268811e-01 FALSE
## 1812 rs1167 1 1167 1.031697e-01 1.000000e+00 9.268811e-01 FALSE
## 1813 rs13200 17 79 1.031970e-01 1.000000e+00 9.268811e-01 FALSE
## 1814 rs13988 18 284 1.032273e-01 1.000000e+00 9.268811e-01 FALSE
## 1815 rs11071 13 413 1.032320e-01 1.000000e+00 9.268811e-01 FALSE
## 1816 rs14349 19 73 1.032325e-01 1.000000e+00 9.268811e-01 FALSE
## 1817 rs10418 12 415 1.032619e-01 1.000000e+00 9.268811e-01 FALSE
## 1818 rs11042 13 384 1.033096e-01 1.000000e+00 9.268811e-01 FALSE
## 1819 rs4381 4 650 1.033132e-01 1.000000e+00 9.268811e-01 FALSE
## 1820 rs7944 9 32 1.034681e-01 1.000000e+00 9.268811e-01 FALSE
## 1821 rs11888 14 592 1.035019e-01 1.000000e+00 9.268811e-01 FALSE
## 1822 rs2085 2 585 1.036393e-01 1.000000e+00 9.268811e-01 FALSE
## 1823 rs8322 9 410 1.037711e-01 1.000000e+00 9.268811e-01 FALSE
## 1824 rs10868 13 210 1.038304e-01 1.000000e+00 9.268811e-01 FALSE
## 1825 rs11414 14 118 1.038459e-01 1.000000e+00 9.268811e-01 FALSE
## 1826 rs2722 3 31 1.039219e-01 1.000000e+00 9.268811e-01 FALSE
## 1827 rs7784 8 622 1.039456e-01 1.000000e+00 9.268811e-01 FALSE
## 1828 rs12936 16 410 1.041161e-01 1.000000e+00 9.268811e-01 FALSE
## 1829 rs8892 10 259 1.041287e-01 1.000000e+00 9.268811e-01 FALSE
## 1830 rs3552 3 861 1.042913e-01 1.000000e+00 9.268811e-01 FALSE
## 1831 rs374 1 374 1.044129e-01 1.000000e+00 9.268811e-01 FALSE
## 1832 rs8370 9 458 1.044363e-01 1.000000e+00 9.268811e-01 FALSE
## 1833 rs7497 8 335 1.044536e-01 1.000000e+00 9.268811e-01 FALSE
## 1834 rs6763 7 385 1.045339e-01 1.000000e+00 9.268811e-01 FALSE
## 1835 rs7245 8 83 1.045976e-01 1.000000e+00 9.268811e-01 FALSE
## 1836 rs2813 3 122 1.046998e-01 1.000000e+00 9.268811e-01 FALSE
## 1837 rs9354 11 25 1.047536e-01 1.000000e+00 9.268811e-01 FALSE
## 1838 rs11992 15 74 1.047545e-01 1.000000e+00 9.268811e-01 FALSE
## 1839 rs13937 18 233 1.047959e-01 1.000000e+00 9.268811e-01 FALSE
## 1840 rs8158 9 246 1.049488e-01 1.000000e+00 9.268811e-01 FALSE
## 1841 rs9464 11 135 1.050083e-01 1.000000e+00 9.268811e-01 FALSE
## 1842 rs9149 10 516 1.050129e-01 1.000000e+00 9.268811e-01 FALSE
## 1843 rs4360 4 629 1.050345e-01 1.000000e+00 9.268811e-01 FALSE
## 1844 rs8527 9 615 1.051145e-01 1.000000e+00 9.268811e-01 FALSE
## 1845 rs3466 3 775 1.051624e-01 1.000000e+00 9.268811e-01 FALSE
## 1846 rs5871 6 318 1.052170e-01 1.000000e+00 9.268811e-01 FALSE
## 1847 rs8136 9 224 1.052405e-01 1.000000e+00 9.268811e-01 FALSE
## 1848 rs12213 15 295 1.052714e-01 1.000000e+00 9.268811e-01 FALSE
## 1849 rs1353 1 1353 1.053171e-01 1.000000e+00 9.268811e-01 FALSE
## 1850 rs10687 13 29 1.053477e-01 1.000000e+00 9.268811e-01 FALSE
## 1851 rs12999 16 473 1.054314e-01 1.000000e+00 9.268811e-01 FALSE
## 1852 rs6436 7 58 1.054683e-01 1.000000e+00 9.268811e-01 FALSE
## 1853 rs3713 3 1022 1.055052e-01 1.000000e+00 9.268811e-01 FALSE
## 1854 rs15665 21 274 1.055137e-01 1.000000e+00 9.268811e-01 FALSE
## 1855 rs5226 5 550 1.055153e-01 1.000000e+00 9.268811e-01 FALSE
## 1856 rs15563 21 172 1.056075e-01 1.000000e+00 9.268811e-01 FALSE
## 1857 rs14677 19 401 1.056155e-01 1.000000e+00 9.268811e-01 FALSE
## 1858 rs11937 15 19 1.057167e-01 1.000000e+00 9.268811e-01 FALSE
## 1859 rs3081 3 390 1.057754e-01 1.000000e+00 9.268811e-01 FALSE
## 1860 rs7498 8 336 1.058824e-01 1.000000e+00 9.268811e-01 FALSE
## 1861 rs2546 2 1046 1.059568e-01 1.000000e+00 9.268811e-01 FALSE
## 1862 rs13827 18 123 1.059871e-01 1.000000e+00 9.268811e-01 FALSE
## 1863 rs6815 7 437 1.060582e-01 1.000000e+00 9.268811e-01 FALSE
## 1864 rs9626 11 297 1.060625e-01 1.000000e+00 9.268811e-01 FALSE
## 1865 rs8286 9 374 1.061760e-01 1.000000e+00 9.268811e-01 FALSE
## 1866 rs5540 5 864 1.062478e-01 1.000000e+00 9.268811e-01 FALSE
## 1867 rs617 1 617 1.063096e-01 1.000000e+00 9.268811e-01 FALSE
## 1868 rs10307 12 304 1.063248e-01 1.000000e+00 9.268811e-01 FALSE
## 1869 rs1695 2 195 1.063488e-01 1.000000e+00 9.268811e-01 FALSE
## 1870 rs3306 3 615 1.064811e-01 1.000000e+00 9.268811e-01 FALSE
## 1871 rs12829 16 303 1.067088e-01 1.000000e+00 9.268811e-01 FALSE
## 1872 rs2426 2 926 1.067430e-01 1.000000e+00 9.268811e-01 FALSE
## 1873 rs8824 10 191 1.068550e-01 1.000000e+00 9.268811e-01 FALSE
## 1874 rs15008 20 170 1.069918e-01 1.000000e+00 9.268811e-01 FALSE
## 1875 rs555 1 555 1.069947e-01 1.000000e+00 9.268811e-01 FALSE
## 1876 rs9702 11 373 1.070028e-01 1.000000e+00 9.268811e-01 FALSE
## 1877 rs11331 14 35 1.071460e-01 1.000000e+00 9.268811e-01 FALSE
## 1878 rs3126 3 435 1.072508e-01 1.000000e+00 9.268811e-01 FALSE
## 1879 rs9850 11 521 1.072915e-01 1.000000e+00 9.268811e-01 FALSE
## 1880 rs12721 16 195 1.073198e-01 1.000000e+00 9.268811e-01 FALSE
## 1881 rs6825 7 447 1.073229e-01 1.000000e+00 9.268811e-01 FALSE
## 1882 rs6570 7 192 1.073237e-01 1.000000e+00 9.268811e-01 FALSE
## 1883 rs9479 11 150 1.074050e-01 1.000000e+00 9.268811e-01 FALSE
## 1884 rs12096 15 178 1.075588e-01 1.000000e+00 9.268811e-01 FALSE
## 1885 rs14931 20 93 1.076468e-01 1.000000e+00 9.268811e-01 FALSE
## 1886 rs2714 3 23 1.077256e-01 1.000000e+00 9.268811e-01 FALSE
## 1887 rs311 1 311 1.078113e-01 1.000000e+00 9.268811e-01 FALSE
## 1888 rs1889 2 389 1.078961e-01 1.000000e+00 9.268811e-01 FALSE
## 1889 rs12507 15 589 1.079199e-01 1.000000e+00 9.268811e-01 FALSE
## 1890 rs406 1 406 1.079871e-01 1.000000e+00 9.268811e-01 FALSE
## 1891 rs10155 12 152 1.080363e-01 1.000000e+00 9.268811e-01 FALSE
## 1892 rs637 1 637 1.080966e-01 1.000000e+00 9.268811e-01 FALSE
## 1893 rs3363 3 672 1.081015e-01 1.000000e+00 9.268811e-01 FALSE
## 1894 rs1116 1 1116 1.082035e-01 1.000000e+00 9.268811e-01 FALSE
## 1895 rs6288 6 735 1.082515e-01 1.000000e+00 9.268811e-01 FALSE
## 1896 rs4985 5 309 1.082788e-01 1.000000e+00 9.268811e-01 FALSE
## 1897 rs9788 11 459 1.083121e-01 1.000000e+00 9.268811e-01 FALSE
## 1898 rs378 1 378 1.084887e-01 1.000000e+00 9.268811e-01 FALSE
## 1899 rs3018 3 327 1.084893e-01 1.000000e+00 9.268811e-01 FALSE
## 1900 rs10695 13 37 1.085030e-01 1.000000e+00 9.268811e-01 FALSE
## 1901 rs7920 9 8 1.085235e-01 1.000000e+00 9.268811e-01 FALSE
## 1902 rs15747 21 356 1.086753e-01 1.000000e+00 9.268811e-01 FALSE
## 1903 rs1565 2 65 1.087422e-01 1.000000e+00 9.268811e-01 FALSE
## 1904 rs8160 9 248 1.087426e-01 1.000000e+00 9.268811e-01 FALSE
## 1905 rs1150 1 1150 1.087546e-01 1.000000e+00 9.268811e-01 FALSE
## 1906 rs1357 1 1357 1.088232e-01 1.000000e+00 9.268811e-01 FALSE
## 1907 rs6395 7 17 1.088740e-01 1.000000e+00 9.268811e-01 FALSE
## 1908 rs5399 5 723 1.089021e-01 1.000000e+00 9.268811e-01 FALSE
## 1909 rs2490 2 990 1.090134e-01 1.000000e+00 9.268811e-01 FALSE
## 1910 rs6020 6 467 1.091118e-01 1.000000e+00 9.268811e-01 FALSE
## 1911 rs6898 7 520 1.092695e-01 1.000000e+00 9.268811e-01 FALSE
## 1912 rs12392 15 474 1.094246e-01 1.000000e+00 9.268811e-01 FALSE
## 1913 rs13904 18 200 1.095926e-01 1.000000e+00 9.268811e-01 FALSE
## 1914 rs15589 21 198 1.096024e-01 1.000000e+00 9.268811e-01 FALSE
## 1915 rs3582 3 891 1.097438e-01 1.000000e+00 9.268811e-01 FALSE
## 1916 rs5575 6 22 1.097718e-01 1.000000e+00 9.268811e-01 FALSE
## 1917 rs1691 2 191 1.097832e-01 1.000000e+00 9.268811e-01 FALSE
## 1918 rs2033 2 533 1.098150e-01 1.000000e+00 9.268811e-01 FALSE
## 1919 rs7813 8 651 1.098501e-01 1.000000e+00 9.268811e-01 FALSE
## 1920 rs10055 12 52 1.098504e-01 1.000000e+00 9.268811e-01 FALSE
## 1921 rs8710 10 77 1.099326e-01 1.000000e+00 9.268811e-01 FALSE
## 1922 rs9614 11 285 1.099713e-01 1.000000e+00 9.268811e-01 FALSE
## 1923 rs2395 2 895 1.099856e-01 1.000000e+00 9.268811e-01 FALSE
## 1924 rs8355 9 443 1.099933e-01 1.000000e+00 9.268811e-01 FALSE
## 1925 rs14292 19 16 1.100308e-01 1.000000e+00 9.268811e-01 FALSE
## 1926 rs10515 12 512 1.100469e-01 1.000000e+00 9.268811e-01 FALSE
## 1927 rs14923 20 85 1.101410e-01 1.000000e+00 9.268811e-01 FALSE
## 1928 rs6699 7 321 1.101780e-01 1.000000e+00 9.268811e-01 FALSE
## 1929 rs4567 4 836 1.101852e-01 1.000000e+00 9.268811e-01 FALSE
## 1930 rs13485 17 364 1.102088e-01 1.000000e+00 9.268811e-01 FALSE
## 1931 rs4930 5 254 1.102136e-01 1.000000e+00 9.268811e-01 FALSE
## 1932 rs13198 17 77 1.102837e-01 1.000000e+00 9.268811e-01 FALSE
## 1933 rs9967 11 638 1.102978e-01 1.000000e+00 9.268811e-01 FALSE
## 1934 rs257 1 257 1.103351e-01 1.000000e+00 9.268811e-01 FALSE
## 1935 rs3160 3 469 1.103533e-01 1.000000e+00 9.268811e-01 FALSE
## 1936 rs7590 8 428 1.104071e-01 1.000000e+00 9.268811e-01 FALSE
## 1937 rs13739 18 35 1.104697e-01 1.000000e+00 9.268811e-01 FALSE
## 1938 rs4081 4 350 1.105525e-01 1.000000e+00 9.268811e-01 FALSE
## 1939 rs9402 11 73 1.105865e-01 1.000000e+00 9.268811e-01 FALSE
## 1940 rs10366 12 363 1.106879e-01 1.000000e+00 9.268811e-01 FALSE
## 1941 rs13185 17 64 1.108833e-01 1.000000e+00 9.268811e-01 FALSE
## 1942 rs13387 17 266 1.109008e-01 1.000000e+00 9.268811e-01 FALSE
## 1943 rs14754 19 478 1.109319e-01 1.000000e+00 9.268811e-01 FALSE
## 1944 rs5376 5 700 1.109402e-01 1.000000e+00 9.268811e-01 FALSE
## 1945 rs3601 3 910 1.109799e-01 1.000000e+00 9.268811e-01 FALSE
## 1946 rs11449 14 153 1.109842e-01 1.000000e+00 9.268811e-01 FALSE
## 1947 rs1017 1 1017 1.110784e-01 1.000000e+00 9.268811e-01 FALSE
## 1948 rs14320 19 44 1.114089e-01 1.000000e+00 9.268811e-01 FALSE
## 1949 rs5107 5 431 1.114123e-01 1.000000e+00 9.268811e-01 FALSE
## 1950 rs8434 9 522 1.114343e-01 1.000000e+00 9.268811e-01 FALSE
## 1951 rs4222 4 491 1.115399e-01 1.000000e+00 9.268811e-01 FALSE
## 1952 rs12526 15 608 1.115449e-01 1.000000e+00 9.268811e-01 FALSE
## 1953 rs10429 12 426 1.116108e-01 1.000000e+00 9.268811e-01 FALSE
## 1954 rs12214 15 296 1.116587e-01 1.000000e+00 9.268811e-01 FALSE
## 1955 rs1347 1 1347 1.116691e-01 1.000000e+00 9.268811e-01 FALSE
## 1956 rs6382 7 4 1.117627e-01 1.000000e+00 9.268811e-01 FALSE
## 1957 rs14887 20 49 1.119273e-01 1.000000e+00 9.268811e-01 FALSE
## 1958 rs10683 13 25 1.121104e-01 1.000000e+00 9.268811e-01 FALSE
## 1959 rs12327 15 409 1.121213e-01 1.000000e+00 9.268811e-01 FALSE
## 1960 rs10962 13 304 1.122209e-01 1.000000e+00 9.268811e-01 FALSE
## 1961 rs9558 11 229 1.122449e-01 1.000000e+00 9.268811e-01 FALSE
## 1962 rs9003 10 370 1.123009e-01 1.000000e+00 9.268811e-01 FALSE
## 1963 rs198 1 198 1.123082e-01 1.000000e+00 9.268811e-01 FALSE
## 1964 rs10654 12 651 1.123137e-01 1.000000e+00 9.268811e-01 FALSE
## 1965 rs7904 8 742 1.123404e-01 1.000000e+00 9.268811e-01 FALSE
## 1966 rs7954 9 42 1.125624e-01 1.000000e+00 9.268811e-01 FALSE
## 1967 rs1383 1 1383 1.125846e-01 1.000000e+00 9.268811e-01 FALSE
## 1968 rs7234 8 72 1.126932e-01 1.000000e+00 9.268811e-01 FALSE
## 1969 rs16121 22 186 1.127043e-01 1.000000e+00 9.268811e-01 FALSE
## 1970 rs9252 10 619 1.127617e-01 1.000000e+00 9.268811e-01 FALSE
## 1971 rs12647 16 121 1.128489e-01 1.000000e+00 9.268811e-01 FALSE
## 1972 rs3577 3 886 1.129482e-01 1.000000e+00 9.268811e-01 FALSE
## 1973 rs15249 20 411 1.130374e-01 1.000000e+00 9.268811e-01 FALSE
## 1974 rs3235 3 544 1.130381e-01 1.000000e+00 9.268811e-01 FALSE
## 1975 rs16362 22 427 1.130414e-01 1.000000e+00 9.268811e-01 FALSE
## 1976 rs2999 3 308 1.130610e-01 1.000000e+00 9.268811e-01 FALSE
## 1977 rs1198 1 1198 1.131138e-01 1.000000e+00 9.268811e-01 FALSE
## 1978 rs5204 5 528 1.131491e-01 1.000000e+00 9.268811e-01 FALSE
## 1979 rs1413 1 1413 1.131700e-01 1.000000e+00 9.268811e-01 FALSE
## 1980 rs2226 2 726 1.131869e-01 1.000000e+00 9.268811e-01 FALSE
## 1981 rs11573 14 277 1.131889e-01 1.000000e+00 9.268811e-01 FALSE
## 1982 rs7388 8 226 1.131936e-01 1.000000e+00 9.268811e-01 FALSE
## 1983 rs6694 7 316 1.132188e-01 1.000000e+00 9.268811e-01 FALSE
## 1984 rs16135 22 200 1.132705e-01 1.000000e+00 9.268811e-01 FALSE
## 1985 rs4958 5 282 1.132885e-01 1.000000e+00 9.268811e-01 FALSE
## 1986 rs2392 2 892 1.133133e-01 1.000000e+00 9.268811e-01 FALSE
## 1987 rs6241 6 688 1.133740e-01 1.000000e+00 9.268811e-01 FALSE
## 1988 rs14174 18 470 1.134609e-01 1.000000e+00 9.268811e-01 FALSE
## 1989 rs6392 7 14 1.135035e-01 1.000000e+00 9.268811e-01 FALSE
## 1990 rs11950 15 32 1.135474e-01 1.000000e+00 9.268811e-01 FALSE
## 1991 rs1595 2 95 1.136762e-01 1.000000e+00 9.268811e-01 FALSE
## 1992 rs5683 6 130 1.136880e-01 1.000000e+00 9.268811e-01 FALSE
## 1993 rs10150 12 147 1.136964e-01 1.000000e+00 9.268811e-01 FALSE
## 1994 rs138 1 138 1.137186e-01 1.000000e+00 9.268811e-01 FALSE
## 1995 rs1053 1 1053 1.138049e-01 1.000000e+00 9.268811e-01 FALSE
## 1996 rs13604 17 483 1.138206e-01 1.000000e+00 9.268811e-01 FALSE
## 1997 rs15633 21 242 1.138243e-01 1.000000e+00 9.268811e-01 FALSE
## 1998 rs15560 21 169 1.139462e-01 1.000000e+00 9.268811e-01 FALSE
## 1999 rs4073 4 342 1.139750e-01 1.000000e+00 9.268811e-01 FALSE
## 2000 rs14158 18 454 1.139755e-01 1.000000e+00 9.268811e-01 FALSE
## 2001 rs5333 5 657 1.142687e-01 1.000000e+00 9.268811e-01 FALSE
## 2002 rs15398 21 7 1.142788e-01 1.000000e+00 9.268811e-01 FALSE
## 2003 rs15973 22 38 1.142855e-01 1.000000e+00 9.268811e-01 FALSE
## 2004 rs14830 19 554 1.143462e-01 1.000000e+00 9.268811e-01 FALSE
## 2005 rs6244 6 691 1.143703e-01 1.000000e+00 9.268811e-01 FALSE
## 2006 rs6264 6 711 1.145425e-01 1.000000e+00 9.268811e-01 FALSE
## 2007 rs8755 10 122 1.145797e-01 1.000000e+00 9.268811e-01 FALSE
## 2008 rs1880 2 380 1.146637e-01 1.000000e+00 9.268811e-01 FALSE
## 2009 rs4770 5 94 1.147012e-01 1.000000e+00 9.268811e-01 FALSE
## 2010 rs7219 8 57 1.147221e-01 1.000000e+00 9.268811e-01 FALSE
## 2011 rs14697 19 421 1.147272e-01 1.000000e+00 9.268811e-01 FALSE
## 2012 rs465 1 465 1.147627e-01 1.000000e+00 9.268811e-01 FALSE
## 2013 rs13209 17 88 1.147758e-01 1.000000e+00 9.268811e-01 FALSE
## 2014 rs13440 17 319 1.147876e-01 1.000000e+00 9.268811e-01 FALSE
## 2015 rs421 1 421 1.148325e-01 1.000000e+00 9.268811e-01 FALSE
## 2016 rs15417 21 26 1.148838e-01 1.000000e+00 9.268811e-01 FALSE
## 2017 rs10296 12 293 1.149476e-01 1.000000e+00 9.268811e-01 FALSE
## 2018 rs1567 2 67 1.150771e-01 1.000000e+00 9.268811e-01 FALSE
## 2019 rs10715 13 57 1.152949e-01 1.000000e+00 9.268811e-01 FALSE
## 2020 rs505 1 505 1.153620e-01 1.000000e+00 9.268811e-01 FALSE
## 2021 rs5822 6 269 1.153947e-01 1.000000e+00 9.268811e-01 FALSE
## 2022 rs6261 6 708 1.154001e-01 1.000000e+00 9.268811e-01 FALSE
## 2023 rs3098 3 407 1.154525e-01 1.000000e+00 9.268811e-01 FALSE
## 2024 rs1944 2 444 1.155660e-01 1.000000e+00 9.268811e-01 FALSE
## 2025 rs1464 1 1464 1.155733e-01 1.000000e+00 9.268811e-01 FALSE
## 2026 rs10766 13 108 1.156076e-01 1.000000e+00 9.268811e-01 FALSE
## 2027 rs1514 2 14 1.156531e-01 1.000000e+00 9.268811e-01 FALSE
## 2028 rs12529 16 3 1.156745e-01 1.000000e+00 9.268811e-01 FALSE
## 2029 rs14927 20 89 1.156918e-01 1.000000e+00 9.268811e-01 FALSE
## 2030 rs15248 20 410 1.157046e-01 1.000000e+00 9.268811e-01 FALSE
## 2031 rs642 1 642 1.158171e-01 1.000000e+00 9.268811e-01 FALSE
## 2032 rs10811 13 153 1.158174e-01 1.000000e+00 9.268811e-01 FALSE
## 2033 rs6332 6 779 1.159835e-01 1.000000e+00 9.268811e-01 FALSE
## 2034 rs7707 8 545 1.159866e-01 1.000000e+00 9.268811e-01 FALSE
## 2035 rs10152 12 149 1.160584e-01 1.000000e+00 9.268811e-01 FALSE
## 2036 rs9370 11 41 1.160836e-01 1.000000e+00 9.268811e-01 FALSE
## 2037 rs3891 4 160 1.161208e-01 1.000000e+00 9.268811e-01 FALSE
## 2038 rs14786 19 510 1.161563e-01 1.000000e+00 9.268811e-01 FALSE
## 2039 rs169 1 169 1.161747e-01 1.000000e+00 9.268811e-01 FALSE
## 2040 rs5062 5 386 1.162081e-01 1.000000e+00 9.268811e-01 FALSE
## 2041 rs13568 17 447 1.162088e-01 1.000000e+00 9.268811e-01 FALSE
## 2042 rs3534 3 843 1.162245e-01 1.000000e+00 9.268811e-01 FALSE
## 2043 rs15203 20 365 1.162582e-01 1.000000e+00 9.268811e-01 FALSE
## 2044 rs9324 10 691 1.162968e-01 1.000000e+00 9.268811e-01 FALSE
## 2045 rs12497 15 579 1.163987e-01 1.000000e+00 9.268811e-01 FALSE
## 2046 rs14658 19 382 1.164414e-01 1.000000e+00 9.268811e-01 FALSE
## 2047 rs15852 21 461 1.165597e-01 1.000000e+00 9.268811e-01 FALSE
## 2048 rs13901 18 197 1.165639e-01 1.000000e+00 9.268811e-01 FALSE
## 2049 rs16364 22 429 1.167478e-01 1.000000e+00 9.268811e-01 FALSE
## 2050 rs10867 13 209 1.168035e-01 1.000000e+00 9.268811e-01 FALSE
## 2051 rs4771 5 95 1.168725e-01 1.000000e+00 9.268811e-01 FALSE
## 2052 rs10540 12 537 1.169627e-01 1.000000e+00 9.268811e-01 FALSE
## 2053 rs7471 8 309 1.171221e-01 1.000000e+00 9.268811e-01 FALSE
## 2054 rs16141 22 206 1.171535e-01 1.000000e+00 9.268811e-01 FALSE
## 2055 rs995 1 995 1.171573e-01 1.000000e+00 9.268811e-01 FALSE
## 2056 rs15664 21 273 1.172807e-01 1.000000e+00 9.268811e-01 FALSE
## 2057 rs12402 15 484 1.173800e-01 1.000000e+00 9.268811e-01 FALSE
## 2058 rs8461 9 549 1.174172e-01 1.000000e+00 9.268811e-01 FALSE
## 2059 rs18 1 18 1.174874e-01 1.000000e+00 9.268811e-01 FALSE
## 2060 rs16009 22 74 1.174914e-01 1.000000e+00 9.268811e-01 FALSE
## 2061 rs1684 2 184 1.175557e-01 1.000000e+00 9.268811e-01 FALSE
## 2062 rs12301 15 383 1.175671e-01 1.000000e+00 9.268811e-01 FALSE
## 2063 rs6066 6 513 1.176811e-01 1.000000e+00 9.268811e-01 FALSE
## 2064 rs910 1 910 1.177044e-01 1.000000e+00 9.268811e-01 FALSE
## 2065 rs2688 2 1188 1.177062e-01 1.000000e+00 9.268811e-01 FALSE
## 2066 rs13835 18 131 1.178335e-01 1.000000e+00 9.268811e-01 FALSE
## 2067 rs2601 2 1101 1.179006e-01 1.000000e+00 9.268811e-01 FALSE
## 2068 rs8145 9 233 1.180027e-01 1.000000e+00 9.268811e-01 FALSE
## 2069 rs15372 20 534 1.180516e-01 1.000000e+00 9.268811e-01 FALSE
## 2070 rs4387 4 656 1.181401e-01 1.000000e+00 9.268811e-01 FALSE
## 2071 rs2892 3 201 1.181561e-01 1.000000e+00 9.268811e-01 FALSE
## 2072 rs14953 20 115 1.181812e-01 1.000000e+00 9.268811e-01 FALSE
## 2073 rs6188 6 635 1.182303e-01 1.000000e+00 9.268811e-01 FALSE
## 2074 rs14906 20 68 1.182744e-01 1.000000e+00 9.268811e-01 FALSE
## 2075 rs11598 14 302 1.182993e-01 1.000000e+00 9.268811e-01 FALSE
## 2076 rs5265 5 589 1.185182e-01 1.000000e+00 9.268811e-01 FALSE
## 2077 rs8115 9 203 1.185492e-01 1.000000e+00 9.268811e-01 FALSE
## 2078 rs3015 3 324 1.185709e-01 1.000000e+00 9.268811e-01 FALSE
## 2079 rs16088 22 153 1.185887e-01 1.000000e+00 9.268811e-01 FALSE
## 2080 rs15149 20 311 1.186215e-01 1.000000e+00 9.268811e-01 FALSE
## 2081 rs13948 18 244 1.186520e-01 1.000000e+00 9.268811e-01 FALSE
## 2082 rs877 1 877 1.186722e-01 1.000000e+00 9.268811e-01 FALSE
## 2083 rs8908 10 275 1.187320e-01 1.000000e+00 9.268811e-01 FALSE
## 2084 rs10509 12 506 1.188074e-01 1.000000e+00 9.268811e-01 FALSE
## 2085 rs11367 14 71 1.188078e-01 1.000000e+00 9.268811e-01 FALSE
## 2086 rs14227 18 523 1.188198e-01 1.000000e+00 9.268811e-01 FALSE
## 2087 rs5267 5 591 1.188652e-01 1.000000e+00 9.268811e-01 FALSE
## 2088 rs2790 3 99 1.188976e-01 1.000000e+00 9.268811e-01 FALSE
## 2089 rs4273 4 542 1.189830e-01 1.000000e+00 9.268811e-01 FALSE
## 2090 rs1637 2 137 1.190192e-01 1.000000e+00 9.268811e-01 FALSE
## 2091 rs10166 12 163 1.190303e-01 1.000000e+00 9.268811e-01 FALSE
## 2092 rs13662 17 541 1.191249e-01 1.000000e+00 9.268811e-01 FALSE
## 2093 rs2218 2 718 1.192684e-01 1.000000e+00 9.268811e-01 FALSE
## 2094 rs3995 4 264 1.193427e-01 1.000000e+00 9.268811e-01 FALSE
## 2095 rs7670 8 508 1.194469e-01 1.000000e+00 9.268811e-01 FALSE
## 2096 rs9331 11 2 1.196110e-01 1.000000e+00 9.268811e-01 FALSE
## 2097 rs2798 3 107 1.196622e-01 1.000000e+00 9.268811e-01 FALSE
## 2098 rs8920 10 287 1.196718e-01 1.000000e+00 9.268811e-01 FALSE
## 2099 rs15075 20 237 1.197361e-01 1.000000e+00 9.268811e-01 FALSE
## 2100 rs5806 6 253 1.198098e-01 1.000000e+00 9.268811e-01 FALSE
## 2101 rs5089 5 413 1.198176e-01 1.000000e+00 9.268811e-01 FALSE
## 2102 rs2777 3 86 1.198422e-01 1.000000e+00 9.268811e-01 FALSE
## 2103 rs8773 10 140 1.198742e-01 1.000000e+00 9.268811e-01 FALSE
## 2104 rs14476 19 200 1.199832e-01 1.000000e+00 9.268811e-01 FALSE
## 2105 rs9144 10 511 1.200006e-01 1.000000e+00 9.268811e-01 FALSE
## 2106 rs1574 2 74 1.201062e-01 1.000000e+00 9.268811e-01 FALSE
## 2107 rs16429 22 494 1.201648e-01 1.000000e+00 9.268811e-01 FALSE
## 2108 rs8068 9 156 1.201760e-01 1.000000e+00 9.268811e-01 FALSE
## 2109 rs11667 14 371 1.202115e-01 1.000000e+00 9.268811e-01 FALSE
## 2110 rs11804 14 508 1.204318e-01 1.000000e+00 9.268811e-01 FALSE
## 2111 rs13456 17 335 1.204621e-01 1.000000e+00 9.268811e-01 FALSE
## 2112 rs7075 7 697 1.206460e-01 1.000000e+00 9.268811e-01 FALSE
## 2113 rs13667 17 546 1.206468e-01 1.000000e+00 9.268811e-01 FALSE
## 2114 rs2040 2 540 1.207364e-01 1.000000e+00 9.268811e-01 FALSE
## 2115 rs4780 5 104 1.207447e-01 1.000000e+00 9.268811e-01 FALSE
## 2116 rs15839 21 448 1.207578e-01 1.000000e+00 9.268811e-01 FALSE
## 2117 rs8561 9 649 1.207932e-01 1.000000e+00 9.268811e-01 FALSE
## 2118 rs11894 14 598 1.208301e-01 1.000000e+00 9.268811e-01 FALSE
## 2119 rs4649 4 918 1.209089e-01 1.000000e+00 9.268811e-01 FALSE
## 2120 rs9013 10 380 1.209215e-01 1.000000e+00 9.268811e-01 FALSE
## 2121 rs11722 14 426 1.209684e-01 1.000000e+00 9.268811e-01 FALSE
## 2122 rs15641 21 250 1.210654e-01 1.000000e+00 9.268811e-01 FALSE
## 2123 rs13708 18 4 1.210848e-01 1.000000e+00 9.268811e-01 FALSE
## 2124 rs5317 5 641 1.211238e-01 1.000000e+00 9.268811e-01 FALSE
## 2125 rs6749 7 371 1.211742e-01 1.000000e+00 9.268811e-01 FALSE
## 2126 rs5638 6 85 1.211854e-01 1.000000e+00 9.268811e-01 FALSE
## 2127 rs10948 13 290 1.212255e-01 1.000000e+00 9.268811e-01 FALSE
## 2128 rs1439 1 1439 1.213782e-01 1.000000e+00 9.268811e-01 FALSE
## 2129 rs1485 1 1485 1.213830e-01 1.000000e+00 9.268811e-01 FALSE
## 2130 rs1905 2 405 1.214366e-01 1.000000e+00 9.268811e-01 FALSE
## 2131 rs3708 3 1017 1.214551e-01 1.000000e+00 9.268811e-01 FALSE
## 2132 rs8201 9 289 1.215788e-01 1.000000e+00 9.268811e-01 FALSE
## 2133 rs2509 2 1009 1.217388e-01 1.000000e+00 9.268811e-01 FALSE
## 2134 rs11469 14 173 1.219264e-01 1.000000e+00 9.268811e-01 FALSE
## 2135 rs8850 10 217 1.219396e-01 1.000000e+00 9.268811e-01 FALSE
## 2136 rs10382 12 379 1.220008e-01 1.000000e+00 9.268811e-01 FALSE
## 2137 rs12767 16 241 1.220073e-01 1.000000e+00 9.268811e-01 FALSE
## 2138 rs15543 21 152 1.220285e-01 1.000000e+00 9.268811e-01 FALSE
## 2139 rs14097 18 393 1.221364e-01 1.000000e+00 9.268811e-01 FALSE
## 2140 rs14364 19 88 1.221611e-01 1.000000e+00 9.268811e-01 FALSE
## 2141 rs9478 11 149 1.223148e-01 1.000000e+00 9.268811e-01 FALSE
## 2142 rs9320 10 687 1.223175e-01 1.000000e+00 9.268811e-01 FALSE
## 2143 rs2882 3 191 1.223779e-01 1.000000e+00 9.268811e-01 FALSE
## 2144 rs5438 5 762 1.224844e-01 1.000000e+00 9.268811e-01 FALSE
## 2145 rs16434 22 499 1.225087e-01 1.000000e+00 9.268811e-01 FALSE
## 2146 rs9899 11 570 1.226002e-01 1.000000e+00 9.268811e-01 FALSE
## 2147 rs15999 22 64 1.226701e-01 1.000000e+00 9.268811e-01 FALSE
## 2148 rs15904 21 513 1.227591e-01 1.000000e+00 9.268811e-01 FALSE
## 2149 rs15103 20 265 1.228073e-01 1.000000e+00 9.268811e-01 FALSE
## 2150 rs12658 16 132 1.228088e-01 1.000000e+00 9.268811e-01 FALSE
## 2151 rs5657 6 104 1.228230e-01 1.000000e+00 9.268811e-01 FALSE
## 2152 rs13884 18 180 1.229193e-01 1.000000e+00 9.268811e-01 FALSE
## 2153 rs692 1 692 1.229467e-01 1.000000e+00 9.268811e-01 FALSE
## 2154 rs12075 15 157 1.230301e-01 1.000000e+00 9.268811e-01 FALSE
## 2155 rs1182 1 1182 1.230356e-01 1.000000e+00 9.268811e-01 FALSE
## 2156 rs5550 5 874 1.230515e-01 1.000000e+00 9.268811e-01 FALSE
## 2157 rs4473 4 742 1.231338e-01 1.000000e+00 9.268811e-01 FALSE
## 2158 rs12917 16 391 1.231416e-01 1.000000e+00 9.268811e-01 FALSE
## 2159 rs10441 12 438 1.231477e-01 1.000000e+00 9.268811e-01 FALSE
## 2160 rs15268 20 430 1.232507e-01 1.000000e+00 9.268811e-01 FALSE
## 2161 rs11853 14 557 1.232940e-01 1.000000e+00 9.268811e-01 FALSE
## 2162 rs262 1 262 1.233006e-01 1.000000e+00 9.268811e-01 FALSE
## 2163 rs4376 4 645 1.234351e-01 1.000000e+00 9.268811e-01 FALSE
## 2164 rs13493 17 372 1.235304e-01 1.000000e+00 9.268811e-01 FALSE
## 2165 rs7439 8 277 1.235590e-01 1.000000e+00 9.268811e-01 FALSE
## 2166 rs11489 14 193 1.236918e-01 1.000000e+00 9.268811e-01 FALSE
## 2167 rs9377 11 48 1.237133e-01 1.000000e+00 9.268811e-01 FALSE
## 2168 rs8699 10 66 1.238560e-01 1.000000e+00 9.268811e-01 FALSE
## 2169 rs8473 9 561 1.238561e-01 1.000000e+00 9.268811e-01 FALSE
## 2170 rs9289 10 656 1.238877e-01 1.000000e+00 9.268811e-01 FALSE
## 2171 rs3628 3 937 1.239724e-01 1.000000e+00 9.268811e-01 FALSE
## 2172 rs12698 16 172 1.240418e-01 1.000000e+00 9.268811e-01 FALSE
## 2173 rs4848 5 172 1.240782e-01 1.000000e+00 9.268811e-01 FALSE
## 2174 rs12080 15 162 1.241557e-01 1.000000e+00 9.268811e-01 FALSE
## 2175 rs14773 19 497 1.242028e-01 1.000000e+00 9.268811e-01 FALSE
## 2176 rs5887 6 334 1.242410e-01 1.000000e+00 9.268811e-01 FALSE
## 2177 rs11749 14 453 1.244471e-01 1.000000e+00 9.268811e-01 FALSE
## 2178 rs12533 16 7 1.244919e-01 1.000000e+00 9.268811e-01 FALSE
## 2179 rs6866 7 488 1.245171e-01 1.000000e+00 9.268811e-01 FALSE
## 2180 rs2816 3 125 1.245369e-01 1.000000e+00 9.268811e-01 FALSE
## 2181 rs14739 19 463 1.245568e-01 1.000000e+00 9.268811e-01 FALSE
## 2182 rs7124 7 746 1.245769e-01 1.000000e+00 9.268811e-01 FALSE
## 2183 rs1907 2 407 1.246014e-01 1.000000e+00 9.268811e-01 FALSE
## 2184 rs688 1 688 1.246969e-01 1.000000e+00 9.268811e-01 FALSE
## 2185 rs2012 2 512 1.247945e-01 1.000000e+00 9.268811e-01 FALSE
## 2186 rs411 1 411 1.248958e-01 1.000000e+00 9.268811e-01 FALSE
## 2187 rs12156 15 238 1.249457e-01 1.000000e+00 9.268811e-01 FALSE
## 2188 rs1798 2 298 1.250383e-01 1.000000e+00 9.268811e-01 FALSE
## 2189 rs15492 21 101 1.250448e-01 1.000000e+00 9.268811e-01 FALSE
## 2190 rs9747 11 418 1.251126e-01 1.000000e+00 9.268811e-01 FALSE
## 2191 rs980 1 980 1.251486e-01 1.000000e+00 9.268811e-01 FALSE
## 2192 rs6467 7 89 1.251646e-01 1.000000e+00 9.268811e-01 FALSE
## 2193 rs13086 16 560 1.251868e-01 1.000000e+00 9.268811e-01 FALSE
## 2194 rs9984 11 655 1.251928e-01 1.000000e+00 9.268811e-01 FALSE
## 2195 rs12913 16 387 1.252409e-01 1.000000e+00 9.268811e-01 FALSE
## 2196 rs13195 17 74 1.253353e-01 1.000000e+00 9.268811e-01 FALSE
## 2197 rs6007 6 454 1.253459e-01 1.000000e+00 9.268811e-01 FALSE
## 2198 rs924 1 924 1.254435e-01 1.000000e+00 9.268811e-01 FALSE
## 2199 rs4726 5 50 1.254533e-01 1.000000e+00 9.268811e-01 FALSE
## 2200 rs7190 8 28 1.255557e-01 1.000000e+00 9.268811e-01 FALSE
## 2201 rs4303 4 572 1.255872e-01 1.000000e+00 9.268811e-01 FALSE
## 2202 rs9574 11 245 1.257137e-01 1.000000e+00 9.268811e-01 FALSE
## 2203 rs9554 11 225 1.257974e-01 1.000000e+00 9.268811e-01 FALSE
## 2204 rs13445 17 324 1.258785e-01 1.000000e+00 9.268811e-01 FALSE
## 2205 rs3198 3 507 1.258861e-01 1.000000e+00 9.268811e-01 FALSE
## 2206 rs14301 19 25 1.259174e-01 1.000000e+00 9.268811e-01 FALSE
## 2207 rs988 1 988 1.259528e-01 1.000000e+00 9.268811e-01 FALSE
## 2208 rs7449 8 287 1.259902e-01 1.000000e+00 9.268811e-01 FALSE
## 2209 rs5753 6 200 1.260773e-01 1.000000e+00 9.268811e-01 FALSE
## 2210 rs10668 13 10 1.260784e-01 1.000000e+00 9.268811e-01 FALSE
## 2211 rs2784 3 93 1.261267e-01 1.000000e+00 9.268811e-01 FALSE
## 2212 rs14567 19 291 1.262192e-01 1.000000e+00 9.268811e-01 FALSE
## 2213 rs3774 4 43 1.262336e-01 1.000000e+00 9.268811e-01 FALSE
## 2214 rs11580 14 284 1.264521e-01 1.000000e+00 9.268811e-01 FALSE
## 2215 rs13526 17 405 1.266815e-01 1.000000e+00 9.268811e-01 FALSE
## 2216 rs6686 7 308 1.266910e-01 1.000000e+00 9.268811e-01 FALSE
## 2217 rs10122 12 119 1.269127e-01 1.000000e+00 9.268811e-01 FALSE
## 2218 rs2231 2 731 1.269210e-01 1.000000e+00 9.268811e-01 FALSE
## 2219 rs14509 19 233 1.269709e-01 1.000000e+00 9.268811e-01 FALSE
## 2220 rs6741 7 363 1.269994e-01 1.000000e+00 9.268811e-01 FALSE
## 2221 rs524 1 524 1.270028e-01 1.000000e+00 9.268811e-01 FALSE
## 2222 rs5729 6 176 1.270668e-01 1.000000e+00 9.268811e-01 FALSE
## 2223 rs16031 22 96 1.272143e-01 1.000000e+00 9.268811e-01 FALSE
## 2224 rs5670 6 117 1.273734e-01 1.000000e+00 9.268811e-01 FALSE
## 2225 rs10627 12 624 1.273737e-01 1.000000e+00 9.268811e-01 FALSE
## 2226 rs15612 21 221 1.274380e-01 1.000000e+00 9.268811e-01 FALSE
## 2227 rs786 1 786 1.274839e-01 1.000000e+00 9.268811e-01 FALSE
## 2228 rs4143 4 412 1.274982e-01 1.000000e+00 9.268811e-01 FALSE
## 2229 rs11726 14 430 1.277835e-01 1.000000e+00 9.268811e-01 FALSE
## 2230 rs10027 12 24 1.278540e-01 1.000000e+00 9.268811e-01 FALSE
## 2231 rs6845 7 467 1.278747e-01 1.000000e+00 9.268811e-01 FALSE
## 2232 rs13055 16 529 1.280071e-01 1.000000e+00 9.268811e-01 FALSE
## 2233 rs2674 2 1174 1.280302e-01 1.000000e+00 9.268811e-01 FALSE
## 2234 rs7437 8 275 1.281127e-01 1.000000e+00 9.268811e-01 FALSE
## 2235 rs14080 18 376 1.281850e-01 1.000000e+00 9.268811e-01 FALSE
## 2236 rs5697 6 144 1.283016e-01 1.000000e+00 9.268811e-01 FALSE
## 2237 rs7489 8 327 1.283202e-01 1.000000e+00 9.268811e-01 FALSE
## 2238 rs2531 2 1031 1.283271e-01 1.000000e+00 9.268811e-01 FALSE
## 2239 rs12996 16 470 1.283519e-01 1.000000e+00 9.268811e-01 FALSE
## 2240 rs14520 19 244 1.284349e-01 1.000000e+00 9.268811e-01 FALSE
## 2241 rs8739 10 106 1.284886e-01 1.000000e+00 9.268811e-01 FALSE
## 2242 rs12056 15 138 1.285258e-01 1.000000e+00 9.268811e-01 FALSE
## 2243 rs3543 3 852 1.285360e-01 1.000000e+00 9.268811e-01 FALSE
## 2244 rs2618 2 1118 1.285549e-01 1.000000e+00 9.268811e-01 FALSE
## 2245 rs6061 6 508 1.287007e-01 1.000000e+00 9.268811e-01 FALSE
## 2246 rs5998 6 445 1.287069e-01 1.000000e+00 9.268811e-01 FALSE
## 2247 rs7572 8 410 1.287929e-01 1.000000e+00 9.268811e-01 FALSE
## 2248 rs193 1 193 1.288722e-01 1.000000e+00 9.268811e-01 FALSE
## 2249 rs6698 7 320 1.289362e-01 1.000000e+00 9.268811e-01 FALSE
## 2250 rs5967 6 414 1.289472e-01 1.000000e+00 9.268811e-01 FALSE
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## 2340 rs3828 4 97 1.336307e-01 1.000000e+00 9.268811e-01 FALSE
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## 2343 rs14594 19 318 1.337456e-01 1.000000e+00 9.268811e-01 FALSE
## 2344 rs9303 10 670 1.337813e-01 1.000000e+00 9.268811e-01 FALSE
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## 2409 rs5781 6 228 1.369554e-01 1.000000e+00 9.268811e-01 FALSE
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## 2414 rs7279 8 117 1.371282e-01 1.000000e+00 9.268811e-01 FALSE
## 2415 rs11486 14 190 1.371664e-01 1.000000e+00 9.268811e-01 FALSE
## 2416 rs14917 20 79 1.373068e-01 1.000000e+00 9.268811e-01 FALSE
## 2417 rs14006 18 302 1.373793e-01 1.000000e+00 9.268811e-01 FALSE
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## 2420 rs13510 17 389 1.375051e-01 1.000000e+00 9.268811e-01 FALSE
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## 2425 rs6670 7 292 1.378830e-01 1.000000e+00 9.268811e-01 FALSE
## 2426 rs9578 11 249 1.378854e-01 1.000000e+00 9.268811e-01 FALSE
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## 2428 rs9466 11 137 1.379748e-01 1.000000e+00 9.268811e-01 FALSE
## 2429 rs7381 8 219 1.380638e-01 1.000000e+00 9.268811e-01 FALSE
## 2430 rs1228 1 1228 1.381126e-01 1.000000e+00 9.268811e-01 FALSE
## 2431 rs12504 15 586 1.381130e-01 1.000000e+00 9.268811e-01 FALSE
## 2432 rs7150 7 772 1.381578e-01 1.000000e+00 9.268811e-01 FALSE
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## 2437 rs10169 12 166 1.383535e-01 1.000000e+00 9.268811e-01 FALSE
## 2438 rs4609 4 878 1.386243e-01 1.000000e+00 9.268811e-01 FALSE
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## 2494 rs3097 3 406 1.423966e-01 1.000000e+00 9.268811e-01 FALSE
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## 2497 rs9649 11 320 1.424929e-01 1.000000e+00 9.268811e-01 FALSE
## 2498 rs8306 9 394 1.425215e-01 1.000000e+00 9.268811e-01 FALSE
## 2499 rs5519 5 843 1.425395e-01 1.000000e+00 9.268811e-01 FALSE
## 2500 rs8018 9 106 1.425999e-01 1.000000e+00 9.268811e-01 FALSE
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## 2518 rs9514 11 185 1.434168e-01 1.000000e+00 9.268811e-01 FALSE
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## 2520 rs3682 3 991 1.435019e-01 1.000000e+00 9.268811e-01 FALSE
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## 2530 rs5968 6 415 1.442713e-01 1.000000e+00 9.268811e-01 FALSE
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## 2536 rs12786 16 260 1.445460e-01 1.000000e+00 9.268811e-01 FALSE
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## 3000 rs7940 9 28 1.697197e-01 1.000000e+00 9.304826e-01 FALSE
## 3001 rs1631 2 131 1.698936e-01 1.000000e+00 9.304826e-01 FALSE
## 3002 rs8279 9 367 1.700066e-01 1.000000e+00 9.304826e-01 FALSE
## 3003 rs9629 11 300 1.700313e-01 1.000000e+00 9.304826e-01 FALSE
## 3004 rs6823 7 445 1.700743e-01 1.000000e+00 9.304826e-01 FALSE
## 3005 rs5807 6 254 1.701315e-01 1.000000e+00 9.304826e-01 FALSE
## 3006 rs147 1 147 1.701625e-01 1.000000e+00 9.304826e-01 FALSE
## 3007 rs13536 17 415 1.701651e-01 1.000000e+00 9.304826e-01 FALSE
## 3008 rs15187 20 349 1.701923e-01 1.000000e+00 9.304826e-01 FALSE
## 3009 rs14086 18 382 1.701934e-01 1.000000e+00 9.304826e-01 FALSE
## 3010 rs5952 6 399 1.702283e-01 1.000000e+00 9.304826e-01 FALSE
## 3011 rs14852 20 14 1.702546e-01 1.000000e+00 9.304826e-01 FALSE
## 3012 rs9132 10 499 1.703057e-01 1.000000e+00 9.304826e-01 FALSE
## 3013 rs3111 3 420 1.703699e-01 1.000000e+00 9.304826e-01 FALSE
## 3014 rs8058 9 146 1.703878e-01 1.000000e+00 9.304826e-01 FALSE
## 3015 rs1538 2 38 1.704267e-01 1.000000e+00 9.304826e-01 FALSE
## 3016 rs1032 1 1032 1.704722e-01 1.000000e+00 9.304826e-01 FALSE
## 3017 rs6152 6 599 1.704892e-01 1.000000e+00 9.304826e-01 FALSE
## 3018 rs14116 18 412 1.705037e-01 1.000000e+00 9.304826e-01 FALSE
## 3019 rs7869 8 707 1.705633e-01 1.000000e+00 9.304991e-01 FALSE
## 3020 rs8711 10 78 1.707506e-01 1.000000e+00 9.306504e-01 FALSE
## 3021 rs4397 4 666 1.707871e-01 1.000000e+00 9.306504e-01 FALSE
## 3022 rs11614 14 318 1.708415e-01 1.000000e+00 9.306504e-01 FALSE
## 3023 rs6904 7 526 1.709051e-01 1.000000e+00 9.306504e-01 FALSE
## 3024 rs9780 11 451 1.709886e-01 1.000000e+00 9.306504e-01 FALSE
## 3025 rs286 1 286 1.709964e-01 1.000000e+00 9.306504e-01 FALSE
## 3026 rs11156 13 498 1.710096e-01 1.000000e+00 9.306504e-01 FALSE
## 3027 rs9297 10 664 1.710430e-01 1.000000e+00 9.306504e-01 FALSE
## 3028 rs6272 6 719 1.712068e-01 1.000000e+00 9.310123e-01 FALSE
## 3029 rs58 1 58 1.712643e-01 1.000000e+00 9.310123e-01 FALSE
## 3030 rs3863 4 132 1.713123e-01 1.000000e+00 9.310123e-01 FALSE
## 3031 rs6142 6 589 1.713657e-01 1.000000e+00 9.310123e-01 FALSE
## 3032 rs8915 10 282 1.713922e-01 1.000000e+00 9.310123e-01 FALSE
## 3033 rs15496 21 105 1.715272e-01 1.000000e+00 9.311501e-01 FALSE
## 3034 rs850 1 850 1.715413e-01 1.000000e+00 9.311501e-01 FALSE
## 3035 rs222 1 222 1.716321e-01 1.000000e+00 9.311501e-01 FALSE
## 3036 rs13969 18 265 1.716437e-01 1.000000e+00 9.311501e-01 FALSE
## 3037 rs6882 7 504 1.718047e-01 1.000000e+00 9.312183e-01 FALSE
## 3038 rs9137 10 504 1.718141e-01 1.000000e+00 9.312183e-01 FALSE
## 3039 rs11657 14 361 1.718966e-01 1.000000e+00 9.312183e-01 FALSE
## 3040 rs7409 8 247 1.719429e-01 1.000000e+00 9.312183e-01 FALSE
## 3041 rs4994 5 318 1.719480e-01 1.000000e+00 9.312183e-01 FALSE
## 3042 rs1853 2 353 1.720078e-01 1.000000e+00 9.312183e-01 FALSE
## 3043 rs9280 10 647 1.720522e-01 1.000000e+00 9.312183e-01 FALSE
## 3044 rs14445 19 169 1.721148e-01 1.000000e+00 9.312183e-01 FALSE
## 3045 rs6483 7 105 1.722243e-01 1.000000e+00 9.312183e-01 FALSE
## 3046 rs10052 12 49 1.723783e-01 1.000000e+00 9.312183e-01 FALSE
## 3047 rs9947 11 618 1.726890e-01 1.000000e+00 9.312183e-01 FALSE
## 3048 rs4552 4 821 1.726911e-01 1.000000e+00 9.312183e-01 FALSE
## 3049 rs14950 20 112 1.727660e-01 1.000000e+00 9.312183e-01 FALSE
## 3050 rs6679 7 301 1.728382e-01 1.000000e+00 9.312183e-01 FALSE
## 3051 rs6325 6 772 1.728896e-01 1.000000e+00 9.312183e-01 FALSE
## 3052 rs479 1 479 1.730012e-01 1.000000e+00 9.312183e-01 FALSE
## 3053 rs15547 21 156 1.730798e-01 1.000000e+00 9.312183e-01 FALSE
## 3054 rs3653 3 962 1.731555e-01 1.000000e+00 9.312183e-01 FALSE
## 3055 rs5700 6 147 1.732439e-01 1.000000e+00 9.312183e-01 FALSE
## 3056 rs12397 15 479 1.733571e-01 1.000000e+00 9.312183e-01 FALSE
## 3057 rs11964 15 46 1.734595e-01 1.000000e+00 9.312183e-01 FALSE
## 3058 rs14447 19 171 1.734894e-01 1.000000e+00 9.312183e-01 FALSE
## 3059 rs9080 10 447 1.735072e-01 1.000000e+00 9.312183e-01 FALSE
## 3060 rs8582 9 670 1.735567e-01 1.000000e+00 9.312183e-01 FALSE
## 3061 rs3362 3 671 1.735608e-01 1.000000e+00 9.312183e-01 FALSE
## 3062 rs12088 15 170 1.735820e-01 1.000000e+00 9.312183e-01 FALSE
## 3063 rs2175 2 675 1.736146e-01 1.000000e+00 9.312183e-01 FALSE
## 3064 rs10640 12 637 1.739095e-01 1.000000e+00 9.312183e-01 FALSE
## 3065 rs12676 16 150 1.739181e-01 1.000000e+00 9.312183e-01 FALSE
## 3066 rs12849 16 323 1.739740e-01 1.000000e+00 9.312183e-01 FALSE
## 3067 rs13967 18 263 1.740151e-01 1.000000e+00 9.312183e-01 FALSE
## 3068 rs4546 4 815 1.740302e-01 1.000000e+00 9.312183e-01 FALSE
## 3069 rs10599 12 596 1.741261e-01 1.000000e+00 9.312183e-01 FALSE
## 3070 rs12144 15 226 1.742059e-01 1.000000e+00 9.312183e-01 FALSE
## 3071 rs11577 14 281 1.742526e-01 1.000000e+00 9.312183e-01 FALSE
## 3072 rs10639 12 636 1.742536e-01 1.000000e+00 9.312183e-01 FALSE
## 3073 rs6361 6 808 1.743233e-01 1.000000e+00 9.312183e-01 FALSE
## 3074 rs10020 12 17 1.743398e-01 1.000000e+00 9.312183e-01 FALSE
## 3075 rs4207 4 476 1.743505e-01 1.000000e+00 9.312183e-01 FALSE
## 3076 rs8990 10 357 1.744759e-01 1.000000e+00 9.312183e-01 FALSE
## 3077 rs7703 8 541 1.744834e-01 1.000000e+00 9.312183e-01 FALSE
## 3078 rs12800 16 274 1.745072e-01 1.000000e+00 9.312183e-01 FALSE
## 3079 rs544 1 544 1.745280e-01 1.000000e+00 9.312183e-01 FALSE
## 3080 rs14176 18 472 1.745458e-01 1.000000e+00 9.312183e-01 FALSE
## 3081 rs4489 4 758 1.747292e-01 1.000000e+00 9.312183e-01 FALSE
## 3082 rs10116 12 113 1.749334e-01 1.000000e+00 9.312183e-01 FALSE
## 3083 rs1898 2 398 1.749811e-01 1.000000e+00 9.312183e-01 FALSE
## 3084 rs10541 12 538 1.750772e-01 1.000000e+00 9.312183e-01 FALSE
## 3085 rs7903 8 741 1.751115e-01 1.000000e+00 9.312183e-01 FALSE
## 3086 rs15451 21 60 1.751533e-01 1.000000e+00 9.312183e-01 FALSE
## 3087 rs7921 9 9 1.752147e-01 1.000000e+00 9.312183e-01 FALSE
## 3088 rs2118 2 618 1.752304e-01 1.000000e+00 9.312183e-01 FALSE
## 3089 rs14951 20 113 1.752492e-01 1.000000e+00 9.312183e-01 FALSE
## 3090 rs5853 6 300 1.753491e-01 1.000000e+00 9.312183e-01 FALSE
## 3091 rs14666 19 390 1.753813e-01 1.000000e+00 9.312183e-01 FALSE
## 3092 rs7004 7 626 1.754017e-01 1.000000e+00 9.312183e-01 FALSE
## 3093 rs2369 2 869 1.754099e-01 1.000000e+00 9.312183e-01 FALSE
## 3094 rs6397 7 19 1.754338e-01 1.000000e+00 9.312183e-01 FALSE
## 3095 rs12305 15 387 1.755187e-01 1.000000e+00 9.312183e-01 FALSE
## 3096 rs14247 18 543 1.755716e-01 1.000000e+00 9.312183e-01 FALSE
## 3097 rs7555 8 393 1.756611e-01 1.000000e+00 9.312183e-01 FALSE
## 3098 rs12308 15 390 1.756975e-01 1.000000e+00 9.312183e-01 FALSE
## 3099 rs15554 21 163 1.757120e-01 1.000000e+00 9.312183e-01 FALSE
## 3100 rs3351 3 660 1.757272e-01 1.000000e+00 9.312183e-01 FALSE
## 3101 rs13201 17 80 1.757679e-01 1.000000e+00 9.312183e-01 FALSE
## 3102 rs1145 1 1145 1.758479e-01 1.000000e+00 9.312183e-01 FALSE
## 3103 rs15366 20 528 1.759119e-01 1.000000e+00 9.312183e-01 FALSE
## 3104 rs12492 15 574 1.759568e-01 1.000000e+00 9.312183e-01 FALSE
## 3105 rs10814 13 156 1.760515e-01 1.000000e+00 9.312183e-01 FALSE
## 3106 rs13337 17 216 1.760891e-01 1.000000e+00 9.312183e-01 FALSE
## 3107 rs12351 15 433 1.761765e-01 1.000000e+00 9.312183e-01 FALSE
## 3108 rs6977 7 599 1.764724e-01 1.000000e+00 9.312183e-01 FALSE
## 3109 rs7806 8 644 1.765363e-01 1.000000e+00 9.312183e-01 FALSE
## 3110 rs5774 6 221 1.765680e-01 1.000000e+00 9.312183e-01 FALSE
## 3111 rs14522 19 246 1.765743e-01 1.000000e+00 9.312183e-01 FALSE
## 3112 rs14189 18 485 1.765759e-01 1.000000e+00 9.312183e-01 FALSE
## 3113 rs9835 11 506 1.765926e-01 1.000000e+00 9.312183e-01 FALSE
## 3114 rs4463 4 732 1.766164e-01 1.000000e+00 9.312183e-01 FALSE
## 3115 rs15011 20 173 1.766727e-01 1.000000e+00 9.312183e-01 FALSE
## 3116 rs14729 19 453 1.766768e-01 1.000000e+00 9.312183e-01 FALSE
## 3117 rs2924 3 233 1.768031e-01 1.000000e+00 9.312183e-01 FALSE
## 3118 rs7697 8 535 1.768797e-01 1.000000e+00 9.312183e-01 FALSE
## 3119 rs10194 12 191 1.769037e-01 1.000000e+00 9.312183e-01 FALSE
## 3120 rs11945 15 27 1.769661e-01 1.000000e+00 9.312183e-01 FALSE
## 3121 rs9119 10 486 1.770574e-01 1.000000e+00 9.312183e-01 FALSE
## 3122 rs6849 7 471 1.770678e-01 1.000000e+00 9.312183e-01 FALSE
## 3123 rs502 1 502 1.771364e-01 1.000000e+00 9.312183e-01 FALSE
## 3124 rs13331 17 210 1.771522e-01 1.000000e+00 9.312183e-01 FALSE
## 3125 rs8110 9 198 1.771627e-01 1.000000e+00 9.312183e-01 FALSE
## 3126 rs14919 20 81 1.771710e-01 1.000000e+00 9.312183e-01 FALSE
## 3127 rs13042 16 516 1.771721e-01 1.000000e+00 9.312183e-01 FALSE
## 3128 rs11282 13 624 1.772657e-01 1.000000e+00 9.312183e-01 FALSE
## 3129 rs3798 4 67 1.773265e-01 1.000000e+00 9.312183e-01 FALSE
## 3130 rs1646 2 146 1.775364e-01 1.000000e+00 9.312183e-01 FALSE
## 3131 rs9717 11 388 1.776819e-01 1.000000e+00 9.312183e-01 FALSE
## 3132 rs3887 4 156 1.777227e-01 1.000000e+00 9.312183e-01 FALSE
## 3133 rs16300 22 365 1.778326e-01 1.000000e+00 9.312183e-01 FALSE
## 3134 rs11155 13 497 1.778500e-01 1.000000e+00 9.312183e-01 FALSE
## 3135 rs16468 22 533 1.778749e-01 1.000000e+00 9.312183e-01 FALSE
## 3136 rs6347 6 794 1.779406e-01 1.000000e+00 9.312183e-01 FALSE
## 3137 rs13925 18 221 1.779560e-01 1.000000e+00 9.312183e-01 FALSE
## 3138 rs1594 2 94 1.779620e-01 1.000000e+00 9.312183e-01 FALSE
## 3139 rs8419 9 507 1.780149e-01 1.000000e+00 9.312183e-01 FALSE
## 3140 rs15012 20 174 1.780670e-01 1.000000e+00 9.312183e-01 FALSE
## 3141 rs14035 18 331 1.780810e-01 1.000000e+00 9.312183e-01 FALSE
## 3142 rs15204 20 366 1.780943e-01 1.000000e+00 9.312183e-01 FALSE
## 3143 rs6308 6 755 1.784610e-01 1.000000e+00 9.312183e-01 FALSE
## 3144 rs2430 2 930 1.784936e-01 1.000000e+00 9.312183e-01 FALSE
## 3145 rs9314 10 681 1.785314e-01 1.000000e+00 9.312183e-01 FALSE
## 3146 rs3788 4 57 1.785591e-01 1.000000e+00 9.312183e-01 FALSE
## 3147 rs9196 10 563 1.785661e-01 1.000000e+00 9.312183e-01 FALSE
## 3148 rs4897 5 221 1.785921e-01 1.000000e+00 9.312183e-01 FALSE
## 3149 rs3647 3 956 1.785987e-01 1.000000e+00 9.312183e-01 FALSE
## 3150 rs3459 3 768 1.786117e-01 1.000000e+00 9.312183e-01 FALSE
## 3151 rs4727 5 51 1.786162e-01 1.000000e+00 9.312183e-01 FALSE
## 3152 rs15949 22 14 1.787140e-01 1.000000e+00 9.312183e-01 FALSE
## 3153 rs6757 7 379 1.788842e-01 1.000000e+00 9.312183e-01 FALSE
## 3154 rs6265 6 712 1.789085e-01 1.000000e+00 9.312183e-01 FALSE
## 3155 rs8964 10 331 1.790005e-01 1.000000e+00 9.312183e-01 FALSE
## 3156 rs7809 8 647 1.791135e-01 1.000000e+00 9.312183e-01 FALSE
## 3157 rs13949 18 245 1.791139e-01 1.000000e+00 9.312183e-01 FALSE
## 3158 rs16081 22 146 1.791662e-01 1.000000e+00 9.312183e-01 FALSE
## 3159 rs12540 16 14 1.791916e-01 1.000000e+00 9.312183e-01 FALSE
## 3160 rs4121 4 390 1.792546e-01 1.000000e+00 9.312183e-01 FALSE
## 3161 rs5208 5 532 1.792630e-01 1.000000e+00 9.312183e-01 FALSE
## 3162 rs11012 13 354 1.793467e-01 1.000000e+00 9.312183e-01 FALSE
## 3163 rs10030 12 27 1.793843e-01 1.000000e+00 9.312183e-01 FALSE
## 3164 rs5470 5 794 1.794176e-01 1.000000e+00 9.312183e-01 FALSE
## 3165 rs14664 19 388 1.794506e-01 1.000000e+00 9.312183e-01 FALSE
## 3166 rs6025 6 472 1.795359e-01 1.000000e+00 9.312183e-01 FALSE
## 3167 rs166 1 166 1.795557e-01 1.000000e+00 9.312183e-01 FALSE
## 3168 rs8680 10 47 1.795888e-01 1.000000e+00 9.312183e-01 FALSE
## 3169 rs13050 16 524 1.796272e-01 1.000000e+00 9.312183e-01 FALSE
## 3170 rs15663 21 272 1.796320e-01 1.000000e+00 9.312183e-01 FALSE
## 3171 rs1481 1 1481 1.796933e-01 1.000000e+00 9.312183e-01 FALSE
## 3172 rs1351 1 1351 1.797139e-01 1.000000e+00 9.312183e-01 FALSE
## 3173 rs11929 15 11 1.797814e-01 1.000000e+00 9.312183e-01 FALSE
## 3174 rs11412 14 116 1.798168e-01 1.000000e+00 9.312183e-01 FALSE
## 3175 rs13423 17 302 1.798382e-01 1.000000e+00 9.312183e-01 FALSE
## 3176 rs1672 2 172 1.798482e-01 1.000000e+00 9.312183e-01 FALSE
## 3177 rs11176 13 518 1.798989e-01 1.000000e+00 9.312183e-01 FALSE
## 3178 rs14019 18 315 1.799818e-01 1.000000e+00 9.312183e-01 FALSE
## 3179 rs8760 10 127 1.800019e-01 1.000000e+00 9.312183e-01 FALSE
## 3180 rs1909 2 409 1.802388e-01 1.000000e+00 9.312183e-01 FALSE
## 3181 rs13760 18 56 1.802537e-01 1.000000e+00 9.312183e-01 FALSE
## 3182 rs8878 10 245 1.803535e-01 1.000000e+00 9.312183e-01 FALSE
## 3183 rs13503 17 382 1.804039e-01 1.000000e+00 9.312183e-01 FALSE
## 3184 rs15333 20 495 1.804473e-01 1.000000e+00 9.312183e-01 FALSE
## 3185 rs8704 10 71 1.805159e-01 1.000000e+00 9.312183e-01 FALSE
## 3186 rs1277 1 1277 1.805392e-01 1.000000e+00 9.312183e-01 FALSE
## 3187 rs8512 9 600 1.805937e-01 1.000000e+00 9.312183e-01 FALSE
## 3188 rs7766 8 604 1.806118e-01 1.000000e+00 9.312183e-01 FALSE
## 3189 rs3416 3 725 1.810251e-01 1.000000e+00 9.312183e-01 FALSE
## 3190 rs6398 7 20 1.810361e-01 1.000000e+00 9.312183e-01 FALSE
## 3191 rs12266 15 348 1.811937e-01 1.000000e+00 9.312183e-01 FALSE
## 3192 rs1428 1 1428 1.813394e-01 1.000000e+00 9.312183e-01 FALSE
## 3193 rs8212 9 300 1.814659e-01 1.000000e+00 9.312183e-01 FALSE
## 3194 rs12042 15 124 1.816119e-01 1.000000e+00 9.312183e-01 FALSE
## 3195 rs5726 6 173 1.816575e-01 1.000000e+00 9.312183e-01 FALSE
## 3196 rs14879 20 41 1.816615e-01 1.000000e+00 9.312183e-01 FALSE
## 3197 rs10817 13 159 1.816622e-01 1.000000e+00 9.312183e-01 FALSE
## 3198 rs11213 13 555 1.816857e-01 1.000000e+00 9.312183e-01 FALSE
## 3199 rs2887 3 196 1.817271e-01 1.000000e+00 9.312183e-01 FALSE
## 3200 rs6819 7 441 1.817405e-01 1.000000e+00 9.312183e-01 FALSE
## 3201 rs15486 21 95 1.817410e-01 1.000000e+00 9.312183e-01 FALSE
## 3202 rs10578 12 575 1.817555e-01 1.000000e+00 9.312183e-01 FALSE
## 3203 rs6082 6 529 1.817871e-01 1.000000e+00 9.312183e-01 FALSE
## 3204 rs2731 3 40 1.818104e-01 1.000000e+00 9.312183e-01 FALSE
## 3205 rs6569 7 191 1.818516e-01 1.000000e+00 9.312183e-01 FALSE
## 3206 rs11345 14 49 1.818977e-01 1.000000e+00 9.312183e-01 FALSE
## 3207 rs8307 9 395 1.819006e-01 1.000000e+00 9.312183e-01 FALSE
## 3208 rs6805 7 427 1.819233e-01 1.000000e+00 9.312183e-01 FALSE
## 3209 rs15736 21 345 1.819289e-01 1.000000e+00 9.312183e-01 FALSE
## 3210 rs12769 16 243 1.819828e-01 1.000000e+00 9.312183e-01 FALSE
## 3211 rs3988 4 257 1.820004e-01 1.000000e+00 9.312183e-01 FALSE
## 3212 rs9813 11 484 1.820210e-01 1.000000e+00 9.312183e-01 FALSE
## 3213 rs7115 7 737 1.820390e-01 1.000000e+00 9.312183e-01 FALSE
## 3214 rs868 1 868 1.820461e-01 1.000000e+00 9.312183e-01 FALSE
## 3215 rs4789 5 113 1.820535e-01 1.000000e+00 9.312183e-01 FALSE
## 3216 rs5935 6 382 1.820723e-01 1.000000e+00 9.312183e-01 FALSE
## 3217 rs7991 9 79 1.821289e-01 1.000000e+00 9.312183e-01 FALSE
## 3218 rs6075 6 522 1.821303e-01 1.000000e+00 9.312183e-01 FALSE
## 3219 rs14800 19 524 1.821819e-01 1.000000e+00 9.312183e-01 FALSE
## 3220 rs13287 17 166 1.822314e-01 1.000000e+00 9.312183e-01 FALSE
## 3221 rs2295 2 795 1.822439e-01 1.000000e+00 9.312183e-01 FALSE
## 3222 rs15376 20 538 1.823121e-01 1.000000e+00 9.312183e-01 FALSE
## 3223 rs9010 10 377 1.823336e-01 1.000000e+00 9.312183e-01 FALSE
## 3224 rs1204 1 1204 1.823693e-01 1.000000e+00 9.312183e-01 FALSE
## 3225 rs3290 3 599 1.823990e-01 1.000000e+00 9.312183e-01 FALSE
## 3226 rs8923 10 290 1.824195e-01 1.000000e+00 9.312183e-01 FALSE
## 3227 rs3668 3 977 1.824635e-01 1.000000e+00 9.312183e-01 FALSE
## 3228 rs754 1 754 1.825614e-01 1.000000e+00 9.312183e-01 FALSE
## 3229 rs14960 20 122 1.826133e-01 1.000000e+00 9.312183e-01 FALSE
## 3230 rs976 1 976 1.826651e-01 1.000000e+00 9.312183e-01 FALSE
## 3231 rs12569 16 43 1.826816e-01 1.000000e+00 9.312183e-01 FALSE
## 3232 rs12672 16 146 1.827550e-01 1.000000e+00 9.313042e-01 FALSE
## 3233 rs6663 7 285 1.831006e-01 1.000000e+00 9.325853e-01 FALSE
## 3234 rs15456 21 65 1.832525e-01 1.000000e+00 9.325853e-01 FALSE
## 3235 rs496 1 496 1.832878e-01 1.000000e+00 9.325853e-01 FALSE
## 3236 rs10425 12 422 1.833986e-01 1.000000e+00 9.325853e-01 FALSE
## 3237 rs9232 10 599 1.836494e-01 1.000000e+00 9.325853e-01 FALSE
## 3238 rs6454 7 76 1.836604e-01 1.000000e+00 9.325853e-01 FALSE
## 3239 rs2890 3 199 1.837454e-01 1.000000e+00 9.325853e-01 FALSE
## 3240 rs6224 6 671 1.839561e-01 1.000000e+00 9.325853e-01 FALSE
## 3241 rs6010 6 457 1.839728e-01 1.000000e+00 9.325853e-01 FALSE
## 3242 rs15539 21 148 1.840082e-01 1.000000e+00 9.325853e-01 FALSE
## 3243 rs1761 2 261 1.840356e-01 1.000000e+00 9.325853e-01 FALSE
## 3244 rs2083 2 583 1.840361e-01 1.000000e+00 9.325853e-01 FALSE
## 3245 rs15065 20 227 1.841540e-01 1.000000e+00 9.325853e-01 FALSE
## 3246 rs3910 4 179 1.842236e-01 1.000000e+00 9.325853e-01 FALSE
## 3247 rs10545 12 542 1.842950e-01 1.000000e+00 9.325853e-01 FALSE
## 3248 rs9829 11 500 1.843075e-01 1.000000e+00 9.325853e-01 FALSE
## 3249 rs2257 2 757 1.843372e-01 1.000000e+00 9.325853e-01 FALSE
## 3250 rs6353 6 800 1.844097e-01 1.000000e+00 9.325853e-01 FALSE
## 3251 rs8826 10 193 1.844543e-01 1.000000e+00 9.325853e-01 FALSE
## 3252 rs13347 17 226 1.845152e-01 1.000000e+00 9.325853e-01 FALSE
## 3253 rs6895 7 517 1.845474e-01 1.000000e+00 9.325853e-01 FALSE
## 3254 rs16326 22 391 1.846490e-01 1.000000e+00 9.325853e-01 FALSE
## 3255 rs11982 15 64 1.847006e-01 1.000000e+00 9.325853e-01 FALSE
## 3256 rs11810 14 514 1.848420e-01 1.000000e+00 9.325853e-01 FALSE
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## 3282 rs15283 20 445 1.864319e-01 1.000000e+00 9.325853e-01 FALSE
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## 3284 rs5056 5 380 1.865850e-01 1.000000e+00 9.325853e-01 FALSE
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## 3295 rs283 1 283 1.873567e-01 1.000000e+00 9.325853e-01 FALSE
## 3296 rs7899 8 737 1.874285e-01 1.000000e+00 9.325853e-01 FALSE
## 3297 rs4762 5 86 1.875238e-01 1.000000e+00 9.325853e-01 FALSE
## 3298 rs15556 21 165 1.875425e-01 1.000000e+00 9.325853e-01 FALSE
## 3299 rs11122 13 464 1.876344e-01 1.000000e+00 9.325853e-01 FALSE
## 3300 rs4140 4 409 1.877339e-01 1.000000e+00 9.325853e-01 FALSE
## 3301 rs9244 10 611 1.877493e-01 1.000000e+00 9.325853e-01 FALSE
## 3302 rs157 1 157 1.878690e-01 1.000000e+00 9.325853e-01 FALSE
## 3303 rs6592 7 214 1.878941e-01 1.000000e+00 9.325853e-01 FALSE
## 3304 rs1744 2 244 1.879642e-01 1.000000e+00 9.325853e-01 FALSE
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## 3307 rs7403 8 241 1.880778e-01 1.000000e+00 9.325853e-01 FALSE
## 3308 rs8274 9 362 1.881347e-01 1.000000e+00 9.325853e-01 FALSE
## 3309 rs2366 2 866 1.881860e-01 1.000000e+00 9.325853e-01 FALSE
## 3310 rs3853 4 122 1.882127e-01 1.000000e+00 9.325853e-01 FALSE
## 3311 rs3422 3 731 1.882639e-01 1.000000e+00 9.325853e-01 FALSE
## 3312 rs15686 21 295 1.883251e-01 1.000000e+00 9.325853e-01 FALSE
## 3313 rs13577 17 456 1.883418e-01 1.000000e+00 9.325853e-01 FALSE
## 3314 rs10997 13 339 1.883479e-01 1.000000e+00 9.325853e-01 FALSE
## 3315 rs3171 3 480 1.883815e-01 1.000000e+00 9.325853e-01 FALSE
## 3316 rs1759 2 259 1.884225e-01 1.000000e+00 9.325853e-01 FALSE
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## 3318 rs1564 2 64 1.884490e-01 1.000000e+00 9.325853e-01 FALSE
## 3319 rs15051 20 213 1.884759e-01 1.000000e+00 9.325853e-01 FALSE
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## 3325 rs468 1 468 1.887495e-01 1.000000e+00 9.325853e-01 FALSE
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## 3331 rs4604 4 873 1.892139e-01 1.000000e+00 9.325853e-01 FALSE
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## 3336 rs66 1 66 1.894739e-01 1.000000e+00 9.325853e-01 FALSE
## 3337 rs3634 3 943 1.894849e-01 1.000000e+00 9.325853e-01 FALSE
## 3338 rs2344 2 844 1.895573e-01 1.000000e+00 9.325853e-01 FALSE
## 3339 rs6011 6 458 1.895768e-01 1.000000e+00 9.325853e-01 FALSE
## 3340 rs11933 15 15 1.896822e-01 1.000000e+00 9.325853e-01 FALSE
## 3341 rs2298 2 798 1.896929e-01 1.000000e+00 9.325853e-01 FALSE
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## 3343 rs1588 2 88 1.897836e-01 1.000000e+00 9.325853e-01 FALSE
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## 3345 rs3791 4 60 1.898736e-01 1.000000e+00 9.325853e-01 FALSE
## 3346 rs4167 4 436 1.899141e-01 1.000000e+00 9.325853e-01 FALSE
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## 3349 rs2178 2 678 1.900065e-01 1.000000e+00 9.325853e-01 FALSE
## 3350 rs16106 22 171 1.900495e-01 1.000000e+00 9.325853e-01 FALSE
## 3351 rs1381 1 1381 1.900629e-01 1.000000e+00 9.325853e-01 FALSE
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## 3356 rs12068 15 150 1.904014e-01 1.000000e+00 9.325853e-01 FALSE
## 3357 rs1877 2 377 1.905865e-01 1.000000e+00 9.325853e-01 FALSE
## 3358 rs14536 19 260 1.905884e-01 1.000000e+00 9.325853e-01 FALSE
## 3359 rs6059 6 506 1.906986e-01 1.000000e+00 9.325853e-01 FALSE
## 3360 rs13786 18 82 1.907008e-01 1.000000e+00 9.325853e-01 FALSE
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## 3362 rs11746 14 450 1.908246e-01 1.000000e+00 9.325853e-01 FALSE
## 3363 rs15793 21 402 1.908832e-01 1.000000e+00 9.325853e-01 FALSE
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## 3370 rs6000 6 447 1.910716e-01 1.000000e+00 9.325853e-01 FALSE
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## 3392 rs12143 15 225 1.922129e-01 1.000000e+00 9.325853e-01 FALSE
## 3393 rs6863 7 485 1.922186e-01 1.000000e+00 9.325853e-01 FALSE
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## 3400 rs12881 16 355 1.925564e-01 1.000000e+00 9.326108e-01 FALSE
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## 3419 rs10564 12 561 1.937628e-01 1.000000e+00 9.326108e-01 FALSE
## 3420 rs8021 9 109 1.938194e-01 1.000000e+00 9.326108e-01 FALSE
## 3421 rs9275 10 642 1.938894e-01 1.000000e+00 9.326108e-01 FALSE
## 3422 rs13063 16 537 1.939224e-01 1.000000e+00 9.326108e-01 FALSE
## 3423 rs15792 21 401 1.939584e-01 1.000000e+00 9.326108e-01 FALSE
## 3424 rs4122 4 391 1.940553e-01 1.000000e+00 9.326108e-01 FALSE
## 3425 rs1384 1 1384 1.940889e-01 1.000000e+00 9.326108e-01 FALSE
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## 3428 rs7750 8 588 1.941910e-01 1.000000e+00 9.326108e-01 FALSE
## 3429 rs15264 20 426 1.942847e-01 1.000000e+00 9.326108e-01 FALSE
## 3430 rs12557 16 31 1.942885e-01 1.000000e+00 9.326108e-01 FALSE
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## 3432 rs12470 15 552 1.944620e-01 1.000000e+00 9.326108e-01 FALSE
## 3433 rs9296 10 663 1.945055e-01 1.000000e+00 9.326108e-01 FALSE
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## 3438 rs191 1 191 1.946761e-01 1.000000e+00 9.326108e-01 FALSE
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## 3441 rs14576 19 300 1.949455e-01 1.000000e+00 9.328814e-01 FALSE
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## 3443 rs7260 8 98 1.950158e-01 1.000000e+00 9.328814e-01 FALSE
## 3444 rs8470 9 558 1.951167e-01 1.000000e+00 9.329014e-01 FALSE
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## 3446 rs8587 9 675 1.953298e-01 1.000000e+00 9.330695e-01 FALSE
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## 3451 rs15818 21 427 1.956405e-01 1.000000e+00 9.330695e-01 FALSE
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## 3453 rs12263 15 345 1.956651e-01 1.000000e+00 9.330695e-01 FALSE
## 3454 rs12779 16 253 1.956783e-01 1.000000e+00 9.330695e-01 FALSE
## 3455 rs2215 2 715 1.958433e-01 1.000000e+00 9.335861e-01 FALSE
## 3456 rs14877 20 39 1.959486e-01 1.000000e+00 9.338174e-01 FALSE
## 3457 rs2316 2 816 1.960578e-01 1.000000e+00 9.338989e-01 FALSE
## 3458 rs14088 18 384 1.961226e-01 1.000000e+00 9.338989e-01 FALSE
## 3459 rs9591 11 262 1.961358e-01 1.000000e+00 9.338989e-01 FALSE
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## 3463 rs9660 11 331 1.964133e-01 1.000000e+00 9.340219e-01 FALSE
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## 3468 rs4377 4 646 1.967085e-01 1.000000e+00 9.341952e-01 FALSE
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## 3470 rs164 1 164 1.969945e-01 1.000000e+00 9.345260e-01 FALSE
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## 3478 rs75 1 75 1.974103e-01 1.000000e+00 9.348328e-01 FALSE
## 3479 rs6869 7 491 1.975416e-01 1.000000e+00 9.349397e-01 FALSE
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## 3487 rs721 1 721 1.979919e-01 1.000000e+00 9.349397e-01 FALSE
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## 3507 rs3599 3 908 1.993966e-01 1.000000e+00 9.352419e-01 FALSE
## 3508 rs15424 21 33 1.993984e-01 1.000000e+00 9.352419e-01 FALSE
## 3509 rs3501 3 810 1.994018e-01 1.000000e+00 9.352419e-01 FALSE
## 3510 rs4976 5 300 1.994177e-01 1.000000e+00 9.352419e-01 FALSE
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## 3559 rs3531 3 840 2.029948e-01 1.000000e+00 9.366878e-01 FALSE
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## 10233 rs3690 3 999 6.207327e-01 1.000000e+00 9.972183e-01 FALSE
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## 10238 rs15095 20 257 6.208762e-01 1.000000e+00 9.972183e-01 FALSE
## 10239 rs2092 2 592 6.210509e-01 1.000000e+00 9.972183e-01 FALSE
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## 10241 rs3450 3 759 6.211043e-01 1.000000e+00 9.972183e-01 FALSE
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## 10244 rs6235 6 682 6.211789e-01 1.000000e+00 9.972183e-01 FALSE
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## 10252 rs4574 4 843 6.214641e-01 1.000000e+00 9.972183e-01 FALSE
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## 10304 rs4621 4 890 6.244634e-01 1.000000e+00 9.972183e-01 FALSE
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## 10306 rs4022 4 291 6.245559e-01 1.000000e+00 9.972183e-01 FALSE
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## 10315 rs14025 18 321 6.255544e-01 1.000000e+00 9.972183e-01 FALSE
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## 10320 rs7863 8 701 6.256326e-01 1.000000e+00 9.972183e-01 FALSE
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## 10322 rs4126 4 395 6.257942e-01 1.000000e+00 9.972183e-01 FALSE
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## 10329 rs9902 11 573 6.260142e-01 1.000000e+00 9.972183e-01 FALSE
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## 10344 rs1466 1 1466 6.271505e-01 1.000000e+00 9.972183e-01 FALSE
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## 10386 rs9959 11 630 6.301548e-01 1.000000e+00 9.972183e-01 FALSE
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## 10389 rs9880 11 551 6.302720e-01 1.000000e+00 9.972183e-01 FALSE
## 10390 rs13845 18 141 6.304133e-01 1.000000e+00 9.972183e-01 FALSE
## 10391 rs6576 7 198 6.304332e-01 1.000000e+00 9.972183e-01 FALSE
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## 10394 rs15035 20 197 6.305454e-01 1.000000e+00 9.972183e-01 FALSE
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## 10398 rs5636 6 83 6.307119e-01 1.000000e+00 9.972183e-01 FALSE
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## 10409 rs1288 1 1288 6.311455e-01 1.000000e+00 9.972183e-01 FALSE
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## 10424 rs16258 22 323 6.320701e-01 1.000000e+00 9.972183e-01 FALSE
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## 10432 rs15126 20 288 6.324953e-01 1.000000e+00 9.972183e-01 FALSE
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## 10975 rs15962 22 27 6.656509e-01 1.000000e+00 9.972183e-01 FALSE
## 10976 rs13635 17 514 6.656811e-01 1.000000e+00 9.972183e-01 FALSE
## 10977 rs5582 6 29 6.656861e-01 1.000000e+00 9.972183e-01 FALSE
## 10978 rs12207 15 289 6.657601e-01 1.000000e+00 9.972183e-01 FALSE
## 10979 rs15170 20 332 6.657750e-01 1.000000e+00 9.972183e-01 FALSE
## 10980 rs449 1 449 6.658076e-01 1.000000e+00 9.972183e-01 FALSE
## 10981 rs1548 2 48 6.658538e-01 1.000000e+00 9.972183e-01 FALSE
## 10982 rs11335 14 39 6.659401e-01 1.000000e+00 9.972183e-01 FALSE
## 10983 rs3723 3 1032 6.659858e-01 1.000000e+00 9.972183e-01 FALSE
## 10984 rs9837 11 508 6.661097e-01 1.000000e+00 9.972183e-01 FALSE
## 10985 rs13679 17 558 6.661216e-01 1.000000e+00 9.972183e-01 FALSE
## 10986 rs9534 11 205 6.661912e-01 1.000000e+00 9.972183e-01 FALSE
## 10987 rs13279 17 158 6.661925e-01 1.000000e+00 9.972183e-01 FALSE
## 10988 rs6875 7 497 6.662861e-01 1.000000e+00 9.972183e-01 FALSE
## 10989 rs8334 9 422 6.663169e-01 1.000000e+00 9.972183e-01 FALSE
## 10990 rs6424 7 46 6.664574e-01 1.000000e+00 9.972183e-01 FALSE
## 10991 rs5783 6 230 6.664677e-01 1.000000e+00 9.972183e-01 FALSE
## 10992 rs14337 19 61 6.665063e-01 1.000000e+00 9.972183e-01 FALSE
## 10993 rs7406 8 244 6.665415e-01 1.000000e+00 9.972183e-01 FALSE
## 10994 rs3683 3 992 6.665966e-01 1.000000e+00 9.972183e-01 FALSE
## 10995 rs7500 8 338 6.666926e-01 1.000000e+00 9.972183e-01 FALSE
## 10996 rs1618 2 118 6.667250e-01 1.000000e+00 9.972183e-01 FALSE
## 10997 rs2018 2 518 6.667454e-01 1.000000e+00 9.972183e-01 FALSE
## 10998 rs7370 8 208 6.667681e-01 1.000000e+00 9.972183e-01 FALSE
## 10999 rs2109 2 609 6.668145e-01 1.000000e+00 9.972183e-01 FALSE
## 11000 rs13687 17 566 6.668681e-01 1.000000e+00 9.972183e-01 FALSE
## 11001 rs14540 19 264 6.669098e-01 1.000000e+00 9.972183e-01 FALSE
## 11002 rs6747 7 369 6.669587e-01 1.000000e+00 9.972183e-01 FALSE
## 11003 rs547 1 547 6.669713e-01 1.000000e+00 9.972183e-01 FALSE
## 11004 rs16273 22 338 6.670029e-01 1.000000e+00 9.972183e-01 FALSE
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## 11006 rs4150 4 419 6.671492e-01 1.000000e+00 9.972183e-01 FALSE
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## 11008 rs1210 1 1210 6.672454e-01 1.000000e+00 9.972183e-01 FALSE
## 11009 rs6960 7 582 6.672546e-01 1.000000e+00 9.972183e-01 FALSE
## 11010 rs7910 8 748 6.672993e-01 1.000000e+00 9.972183e-01 FALSE
## 11011 rs11611 14 315 6.674128e-01 1.000000e+00 9.972183e-01 FALSE
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## 11015 rs16263 22 328 6.677168e-01 1.000000e+00 9.972183e-01 FALSE
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## 11018 rs6089 6 536 6.679908e-01 1.000000e+00 9.972183e-01 FALSE
## 11019 rs10585 12 582 6.680305e-01 1.000000e+00 9.972183e-01 FALSE
## 11020 rs12681 16 155 6.681761e-01 1.000000e+00 9.972183e-01 FALSE
## 11021 rs4494 4 763 6.682420e-01 1.000000e+00 9.972183e-01 FALSE
## 11022 rs2058 2 558 6.682720e-01 1.000000e+00 9.972183e-01 FALSE
## 11023 rs7026 7 648 6.683327e-01 1.000000e+00 9.972183e-01 FALSE
## 11024 rs8569 9 657 6.684706e-01 1.000000e+00 9.972183e-01 FALSE
## 11025 rs12662 16 136 6.685704e-01 1.000000e+00 9.972183e-01 FALSE
## 11026 rs14362 19 86 6.686776e-01 1.000000e+00 9.972183e-01 FALSE
## 11027 rs14641 19 365 6.686989e-01 1.000000e+00 9.972183e-01 FALSE
## 11028 rs13379 17 258 6.687818e-01 1.000000e+00 9.972183e-01 FALSE
## 11029 rs7184 8 22 6.688396e-01 1.000000e+00 9.972183e-01 FALSE
## 11030 rs9495 11 166 6.689690e-01 1.000000e+00 9.972183e-01 FALSE
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## 11032 rs7524 8 362 6.691500e-01 1.000000e+00 9.972183e-01 FALSE
## 11033 rs6966 7 588 6.691509e-01 1.000000e+00 9.972183e-01 FALSE
## 11034 rs8191 9 279 6.692151e-01 1.000000e+00 9.972183e-01 FALSE
## 11035 rs11630 14 334 6.692198e-01 1.000000e+00 9.972183e-01 FALSE
## 11036 rs3868 4 137 6.693869e-01 1.000000e+00 9.972183e-01 FALSE
## 11037 rs3233 3 542 6.693979e-01 1.000000e+00 9.972183e-01 FALSE
## 11038 rs1810 2 310 6.694079e-01 1.000000e+00 9.972183e-01 FALSE
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## 11040 rs2441 2 941 6.695589e-01 1.000000e+00 9.972183e-01 FALSE
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## 11042 rs10593 12 590 6.697067e-01 1.000000e+00 9.972183e-01 FALSE
## 11043 rs3633 3 942 6.697308e-01 1.000000e+00 9.972183e-01 FALSE
## 11044 rs12935 16 409 6.699603e-01 1.000000e+00 9.972183e-01 FALSE
## 11045 rs2399 2 899 6.703298e-01 1.000000e+00 9.972183e-01 FALSE
## 11046 rs13165 17 44 6.703317e-01 1.000000e+00 9.972183e-01 FALSE
## 11047 rs4148 4 417 6.703617e-01 1.000000e+00 9.972183e-01 FALSE
## 11048 rs9384 11 55 6.704582e-01 1.000000e+00 9.972183e-01 FALSE
## 11049 rs5465 5 789 6.704653e-01 1.000000e+00 9.972183e-01 FALSE
## 11050 rs4177 4 446 6.705168e-01 1.000000e+00 9.972183e-01 FALSE
## 11051 rs6351 6 798 6.705501e-01 1.000000e+00 9.972183e-01 FALSE
## 11052 rs2381 2 881 6.705754e-01 1.000000e+00 9.972183e-01 FALSE
## 11053 rs2452 2 952 6.706040e-01 1.000000e+00 9.972183e-01 FALSE
## 11054 rs7246 8 84 6.706295e-01 1.000000e+00 9.972183e-01 FALSE
## 11055 rs7308 8 146 6.707039e-01 1.000000e+00 9.972183e-01 FALSE
## 11056 rs793 1 793 6.707601e-01 1.000000e+00 9.972183e-01 FALSE
## 11057 rs6523 7 145 6.707612e-01 1.000000e+00 9.972183e-01 FALSE
## 11058 rs8796 10 163 6.707705e-01 1.000000e+00 9.972183e-01 FALSE
## 11059 rs9417 11 88 6.708257e-01 1.000000e+00 9.972183e-01 FALSE
## 11060 rs9606 11 277 6.708823e-01 1.000000e+00 9.972183e-01 FALSE
## 11061 rs10552 12 549 6.709170e-01 1.000000e+00 9.972183e-01 FALSE
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## 11063 rs1196 1 1196 6.710191e-01 1.000000e+00 9.972183e-01 FALSE
## 11064 rs5073 5 397 6.710207e-01 1.000000e+00 9.972183e-01 FALSE
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## 11066 rs8986 10 353 6.710520e-01 1.000000e+00 9.972183e-01 FALSE
## 11067 rs5795 6 242 6.710677e-01 1.000000e+00 9.972183e-01 FALSE
## 11068 rs3181 3 490 6.711006e-01 1.000000e+00 9.972183e-01 FALSE
## 11069 rs4152 4 421 6.711337e-01 1.000000e+00 9.972183e-01 FALSE
## 11070 rs6236 6 683 6.711752e-01 1.000000e+00 9.972183e-01 FALSE
## 11071 rs3848 4 117 6.712265e-01 1.000000e+00 9.972183e-01 FALSE
## 11072 rs12646 16 120 6.712534e-01 1.000000e+00 9.972183e-01 FALSE
## 11073 rs5846 6 293 6.713308e-01 1.000000e+00 9.972183e-01 FALSE
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## 11075 rs2258 2 758 6.716221e-01 1.000000e+00 9.972183e-01 FALSE
## 11076 rs9193 10 560 6.716393e-01 1.000000e+00 9.972183e-01 FALSE
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## 11078 rs15754 21 363 6.720612e-01 1.000000e+00 9.972183e-01 FALSE
## 11079 rs1524 2 24 6.721403e-01 1.000000e+00 9.972183e-01 FALSE
## 11080 rs13779 18 75 6.721814e-01 1.000000e+00 9.972183e-01 FALSE
## 11081 rs583 1 583 6.722162e-01 1.000000e+00 9.972183e-01 FALSE
## 11082 rs14085 18 381 6.722679e-01 1.000000e+00 9.972183e-01 FALSE
## 11083 rs7123 7 745 6.722816e-01 1.000000e+00 9.972183e-01 FALSE
## 11084 rs14527 19 251 6.723069e-01 1.000000e+00 9.972183e-01 FALSE
## 11085 rs8161 9 249 6.723682e-01 1.000000e+00 9.972183e-01 FALSE
## 11086 rs10315 12 312 6.724620e-01 1.000000e+00 9.972183e-01 FALSE
## 11087 rs14570 19 294 6.725278e-01 1.000000e+00 9.972183e-01 FALSE
## 11088 rs458 1 458 6.725682e-01 1.000000e+00 9.972183e-01 FALSE
## 11089 rs16216 22 281 6.726073e-01 1.000000e+00 9.972183e-01 FALSE
## 11090 rs2941 3 250 6.726423e-01 1.000000e+00 9.972183e-01 FALSE
## 11091 rs11372 14 76 6.726694e-01 1.000000e+00 9.972183e-01 FALSE
## 11092 rs1102 1 1102 6.727257e-01 1.000000e+00 9.972183e-01 FALSE
## 11093 rs1838 2 338 6.727657e-01 1.000000e+00 9.972183e-01 FALSE
## 11094 rs16090 22 155 6.727979e-01 1.000000e+00 9.972183e-01 FALSE
## 11095 rs9731 11 402 6.728941e-01 1.000000e+00 9.972183e-01 FALSE
## 11096 rs7236 8 74 6.730510e-01 1.000000e+00 9.972183e-01 FALSE
## 11097 rs7357 8 195 6.731317e-01 1.000000e+00 9.972183e-01 FALSE
## 11098 rs2014 2 514 6.732402e-01 1.000000e+00 9.972183e-01 FALSE
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## 11100 rs2353 2 853 6.733413e-01 1.000000e+00 9.972183e-01 FALSE
## 11101 rs4566 4 835 6.733504e-01 1.000000e+00 9.972183e-01 FALSE
## 11102 rs8944 10 311 6.733543e-01 1.000000e+00 9.972183e-01 FALSE
## 11103 rs4025 4 294 6.733909e-01 1.000000e+00 9.972183e-01 FALSE
## 11104 rs2346 2 846 6.733935e-01 1.000000e+00 9.972183e-01 FALSE
## 11105 rs14827 19 551 6.734037e-01 1.000000e+00 9.972183e-01 FALSE
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## 11107 rs1276 1 1276 6.735041e-01 1.000000e+00 9.972183e-01 FALSE
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## 11111 rs12173 15 255 6.735675e-01 1.000000e+00 9.972183e-01 FALSE
## sig_FDR sig_GWAS
## 1 TRUE TRUE
## 2 TRUE TRUE
## 3 TRUE TRUE
## 4 TRUE TRUE
## 5 TRUE TRUE
## 6 TRUE TRUE
## 7 TRUE FALSE
## 8 TRUE FALSE
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## 10 TRUE FALSE
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## 11111 FALSE FALSE
## [ reached 'max' / getOption("max.print") -- omitted 5359 rows ]
# Step 5: Find significant SNPs
sig_snps <- snp_clean %>%
filter(sig_bonferroni | sig_FDR | sig_GWAS) %>%
arrange(P)
cat("Significant SNPs:", nrow(sig_snps), "\n")
## Significant SNPs: 45
print(sig_snps)
## SNP CHR BP P p_bonferroni p_BH sig_bonferroni
## 1 rs3057 3 366 4.438922e-09 7.310904e-05 4.286281e-05 TRUE
## 2 rs3050 3 359 7.803872e-09 1.285298e-04 4.286281e-05 TRUE
## 3 rs3056 3 365 7.807433e-09 1.285884e-04 4.286281e-05 TRUE
## 4 rs3060 3 369 2.488724e-08 4.098929e-04 8.804538e-05 TRUE
## 5 rs3040 3 349 2.672902e-08 4.402269e-04 8.804538e-05 TRUE
## 6 rs3054 3 363 3.892246e-08 6.410528e-04 1.068421e-04 TRUE
## 7 rs3051 3 360 6.459032e-08 1.063803e-03 1.519718e-04 TRUE
## 8 rs3052 3 361 1.018498e-07 1.677467e-03 1.925831e-04 TRUE
## 9 rs3055 3 364 1.173634e-07 1.932976e-03 1.925831e-04 TRUE
## 10 rs3047 3 356 1.237451e-07 2.038082e-03 1.925831e-04 TRUE
## 11 rs3039 3 348 1.291335e-07 2.126829e-03 1.925831e-04 TRUE
## 12 rs3049 3 358 1.575144e-07 2.594263e-03 1.925831e-04 TRUE
## 13 rs3048 3 357 1.578447e-07 2.599702e-03 1.925831e-04 TRUE
## 14 rs3053 3 362 1.637015e-07 2.696164e-03 1.925831e-04 TRUE
## 15 rs3044 3 353 2.182527e-07 3.594623e-03 2.396415e-04 TRUE
## 16 rs3045 3 354 2.715654e-07 4.472682e-03 2.777781e-04 TRUE
## 17 rs3041 3 350 2.946537e-07 4.852947e-03 2.777781e-04 TRUE
## 18 rs3046 3 355 3.035826e-07 5.000005e-03 2.777781e-04 TRUE
## 19 rs3061 3 370 3.759351e-07 6.191651e-03 3.258764e-04 TRUE
## 20 rs3058 3 367 4.739185e-07 7.805437e-03 3.902719e-04 TRUE
## 21 rs3059 3 368 5.101074e-07 8.401470e-03 4.000700e-04 TRUE
## 22 rs3042 3 351 5.475278e-07 9.017782e-03 4.067937e-04 TRUE
## 23 rs3035 3 344 5.743707e-07 9.459885e-03 4.067937e-04 TRUE
## 24 rs3043 3 352 5.927777e-07 9.763049e-03 4.067937e-04 TRUE
## 25 rs3063 3 372 6.195479e-07 1.020395e-02 4.081581e-04 TRUE
## 26 rs3064 3 373 1.081160e-06 1.780671e-02 6.614120e-04 TRUE
## 27 rs3038 3 347 1.084282e-06 1.785812e-02 6.614120e-04 TRUE
## 28 rs3062 3 371 1.542880e-06 2.541123e-02 9.075441e-04 TRUE
## 29 rs3066 3 375 1.658165e-06 2.730998e-02 9.417234e-04 TRUE
## 30 rs3065 3 374 2.140884e-06 3.526036e-02 1.175345e-03 TRUE
## 31 rs3070 3 379 2.310487e-06 3.805372e-02 1.227539e-03 TRUE
## 32 rs3037 3 346 2.537116e-06 4.178631e-02 1.305822e-03 TRUE
## 33 rs3068 3 377 2.755368e-06 4.538090e-02 1.375179e-03 TRUE
## 34 rs3036 3 345 3.702689e-06 6.098329e-02 1.793626e-03 FALSE
## 35 rs3034 3 343 6.093931e-06 1.003670e-01 2.867630e-03 FALSE
## 36 rs3067 3 376 8.671423e-06 1.428183e-01 3.967176e-03 FALSE
## 37 rs3033 3 342 1.320982e-05 2.175658e-01 5.880156e-03 FALSE
## 38 rs3032 3 341 1.593872e-05 2.625108e-01 6.773669e-03 FALSE
## 39 rs3069 3 378 1.603965e-05 2.641731e-01 6.773669e-03 FALSE
## 40 rs3030 3 339 1.798130e-05 2.961521e-01 7.403802e-03 FALSE
## 41 rs13895 18 191 2.635363e-05 4.340444e-01 1.058645e-02 FALSE
## 42 rs3031 3 340 2.976909e-05 4.902970e-01 1.167374e-02 FALSE
## 43 rs11846 14 550 4.936848e-05 8.130988e-01 1.890928e-02 FALSE
## 44 rs3029 3 338 7.079979e-05 1.000000e+00 2.650165e-02 FALSE
## 45 rs3071 3 380 8.000464e-05 1.000000e+00 2.928170e-02 FALSE
## sig_FDR sig_GWAS
## 1 TRUE TRUE
## 2 TRUE TRUE
## 3 TRUE TRUE
## 4 TRUE TRUE
## 5 TRUE TRUE
## 6 TRUE TRUE
## 7 TRUE FALSE
## 8 TRUE FALSE
## 9 TRUE FALSE
## 10 TRUE FALSE
## 11 TRUE FALSE
## 12 TRUE FALSE
## 13 TRUE FALSE
## 14 TRUE FALSE
## 15 TRUE FALSE
## 16 TRUE FALSE
## 17 TRUE FALSE
## 18 TRUE FALSE
## 19 TRUE FALSE
## 20 TRUE FALSE
## 21 TRUE FALSE
## 22 TRUE FALSE
## 23 TRUE FALSE
## 24 TRUE FALSE
## 25 TRUE FALSE
## 26 TRUE FALSE
## 27 TRUE FALSE
## 28 TRUE FALSE
## 29 TRUE FALSE
## 30 TRUE FALSE
## 31 TRUE FALSE
## 32 TRUE FALSE
## 33 TRUE FALSE
## 34 TRUE FALSE
## 35 TRUE FALSE
## 36 TRUE FALSE
## 37 TRUE FALSE
## 38 TRUE FALSE
## 39 TRUE FALSE
## 40 TRUE FALSE
## 41 TRUE FALSE
## 42 TRUE FALSE
## 43 TRUE FALSE
## 44 TRUE FALSE
## 45 TRUE FALSE
write_csv(sig_snps, "significant_SNPs_results.csv")